Protein Name baculoviral IAP repeat containing 2
Organism Homo sapiens
Gene ID 329
Gene Symbol

BIRC2

UniProt Q13490 (BIRC2_HUMAN)
Relationships Total Number of functionally related compound(s) : 259
Total Number of Articles : 304
Description

baculoviral IAP repeat containing 2

Gene Summary

The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

synonyms
  • baculoviral IAP repeat-containing protein 2
  • IAP homolog B
  • IAP-2
Click to show/hide the synonyms
Properties