Protein Name BTB domain and CNC homolog 1
Organism Homo sapiens
Gene ID 571
Gene Symbol

BACH1

UniProt O14867 (BACH1_HUMAN)
Relationships Total Number of functionally related compound(s) : 120
Total Number of Articles : 144
Description

BTB domain and CNC homolog 1

Gene Summary

This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, May 2009]

synonyms
  • transcription regulator protein BACH1
  • BTB and CNC homology 1, basic leucine zipper transcription factor 1
  • basic region leucine zipper transcriptional regulator BACH1
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Properties