PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 31425165-12 2019 Among children born small for gestational age, awake SBP z-scores had significant positive correlations with pre- and post-stress urinary dopamine levels (r = 0.530, P = 0.02 and r = 0.597, P = 0.007, respectively). Dopamine 138-146 selenium binding protein 1 Homo sapiens 53-56 31490245-9 2019 The invasive/oscillometric mean arterial pressures and SBP differences were +0.1 +- 3.4 and 7.6 +- 1.6 mmHg in patients treated with nothing or a maximum norepinephrine dose of 0.6 microg/kg/min. Norepinephrine 154-168 selenium binding protein 1 Homo sapiens 55-58 31490245-10 2019 However, treatment with very high doses of norepinephrine was associated with a steep rise in mean arterial pressures and SBP invasive/oscillometric differences (-9.5 +- 3.3 and -8.5 +- 5.2 mmHg). Norepinephrine 43-57 selenium binding protein 1 Homo sapiens 122-125 31331588-4 2019 Eligible RCTs were included if they investigate the effects of policosanol supplementation on systolic (SBP) and diastolic (DBP) blood pressure. policosanol 63-74 selenium binding protein 1 Homo sapiens 104-107 31481697-2 2019 We aimed to assess the effects of L-carnitine supplementation on systolic (SBP) and diastolic blood pressure (DBP). Carnitine 34-45 selenium binding protein 1 Homo sapiens 75-78 31481697-4 2019 A meta-analysis was conducted on a total of ten eligible randomized controlled trials using a random-effects model to estimate the pooled effect sizes of L-carnitine supplementation on SBP and DBP levels. Carnitine 154-165 selenium binding protein 1 Homo sapiens 185-188 31260905-4 2019 Especially, we utilized an easily accessible capturing approach based on silica binding peptide (SBP) for direct immobilization of PAS1 on the SiO2 surfaces. pas1 131-135 selenium binding protein 1 Homo sapiens 97-100 31260905-4 2019 Especially, we utilized an easily accessible capturing approach based on silica binding peptide (SBP) for direct immobilization of PAS1 on the SiO2 surfaces. Silicon Dioxide 143-147 selenium binding protein 1 Homo sapiens 97-100 31500169-11 2019 Over the 10-years, subjects in the highest EPA tertile presented with +2.92 and +1.94 mmHg higher SBP and DBP, respectively, and with 1.46 higher odds of being hypertensive. Eicosapentaenoic Acid 43-46 selenium binding protein 1 Homo sapiens 98-101 31350809-7 2019 Urinary sodium was significantly associated with SBP (beta = 1.08, P = .018) after adjustment for potential confounders. Sodium 8-14 selenium binding protein 1 Homo sapiens 49-52 31331588-8 2019 decrease significantly after policosanol supplementation with significant heterogeneity among included studies (I2 = 78.5% and 78.9% for SBP and DBP respectively). policosanol 29-40 selenium binding protein 1 Homo sapiens 137-140 31331588-10 2019 CONCLUSION: Policosanol could lower SBP and DBP significantly; future long term studies are required to confirm these findings in the general population. policosanol 12-23 selenium binding protein 1 Homo sapiens 36-39 31175711-11 2019 Twenty-four-hour SBP dropped from 144 to 145 mm Hg vs 128 to 126 mm Hg with perindopril-amlodipine and perindopril-indapamide, respectively (P = 0.003 for both groups). Perindopril 76-87 selenium binding protein 1 Homo sapiens 17-20 31175711-11 2019 Twenty-four-hour SBP dropped from 144 to 145 mm Hg vs 128 to 126 mm Hg with perindopril-amlodipine and perindopril-indapamide, respectively (P = 0.003 for both groups). Amlodipine 88-98 selenium binding protein 1 Homo sapiens 17-20 31175711-11 2019 Twenty-four-hour SBP dropped from 144 to 145 mm Hg vs 128 to 126 mm Hg with perindopril-amlodipine and perindopril-indapamide, respectively (P = 0.003 for both groups). Perindopril 103-114 selenium binding protein 1 Homo sapiens 17-20 31175711-11 2019 Twenty-four-hour SBP dropped from 144 to 145 mm Hg vs 128 to 126 mm Hg with perindopril-amlodipine and perindopril-indapamide, respectively (P = 0.003 for both groups). Indapamide 115-125 selenium binding protein 1 Homo sapiens 17-20 31211019-6 2019 Deoxygenated haemoglobin ( HHb) in the pre-frontal cortex (FH), gastrocnemius (GN), left vastus lateralis (LVL) and the right vastus lateralis (RVL) muscles, systemic oxygen utilisation (VO2), systolic (SBP) and diastolic (DBP) blood pressure and physical activity enjoyment scale (PACES) were measured during the experiment conditions. Oxygen 2-8 selenium binding protein 1 Homo sapiens 203-206 31261612-4 2019 NO2 was positively associated with systolic and diastolic blood pressure (SBP and DBP), and inversely associated with the central retinal venular equivalent (CRVE) and mean baseline brachial artery diameter. Nitrogen Dioxide 0-3 selenium binding protein 1 Homo sapiens 74-77 31242675-9 2019 Male participants in the worst quintile of alcohol consumption showed an increase of 3.0 mmHg in SBP and 0.8 mmHg in DBP compared to those in the greatest quintile. Alcohols 43-50 selenium binding protein 1 Homo sapiens 97-100 31301656-10 2019 ACIVAbs IgG showed correlation with duration of diabetes (r=0.49, p=0.01), retinopathy (r=-0.20, p=0.04) and BMI (r=-0.24, p=0.05), HbA1c (r=0.21, p=0.04), SBP (r=0.16, p=0.05). acivabs 0-7 selenium binding protein 1 Homo sapiens 156-159 30830724-7 2019 Ertugliflozin significantly reduced FPG, BW and SBP. ertugliflozin 0-13 selenium binding protein 1 Homo sapiens 48-51 30830724-13 2019 CONCLUSIONS: Ertugliflozin significantly improved glycaemic control and reduced BW and SBP in Asian patients with T2DM. ertugliflozin 13-26 selenium binding protein 1 Homo sapiens 87-90 31026243-7 2019 A 4-year change in SBP was associated with baPWV progression, whereas a 12-year change in DBP was associated with baPWV progression. bapwv 43-48 selenium binding protein 1 Homo sapiens 19-22 31026243-8 2019 The increased progression of baPWV presented a linear trend when subgrouping all the participants according to SBP and DBP changes over 4 and 12 years, respectively. bapwv 29-34 selenium binding protein 1 Homo sapiens 111-114 30914176-9 2019 Nevertheless, an effect between groups was observed in favor of the CG at 12 months in some CVRFS: SBP, DBP, total cholesterol and triglycerides: 2.02 mmHg (95%CI: 0.43-3.61), 1.21 mmHg (95%CI: 0.20-2.24), 5.24 mg/dl (95%CI: 1.22-9.26) and 7.24 mg/dl (95%CI: 0.53-14.32). cg 68-70 selenium binding protein 1 Homo sapiens 99-102 31065758-10 2019 Significant decreases in SBP, DBP, and MAP occurred within one hour of initiation of nicardipine and were sustained through the majority of the 48-h evaluation period. Nicardipine 85-96 selenium binding protein 1 Homo sapiens 25-28 31142774-6 2019 Multivariate models showed the lower Mg levels (quartile 1) as a strong independent factor contributing to IMT-CC along with age, sex, SBP, HDL-C, and diuretic use. Magnesium 37-39 selenium binding protein 1 Homo sapiens 135-138 30964905-7 2019 Fimasartan reduced systolic and diastolic BP (SBP and DBP) in clinic from 144.1 +- 17.3 to 127.7 +- 12.9 mmHg and from 85.1 +- 10.4 to 76.8 +- 8.4 mmHg, respectively, (all p<0.0001) in 1 year. fimasartan 0-10 selenium binding protein 1 Homo sapiens 46-49 31088622-7 2019 Multiple regression analyses showed that BMI, DHA, smoking status, and smoking status*ALA interaction significantly predicted SBP (p < 0.0001, R2 = 0.44) and DBP (p < 0.0001, R2 = 0.33), while ethnicity had no effect. alpha-Linolenic Acid 86-89 selenium binding protein 1 Homo sapiens 126-129 30869906-5 2019 We develop a two-step cooperative model that accurately captures the kinetics of silica binding and provides insights into how SBP-SBP interactions, fused scaffold, and solution conditions modulate adsorption. Silicon Dioxide 81-87 selenium binding protein 1 Homo sapiens 127-130 30869906-5 2019 We develop a two-step cooperative model that accurately captures the kinetics of silica binding and provides insights into how SBP-SBP interactions, fused scaffold, and solution conditions modulate adsorption. Silicon Dioxide 81-87 selenium binding protein 1 Homo sapiens 131-134 30771749-10 2019 The bootstrapping mediation models indicated that miR-21-5p partially mediated the relationships between Cu level and SBP/DBP. Copper 105-107 selenium binding protein 1 Homo sapiens 118-121 30817465-6 2019 RESULTS: Clinic and 24-h ambulatory BP significantly reduced following IET by 12.4/6.2 and 11.8/5.6 mmHg in SBP/DBP, respectively (P < 0.001 for both), compared with the control. 1-(4-CYANO-PHENYL)-3-[2-(2,6-DICHLORO-PHENYL)-1-IMINO-ETHYL]-THIOUREA 71-74 selenium binding protein 1 Homo sapiens 108-111 30938496-8 2019 Moreover, baPWV was only positively correlated with age, hypertension and SBP and inversely correlated with SEVR and ED in multivariable regression model. bapwv 10-15 selenium binding protein 1 Homo sapiens 74-77 30234779-8 2019 During the period of spring-autumn, continuous NAO indices on the same day and a positive NAO on the same and on 2 previous days were negatively associated with the SBP value. 10-N-nonylacridinium orange 47-50 selenium binding protein 1 Homo sapiens 165-168 30881007-3 2019 Results: The mean differences between the devices and mercury readings for SBP and DBP were as follows: HEM-6232T, -0.4+-6.7 mmHg and 1.6+-5.4 mmHg, respectively; HEM-6181, -0.7+-6.2 mmHg and -0.7+-5.2 mmHg, respectively, satisfying the ANSI/AAMI/ISO protocol. Mercury 54-61 selenium binding protein 1 Homo sapiens 75-78 30647466-7 2019 The pooled findings indicated a significant reduction in systolic (SBP) (SMD = -0.87; 95% CI, -1.36, -0.38; P = 0.001; I2: 84.3) and diastolic blood pressure (DBP) (SMD = -0.85; 95% CI, -1.20, -0.51; P = 0.001; I2: 68.7) following melatonin supplementation in individuals with metabolic disorders. Melatonin 231-240 selenium binding protein 1 Homo sapiens 67-70 30985644-7 2019 Systolic/diastolic blood pressure (SBP/DBP) were reduced from 153.9 +- 12.6/84.6 +- 11.8 to 129.8 +- 14.2/73.7 +- 12.2 mm Hg by eplerenone therapy and from 152.2 +- 12.5/85.2 +- 10.9 to 133.8 +- 12.6/76.1 +- 8.6 mm Hg by trichlormethiazide therapy (all; P < .001). Eplerenone 128-138 selenium binding protein 1 Homo sapiens 35-38 30985644-7 2019 Systolic/diastolic blood pressure (SBP/DBP) were reduced from 153.9 +- 12.6/84.6 +- 11.8 to 129.8 +- 14.2/73.7 +- 12.2 mm Hg by eplerenone therapy and from 152.2 +- 12.5/85.2 +- 10.9 to 133.8 +- 12.6/76.1 +- 8.6 mm Hg by trichlormethiazide therapy (all; P < .001). Trichlormethiazide 221-239 selenium binding protein 1 Homo sapiens 35-38 30312953-6 2019 The HNBP group showed significant positive correlation between HEX, HEX A (pKat/mL) and SBP. 2,2',4,4',6,6'-Hexanitrobiphenyl 4-8 selenium binding protein 1 Homo sapiens 88-91 30312953-6 2019 The HNBP group showed significant positive correlation between HEX, HEX A (pKat/mL) and SBP. 1,2,3,4,5,6-hexabromocyclohexane 63-66 selenium binding protein 1 Homo sapiens 88-91 30660016-7 2019 Mean SBP SDS was 0.70 +- 0.81 and mean DBP SDS was 0.14 +- 0.78. sds 9-12 selenium binding protein 1 Homo sapiens 5-8 30660016-8 2019 SBP SDS was positively associated with very preterm birth (beta 0.53, p = .002), with child BMI SDS (beta 0.25, p = .035), and maternal BMI >= 25 kg/m2 at 12 years (beta 0.49, p = .003), and not with pre-pregnancy maternal BMI >= 25 kg/m2. sds 4-7 selenium binding protein 1 Homo sapiens 0-3 30660016-8 2019 SBP SDS was positively associated with very preterm birth (beta 0.53, p = .002), with child BMI SDS (beta 0.25, p = .035), and maternal BMI >= 25 kg/m2 at 12 years (beta 0.49, p = .003), and not with pre-pregnancy maternal BMI >= 25 kg/m2. sds 96-99 selenium binding protein 1 Homo sapiens 0-3 30647466-8 2019 In summary, the current meta-analysis demonstrated that melatonin supplementation significantly decreased SBP and DBP in patients with metabolic disorders. Melatonin 56-65 selenium binding protein 1 Homo sapiens 106-109 30234779-8 2019 During the period of spring-autumn, continuous NAO indices on the same day and a positive NAO on the same and on 2 previous days were negatively associated with the SBP value. 10-N-nonylacridinium orange 90-93 selenium binding protein 1 Homo sapiens 165-168 30234779-9 2019 A positive NAO was associated (P = 0.001) with a decrease in SBP by 1.7 mmHg in all participants, by 2.30 mmHg in physically active participants, and by 3.62 mmHg in the elderly, as compared with a negative NAO. 10-N-nonylacridinium orange 11-14 selenium binding protein 1 Homo sapiens 61-64 30234779-9 2019 A positive NAO was associated (P = 0.001) with a decrease in SBP by 1.7 mmHg in all participants, by 2.30 mmHg in physically active participants, and by 3.62 mmHg in the elderly, as compared with a negative NAO. 10-N-nonylacridinium orange 207-210 selenium binding protein 1 Homo sapiens 61-64 30234779-10 2019 CONCLUSION: These results provided new evidence that the NAO index may be affect the value of SBP and DBP in the elderly during the period of spring-autumn. 10-N-nonylacridinium orange 57-60 selenium binding protein 1 Homo sapiens 94-97 31031490-13 2019 Comparing SBP, DBP, and MAP between the two groups, there was a significant increase in nalbuphine group than fentanyl group postintubation and was statistically significant at all intervals of time. Nalbuphine 88-98 selenium binding protein 1 Homo sapiens 10-13 30732890-2 2019 As the selenium (Se) status is affected by inflammation and hypoxia, we hypothesized that SELENBP1 contributes to disease-specific Se metabolism. Selenium 7-15 selenium binding protein 1 Homo sapiens 90-98 30732890-2 2019 As the selenium (Se) status is affected by inflammation and hypoxia, we hypothesized that SELENBP1 contributes to disease-specific Se metabolism. Selenium 17-19 selenium binding protein 1 Homo sapiens 90-98 30732890-2 2019 As the selenium (Se) status is affected by inflammation and hypoxia, we hypothesized that SELENBP1 contributes to disease-specific Se metabolism. Selenium 131-133 selenium binding protein 1 Homo sapiens 90-98 30732890-10 2019 CONCLUSIONS: Until now, SELENBP1 was mainly considered as an intracellular protein involved in Se metabolism and redox control. Selenium 95-97 selenium binding protein 1 Homo sapiens 24-32 31349945-10 2019 Co-Q10 and vitamin E (alone or in combination) had significant effects on non-HDL-C (p = 0.004), atherogenic Index of Plasma (AIP) (p = <0.001) and lipid accumulation product (LAP) (p <0.001) and SBP (p = 0.005). coenzyme Q10 0-6 selenium binding protein 1 Homo sapiens 202-205 31349945-10 2019 Co-Q10 and vitamin E (alone or in combination) had significant effects on non-HDL-C (p = 0.004), atherogenic Index of Plasma (AIP) (p = <0.001) and lipid accumulation product (LAP) (p <0.001) and SBP (p = 0.005). Vitamin E 11-20 selenium binding protein 1 Homo sapiens 202-205 30520848-9 2019 Clonidine reduced SBP to less than 140 mmHg in 19/61. Clonidine 0-9 selenium binding protein 1 Homo sapiens 18-21 30051193-8 2019 Those who had IV nicardipine had significantly less BPV (p = 0.04) and was more likely to attain an SBP goal < 140 mmHg (p < 0.01). Nicardipine 17-28 selenium binding protein 1 Homo sapiens 100-103 30774500-11 2019 Conclusion: Lercanidipine and lercanidipine/enalapril for stage 1 or 2 hypertension highly improves office SBP and DBP, overall 24-hour BP, daytime BP, and nighttime BP, also reducing BPV with few adverse effects. lercanidipine 12-25 selenium binding protein 1 Homo sapiens 107-110 30774500-11 2019 Conclusion: Lercanidipine and lercanidipine/enalapril for stage 1 or 2 hypertension highly improves office SBP and DBP, overall 24-hour BP, daytime BP, and nighttime BP, also reducing BPV with few adverse effects. lercanidipine 30-43 selenium binding protein 1 Homo sapiens 107-110 30774500-11 2019 Conclusion: Lercanidipine and lercanidipine/enalapril for stage 1 or 2 hypertension highly improves office SBP and DBP, overall 24-hour BP, daytime BP, and nighttime BP, also reducing BPV with few adverse effects. Enalapril 44-53 selenium binding protein 1 Homo sapiens 107-110 30774977-7 2019 The corresponding sensitivity and specificity of the DBT were 40.9 and 90.9% respectively if SBP drop was > 30 mmHg. dbt 53-56 selenium binding protein 1 Homo sapiens 93-96 30774977-8 2019 Conclusion: The DBT, even though could not be clinically applied to all patients, was proven to be a potential screening and diagnostic test for white-coat effect in Chinese hypertensive patients with a pre-test SBP of >=165 mmHg and who were not taking beta-adrenergic blockers. dbt 16-19 selenium binding protein 1 Homo sapiens 212-215 31031490-14 2019 Maximum rise in SBP, DBP, and MAP was 5.49%, 6.03%, and 5.80% for fentanyl group and 12.88%, 9.37%, and 10.86% for nalbuphine group, respectively. Fentanyl 66-74 selenium binding protein 1 Homo sapiens 16-19 29580127-8 2019 Amiloride reduced SBP and DBP to below baseline levels in NT (p < 0.05) and HT (p < 0.001) subjects. Amiloride 0-9 selenium binding protein 1 Homo sapiens 18-21 30042037-10 2019 ICISDelta kinetics could differentiate between SBP and culture-negative SBP patients. icisdelta 0-9 selenium binding protein 1 Homo sapiens 47-50 30042037-10 2019 ICISDelta kinetics could differentiate between SBP and culture-negative SBP patients. icisdelta 0-9 selenium binding protein 1 Homo sapiens 72-75 29985205-7 2019 Meta-analysis also showed that the beta-coefficients of SBP and DBP associated with per 1 mIU/l increase in TSH level were 0.78 (95% CI 0.37-1.18, P < 0.001) and 0.45 (95% CI 0.15-0.76, P = 0.004), respectively. Thyrotropin 108-111 selenium binding protein 1 Homo sapiens 56-59 31727240-5 2019 Thus, exclusively in the presence of biotin, which liberates HMGB1-SBP-GFP from its nuclear hook, immunogenic cell death (ICD) inducers such as anthracyclines are able to cause the nucleo-cytoplasmic translocation of HMGB1-SBP-GFP. Biotin 37-43 selenium binding protein 1 Homo sapiens 67-70 31727240-5 2019 Thus, exclusively in the presence of biotin, which liberates HMGB1-SBP-GFP from its nuclear hook, immunogenic cell death (ICD) inducers such as anthracyclines are able to cause the nucleo-cytoplasmic translocation of HMGB1-SBP-GFP. Biotin 37-43 selenium binding protein 1 Homo sapiens 223-226 31727240-5 2019 Thus, exclusively in the presence of biotin, which liberates HMGB1-SBP-GFP from its nuclear hook, immunogenic cell death (ICD) inducers such as anthracyclines are able to cause the nucleo-cytoplasmic translocation of HMGB1-SBP-GFP. Anthracyclines 144-158 selenium binding protein 1 Homo sapiens 67-70 31727240-5 2019 Thus, exclusively in the presence of biotin, which liberates HMGB1-SBP-GFP from its nuclear hook, immunogenic cell death (ICD) inducers such as anthracyclines are able to cause the nucleo-cytoplasmic translocation of HMGB1-SBP-GFP. Anthracyclines 144-158 selenium binding protein 1 Homo sapiens 223-226 31860850-10 2019 In the 1st group, correlation between UA and BP was moderate for SBP - r = +0,34 and weak for DBP - r = +0,29; in the 2nd group: SBP - r = +0,49 and r = +0,35 for DBP. Uric Acid 38-40 selenium binding protein 1 Homo sapiens 65-68 30943497-4 2019 RESULTS: Ambulatory monitoring showed that during night-time SBP and DBP values were unaffected by bromazepam as compared to placebo, whereas SBP was significantly reduced by propranolol both when taken alone and in combination with bromazepam. Propranolol 175-186 selenium binding protein 1 Homo sapiens 142-145 28988315-7 2018 The analysis of the association between polyphenol intake and biological parameters showed a significant negative association between polyphenol intake and the levels of systolic and diastolic blood pressure (SBP and DBP), GGT, and alanine aminotransferase (ALT) after adjusting for age, smoking habit, energy intake and alcohol intake. Polyphenols 40-50 selenium binding protein 1 Homo sapiens 209-212 30442022-9 2018 Key messages Sodium consumption correlated positively with CV risk factors: age, smoking, SBP, BMI and LDL-cholesterol. Sodium 13-19 selenium binding protein 1 Homo sapiens 90-93 30442022-11 2018 Sodium consumption as a continuous variable was independently associated with AF events when age, BMI, smoking, SBP, LAD, LVMI and the use of any antihypertensive therapy were considered. Sodium 0-6 selenium binding protein 1 Homo sapiens 112-115 30533001-2 2018 Objective To examine whether serum 25-hydroxyvitamin D2+3 (s-25OHD) in cord and pregnancy associates with systolic and diastolic BP (SBP; DBP) in children up to 3 years of age. 25-Hydroxyvitamin D 2 35-55 selenium binding protein 1 Homo sapiens 133-136 28988315-7 2018 The analysis of the association between polyphenol intake and biological parameters showed a significant negative association between polyphenol intake and the levels of systolic and diastolic blood pressure (SBP and DBP), GGT, and alanine aminotransferase (ALT) after adjusting for age, smoking habit, energy intake and alcohol intake. Polyphenols 134-144 selenium binding protein 1 Homo sapiens 209-212 29947099-11 2018 Both dapagliflozin regimens decreased body weight and SBP, with a lower incidence of hypoglycaemia compared with glimepiride. dapagliflozin 5-18 selenium binding protein 1 Homo sapiens 54-57 29995698-7 2018 W-SD was independently associated with older age, history of cardiovascular disease, diagnosis of diabetic, hypertensive and polycystic nephropathy, and higher 24 h SBP whereas no association with eGFR and proteinuria was found. w-sd 0-4 selenium binding protein 1 Homo sapiens 165-168 29524090-7 2018 Multiple regression analysis showed that percentage of sleep time with oxygen saturation < 90% (TST90) and SBP index correlated more with mean level of awakeness and sleep SBP than with apnea-hypopnea index (AHI). Oxygen 71-77 selenium binding protein 1 Homo sapiens 175-178 29524090-8 2018 Analysis of all apnea events demonstrated that SBP and the frequency of BP fluctuations were more remarkable following hypoxia than following arousal; SBP correlated more with oxygen desaturation degree (r = 0.388, p < 0.01) and minimal SpO2 (r = 0.392, p < 0.01) than with apnea length and desaturation duration. Oxygen 178-184 selenium binding protein 1 Homo sapiens 153-156 29577589-7 2018 SBP/LVEDP (AUC = 0.76) and SBP (AUC = 0.77) had a stronger association with in-hospital mortality than did LVEDP (AUC = 0.66) or PP (AUC = 0.64). lvedp 4-9 selenium binding protein 1 Homo sapiens 0-3 30068892-8 2018 Serum TSH within new reference range had a linear correlation with SBP, TC and LDL-C in subjects aged <60 years. Thyrotropin 6-9 selenium binding protein 1 Homo sapiens 67-70 30445973-12 2018 CONCLUSION: Associations between OS and SBP were observed mainly when initial SBP is within the normal range, and are mainly explained by cardiovascular factors, requiring physician"s particular attention to people exposed to these OS. Osmium 33-35 selenium binding protein 1 Homo sapiens 40-43 30445973-12 2018 CONCLUSION: Associations between OS and SBP were observed mainly when initial SBP is within the normal range, and are mainly explained by cardiovascular factors, requiring physician"s particular attention to people exposed to these OS. Osmium 33-35 selenium binding protein 1 Homo sapiens 78-81 30445973-12 2018 CONCLUSION: Associations between OS and SBP were observed mainly when initial SBP is within the normal range, and are mainly explained by cardiovascular factors, requiring physician"s particular attention to people exposed to these OS. Osmium 232-234 selenium binding protein 1 Homo sapiens 40-43 30445973-12 2018 CONCLUSION: Associations between OS and SBP were observed mainly when initial SBP is within the normal range, and are mainly explained by cardiovascular factors, requiring physician"s particular attention to people exposed to these OS. Osmium 232-234 selenium binding protein 1 Homo sapiens 78-81 30400135-1 2018 Selenium-binding protein 1 (SBP1) is a highly conserved protein that covalently binds selenium. Selenium 86-94 selenium binding protein 1 Homo sapiens 0-26 30400135-1 2018 Selenium-binding protein 1 (SBP1) is a highly conserved protein that covalently binds selenium. Selenium 86-94 selenium binding protein 1 Homo sapiens 28-32 30400135-2 2018 SBP1 may play important roles in several fundamental physiological functions, including protein degradation, intra-Golgi transport, cell differentiation, cellular motility, redox modulation, and the metabolism of sulfur-containing molecules. Sulfur 213-219 selenium binding protein 1 Homo sapiens 0-4 30021759-6 2018 Neither high- nor low-phosphate diet nor vitamin D affected endothelial function or arterial elasticity.Conclusions Increased phosphate intake (controlled for sodium) significantly increases SBP, DBP, and PR in humans with normal renal function, in part, by increasing sympathoadrenergic activity. Phosphates 126-135 selenium binding protein 1 Homo sapiens 191-194 30005252-11 2018 CONCLUSION: In this population, there was a significant association between BMF use and increased SBP, CIMT and pre-hypertension. BMF 76-79 selenium binding protein 1 Homo sapiens 98-101 30298835-11 2018 Both SBP and DBP are of critical importance in the primary prevention of AAD-related death in apparently healthy subjects. L-2-Aminoadipic acid 73-76 selenium binding protein 1 Homo sapiens 5-8 30469639-9 2018 The data redundancy requirement as well as the optimal illumination scheme of AADPC are analyzed and discussed based on several simulations, suggesting that the spatial undersampling can be mitigated through the iterative algorithm that uses only 4 images, yielding a nearly 4-fold increase in the space-bandwidth product (SBP) compared to the conventional DPC approach. dpc 80-83 selenium binding protein 1 Homo sapiens 323-326 30051205-12 2018 The SBP at ER discharge was significantly lower in the patients with follow-up BP < 140/90 compared to those with BP > 140/90 mmHg (158.8 +- 16.9 vs. 164.2 +- 16.6 mmHg, P < 0.01). bp > 117-123 selenium binding protein 1 Homo sapiens 4-7 29846329-6 2018 OWCET was associated with an increased risk of both CVD [HR 1.25 (95% CI 1.02-1.52)] and CHD [HR 1.35 (95% CI 1.01-1.80)] events independently of traditional risk factors (age, sex, total cholesterol, HDL, cigarettes and BMI) including SBP. owcet 0-5 selenium binding protein 1 Homo sapiens 236-239 29802952-7 2018 DDS-2 was an independent determinant of SBP (beta = 1.89, 95% CI 0.14, 3.64), DBP (beta = 1.19, 95% CI 0.16, 2.21) and blood pressure target (OR = 2.09, 95% CI 1.12, 3.83). dds-2 0-5 selenium binding protein 1 Homo sapiens 40-43 29927841-8 2018 RESULTS: Total testosterone and SHBG demonstrated significant inverse correlations with SBP whereas DHEAS was not significantly associated with BP. Testosterone 15-27 selenium binding protein 1 Homo sapiens 88-91 30347864-7 2018 A significant positive correlation was identified between TC and LDL-C levels, regardless of BMI and age, whilst SBP correlated only with serum glucose concentration. Glucose 144-151 selenium binding protein 1 Homo sapiens 113-116 29916994-6 2018 A positive significant association between uric acid, and office, daytime and night-time SBP, insulin and triglycerides was observed. Uric Acid 43-52 selenium binding protein 1 Homo sapiens 89-92 29916994-10 2018 Moreover, in a multiple regression analysis, uric acid was significantly related with male sex, waist circumference, both office and night-time SBP and birth weight. Uric Acid 45-54 selenium binding protein 1 Homo sapiens 144-147 30393219-11 2018 BMI, SBP pressure were significantly higher (P<0.001) in MI patients with DMT-II when compared with MI patients without DMT-II. dmt-ii 77-83 selenium binding protein 1 Homo sapiens 5-8 28645696-5 2018 RESULTS: MEX and ACEiMEX groups improved all physical functional status outcomes, decreased systolic (SBP) and diastolic blood pressure (p<0.001) and augmented the physical functioning, role physical and physical component score (PCS) (p<0.05), but also bodily pain (p<0.05). aceimex 17-24 selenium binding protein 1 Homo sapiens 102-105 28988282-12 2018 This might be proved by the results of the margin of the exposure (MOE) value evaluation in the samples containing the maximum Pb concentrations, showing a high risk of CKD and SBP in high and extreme consumption groups. Lead 127-129 selenium binding protein 1 Homo sapiens 177-180 29570512-10 2018 The difference in 24-h SBP between the two treatments was 3.99 mmHg (95% confidence interval 1.35-6.63; P = 0.004), higher in the effervescent paracetamol treatment period. Acetaminophen 143-154 selenium binding protein 1 Homo sapiens 23-26 29570512-11 2018 Similarly, the per-protocol analysis showed a difference in 24-h SBP between the two groups of 5.04 mmHg (95% confidence interval 1.80-8.28; P = 0.004), higher in the effervescent paracetamol treatment period. Acetaminophen 180-191 selenium binding protein 1 Homo sapiens 65-68 29570512-14 2018 CONCLUSION: Effervescent paracetamol tablets are responsible for a significant daytime and overall increase in ambulatory 24-h SBP. Acetaminophen 25-36 selenium binding protein 1 Homo sapiens 127-130 30122242-9 2018 One unit dip in SBP and DBP will reduce the chances of survival by 0.697 times and 0.586 times respectively. 