| Protein Name | occludin |
|---|---|
| Organism | Mus musculus |
| Gene ID | 18260 |
| Gene Symbol | Ocln |
| UniProt | Q61146 (OCLN_MOUSE), B2RS24 (B2RS24_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
340
Total Number of Articles : 394 |
Description |
occludin |
| Gene Summary |
Predicted to enable protein domain specific binding activity. Involved in negative regulation of gene expression and tight junction organization. Located in several cellular components, including apical plasma membrane; apicolateral plasma membrane; and bicellular tight junction. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in Crohn's disease and pseudo-TORCH syndrome 1. Orthologous to human OCLN (occludin). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |