Protein Name cholecystokinin B receptor
Organism Homo sapiens
Gene ID 887
Gene Symbol

CCKBR

UniProt P32239 (GASR_HUMAN), E9PIC8 (E9PIC8_HUMAN)
Relationships Total Number of functionally related compound(s) : 299
Total Number of Articles : 352
Description

cholecystokinin B receptor

Gene Summary

This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. Alternative splicing results in multiple transcript variants. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. [provided by RefSeq, Dec 2015]

synonyms
  • gastrin/cholecystokinin type B receptor
  • CCK-B receptor
  • CCK2 receptor
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Properties