3,5-diisopropylsalicylic acid 9-12 selenium binding protein 1 Homo sapiens 16-19 29575641-6 2018 Patients who died were more likely to have underlying congenital heart disease; have a higher increase in the concentration of carbon dioxide in the blood (pCO2 ) with a corresponding greater mean percentage decrease in pH and percentage rise in NT-pro BNP during PH exacerbations; more likely to have been on medications for pulmonary hypertension; and have a higher RVSP/SBP (%) ratio and S/D ratio. Carbon Dioxide 127-141 selenium binding protein 1 Homo sapiens 373-376 29575641-6 2018 Patients who died were more likely to have underlying congenital heart disease; have a higher increase in the concentration of carbon dioxide in the blood (pCO2 ) with a corresponding greater mean percentage decrease in pH and percentage rise in NT-pro BNP during PH exacerbations; more likely to have been on medications for pulmonary hypertension; and have a higher RVSP/SBP (%) ratio and S/D ratio. pco2 156-160 selenium binding protein 1 Homo sapiens 373-376 30122242-10 2018 CONCLUSION: In advanced HFrEF patients with Lower SBP & DBP and dippers have lesser survival compared to those with higher SBP & DBP and non-dippers. Adenosine Monophosphate 55-58 selenium binding protein 1 Homo sapiens 50-53 29751936-14 2018 We found a significant correlation of cholecalciferol with the variability of SBP during the day. Cholecalciferol 38-53 selenium binding protein 1 Homo sapiens 78-81 30203770-5 2018 This study demonstrated that atorvastatin was used to treat patients with diastolic dysfunction and exercise hypertension by lowering blood pressure and reducing exercise SBP, anti-inflammatory and improving vascular endothelial function. Atorvastatin 29-41 selenium binding protein 1 Homo sapiens 171-174 30119558-1 2018 An efficient method to implement the coarse integral holographic (CIH) concept for dynamic CIH displays is to scan the information generated from a spatial light modulator (SLM) of a low space bandwidth product (SBP) but high bandwidth to form the hologram array for the integral optics. cih 66-69 selenium binding protein 1 Homo sapiens 212-215 29522901-4 2018 It was observed that AC genotype individuals had increased basal-DBP and post-caffeine SBP when compared to AA individuals. Caffeine 78-86 selenium binding protein 1 Homo sapiens 87-90 29522901-5 2018 Additionally, acute caffeine ingestion increased SBP only in the AC group. Caffeine 20-28 selenium binding protein 1 Homo sapiens 49-52 29807620-15 2018 In the subgroup of olmesartan-treated controlled hypertensive patients, the switch to another ARB lead to uncontrolled hypertension for 20% of patients with a 12.1mmHg increase in SBP. olmesartan 19-29 selenium binding protein 1 Homo sapiens 180-183 29659631-8 2018 Post preoperative infusion, paracetamol decreased SBP by a mean (SD) of 13 (18) mmHg, p = 0.02, compared to a mean (SD) of 1 (11) mmHg with saline. Acetaminophen 28-39 selenium binding protein 1 Homo sapiens 50-53 29389742-9 2018 Future clinical trials are warranted to test BP-lowering effects in acute ischemic stroke patients by baseline SBP levels. Benzo(a)pyrene 45-47 selenium binding protein 1 Homo sapiens 111-114 29274100-5 2018 RESULTS: For 20 mg cediranib once-daily oral administration, the mean increase in DBP and SBP was predicted to be 7 (95% CI 3-13) and 8 mmHg (95% CI 3-16), respectively, while the probability of mild diarrhoea, but not the severity, was predicted to increase over time. cediranib 19-28 selenium binding protein 1 Homo sapiens 90-93 29721235-11 2018 After the intervention period, SBP (P < 0.001), DBP (P < 0.001) and FBS (P < 0.001) reduced in ALA group compared with placebo group, significantly. Thioctic Acid 104-107 selenium binding protein 1 Homo sapiens 31-34 29721235-13 2018 Conclusions: Results of this trial indicated that 12 weeks supplementation with 600 mg ALA has beneficial effects on SBP, DBP, and FBS but has no effect on insulin level. Thioctic Acid 87-90 selenium binding protein 1 Homo sapiens 117-120 29334491-6 2018 At 8 weeks, both AZL-M/CTD FDCs reduced 24-h SBP more than OLM/HCTZ (-26.4 and -27.9 versus -20.7 mmHg; both P < 0.001), and higher proportions in both AZL-M/CTD groups achieved target BP compared with the OLM/HCTZ group (69.4 and 68.9 versus 54.7%, both P < 0.001). azl-m/ctd fdcs 17-31 selenium binding protein 1 Homo sapiens 45-48 29805801-8 2018 The most significant decrease of sBP was associated with treatment by nitre, hydro, telmi, and urapidil (>19 mmHg). urapidil 95-103 selenium binding protein 1 Homo sapiens 33-36 29805801-10 2018 The most significant decrease of both sBP and dBP was associated with treatment using 3-drug combination of telmi + hydro + spironolactone (41 and 16 mmHg, resp.), telmi + hydro + nitre (34 and 15 mmHg, resp.), and telmi + hydro + urapidil (34 and 15 mmHg, resp.). telmi + hydro + spironolactone 108-138 selenium binding protein 1 Homo sapiens 38-41 29805801-10 2018 The most significant decrease of both sBP and dBP was associated with treatment using 3-drug combination of telmi + hydro + spironolactone (41 and 16 mmHg, resp.), telmi + hydro + nitre (34 and 15 mmHg, resp.), and telmi + hydro + urapidil (34 and 15 mmHg, resp.). urapidil 229-239 selenium binding protein 1 Homo sapiens 38-41 29498204-4 2018 In hypertensives, increased PBR was associated with increased cSBP, PWV, and decreased CFR and GLS after adjustment for age, sex, BMI, smoking LV mass, heart rate, hyperlipidemia, and office SBP (P < .05). pentabromophenol 28-31 selenium binding protein 1 Homo sapiens 63-66 28857451-9 2018 Ertugliflozin significantly reduced FPG, body weight, SBP and DBP vs placebo. ertugliflozin 0-13 selenium binding protein 1 Homo sapiens 54-57 29065098-7 2018 RESULTS: Placebo-adjusted brachial SBP decreased 18 mmHg (P < 0.001) during NaNO2 infusion in EHT and 12 mmHg (P < 0.001) in CON (Pbetween = 0.024). pbetween 136-144 selenium binding protein 1 Homo sapiens 35-38 29094330-10 2018 In a multivariate model adjusted for age, BMI, diabetes, hypertension, alcohol drinking, SBP, total cholesterol, and eGFR, the odds ratio for rapid decline of renal function increased across quartiles of serum uric acid level, reaching a 1.32 (95% CI 1.02-2.97) for the top quartile compared to the lowest quartile (P for trend < 0.001). Uric Acid 210-219 selenium binding protein 1 Homo sapiens 89-92 29325769-6 2018 Our findings provide the molecular basis for the differences in affinity between SB269652 derivatives, and reveal how changes to interactions made by the primary pharmacophore of SB269652 in the orthosteric pocket can confer changes in the interactions made by the secondary pharmacophore in the SBP. SB269652 179-187 selenium binding protein 1 Homo sapiens 296-299 31038034-7 2018 Meta-analysis on 26 studies with 1789 type 2 diabetic subjects showed that vitamin D significantly reduced systolic blood pressure (SBP; -0.97 mmHg, 95 % CI: -1.94, -0.001, P = 0.050), but not diastolic blood pressure (DBP; -0.10 mmHg, 95 % CI: -0.22, 0.02, P = 0.087). Vitamin D 75-84 selenium binding protein 1 Homo sapiens 132-135 29325769-5 2018 Our results indicate that interaction with the SBP is a requirement for allosteric pharmacology, but that both competitive and allosteric derivatives of SB269652 can display sensitivity to the mutation of a glutamate residue (E952.65) within the SBP. SB269652 153-161 selenium binding protein 1 Homo sapiens 47-50 29325769-5 2018 Our results indicate that interaction with the SBP is a requirement for allosteric pharmacology, but that both competitive and allosteric derivatives of SB269652 can display sensitivity to the mutation of a glutamate residue (E952.65) within the SBP. SB269652 153-161 selenium binding protein 1 Homo sapiens 246-249 29325769-5 2018 Our results indicate that interaction with the SBP is a requirement for allosteric pharmacology, but that both competitive and allosteric derivatives of SB269652 can display sensitivity to the mutation of a glutamate residue (E952.65) within the SBP. Glutamic Acid 207-216 selenium binding protein 1 Homo sapiens 246-249 31038034-8 2018 Subgroup analyses showed that administration of vitamin D in patients with baseline serum 25-hydroxy vitamin D < 50 nmol/l and baseline SBP < 140 mmHg significantly reduced SBP. Vitamin D 48-57 selenium binding protein 1 Homo sapiens 139-142 31038034-8 2018 Subgroup analyses showed that administration of vitamin D in patients with baseline serum 25-hydroxy vitamin D < 50 nmol/l and baseline SBP < 140 mmHg significantly reduced SBP. Vitamin D 48-57 selenium binding protein 1 Homo sapiens 179-182 31038034-9 2018 Moreover, the patients who received vitamin D without Ca co-supplementation showed significant reduction in SBP. Vitamin D 36-45 selenium binding protein 1 Homo sapiens 108-111 31038034-11 2018 This study demonstrated that vitamin D improved SBP in type 2 diabetic patients. Vitamin D 29-38 selenium binding protein 1 Homo sapiens 48-51 29352161-3 2018 SB269652 acts as a negative allosteric modulator (NAM) of the D2R that adopts an extended bitopic pose, in which the tetrahydroisoquinoline moiety interacts with the OBS and the indole-2-carboxamide moiety occupies a secondary binding pocket (SBP). SB269652 0-8 selenium binding protein 1 Homo sapiens 243-246 29337986-2 2018 SB269652, a bitopic ligand that simultaneously binds both the orthosteric binding site (OBS) and a secondary binding pocket (SBP) in both D2R and D3R, was found to be a negative allosteric modulator. SB269652 0-8 selenium binding protein 1 Homo sapiens 125-128 29337986-3 2018 Previous studies identified Glu2.65 in the SBP to be a key determinant of both the affinity of SB269652 and the magnitude of its cooperativity with orthosteric ligands, as the E2.65A mutation decreased both of these parameters. SB269652 95-103 selenium binding protein 1 Homo sapiens 43-46 28985278-7 2018 RESULTS: SBP was lower by 5.1 +- 1.0 mm Hg after WATER than CONTROL over 21 hours (P < 0.001), over awake hours by 5.7 +- 1.1 mm Hg (P < 0.001), and sleep hours by 4.5 +- 0.4 mm Hg (P = 0.004). Water 49-54 selenium binding protein 1 Homo sapiens 9-12 29352161-3 2018 SB269652 acts as a negative allosteric modulator (NAM) of the D2R that adopts an extended bitopic pose, in which the tetrahydroisoquinoline moiety interacts with the OBS and the indole-2-carboxamide moiety occupies a secondary binding pocket (SBP). 1,2,3,4-tetrahydroisoquinoline 117-139 selenium binding protein 1 Homo sapiens 243-246 29485915-5 2018 RESULTS: The level of baPWV showed a significantly positive correlation with BMI, SBP, DBP, TG, TC, cystatin C (r = 0.251, p < 0.001), and a negative correlation with HDL-C. And when adjustment for age, BMI, and cigarette smoking, these correlations remain significantly. bapwv 22-27 selenium binding protein 1 Homo sapiens 82-85 29535818-5 2018 Furthermore, SELENBP1 re-expression alters the sensitivity of melanoma cells for Vemurafenib treatment. Vemurafenib 81-92 selenium binding protein 1 Homo sapiens 13-21 29535789-8 2018 Conclusion: Current study results, along with previously reported findings on this cohort, provide evidence for the hypothesis that exposure to Pb leads to small increases in sBP and perhaps to increased circulating levels of sVCAM-1 and sICAM-1 later in life. Lead 144-146 selenium binding protein 1 Homo sapiens 175-178 29421796-9 2018 Controlling volume variation, avoiding hypoalbuminemia and reducing blood calcium levels might reduce SBP variability and thereby improve prognoses in these patients. Calcium 74-81 selenium binding protein 1 Homo sapiens 102-105 29363988-7 2018 RESULTS: After 12 weeks of brisk walking, SBP of TRG during resting, low and high-intensity exercise was significantly reduced by 8.3mmHg, 15.6mmHg, and 22.6mmHg, respectively; while HR of TRG"s during resting, low and high intensity was significantly reduced by 3.6beats/minute, 8.7beats/minute and 11.3beats/minute, respectively. trg 49-52 selenium binding protein 1 Homo sapiens 42-45 29400573-6 2018 Against the no-educated clinic, the educated clinic had significant higher percent decline of zero EDP on SBP (31.5% vs -2.6%) and DBP (36.9% vs -14.3%) in 2013, and in 2014 (SBP 38.0% vs 11.6%; DBP 42.8% vs -4.0%). 2-ethyl-3,5-dimethylpyrazine 99-102 selenium binding protein 1 Homo sapiens 106-109 30259507-6 2018 RESULTS: Both perindopril and telmisartan reduced systolic (SBP) and diastolic blood pressure (DBP). Perindopril 14-25 selenium binding protein 1 Homo sapiens 60-63 30259507-6 2018 RESULTS: Both perindopril and telmisartan reduced systolic (SBP) and diastolic blood pressure (DBP). Telmisartan 30-41 selenium binding protein 1 Homo sapiens 60-63 29390287-9 2017 Higher sUA was significantly associated with higher SBP and DBP in the 41- to 50-year-old participants (SBP, beta = 0.35, P < .001; DBP, beta = .29, P < .001; after adjustment for age, sex, total cholesterol, estimated glomerular filtration rate, and fasting plasma glucose). sua 7-10 selenium binding protein 1 Homo sapiens 52-55 29311704-6 2017 For SBP, mean decrease was higher with ramipril (-16.7 +- 8.4 mm Hg) than with kinkeliba (-12.2 +- 6.6 mm Hg, P = 0.016) and bissap (-11.2 +- 3.3 mm Hg, P = 0.001). Ramipril 39-47 selenium binding protein 1 Homo sapiens 4-7 30081801-6 2018 RESULTS: Both groups showed a positive effect of both moxonidine and bisoprolol on hypertension during treatment both as monotherapy and in the group of patients receiving combined antihypertensive therapy: a decrease in SBP and DBP in the 1st group was 13.6% and 12.8% respectively, and in the 2nd group - 13.7% and 15% respectively, while achieving normal values. moxonidine 54-64 selenium binding protein 1 Homo sapiens 221-224 30081801-6 2018 RESULTS: Both groups showed a positive effect of both moxonidine and bisoprolol on hypertension during treatment both as monotherapy and in the group of patients receiving combined antihypertensive therapy: a decrease in SBP and DBP in the 1st group was 13.6% and 12.8% respectively, and in the 2nd group - 13.7% and 15% respectively, while achieving normal values. Bisoprolol 69-79 selenium binding protein 1 Homo sapiens 221-224 29255262-2 2018 We show that SELENBP1 is a methanethiol oxidase (MTO), related to the MTO in methylotrophic bacteria, that converts methanethiol to H2O2, formaldehyde, and H2S, an activity not previously known to exist in humans. methylmercaptan 27-39 selenium binding protein 1 Homo sapiens 13-21 29255262-2 2018 We show that SELENBP1 is a methanethiol oxidase (MTO), related to the MTO in methylotrophic bacteria, that converts methanethiol to H2O2, formaldehyde, and H2S, an activity not previously known to exist in humans. Hydrogen Peroxide 132-136 selenium binding protein 1 Homo sapiens 13-21 29255262-2 2018 We show that SELENBP1 is a methanethiol oxidase (MTO), related to the MTO in methylotrophic bacteria, that converts methanethiol to H2O2, formaldehyde, and H2S, an activity not previously known to exist in humans. Formaldehyde 138-150 selenium binding protein 1 Homo sapiens 13-21 29255262-2 2018 We show that SELENBP1 is a methanethiol oxidase (MTO), related to the MTO in methylotrophic bacteria, that converts methanethiol to H2O2, formaldehyde, and H2S, an activity not previously known to exist in humans. Hydrogen Sulfide 156-159 selenium binding protein 1 Homo sapiens 13-21 29288159-7 2017 We found that rs6078905 C-allele carriers had a better BP response to HCTZ versus noncarriers ( SBP/ DBP: -11.4/-6.9 versus -6.8/-3.5 mm Hg; SBP P=6.7E-04; DBP P=4.8E-04). Hydrochlorothiazide 70-74 selenium binding protein 1 Homo sapiens 96-99 29288159-7 2017 We found that rs6078905 C-allele carriers had a better BP response to HCTZ versus noncarriers ( SBP/ DBP: -11.4/-6.9 versus -6.8/-3.5 mm Hg; SBP P=6.7E-04; DBP P=4.8E-04). Hydrochlorothiazide 70-74 selenium binding protein 1 Homo sapiens 142-145 29288159-9 2017 Last, we observed that rs6078905 significantly affects the baseline level of 4 sphingomyelins (N24:2, N24:3, N16:1, and N22:1; false discovery rate <0.05), from which N24:2 sphingomyelin has a significant correlation with both HCTZ DBP-response (r=-0.42; P=7E-03) and SBP-response (r=-0.36; P=2E-02). Sphingomyelins 79-93 selenium binding protein 1 Homo sapiens 271-274 29190257-11 2017 When controlling for year of admission, mechanism of injury and shock upon arrival (SBP <=90 mm Hg or HR >=120 bpm or base deficit <= 4) indicated T-TC had a 4.5-fold increased odds of death compared to T-PH (OR 4.5, 95% CI 1.23-16.4, p = 0.02). t-tc 156-160 selenium binding protein 1 Homo sapiens 84-87 29390287-7 2017 The association between sUA concentration and SBP and DBP was examined using Pearson"s correlation test, multivariate linear regression, and logistic regression analysis.The prevalence of hypertension and HUA increased with age (P < .001). sua 24-27 selenium binding protein 1 Homo sapiens 46-49 29390287-9 2017 Higher sUA was significantly associated with higher SBP and DBP in the 41- to 50-year-old participants (SBP, beta = 0.35, P < .001; DBP, beta = .29, P < .001; after adjustment for age, sex, total cholesterol, estimated glomerular filtration rate, and fasting plasma glucose). sua 7-10 selenium binding protein 1 Homo sapiens 104-107 29183297-8 2017 RESULTS: The risk increased by 4% and 39% per each 10 mmHg and 1 mmol/L increase in SBP/DBP and TC, respectively; additionally, females had a 70% lower risk. Diosmin 88-91 selenium binding protein 1 Homo sapiens 84-87 28285988-11 2017 Multivariate stepwise regression analysis showed that the satisfaction DTSQ scores for HbA1c (p<0.001), h of sleep (p<0.001), neuropathy (p=0.007), diabetic education (p=0.014), SBP (mmHg) (p=0.021) DBP (mmHg) (p=0.028) were identified as significantly associated with higher treatment satisfaction. DTSQ 71-75 selenium binding protein 1 Homo sapiens 184-187 28946991-7 2017 To address these problems, an ensemble with an asymptotic approach (based on combining the bootstrap with the DBN-DNN technique) is utilized to generate the pseudo features needed to estimate the SBP and DBP. dbn-dnn 110-117 selenium binding protein 1 Homo sapiens 196-199 28387058-1 2017 In the EMPA-REG BP trial, empagliflozin significantly reduced systolic and diastolic blood pressure (SBP and DBP) compared with placebo at week 12 in patients with type 2 diabetes mellitus (T2DM) and hypertension. empagliflozin 26-39 selenium binding protein 1 Homo sapiens 101-104 28946991-11 2017 RESULTS: The proposed method can mitigate the estimation uncertainty such as large the standard deviation of error (SDE) on comparing the proposed DBN-DNN ensemble regression estimator with the DBN-DNN single regression estimator, we identify that the SDEs of the SBP and DBP are reduced by 0.58 and 0.57 mmHg, respectively. dbn-dnn 147-154 selenium binding protein 1 Homo sapiens 264-267 28946991-11 2017 RESULTS: The proposed method can mitigate the estimation uncertainty such as large the standard deviation of error (SDE) on comparing the proposed DBN-DNN ensemble regression estimator with the DBN-DNN single regression estimator, we identify that the SDEs of the SBP and DBP are reduced by 0.58 and 0.57 mmHg, respectively. dbn-dnn 194-201 selenium binding protein 1 Homo sapiens 264-267 28946991-11 2017 RESULTS: The proposed method can mitigate the estimation uncertainty such as large the standard deviation of error (SDE) on comparing the proposed DBN-DNN ensemble regression estimator with the DBN-DNN single regression estimator, we identify that the SDEs of the SBP and DBP are reduced by 0.58 and 0.57 mmHg, respectively. SDES 252-256 selenium binding protein 1 Homo sapiens 264-267 28922068-9 2017 These data further support the safety and tolerability of long-term flaxseed lignan-enriched complex supplementation in older adults and identify an ability to favorably modulate SBP, an important risk factor in cardiovascular disease. Lignans 77-83 selenium binding protein 1 Homo sapiens 179-182 28887302-0 2017 Mechanisms of zinc binding to the solute-binding protein AztC and transfer from the metallochaperone AztD. aztc 57-61 selenium binding protein 1 Homo sapiens 34-56 28887302-6 2017 Here, we present intact structures for the zinc-specific SBP AztC from the bacterium Paracoccus denitrificans in the zinc-bound and apo-states. aztc 61-65 selenium binding protein 1 Homo sapiens 57-60 29051578-7 2017 High-salt diet for males manifested a slightly increasing positive association with higher SBP only for high quantiles (>=70), but with a higher DBP for middle part of the quantiles (30~75), compared with bland diet. Salts 5-9 selenium binding protein 1 Homo sapiens 91-94 28505062-5 2017 RESULTS: Multivariable adjusted analyses showed an inverse relationship between SBP with depression (coefficient = -0.10; P = 0.012) and anxiety (after excluding two outliers with SBP > 156 mmHg, coefficient = -0.13; P = 0.018) scores, independent of sex, BMI, female hormonal contraceptive use, alcohol consumption, birth weight and maternal hypertension in pregnancy. Alcohols 299-306 selenium binding protein 1 Homo sapiens 80-83 28509725-5 2017 At 15, 30, and 60 days of follow-up, average SBP/DBP reduction in telmisartan and HCTZ group was 12.5/8.0, 14.3/9.1, 12.8/7.2, 11.0/5.8, 13.6/7.1, and 11.5/5.3 mmHg, respectively. Telmisartan 66-77 selenium binding protein 1 Homo sapiens 45-48 28509725-7 2017 SBP reduction was positively related to increasing urinary sodium and PP levels for patients in both groups but increased faster with increasing PP in HCTZ than in telmisartan (P = 0.0238 for group x PP). Sodium 59-65 selenium binding protein 1 Homo sapiens 0-3 28509725-7 2017 SBP reduction was positively related to increasing urinary sodium and PP levels for patients in both groups but increased faster with increasing PP in HCTZ than in telmisartan (P = 0.0238 for group x PP). Hydrochlorothiazide 151-155 selenium binding protein 1 Homo sapiens 0-3 28509725-7 2017 SBP reduction was positively related to increasing urinary sodium and PP levels for patients in both groups but increased faster with increasing PP in HCTZ than in telmisartan (P = 0.0238 for group x PP). Telmisartan 164-175 selenium binding protein 1 Homo sapiens 0-3 28582281-8 2017 Unadjusted analysis showed higher cotinine levels were associated with lower SBP, total cholesterol, LDL cholesterol, and triglyceride. Cotinine 34-42 selenium binding protein 1 Homo sapiens 77-80 28387058-7 2017 In conclusion, empagliflozin significantly reduced mean 24-hour SBP compared with placebo in dippers and non-dippers. empagliflozin 15-28 selenium binding protein 1 Homo sapiens 64-67 28387058-2 2017 In a post-hoc analysis, we assessed the effect of empagliflozin on SBP and DBP using 24-hour ambulatory BP monitoring in patients categorized as dippers (sleep-time mean SBP <= 90% of awake-time mean; n = 417) or non-dippers (sleep-time mean SBP > 90% of awake-time mean; n = 350). empagliflozin 50-63 selenium binding protein 1 Homo sapiens 67-70 28434969-6 2017 Propranolol blocked the decrease in SBP and attenuated HR increase at 100mg/kg mirabegron. Propranolol 0-11 selenium binding protein 1 Homo sapiens 36-39 28306636-7 2017 After 1 month, superior SBP (-3.1 mmHg, P = 0.02) and DBP (-2.8 mmHg, P < 0.001) reductions were observed with perindopril/indapamide/amlodipine, which were even more pronounced after excluding white-coat effect in the sustained hypertension population (-5.3/-3.7 mmHg). Perindopril 114-125 selenium binding protein 1 Homo sapiens 24-27 28932292-6 2017 Furthermore, the MTX group had significantly lower 24-hour peripheral and central SBP and DBP and PWV versus the non-MTX group (p < 0.01 for all comparisons). Methotrexate 17-20 selenium binding protein 1 Homo sapiens 82-85 28276722-7 2017 A correlation between the dose of naproxen and an increase in SBP of 7 mm Hg was found. Naproxen 34-42 selenium binding protein 1 Homo sapiens 62-65 28276722-10 2017 In intermediate and frequent users of NSAID there was a dose response relation with naproxen and SBP which was not found in diclofenac and ibuprofen. Naproxen 84-92 selenium binding protein 1 Homo sapiens 97-100 28634217-13 2017 CONCLUSIONS: Although higher BP levels are associated with increased CVD risk, in the modern era, the majority of incident CVD events occur in US adults with SBP/DBP <140/90 mm Hg. Benzo(a)pyrene 29-31 selenium binding protein 1 Homo sapiens 158-161 28275946-10 2017 Compared to MRA, CAA had the highest probability of being more effective, further reducing 24-h SBP (-4.8 mmHg [-13.0, 3.7]) and 24-h DBP (-9.7 mmHg [-18, -0.63]). caa 17-20 selenium binding protein 1 Homo sapiens 96-99 31758763-8 2017 RESULTS: After 12 weeks on the system, patients with a baseline SBP of 140 mm Hg or higher reduced SBP by 10.8 mm Hg (95% CI -14.5 to -7.2, P<.001) and DBP by 6.6 mm Hg (95% CI -9.9 to -3.4, P=.002), but no significant changes were observed in overall BPs and BPs in the group with baseline SBP less than 140 mm Hg. benzo(a)pyrene-3-O-glucuronide 255-258 selenium binding protein 1 Homo sapiens 64-67 31758763-8 2017 RESULTS: After 12 weeks on the system, patients with a baseline SBP of 140 mm Hg or higher reduced SBP by 10.8 mm Hg (95% CI -14.5 to -7.2, P<.001) and DBP by 6.6 mm Hg (95% CI -9.9 to -3.4, P=.002), but no significant changes were observed in overall BPs and BPs in the group with baseline SBP less than 140 mm Hg. benzo(a)pyrene-3-O-glucuronide 263-266 selenium binding protein 1 Homo sapiens 64-67 28740096-2 2017 There have been few data on the relationship between Hcy and central SBP (cSBP). Homocysteine 53-56 selenium binding protein 1 Homo sapiens 69-72 28698169-12 2017 At week 4, DMO resulted in a statistically greater SBP reduction than usual care (mean -21.8, SE 1.5 mm Hg vs mean -12.7, SE 2.8 mmHg; mean difference -9.1, 95% CI -14.0 to -3.3 mm Hg) and maintained a greater reduction at week 12. demethyloleuropein 11-14 selenium binding protein 1 Homo sapiens 51-54 28306636-7 2017 After 1 month, superior SBP (-3.1 mmHg, P = 0.02) and DBP (-2.8 mmHg, P < 0.001) reductions were observed with perindopril/indapamide/amlodipine, which were even more pronounced after excluding white-coat effect in the sustained hypertension population (-5.3/-3.7 mmHg). Indapamide 126-136 selenium binding protein 1 Homo sapiens 24-27 28319596-3 2017 The objective was to conduct a meta-analysis of randomized controlled trials that examined whether dietary nitrate supplementation for more than 1 week has beneficial effects on SBP and DBP. Nitrates 107-114 selenium binding protein 1 Homo sapiens 178-181 28319596-11 2017 Overall, dietary nitrate was associated with a significant decline in SBP [-4.1 mmHg (95% confidence interval: -6.1, -2.2); P < 0.001] and DBP [-2.0 mmHg (95% confidence interval: -3.0, -0.9); P < 0.001]. Nitrates 17-24 selenium binding protein 1 Homo sapiens 70-73 28370525-1 2017 One of the most remarkable bistable materials reported so far is made of pi dimers of a butyl-substituted spirobiphenalenyl boron radical (butyl-SBP). butyl-substituted spirobiphenalenyl boron radical 88-137 selenium binding protein 1 Homo sapiens 145-148 28746172-7 2017 After Bonferroni correction the polymorphism rs4680 (ValMet) in COMT was significantly associated with lower SBP in participants treated with CCBs (P = .009) with an especially strong impact in elderly individuals (age >= 70) alone (Delta = -14.08 mm Hg, P = .0005).These results underline the important role of estrogens and catecholamines in hypertension and the importance of genotype dependent, age-related adjustments of calcium-channel blocker treatment. Val-Met 53-59 selenium binding protein 1 Homo sapiens 109-112 28370525-3 2017 The phase transition of butyl-SBP consists of a spin transition of the constituent pi dimers coupled with an order-disorder transition involving the butyl chains linked to the nitrogen atoms of the superimposed phenalenyl rings of the pi dimer. Nitrogen 176-184 selenium binding protein 1 Homo sapiens 30-33 28843242-13 2017 Among metabolic syndrome indicators, there was a significant direct relationship between vitamin D level with FBS (P=0.013) and SBP (P=0.023). Vitamin D 89-98 selenium binding protein 1 Homo sapiens 128-131 28627203-5 2017 Linear regression analysis was performed to assess the independent association between the mentioned MIBs and SBP/DBP, controlling for several confounders in multiples models. 