Protein Name | T cell immunoreceptor with Ig and ITIM domains |
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Organism | Homo sapiens |
Gene ID | 201633 |
Gene Symbol | TIGIT |
UniProt | Q495A1 (TIGIT_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
31
Total Number of Articles : 49 |
Description |
T cell immunoreceptor with Ig and ITIM domains |
Gene Summary |
This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq, Sep 2009] |
synonyms |
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Properties | |