Protein Name GATA binding protein 4
Organism Homo sapiens
Gene ID 2626
Gene Symbol

GATA4

UniProt P43694 (GATA4_HUMAN), B6DU75 (B6DU75_HUMAN), B3KUF4 (B3KUF4_HUMAN)
Relationships Total Number of functionally related compound(s) : 139
Total Number of Articles : 175
Description

GATA binding protein 4

Gene Summary

This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function, and is necessary for normal testicular development. Mutations in this gene have been associated with cardiac septal defects. Additionally, alterations in gene expression have been associated with several cancer types. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

synonyms
  • transcription factor GATA-4
  • GATA-binding factor 4
  • ASD2
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Properties