Protein Name selectin, platelet
Organism Mus musculus
Gene ID 20344
Gene Symbol

Selp

UniProt Q01102 (LYAM3_MOUSE)
Relationships Total Number of functionally related compound(s) : 279
Total Number of Articles : 292
Description

selectin, platelet

Gene Summary

Enables calcium-dependent protein binding activity and sialic acid binding activity. Involved in positive regulation of leukocyte tethering or rolling and positive regulation of platelet activation. Acts upstream of or within several processes, including heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; leukocyte tethering or rolling; and positive regulation of leukocyte migration. Located in external side of plasma membrane. Is expressed in blood and liver. Human ortholog(s) of this gene implicated in atopic dermatitis and myocardial infarction. Orthologous to human SELP (selectin P). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • P-selectin
  • CD62 antigen-like family member P
  • granule membrane protein 140
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Properties