Protein Name growth hormone secretagogue receptor
Organism Rattus norvegicus
Gene ID 84022
Gene Symbol

Ghsr

UniProt O08725 (GHSR_RAT)
Relationships Total Number of functionally related compound(s) : 109
Total Number of Articles : 135
Description

growth hormone secretagogue receptor

Gene Summary

Enables growth hormone secretagogue receptor activity and peptide hormone binding activity. Involved in several processes, including regulation of digestive system process; regulation of secretion by cell; and response to peptide hormone. Acts upstream of or within negative regulation of insulin secretion. Located in plasma membrane. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Is integral component of synaptic membrane. Used to study middle cerebral artery infarction. Biomarker of isolated growth hormone deficiency; multiple endocrine neoplasia; obstructive sleep apnea; status epilepticus; and transient cerebral ischemia. Human ortholog(s) of this gene implicated in obesity. Orthologous to human GHSR (growth hormone secretagogue receptor). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • growth hormone secretagogue receptor type 1
  • GH-releasing peptide receptor
  • GHRP
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Properties