| Protein Name | eukaryotic translation initiation factor 2 alpha kinase 4 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 27103 |
| Gene Symbol | Eif2ak4 |
| UniProt | Q9QZ05 (E2AK4_MOUSE), A2AUM0 (A2AUM0_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
50
Total Number of Articles : 47 |
Description |
eukaryotic translation initiation factor 2 alpha kinase 4 |
| Gene Summary |
Enables eukaryotic translation initiation factor 2alpha kinase activity and tRNA binding activity. Involved in several processes, including GCN2-mediated signaling; learning or memory; and regulation of translational initiation. Acts upstream of or within cellular response to starvation; endoplasmic reticulum unfolded protein response; and regulation of translation. Located in cytoplasm. Is expressed in several structures, including gut; hemolymphoid system gland; liver; lung; and ovary. Human ortholog(s) of this gene implicated in pulmonary venoocclusive disease 2. Orthologous to human EIF2AK4 (eukaryotic translation initiation factor 2 alpha kinase 4). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |