Protein Name KLF transcription factor 5
Organism Homo sapiens
Gene ID 688
Gene Symbol

KLF5

UniProt Q13887 (KLF5_HUMAN), Q5T6X2 (Q5T6X2_HUMAN)
Relationships Total Number of functionally related compound(s) : 103
Total Number of Articles : 107
Description

KLF transcription factor 5

Gene Summary

This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. The encoded protein is a transcriptional activator that binds directly to a specific recognition motif in the promoters of target genes. This protein acts downstream of multiple different signaling pathways and is regulated by post-translational modification. It may participate in both promoting and suppressing cell proliferation. Expression of this gene may be changed in a variety of different cancers and in cardiovascular disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]

synonyms
  • Krueppel-like factor 5
  • (intestinal Kruppel-like factor
  • BTE-binding protein 2
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Properties