| Protein Name | HCK proto-oncogene, Src family tyrosine kinase |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 3055 |
| Gene Symbol | HCK |
| UniProt | P08631 (HCK_HUMAN), A8K4G3 (A8K4G3_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
120
Total Number of Articles : 155 |
Description |
HCK proto-oncogene, Src family tyrosine kinase |
| Gene Summary |
The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon. [provided by RefSeq, Feb 2010] |
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