Protein Name growth hormone releasing hormone receptor
Organism Rattus norvegicus
Gene ID 25321
Gene Symbol

Ghrhr

UniProt Q02644 (GHRHR_RAT)
Relationships Total Number of functionally related compound(s) : 39
Total Number of Articles : 38
Description

growth hormone releasing hormone receptor

Gene Summary

Enables growth hormone-releasing hormone receptor activity. Involved in several processes, including activation of adenylate cyclase activity; cAMP/PKA signal transduction; and positive regulation of circadian sleep/wake cycle, non-REM sleep. Located in cell surface and sarcolemma. Used to study isolated growth hormone deficiency. Biomarker of sleep disorder. Human ortholog(s) of this gene implicated in isolated growth hormone deficiency and isolated growth hormone deficiency type IB. Orthologous to human GHRHR (growth hormone releasing hormone receptor). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • growth hormone-releasing hormone receptor
  • GHRH receptor
  • GRF receptor
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Properties