PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
35569132-6	2022	Moreover, silencing the ethylene synthesis genes, SlACS1A, SlACS1B, SlACO1, and SlACO4, resulted in a significant decrease in cold tolerance.	ethylene	24-32	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	68-74
33384413-5	2021	The expression levels of key ethylene biosynthesis genes (SlACS2, SlACS4, SlACO1, and SlACO3) and crucial ripening regulators (RIN and NOR) were increased in SlGRAS4-OE fruit.	ethylene	29-37	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	74-80
3029690-4	1987	Following mechanical wounding of tomato leaves a pTOM 13--homologous RNA shows rapid induction within 30 minutes, which occurs before maximal ethylene evolution (2-3 h).	ethylene	142-150	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	49-56
29978907-8	2018	SlREM1 can interact with ethylene biosynthesis proteins SAM1, ACO1 and ACS2 and is degraded by ubiquitin-mediated proteolysis.	ethylene	25-33	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	62-66
31229781-7	2019	Moreover, the ethylene biosynthesis genes (ACO1, ACO3, and ACS2) and ethylene inducible genes (E4 and E8), which participate in tomato fruit ripening, were suppressed.	ethylene	14-22	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	43-47
30583368-4	2019	5 muL L-1 1-MCP prefumigation decreased the expression of ethylene biosynthesis and perception related genes SlACO1, SlACS2, SlERF1, SlPti5 and SlMPK3, and ethylene production in C. laurentii treated fruit.	ethylene	58-66	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	109-115
30348324-7	2018	Transient over-expression of SlAREB1 in tomato fruits results in elevated expression of NOR as well as a number of downstream ethylene biosynthetic genes including SlACS2, SlACS4 and SlACO1, suggesting that SlAREB1 can mediate ABA signal to activate NOR transcription and ultimately promote ethylene synthesis.	Abscisic Acid	227-230	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	183-189
30348324-7	2018	Transient over-expression of SlAREB1 in tomato fruits results in elevated expression of NOR as well as a number of downstream ethylene biosynthetic genes including SlACS2, SlACS4 and SlACO1, suggesting that SlAREB1 can mediate ABA signal to activate NOR transcription and ultimately promote ethylene synthesis.	ethylene	291-299	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	183-189
30386366-8	2018	A modified biotin-switch method (MBST) showed that H2S can induce persulfidation of LeACO1 and LeACO2 in a dose-dependent manner, and that persulfidation inhibits the activity of LeACO1 and LeACO2.	Biotin	11-17	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	84-90
30386366-8	2018	A modified biotin-switch method (MBST) showed that H2S can induce persulfidation of LeACO1 and LeACO2 in a dose-dependent manner, and that persulfidation inhibits the activity of LeACO1 and LeACO2.	Biotin	11-17	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	179-185
30386366-8	2018	A modified biotin-switch method (MBST) showed that H2S can induce persulfidation of LeACO1 and LeACO2 in a dose-dependent manner, and that persulfidation inhibits the activity of LeACO1 and LeACO2.	Hydrogen Sulfide	51-54	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	84-90
30386366-8	2018	A modified biotin-switch method (MBST) showed that H2S can induce persulfidation of LeACO1 and LeACO2 in a dose-dependent manner, and that persulfidation inhibits the activity of LeACO1 and LeACO2.	Hydrogen Sulfide	51-54	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	179-185
30386366-9	2018	We also found that LeACO1 is persulfidated at cysteine 60.	Cysteine	46-54	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	19-25
33016583-11	2019	In transgenic tomato, PpEIIN3 showed overexpression and the key ethylene biosynthesis genes SlACO1, SlACS1, and SlSAMS1 were upregulated and promoted early maturation in fruit.	ethylene	64-72	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	92-98
30150109-6	2018	Analyses of the transcription levels of the ethylene biosynthesis genes ACC synthase (ACS) and ACC oxidase (ACO) in nor plants revealed that the induced ethylene production was largely due to transcriptional accumulation of ACS2 and ACO1.	ethylene	44-52	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	233-237
30150109-6	2018	Analyses of the transcription levels of the ethylene biosynthesis genes ACC synthase (ACS) and ACC oxidase (ACO) in nor plants revealed that the induced ethylene production was largely due to transcriptional accumulation of ACS2 and ACO1.	ethylene	153-161	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	233-237