2-methylisoborneol 101-105 selenium binding protein 1 Homo sapiens 110-113 27499431-5 2017 RESULTS: Compared with 2008, SBP significantly increased in subjects with worsened (and untreated) SUA level, while improved in subjects treated with allopurinol (p < 0.05). sua 99-102 selenium binding protein 1 Homo sapiens 29-32 27499431-5 2017 RESULTS: Compared with 2008, SBP significantly increased in subjects with worsened (and untreated) SUA level, while improved in subjects treated with allopurinol (p < 0.05). Allopurinol 150-161 selenium binding protein 1 Homo sapiens 29-32 27499431-6 2017 In 2012, subjects with worsened (and untreated) SUA level had a significantly higher SBP compared with subjects with unchanged SUA and those with SUA improved after allopurinol treatment (p < 0.05). sua 48-51 selenium binding protein 1 Homo sapiens 85-88 27499431-8 2017 CONCLUSION: It seems that SUA improvement could positively influence the age-related worsening of SBP and FPG in general population. sua 26-29 selenium binding protein 1 Homo sapiens 98-101 27499431-10 2017 SUA improvement could positively influence the age-related worsening of SBP and FPG in general population. sua 0-3 selenium binding protein 1 Homo sapiens 72-75 28593125-9 2017 SBP and DBP significantly increased with age and alcohol use. Alcohols 49-56 selenium binding protein 1 Homo sapiens 0-3 28060189-9 2017 Positive correlation was found during follow-up between baPWV and childhood SBP, as well as SBP, DBP, BMI, heart rate, total cholesterol, low-density lipoprotein cholesterol, triacylglycerol, fasting glucose, and uric acid in adulthood (all P < 0.05). bapwv 56-61 selenium binding protein 1 Homo sapiens 76-79 28430416-2 2017 We expand the photoactivatable chemistry toolbox here with a second reagent, sulfo-SBP (benzophenone). benzophenone 88-100 selenium binding protein 1 Homo sapiens 83-86 28118281-8 2017 Crossover analysis showed nonsignificantly better efficacy of spironolactone addition in 24-h SBP and office SBP reduction than RDN (3.7 mmHg, P = 0.27 and 4.6 mmHg, P = 0.28 in favour of spironolactone addition, respectively). Spironolactone 62-76 selenium binding protein 1 Homo sapiens 94-97 28118281-8 2017 Crossover analysis showed nonsignificantly better efficacy of spironolactone addition in 24-h SBP and office SBP reduction than RDN (3.7 mmHg, P = 0.27 and 4.6 mmHg, P = 0.28 in favour of spironolactone addition, respectively). Spironolactone 62-76 selenium binding protein 1 Homo sapiens 109-112 28060189-10 2017 Results from stepwise multivariate regression analysis showed that men, family history of hypertension, SBP at both baseline and follow-up, fasting glucose, and uric acid in adulthood are independent impact factors of baPWV in adults. bapwv 218-223 selenium binding protein 1 Homo sapiens 104-107 28355168-8 2017 RESULTS: In multivariable analysis, uric acid (per SD of 38 mumol/l) was associated with DBP z-scores [sbeta 0.07; confidence interval (CI), 0.01-1.14], but not with SBP z-scores. Uric Acid 36-45 selenium binding protein 1 Homo sapiens 166-169 28030431-3 2017 The primary assessment was the superiority of LCZ696/amlodipine versus amlodipine in lowering 24-h ambulatory SBP from baseline to week 8. sacubitril and valsartan sodium hydrate drug combination 46-52 selenium binding protein 1 Homo sapiens 110-113 28391629-20 2017 AUTHORS" CONCLUSIONS: Sodium reduction from an average high usual sodium intake level (201 mmol/day) to an average level of 66 mmol/day, which is below the recommended upper level of 100 mmol/day (5.8 g salt), resulted in a decrease in SBP/DBP of 1/0 mmHg in white participants with normotension and a decrease in SBP/DBP of 5.5/2.9 mmHg in white participants with hypertension. Sodium 22-28 selenium binding protein 1 Homo sapiens 314-317 27882931-5 2017 In multivariable linear regression analysis, Sfrp5, Wnt5a, adiponectin, chemerin and hsCRP were associated with both standard deviation score-systolic blood pressure (SDS-SBP) and -diastolic blood pressure (SDS-DBP). Sodium Dodecyl Sulfate 167-170 selenium binding protein 1 Homo sapiens 171-174 28430776-7 2017 Analysis by the adsorption isotherm clearly revealed DAB formed very stable [DAB SBP]adduct adduct at 1:1 molar ration (Phase A). p-Dimethylaminoazobenzene 53-56 selenium binding protein 1 Homo sapiens 81-84 28430776-7 2017 Analysis by the adsorption isotherm clearly revealed DAB formed very stable [DAB SBP]adduct adduct at 1:1 molar ration (Phase A). p-Dimethylaminoazobenzene 77-80 selenium binding protein 1 Homo sapiens 81-84 28430776-8 2017 The equilibrium constant of this colloidal adduct [DAB SBP]adduct was KeqA = , behaving as the most stable and toxic species. p-Dimethylaminoazobenzene 51-54 selenium binding protein 1 Homo sapiens 55-58 28430776-11 2017 Conclusively, this is the first report indicating that [DAB SBP]adduct potentially is capable to damage the Gastro-Duodenal-Hepatic axis. p-Dimethylaminoazobenzene 56-59 selenium binding protein 1 Homo sapiens 60-63 28419159-12 2017 Compared to placebo, potassium supplementation resulted in modest but significant reductions in both SBP (MD -4.25 mmHg; 95% CI: -5.96 to -2.53; I2 = 41%) and DBP (MD -2.53 mmHg; 95% CI: -4.05 to -1.02; I2 = 65%). Potassium 21-30 selenium binding protein 1 Homo sapiens 101-104 28391629-20 2017 AUTHORS" CONCLUSIONS: Sodium reduction from an average high usual sodium intake level (201 mmol/day) to an average level of 66 mmol/day, which is below the recommended upper level of 100 mmol/day (5.8 g salt), resulted in a decrease in SBP/DBP of 1/0 mmHg in white participants with normotension and a decrease in SBP/DBP of 5.5/2.9 mmHg in white participants with hypertension. Sodium 22-28 selenium binding protein 1 Homo sapiens 236-239 28030431-3 2017 The primary assessment was the superiority of LCZ696/amlodipine versus amlodipine in lowering 24-h ambulatory SBP from baseline to week 8. Amlodipine 71-81 selenium binding protein 1 Homo sapiens 110-113 28030431-6 2017 At week 8, LCZ696/amlodipine provided greater reductions in 24-h SBP compared with amlodipine monotherapy from baseline (-13.9 versus -0.8 mmHg, P < 0.001). sacubitril and valsartan sodium hydrate drug combination 11-17 selenium binding protein 1 Homo sapiens 65-68 28030431-6 2017 At week 8, LCZ696/amlodipine provided greater reductions in 24-h SBP compared with amlodipine monotherapy from baseline (-13.9 versus -0.8 mmHg, P < 0.001). Amlodipine 18-28 selenium binding protein 1 Homo sapiens 65-68 28405118-5 2017 RESULTS: In the study group comprising of 50 cases of preeclampsia, there is a positive correlation (r = 0.695 & +0.359) between the variables in study group, and as the SBP or DBP increases, the MSUA concentration also increases. Adenosine Monophosphate 60-63 selenium binding protein 1 Homo sapiens 174-177 28405118-5 2017 RESULTS: In the study group comprising of 50 cases of preeclampsia, there is a positive correlation (r = 0.695 & +0.359) between the variables in study group, and as the SBP or DBP increases, the MSUA concentration also increases. msua 200-204 selenium binding protein 1 Homo sapiens 174-177 28422891-11 2017 The association between ambulatory SBP and CVD may be dependent on aldosterone excess. Aldosterone 67-78 selenium binding protein 1 Homo sapiens 35-38 28462075-12 2017 In men, 2-arachidonoylglycerol correlated with triglycerides in NW, OW (both P < 0.001), and OB (P = 0.029), with SBP (P = 0.023) and diastolic BP (DBP; P = 0.048) in OB, and with TC (P < 0.001) in OW class. glyceryl 2-arachidonate 8-30 selenium binding protein 1 Homo sapiens 117-120 27722961-15 2017 However, for patients with protein-creatinine ratio >500 mg/g (albumin-creatinine ratio > 300 mg/g), with or without diabetes, lower SBP target should be proposed for renal protection aiming SBP < 130 mmHg as recommended by KDIGO guidelines.In patients at low or intermediate risk, without cardiovascular disease, SBP should start to be treated when SBP is above 140 mmHg, and when treated, target BP should be less than 140 mmHg as reported by HOPE-3 trial. Creatinine 74-84 selenium binding protein 1 Homo sapiens 139-142 28236285-22 2017 CONCLUSIONS: Statistically significant pre-post increases of SBP, DBP and HR were associated with AMP and ATX treatment in children and adolescents with ADHD, while MPH treatment had a statistically significant effect only on SBP in these patients. Amphetamines 98-101 selenium binding protein 1 Homo sapiens 61-64 28236285-22 2017 CONCLUSIONS: Statistically significant pre-post increases of SBP, DBP and HR were associated with AMP and ATX treatment in children and adolescents with ADHD, while MPH treatment had a statistically significant effect only on SBP in these patients. Atomoxetine Hydrochloride 106-109 selenium binding protein 1 Homo sapiens 61-64 28762933-4 2017 According to the office BP measurements fixed combination perindopril+amlodipine provided the SBP reduction by 17.5%, 15.6%, 15, 6%, 15.5% and 17.7%, DBP reduction by 14.6%, 12.9%, 13.8%, respectively, in groups ACEI+D initial combination therapy, ACEI+AC initial combination therapy, ARB+D initial combination therapy, ARB+AC initial combination therapy. Perindopril 58-69 selenium binding protein 1 Homo sapiens 94-97 28762933-4 2017 According to the office BP measurements fixed combination perindopril+amlodipine provided the SBP reduction by 17.5%, 15.6%, 15, 6%, 15.5% and 17.7%, DBP reduction by 14.6%, 12.9%, 13.8%, respectively, in groups ACEI+D initial combination therapy, ACEI+AC initial combination therapy, ARB+D initial combination therapy, ARB+AC initial combination therapy. Amlodipine 70-80 selenium binding protein 1 Homo sapiens 94-97 28762933-6 2017 The fixed combination perindopril+amlodipine reduced PWV by 25.2%, 21.6%, 23.1%, 23.0%, augmentation index by 43.4%, 48.9%, 41.5%, 38.3%, central SBP by 16.1%, 15.5%, 14.4%, 15.2%, the central DBP by 15.1%, 13.8%, 13.8%, 18.0% (p<0.01 vs. baseline). Perindopril 22-33 selenium binding protein 1 Homo sapiens 146-149 28762933-6 2017 The fixed combination perindopril+amlodipine reduced PWV by 25.2%, 21.6%, 23.1%, 23.0%, augmentation index by 43.4%, 48.9%, 41.5%, 38.3%, central SBP by 16.1%, 15.5%, 14.4%, 15.2%, the central DBP by 15.1%, 13.8%, 13.8%, 18.0% (p<0.01 vs. baseline). Amlodipine 34-44 selenium binding protein 1 Homo sapiens 146-149 28208791-7 2017 A significant reduction was also observed in fasting plasma glucose (DM = -0.18 mmol/L; 95%CI: -0.29, -0.08), and in blood pressure (SBP: DM = -4.84 mmHg; 95% CI: -5.64, -4.04; DBP: DM = -3.32 mmHg; 95% CI: -4.09, -2.55). dm 140-142 selenium binding protein 1 Homo sapiens 135-138 28184244-3 2017 RESULTS: A silica-binding SBP sequence was fused genetically to three thermostable hemicellulases. Silicon Dioxide 11-17 selenium binding protein 1 Homo sapiens 26-29 28184244-9 2017 This technology exploited a silica-binding SBP to mediate effectively the rapid and simple immobilisation of thermostable enzymes onto readily-available and inexpensive silica-based matrices. Silicon Dioxide 28-34 selenium binding protein 1 Homo sapiens 43-46 28184244-9 2017 This technology exploited a silica-binding SBP to mediate effectively the rapid and simple immobilisation of thermostable enzymes onto readily-available and inexpensive silica-based matrices. Silicon Dioxide 169-175 selenium binding protein 1 Homo sapiens 43-46 27835032-10 2017 After adjusting for covariates, SBP and DBP and creatinine levels were independently associated with 24 hours urinary [Na+]/[K+] Conclusion: These findings suggest that pregnant with PE with high dietary salt and low potassium intake may have greater maternal and neonatal morbidity risk than pregnant with PE under low dietary salt and high potassium intake. Salts 204-208 selenium binding protein 1 Homo sapiens 32-35 27835032-10 2017 After adjusting for covariates, SBP and DBP and creatinine levels were independently associated with 24 hours urinary [Na+]/[K+] Conclusion: These findings suggest that pregnant with PE with high dietary salt and low potassium intake may have greater maternal and neonatal morbidity risk than pregnant with PE under low dietary salt and high potassium intake. Salts 328-332 selenium binding protein 1 Homo sapiens 32-35 27835032-10 2017 After adjusting for covariates, SBP and DBP and creatinine levels were independently associated with 24 hours urinary [Na+]/[K+] Conclusion: These findings suggest that pregnant with PE with high dietary salt and low potassium intake may have greater maternal and neonatal morbidity risk than pregnant with PE under low dietary salt and high potassium intake. Potassium 342-351 selenium binding protein 1 Homo sapiens 32-35 27193228-6 2017 Meanwhile, BP was reduced significantly by the SPB procedure (SBP: from 122.0 +- 13.4 to 114.2 +- 14.9 mmHg, p < 0.001, DBP: from 82.2 +- 8.6 to 77.0 +- 9.8 mmHg, p < 0.001, PTT: from 172.8 +- 20.1 to 176.8 +- 19.2 ms, p < 0.001). spb 47-50 selenium binding protein 1 Homo sapiens 62-65 28450950-4 2017 Valsartan treatment significantly reduced mean 24-h SBP/DBP (-6.1/-4.4 mmHg; both P<0.0001) and mean home-monitored SBP/DBP (-13.3/-9.1 mmHg; both P<0.0001) at week 10. Valsartan 0-9 selenium binding protein 1 Homo sapiens 52-55 28450950-4 2017 Valsartan treatment significantly reduced mean 24-h SBP/DBP (-6.1/-4.4 mmHg; both P<0.0001) and mean home-monitored SBP/DBP (-13.3/-9.1 mmHg; both P<0.0001) at week 10. Valsartan 0-9 selenium binding protein 1 Homo sapiens 119-122 27913606-5 2017 RESULTS: Compared to the saline control, AG and combined AG + DAG infusions decreased sBP, dBP, mean arterial blood pressure (MAP), HR and Temp. ghrelin, des-n-octanoyl 62-65 selenium binding protein 1 Homo sapiens 86-89 27931053-5 2017 Additionally, HI-RE showed higher SBP (4th set) and DBP (all sets) (P<0.05) values than the LI-RE. hi-re 14-19 selenium binding protein 1 Homo sapiens 34-37 27722961-15 2017 However, for patients with protein-creatinine ratio >500 mg/g (albumin-creatinine ratio > 300 mg/g), with or without diabetes, lower SBP target should be proposed for renal protection aiming SBP < 130 mmHg as recommended by KDIGO guidelines.In patients at low or intermediate risk, without cardiovascular disease, SBP should start to be treated when SBP is above 140 mmHg, and when treated, target BP should be less than 140 mmHg as reported by HOPE-3 trial. Creatinine 35-45 selenium binding protein 1 Homo sapiens 139-142 27662781-6 2017 TBiL level was negatively correlated with age, weight, SBP, TC, FBG, 2hPG, diabetic duration and positively correlated with HDL-C. Bilirubin 0-4 selenium binding protein 1 Homo sapiens 55-58 27600468-8 2017 Significant positive correlations were found between homocysteine and sBP (p=0.036), dBP (p=0.04), Apo B (p=0.038) and hyperlipoproteinemia (type IIa, type IIb and type IV) (p=0.04). Homocysteine 53-65 selenium binding protein 1 Homo sapiens 70-73 27712903-15 2017 A binomial logistic regression model adjusting for age, SBP <90, HR, and ISS >15 revealed ET CO2 < 35 to be independently predictive of CAT+ (OR 9.24, 95% CI 1.51-56.57, p=0.016). N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide 99-102 selenium binding protein 1 Homo sapiens 56-59 27775956-6 2017 RESULT: Annual change in SBP (standardized coefficient: 0.33, P < 0.001), but not its baseline level (standardized coefficient: 0.03, P = 0.495), had a positive significant association with the progression of baPWV after adjusting for a wide range of standard cardiovascular risk factors. bapwv 212-217 selenium binding protein 1 Homo sapiens 25-28 27906838-7 2017 For example, assuming beta0 = 7, an increase of SBP/DBP from 110/70 to 170/120 mmHg increased beta by 8.1% and CAVI by 14.3%. (2-benzoylethyl)trimethylammonium 22-26 selenium binding protein 1 Homo sapiens 48-51 27906839-7 2017 Bosentan suppressed completely the increase in SBP during a 5-min hypoxic challenge (143 +- 5 mmHg during hypoxia vs. 133 +- 5 mmHg during normoxia with placebo and 127 +- 3 mmHg during hypoxia vs. 125 +- 3 mmHg during normoxia under bosentan, P = 0.023). Bosentan 0-8 selenium binding protein 1 Homo sapiens 47-50 27906839-7 2017 Bosentan suppressed completely the increase in SBP during a 5-min hypoxic challenge (143 +- 5 mmHg during hypoxia vs. 133 +- 5 mmHg during normoxia with placebo and 127 +- 3 mmHg during hypoxia vs. 125 +- 3 mmHg during normoxia under bosentan, P = 0.023). Bosentan 234-242 selenium binding protein 1 Homo sapiens 47-50 28665768-3 2017 The aim of this study was to assess the sensitivity of urinary SBP1 levels as an early detection of AKI using animal models such as cisplatin or ischemia/reperfusion (I/R). Cisplatin 132-141 selenium binding protein 1 Homo sapiens 63-67 27759579-6 2017 RESULTS: The magnesium group had a significant reduction in SBP (144 +- 17 vs. 134 +- 14 mmHg, P = 0.036) and DBP (88 +- 9 vs. 81 +- 8 mmHg, P = 0.005) at 6 months, without effect on plasma glucose, lipids, or arterial stiffness parameters. Magnesium 13-22 selenium binding protein 1 Homo sapiens 60-63 28290816-14 2016 Change of LVMI after ALFDC treatment correlated with dynamics of 24-hour, daytime SBP, and daytime pulse pressure (r=0.382, p<0.05, r=0.478, p<0.01, and r=0.364, p<0.05, respectively). alfdc 21-26 selenium binding protein 1 Homo sapiens 82-85 27504853-7 2016 Amlodipine and valsartan monotherapy effects on SBP and DBP were best described by an Imax model with an effect compartment delay. Amlodipine 0-10 selenium binding protein 1 Homo sapiens 48-51 27504853-7 2016 Amlodipine and valsartan monotherapy effects on SBP and DBP were best described by an Imax model with an effect compartment delay. Valsartan 15-24 selenium binding protein 1 Homo sapiens 48-51 27504853-13 2016 CONCLUSION: PKPD models for SBP and DBP successfully described the time course of the antihypertensive effects of amlodipine and valsartan. Amlodipine 114-124 selenium binding protein 1 Homo sapiens 28-31 27504853-13 2016 CONCLUSION: PKPD models for SBP and DBP successfully described the time course of the antihypertensive effects of amlodipine and valsartan. Valsartan 129-138 selenium binding protein 1 Homo sapiens 28-31 27578024-8 2016 CONCLUSIONS: Empagliflozin combined with other oral treatments decreased HbA1c, body weight, and SBP/DBP as compared to placebo, with a good safety and tolerability profile. empagliflozin 13-26 selenium binding protein 1 Homo sapiens 97-100 27779457-10 2016 Overall, the lercanidipine/enalapril fixed-dose combination reduced SBP by 26 mmHg (95% CI, 23-29), and DBP by 13 mmHg (12-15), p < 0.05 for both. lercanidipine 13-26 selenium binding protein 1 Homo sapiens 68-71 28167482-6 2016 Metformin caused a significant reduction in blood pressure with p < 0.05 (i.e. SBP 9.9% & DBP 6.4%) while sitagliptin caused a highly significant p <0.01 reduction in blood pressure (i.e. SBP 15.8% & DBP 12.2%). Metformin 0-9 selenium binding protein 1 Homo sapiens 82-85 28167482-6 2016 Metformin caused a significant reduction in blood pressure with p < 0.05 (i.e. SBP 9.9% & DBP 6.4%) while sitagliptin caused a highly significant p <0.01 reduction in blood pressure (i.e. SBP 15.8% & DBP 12.2%). Metformin 0-9 selenium binding protein 1 Homo sapiens 198-201 27340146-10 2016 The largest change in SBP was seen with drinks administering >=200 mg of caffeine (6.44 mm Hg, 95% CI = 4.62 to 8.27). Caffeine 76-84 selenium binding protein 1 Homo sapiens 22-25 27648720-6 2016 Drinkers of at least 10 g of alcohol per day had 4.5 mmHg higher SBP than did nondrinkers. Alcohols 29-36 selenium binding protein 1 Homo sapiens 65-68 27720938-7 2016 Seven genes (FAM46C, IFITM3, GMPR, DENND6B, SELENBP1, NOL10, and SIAH2), involved in different pathways including regulatory, migratory, and signalling processes, were downregulated in PDAC patients with SR. Our results suggest the existence of a gene expression profiling significantly correlated with erlotinib-induced SR in PDAC that could be used as prognostic indicator in this patients. pdac 185-189 selenium binding protein 1 Homo sapiens 44-52 27809223-5 2016 Above the single sensor breakdown voltage, linear sensitivity dependence on the bias and the constant 3 dB bandwidth of the series connection enable increasing its SBP up to nearly 10,000 MHz V/T under 5 V. Thus, although by tuning bias voltage it is possible to control the sensitivity-bandwidth product, the choice between the single TMR sensor and the series connection is crucial for the optimal performance in the high frequency range. tmr 336-339 selenium binding protein 1 Homo sapiens 164-167 27779457-10 2016 Overall, the lercanidipine/enalapril fixed-dose combination reduced SBP by 26 mmHg (95% CI, 23-29), and DBP by 13 mmHg (12-15), p < 0.05 for both. Enalapril 27-36 selenium binding protein 1 Homo sapiens 68-71 25883097-3 2016 Results showed that occupational exposure to higher ambient Pb and noise levels was related to slightly increased SBP and DBP. Lead 60-62 selenium binding protein 1 Homo sapiens 114-117 27821918-4 2016 [Results] Significant differences in norepinephrine, cortisol and blood pressure (SBP & DBP) were found in terms of interaction by time interval and between groups. Norepinephrine 37-51 selenium binding protein 1 Homo sapiens 82-85 28290893-7 2016 RESULTS: Regardless of the regimen used azilsartan destination as part of combination therapy after 4 weeks showed a significant (p<0.05) reduction in SBP and DBP. azilsartan 40-50 selenium binding protein 1 Homo sapiens 154-157 28290893-10 2016 However, positive changes such indicators as an index time of hypertension in the day and night hours, SBP, DBP, and BP variability during the night, the morning rise of systolic as well as the speed of morning rise in SBP and DBP were more pronounced in the appointment azilsartan medoxomil at bedtime compared to morning reception. azilsartan 271-281 selenium binding protein 1 Homo sapiens 219-222 28290893-10 2016 However, positive changes such indicators as an index time of hypertension in the day and night hours, SBP, DBP, and BP variability during the night, the morning rise of systolic as well as the speed of morning rise in SBP and DBP were more pronounced in the appointment azilsartan medoxomil at bedtime compared to morning reception. medoxomil 282-291 selenium binding protein 1 Homo sapiens 219-222 25883097-4 2016 PbB values correlated significantly with SBP and DBP, whereas noise levels correlated neither with SBP nor with DBP. Polybrominated Biphenyls 0-3 selenium binding protein 1 Homo sapiens 41-44 27770523-18 2016 MBG and OU levels positively correlated with SBP in salt-sensitive individuals but salt-resistant subjects didn"t show any changes. Salts 52-56 selenium binding protein 1 Homo sapiens 45-48 27448942-5 2016 We found that KCl supplementation for 4 weeks induced a significant reduction in nighttime SBP compared with placebo (116 +- 12 vs 121 +- 15 mm Hg, respectively, p <0.01 vs placebo), whereas KMgCit and KCit had no significant effect in the same subjects (118 +- 11 and 119 +- 13 mm Hg, respectively, p >0.1 vs placebo). Potassium Chloride 14-17 selenium binding protein 1 Homo sapiens 91-94 27600499-7 2016 Compared with control (placebo, sitagliptin, glimepiride, dulaglutide, insulin glargine, and NPH), liraglutide in combination with metformin resulted in significant reductions in HbA1c, bodyweight, FPG, and PPG, and similar reductions in SBP, and DBP. Metformin 131-140 selenium binding protein 1 Homo sapiens 238-241 27327441-10 2016 CONCLUSION: We conclude that spironolactone is more effective than RDN to reduce 24-h SBP and 24-h DBP in patients with resistant hypertension. Spironolactone 29-43 selenium binding protein 1 Homo sapiens 86-89 27379537-9 2016 In multivariate regression analyses, with adjustment for age, sex, PTH, FGF-23, traditional cardiovascular risk factors, antihypertensive medication and parameters of calcium metabolism ARR remained significantly and directly related with nocturnal BP (SBP: adjusted beta-coefficient = 0.289, P < 0.01; DBP: beta = 0.399, P < 0.01). Calcium 167-174 selenium binding protein 1 Homo sapiens 253-256 27477809-0 2016 Sodium Selenite Inhibits Proliferation of Gastric Cancer Cells by Inducing SBP1 Expression. Sodium Selenite 0-15 selenium binding protein 1 Homo sapiens 75-79 27488551-6 2016 RESULTS: In selected participants (n = 320), SBP was positively correlated with BMI-SDS (r = 0.382, P < 0.001), HOMA-IR (r = 0.211, P < 0.001), MMP-9 activity (r = 0.215, P < 0.001) and the cortisol/cortisone ratio (r = 0.231, P < 0.001). bmi-sds 80-87 selenium binding protein 1 Homo sapiens 45-48 27488551-6 2016 RESULTS: In selected participants (n = 320), SBP was positively correlated with BMI-SDS (r = 0.382, P < 0.001), HOMA-IR (r = 0.211, P < 0.001), MMP-9 activity (r = 0.215, P < 0.001) and the cortisol/cortisone ratio (r = 0.231, P < 0.001). Hydrocortisone 199-207 selenium binding protein 1 Homo sapiens 45-48 27488551-6 2016 RESULTS: In selected participants (n = 320), SBP was positively correlated with BMI-SDS (r = 0.382, P < 0.001), HOMA-IR (r = 0.211, P < 0.001), MMP-9 activity (r = 0.215, P < 0.001) and the cortisol/cortisone ratio (r = 0.231, P < 0.001). Cortisone 208-217 selenium binding protein 1 Homo sapiens 45-48 26940214-8 2016 CONCLUSION: Our findings indicated that SBP and severity of BP profiles were significantly and independently associated with DCAN, respectively. dcan 125-129 selenium binding protein 1 Homo sapiens 40-43 27477809-9 2016 However, these effects of sodium selenite were attenuated in SGC7901 and N87 cells by knockdown of SBP1 expression. Sodium Selenite 26-41 selenium binding protein 1 Homo sapiens 99-103 27477809-10 2016 Thus, the sodium selenite-induced SBP1 expression is associated with the inhibition of cell proliferation and with the induced apoptosis. Sodium Selenite 10-25 selenium binding protein 1 Homo sapiens 34-38 27327441-7 2016 RESULTS: Spironolactone was more effective than RDN in reducing 24-h SBP and 24-h DBP: mean baseline-adjusted differences between the two groups were -17.9 mmHg (95%CI -30.9 to -4.9); P = 0.010 and -6.6 mmHg (95%CI -12.9 to -0.3); P = 0.041, for 24-h SBP and 24-h DBP, respectively. Spironolactone 9-23 selenium binding protein 1 Homo sapiens 69-72 27327441-7 2016 RESULTS: Spironolactone was more effective than RDN in reducing 24-h SBP and 24-h DBP: mean baseline-adjusted differences between the two groups were -17.9 mmHg (95%CI -30.9 to -4.9); P = 0.010 and -6.6 mmHg (95%CI -12.9 to -0.3); P = 0.041, for 24-h SBP and 24-h DBP, respectively. Spironolactone 9-23 selenium binding protein 1 Homo sapiens 251-254 27477809-2 2016 Selenium-binding protein 1 (SBP1) has been shown as a possible mediator of selenium"s anti-cancer functions. Selenium 75-83 selenium binding protein 1 Homo sapiens 0-26 27477809-2 2016 Selenium-binding protein 1 (SBP1) has been shown as a possible mediator of selenium"s anti-cancer functions. Selenium 75-83 selenium binding protein 1 Homo sapiens 28-32 27477809-8 2016 Furthermore, sodium selenite increased the expression level of SBP1 and decreased the levels of nuclear factor erythroid 2-related factor 2 (Nrf2) and the Wnt pathway components and its downstream targets, including beta-catenin, GSK-3beta, c-myc and cyclinD1 in these cell lines. Sodium Selenite 13-28 selenium binding protein 1 Homo sapiens 63-67 27089422-7 2016 A linear regression method was used to examine the association between water salinity exposure categories and systolic BP (SBP) and diastolic BP (DBP) level. Water 71-76 selenium binding protein 1 Homo sapiens 110-144 27402745-2 2016 The experimentally determined ligand specificities of several solute binding proteins (SBPs) for TRAP (tripartite ATP-independent permease) transporters for four-carbon acids, including d-erythronate and l-erythronate, were used to constrain the substrates for the catabolic pathways that degrade the SBP ligands to intermediates in central carbon metabolism. Adenosine Triphosphate 114-117 selenium binding protein 1 Homo sapiens 87-90 27402745-2 2016 The experimentally determined ligand specificities of several solute binding proteins (SBPs) for TRAP (tripartite ATP-independent permease) transporters for four-carbon acids, including d-erythronate and l-erythronate, were used to constrain the substrates for the catabolic pathways that degrade the SBP ligands to intermediates in central carbon metabolism. carbon acids 162-174 selenium binding protein 1 Homo sapiens 87-90 27402745-2 2016 The experimentally determined ligand specificities of several solute binding proteins (SBPs) for TRAP (tripartite ATP-independent permease) transporters for four-carbon acids, including d-erythronate and l-erythronate, were used to constrain the substrates for the catabolic pathways that degrade the SBP ligands to intermediates in central carbon metabolism. d-erythronate 186-199 selenium binding protein 1 Homo sapiens 87-90 27402745-2 2016 The experimentally determined ligand specificities of several solute binding proteins (SBPs) for TRAP (tripartite ATP-independent permease) transporters for four-carbon acids, including d-erythronate and l-erythronate, were used to constrain the substrates for the catabolic pathways that degrade the SBP ligands to intermediates in central carbon metabolism. L-erythronate 204-217 selenium binding protein 1 Homo sapiens 87-90 27402745-2 2016 The experimentally determined ligand specificities of several solute binding proteins (SBPs) for TRAP (tripartite ATP-independent permease) transporters for four-carbon acids, including d-erythronate and l-erythronate, were used to constrain the substrates for the catabolic pathways that degrade the SBP ligands to intermediates in central carbon metabolism. Carbon 162-168 selenium binding protein 1 Homo sapiens 87-90 27404728-1 2016 Selenium-binding protein 1 (SBP1) is not a selenoprotein but structurally binds selenium. Selenium 80-88 selenium binding protein 1 Homo sapiens 0-26 27404728-1 2016 Selenium-binding protein 1 (SBP1) is not a selenoprotein but structurally binds selenium. Selenium 80-88 selenium binding protein 1 Homo sapiens 28-32 27404728-3 2016 Because genome instability is a hallmark of cancer, we hypothesize that SBP1 sequesters cellular selenium and sensitizes cancer cells to DNA-damaging agents. Selenium 97-105 selenium binding protein 1 Homo sapiens 72-76 27404728-5 2016 Reduced sensitivity to hydrogen peroxide, paraquat and camptothecin, reactive oxygen species content, and intracellular retention of selenium after selenomethionine treatment were observed in SBP1 shRNA HeLa cells. Hydrogen Peroxide 23-40 selenium binding protein 1 Homo sapiens 192-196 27404728-5 2016 Reduced sensitivity to hydrogen peroxide, paraquat and camptothecin, reactive oxygen species content, and intracellular retention of selenium after selenomethionine treatment were observed in SBP1 shRNA HeLa cells. Paraquat 42-50 selenium binding protein 1 Homo sapiens 192-196 27404728-5 2016 Reduced sensitivity to hydrogen peroxide, paraquat and camptothecin, reactive oxygen species content, and intracellular retention of selenium after selenomethionine treatment were observed in SBP1 shRNA HeLa cells. Camptothecin 55-67 selenium binding protein 1 Homo sapiens 192-196 27404728-5 2016 Reduced sensitivity to hydrogen peroxide, paraquat and camptothecin, reactive oxygen species content, and intracellular retention of selenium after selenomethionine treatment were observed in SBP1 shRNA HeLa cells. Reactive Oxygen Species 69-92 selenium binding protein 1 Homo sapiens 192-196 27404728-5 2016 Reduced sensitivity to hydrogen peroxide, paraquat and camptothecin, reactive oxygen species content, and intracellular retention of selenium after selenomethionine treatment were observed in SBP1 shRNA HeLa cells. Selenium 133-141 selenium binding protein 1 Homo sapiens 192-196 27404728-5 2016 Reduced sensitivity to hydrogen peroxide, paraquat and camptothecin, reactive oxygen species content, and intracellular retention of selenium after selenomethionine treatment were observed in SBP1 shRNA HeLa cells. Selenomethionine 148-164 selenium binding protein 1 Homo sapiens 192-196 27404728-6 2016 Results from Western analyses showed that treatment of HeLa cells with selenomethionine resulted in increased SBP1 protein expression in a dose-dependent manner. Selenomethionine 71-87 selenium binding protein 1 Homo sapiens 110-114 27404728-8 2016 Altogether, SBP1 retains supplemental selenium and sensitizes HeLa cancer cells to clastogens, suggesting a new cancer treatment strategy by sequestering selenium through SBP1. Selenium 38-46 selenium binding protein 1 Homo sapiens 12-16 27404728-8 2016 Altogether, SBP1 retains supplemental selenium and sensitizes HeLa cancer cells to clastogens, suggesting a new cancer treatment strategy by sequestering selenium through SBP1. Selenium 154-162 selenium binding protein 1 Homo sapiens 12-16 27089422-9 2016 Multivariable linear regression analyses identified that compared to the low water salinity exposure category (<600 mg/L), those in the high water salinity category (>600 mg/L), had statistically significantly higher SBP (B 3.46, 95% CI 0.75, 6.17; p = 0.01) and DBP (B 2.77, 95% CI 0.31, 5.24; p = 0.03). Water 144-149 selenium binding protein 1 Homo sapiens 223-226 26223346-1 2016 A recent study from the United Kingdom indicates an association between pre hemodialysis (HD) serum sodium (SNa(+)) and systolic and diastolic blood pressure (SBP and DBP) in chronic HD patients. Sodium 100-106 selenium binding protein 1 Homo sapiens 159-162 26911233-10 2016 In simple correlation analyses, SBP and DBP were directly and significantly correlated with age, body mass index (BMI), blood glucose, hematocrit, plasma viscosity and blood viscosity. Blood Glucose 120-133 selenium binding protein 1 Homo sapiens 32-35 27136314-6 2016 RESULTS: The risk of developing hypertension was 47% and 73% greater for those in the fourth and fifth quintiles of triglycerides, after adjusting for age, sex, BMI, cigarette smoking, daily alcohol intake, lifestyle pattern, type 2 diabetes, antiaggregation therapy, low-density lipoprotein cholesterol, SBP, and DBP. Triglycerides 116-129 selenium binding protein 1 Homo sapiens 305-308 26875683-9 2016 Valsartan reduced SBP, DBP and CASP by 14.9 +- 10.7 mmHg, 10.9 +- 8.4 mmHg and 15.3 +- 10.9 mmHg, respectively (all p < 0.001). Valsartan 0-9 selenium binding protein 1 Homo sapiens 18-21 26290275-12 2016 Enalapril and atenolol are similarly effective in reducing SBP. Atenolol 14-22 selenium binding protein 1 Homo sapiens 59-62 27087421-6 2016 The results revealed that vitamin C, potassium, and calcium losses in sweat were positively correlated with systolic (SBP) and diastolic (DBP) blood pressure (all P<0.05). Ascorbic Acid 26-35 selenium binding protein 1 Homo sapiens 118-121 27087421-6 2016 The results revealed that vitamin C, potassium, and calcium losses in sweat were positively correlated with systolic (SBP) and diastolic (DBP) blood pressure (all P<0.05). Potassium 37-46 selenium binding protein 1 Homo sapiens 118-121 27087421-6 2016 The results revealed that vitamin C, potassium, and calcium losses in sweat were positively correlated with systolic (SBP) and diastolic (DBP) blood pressure (all P<0.05). Calcium 52-59 selenium binding protein 1 Homo sapiens 118-121 27087421-7 2016 A linear stepwise regression analysis revealed that potassium, and calcium losses in sweat adversely affected SBP and DBP (all P<0.05). Potassium 52-61 selenium binding protein 1 Homo sapiens 110-113 27087421-7 2016 A linear stepwise regression analysis revealed that potassium, and calcium losses in sweat adversely affected SBP and DBP (all P<0.05). Calcium 67-74 selenium binding protein 1 Homo sapiens 110-113 27087421-8 2016 An analysis of covariance showed that SBP increased when potassium or calcium losses in sweat were >900 mg, or >100 mg, respectively. Potassium 57-66 selenium binding protein 1 Homo sapiens 38-41 27087421-8 2016 An analysis of covariance showed that SBP increased when potassium or calcium losses in sweat were >900 mg, or >100 mg, respectively. Calcium 70-77 selenium binding protein 1 Homo sapiens 38-41 26290275-12 2016 Enalapril and atenolol are similarly effective in reducing SBP. Enalapril 0-9 selenium binding protein 1 Homo sapiens 59-62 27127102-8 2016 The mixed-model analysis showed that the changes in SBP were closely related to gender, indicating that the SBP-lowering effect after Val/Aml treatment might be better in women. val/aml 134-141 selenium binding protein 1 Homo sapiens 52-55 27027425-7 2016 The stabilization time of losartan for home SBP was significantly longer than that of valsartan, irbesartan, or azilsartan (22.8 vs. 7.1, 4.7, or 7.1 days, respectively, P <= 0.01). Losartan 26-34 selenium binding protein 1 Homo sapiens 44-47 26514661-4 2016 After adjusting for the base model, high frequency of alcohol drinking and high frequency of binge drinking remained significant for high SBP and DBP. Alcohols 54-61 selenium binding protein 1 Homo sapiens 138-141 27127102-8 2016 The mixed-model analysis showed that the changes in SBP were closely related to gender, indicating that the SBP-lowering effect after Val/Aml treatment might be better in women. val/aml 134-141 selenium binding protein 1 Homo sapiens 108-111 26766564-10 2016 Changes from baseline in 24-h or clinic SBP were significantly greater with AZL-M, 80 mg compared with either OLM 40 mg or VAL 320 mg in all subgroups in each pool. azilsartan medoxomil 76-81 selenium binding protein 1 Homo sapiens 40-43 27109832-9 2016 In addition, fasting glucose was negatively correlated with the decline rate of nocturnal SBP (r = -0.095, P = 0.029). Glucose 21-28 selenium binding protein 1 Homo sapiens 90-93 26938814-7 2016 RESULTS: The difference in SBP during 18 months of follow-up was 2.3 (95% confidence interval: 1.2 to 3.3) mmHg favoring chlorthalidone/amiloride. Chlorthalidone 121-135 selenium binding protein 1 Homo sapiens 27-30 26938814-7 2016 RESULTS: The difference in SBP during 18 months of follow-up was 2.3 (95% confidence interval: 1.2 to 3.3) mmHg favoring chlorthalidone/amiloride. Amiloride 136-145 selenium binding protein 1 Homo sapiens 27-30 26766564-10 2016 Changes from baseline in 24-h or clinic SBP were significantly greater with AZL-M, 80 mg compared with either OLM 40 mg or VAL 320 mg in all subgroups in each pool. olmesartan 110-113 selenium binding protein 1 Homo sapiens 40-43 26766564-12 2016 CONCLUSION: These analyses indicate that AZL-M, 80 mg/day lowers SBP by a greater magnitude than OLM or VAL at maximally approved doses in patients with prediabetes mellitus and T2DM. azilsartan medoxomil 41-46 selenium binding protein 1 Homo sapiens 65-68 27372528-12 2016 After multivariable adjustments, sodium intake was independently associated with SBP, but not DBP, in both sexes. Sodium 33-39 selenium binding protein 1 Homo sapiens 81-84 26778277-15 2016 When examined in this manner there was a reduction in both SBP (p <= 0.01) and mean arterial BP (p <= 0.05) from the antibacterial/chlorhexidine treatments. Chlorhexidine 137-150 selenium binding protein 1 Homo sapiens 59-62 27372528-14 2016 CONCLUSION: In a South Indian population, the dietary intake of sodium was higher than recommendations by major dietary guidelines and was an independent predictor of SBP. Sodium 64-70 selenium binding protein 1 Homo sapiens 167-170 27372528-8 2016 Mixed-effects multivariable linear regression models assessed the association of SBP and DBP with sodium intake. Sodium 98-104 selenium binding protein 1 Homo sapiens 81-84 26926184-7 2016 Importantly, some polyphenols also inhibit the activity of matrix metalloproteinases, inhibit angiotensin converting enzyme activity and thereby improving SBP and DSB. Polyphenols 18-29 selenium binding protein 1 Homo sapiens 155-158 27372528-11 2016 Significant (P < 0.01) increases in SBP and DBP were evident in men, but not women with increasing quintile of sodium intake. Sodium 114-120 selenium binding protein 1 Homo sapiens 39-42 26212138-8 2016 Stepwise linear regression analysis showed F-DEX% was significantly related to HbA1c level (beta=- 0.328, p=0.007) after adjusting for other covariates (age, BMI, waist circumference, SBP, TC, TG, and HOMA-IR). Fluorine 43-44 selenium binding protein 1 Homo sapiens 184-187 26212138-8 2016 Stepwise linear regression analysis showed F-DEX% was significantly related to HbA1c level (beta=- 0.328, p=0.007) after adjusting for other covariates (age, BMI, waist circumference, SBP, TC, TG, and HOMA-IR). Dextromethorphan 45-48 selenium binding protein 1 Homo sapiens 184-187 26957239-11 2016 In further mediation analysis for female participants, fasting insulin level/HOMA-IR/HOMA-%S played mediation roles in the relation between PBF and SBP, with ratio of mediation of 13.78%,18.3%, and 5.98%. L-4-Benzoylphenylalanine 140-143 selenium binding protein 1 Homo sapiens 148-151 26880195-8 2016 The largest alteration of SBP related to the temperature difference was observed from 20.4 to 9.6 C, with 9.0 mmHg (95 % CI: 8.4, 9.5) increase in SBP, while the largest alteration of DBP was observed from 21.7 to 10.2 C, with 6.1 mmHg (95 % CI: 5.6, 6.6) increase in DBP. Diosmin 185-188 selenium binding protein 1 Homo sapiens 26-29 26880195-8 2016 The largest alteration of SBP related to the temperature difference was observed from 20.4 to 9.6 C, with 9.0 mmHg (95 % CI: 8.4, 9.5) increase in SBP, while the largest alteration of DBP was observed from 21.7 to 10.2 C, with 6.1 mmHg (95 % CI: 5.6, 6.6) increase in DBP. Diosmin 270-273 selenium binding protein 1 Homo sapiens 26-29 26882301-1 2016 In resistant hypertension, add-on spironolactone reduced SBP more than placebo, doxazosin, or bisoprolol over 12 wk. Spironolactone 34-48 selenium binding protein 1 Homo sapiens 57-60 26867060-7 2016 Office SBP and pulse pressure were significantly lower in both groups after 24 weeks of treatment and 48 h after the missed dose, observing a trend to greater SBP reduction in the olmesartan/amlodipine group. olmesartan 180-190 selenium binding protein 1 Homo sapiens 159-162 26867060-7 2016 Office SBP and pulse pressure were significantly lower in both groups after 24 weeks of treatment and 48 h after the missed dose, observing a trend to greater SBP reduction in the olmesartan/amlodipine group. Amlodipine 191-201 selenium binding protein 1 Homo sapiens 159-162 26808317-8 2016 SA had lower SBP than EU(-4.57 mmHg, 95% CI -6.20 to -2.93; -2.97 mmHg, 95% CI -5.45 to -0.49) but similar DBP values. 2-chloro-10-(4'(N-beta-hydroxyethyl)piperazinyl-1')acetylphenothiazine 0-2 selenium binding protein 1 Homo sapiens 13-16 26682780-7 2016 After adjustment for sex, age, BMI, physical activity, addition of salt to food, and education of the head of the family, SBP was 5.4 mmHg higher in the diet soft drink consumers group compared with the nonconsumers group and 3.3 mmHg higher compared with the sugar-sweetened consumers group (P value of trend = 0.01). Sugars 260-265 selenium binding protein 1 Homo sapiens 122-125 26675774-3 2016 OBJECTIVE: The aim was to assess the causal influence of homocysteine on systolic and diastolic blood pressure (SBP and DBP, respectively) in adults with the use of Mendelian randomization (MR). Homocysteine 57-69 selenium binding protein 1 Homo sapiens 112-115 26784948-10 2016 SBP/DBP increased with VAI and BFP increasing. vai 23-26 selenium binding protein 1 Homo sapiens 0-3 26784948-10 2016 SBP/DBP increased with VAI and BFP increasing. 2-benzyl-3-formylpropanoic acid 31-34 selenium binding protein 1 Homo sapiens 0-3 26675774-6 2016 The association of homocysteine concentration with SBP and DBP was assessed by conventional ordinary least-squares (OLS) linear regression and 2-stage least-squares (2SLS) regression (MR analysis). Homocysteine 19-31 selenium binding protein 1 Homo sapiens 51-54 26675774-9 2016 RESULTS: In OLS regression, a 1-SD unit increase in log homocysteine concentration was associated with an increase of 0.9 (95% CI: 0.4, 1.4) mm Hg in SBP and of 1.0 (95% CI: 0.6, 1.4) mm Hg in DBP. Homocysteine 56-68 selenium binding protein 1 Homo sapiens 150-153 26675774-10 2016 In 2SLS regression, for the same increase in homocysteine, the coefficients were -1.8 mm Hg for SBP (95% CI: -3.9, 0.4 mm Hg; P = 0.01) and 0.1 mm Hg for DBP (95% CI: -1.5, 1.7 mm Hg; P = 0.24). 2sls 3-7 selenium binding protein 1 Homo sapiens 96-99 26675774-10 2016 In 2SLS regression, for the same increase in homocysteine, the coefficients were -1.8 mm Hg for SBP (95% CI: -3.9, 0.4 mm Hg; P = 0.01) and 0.1 mm Hg for DBP (95% CI: -1.5, 1.7 mm Hg; P = 0.24). Homocysteine 45-57 selenium binding protein 1 Homo sapiens 96-99 27936961-10 2016 Maximum oxygen intake (beta = -0.193, P = 0.003) and resting SBP correlated with SBP after 10 years. Oxygen 8-14 selenium binding protein 1 Homo sapiens 81-84 26468286-3 2015 To assess the function of this putative accessory factor (AztD) from Paracoccus denitrificans, we have analyzed its transcriptional regulation, metal binding properties, and interaction with the SBP (AztC). aztc 200-204 selenium binding protein 1 Homo sapiens 195-198 26742700-5 2016 Although no significant change in renal function was noted in either group, there was a significant improvement in AI only in the benidipine group (85.7 +- 13.3% to 81.4 +- 15.2%; P = 0.021) A subgroup analysis of 64 patients who achieved SBP < 140 mmHg at the end of follow-up (31 on amlodipine and 33 on benidipine) was carried out. benidipine 130-140 selenium binding protein 1 Homo sapiens 239-242 26176708-5 2016 The addition of HCTZ 25 mg significantly reduced SeDBP (-2.8 mm Hg; P<.0001), lowered seated systolic BP (SeSBP) and ambulatory DBP and SBP, and improved BP goal rates. Hydrochlorothiazide 16-20 selenium binding protein 1 Homo sapiens 111-114 27924804-8 2016 Creatinine clearance (OR = 0.99, 95% CI = 0.98-0.10, P = 0.01) was associated with SBP in patients with CKD. Creatinine 0-10 selenium binding protein 1 Homo sapiens 83-86 26667723-10 2015 VAI markedly associated with TG, HDL-C, FSG, SBP and DBP or WHR, WC, WHtR and BMI in respective order of correlation potency for cardiometabolic or adiposity risk indices. vai 0-3 selenium binding protein 1 Homo sapiens 45-48 26378686-9 2015 The estimated increases in SBP and DBP were 4.9 mmHg [95% confidence interval (CI) 2.9-6.8] and 3.7 mmHg (95% CI 2.3-5.1) at high elemental carbon level (>=median), and were -1.3 mmHg (95% CI -6.3 to 3.6) and 0.7 mmHg (95% CI -2.8 to 4.2) at low elemental carbon level (<median) per 10 C decrease in daily minimum temperature. Carbon 140-146 selenium binding protein 1 Homo sapiens 27-30 26378686-9 2015 The estimated increases in SBP and DBP were 4.9 mmHg [95% confidence interval (CI) 2.9-6.8] and 3.7 mmHg (95% CI 2.3-5.1) at high elemental carbon level (>=median), and were -1.3 mmHg (95% CI -6.3 to 3.6) and 0.7 mmHg (95% CI -2.8 to 4.2) at low elemental carbon level (<median) per 10 C decrease in daily minimum temperature. Carbon 259-265 selenium binding protein 1 Homo sapiens 27-30 26517916-3 2015 Most prokaryotes have many SBP-dependent ABC transporters that recognize a broad range of ligands from metal ions to amino acids, sugars and peptides. Metals 103-108 selenium binding protein 1 Homo sapiens 27-30 26587408-8 2015 RESULTS: Variations in the HR, DBP and SaO2, in the specified time intervals, did not show any statistically significant difference, although variations in SBP were statistically significant (higher in gabapentin group). Gabapentin 202-212 selenium binding protein 1 Homo sapiens 156-159 26593911-0 2015 A Critical Role for Cysteine 57 in the Biological Functions of Selenium Binding Protein-1. Cysteine 20-28 selenium binding protein 1 Homo sapiens 63-89 26593911-2 2015 SBP1 binds tightly selenium although what role selenium plays in its biological functions remains unknown. Selenium 19-27 selenium binding protein 1 Homo sapiens 0-4 26593911-4 2015 In order to investigate the role of cysteine 57 in SBP1, this amino acid was altered to a glycine and the mutated protein was expressed in human cancer cells. Cysteine 36-44 selenium binding protein 1 Homo sapiens 51-55 26593911-6 2015 The ectopic expression of SBP1(GLY) also caused mitochondrial damage in HCT116 cells. Glycine 31-34 selenium binding protein 1 Homo sapiens 26-30 26593911-7 2015 Taken together, these results indicated that cysteine 57 is a critical determinant of SBP1 function and may play a significant role in mitochondrial function. Cysteine 45-53 selenium binding protein 1 Homo sapiens 86-90 26517916-3 2015 Most prokaryotes have many SBP-dependent ABC transporters that recognize a broad range of ligands from metal ions to amino acids, sugars and peptides. Sugars 130-136 selenium binding protein 1 Homo sapiens 27-30 26517916-3 2015 Most prokaryotes have many SBP-dependent ABC transporters that recognize a broad range of ligands from metal ions to amino acids, sugars and peptides. Peptides 141-149 selenium binding protein 1 Homo sapiens 27-30 26517916-4 2015 Herein, we review the structure and function of a number of more unusual SBPs, including an ABC transporter involved in the transport of rare furanose forms of sugars and an SBP that has evolved to specifically recognize the bacterial cell wall-derived murein tripeptide (Mtp). furanose 142-150 selenium binding protein 1 Homo sapiens 73-76 26517916-4 2015 Herein, we review the structure and function of a number of more unusual SBPs, including an ABC transporter involved in the transport of rare furanose forms of sugars and an SBP that has evolved to specifically recognize the bacterial cell wall-derived murein tripeptide (Mtp). Sugars 160-166 selenium binding protein 1 Homo sapiens 73-76 26517916-4 2015 Herein, we review the structure and function of a number of more unusual SBPs, including an ABC transporter involved in the transport of rare furanose forms of sugars and an SBP that has evolved to specifically recognize the bacterial cell wall-derived murein tripeptide (Mtp). tripeptide K-26 260-270 selenium binding protein 1 Homo sapiens 73-76 26123527-11 2015 There was a secondary, norepinephrine independent SBP rise in patients with severe global vasospasm that significantly correlated with the initial Hijdra-scale and an unfavorable clinical outcome. Norepinephrine 23-37 selenium binding protein 1 Homo sapiens 50-53 26431193-7 2015 In treated hypertensive patients, higher baseline serum phosphate was significantly associated with poor longitudinal SBP reduction (one standard deviation increase in phosphate was associated with 0.22 and 0.59 mmHg higher SBP at 5 years in men and women, respectively). Phosphates 56-65 selenium binding protein 1 Homo sapiens 118-121 26066644-6 2015 VVV of SBP was smaller in the olmesartan along with CCB group than in the olmesartan along with diuretic group, especially in very elderly patients and also isolated systolic hypertensive patients. olmesartan 30-40 selenium binding protein 1 Homo sapiens 7-10 26066644-6 2015 VVV of SBP was smaller in the olmesartan along with CCB group than in the olmesartan along with diuretic group, especially in very elderly patients and also isolated systolic hypertensive patients. olmesartan 74-84 selenium binding protein 1 Homo sapiens 7-10 26431193-7 2015 In treated hypertensive patients, higher baseline serum phosphate was significantly associated with poor longitudinal SBP reduction (one standard deviation increase in phosphate was associated with 0.22 and 0.59 mmHg higher SBP at 5 years in men and women, respectively). Phosphates 168-177 selenium binding protein 1 Homo sapiens 118-121 26049382-5 2015 Despite lower risks of metabolic side-effects, meta-analysis of clinical trials showed that, for any given difference in achieved clinic SBP, HCTZ therapy was associated with 18% higher adverse cardiovascular events when compared with CTD. Hydrochlorothiazide 142-146 selenium binding protein 1 Homo sapiens 137-140 26652987-6 2015 RESULTS: The sitting SBP was similarly decreased by (19.9 +- 17.2) mmHg in perindopril arginine group and (18.5 +- 14.7) mmHg (P = 0.000 5) in perindopril tert-butylamine group post 8 weeks treatment. Perindopril arginine 75-95 selenium binding protein 1 Homo sapiens 21-24 26406477-1 2015 To extend and improve the utility of the streptavidin-binding peptide tag (SBP-tag) in applications ranging from affinity purification to the reversible immobilization of recombinant proteins, a cysteine residue was introduced to the streptavidin mutein SAVSBPM18 and the SBP-tag to generate SAVSBPM32 and SBP(A18C), respectively. Cysteine 195-203 selenium binding protein 1 Homo sapiens 75-78 26406477-1 2015 To extend and improve the utility of the streptavidin-binding peptide tag (SBP-tag) in applications ranging from affinity purification to the reversible immobilization of recombinant proteins, a cysteine residue was introduced to the streptavidin mutein SAVSBPM18 and the SBP-tag to generate SAVSBPM32 and SBP(A18C), respectively. Cysteine 195-203 selenium binding protein 1 Homo sapiens 257-260 26406477-1 2015 To extend and improve the utility of the streptavidin-binding peptide tag (SBP-tag) in applications ranging from affinity purification to the reversible immobilization of recombinant proteins, a cysteine residue was introduced to the streptavidin mutein SAVSBPM18 and the SBP-tag to generate SAVSBPM32 and SBP(A18C), respectively. Cysteine 195-203 selenium binding protein 1 Homo sapiens 306-310 26406477-3 2015 SAVSBPM32 binds SBP-tag and biotin with binding affinities (Kd ~ 10-8M) that are similar to SAVSBPM18. Biotin 28-34 selenium binding protein 1 Homo sapiens 3-6 26406477-4 2015 Although SBP(A18C) binds to SAVSBPM32 more weakly than SBP-tag, the binding affinity is sufficient to bring the two binding partners together efficiently before they are locked together via disulfide bond formation-a phenomenon we have named affinity-driven thiol coupling. Disulfides 190-199 selenium binding protein 1 Homo sapiens 9-13 26406477-4 2015 Although SBP(A18C) binds to SAVSBPM32 more weakly than SBP-tag, the binding affinity is sufficient to bring the two binding partners together efficiently before they are locked together via disulfide bond formation-a phenomenon we have named affinity-driven thiol coupling. Disulfides 190-199 selenium binding protein 1 Homo sapiens 9-12 26406477-4 2015 Although SBP(A18C) binds to SAVSBPM32 more weakly than SBP-tag, the binding affinity is sufficient to bring the two binding partners together efficiently before they are locked together via disulfide bond formation-a phenomenon we have named affinity-driven thiol coupling. Sulfhydryl Compounds 258-263 selenium binding protein 1 Homo sapiens 9-13 26406477-4 2015 Although SBP(A18C) binds to SAVSBPM32 more weakly than SBP-tag, the binding affinity is sufficient to bring the two binding partners together efficiently before they are locked together via disulfide bond formation-a phenomenon we have named affinity-driven thiol coupling. Sulfhydryl Compounds 258-263 selenium binding protein 1 Homo sapiens 9-12 26406477-6 2015 The stoichiometry of the disulfide-bonded SAVSBPM32-SBP(A18C) complex was determined using a novel two-dimensional electrophoresis method which has general applications for analyzing the composition of disulfide-bonded protein complexes. Disulfides 25-34 selenium binding protein 1 Homo sapiens 45-48 26406477-6 2015 The stoichiometry of the disulfide-bonded SAVSBPM32-SBP(A18C) complex was determined using a novel two-dimensional electrophoresis method which has general applications for analyzing the composition of disulfide-bonded protein complexes. Disulfides 202-211 selenium binding protein 1 Homo sapiens 45-48 26296869-10 2015 Waist circumference, glucose, and triglycerides were positively and significantly associated with SBP and DBP during menopause. Glucose 21-28 selenium binding protein 1 Homo sapiens 98-101 26296869-10 2015 Waist circumference, glucose, and triglycerides were positively and significantly associated with SBP and DBP during menopause. Triglycerides 34-47 selenium binding protein 1 Homo sapiens 98-101 26039623-6 2015 Potassium supplementation resulted in reduction of SBP by 4.7 mmHg [95% confidence interval (CI) 2.4-7.0] and DBP by 3.5 mmHg (95% CI 1.3-5.7) in all patients. Potassium 0-9 selenium binding protein 1 Homo sapiens 51-54 26254276-6 2015 Further, the addition of spironolactone significantly reduced EOT in-office, 24-hour, and daytime systolic and diastolic blood pressure (SBP and DBP, respectively) and led to significantly greater reductions from baseline in in-office SBP and DBP, although it did not significantly affect nighttime SBP or DBP. Spironolactone 25-39 selenium binding protein 1 Homo sapiens 137-140 26254276-6 2015 Further, the addition of spironolactone significantly reduced EOT in-office, 24-hour, and daytime systolic and diastolic blood pressure (SBP and DBP, respectively) and led to significantly greater reductions from baseline in in-office SBP and DBP, although it did not significantly affect nighttime SBP or DBP. Spironolactone 25-39 selenium binding protein 1 Homo sapiens 235-238 26254276-6 2015 Further, the addition of spironolactone significantly reduced EOT in-office, 24-hour, and daytime systolic and diastolic blood pressure (SBP and DBP, respectively) and led to significantly greater reductions from baseline in in-office SBP and DBP, although it did not significantly affect nighttime SBP or DBP. Spironolactone 25-39 selenium binding protein 1 Homo sapiens 235-238 25944854-2 2015 The ASSERTIVE study previously reported more sustained control of Br-SBP with aliskiren versus telmisartan in patients with hypertension, following 7-days treatment withdrawal. aliskiren 78-87 selenium binding protein 1 Homo sapiens 69-72 25944854-9 2015 CONCLUSIONS: Following treatment withdrawal, aliskiren demonstrated more sustained control of both brachial and central SBP than telmisartan. aliskiren 45-54 selenium binding protein 1 Homo sapiens 120-123 25441094-8 2015 The combination AHT-DF produced an additional and significant reduction in (i) SBP/DBP of -5/-4 mmHg, being -7/-5 for Cpr + DF and -4/-3 for Tms + DF; (ii) triglyceride levels (-30.6%) versus AHT alone (-9.6%); and (iii) leptin: Cpr + DF versus Tms + DF (p < 0.005). aht-df 16-22 selenium binding protein 1 Homo sapiens 79-82 25441094-8 2015 The combination AHT-DF produced an additional and significant reduction in (i) SBP/DBP of -5/-4 mmHg, being -7/-5 for Cpr + DF and -4/-3 for Tms + DF; (ii) triglyceride levels (-30.6%) versus AHT alone (-9.6%); and (iii) leptin: Cpr + DF versus Tms + DF (p < 0.005). Captopril 118-121 selenium binding protein 1 Homo sapiens 79-82 25441094-8 2015 The combination AHT-DF produced an additional and significant reduction in (i) SBP/DBP of -5/-4 mmHg, being -7/-5 for Cpr + DF and -4/-3 for Tms + DF; (ii) triglyceride levels (-30.6%) versus AHT alone (-9.6%); and (iii) leptin: Cpr + DF versus Tms + DF (p < 0.005). Anhydrothymidine 16-19 selenium binding protein 1 Homo sapiens 79-82 26236105-2 2015 Key study results were as follows: First, serum 25-hydroxyvitamin D [25(OH)D] levels decreased significantly with an increase in MSS (p = 0.004), shown by serum 25(OH)D levels after adjusting the variables (age, gender, BMI, TC, HDL-C, FBS, SBP, and DBP, etc.). 25-hydroxyvitamin D 48-67 selenium binding protein 1 Homo sapiens 241-244 25962494-11 2015 In a multivariate model, after adjusting for ACEIs/ARBs discontinuation/dose reduction, NSAIDs use and change in DBP, an increase in SBP at time 1 remained significantly associated with increments in GFR on follow-up (estimate = 0.20, p = 0.01). aceis 45-50 selenium binding protein 1 Homo sapiens 133-136 25827430-7 2015 For example, one standard deviation higher log-UAGT/Cr ratio (1.2 mug/g) was associated with a 5.0-mmHg (95% confidence interval 2.3-7.8) higher SBP at the end of the high-sodium intervention, after adjusting for multiple covariates (P = 0.003). Chromium 52-54 selenium binding protein 1 Homo sapiens 146-149 25827430-7 2015 For example, one standard deviation higher log-UAGT/Cr ratio (1.2 mug/g) was associated with a 5.0-mmHg (95% confidence interval 2.3-7.8) higher SBP at the end of the high-sodium intervention, after adjusting for multiple covariates (P = 0.003). Sodium 173-179 selenium binding protein 1 Homo sapiens 146-149 25827430-8 2015 In addition, one standard deviation higher log-UAGT/Cr ratio was associated with a 1.6-mmHg increase in age-adjusted and sex-adjusted SBP from the low-sodium intervention to the high-sodium intervention (95% confidence interval 0.1-3.1, P = 0.04). Chromium 52-54 selenium binding protein 1 Homo sapiens 134-137 25827430-8 2015 In addition, one standard deviation higher log-UAGT/Cr ratio was associated with a 1.6-mmHg increase in age-adjusted and sex-adjusted SBP from the low-sodium intervention to the high-sodium intervention (95% confidence interval 0.1-3.1, P = 0.04). Sodium 151-157 selenium binding protein 1 Homo sapiens 134-137 25619683-5 2015 RESULTS: In boys, we found an inverse association between protein (animal and vegetable) intake and DBP; and a positive association between histidine and SBP. Histidine 140-149 selenium binding protein 1 Homo sapiens 154-157 25754396-6 2015 The LSM SBP decreased by -3.4 to -4.0 mmHg from baseline with ertugliflozin 5-25 mg/day. ertugliflozin 62-75 selenium binding protein 1 Homo sapiens 8-11 25619683-7 2015 On the other hand, we observed an inverse association between tyrosine and both SBP and DBP levels in girls. Tyrosine 62-70 selenium binding protein 1 Homo sapiens 80-83 25619683-6 2015 In girls, we observed a positive association among tryptophan, histidine with SBP and methionine with DBP. Histidine 63-72 selenium binding protein 1 Homo sapiens 78-81 26084324-10 2015 Also, these data suggest that ATW can elicit clinically meaningful reductions in DBP and night-time SBP. atw 30-33 selenium binding protein 1 Homo sapiens 100-103 25669316-7 2015 Systolic and diastolic BP (SBP and DBP, respectively) significantly increased from the lower to the higher tertile of sodium from snacks and with increasing frequency of salty snacks consumption. Sodium 118-124 selenium binding protein 1 Homo sapiens 27-30 25669316-9 2015 In the 400 individuals, the average total sodium intake was 3.1 g/day and was significantly higher in individuals belonging to the highest quartile of SBP and DBP. Sodium 42-48 selenium binding protein 1 Homo sapiens 151-154 25695618-0 2015 TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives. Hydrochlorothiazide 44-63 selenium binding protein 1 Homo sapiens 28-31 25695618-5 2015 TET2 and CSMD1 as plausible candidate genes to affect SBP response to hydrochlorothiazide were identified. Hydrochlorothiazide 70-89 selenium binding protein 1 Homo sapiens 54-57 25695618-9 2015 CONCLUSION: This exploratory study reports two plausible loci associated with SBP response to hydrochlorothiazide: TET2, an aldosterone-responsive mediator of alphaENaC gene transcription; and CSMD1, previously described as associated with hypertension in a case-control study. Hydrochlorothiazide 94-113 selenium binding protein 1 Homo sapiens 78-81 25735400-5 2015 RESULTS: At 208 weeks, dapagliflozin compared with glipizide produced sustained reductions in glycated haemoglogin (HbA1c): -0.30% [95% confidence interval (CI), -0.51 to -0.09], in total body weight: -4.38 kg (95% CI -5.31 to -3.46) and in systolic blood pressure (SBP): -3.67 mmHg (95% CI -5.92 to -1.41). dapagliflozin 23-36 selenium binding protein 1 Homo sapiens 241-274 25735400-10 2015 CONCLUSIONS: In patients completing 4 years of treatment, dapagliflozin was well tolerated and associated with sustained glycaemic efficacy and greater reductions in body weight and SBP versus glipizide. dapagliflozin 58-71 selenium binding protein 1 Homo sapiens 182-185 25993660-8 2015 Inducible ectopic SBP1 expression reduced the ability of HCT-116 human tumor cells to grow in soft agar, a measure of transformation, without affecting proliferation. Agar 99-103 selenium binding protein 1 Homo sapiens 18-22 25993660-9 2015 Cells expressing SBP1 also demonstrated a robust induction in the phosphorylation of the p53 tumor suppressor at serine 15. Serine 113-119 selenium binding protein 1 Homo sapiens 17-21 25753602-9 2015 RESULTS: Des-acyl ghrelin showed significant inverse correlations with almost all BPs except Morning SBP, Morning DBP, and Home DBP. ghrelin, des-n-octanoyl 9-25 selenium binding protein 1 Homo sapiens 101-104 25956918-12 2015 Nifedipine GITS combination treatment provided mean SBP/DBP changes of -36.1/-18.8 mm Hg in all patients, -40.2/-21.5 mm Hg in previously untreated patients, and -35.6/-18.4 mm Hg in previously treated patients, with similar BP reductions irrespective of the number of concomitant diseases. Nifedipine 0-10 selenium binding protein 1 Homo sapiens 52-55 25956918-15 2015 CONCLUSIONS: Combination therapy with nifedipine GITS in a real-life observational setting was highly effective in reducing SBP/DBP in a range of hypertensive patients, with low rates of treatment-related AEs. Nifedipine 38-48 selenium binding protein 1 Homo sapiens 124-127 25753602-10 2015 In multiple regression analysis, des-acyl ghrelin inversely correlated with Work SBP after adjusting for confounding factors. ghrelin, des-n-octanoyl 33-49 selenium binding protein 1 Homo sapiens 81-84 25350782-8 2015 CONCLUSION: The findings of the study showed that the weekly administration of 50 000 IU of oral vitamin D for 8 weeks as an adjunct supplement of antihypertensive drugs in patients with vitamin D deficiency could help prevent vitamin D deficiency and aid control of SBP, DBP, and MAP. Vitamin D 97-106 selenium binding protein 1 Homo sapiens 267-270 25326542-7 2015 Interquartile increases in black carbon (BC), fine particulate matter (PM10 and PMcoarse), UFP, and nitric oxides (NOx) were associated with statistically significantly higher SBP post-exposure (1.2, 1.0, 1.1, and 1.1 mm/Hg, respectively). Carbon 33-39 selenium binding protein 1 Homo sapiens 176-179 25326542-7 2015 Interquartile increases in black carbon (BC), fine particulate matter (PM10 and PMcoarse), UFP, and nitric oxides (NOx) were associated with statistically significantly higher SBP post-exposure (1.2, 1.0, 1.1, and 1.1 mm/Hg, respectively). Nitric Oxide 100-113 selenium binding protein 1 Homo sapiens 176-179 25326542-7 2015 Interquartile increases in black carbon (BC), fine particulate matter (PM10 and PMcoarse), UFP, and nitric oxides (NOx) were associated with statistically significantly higher SBP post-exposure (1.2, 1.0, 1.1, and 1.1 mm/Hg, respectively). Nitric Oxide 115-118 selenium binding protein 1 Homo sapiens 176-179 25997037-7 2015 Higher UA concentrations were associated with higher SBP levels only in overweight/obese women (beta = 3.878; 95% CI: 0.687-7.068), whereas higher CRP concentrations (>=2.6 mg/L) were associated with higher DBP in under/normal weight women (beta =2.252; 95% CI: 0.267-4.236).ALP, ALT, and Cr concentrations were positively associated with BP levels, whereas ALP was associated with a lower rate of change in BP. Uric Acid 7-9 selenium binding protein 1 Homo sapiens 53-56 25740261-4 2015 RESULTS: Individuals with a lower baseline XOR-mRNA expression showed lower plasma XOR activity and significantly greater changes in SBP (DeltaSBP) after IS-5-MN administration. Iodine 154-156 selenium binding protein 1 Homo sapiens 133-136 25958714-11 2015 CONCLUSION: Induction with propofol by effective site concentration of eight mcg/ml significantly decreased SBP more than with 8% sevoflurane. Propofol 27-35 selenium binding protein 1 Homo sapiens 108-111 25781947-8 2015 Multiple linear regression analysis showed that the change in ba-PWV was independently and positively associated with changes in L-octanoylcarnitine, lactosylceramide, and SBP, and with baseline BMI. ba-pwv 62-68 selenium binding protein 1 Homo sapiens 172-175 26685501-7 2015 CONCLUSION: The increase in HR and SBP in the luteal phase could be because increased water and salt retention due to the ovarian steroids. Water 86-91 selenium binding protein 1 Homo sapiens 35-38 26685501-7 2015 CONCLUSION: The increase in HR and SBP in the luteal phase could be because increased water and salt retention due to the ovarian steroids. Salts 96-100 selenium binding protein 1 Homo sapiens 35-38 26685501-7 2015 CONCLUSION: The increase in HR and SBP in the luteal phase could be because increased water and salt retention due to the ovarian steroids. Steroids 130-138 selenium binding protein 1 Homo sapiens 35-38 25861425-6 2015 A reduction of 28 mmol sodium excretion decreased SBP/DBP to 135.5 (+- 13.0)/82.5 (+- 12.8) (P < 0.001). Sodium 23-29 selenium binding protein 1 Homo sapiens 50-53 25471235-8 2015 Similarly, variability in SBP showed a significant negative association with flow-mediated dilation, independent of age, eGFR, HbA1c, LDL cholesterol and M SBP. Cholesterol 138-149 selenium binding protein 1 Homo sapiens 26-29 25481367-3 2015 Consumption of 5 mg/kg caffeine had an impact on participants" SBP, standard deviation of normal heartbeat intervals, HR (decrease), and subjective experience 40 minutes later even after controlling for respective baseline values, stimulus and response expectancies, and habitual caffeine consumption. Caffeine 23-31 selenium binding protein 1 Homo sapiens 63-66 27275219-9 2015 In groups (2&3) positive significant correlation was recorded between (SBP) & (DBP) and total daily intake of total calories, carbohydrate, total fat, saturated fatty acids and cholesterol, and negative significant correlation with total daily intake of total protein, animal and vegetable protein, linolenic and linoleic fatty acids, while oleic fatty acid showed negative correlation with SBP&DBP in all groups. Adenosine Monophosphate 11-16 selenium binding protein 1 Homo sapiens 75-78 27275219-9 2015 In groups (2&3) positive significant correlation was recorded between (SBP) & (DBP) and total daily intake of total calories, carbohydrate, total fat, saturated fatty acids and cholesterol, and negative significant correlation with total daily intake of total protein, animal and vegetable protein, linolenic and linoleic fatty acids, while oleic fatty acid showed negative correlation with SBP&DBP in all groups. Adenosine Monophosphate 11-16 selenium binding protein 1 Homo sapiens 399-402 27275219-9 2015 In groups (2&3) positive significant correlation was recorded between (SBP) & (DBP) and total daily intake of total calories, carbohydrate, total fat, saturated fatty acids and cholesterol, and negative significant correlation with total daily intake of total protein, animal and vegetable protein, linolenic and linoleic fatty acids, while oleic fatty acid showed negative correlation with SBP&DBP in all groups. Adenosine Monophosphate 13-16 selenium binding protein 1 Homo sapiens 75-78 27275219-9 2015 In groups (2&3) positive significant correlation was recorded between (SBP) & (DBP) and total daily intake of total calories, carbohydrate, total fat, saturated fatty acids and cholesterol, and negative significant correlation with total daily intake of total protein, animal and vegetable protein, linolenic and linoleic fatty acids, while oleic fatty acid showed negative correlation with SBP&DBP in all groups. Carbohydrates 134-146 selenium binding protein 1 Homo sapiens 75-78 27275219-9 2015 In groups (2&3) positive significant correlation was recorded between (SBP) & (DBP) and total daily intake of total calories, carbohydrate, total fat, saturated fatty acids and cholesterol, and negative significant correlation with total daily intake of total protein, animal and vegetable protein, linolenic and linoleic fatty acids, while oleic fatty acid showed negative correlation with SBP&DBP in all groups. Fatty Acids 159-180 selenium binding protein 1 Homo sapiens 75-78 27275219-9 2015 In groups (2&3) positive significant correlation was recorded between (SBP) & (DBP) and total daily intake of total calories, carbohydrate, total fat, saturated fatty acids and cholesterol, and negative significant correlation with total daily intake of total protein, animal and vegetable protein, linolenic and linoleic fatty acids, while oleic fatty acid showed negative correlation with SBP&DBP in all groups. Cholesterol 185-196 selenium binding protein 1 Homo sapiens 75-78 27275219-9 2015 In groups (2&3) positive significant correlation was recorded between (SBP) & (DBP) and total daily intake of total calories, carbohydrate, total fat, saturated fatty acids and cholesterol, and negative significant correlation with total daily intake of total protein, animal and vegetable protein, linolenic and linoleic fatty acids, while oleic fatty acid showed negative correlation with SBP&DBP in all groups. linolenic 307-316 selenium binding protein 1 Homo sapiens 75-78 27275219-9 2015 In groups (2&3) positive significant correlation was recorded between (SBP) & (DBP) and total daily intake of total calories, carbohydrate, total fat, saturated fatty acids and cholesterol, and negative significant correlation with total daily intake of total protein, animal and vegetable protein, linolenic and linoleic fatty acids, while oleic fatty acid showed negative correlation with SBP&DBP in all groups. Linoleic Acid 321-341 selenium binding protein 1 Homo sapiens 75-78 27275219-9 2015 In groups (2&3) positive significant correlation was recorded between (SBP) & (DBP) and total daily intake of total calories, carbohydrate, total fat, saturated fatty acids and cholesterol, and negative significant correlation with total daily intake of total protein, animal and vegetable protein, linolenic and linoleic fatty acids, while oleic fatty acid showed negative correlation with SBP&DBP in all groups. oleic fatty acid 324-340 selenium binding protein 1 Homo sapiens 75-78 27275219-9 2015 In groups (2&3) positive significant correlation was recorded between (SBP) & (DBP) and total daily intake of total calories, carbohydrate, total fat, saturated fatty acids and cholesterol, and negative significant correlation with total daily intake of total protein, animal and vegetable protein, linolenic and linoleic fatty acids, while oleic fatty acid showed negative correlation with SBP&DBP in all groups. Adenosine Monophosphate 81-84 selenium binding protein 1 Homo sapiens 75-78 25319120-4 2015 RESULTS: We observed a significant decrease of SBP and DBP in the canrenone group compared to baseline. Canrenone 66-75 selenium binding protein 1 Homo sapiens 47-50 25380148-9 2015 Amongst hypertensive women, SBP was within 5 mmHg of mercury BP in 94% of readings with the auscultatory device and 75% with the automated device (P = 0.021); DBP was within 5 mmHg in 97 and 61% readings, respectively (P = 0.001). Mercury 53-60 selenium binding protein 1 Homo sapiens 28-31 25479026-8 2015 Male P-MBG responders vs. nonresponders (above vs. below median of high-salt induced P-MBG increase) had markedly enhanced SBP (10.4 +- 6.4 vs. 1.0 +- 6.0 mmHg; P = 0.003) and DBP (6.7 +- 5.0 vs. -0.6 +- 3.6 mmHg; P = 0.001) salt sensitivity. Salts 72-76 selenium binding protein 1 Homo sapiens 123-126 25308878-4 2015 RESULTS: Four weeks of bilateral-leg IET resulted in a reduction in resting SBP (120 +- 12-115 +- 12 mmHg, p = 0.01). 1-(4-CYANO-PHENYL)-3-[2-(2,6-DICHLORO-PHENYL)-1-IMINO-ETHYL]-THIOUREA 37-40 selenium binding protein 1 Homo sapiens 76-79 25445402-0 2015 Reduction of selenium-binding protein 1 sensitizes cancer cells to selenite via elevating extracellular glutathione: a novel mechanism of cancer-specific cytotoxicity of selenite. Glutathione 104-115 selenium binding protein 1 Homo sapiens 13-39 25445402-0 2015 Reduction of selenium-binding protein 1 sensitizes cancer cells to selenite via elevating extracellular glutathione: a novel mechanism of cancer-specific cytotoxicity of selenite. Selenious Acid 67-75 selenium binding protein 1 Homo sapiens 13-39 25445402-3 2015 This study was to investigate the roles of two distinct representatives of selenium-containing proteins, selenium-binding protein 1 (SBP1) and glutathione peroxidase 1 (GPX1), in selenite-mediated cancer-specific cytotoxicity. Selenium 75-83 selenium binding protein 1 Homo sapiens 105-131 25445402-3 2015 This study was to investigate the roles of two distinct representatives of selenium-containing proteins, selenium-binding protein 1 (SBP1) and glutathione peroxidase 1 (GPX1), in selenite-mediated cancer-specific cytotoxicity. Selenium 75-83 selenium binding protein 1 Homo sapiens 133-137 25445402-3 2015 This study was to investigate the roles of two distinct representatives of selenium-containing proteins, selenium-binding protein 1 (SBP1) and glutathione peroxidase 1 (GPX1), in selenite-mediated cancer-specific cytotoxicity. Selenious Acid 179-187 selenium binding protein 1 Homo sapiens 105-131 25445402-3 2015 This study was to investigate the roles of two distinct representatives of selenium-containing proteins, selenium-binding protein 1 (SBP1) and glutathione peroxidase 1 (GPX1), in selenite-mediated cancer-specific cytotoxicity. Selenious Acid 179-187 selenium binding protein 1 Homo sapiens 133-137 25445402-6 2015 Reduction of SBP1 in cancer cells and epirubicin-resistant cells on selenite exposure resulted in a dramatic increase in the generation of hydrogen peroxide and superoxide anion, which in turn caused oxidative stress and triggered apoptosis. Hydrogen Peroxide 139-156 selenium binding protein 1 Homo sapiens 13-17 25445402-6 2015 Reduction of SBP1 in cancer cells and epirubicin-resistant cells on selenite exposure resulted in a dramatic increase in the generation of hydrogen peroxide and superoxide anion, which in turn caused oxidative stress and triggered apoptosis. Superoxides 161-177 selenium binding protein 1 Homo sapiens 13-17 25445402-7 2015 Furthermore, knockdown SBP1 by small interfering RNA increased selenite sensitivity by elevating extracellular glutathione (GSH), which spontaneously reacted with selenite and led to the rapid depletion of selenium (IV) in growth medium and the high-affinity uptake of selenite. Selenious Acid 63-71 selenium binding protein 1 Homo sapiens 23-27 25445402-7 2015 Furthermore, knockdown SBP1 by small interfering RNA increased selenite sensitivity by elevating extracellular glutathione (GSH), which spontaneously reacted with selenite and led to the rapid depletion of selenium (IV) in growth medium and the high-affinity uptake of selenite. Glutathione 111-122 selenium binding protein 1 Homo sapiens 23-27 25445402-7 2015 Furthermore, knockdown SBP1 by small interfering RNA increased selenite sensitivity by elevating extracellular glutathione (GSH), which spontaneously reacted with selenite and led to the rapid depletion of selenium (IV) in growth medium and the high-affinity uptake of selenite. Glutathione 124-127 selenium binding protein 1 Homo sapiens 23-27 25445402-7 2015 Furthermore, knockdown SBP1 by small interfering RNA increased selenite sensitivity by elevating extracellular glutathione (GSH), which spontaneously reacted with selenite and led to the rapid depletion of selenium (IV) in growth medium and the high-affinity uptake of selenite. Selenious Acid 163-171 selenium binding protein 1 Homo sapiens 23-27 25445402-7 2015 Furthermore, knockdown SBP1 by small interfering RNA increased selenite sensitivity by elevating extracellular glutathione (GSH), which spontaneously reacted with selenite and led to the rapid depletion of selenium (IV) in growth medium and the high-affinity uptake of selenite. Selenium 206-214 selenium binding protein 1 Homo sapiens 23-27 25445402-7 2015 Furthermore, knockdown SBP1 by small interfering RNA increased selenite sensitivity by elevating extracellular glutathione (GSH), which spontaneously reacted with selenite and led to the rapid depletion of selenium (IV) in growth medium and the high-affinity uptake of selenite. Selenious Acid 163-171 selenium binding protein 1 Homo sapiens 23-27 25445402-8 2015 In conclusion, these findings would improve our understanding of the roles of selenium-containing proteins in selenite-mediated cytotoxicity, and revealed a potent mechanism of the selective cytotoxicity of selenite in cancer cells and drug-resistant cells, in which SBP1 was likely to play an important role in modulating the extracellular microenvironment by regulating the levels of extracellular GSH. Glutathione 400-403 selenium binding protein 1 Homo sapiens 267-271 25983770-8 2015 Results showed a significant increase in systolic and diastolic blood pressure (SBP and DBP) in anabolic steroid users which associates with duration of abuse (P = 0.02 and P = 0.03, respectively). Steroids 105-112 selenium binding protein 1 Homo sapiens 80-83 25479028-6 2015 Green tea or GTE produced a significant effect on both SBP (mean difference -1.42 mmHg, 95% confidence interval -2.47 to -0.36, P = 0.008; I = 52%, P = 0.01 for heterogeneity) and DBP (mean difference -1.25 mmHg, 95% confidence interval -2.32 to -0.19, P = 0.02; I = 74%, P < 0.001 for heterogeneity), compared with placebo. gte 13-16 selenium binding protein 1 Homo sapiens 55-58 25485720-11 2015 In RCTs comparing calcium antagonists, angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) with placebo smaller SBP/DBP differences were achieved, mostly because in the majority of these later RCTs the antihypertensive drug and placebo were added on a background treatment with other antihypertensive agents. Calcium 18-25 selenium binding protein 1 Homo sapiens 148-151 25613811-1 2015 BACKGROUND: To compare the effect of bimatoprost and the fixed combination latanoprost-timolol (LTFC) on 24-hour systolic (SBP) and diastolic (DBP) blood pressure and on 24-hour ocular perfusion pressure (OPP). Bimatoprost 37-48 selenium binding protein 1 Homo sapiens 123-126 25540822-6 2015 Together, our approaches identified 40 new SBP ligands, generated experiment-based annotations for 2084 SBPs in 71 isofunctional clusters, and defined numerous metabolic pathways, including novel catabolic pathways for the utilization of ethanolamine as sole nitrogen source and the use of d-Ala-d-Ala as sole carbon source. Ethanolamine 238-250 selenium binding protein 1 Homo sapiens 43-46 25540822-6 2015 Together, our approaches identified 40 new SBP ligands, generated experiment-based annotations for 2084 SBPs in 71 isofunctional clusters, and defined numerous metabolic pathways, including novel catabolic pathways for the utilization of ethanolamine as sole nitrogen source and the use of d-Ala-d-Ala as sole carbon source. Nitrogen 259-267 selenium binding protein 1 Homo sapiens 43-46 25540822-6 2015 Together, our approaches identified 40 new SBP ligands, generated experiment-based annotations for 2084 SBPs in 71 isofunctional clusters, and defined numerous metabolic pathways, including novel catabolic pathways for the utilization of ethanolamine as sole nitrogen source and the use of d-Ala-d-Ala as sole carbon source. alanylalanine 290-301 selenium binding protein 1 Homo sapiens 43-46 25540822-6 2015 Together, our approaches identified 40 new SBP ligands, generated experiment-based annotations for 2084 SBPs in 71 isofunctional clusters, and defined numerous metabolic pathways, including novel catabolic pathways for the utilization of ethanolamine as sole nitrogen source and the use of d-Ala-d-Ala as sole carbon source. Carbon 310-316 selenium binding protein 1 Homo sapiens 43-46 28294808-6 2015 Administration of lercanidipine/enalapril combination was associated with mean 24-hour SBP and DBP lowering (by15.3 and 8.7%, respectively). lercanidipine 18-31 selenium binding protein 1 Homo sapiens 87-90 28294808-6 2015 Administration of lercanidipine/enalapril combination was associated with mean 24-hour SBP and DBP lowering (by15.3 and 8.7%, respectively). Enalapril 32-41 selenium binding protein 1 Homo sapiens 87-90 25613811-1 2015 BACKGROUND: To compare the effect of bimatoprost and the fixed combination latanoprost-timolol (LTFC) on 24-hour systolic (SBP) and diastolic (DBP) blood pressure and on 24-hour ocular perfusion pressure (OPP). Xalacom 75-94 selenium binding protein 1 Homo sapiens 123-126 25613811-1 2015 BACKGROUND: To compare the effect of bimatoprost and the fixed combination latanoprost-timolol (LTFC) on 24-hour systolic (SBP) and diastolic (DBP) blood pressure and on 24-hour ocular perfusion pressure (OPP). ltfc 96-100 selenium binding protein 1 Homo sapiens 123-126 25613811-8 2015 Holter SBP was significantly higher for bimatoprost (135.1 mmHg vs 128.1 mmHg, p=0.04), while no statistically significant difference in DBP was found. Bimatoprost 40-51 selenium binding protein 1 Homo sapiens 7-10 25816110-7 2015 The rates of achievement of SBP < 135 mmHg both in the morning and evening were: 81.8% and 21.4% in Los/HCTZ- and High-Los-treated isolated morning hypertension (p = 0.003), respectively; and 61.4% and 36.6% in Los/HCTX- and High-Los-treated sustained hypertension (p = 0.022), respectively. Hydrochlorothiazide 107-111 selenium binding protein 1 Homo sapiens 28-31 25377916-7 2015 In T1D, PUA levels correlated positively with SBP (P = 0.029) and negatively with ERPF (P = 0.031) and GFR (P = 0.028). U-PI-A-PI 8-11 selenium binding protein 1 Homo sapiens 46-49 24490621-10 2015 Correlations were observed between changes in SBP and changes in NO, CO and H2S (r = -0.45, -0.51 and -0.46, respectively, all p < 0.05), and between changes in MAP and changes in NO, CO and H2S (r = -0.36, -0.45 and -0.42, respectively, all p < 0.05). Carbon Monoxide 69-71 selenium binding protein 1 Homo sapiens 46-49 24490621-10 2015 Correlations were observed between changes in SBP and changes in NO, CO and H2S (r = -0.45, -0.51 and -0.46, respectively, all p < 0.05), and between changes in MAP and changes in NO, CO and H2S (r = -0.36, -0.45 and -0.42, respectively, all p < 0.05). Hydrogen Sulfide 76-79 selenium binding protein 1 Homo sapiens 46-49 24490621-10 2015 Correlations were observed between changes in SBP and changes in NO, CO and H2S (r = -0.45, -0.51 and -0.46, respectively, all p < 0.05), and between changes in MAP and changes in NO, CO and H2S (r = -0.36, -0.45 and -0.42, respectively, all p < 0.05). Carbon Monoxide 187-189 selenium binding protein 1 Homo sapiens 46-49 24490621-10 2015 Correlations were observed between changes in SBP and changes in NO, CO and H2S (r = -0.45, -0.51 and -0.46, respectively, all p < 0.05), and between changes in MAP and changes in NO, CO and H2S (r = -0.36, -0.45 and -0.42, respectively, all p < 0.05). Hydrogen Sulfide 194-197 selenium binding protein 1 Homo sapiens 46-49 26114353-7 2015 SBP at T2 was associated with increasing age (R = 0.44), serum creatinine (R = 0.32), SUA (R = 0.30), mean preoperative SBP and DBP (R = 0.54 and 0.37, respectively), and reduced estimated glomerular filtration rate (eGFR) (R = -0.44). Creatinine 63-73 selenium binding protein 1 Homo sapiens 0-3 26114353-7 2015 SBP at T2 was associated with increasing age (R = 0.44), serum creatinine (R = 0.32), SUA (R = 0.30), mean preoperative SBP and DBP (R = 0.54 and 0.37, respectively), and reduced estimated glomerular filtration rate (eGFR) (R = -0.44). sua 86-89 selenium binding protein 1 Homo sapiens 0-3 25919438-11 2015 Multiple linear regression showed that the SBP increased 0.017 mmHg with the increasing of 1 mumol/L deviation of SUA in group P. CONCLUSIONS: SUA levels predict SBP elevation and hypertension incidence in population with pre-hypertension, however, do not predict the DBP elevation in pre-hypertensive population as well as change of BP in ideal blood pressure population. sua 114-117 selenium binding protein 1 Homo sapiens 43-46 25919438-11 2015 Multiple linear regression showed that the SBP increased 0.017 mmHg with the increasing of 1 mumol/L deviation of SUA in group P. CONCLUSIONS: SUA levels predict SBP elevation and hypertension incidence in population with pre-hypertension, however, do not predict the DBP elevation in pre-hypertensive population as well as change of BP in ideal blood pressure population. sua 143-146 selenium binding protein 1 Homo sapiens 43-46 25919438-11 2015 Multiple linear regression showed that the SBP increased 0.017 mmHg with the increasing of 1 mumol/L deviation of SUA in group P. CONCLUSIONS: SUA levels predict SBP elevation and hypertension incidence in population with pre-hypertension, however, do not predict the DBP elevation in pre-hypertensive population as well as change of BP in ideal blood pressure population. sua 143-146 selenium binding protein 1 Homo sapiens 162-165 26164986-6 2015 Administration of lercanidipine/enalapril combination was associated with mean 24-hour SBP and DBP lowering (by15.3 and 8.7%, respectively). lercanidipine 18-31 selenium binding protein 1 Homo sapiens 87-90 25784950-9 2015 For the risk factors of stroke, pooled analysis demonstrated that TCC exercise was associated with lower body weight, BMI, FBG level, and decreasing SBP, DBP, plasma TC, and LDL-C level regardless of the intervention period less than half a year or more than one year and significantly raised HDL-C level in comparison to nonintervention. Technetium 66-68 selenium binding protein 1 Homo sapiens 149-152 25966297-9 2015 PPCM patients with low SBP and high HR were less likely to be on ACE-inhibitors (n = 35, 69% versus n = 129, 84%, p = 0.024) and on the beta blocker carvedilol (n = 24, 47% versus n = 98, 64%, p = 0.047). Carvedilol 149-159 selenium binding protein 1 Homo sapiens 23-26 26164986-6 2015 Administration of lercanidipine/enalapril combination was associated with mean 24-hour SBP and DBP lowering (by15.3 and 8.7%, respectively). Enalapril 32-41 selenium binding protein 1 Homo sapiens 87-90 26447525-2 2015 Conversely, SBP is influenced by IBI via non-baroreflex mechanisms. BI 6727 33-36 selenium binding protein 1 Homo sapiens 12-15 25469985-8 2014 The meta-analyses of MS and obesity markers indicated that TG, TC, CRP BMI, TBF%, WC, WHR and Leptin were positively correlated with chemerin, nevertheless, SBP, DBP, LDL-C, HDL-C, ALT and r-GT were not significantly correlated, adiponectin was negatively correlated. Thioguanine 59-61 selenium binding protein 1 Homo sapiens 157-160 25499383-4 2014 Randomized studies comparing eplerenone with placebo or other antihypertensive drugs for net reduction of systolic and diastolic blood pressures (SBP; DBP) from baseline and for incidence of adverse events were considered. Eplerenone 29-39 selenium binding protein 1 Homo sapiens 146-149 25401978-4 2014 RESULTS: In multiple linear regression analysis, baseline tHcy levels associated with age, BMI, SBP, DBP, LDL-C and Cr independently over 4.8-years follow-up; age, BMI, SBP, DBP and Cr were found to be associated with tHcy levels independently at the end of follow-up. thcy 58-62 selenium binding protein 1 Homo sapiens 96-99 25401978-4 2014 RESULTS: In multiple linear regression analysis, baseline tHcy levels associated with age, BMI, SBP, DBP, LDL-C and Cr independently over 4.8-years follow-up; age, BMI, SBP, DBP and Cr were found to be associated with tHcy levels independently at the end of follow-up. thcy 58-62 selenium binding protein 1 Homo sapiens 169-172 25499383-8 2014 In the overall comparison, reduction of both SBP and DBP with eplerenone was greater than other antihypertensive agents (WMD for SBP -1.50 mm Hg, p < 0.0001; WMD for DBP -0.54 mm Hg, p < 0.00001); this was essentially driven by a greater anti-hypertensive action vs enalapril and losartan for SBP and vs losartan for DBP. Eplerenone 62-72 selenium binding protein 1 Homo sapiens 129-132 25499383-7 2014 Compared to placebo, eplerenone significantly reduced either SBP [WMD -8.07, 95% CI -8.17 to -7.96 mm Hg, p < 0.00001] and DBP [WMD -4.08, -4.15 to -4.01 mm Hg, p < 0.00001]. Eplerenone 21-31 selenium binding protein 1 Homo sapiens 61-64 25441531-7 2014 The mean decrease in SBP during transport was 51 mm Hg in the IBP group versus 34 mm Hg in the NIBP group (P < .001). ibp 62-65 selenium binding protein 1 Homo sapiens 21-24 25441531-9 2014 The IBP group met the SBP goal more frequently than the NIBP group (P < .05) when the SBP was noted as greater than 140 mm Hg during transport. ibp 4-7 selenium binding protein 1 Homo sapiens 22-25 25441531-9 2014 The IBP group met the SBP goal more frequently than the NIBP group (P < .05) when the SBP was noted as greater than 140 mm Hg during transport. ibp 4-7 selenium binding protein 1 Homo sapiens 89-92 25338053-8 2014 Furthermore, the whole distribution of blood pressure showed an overall decline in SBP/DBP and the proportion of patients with BP under control (SBP/DBP<140 mmHg) was significantly higher in salt-substitute group in comparison to the regular salt group (19.2% vs. 8.8%, p = 0.027). Salts 194-198 selenium binding protein 1 Homo sapiens 83-86 25096646-8 2014 Single and partial regression analyses indicated a negative association between urinary 8-oxodG levels with SBP, DBP and PP only in African men. 8-ohdg 88-95 selenium binding protein 1 Homo sapiens 108-111 26060717-4 2014 RESULTS: On univariate analysis, SUA was positively correlated with age, SBP, DBP, BMI, FPG, red blood cell count, hemoglobin, white blood cell count, platelet, cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol, ALT, AST, bilirubin, albumin, BUN and creatinine. sua 33-36 selenium binding protein 1 Homo sapiens 73-76 25550864-18 2014 The serum creatine level was related to patient gender (P = 0.0077), SBP (P < 0.0001), DBP (0.0049), IgG (P-0.0006), and C3 (P = 0.0113). Creatine 10-18 selenium binding protein 1 Homo sapiens 69-72 25338053-8 2014 Furthermore, the whole distribution of blood pressure showed an overall decline in SBP/DBP and the proportion of patients with BP under control (SBP/DBP<140 mmHg) was significantly higher in salt-substitute group in comparison to the regular salt group (19.2% vs. 8.8%, p = 0.027). Salts 194-198 selenium binding protein 1 Homo sapiens 145-148 24957042-8 2014 Hoechst 33258/propidium iodide dual staining and flow cytometric analysis showed that SBP induced MDA-MB-231 cell apoptosis. Bisbenzimidazole 0-13 selenium binding protein 1 Homo sapiens 86-89 24661019-7 2014 In the NT group, systolic (SBP) or diastolic (DBP) BP significantly increased (all P < 0 005) when acromegaly was uncontrolled, but did not change when the disease was controlled. nt 7-9 selenium binding protein 1 Homo sapiens 27-30 25050539-8 2014 Among these, collapsin response mediator protein 2 (CRMP-2), DNA replication complex GINS protein PSF2 (PSF-2) and selenium-binding protein 1 (SBP-1) were notable not only for their differential expression but also for decreased expression following 5-FU exposure, indicating their possible roles as novel biomarkers for sensitivity (CRMP-2, PSF-2) as well as resistance (SBP-1) to 5-FU. Fluorouracil 250-254 selenium binding protein 1 Homo sapiens 115-141 25050539-8 2014 Among these, collapsin response mediator protein 2 (CRMP-2), DNA replication complex GINS protein PSF2 (PSF-2) and selenium-binding protein 1 (SBP-1) were notable not only for their differential expression but also for decreased expression following 5-FU exposure, indicating their possible roles as novel biomarkers for sensitivity (CRMP-2, PSF-2) as well as resistance (SBP-1) to 5-FU. Fluorouracil 250-254 selenium binding protein 1 Homo sapiens 143-148 25050539-8 2014 Among these, collapsin response mediator protein 2 (CRMP-2), DNA replication complex GINS protein PSF2 (PSF-2) and selenium-binding protein 1 (SBP-1) were notable not only for their differential expression but also for decreased expression following 5-FU exposure, indicating their possible roles as novel biomarkers for sensitivity (CRMP-2, PSF-2) as well as resistance (SBP-1) to 5-FU. Fluorouracil 382-386 selenium binding protein 1 Homo sapiens 115-141 25050539-8 2014 Among these, collapsin response mediator protein 2 (CRMP-2), DNA replication complex GINS protein PSF2 (PSF-2) and selenium-binding protein 1 (SBP-1) were notable not only for their differential expression but also for decreased expression following 5-FU exposure, indicating their possible roles as novel biomarkers for sensitivity (CRMP-2, PSF-2) as well as resistance (SBP-1) to 5-FU. Fluorouracil 382-386 selenium binding protein 1 Homo sapiens 143-148 24955609-5 2014 RESULTS: Maternal pBMI was positively associated with offspring"s WHtR (beta = 0.025; 95% confidence interval [CI], 0.010-0.039), SBP (beta = 0.020; 95% CI, 0.005-0.0035), DBP (beta = 0.016; 95% CI, 0.000-0.031), and metabolic score (beta = 0.078; 95% CI, 0.039-0.118) after adjusting. pbmi 18-22 selenium binding protein 1 Homo sapiens 130-133 24955609-9 2014 An interaction between maternal pBMI and postnatal weight gain was present in the association with SBP (P = .021) and metabolic score (P = .047), and between maternal pBMI and postnatal weight-for-length gain in the association with triglycerides (P = .022) and metabolic score (P = .042). pbmi 32-36 selenium binding protein 1 Homo sapiens 99-102 24957042-8 2014 Hoechst 33258/propidium iodide dual staining and flow cytometric analysis showed that SBP induced MDA-MB-231 cell apoptosis. Propidium 14-30 selenium binding protein 1 Homo sapiens 86-89 24957042-10 2014 In addition, sodium palmitate could rescue the cell apoptosis induced by SBP. Palmitic Acid 13-29 selenium binding protein 1 Homo sapiens 73-76 25227434-1 2014 BACKGROUND: The anticancer effects of selenium may be mediated by selenium-binding proteins, such as SELENBP1. Selenium 38-46 selenium binding protein 1 Homo sapiens 101-109 24942766-5 2014 During Period II, each olmesartan/amlodipine combination reduced 24-h systolic and diastolic BP (SBP/DBP), as well as morning and early morning SBP/DBP, significantly more than amlodipine 5 mg (P<0.001 for all). olmesartan 23-33 selenium binding protein 1 Homo sapiens 97-100 24942766-5 2014 During Period II, each olmesartan/amlodipine combination reduced 24-h systolic and diastolic BP (SBP/DBP), as well as morning and early morning SBP/DBP, significantly more than amlodipine 5 mg (P<0.001 for all). olmesartan 23-33 selenium binding protein 1 Homo sapiens 144-147 24942766-6 2014 TPRs were higher in each olmesartan/amlodipine group than with amlodipine 5 mg, and SI values showed dose-related increases; olmesartan/amlodipine 40/5 mg produced a significantly higher SI for SBP and DBP (1.55 and 1.33, respectively) than amlodipine 5 mg (0.96 and 0.77, respectively, P<0.0001 for each). olmesartan 125-135 selenium binding protein 1 Homo sapiens 194-197 24942766-5 2014 During Period II, each olmesartan/amlodipine combination reduced 24-h systolic and diastolic BP (SBP/DBP), as well as morning and early morning SBP/DBP, significantly more than amlodipine 5 mg (P<0.001 for all). Amlodipine 34-44 selenium binding protein 1 Homo sapiens 97-100 24569413-10 2014 The age at which the importance of SBP exceeded DBP was for stroke mortality influenced by sex, cholesterol, and country risk. Cholesterol 96-107 selenium binding protein 1 Homo sapiens 35-38 25029492-5 2014 Linear regression estimated associations between PbB and SBP and DBP. Polybrominated Biphenyls 49-52 selenium binding protein 1 Homo sapiens 57-60 25029492-9 2014 In adjusted regression models, a modest association emerged between PbB levels and SBP among 40- to 54-year-olds, and between PbB levels and DBP for the overall population. Polybrominated Biphenyls 68-71 selenium binding protein 1 Homo sapiens 83-86 25341300-11 2014 Proportional relationships were found between BMI, WC, and SBP and high blood glucose. Glucose 78-85 selenium binding protein 1 Homo sapiens 59-62 25174466-8 2014 2)The means of baPWV for the above groups of SBP were 1 322.19, 1 456.27, 1 544.78 and 1 827.77 cm/s, respectively, with detection rates of baPWV >= 1 400 cm/s as 26.4% , 49.3% , 64.2% and 88.3% , respectively. bapwv 15-20 selenium binding protein 1 Homo sapiens 45-48 25174466-8 2014 2)The means of baPWV for the above groups of SBP were 1 322.19, 1 456.27, 1 544.78 and 1 827.77 cm/s, respectively, with detection rates of baPWV >= 1 400 cm/s as 26.4% , 49.3% , 64.2% and 88.3% , respectively. bapwv 140-145 selenium binding protein 1 Homo sapiens 45-48 25174466-10 2014 4) Data from the Multiple logistic regression analysis showed that after adjusting for age, gender and other risk factors, when compared to optimal SBP, factors as high-normal blood pressure I period, high-normal blood pressure II period and hypertension were risk factors for increasing baPWV, with OR values as 2.70 (95% CI:2.20-3.32), 4.56(95% CI: 3.67-5.67) and 13.51 (95% CI:10.87-16.78), respectively. bapwv 288-293 selenium binding protein 1 Homo sapiens 148-151 25174466-11 2014 CONCLUSION: Higher SBP seemed an independent risk factor for the increase of baPWV. bapwv 77-82 selenium binding protein 1 Homo sapiens 19-22 24805955-0 2014 A polymorphism in the major gene regulating serum uric acid associates with clinic SBP and the white-coat effect in a family-based study. Uric Acid 50-59 selenium binding protein 1 Homo sapiens 83-86 24399485-10 2014 A higher resting heart rate, a lower SBP at presentation, a higher initial intrapericardial pressure, and a lower cardiac index were the statistically significant predictors of a >15% increase in cardiac index. Aminoglutethimide 177-182 selenium binding protein 1 Homo sapiens 37-40 24798657-5 2014 Sleep SBP surge (difference between the hypoxia-peak SBP measured by oxygen-triggered function and SBPs within 30 minutes before and after the peak SBP) was only significantly reduced by carvedilol (P<.05). Oxygen 69-75 selenium binding protein 1 Homo sapiens 6-9 24798657-5 2014 Sleep SBP surge (difference between the hypoxia-peak SBP measured by oxygen-triggered function and SBPs within 30 minutes before and after the peak SBP) was only significantly reduced by carvedilol (P<.05). Oxygen 69-75 selenium binding protein 1 Homo sapiens 53-56 24798657-5 2014 Sleep SBP surge (difference between the hypoxia-peak SBP measured by oxygen-triggered function and SBPs within 30 minutes before and after the peak SBP) was only significantly reduced by carvedilol (P<.05). Oxygen 69-75 selenium binding protein 1 Homo sapiens 53-56 24798657-5 2014 Sleep SBP surge (difference between the hypoxia-peak SBP measured by oxygen-triggered function and SBPs within 30 minutes before and after the peak SBP) was only significantly reduced by carvedilol (P<.05). Carvedilol 187-197 selenium binding protein 1 Homo sapiens 6-9 24798657-5 2014 Sleep SBP surge (difference between the hypoxia-peak SBP measured by oxygen-triggered function and SBPs within 30 minutes before and after the peak SBP) was only significantly reduced by carvedilol (P<.05). Carvedilol 187-197 selenium binding protein 1 Homo sapiens 53-56 24798657-5 2014 Sleep SBP surge (difference between the hypoxia-peak SBP measured by oxygen-triggered function and SBPs within 30 minutes before and after the peak SBP) was only significantly reduced by carvedilol (P<.05). Carvedilol 187-197 selenium binding protein 1 Homo sapiens 53-56 24737289-6 2014 In the CRC cell lines, NaB treatment led to the upregulation of SELENBP1, CEA and AKP when compared with the untreated cells (2.24- to 4.82-fold). nab 23-26 selenium binding protein 1 Homo sapiens 64-72 24737289-7 2014 SELENBP1 was also upregulated in cells treated with TSA alone (1.25- to 3.64-fold), or in combination with 5-Aza-dC (1.32- to 4.13-fold). trichostatin A 52-55 selenium binding protein 1 Homo sapiens 0-8 24737289-7 2014 SELENBP1 was also upregulated in cells treated with TSA alone (1.25- to 3.64-fold), or in combination with 5-Aza-dC (1.32- to 4.13-fold). Decitabine 107-115 selenium binding protein 1 Homo sapiens 0-8 24311451-3 2014 RESULTS: Although body weight was reduced similarly in both groups, the BB group showed greater HbA1c and systolic blood pressure reductions (HbA1c: -4.62% vs. -1.46%, p = 0.047; SBP -9.58 vs. -2.43 mmHg; p = 0.04). boeravinone B 72-74 selenium binding protein 1 Homo sapiens 179-182 24418378-10 2014 TG, SBP, and DBP exhibited linear associations with 25(OH)D. CONCLUSIONS: Vitamin D status is related to cardiometabolic indicators in healthy men. Vitamin D 74-83 selenium binding protein 1 Homo sapiens 4-7 24949036-12 2014 With respect to metabolic parameters, the patients in the higher UA quartiles exhibited higher levels of body mass index (BMI), SBP, FBG and triglycerides (TG). Uric Acid 65-67 selenium binding protein 1 Homo sapiens 128-131 24531056-7 2014 RESULTS: A 10-mug/m3 increase in NO2 levels was associated with 1.34 mmHg (95% CI: 0.14, 2.55) higher SBP in nonmedicated individuals, after adjusting for transportation noise. Nitrogen Dioxide 33-36 selenium binding protein 1 Homo sapiens 102-105 24531056-11 2014 Associations of NO2 with SBP and DBP were stronger in participants with cardiovascular disease, and the association with SBP was stronger in those exposed to high traffic density and traffic noise levels >= 55 dB(A). Nitrogen