Protein Name sphingosine-1-phosphate receptor 1
Organism Rattus norvegicus
Gene ID 29733
Gene Symbol

S1pr1

UniProt P48303 (S1PR1_RAT)
Relationships Total Number of functionally related compound(s) : 117
Total Number of Articles : 118
Description

sphingosine-1-phosphate receptor 1

Gene Summary

Enables G protein-coupled receptor activity and sphingolipid binding activity. Involved in several processes, including G protein-coupled receptor signaling pathway; negative regulation of stress fiber assembly; and positive regulation of GTPase activity. Predicted to be located in external side of plasma membrane and nucleoplasm. Predicted to be intrinsic component of plasma membrane. Predicted to be active in cytoplasm and plasma membrane. Used to study hypertension. Orthologous to human S1PR1 (sphingosine-1-phosphate receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • sphingosine 1-phosphate receptor 1
  • EDG1 (Edg1)
  • S1P receptor 1
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Properties