Protein Name hepatocyte growth factor-regulated tyrosine kinase substrate
Organism Homo sapiens
Gene ID 9146
Gene Symbol

HGS

UniProt O14964 (HGS_HUMAN), A0A0S2Z4R4 (A0A0S2Z4R4_HUMAN)
Relationships Total Number of functionally related compound(s) : 53
Total Number of Articles : 41
Description

hepatocyte growth factor-regulated tyrosine kinase substrate

Gene Summary

The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation. [provided by RefSeq, Dec 2010]

synonyms
  • hepatocyte growth factor-regulated tyrosine kinase substrate
  • human growth factor-regulated tyrosine kinase substrate
  • protein pp110
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Properties