Protein Name aspartoacylase
Organism Homo sapiens
Gene ID 443
Gene Symbol

ASPA

UniProt P45381 (ACY2_HUMAN), Q6FH48 (Q6FH48_HUMAN)
Relationships Total Number of functionally related compound(s) : 42
Total Number of Articles : 58
Description

aspartoacylase

Gene Summary

This gene encodes an enzyme that catalyzes the conversion of N-acetyl_L-aspartic acid (NAA) to aspartate and acetate. NAA is abundant in the brain where hydrolysis by aspartoacylase is thought to help maintain white matter. This protein is an NAA scavenger in other tissues. Mutations in this gene cause Canavan disease. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]

synonyms
  • aspartoacylase
  • ACY-2
  • aminoacylase 2
Click to show/hide the synonyms
Properties