| Protein Name | cytochrome P450, family 46, subfamily a, polypeptide 1 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 362782 |
| Gene Symbol | Cyp46a1 |
| UniProt | F7EN52 (F7EN52_RAT), A0A0G2JWG7 (A0A0G2JWG7_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
5
Total Number of Articles : 9 |
Description |
cytochrome P450, family 46, subfamily a, polypeptide 1 |
| Gene Summary |
Predicted to enable cholesterol 24-hydroxylase activity; heme binding activity; and steroid hydroxylase activity. Predicted to be involved in regulation of long-term synaptic potentiation; steroid metabolic process; and xenobiotic metabolic process. Predicted to act upstream of with a negative effect on protein localization to membrane raft. Predicted to be located in several cellular components, including dendrite; endoplasmic reticulum membrane; and postsynapse. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human CYP46A1 (cytochrome P450 family 46 subfamily A member 1). [provided by Alliance of Genome Resources, Jul 2025] |
| synonyms |
|
| Properties | |