Protein Name | X-ray repair cross complementing 6 |
---|---|
Organism | Homo sapiens |
Gene ID | 2547 |
Gene Symbol | XRCC6 |
UniProt | P12956 (XRCC6_HUMAN), B1AHC9 (B1AHC9_HUMAN), A0A024R1N4 (A0A024R1N4_HUMAN), B4E356 (B4E356_HUMAN), B4DE32 (B4DE32_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
113
Total Number of Articles : 139 |
Description |
X-ray repair cross complementing 6 |
Gene Summary |
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008] |
synonyms |
|
Properties | |