Protein Name ribosomal protein S6 kinase A3
Organism Homo sapiens
Gene ID 6197
Gene Symbol

RPS6KA3

UniProt P51812 (KS6A3_HUMAN), B4DG22 (B4DG22_HUMAN), B7ZB17 (B7ZB17_HUMAN), A0A384MDW3 (A0A384MDW3_HUMAN), B1AXG1 (B1AXG1_HUMAN)
Relationships Total Number of functionally related compound(s) : 131
Total Number of Articles : 142
Description

ribosomal protein S6 kinase A3

Gene Summary

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS). [provided by RefSeq, Jul 2008]

synonyms
  • ribosomal protein S6 kinase alpha-3
  • MAP kinase-activated protein kinase 1b
  • MAPK-activated protein kinase 1b
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Properties