Protein Name lanosterol synthase
Organism Homo sapiens
Gene ID 4047
Gene Symbol

LSS

UniProt P48449 (LSS_HUMAN), B2R694 (B2R694_HUMAN)
Relationships Total Number of functionally related compound(s) : 59
Total Number of Articles : 54
Description

lanosterol synthase

Gene Summary

The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Feb 2009]

synonyms
  • lanosterol synthase
  • 2,3-epoxysqualene-lanosterol cyclase
  • epididymis secretory sperm binding protein
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Properties