Protein Name synuclein alpha
Organism Rattus norvegicus
Gene ID 29219
Gene Symbol

Snca

UniProt P37377 (SYUA_RAT)
Relationships Total Number of functionally related compound(s) : 268
Total Number of Articles : 355
Description

synuclein alpha

Gene Summary

Enables several functions, including phospholipase binding activity; protein N-terminus binding activity; and tubulin binding activity. Involved in several processes, including behavioral response to cocaine; negative regulation of nitrogen compound metabolic process; and response to desipramine. Located in several cellular components, including cytoplasmic vesicle; distal axon; and mitochondrion. Used to study Parkinson's disease and amphetamine abuse. Biomarker of mental depression and neurilemmoma. Human ortholog(s) of this gene implicated in Alzheimer's disease; Lewy body dementia; Parkinson's disease; Parkinson's disease 1; and Parkinson's disease 4. Orthologous to human SNCA (synuclein alpha). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • alpha-synuclein
  • synuclein, alpha (non A4 component of amyloid precursor)
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Properties