Dioxide 16-19 selenium binding protein 1 Homo sapiens 25-28 24531056-12 2014 CONCLUSIONS: We observed a positive association between long-term exposure to NO2 and SBP, after adjustment for transportation noise, which was sensitive to the methodology used to account for medication. Nitrogen Dioxide 78-81 selenium binding protein 1 Homo sapiens 86-89 24529122-9 2014 In multivariate analysis, lower SBP-dip (P = 0.007) and DBP-dip (P = 0.03) were independently associated with lower GTN response. Nitroglycerin 116-119 selenium binding protein 1 Homo sapiens 32-35 24007334-8 2014 After reaching the primary end point and during the clevidipine infusion, 17.5% and 11.8% of SBP readings were above the upper and below the lower goals, respectively. clevidipine 52-63 selenium binding protein 1 Homo sapiens 93-96 24007334-11 2014 CONCLUSION: Clevidipine controlled SBP in all patients with aneurysmal SAH in <22 min and kept it within the elective range 70% of the time without major complications. clevidipine 12-23 selenium binding protein 1 Homo sapiens 35-38 24562633-10 2014 Patients with lower knowledge scores (B = -0.01, P &lt; 0.001) and those who were advised to cut down on salt (B = 0.02, P = 0.037) had higher SBP levels when controlled for gender, race, and awareness of their blood pressure goals. Adenosine Monophosphate 52-55 selenium binding protein 1 Homo sapiens 147-150 24562633-10 2014 Patients with lower knowledge scores (B = -0.01, P &lt; 0.001) and those who were advised to cut down on salt (B = 0.02, P = 0.037) had higher SBP levels when controlled for gender, race, and awareness of their blood pressure goals. Salts 109-113 selenium binding protein 1 Homo sapiens 147-150 24629401-7 2014 The supine SBP of the sOHT group were similar to that of sONT group (140.9 +- 20.2 mm Hg vs 138.2 +- 19.7 mm Hg), but significantly lower than that of sOH group (151.9 +- 19.2 mm Hg; P < .05). soht 22-26 selenium binding protein 1 Homo sapiens 11-14 24629401-7 2014 The supine SBP of the sOHT group were similar to that of sONT group (140.9 +- 20.2 mm Hg vs 138.2 +- 19.7 mm Hg), but significantly lower than that of sOH group (151.9 +- 19.2 mm Hg; P < .05). SOH 22-25 selenium binding protein 1 Homo sapiens 11-14 24998653-6 2014 RESULTS: After treatment by atorvastatin, the resting SBP, pulse pressure, the peak exercise SBP and BNP were significantly decreased; and the exercise time, metabolic equivalent, maximal oxygen uptake and anaerobic threshold were increased. Atorvastatin 28-40 selenium binding protein 1 Homo sapiens 54-57 24998653-6 2014 RESULTS: After treatment by atorvastatin, the resting SBP, pulse pressure, the peak exercise SBP and BNP were significantly decreased; and the exercise time, metabolic equivalent, maximal oxygen uptake and anaerobic threshold were increased. Atorvastatin 28-40 selenium binding protein 1 Homo sapiens 93-96 24998653-10 2014 CONCLUSION: In patients with diastolic dysfunction at rest and exercise-induced hypertension, atorvastatin can effectively reduce plasma hs-CRP and ET level, lower blood pressure and peak exercise SBP, decrease peak exercise plasma BNP concentration, and ultimately improve exercise tolerance. Atorvastatin 94-106 selenium binding protein 1 Homo sapiens 197-200 24602971-9 2014 Only canagliflozin had a significant dose-response relationship with SBP (P = .008). Canagliflozin 5-18 selenium binding protein 1 Homo sapiens 69-72 24447746-10 2014 CONCLUSIONS: This study revealed that appropriate PAC use effectively decreases in-hospital mortality in AHFS patients, particularly those with lower SBP or receiving inotropic therapy, suggesting that real-world PAC use could improve AHFS management. pac 50-53 selenium binding protein 1 Homo sapiens 150-153 24447746-10 2014 CONCLUSIONS: This study revealed that appropriate PAC use effectively decreases in-hospital mortality in AHFS patients, particularly those with lower SBP or receiving inotropic therapy, suggesting that real-world PAC use could improve AHFS management. pac 213-216 selenium binding protein 1 Homo sapiens 150-153 27128224-2 2014 In Period 1, the sensitivity of each subject to orally administered tyramine was established by determining the dose of tyramine that elevates SBP >=30 mmHg on >=3 consecutive occasions (i.e., TYR303 ). Tyramine 68-76 selenium binding protein 1 Homo sapiens 143-146 24831619-12 2014 Influence of FPG and TC on SBP varied among streets/townships while relation between TC and DBP also varied. Technetium 21-23 selenium binding protein 1 Homo sapiens 27-30 24533060-8 2014 O-DMA producers had lower body fat% (p = 0.032), SBP (p = 0.02), total cholesterol (p = 0.002) than non-producers. o-dma 0-5 selenium binding protein 1 Homo sapiens 49-52 27128224-2 2014 In Period 1, the sensitivity of each subject to orally administered tyramine was established by determining the dose of tyramine that elevates SBP >=30 mmHg on >=3 consecutive occasions (i.e., TYR303 ). Tyramine 120-128 selenium binding protein 1 Homo sapiens 143-146 24395536-6 2014 The relationship between SBP1 and GPx-1 represents a unique example of a molecular interaction between selenium containing proteins with a likely significant impact on human health and disease. Selenium 103-111 selenium binding protein 1 Homo sapiens 25-29 26464857-12 2014 The maximum mean (SD) drop in blood pressure was seen by intravenous sodium nitroprusside; 80 (51) mm Hg in SBP. Nitroprusside 69-89 selenium binding protein 1 Homo sapiens 108-111 24346096-1 2014 INTRODUCTION: nab-Paclitaxel (nab-P) is approved, in the United States, in combination with carboplatin for the first-line treatment of advanced non-small-cell lung cancer, based on a randomized phase 3 trial of nab-P plus carboplatin (nab-P/C) versus solvent-based paclitaxel plus carboplatin (sb-P/C). nab 14-17 selenium binding protein 1 Homo sapiens 295-301 24346096-1 2014 INTRODUCTION: nab-Paclitaxel (nab-P) is approved, in the United States, in combination with carboplatin for the first-line treatment of advanced non-small-cell lung cancer, based on a randomized phase 3 trial of nab-P plus carboplatin (nab-P/C) versus solvent-based paclitaxel plus carboplatin (sb-P/C). Paclitaxel 18-28 selenium binding protein 1 Homo sapiens 295-301 24346096-1 2014 INTRODUCTION: nab-Paclitaxel (nab-P) is approved, in the United States, in combination with carboplatin for the first-line treatment of advanced non-small-cell lung cancer, based on a randomized phase 3 trial of nab-P plus carboplatin (nab-P/C) versus solvent-based paclitaxel plus carboplatin (sb-P/C). nab 30-33 selenium binding protein 1 Homo sapiens 295-301 25464684-11 2014 After four weeks yoga camp there was statistically significant lowering of pulse rate (77.58 +- 3.86 bpm), SBP (117.92 +- 6.76 mm Hg), DBP (78.68 +- 6.62 mm Hg). Cyclic AMP 22-26 selenium binding protein 1 Homo sapiens 107-110 25178076-6 2014 Administration of combination atorvastatin with standard treatment of CKD allowed to achieve significant reduction of levels of atherogenic lipid fractions, HbA1c, and uricemia, additional reductions in SBP and PBP by 4-5 mm Hg. Atorvastatin 30-42 selenium binding protein 1 Homo sapiens 203-206 24376456-7 2013 The effect of SNP rs10826334 (near SLC16A9) on SBP was significantly modulated by both the number of alcoholic drinks and the ounces of alcohol consumed per week (p-values of 1.27E-08 and 3.92E-08, respectively). Alcohols 101-108 selenium binding protein 1 Homo sapiens 47-50 25796860-4 2014 The study demonstrated the effectiveness of a fixed-dose combination of bisoprolol and amlodipine in patients with hypertension represented by the decrease of average SBP, DBP, heart rate, increase in the number of patients with a normal daily profile ("dipper"), decrease in the time index. Bisoprolol 72-82 selenium binding protein 1 Homo sapiens 167-170 25796860-4 2014 The study demonstrated the effectiveness of a fixed-dose combination of bisoprolol and amlodipine in patients with hypertension represented by the decrease of average SBP, DBP, heart rate, increase in the number of patients with a normal daily profile ("dipper"), decrease in the time index. Amlodipine 87-97 selenium binding protein 1 Homo sapiens 167-170 24346096-11 2014 CONCLUSION: In this trial of patients receiving first-line treatment for advanced non-small-cell lung cancer, nab-P/C was associated with statistically and clinically significant reductions in patient-reported neuropathy, neuropathic pain in the hands and feet, and hearing loss compared with sb-P/C. nab 110-113 selenium binding protein 1 Homo sapiens 293-299 24950113-5 2014 In caffeine and placebo conditions significant decreases (p < 0.05) were noted in SBP, MAP, and PVR between the pre- and post-exercise time points. Caffeine 3-11 selenium binding protein 1 Homo sapiens 85-88 24950113-6 2014 Notwithstanding, the mean values for SBP, DBP and MAP during the 9 h of post-exercise monitoring were increased (p < 0.05) for the caffeine. Caffeine 134-142 selenium binding protein 1 Homo sapiens 37-40 24126178-9 2013 Patients who entered the trial with a SBP >= 140 mm Hg at baseline obtained a significant reduction of 15 mm Hg in SBP and 7 mm Hg in DBP from flaxseed ingestion. Diosmin 137-140 selenium binding protein 1 Homo sapiens 38-41 24163737-2 2013 Selenium-binding protein 1 (SBP1) is a member of an unusual class of selenium-containing proteins that may function as a tumor suppressor in multiple cancer types and whose levels have been shown to be lower in cancers as compared to corresponding normal tissues. Selenium 69-77 selenium binding protein 1 Homo sapiens 0-26 24163737-2 2013 Selenium-binding protein 1 (SBP1) is a member of an unusual class of selenium-containing proteins that may function as a tumor suppressor in multiple cancer types and whose levels have been shown to be lower in cancers as compared to corresponding normal tissues. Selenium 69-77 selenium binding protein 1 Homo sapiens 28-32 24126178-11 2013 Circulating alpha-linolenic acid levels correlated with SBP and DBP, and lignan levels correlated with changes in DBP. alpha-Linolenic Acid 12-32 selenium binding protein 1 Homo sapiens 56-59 24061855-3 2013 Based on the recent crystal structure of D3R, we demonstrated that the 4-phenylpiperazine moiety in this class of D3R-selective compounds binds to the conserved orthosteric binding site, whereas the extended aryl amide moiety is oriented toward a divergent secondary binding pocket (SBP). 1-PHENYLPIPERAZINE 71-89 selenium binding protein 1 Homo sapiens 283-286 24338457-8 2013 However the statistical comparison between PP and TN revealed that the first group had a significant elevation of SBP and DBP Daily Mean Level (DML(SBP/DBP): 121 +- 2/81 +- 2 vs 112 +- 2/70 +- 2 mmHg, respectively, p = 0.007 and p = 0.002), confirming the MP diagnosis. 2-(4-toluidino)-6-naphthalenesulfonic acid 50-52 selenium binding protein 1 Homo sapiens 114-117 24338457-8 2013 However the statistical comparison between PP and TN revealed that the first group had a significant elevation of SBP and DBP Daily Mean Level (DML(SBP/DBP): 121 +- 2/81 +- 2 vs 112 +- 2/70 +- 2 mmHg, respectively, p = 0.007 and p = 0.002), confirming the MP diagnosis. 2-(4-toluidino)-6-naphthalenesulfonic acid 50-52 selenium binding protein 1 Homo sapiens 148-151 24126713-8 2013 Nebivolol/HCTZ lowered central SBP by 15.8 +- 14.9 mmHg and DBP 10.5 +- 8.4 mmHg, and with metoprolol/HCTZ by 13.5 +- 12.3 mmHg for SBP and 9.5 +- 6.8 mmHg for DBP (all P < 0.001). Nebivolol 0-9 selenium binding protein 1 Homo sapiens 31-34 24126713-8 2013 Nebivolol/HCTZ lowered central SBP by 15.8 +- 14.9 mmHg and DBP 10.5 +- 8.4 mmHg, and with metoprolol/HCTZ by 13.5 +- 12.3 mmHg for SBP and 9.5 +- 6.8 mmHg for DBP (all P < 0.001). Nebivolol 0-9 selenium binding protein 1 Homo sapiens 132-135 24126713-8 2013 Nebivolol/HCTZ lowered central SBP by 15.8 +- 14.9 mmHg and DBP 10.5 +- 8.4 mmHg, and with metoprolol/HCTZ by 13.5 +- 12.3 mmHg for SBP and 9.5 +- 6.8 mmHg for DBP (all P < 0.001). Hydrochlorothiazide 10-14 selenium binding protein 1 Homo sapiens 31-34 24126713-8 2013 Nebivolol/HCTZ lowered central SBP by 15.8 +- 14.9 mmHg and DBP 10.5 +- 8.4 mmHg, and with metoprolol/HCTZ by 13.5 +- 12.3 mmHg for SBP and 9.5 +- 6.8 mmHg for DBP (all P < 0.001). Hydrochlorothiazide 10-14 selenium binding protein 1 Homo sapiens 132-135 24061855-3 2013 Based on the recent crystal structure of D3R, we demonstrated that the 4-phenylpiperazine moiety in this class of D3R-selective compounds binds to the conserved orthosteric binding site, whereas the extended aryl amide moiety is oriented toward a divergent secondary binding pocket (SBP). CHEMBL4756418 41-44 selenium binding protein 1 Homo sapiens 283-286 24061855-5 2013 We found that the aryl amide moiety in the SBP differentially induces conformational changes in transmembrane segment 2 and extracellular loop 1 (EL1), which amplify the divergence of the SBP in D3R and D2R. Amides 23-28 selenium binding protein 1 Homo sapiens 43-46 24061855-5 2013 We found that the aryl amide moiety in the SBP differentially induces conformational changes in transmembrane segment 2 and extracellular loop 1 (EL1), which amplify the divergence of the SBP in D3R and D2R. Amides 23-28 selenium binding protein 1 Homo sapiens 188-191 24029865-2 2013 RESULTS: In a multivariable analysis, hypermagnesemia was associated with SBP 6.2 mmHg lower [95% confidence interval (CI) -8.2, -4.2, P < 0.001] than in patients with admission values of serum magnesium 2.6 mg/dl or less. Magnesium 197-206 selenium binding protein 1 Homo sapiens 74-77 24192186-2 2013 The coordination environment of each pentacoordinated Cu(II) centre is square pyramidal (SBP), formed by three water molecules and two carboxylate O atoms from two different (btec)(4-) ligands. Water 111-116 selenium binding protein 1 Homo sapiens 89-92 24192186-4 2013 The alternation of (btec)(4-) ligands and SBP Cu(II) centres leads to the formation of a planar two-dimensional covalent network of parallelograms, parallel to the ab plane. cu(ii) 46-52 selenium binding protein 1 Homo sapiens 42-45 24029865-3 2013 Each mg/dl increase in serum magnesium was associated with a decrease in SBP of 4.3 mmHg (95% CI -5.5, -3.1, P < 0.001). Magnesium 29-38 selenium binding protein 1 Homo sapiens 73-76 23883161-6 2013 Naproxen significantly increased clinic and ambulatory systolic/diastolic BP (SBP/DBP) values in patients treated with ramipril (p < 0.01) or valsartan (p < 0.05), but did not affect aliskiren effects. Naproxen 0-8 selenium binding protein 1 Homo sapiens 78-81 23659386-5 2013 PPf was calculated as pulse pressure divided by mean arterial pressure [Systolic blood pressure - Diastolic blood pressure/Mean arterial pressure (SBP - DBP/MAP)], Hypertensive patients with low CFR (n = 54) compared with those with normal CFR (n = 52) exhibited significantly increased PPf (75.2 +- 11.4 vs. 61.5 +- 6.7 P < 0.001). 2,5-diphenylfuran 0-3 selenium binding protein 1 Homo sapiens 147-150 23883161-7 2013 Also acetaminophen slightly but significantly affected clinic and ambulatory SBP/DBP in all three groups and, surprisingly, it also produced a slight increase in HR (+3.1, +3.3 and +3.4 b/min day-time HR values, for ramipril, valsartan and aliskiren, respectively; p < 0.05). Acetaminophen 5-18 selenium binding protein 1 Homo sapiens 77-80 23883161-6 2013 Naproxen significantly increased clinic and ambulatory systolic/diastolic BP (SBP/DBP) values in patients treated with ramipril (p < 0.01) or valsartan (p < 0.05), but did not affect aliskiren effects. Ramipril 119-127 selenium binding protein 1 Homo sapiens 78-81 23977169-6 2013 The effects of SELENBP1 downregulation on the susceptibility of benzo(a)pyrene (B[a]P)-induced human bronchial epithelial cell transformation were determined. Benzo(a)pyrene 64-78 selenium binding protein 1 Homo sapiens 15-23 23932463-11 2013 Fimasartan 60 mg/d was associated with 53.5% (SBP) and 68.3% (DBP) greater smoothness index scores compared with those with valsartan 80 mg/d (SBP, 1.52 vs. 0.99; DBP, 1.38 vs. 0.82). fimasartan 0-10 selenium binding protein 1 Homo sapiens 46-49 23340855-4 2013 A diagnosis of HTN was made if: (A) MAP or SBP or DBP was >= 1.65 SDS (95th percentile); (B) SBP or DBP was >= 1.65 SDS (95th percentile), during 24-h or daytime or night-time in both definitions. Sodium Dodecyl Sulfate 69-72 selenium binding protein 1 Homo sapiens 43-46 23492672-4 2013 Both confounder-adjusted multivariable and IV analyses suggested that a greater alcohol consumption among those who drank any alcohol resulted in a higher BP [mean difference in SBP per doubling of alcohol consumption among drinkers: 0.76 mmHg (95% CI: 0.63, 0.90) from multivariable analyses and 0.94 mmHg (-3.03, 4.69) from IV analyses; P-value for difference in these results = 0.95]. Alcohols 80-87 selenium binding protein 1 Homo sapiens 178-181 23492672-4 2013 Both confounder-adjusted multivariable and IV analyses suggested that a greater alcohol consumption among those who drank any alcohol resulted in a higher BP [mean difference in SBP per doubling of alcohol consumption among drinkers: 0.76 mmHg (95% CI: 0.63, 0.90) from multivariable analyses and 0.94 mmHg (-3.03, 4.69) from IV analyses; P-value for difference in these results = 0.95]. Alcohols 126-133 selenium binding protein 1 Homo sapiens 178-181 23492672-4 2013 Both confounder-adjusted multivariable and IV analyses suggested that a greater alcohol consumption among those who drank any alcohol resulted in a higher BP [mean difference in SBP per doubling of alcohol consumption among drinkers: 0.76 mmHg (95% CI: 0.63, 0.90) from multivariable analyses and 0.94 mmHg (-3.03, 4.69) from IV analyses; P-value for difference in these results = 0.95]. Alcohols 126-133 selenium binding protein 1 Homo sapiens 178-181 23823816-13 2013 Finally, PLR-DeltaPP was positively correlated with changes in systolic blood pressure (PLR-DeltaSBP) (r(2) = 0.576; P < 0.001) and significantly correlated with dexmedetomidine infusion-induced changes in SBP (r(2) = 0.202; P < 0.05). Dexmedetomidine 165-180 selenium binding protein 1 Homo sapiens 97-100 24082695-15 2013 BuHCl with BH can be attributed to the marked decline in DBP and SBP. Buspirone 0-5 selenium binding protein 1 Homo sapiens 65-68 24082695-15 2013 BuHCl with BH can be attributed to the marked decline in DBP and SBP. Bisoprolol 11-13 selenium binding protein 1 Homo sapiens 65-68 23894368-7 2013 SBP gradient was -4+-3, 14+-9, 10+-4, 0+-11 mmHg in group P and -3+-3, 0+-1, -1+-9, -6+-4 mmHg in group N after induction, during discontinuation of CPB, at the end of surgery and 1 postoperative day respectively. cpb 149-152 selenium binding protein 1 Homo sapiens 0-3 23636018-4 2013 RESULTS: A positive association between total testosterone and BP was revealed in the full sample [SBP: beta per standard deviation (SD) increase: 3.22; pulse pressure (PP): beta per SD increase: 2.30] and among postmenopausal women (DBP: beta per SD increase: 3.33; SBP: beta per SD increase: 7.11; PP: beta per SD increase: 3.77). Testosterone 46-58 selenium binding protein 1 Homo sapiens 99-102 23636018-4 2013 RESULTS: A positive association between total testosterone and BP was revealed in the full sample [SBP: beta per standard deviation (SD) increase: 3.22; pulse pressure (PP): beta per SD increase: 2.30] and among postmenopausal women (DBP: beta per SD increase: 3.33; SBP: beta per SD increase: 7.11; PP: beta per SD increase: 3.77). Testosterone 46-58 selenium binding protein 1 Homo sapiens 267-270 26877914-8 2013 The change in serum sodium concentration was correlated with postdialysis SBP (r=0.304, P<0.005) and pulse pressure (r=0.299, P<0.005). Sodium 20-26 selenium binding protein 1 Homo sapiens 74-77 26877914-9 2013 Predialysis SBP (r = 0.317, P<0.005) and pulse pressure (r=0.324, P=0.001) were also correlated with the postdialysis serum sodium change. Sodium 127-133 selenium binding protein 1 Homo sapiens 12-15 23704933-2 2013 The antitumor function of selenium is thought to be mediated through selenium-binding protein 1 (SELENBP1). Selenium 26-34 selenium binding protein 1 Homo sapiens 69-95 23552121-5 2013 RESULTS: In linear regression models adjusted for age, sex, L-arginine, and ADMA, a positive association was observed between L-homoarginine and SBP [3.90 mmHg per 1-SD increment of L-homoarginine (95% confidence interval, CI 2.28-5.52)] and DBP [1.83 (0.95-2.72)]. N,N-dimethylarginine 76-80 selenium binding protein 1 Homo sapiens 145-148 23552121-5 2013 RESULTS: In linear regression models adjusted for age, sex, L-arginine, and ADMA, a positive association was observed between L-homoarginine and SBP [3.90 mmHg per 1-SD increment of L-homoarginine (95% confidence interval, CI 2.28-5.52)] and DBP [1.83 (0.95-2.72)]. Homoarginine 126-140 selenium binding protein 1 Homo sapiens 145-148 23552121-5 2013 RESULTS: In linear regression models adjusted for age, sex, L-arginine, and ADMA, a positive association was observed between L-homoarginine and SBP [3.90 mmHg per 1-SD increment of L-homoarginine (95% confidence interval, CI 2.28-5.52)] and DBP [1.83 (0.95-2.72)]. Homoarginine 182-196 selenium binding protein 1 Homo sapiens 145-148 23704933-2 2013 The antitumor function of selenium is thought to be mediated through selenium-binding protein 1 (SELENBP1). Selenium 26-34 selenium binding protein 1 Homo sapiens 97-105 23704933-7 2013 17-beta estradiol (E2) treatment of high SELENBP1-expressing ER(+) cell lines led to a down-regulation of SELENBP1, a result that did not occur in ER(-) cell lines. Estradiol 0-17 selenium binding protein 1 Homo sapiens 41-49 23704933-7 2013 17-beta estradiol (E2) treatment of high SELENBP1-expressing ER(+) cell lines led to a down-regulation of SELENBP1, a result that did not occur in ER(-) cell lines. Estradiol 0-17 selenium binding protein 1 Homo sapiens 106-114 23704933-9 2013 In addition, selenium treatment resulted in reduced cell proliferation in endogenous SELENBP1 high cells; however, after knocking-down SELENBP1, we observed no significant reduction in cell proliferation. Selenium 13-21 selenium binding protein 1 Homo sapiens 85-93 23704933-12 2013 These data indicate that SELENBP1 expression is regulated via estrogen and that the cell proliferation inhibition effect of selenium treatment is dependent on the high level of SELENBP1 expression. Selenium 124-132 selenium binding protein 1 Homo sapiens 25-33 23704933-12 2013 These data indicate that SELENBP1 expression is regulated via estrogen and that the cell proliferation inhibition effect of selenium treatment is dependent on the high level of SELENBP1 expression. Selenium 124-132 selenium binding protein 1 Homo sapiens 177-185 23704933-13 2013 Therefore, the expression level of SELENBP1 could be an important marker for predicting survival and effectiveness of selenium supplementation in breast cancer. Selenium 118-126 selenium binding protein 1 Homo sapiens 35-43 22551938-5 2013 between the noninvasively estimated and invasively recorded SBP-C was -2.1+-7.7 mm Hg for A2B(GTF), which was not greater than that of -3.0+-7.7 mm Hg for A2P(GTF) (P<0.01). L-Xylulofuranose-1,2-Borate 90-93 selenium binding protein 1 Homo sapiens 60-63 23633599-2 2013 Crystallographic analysis at 1.75 A resolution shows that the SBP-Tag binds to streptavidin in an unprecedented manner by simultaneously interacting with biotin-binding pockets from two separate subunits. Biotin 154-160 selenium binding protein 1 Homo sapiens 62-65 23633599-3 2013 An N-terminal HVV peptide sequence (residues 12-14) and a C-terminal HPQ sequence (residues 31-33) form the bulk of the direct interactions between the SBP-Tag and the two biotin-binding pockets. Biotin 172-178 selenium binding protein 1 Homo sapiens 152-155 23483240-4 2013 It was noted that diminished SBP1 expression increased gastric cancer cell proliferation and cell migration and decreased cisplatin-induced apoptosis while its overexpression produced the opposite effects. Cisplatin 122-131 selenium binding protein 1 Homo sapiens 29-33 23730647-5 2013 RESULTS: The mean SBP and DBP after taking telmisartan (40 mg) and hydrochlorothiazide (12.5 mg) were 154.88+-9.57 (range 144 to 160) mmHg and 99.37+-2.78 (range 92 to 106). Telmisartan 43-54 selenium binding protein 1 Homo sapiens 18-21 23730647-6 2013 At the end of 4 weeks of being on telmisartan (40 mg) and chlorthalidone (12.5 mg), the mean SBP and DBP were 145.56+-5.12 (range 134 to 158) mmHg and 95.14+-4.27 (range 84 to 100) mmHg. Telmisartan 34-45 selenium binding protein 1 Homo sapiens 93-96 23730647-6 2013 At the end of 4 weeks of being on telmisartan (40 mg) and chlorthalidone (12.5 mg), the mean SBP and DBP were 145.56+-5.12 (range 134 to 158) mmHg and 95.14+-4.27 (range 84 to 100) mmHg. Chlorthalidone 58-72 selenium binding protein 1 Homo sapiens 93-96 23314743-7 2013 RESULTS: Eplerenone significantly decreased more 24-h ambulatory SBP on day 66 than LCI699 on day 29 and the difference between the two treatment was -5.34 [95% confidence interval (CI) -10.30; -0.38)] mmHg (P = 0.027). Eplerenone 9-19 selenium binding protein 1 Homo sapiens 65-68 24083001-7 2013 CONCLUSIONS: We concluded that propofol can reduce SBP, DBP, MAP, HR & cough production at the time of injection but there were no significant changes in these parameters after extubation. Propofol 31-39 selenium binding protein 1 Homo sapiens 51-54 23353631-6 2013 RESULTS: Significant associations or trends were found between rs4149601, rs292449, rs75982813 and rs1008899 and decreases in blood pressure in whites on hydrochlorothiazide, and a significant association was observed with increasing copies of the GC rs4149601-rs292449 haplotype and greater blood pressure response to hydrochlorothiazide in whites (P = 0.0006 and 0.006, SBP and DBP, respectively). Hydrochlorothiazide 319-338 selenium binding protein 1 Homo sapiens 372-375 23073522-6 2013 Systolic and diastolic blood pressure (SBP + DBP) correlated with age, total cholesterol, TG, non-HDL-cholesterol, body mass index and waist circumference; SBP additionally with C-peptide, fasting glycemia; DBP additionally with apoB, homeostasis model assessment (HOMA) and plasminogen activator inhibitor-1. Cholesterol 77-88 selenium binding protein 1 Homo sapiens 39-42 23073522-6 2013 Systolic and diastolic blood pressure (SBP + DBP) correlated with age, total cholesterol, TG, non-HDL-cholesterol, body mass index and waist circumference; SBP additionally with C-peptide, fasting glycemia; DBP additionally with apoB, homeostasis model assessment (HOMA) and plasminogen activator inhibitor-1. Triglycerides 90-92 selenium binding protein 1 Homo sapiens 39-42 23073522-6 2013 Systolic and diastolic blood pressure (SBP + DBP) correlated with age, total cholesterol, TG, non-HDL-cholesterol, body mass index and waist circumference; SBP additionally with C-peptide, fasting glycemia; DBP additionally with apoB, homeostasis model assessment (HOMA) and plasminogen activator inhibitor-1. Cholesterol 102-113 selenium binding protein 1 Homo sapiens 39-42 23073522-6 2013 