CPRiL

TRIM27

tripartite motif containing 27

This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nuclear matrix. It interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in the differentiation of male germ cells. Fusion of the N-terminus of this protein with the truncated C-terminus of the RET gene product has been shown to result in production of the ret transforming protein. [provided by RefSeq, Jul 2008]

• zinc finger protein RFP
• RFP transforming protein
• RING finger protein 76
RING-type E3 ubiquitin transferase TRIM27
ret finger protein
tripartite motif protein TRIM27
tripartite motif-containing protein 27
RFP
RNF76