Protein Name X-ray repair cross complementing 6
Organism Homo sapiens
Gene ID 2547
Gene Symbol


UniProt P12956 (XRCC6_HUMAN), B1AHC9 (B1AHC9_HUMAN), A0A024R1N4 (A0A024R1N4_HUMAN), B4E356 (B4E356_HUMAN), B4DE32 (B4DE32_HUMAN)
Relationships Total Number of functionally related compound(s) : 113
Total Number of Articles : 139

X-ray repair cross complementing 6

Gene Summary

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]

  • X-ray repair cross-complementing protein 6
  • 5'-dRP lyase Ku70
  • 5'-deoxyribose-5-phosphate lyase Ku70
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