Protein Name 5', 3'-nucleotidase, cytosolic
Organism Homo sapiens
Gene ID 30833
Gene Symbol

NT5C

UniProt Q8TCD5 (NT5C_HUMAN), V9HWF3 (V9HWF3_HUMAN)
Relationships Total Number of functionally related compound(s) : 124
Total Number of Articles : 99
Description

5', 3'-nucleotidase, cytosolic

Gene Summary

This gene encodes a nucleotidase that catalyzes the dephosphorylation of the 5' deoxyribonucleotides (dNTP) and 2'(3')-dNTP and ribonucleotides, but not 5' ribonucleotides. Of the different forms of nucleotidases characterized, this enzyme is unique in its preference for 5'-dNTP. It may be one of the enzymes involved in regulating the size of dNTP pools in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011]

synonyms
  • 5'(3')-deoxyribonucleotidase, cytosolic type
  • 5' nucleotidase, deoxy (pyrimidine), cytosolic type C
  • cytosolic 5',3'-pyrimidine nucleotidase
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Properties