Protein Name prostaglandin E receptor 2 (subtype EP2)
Organism Mus musculus
Gene ID 19217
Gene Symbol

Ptger2

UniProt Q62053 (PE2R2_MOUSE), Q543A9 (Q543A9_MOUSE)
Relationships Total Number of functionally related compound(s) : 133
Total Number of Articles : 300
Description

prostaglandin E receptor 2 (subtype EP2)

Gene Summary

Predicted to enable prostaglandin E receptor activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; cellular response to prostaglandin E stimulus; and response to progesterone. Acts upstream of or within regulation of cell population proliferation and response to lipopolysaccharide. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including central nervous system; gut; hemolymphoid system gland; liver and biliary system; and reproductive system. Human ortholog(s) of this gene implicated in asthma, nasal polyps, and aspirin intolerance. Orthologous to human PTGER2 (prostaglandin E receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • prostaglandin E2 receptor EP2 subtype
  • EP2 receptor
  • PGE receptor EP2 subtype
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Properties