Protein Name angiopoietin like 3
Organism Homo sapiens
Gene ID 27329
Gene Symbol

ANGPTL3

UniProt Q9Y5C1 (ANGL3_HUMAN)
Relationships Total Number of functionally related compound(s) : 69
Total Number of Articles : 157
Description

angiopoietin like 3

Gene Summary

This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2. [provided by RefSeq, Aug 2015]

synonyms
  • angiopoietin-related protein 3
  • angiopoietin 5
  • ANG-5
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Properties