| Protein Name | membrane metallo-endopeptidase |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 24590 |
| Gene Symbol | Mme |
| UniProt | P07861 (NEP_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
315
Total Number of Articles : 390 |
Description |
membrane metallo-endopeptidase |
| Gene Summary |
Enables oligopeptidase activity and peptide binding activity. Involved in several processes, including amyloid-beta clearance by cellular catabolic process; animal organ development; and proteolysis. Located in plasma membrane. Used to study diarrhea and hypertension. Biomarker of Alzheimer's disease; congestive heart failure; and hepatocellular carcinoma. Human ortholog(s) of this gene implicated in Alzheimer's disease; Charcot-Marie-Tooth disease axonal type 2T; cerebellar ataxia type 43; cerebral amyloid angiopathy; and membranous glomerulonephritis. Orthologous to human MME (membrane metalloendopeptidase). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |