Protein Name superoxide dismutase 3, extracellular
Organism Mus musculus
Gene ID 20657
Gene Symbol

Sod3

UniProt O09164 (SODE_MOUSE), Q542X9 (Q542X9_MOUSE)
Relationships Total Number of functionally related compound(s) : 127
Total Number of Articles : 174
Description

superoxide dismutase 3, extracellular

Gene Summary

Enables superoxide dismutase activity. Acts upstream of or within response to hypoxia. Located in extracellular space. Colocalizes with collagen-containing extracellular matrix. Is expressed in several structures, including alimentary system; central nervous system; extraembryonic component; genitourinary system; and neural ectoderm. Human ortholog(s) of this gene implicated in several diseases, including coronary artery disease (multiple); diabetes mellitus (multiple); diabetic retinopathy; lung disease (multiple); and polyneuropathy. Orthologous to human SOD3 (superoxide dismutase 3). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • extracellular superoxide dismutase [Cu-Zn]
  • extracellular superoxide dismutase
  • EC-SOD
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Properties