Protein Name hematopoietic SH2 domain containing
Organism Homo sapiens
Gene ID 84941
Gene Symbol

HSH2D

UniProt Q96JZ2 (HSH2D_HUMAN)
Relationships Total Number of functionally related compound(s) : 133
Total Number of Articles : 100
Description

hematopoietic SH2 domain containing

Gene Summary

T-cell activation requires 2 signals: recognition of antigen by the T-cell receptor (see TCR; MIM 186880) and a costimulatory signal provided primarily by CD28 (MIM 186760) in naive T cells. HSH2 is a target of both of these signaling pathways (Greene et al., 2003 [PubMed 12960172]).[supplied by OMIM, Mar 2008]

synonyms
  • hematopoietic SH2 domain-containing protein
  • adaptor in lymphocytes of unknown function X
  • ALX
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Properties