28649000-10	2017	Besides, the expression of ethylene-related genes, including ACO1, ACO3, ACS2, ERF1, E4 and E8, was simultaneously up-regulated in transgenic plants.	ethylene	27-35	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	61-65
28932910-8	2018	Climacteric ethylene production also stimulated along with significantly up-regulated expression of ethylene biosynthetic genes (ACS2, ACS4, ACO1 and ACO3) and fruit ripening-associated genes (RIN, E4, E8, PG, Pti4, LOXB, Cnr and TAGL1) in SlHDA3 RNAi lines.	ethylene	12-20	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	141-145
26852223-6	2016	The silencing of SNAC4 and SNAC9 dramatically repressed the LeACS2, LeACS4 and LeACO1 expression, which consequently led to the inhibition of the ripening process.	snac9	27-32	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	79-85
28798762-6	2017	The expression of two ethylene inducible genes (E4 and E8) and three ethylene biosynthesis genes (SlACO1, SlACO3 and SlACS2) increased to a higher level in SlSAHH2 over-expression lines at breaker stage, and one transgenic line even produced much more ethylene than wild-type.	ethylene	69-77	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	98-104
28798762-6	2017	The expression of two ethylene inducible genes (E4 and E8) and three ethylene biosynthesis genes (SlACO1, SlACO3 and SlACS2) increased to a higher level in SlSAHH2 over-expression lines at breaker stage, and one transgenic line even produced much more ethylene than wild-type.	ethylene	69-77	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	98-104
28025888-4	2017	Overexpression of XTH2 and XTH10 in tomato resulted in the elevated expression of genes involved in ethylene biosynthesis (ACS2, ACO1), signal transduction (ERF2), and fruit softening (XTHs, PG2A, Cel2, and TBG4).	ethylene	100-108	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	129-133
28408916-4	2017	We examined the expression of two tomato ACO genes, LeACO1, and LeACO4 that encode the last enzyme in ethylene biosynthesis, 1-aminocyclopropane-1-carboxylate oxidase (ACO), together with the expression of other abscission-associated genes involved in cell separation and programmed cell death, during a period of 0-12 h after abscission induction in the tomato flower pedicel abscission zone and nearby tissues.	ethylene	102-110	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	52-58
26852223-6	2016	The silencing of SNAC4 and SNAC9 dramatically repressed the LeACS2, LeACS4 and LeACO1 expression, which consequently led to the inhibition of the ripening process.	snac4	17-22	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	79-85
27100326-3	2016	Combined RNA-seq with time-course RT-PCR analysis, our study not only helped to illustrate how ABA regulated itself at the transcription level, but also revealed that ABA can facilitate ethylene production and response probably by regulating some crucial genes such as LeACS4, LeACO1, GR and LeETR6.	alisol B 23-acetate	95-98	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	277-283
27100326-3	2016	Combined RNA-seq with time-course RT-PCR analysis, our study not only helped to illustrate how ABA regulated itself at the transcription level, but also revealed that ABA can facilitate ethylene production and response probably by regulating some crucial genes such as LeACS4, LeACO1, GR and LeETR6.	alisol B 23-acetate	167-170	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	277-283
27100326-3	2016	Combined RNA-seq with time-course RT-PCR analysis, our study not only helped to illustrate how ABA regulated itself at the transcription level, but also revealed that ABA can facilitate ethylene production and response probably by regulating some crucial genes such as LeACS4, LeACO1, GR and LeETR6.	ethylene	186-194	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	277-283
26748512-5	2016	Ethylene synthesis genes LeACS2 and LeACO1 were rapidly up-regulated, and the phosphorylated LeACS2 protein was detected after OGs treatment.	ethylene	0-8	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	36-42
21520447-5	2011	Exogenous ethylene could positively affect gene expression of mature green AC tomato fruit compared with the control, including LE-ACS2, LE-ACO1 and LE-ACO4.	ethylene	10-18	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	137-144
22919320-6	2012	Results showed that transgenic lines harboring the hpRNA-ACO1 construct had lower ethylene production and a longer shelf life of 32 days as compared to 10 days for wild-type fruits.	ethylene	82-90	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	57-61
