Protein Name glycogen synthase kinase 3 alpha
Organism Rattus norvegicus
Gene ID 50686
Gene Symbol

Gsk3a

UniProt P18265 (GSK3A_RAT)
Relationships Total Number of functionally related compound(s) : 302
Total Number of Articles : 346
Description

glycogen synthase kinase 3 alpha

Gene Summary

Enables protein kinase A catalytic subunit binding activity and protein serine/threonine kinase activity. Involved in several processes, including negative regulation of dendrite development; positive regulation of neuron apoptotic process; and protein phosphorylation. Located in cytoplasm and microtubule. Biomarker of Parkinsonism. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Orthologous to human GSK3A (glycogen synthase kinase 3 alpha). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • glycogen synthase kinase-3 alpha
  • FA
  • GSK-3 alpha
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Properties