Protein Name galectin 3
Organism Rattus norvegicus
Gene ID 83781
Gene Symbol

Lgals3

UniProt P08699 (LEG3_RAT)
Relationships Total Number of functionally related compound(s) : 102
Total Number of Articles : 96
Description

galectin 3

Gene Summary

Enables several functions, including Fc-gamma receptor I complex binding activity; IgE binding activity; and advanced glycation end-product receptor activity. Involved in several processes, including negative regulation of cell proliferation in bone marrow; positive regulation of serotonin secretion; and response to quercetin. Located in cell surface; extracellular matrix; and extracellular space. Biomarker of several diseases, including acute kidney failure; attention deficit hyperactivity disorder; brain ischemia; colon cancer; and congestive heart failure. Human ortholog(s) of this gene implicated in asthma. Orthologous to human LGALS3 (galectin 3). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • galectin-3
  • 35 kDa lectin
  • CBP 35
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Properties