26492077-5	2015	Gene expression analysis using ABA deficient mutants sit and flc as well as the SlZFP2 RNAi lines of high fruit ABA production showed that ethylene biosynthetic genes LeACS1A, LeACS1 and LeACO1 were positively regulated by ABA during early fruit growth.	ethylene	139-147	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	187-193
24751940-9	2014	Besides, both ethylene-dependent genes including ACS2, ACO1, E4 and E8 and ethylene-independent genes such as HDC and Nor were also up-regulated in transgenic fruits at different levels.	ethylene	14-22	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	55-59
21520447-4	2011	RESULTS: RIN transcription factor generates strong or weak induction of the expression of LE-ACS2, LE-ACS4 and LE-ACO1 associated with ethylene biosynthesis.	ethylene	135-143	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	111-118
21520447-8	2011	CONCLUSION: RIN transcription factor has an impact upon ethylene biosynthesis via regulating transcription of LE-ACS2, LE-ACS4, LE-ACO1 and LE-ACS6.	ethylene	56-64	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	128-135
16786314-9	2006	Experiments with LEACO1(0.821) (kb)-gus transgenic tobacco plants suggested auxin and ethylene involvement in induction of LEACO1(0.821) (kb) promoter activity.	Indoleacetic Acids	76-81	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	17-23
18346193-7	2008	Expression of the ethylene-responsive genes E4 and chitinase B was upregulated in transgenic plants, but ethylene production and the level of mRNA for the ethylene biosynthetic gene ACO1 was unaffected.	ethylene	18-26	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	182-186
21170714-7	2011	Ether strongly induced ACO4 and moderately induced ACO1, whereas mechanical wounding strongly induced ACO1 and slightly induced ACO4.	Ether	0-5	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	51-55
16786314-9	2006	Experiments with LEACO1(0.821) (kb)-gus transgenic tobacco plants suggested auxin and ethylene involvement in induction of LEACO1(0.821) (kb) promoter activity.	Indoleacetic Acids	76-81	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	123-129
16786314-9	2006	Experiments with LEACO1(0.821) (kb)-gus transgenic tobacco plants suggested auxin and ethylene involvement in induction of LEACO1(0.821) (kb) promoter activity.	ethylene	86-94	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	17-23
16786314-9	2006	Experiments with LEACO1(0.821) (kb)-gus transgenic tobacco plants suggested auxin and ethylene involvement in induction of LEACO1(0.821) (kb) promoter activity.	ethylene	86-94	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	123-129
16786314-10	2006	Multiple copies of nucleotide base sequences associated with either ethylene or auxin response elements were identified in the LEACO1(0.821) (kb) promoter fragment.	ethylene	68-76	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	127-133
12481074-4	2002	In transgenic plants containing an LE-ACO1 promoter-beta-glucuronidase fusion construct, beta-glucuronidase activity increased rapidly at the beginning of the O(3) exposure and had a spatial distribution resembling the pattern of extracellular H(2)O(2) production at 7 h, which coincided with the cell death pattern after 24 h. Ethylene synthesis and perception were required for active H(2)O(2) production and cell death resulting in visible tissue damage.	Ozone	159-163	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	35-42
15310826-12	2004	In response to PRD, ACO1AS and wild-type plants showed similar xylem sap pH, [X-ABA] and gs, but ACO1AS plants showed neither enhanced ethylene evolution nor significant reductions in leaf elongation.	x-aba	78-83	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	20-24
14551334-5	2003	Biochemical analysis of leaves of the Aco-1 accession suggested that they exhibited a restricted flux through the Krebs cycle and reduced levels of Krebs cycle intermediates but were characterized by elevated adenylate levels and an enhanced rate of CO2 assimilation.	krebs	114-119	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	38-43
14551334-5	2003	Biochemical analysis of leaves of the Aco-1 accession suggested that they exhibited a restricted flux through the Krebs cycle and reduced levels of Krebs cycle intermediates but were characterized by elevated adenylate levels and an enhanced rate of CO2 assimilation.	krebs	148-153	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	38-43
