Protein Name solute carrier family 6 member 2
Organism Homo sapiens
Gene ID 6530
Gene Symbol


UniProt P23975 (SC6A2_HUMAN), H3BRE9 (H3BRE9_HUMAN), A0A024R6T9 (A0A024R6T9_HUMAN)
Relationships Total Number of functionally related compound(s) : 330
Total Number of Articles : 443

solute carrier family 6 member 2

Gene Summary

This gene encodes a member of the sodium:neurotransmitter symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic intolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]

  • sodium-dependent noradrenaline transporter
  • neurotransmitter transporter
  • norepinephrine transporter
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