| Protein Name | heat shock protein 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 15507 |
| Gene Symbol | Hspb1 |
| UniProt | P14602 (HSPB1_MOUSE), Q545F4 (Q545F4_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
236
Total Number of Articles : 236 |
Description |
heat shock protein 1 |
| Gene Summary |
Enables protein kinase C binding activity and protein kinase C inhibitor activity. Involved in negative regulation of protein kinase activity; positive regulation of cytokine production; and regulation of intracellular signal transduction. Acts upstream of or within negative regulation of apoptotic signaling pathway. Located in Z disc; nucleus; and plasma membrane. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and heart. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2F; distal hereditary motor neuropathy type 2B; pancreatic cancer; and sarcoma. Orthologous to human HSPB1 (heat shock protein family B (small) member 1). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |