PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 34945637-0 2021 Dietary Curcumin Alleviated Aflatoxin B1-Induced Acute Liver Damage in Ducks by Regulating NLRP3-Caspase-1 Signaling Pathways. Curcumin 8-16 caspase-1 Anas platyrhynchos 97-106 34945637-0 2021 Dietary Curcumin Alleviated Aflatoxin B1-Induced Acute Liver Damage in Ducks by Regulating NLRP3-Caspase-1 Signaling Pathways. Aflatoxin B1 28-40 caspase-1 Anas platyrhynchos 97-106 34945637-6 2021 Dietary curcumin significantly inhibited the generation of H2O2 and MDA in liver, activated the Nrf2-ARE signaling pathway, and suppressed the NLRP3-caspase-1 signaling pathway in the liver of ducks. Curcumin 8-16 caspase-1 Anas platyrhynchos 149-158 34945637-7 2021 Conclusively, curcumin in diet could protect duck liver against the generation of AFB1-DNA adducts, toxicity, oxidation stress and inflammatory response induced by AFB1 through regulating the NLRP3-caspase-1 signaling pathways, demonstrating that curcumin is a potential feed additive agent to reduce the serious harmful effects of AFB1 on duck breeding. Curcumin 14-22 caspase-1 Anas platyrhynchos 198-207 34479002-7 2021 Taken together, the results illustrate that Mo and Cd might synergistically lead to oxidative stress and induce pyroptosis via NLRP3/Caspase-1 pathway, whose mechanism is somehow related to Mo and Cd accumulation in duck kidneys. Cadmium 51-53 caspase-1 Anas platyrhynchos 133-142 34729831-9 2021 Dietary resveratrol suppressed the TLR4/NF-kappaB signalling pathway and the expression of its downstream genes including IKK, TXNIP, NLRP3, Caspase-1, IL-6 and IL-18. Resveratrol 8-19 caspase-1 Anas platyrhynchos 141-150 34479002-7 2021 Taken together, the results illustrate that Mo and Cd might synergistically lead to oxidative stress and induce pyroptosis via NLRP3/Caspase-1 pathway, whose mechanism is somehow related to Mo and Cd accumulation in duck kidneys. Cadmium 197-199 caspase-1 Anas platyrhynchos 133-142 34614430-10 2021 Meanwhile, supplement resveratrol further inhibited the NLRP3 inflammasome pathway, decreased protein level of NLRP3 and caspase1 p20, reduced the secretion of IL-1beta. Resveratrol 22-33 caspase-1 Anas platyrhynchos 121-129 34479002-0 2021 In vivo assessment of molybdenum and cadmium co-induce nephrotoxicity via NLRP3/Caspase-1-mediated pyroptosis in ducks. Molybdenum 22-32 caspase-1 Anas platyrhynchos 80-89 34479002-0 2021 In vivo assessment of molybdenum and cadmium co-induce nephrotoxicity via NLRP3/Caspase-1-mediated pyroptosis in ducks. Cadmium 37-44 caspase-1 Anas platyrhynchos 80-89