Protein Name leucine rich repeat containing G protein coupled receptor 5
Organism Mus musculus
Gene ID 14160
Gene Symbol

Lgr5

UniProt Q9Z1P4 (LGR5_MOUSE)
Relationships Total Number of functionally related compound(s) : 83
Total Number of Articles : 85
Description

leucine rich repeat containing G protein coupled receptor 5

Gene Summary

The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. [provided by RefSeq, Sep 2015]

synonyms
  • leucine-rich repeat-containing G-protein coupled receptor 5
  • G protein-coupled receptor 49
  • follicle expressed hormone
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Properties