Protein Name leptin receptor
Organism Rattus norvegicus
Gene ID 24536
Gene Symbol

Lepr

UniProt Q62959 (LEPR_RAT)
Relationships Total Number of functionally related compound(s) : 86
Total Number of Articles : 91
Description

leptin receptor

Gene Summary

Enables peptide hormone binding activity and protein-hormone receptor activity. Involved in several processes, including gonad development; negative regulation of locomotor rhythm; and positive regulation of cell communication. Located in extracellular space and plasma membrane. Used to study several diseases, including chronic kidney disease; glucose metabolism disease (multiple); obesity; pancreatitis; and renal fibrosis. Biomarker of pre-eclampsia and short bowel syndrome. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); non-alcoholic fatty liver disease (multiple); obesity; obstructive sleep apnea; and type 2 diabetes mellitus. Orthologous to human LEPR (leptin receptor). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • leptin receptor
  • LEP-R
  • Leptin receptor (fatty)
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Properties