Protein Name uncoupling protein 3
Organism Rattus norvegicus
Gene ID 25708
Gene Symbol

Ucp3

UniProt P56499 (UCP3_RAT)
Relationships Total Number of functionally related compound(s) : 115
Total Number of Articles : 129
Description

uncoupling protein 3

Gene Summary

Predicted to enable oxidative phosphorylation uncoupler activity. Involved in several processes, including response to activity; response to insulin; and response to superoxide. Located in mitochondrion. Used to study type 2 diabetes mellitus. Biomarker of congestive heart failure; hypertension; hyperthyroidism; hypothyroidism; and prediabetes syndrome. Human ortholog(s) of this gene implicated in coronary restenosis; diabetic neuropathy; glucose metabolism disease (multiple); and obesity. Orthologous to human UCP3 (uncoupling protein 3). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • putative mitochondrial transporter UCP3
  • UCP 3
  • Uncoupling protein 3, mitochondrial
Click to show/hide the synonyms
Properties