Protein Name BAG cochaperone 1
Organism Homo sapiens
Gene ID 573
Gene Symbol

BAG1

UniProt Q99933 (BAG1_HUMAN)
Relationships Total Number of functionally related compound(s) : 161
Total Number of Articles : 150
Description

BAG cochaperone 1

Gene Summary

The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X. [provided by RefSeq, Feb 2010]

synonyms
  • BAG family molecular chaperone regulator 1
  • BCL2 associated athanogene 1
  • BCL2-associated athanogene
Click to show/hide the synonyms
Properties