Protein Name wingless-type MMTV integration site family, member 2
Organism Mus musculus
Gene ID 22413
Gene Symbol

Wnt2

UniProt P21552 (WNT2_MOUSE), Q8BRC7 (Q8BRC7_MOUSE)
Relationships Total Number of functionally related compound(s) : 47
Total Number of Articles : 44
Description

wingless-type MMTV integration site family, member 2

Gene Summary

Predicted to enable cytokine activity and frizzled binding activity. Involved in cell proliferation in midbrain and positive regulation of neurogenesis. Acts upstream of or within several processes, including circulatory system development; lung induction; and positive regulation of cell population proliferation. Predicted to be located in collagen-containing extracellular matrix and cytoplasm. Predicted to be extrinsic component of external side of plasma membrane. Predicted to be active in extracellular space. Is expressed in several structures, including embryo mesenchyme; face; heart and pericardium; reproductive system; and urethra. Human ortholog(s) of this gene implicated in breast carcinoma; hepatocellular carcinoma; and urinary system cancer. Orthologous to human WNT2 (Wnt family member 2). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • protein Wnt-2
  • INT-1-related protein
  • wingless-related MMTV integration site 2
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Properties