14551334-5	2003	Biochemical analysis of leaves of the Aco-1 accession suggested that they exhibited a restricted flux through the Krebs cycle and reduced levels of Krebs cycle intermediates but were characterized by elevated adenylate levels and an enhanced rate of CO2 assimilation.	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	250-253	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	38-43
16167902-7	2005	We found that AvrPto and AvrPtoB induce a set of host genes involved in ethylene biosynthesis and signaling, and in particular they regulate the expression of two genes, LeACO1 and LeACO2, encoding the ethylene-forming enzyme ACC oxidase.	ethylene	72-80	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	170-176
12481074-4	2002	In transgenic plants containing an LE-ACO1 promoter-beta-glucuronidase fusion construct, beta-glucuronidase activity increased rapidly at the beginning of the O(3) exposure and had a spatial distribution resembling the pattern of extracellular H(2)O(2) production at 7 h, which coincided with the cell death pattern after 24 h. Ethylene synthesis and perception were required for active H(2)O(2) production and cell death resulting in visible tissue damage.	Hydrogen Peroxide	244-252	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	35-42
12481074-4	2002	In transgenic plants containing an LE-ACO1 promoter-beta-glucuronidase fusion construct, beta-glucuronidase activity increased rapidly at the beginning of the O(3) exposure and had a spatial distribution resembling the pattern of extracellular H(2)O(2) production at 7 h, which coincided with the cell death pattern after 24 h. Ethylene synthesis and perception were required for active H(2)O(2) production and cell death resulting in visible tissue damage.	ethylene	328-336	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	35-42
12481074-4	2002	In transgenic plants containing an LE-ACO1 promoter-beta-glucuronidase fusion construct, beta-glucuronidase activity increased rapidly at the beginning of the O(3) exposure and had a spatial distribution resembling the pattern of extracellular H(2)O(2) production at 7 h, which coincided with the cell death pattern after 24 h. Ethylene synthesis and perception were required for active H(2)O(2) production and cell death resulting in visible tissue damage.	Hydrogen Peroxide	387-395	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	35-42
12172802-1	2002	Gene silencing by an ACO1 [1-aminocyclopropane-1-carboxylate (ACC) oxidase 1] sense transgene in tomato plants was correlated with the production of small antisense RNAs (asRNAs) of 21-28 nucleotides, which were preferentially generated from the 3" region of the transgene.	-aminocyclopropane-1-carboxylate	28-60	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	21-25
10594109-8	1999	These genotypic differences in growth were accompanied by increased ethylene evolution in cv Ailsa Craig, suggesting that the ability of ACO1(AS) to maintain growth in the split-pot treatment reflected its lower ethylene levels, a view supported by the observation that excising the roots in the compacted compartment reduced ethylene evolution and restored shoot growth in cv Ailsa Craig.	ethylene	68-76	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	137-141
10889245-6	2000	In contrast, the induction of the 1-aminocyclopropane-1-carboxylic acid oxidases, LEACO1 and LEACO3, following pollination is ethylene dependent.	ethylene	126-134	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	82-88
10594109-8	1999	These genotypic differences in growth were accompanied by increased ethylene evolution in cv Ailsa Craig, suggesting that the ability of ACO1(AS) to maintain growth in the split-pot treatment reflected its lower ethylene levels, a view supported by the observation that excising the roots in the compacted compartment reduced ethylene evolution and restored shoot growth in cv Ailsa Craig.	ethylene	212-220	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	137-141
10594109-8	1999	These genotypic differences in growth were accompanied by increased ethylene evolution in cv Ailsa Craig, suggesting that the ability of ACO1(AS) to maintain growth in the split-pot treatment reflected its lower ethylene levels, a view supported by the observation that excising the roots in the compacted compartment reduced ethylene evolution and restored shoot growth in cv Ailsa Craig.	ethylene	212-220	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	137-141
1714605-1	1991	The ethylene-forming enzyme (EFE), which catalyzes the last step in the biosynthesis of the plant hormone ethylene, has never been purified and no molecular probes are available.	ethylene	4-12	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	29-32
