Protein Name RELB proto-oncogene, NF-kB subunit
Organism Homo sapiens
Gene ID 5971
Gene Symbol

RELB

UniProt Q01201 (RELB_HUMAN), D6R992 (D6R992_HUMAN)
Relationships Total Number of functionally related compound(s) : 91
Total Number of Articles : 97
Description

RELB proto-oncogene, NF-kB subunit

Gene Summary

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and protein kinase binding activity. Involved in lymphocyte differentiation and negative regulation of interferon-beta production. Located in cytosol and nucleoplasm. Part of chromatin; nucleus; and transcription repressor complex. Colocalizes with centrosome. Implicated in breast cancer and immunodeficiency 53. Biomarker of breast cancer and transitional cell carcinoma. [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • transcription factor RelB
  • v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
  • v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
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Properties