Protein Name kallikrein related peptidase 8
Organism Homo sapiens
Gene ID 11202
Gene Symbol

KLK8

UniProt O60259 (KLK8_HUMAN), A0A0A0MQY9 (A0A0A0MQY9_HUMAN)
Relationships Total Number of functionally related compound(s) : 102
Total Number of Articles : 62
Description

kallikrein related peptidase 8

Gene Summary

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

synonyms
  • kallikrein-8
  • ovasin
  • serine protease 19
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Properties