Protein Name toll-like receptor 7
Organism Mus musculus
Gene ID 170743
Gene Symbol

Tlr7

UniProt P58681 (TLR7_MOUSE), Q548J0 (Q548J0_MOUSE), Q599W9 (Q599W9_MOUSE)
Relationships Total Number of functionally related compound(s) : 229
Total Number of Articles : 293
Description

toll-like receptor 7

Gene Summary

Enables siRNA binding activity and single-stranded RNA binding activity. Involved in several processes, including positive regulation of macromolecule metabolic process; response to virus; and toll-like receptor 7 signaling pathway. Acts upstream of or within positive regulation of interleukin-6 production and regulation of protein phosphorylation. Located in cytoplasmic vesicle; endoplasmic reticulum; and lysosome. Is expressed in brain and liver. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in COVID-19 and X-Linked immunodeficiency 74. Orthologous to human TLR7 (toll like receptor 7). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • toll-like receptor 7
  • Toll like receptor 7
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Properties