9847103-9	1998	The results suggest that in tomato fruit the preclimacteric system 1 ethylene is possibly mediated via constitutively expressed LE-ACS1A and LE-ACS3 and negatively feedback-regulated LE-ACS6 genes with preexisting LE-ACO1 and LE-ACO4 mRNAs.	ethylene	69-77	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	214-221
16652987-4	1992	Pch313 was sequenced and found to be related to a tomato fruit cDNA clone, pTOM13, which has been shown to encode the ethylene-forming enzyme.	ethylene	118-126	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	75-81
16652987-5	1992	The derived amino acid sequence of pch313 is 74 to 83% identical to the pTOM13-related sequences.	pch313	35-41	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	72-78
9578456-1	1998	Heterologous expression in yeast has previously shown that the tomato cDNA LE-ACO1 encodes a functional 1-aminocyclopropane-1-carboxylate (ACC) oxidase (ACO) protein [Hamilton, A. J., Bouzayen, M. & Grierson, D. (1991) Proc.	1-aminocyclopropane-1-carboxylic acid	104-137	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	78-82
9375389-1	1997	The enzyme ACC oxidase, catalysing the last step in the biosynthesis of the plant hormone ethylene, is encoded by a small multigene family in tomato, comprising three members, LEACO1, LEACO2 and LEACO3.	ethylene	90-98	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	176-182
9375389-6	1997	Fusion of 396 and 1825 bp of LEACO1 upstream sequence resulted in strong and specific induction of GUS expression in situations known to be accompanied by enhanced ethylene production.	ethylene	164-172	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	29-35
12228680-2	1995	Petioles of flooded plants transformed with an antisense construct to one isoform of an ACC oxidase gene (ACO1) produced less ethylene and had lower ACC oxidase activity than those of the wild type.	ethylene	126-134	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	106-110
7764617-1	1994	The subcellular localization of 1-aminocyclopropane-1-carboxylic acid oxidase (ACC oxidase), an enzyme involved in the biosynthesis of ethylene, has been studied in ripening fruits of tomato (Lycopersicum esculentum Mill.).	ethylene	135-143	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	32-77
7764617-1	1994	The subcellular localization of 1-aminocyclopropane-1-carboxylic acid oxidase (ACC oxidase), an enzyme involved in the biosynthesis of ethylene, has been studied in ripening fruits of tomato (Lycopersicum esculentum Mill.).	ethylene	135-143	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	79-90
1714605-1	1991	The ethylene-forming enzyme (EFE), which catalyzes the last step in the biosynthesis of the plant hormone ethylene, has never been purified and no molecular probes are available.	ethylene	106-114	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	29-32
1714605-2	1991	Recently, a putative cDNA clone for tomato EFE (pTOM13) has been identified by inhibiting ethylene synthesis with an antisense gene expressed in transgenic plants.	ethylene	90-98	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	43-46
1714605-2	1991	Recently, a putative cDNA clone for tomato EFE (pTOM13) has been identified by inhibiting ethylene synthesis with an antisense gene expressed in transgenic plants.	ethylene	90-98	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	48-54
1714605-6	1991	This EFE activity displays similar characteristics to EFE found in plant tissue: it converts the trans isomer of the ACC analogue 1-amino-2-ethylcyclopropane-1-carboxylic acid to 1-butene in preference to the cis isomer, and it is strongly inhibited by cobaltous ions and 1,10-phenanthroline.	1-amino-2-ethylcyclopropane-1-carboxylic acid	130-175	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	5-8
1714605-6	1991	This EFE activity displays similar characteristics to EFE found in plant tissue: it converts the trans isomer of the ACC analogue 1-amino-2-ethylcyclopropane-1-carboxylic acid to 1-butene in preference to the cis isomer, and it is strongly inhibited by cobaltous ions and 1,10-phenanthroline.	1-amino-2-ethylcyclopropane-1-carboxylic acid	130-175	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	54-57
1714605-6	1991	This EFE activity displays similar characteristics to EFE found in plant tissue: it converts the trans isomer of the ACC analogue 1-amino-2-ethylcyclopropane-1-carboxylic acid to 1-butene in preference to the cis isomer, and it is strongly inhibited by cobaltous ions and 1,10-phenanthroline.	1-butene	179-187	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	5-8
1714605-6	1991	This EFE activity displays similar characteristics to EFE found in plant tissue: it converts the trans isomer of the ACC analogue 1-amino-2-ethylcyclopropane-1-carboxylic acid to 1-butene in preference to the cis isomer, and it is strongly inhibited by cobaltous ions and 1,10-phenanthroline.	1-butene	179-187	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	54-57
1714605-6	1991	This EFE activity displays similar characteristics to EFE found in plant tissue: it converts the trans isomer of the ACC analogue 1-amino-2-ethylcyclopropane-1-carboxylic acid to 1-butene in preference to the cis isomer, and it is strongly inhibited by cobaltous ions and 1,10-phenanthroline.	cobaltous	253-262	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	5-8
1714605-6	1991	This EFE activity displays similar characteristics to EFE found in plant tissue: it converts the trans isomer of the ACC analogue 1-amino-2-ethylcyclopropane-1-carboxylic acid to 1-butene in preference to the cis isomer, and it is strongly inhibited by cobaltous ions and 1,10-phenanthroline.	cobaltous	253-262	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	54-57
1714605-6	1991	This EFE activity displays similar characteristics to EFE found in plant tissue: it converts the trans isomer of the ACC analogue 1-amino-2-ethylcyclopropane-1-carboxylic acid to 1-butene in preference to the cis isomer, and it is strongly inhibited by cobaltous ions and 1,10-phenanthroline.	1,10-phenanthroline	272-291	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	5-8
1714605-6	1991	This EFE activity displays similar characteristics to EFE found in plant tissue: it converts the trans isomer of the ACC analogue 1-amino-2-ethylcyclopropane-1-carboxylic acid to 1-butene in preference to the cis isomer, and it is strongly inhibited by cobaltous ions and 1,10-phenanthroline.	1,10-phenanthroline	272-291	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	54-57
1868215-0	1991	eth1, a gene involved in ethylene synthesis in tomato.	ethylene	25-33	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	0-4
2065651-6	1991	Hybridization and co-injection experiments demonstrate that the tomato RNA species directing EFE expression in oocytes are homologous to clone pTOM13 which has been shown to inhibit ethylene production in plants when expressed in antisense.	ethylene	182-190	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	143-149
34369570-3	2021	We characterized two related proteins with contrasting impact on ethylene production, ACC oxidase 1 (SlACO1) and SlE8.	ethylene	65-73	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	86-99
29223340-6	2017	Ethylene content was also reduced and expression of ethylene biosynthetic genes (ACS2, ACS4 and ACO1, ACO3) and ripening-associated genes (RIN, E4, E8, PG, Pti4 and LOXB) was significantly down-regulated in SlHDT3 RNAi lines.	ethylene	0-8	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	96-100
29223340-6	2017	Ethylene content was also reduced and expression of ethylene biosynthetic genes (ACS2, ACS4 and ACO1, ACO3) and ripening-associated genes (RIN, E4, E8, PG, Pti4 and LOXB) was significantly down-regulated in SlHDT3 RNAi lines.	ethylene	52-60	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	96-100
2033047-7	1991	With computer-aided comparison to other proteins we found that the hydroxylase is homologous to two synthases involved in the biosynthesis of beta-lactam antibiotics in some microorganisms and the gene products of tomato pTOM13 cDNA and maize A2 locus which had been proposed to catalyze oxidative reactions in the biosynthesis of ethylene and anthocyan, respectively.	beta-Lactams	142-153	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	221-227
2033047-7	1991	With computer-aided comparison to other proteins we found that the hydroxylase is homologous to two synthases involved in the biosynthesis of beta-lactam antibiotics in some microorganisms and the gene products of tomato pTOM13 cDNA and maize A2 locus which had been proposed to catalyze oxidative reactions in the biosynthesis of ethylene and anthocyan, respectively.	ethylene	331-339	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	221-227
34369570-3	2021	We characterized two related proteins with contrasting impact on ethylene production, ACC oxidase 1 (SlACO1) and SlE8.	ethylene	65-73	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	101-107
34369570-10	2021	This study highlights further the importance of SlACO1 and SlE8 in ethylene production in tomato fruit and how they might be used for post-harvest fruit preservation or speeding up fruit maturation.	ethylene	67-75	1-aminocyclopropane-1-carboxylate oxidase 1	Solanum lycopersicum	48-54