Systolic and diastolic blood pressure (SBP + DBP) correlated with age, total cholesterol, TG, non-HDL-cholesterol, body mass index and waist circumference; SBP additionally with C-peptide, fasting glycemia; DBP additionally with apoB, homeostasis model assessment (HOMA) and plasminogen activator inhibitor-1. Cholesterol 102-113 selenium binding protein 1 Homo sapiens 156-159 22551938-5 2013 between the noninvasively estimated and invasively recorded SBP-C was -2.1+-7.7 mm Hg for A2B(GTF), which was not greater than that of -3.0+-7.7 mm Hg for A2P(GTF) (P<0.01). glucose tolerance factor 94-97 selenium binding protein 1 Homo sapiens 60-63 22972566-8 2013 SBP was significantly higher in the ketofol group than in the propofol group immediately after PLMA insertion and 5 min after PLMA insertion. Ketofol 36-43 selenium binding protein 1 Homo sapiens 0-3 23442931-3 2013 The aim of this work was to test in vitro the effect of sodium selenite on the human hepatoma cell lines, HepG2 and Huh7, to assess its effect on the expression of GPX1, SELK and SELENBP1 and also to evaluate its action on inflammation determinants such as cytokines. Sodium Selenite 56-71 selenium binding protein 1 Homo sapiens 179-187 23216584-5 2013 RESULTS AND DISCUSSION: There was a similar decrease in SBP and DBP after 6 and 12 months in all groups, even if olmesartan/amlodipine combination gave a major decrease in SBP and DPB compared with amlodipine and olmesartan monotherapies. olmesartan 113-123 selenium binding protein 1 Homo sapiens 172-175 23216584-5 2013 RESULTS AND DISCUSSION: There was a similar decrease in SBP and DBP after 6 and 12 months in all groups, even if olmesartan/amlodipine combination gave a major decrease in SBP and DPB compared with amlodipine and olmesartan monotherapies. Amlodipine 124-134 selenium binding protein 1 Homo sapiens 172-175 22972566-8 2013 SBP was significantly higher in the ketofol group than in the propofol group immediately after PLMA insertion and 5 min after PLMA insertion. Propofol 62-70 selenium binding protein 1 Homo sapiens 0-3 22965458-8 2013 SBP was maintained between 80 and 100% of baseline using bolus doses of phenylephrine. Phenylephrine 72-85 selenium binding protein 1 Homo sapiens 0-3 23235357-7 2013 The correlation coefficient between BP by TC-PDT and that by PTT was 0.98 (P < 0.01) for SBP and 0.93 (P < 0.01) for DBP. Technetium 42-44 selenium binding protein 1 Homo sapiens 92-95 22954201-6 2013 Olmesartan/amlodipine gave a greater decrease in SBP and DPB compared to amlodipine and olmesartan at 6 (P < .05) and 12 months (P < .01). olmesartan 0-10 selenium binding protein 1 Homo sapiens 49-52 22954201-6 2013 Olmesartan/amlodipine gave a greater decrease in SBP and DPB compared to amlodipine and olmesartan at 6 (P < .05) and 12 months (P < .01). Amlodipine 11-21 selenium binding protein 1 Homo sapiens 49-52 23203140-6 2013 However, a subgroup analysis among 130 pre and hypertensive women suggested that soy protein and isoflavones significantly reduced SBP [-4.25%, 95% confidence interval (CI) -7.9 to -0.6%, P = 0.02] and the level of soluble intercellular adhesion molecule (sICAM)-1 (-22.6%, 95% CI -42.8 to -2.3%, P = 0.02) relative to milk protein after 6-month intervention. Isoflavones 97-108 selenium binding protein 1 Homo sapiens 131-134 23246023-2 2013 In this study, the effects of eicosapentaenoic acid (EPA) on C-SBP were compared with pravastatin. Eicosapentaenoic Acid 53-56 selenium binding protein 1 Homo sapiens 63-66 23246023-9 2013 These results suggested that EPA but not pravastatin may reduce cardiac afterload by reducing vascular reflected waves and lowering C-SBP. Eicosapentaenoic Acid 29-32 selenium binding protein 1 Homo sapiens 134-137 23390368-6 2013 RESULTS: Drinking volume was directly associated with higher SBP in a linear dependent manner (an increment of 10 g of alcohol per day increased average SBP by 1 mmHg among both men and women). Alcohols 119-126 selenium binding protein 1 Homo sapiens 61-64 23390368-6 2013 RESULTS: Drinking volume was directly associated with higher SBP in a linear dependent manner (an increment of 10 g of alcohol per day increased average SBP by 1 mmHg among both men and women). Alcohols 119-126 selenium binding protein 1 Homo sapiens 153-156 23321403-5 2013 The olmesartan/amlodipine combination provided a greater decrease of SBP and DPB compared with amlodipine and olmesartan monotherapies. olmesartan 4-14 selenium binding protein 1 Homo sapiens 69-72 23321403-5 2013 The olmesartan/amlodipine combination provided a greater decrease of SBP and DPB compared with amlodipine and olmesartan monotherapies. Amlodipine 15-25 selenium binding protein 1 Homo sapiens 69-72 23011409-9 2013 Treatment with topical CoQ(10) has a positive effect in restoring SBP anatomy and ocular surface stability. coq 23-26 selenium binding protein 1 Homo sapiens 66-69 23044388-10 2013 MTBS values for groups BP (21.3MPa), SBP (31MPa), MDPP (30.1MPa) and SBMDPP (32.3MPa) were significantly higher in specimens treated with NTP than their untreated counterparts B (9.1MPa), SB (14.4MPa), MDP (17.8MPa) and SBMDP (24.1MPa). ntp 138-141 selenium binding protein 1 Homo sapiens 37-40 23545664-5 2013 The equality of variance of systolic (S)BP (i.e., the intragroup standard deviation of SBP) in the irbesartan group was significantly smaller than that observed in the olmesartan group at follow-up. Irbesartan 99-109 selenium binding protein 1 Homo sapiens 87-90 23651970-5 2013 The UA level and the HUA prevalence rate presented a "J" curve relationship with aging and positively correlated with BMI, SBP, DBP, TG, LDL-C, TC and FPG while negatively correlated with HDL-C. Uric Acid 4-6 selenium binding protein 1 Homo sapiens 123-126 23539906-6 2013 Losartan was applied in 31% of untreated and 69% of previously treatment-resistant patients After 8 weeks target blood pressure was achieved in 67.8% (SBP) and in 81.1% (DBP) of patients, respectively. Losartan 0-8 selenium binding protein 1 Homo sapiens 151-154 23373043-12 2012 Rise in SBP and DBP were also statistically significant in placebo and lignocaine group than in fentanyl group (p<0.05). Lidocaine 71-81 selenium binding protein 1 Homo sapiens 8-11 23078461-5 2012 RESULTS: Black men and women showed a 2.8 (P < .001) and 4.0 (P < .001) millimeters mercury increase in SBP, respectively, for each doubling of blood lead. Mercury 90-97 selenium binding protein 1 Homo sapiens 110-113 23078461-8 2012 For example, poor but not nonpoor Black men showed a 4.8 millimeters mercury (P < .001) increase in SBP for each doubling of blood lead. Mercury 69-76 selenium binding protein 1 Homo sapiens 103-106 23373043-12 2012 Rise in SBP and DBP were also statistically significant in placebo and lignocaine group than in fentanyl group (p<0.05). Fentanyl 96-104 selenium binding protein 1 Homo sapiens 8-11 22422177-11 2012 In univariate analysis, age (P < .0001), SBP and DBP (P = .004), and HTN (P = .0003) were associated with WMHV. wmhv 109-113 selenium binding protein 1 Homo sapiens 44-47 23032139-9 2012 Anandamide strongly correlated with blood pressure in sleep apnea patients (r = 0.60 for SBP and r = 0.58 for DBP, P < 0.001). anandamide 0-10 selenium binding protein 1 Homo sapiens 89-92 22922558-7 2012 In contrast, cocaine-induced increases in other vital signs (e.g., SBP, DBP) and subjective effect measures (e.g., paranoia) did not differ between doses. Cocaine 13-20 selenium binding protein 1 Homo sapiens 67-70 22796715-8 2012 After exclusion of them, dairy products (milk especially), fruit and vegetables, fiber and whole-grain food consumption were inversely and linearly associated with SBP (P < 0.04), whereas alcohol intake was positively associated with SBP (P < 10) and DBP (P = 0.005). Alcohols 191-198 selenium binding protein 1 Homo sapiens 237-240 22796715-9 2012 Modification effect of sex was observed for saturated fatty acids intake (positive association with DPB in women) and calcium (negative association with SBP in men). Calcium 118-125 selenium binding protein 1 Homo sapiens 153-156 22660895-4 2012 Patients with metabolic syndrome (MS) had lower activity of gluthatione peroxidase, higher asymmetric dimethyloarginine (ADMA) and oxidized LDL cholesterol (oxyLDL) in comparison to patients without MS. TBARS correlated with left ventricular concentric hypertrophy, cIMT, albuminuria and SBP/24 h. ADMA and oxyLDL correlated with CRP and TG/HDL ratio. Thiobarbituric Acid Reactive Substances 203-208 selenium binding protein 1 Homo sapiens 288-291 22990355-2 2012 We determined the effects of SBP lowering to 160 mmHg or more using intravenous nicardipine for acute ICH patients. Nicardipine 80-91 selenium binding protein 1 Homo sapiens 29-32 22990355-12 2012 CONCLUSION: SBP lowering to 160 mmHg or less using nicardipine appears to be well tolerated and feasible for acute ICH. Nicardipine 51-62 selenium binding protein 1 Homo sapiens 12-15 30705699-10 2012 The magnitude of fall in SBP, DBP and MAP was greater in the labetalol group compared with the nifedipine group (P < 0.05). Labetalol 61-70 selenium binding protein 1 Homo sapiens 25-28 30705699-14 2012 Intravenous labetalol may have benefits because it is more effective in reducing the SBP, DBP and MAP to target levels with a lower number of doses. Labetalol 12-21 selenium binding protein 1 Homo sapiens 85-88 22990352-6 2012 When felodipine was compared to placebo, the benefit of a lower SBP/DBP caused by felodipine was evident in the no-add-on patients (hazard ratio 0.45-0.68, P always <0.001), but it was lost in the add-on group (hazard ratio 0.91-1.17). Felodipine 5-15 selenium binding protein 1 Homo sapiens 64-67 22990352-6 2012 When felodipine was compared to placebo, the benefit of a lower SBP/DBP caused by felodipine was evident in the no-add-on patients (hazard ratio 0.45-0.68, P always <0.001), but it was lost in the add-on group (hazard ratio 0.91-1.17). Felodipine 82-92 selenium binding protein 1 Homo sapiens 64-67 22621845-7 2012 Using stepwise regression analysis with Age, BMI, SBP, DBP, MBP: Dtf was dependent with age (P<10(-4)) and SBP (P<0.01); PWVtf with age (P<0.0001), SBP (P<0.01) and DBP (P<0.05); pOpscore( ) was dependent only to age (P<10(-4)). dtf 65-68 selenium binding protein 1 Homo sapiens 50-53 28348679-6 2012 Mean reduction in sBP and dBP with aliskiren 150 mg/d was 6.7 +- 5.4 mmHg and 5.4 +- 4.8 mmHg, respectively. aliskiren 35-44 selenium binding protein 1 Homo sapiens 18-21 28348679-7 2012 Mean reduction in sBP and dBP with aliskiren 300 mg/d was 8.6 +- 6.3 mmHg and 6.0 +- 4.9 mmHg, respectively. aliskiren 35-44 selenium binding protein 1 Homo sapiens 18-21 23734440-7 2012 Regression analysis of mercury versus aneroid showed regression line (Y = 9.52 + 0.95X for SBP, Y = 0.36 + 0.96X for DBP) significantly different from line of equality (P < 0.001). Mercury 23-30 selenium binding protein 1 Homo sapiens 91-94 22573127-6 2012 Olmesartan medoxomil reduced the SBP morning rise [-2.8 (-4.9, -0.8) mmHg], whereas ramipril did not [+1.5 (-0.6, +3.6) mmHg; P = 0.004 between-treatments]. olmesartan 0-10 selenium binding protein 1 Homo sapiens 33-36 22573127-6 2012 Olmesartan medoxomil reduced the SBP morning rise [-2.8 (-4.9, -0.8) mmHg], whereas ramipril did not [+1.5 (-0.6, +3.6) mmHg; P = 0.004 between-treatments]. medoxomil 11-20 selenium binding protein 1 Homo sapiens 33-36 22573127-7 2012 Five hundred and eighty-two patients with sustained hypertension (office and 24-h ambulatory hypertension) showed the largest antihypertensive effect, with between-treatment differences still in favor of olmesartan medoxomil [SBP: 2.1 (3.9, 0.4), P = 0.019; DBP: 1.2 (2.3, 0.1), P = 0.032]. olmesartan 204-214 selenium binding protein 1 Homo sapiens 226-229 22499291-8 2012 Visit-to-visit intraindividual clinic SBP variability was only slightly lower on calcium antagonist than on beta-blocker treatment but little or no between-treatment difference was found for visit-to-visit clinic DBP and ambulatory SBP/DBP particularly in patients under monotherapy throughout the study. Calcium 81-88 selenium binding protein 1 Homo sapiens 38-41 22595957-7 2012 Further adjustment for vitamin D explained 14 and 6% of these SBP and DBP differences, respectively. Vitamin D 23-32 selenium binding protein 1 Homo sapiens 62-65 22595957-9 2012 Variation in vitamin D explained 7 and 4% of these SBP and DBP differences. Vitamin D 13-22 selenium binding protein 1 Homo sapiens 51-54 22595957-11 2012 Vitamin D explained 25 and 17% of the variations in SBP and DBP, respectively, resulting in odds ratio of 1.9 (1.3-2.9) and 2.9 (2.0-4.3), respectively. Vitamin D 0-9 selenium binding protein 1 Homo sapiens 52-55 22573127-4 2012 RESULTS: In 715 patients with valid baseline and end-of-treatment recordings baseline-adjusted 24-h SBP and DBP reductions were greater with olmesartan medoxomil (n = 356) than with ramipril (n = 359) [between-treatment differences and 95% confidence interval (CI), SBP: 2.2 (3.8, 0.6), P = 0.006; DBP: 1.3 (2.2, 0.3), P = 0.009]. olmesartan 141-151 selenium binding protein 1 Homo sapiens 100-103 22573127-4 2012 RESULTS: In 715 patients with valid baseline and end-of-treatment recordings baseline-adjusted 24-h SBP and DBP reductions were greater with olmesartan medoxomil (n = 356) than with ramipril (n = 359) [between-treatment differences and 95% confidence interval (CI), SBP: 2.2 (3.8, 0.6), P = 0.006; DBP: 1.3 (2.2, 0.3), P = 0.009]. medoxomil 152-161 selenium binding protein 1 Homo sapiens 100-103 22072582-2 2012 In addition, Se-containing proteins including members of the glutathione peroxidase (GPx) family and Selenium-Binding Protein 1 (SBP1) have been linked to either cancer risk or development. Selenium 13-15 selenium binding protein 1 Homo sapiens 101-127 22072582-2 2012 In addition, Se-containing proteins including members of the glutathione peroxidase (GPx) family and Selenium-Binding Protein 1 (SBP1) have been linked to either cancer risk or development. Selenium 13-15 selenium binding protein 1 Homo sapiens 129-133 23210033-6 2012 In each subgroups of Fisher grade and different dose, SBP/DBP also decreased after the use of nicardipine. Nicardipine 94-105 selenium binding protein 1 Homo sapiens 54-57 23210033-8 2012 Furthermore, controlling blood pressure was more effective when injecting higher dose of nicardipine in higher SBP group rather than injecting lower dose in lower SBP group, and it also was statistically significant (p < 0.05). Nicardipine 89-100 selenium binding protein 1 Homo sapiens 111-114 22621845-7 2012 Using stepwise regression analysis with Age, BMI, SBP, DBP, MBP: Dtf was dependent with age (P<10(-4)) and SBP (P<0.01); PWVtf with age (P<0.0001), SBP (P<0.01) and DBP (P<0.05); pOpscore( ) was dependent only to age (P<10(-4)). dtf 65-68 selenium binding protein 1 Homo sapiens 110-113 22621845-7 2012 Using stepwise regression analysis with Age, BMI, SBP, DBP, MBP: Dtf was dependent with age (P<10(-4)) and SBP (P<0.01); PWVtf with age (P<0.0001), SBP (P<0.01) and DBP (P<0.05); pOpscore( ) was dependent only to age (P<10(-4)). dtf 65-68 selenium binding protein 1 Homo sapiens 110-113 22450868-8 2012 Higher FMD correlated with lower brachial baseline diameter (P < 0.001), BMI (P = 0.03) and SBP (P = 0.03) in the Asp-carriers, but not in Glu-homozygotes. Aspartic Acid 117-120 selenium binding protein 1 Homo sapiens 95-98 22406464-5 2012 When we divided participants by their time of candesartan administration, the relationship between the decrease in log-transformed BNP and asleep SBP was still significant in both the awakening-dosing group (beta = 0.21, P = 0.028) and the bedtime-dosing group (beta = 0.21, P = 0.029). candesartan 46-57 selenium binding protein 1 Homo sapiens 146-149 22441345-5 2012 From EoA to day 7 of treatment withdrawal (end of withdrawal, EoW), the least squares mean increase in 24-h mean ambulatory SBP was smaller for aliskiren (2.7 mmHg) vs. telmisartan (6.5 mmHg). aliskiren 144-153 selenium binding protein 1 Homo sapiens 124-127 22242212-15 2012 Elevated SBP/DBP and uncontrolled hypertension were associated with increasing BMI, LDL-cholesterol, triglycerides, and HbA1c, both globally and regionally. Cholesterol 88-99 selenium binding protein 1 Homo sapiens 9-12 22104030-12 2012 Furthermore, VO2, RER, HR, VE, RPE-Br, RPE-Legs, SF, and SBP while walking in water were significantly higher with a water current than without (P < .05). Water 117-122 selenium binding protein 1 Homo sapiens 57-60 22919632-1 2012 Lipoproteins fulfill diverse roles in antibiotic resistance, adhesion, protein secretion, signaling and sensing, and many also serve as the substrate binding protein (SBP) partner to ABC transporters for the acquisition of a diverse array of nutrients including peptides, sugars, and scarcely abundant metals. Peptides 262-270 selenium binding protein 1 Homo sapiens 140-165 22919632-1 2012 Lipoproteins fulfill diverse roles in antibiotic resistance, adhesion, protein secretion, signaling and sensing, and many also serve as the substrate binding protein (SBP) partner to ABC transporters for the acquisition of a diverse array of nutrients including peptides, sugars, and scarcely abundant metals. Peptides 262-270 selenium binding protein 1 Homo sapiens 167-170 22919632-1 2012 Lipoproteins fulfill diverse roles in antibiotic resistance, adhesion, protein secretion, signaling and sensing, and many also serve as the substrate binding protein (SBP) partner to ABC transporters for the acquisition of a diverse array of nutrients including peptides, sugars, and scarcely abundant metals. Sugars 272-278 selenium binding protein 1 Homo sapiens 140-165 22919632-1 2012 Lipoproteins fulfill diverse roles in antibiotic resistance, adhesion, protein secretion, signaling and sensing, and many also serve as the substrate binding protein (SBP) partner to ABC transporters for the acquisition of a diverse array of nutrients including peptides, sugars, and scarcely abundant metals. Sugars 272-278 selenium binding protein 1 Homo sapiens 167-170 22372508-7 2012 Compared with dual therapy, the add-on effect of valsartan was significantly greater than that of olmesartan, the difference being more evident for nighttime SBP/DBP values (-3.3 (95% CI 0.44 - 3.51)/3.0 (95% CI 0.59 - 3.34) mm Hg, p < 0.01). Valsartan 49-58 selenium binding protein 1 Homo sapiens 158-161 22563335-11 2012 CONCLUSION: The antihypertensive action of efonidipine was characterized by a slow recovery of the SBP decrease at a constant rate (2.1 mm Hg/h) and a non-administration time dependent reduction in 24-hour HR. efonidipine 43-54 selenium binding protein 1 Homo sapiens 99-102 22439158-13 2012 For SMBP alone versus usual care, the strength of evidence is moderate and supports a lower BP with SMBP (SBP/DBP -3.1/-2.0 mmHg at 6 months). smbp 100-104 selenium binding protein 1 Homo sapiens 106-109 22439158-14 2012 For SMBP plus additional support versus usual care, the strength of evidence is high and supports a lower BP with SMBP use (SBP/DBP -3.4 to -8.9/-1.9 to -4.4 mmHg) up to 12 months. smbp 4-8 selenium binding protein 1 Homo sapiens 124-127 22439158-14 2012 For SMBP plus additional support versus usual care, the strength of evidence is high and supports a lower BP with SMBP use (SBP/DBP -3.4 to -8.9/-1.9 to -4.4 mmHg) up to 12 months. smbp 114-118 selenium binding protein 1 Homo sapiens 124-127 22177521-4 2012 RESULTS: Both heroin-abstinent groups showed increased heroin craving, SC, MEG, HR, SBP and LBP after exposure to heroin-related video, compared to the control group and compared to exposure to the neutral video. Heroin 14-20 selenium binding protein 1 Homo sapiens 84-87 22410289-14 2012 Valsartan monotherapy and valsartan combined with pitavastatin were associated with significantly lower SBP and DBP compared with baseline (both, P < 0.05), although no significant changes in PR were observed. Valsartan 0-9 selenium binding protein 1 Homo sapiens 104-107 22410289-14 2012 Valsartan monotherapy and valsartan combined with pitavastatin were associated with significantly lower SBP and DBP compared with baseline (both, P < 0.05), although no significant changes in PR were observed. Valsartan 26-35 selenium binding protein 1 Homo sapiens 104-107 22410289-14 2012 Valsartan monotherapy and valsartan combined with pitavastatin were associated with significantly lower SBP and DBP compared with baseline (both, P < 0.05), although no significant changes in PR were observed. pitavastatin 50-62 selenium binding protein 1 Homo sapiens 104-107 22138666-9 2012 Few studies have evaluated changes in systolic and diastolic BP (SBP and DBP, respectively) measurements by arsenic exposure levels, and those studies reported inconclusive findings. Arsenic 108-115 selenium binding protein 1 Homo sapiens 65-68 21603903-11 2012 The sodium restriction group achieved significantly more reduction in SBP (-11.1 mmHg vs. -5.0 mmHg, P = 0.022), DBP (-9.4 mmHg vs. -2.1 mmHg, P = 0.009), and urine protein excretion [-465 (-855 to -340) mg/day vs. -150 (-570 to 40) mg/day, P = 0.024]. Sodium 4-10 selenium binding protein 1 Homo sapiens 70-73 21603903-12 2012 A positive correlation was observed between the change of 24-h UNa and the change of SBP (r = 0.450, P = 0.047) in the sodium restriction group. Sodium 119-125 selenium binding protein 1 Homo sapiens 85-88 22252478-7 2012 The baPWV correlated significantly to variables such as age, sex, baseline SBP and DBP, pulse pressure, maximal oxygen consumption (VO(2max)), SBP at stage 1, at stage 2 and peak exercise and hemoglobin A1c (HbA1c). bapwv 4-9 selenium binding protein 1 Homo sapiens 75-78 22252478-7 2012 The baPWV correlated significantly to variables such as age, sex, baseline SBP and DBP, pulse pressure, maximal oxygen consumption (VO(2max)), SBP at stage 1, at stage 2 and peak exercise and hemoglobin A1c (HbA1c). bapwv 4-9 selenium binding protein 1 Homo sapiens 143-146 22252478-8 2012 In multiple regression model, SBP at stage 1 had a significant association with baPWV after an adjustment with age, sex, VO(2max) and SBP at rest, current smoking and HbA1c. bapwv 80-85 selenium binding protein 1 Homo sapiens 30-33 22252478-8 2012 In multiple regression model, SBP at stage 1 had a significant association with baPWV after an adjustment with age, sex, VO(2max) and SBP at rest, current smoking and HbA1c. bapwv 80-85 selenium binding protein 1 Homo sapiens 134-137 22252478-9 2012 For every 10 mmHg increase in exercise SBP, baPWV increased by 18 +- 0.3 cm/s (P < 0.001). bapwv 44-49 selenium binding protein 1 Homo sapiens 39-42 22252478-10 2012 CONCLUSION: In normotensive individuals, increased arterial stiffness, as reflected by baPWV, is accompanied by higher SBP at the early stage of treadmill exercise test. bapwv 87-92 selenium binding protein 1 Homo sapiens 119-122 22252480-4 2012 RESULTS: In a sex, BMI, smoking habit, physical activity level and serum creatinine adjusted model, low-density lipoprotein-cholesterol (LDL-C) appears to be significantly related to SBP (P < 0.001), DBP (P = 0.026), and pulse pressure (PP) (P < 0.001). Creatinine 73-83 selenium binding protein 1 Homo sapiens 183-186 22277139-2 2012 A total of 4649 patients diagnosed retrospectively with DTTH, defined as systolic/diastolic blood pressure (SBP/DBP) >=140/90 mm Hg despite use of at least 3 antihypertensive drugs during the month preceding the baseline visit comprised the intention-to-treat (ITT) cohort. dtth 56-60 selenium binding protein 1 Homo sapiens 108-111 22277139-5 2012 After EBT for 6 months, SBP/DBP in DTTH was 138.8+-12.2/81.9+-7.4 (DeltaSBP-26+-15.7; DeltaDBP-11.4+-9.8); PP was 57.0+-10.8 (DeltaPP-14.5+-13.8) (all P<.001 vs baseline and non-DTTH group). ebt 6-9 selenium binding protein 1 Homo sapiens 24-27 22277139-5 2012 After EBT for 6 months, SBP/DBP in DTTH was 138.8+-12.2/81.9+-7.4 (DeltaSBP-26+-15.7; DeltaDBP-11.4+-9.8); PP was 57.0+-10.8 (DeltaPP-14.5+-13.8) (all P<.001 vs baseline and non-DTTH group). dtth 35-39 selenium binding protein 1 Homo sapiens 24-27 22845729-6 2012 Also, BPb was negatively correlated with serum Ca and, P, and positively correlated with systolic and diastolic blood pressures in pregnancy (r = -.804 for Ca, r = -.728 for P, r = .908 for SBP, and r = .842 for DBP) and preeclampsia (p < .01). bpb 6-9 selenium binding protein 1 Homo sapiens 190-193 22242212-15 2012 Elevated SBP/DBP and uncontrolled hypertension were associated with increasing BMI, LDL-cholesterol, triglycerides, and HbA1c, both globally and regionally. Triglycerides 101-114 selenium binding protein 1 Homo sapiens 9-12 21556814-13 2012 Results suggest that PTT can be used for measuring absolute SBP when performing an individual correction for the offset of the BP-PWV relation. Benzo(a)pyrene 61-63 selenium binding protein 1 Homo sapiens 21-24 23320025-18 2012 There is encouraging evidence of BBTD for lowering SBP, but evidence remains weak. bbtd 33-37 selenium binding protein 1 Homo sapiens 51-54 22263105-6 2012 Although trait anxiety was associated with SBP response to AR and not CP, it was not a significant predictor of reactivity in our models. Argon 59-61 selenium binding protein 1 Homo sapiens 43-46 22449659-9 2012 CONCLUSION: Age, SBP, triglycerides, and cholesterol levels are independently and positively associated with baPWV. bapwv 109-114 selenium binding protein 1 Homo sapiens 17-20 22171903-5 2012 RESULTS: EDP reduces over time in both datasets; the percentage of patients with a zero EDP declined from 70% to 27% and 68% to 26% for SBP and DBP respectively. 2-ethyl-3,5-dimethylpyrazine 9-12 selenium binding protein 1 Homo sapiens 136-139 22970383-9 2012 A negative significant correlation was found between potency score and HbA1c (r: 0.20,P: 0.01), FPG (r: 0.17, P: 0.03) and SBP (r: 0.18, P: 0.02) but not between other risk factors such as lipid profile, BMI, and serum testosterone level. Testosterone 219-231 selenium binding protein 1 Homo sapiens 123-126 22844584-5 2012 Treatment with telmisartan-HCTZ induced significantly greater reductions in BP (-31.1/-18.3 mm Hg) than valsartan-HCTZ (-28.4/-16.3 mm Hg; SBP P = 0.0265, diastolic BP P = 0.0041). Telmisartan 15-26 selenium binding protein 1 Homo sapiens 139-142 22844584-5 2012 Treatment with telmisartan-HCTZ induced significantly greater reductions in BP (-31.1/-18.3 mm Hg) than valsartan-HCTZ (-28.4/-16.3 mm Hg; SBP P = 0.0265, diastolic BP P = 0.0041). Hydrochlorothiazide 27-31 selenium binding protein 1 Homo sapiens 139-142 22493905-6 2012 After adjusting for BMI, SBP, DBP, UA, FBG and CCr, the multiple regression analysis showed that the levels of TC and TG decreased by 0.097 mmol/L and 0.087 mmol/L respectively every 10 years older, while the level of HDL-c increased by 0.113 mmol/L. Technetium 111-113 selenium binding protein 1 Homo sapiens 25-28 22892483-9 2012 Univariate analysis showed that age, BMI, TB, ALT, GGT, Cho, SBP, DBP, UA, and TC were significantly associated with baPWV in men. bapwv 117-122 selenium binding protein 1 Homo sapiens 61-64 22892483-10 2012 In women, age, BMI, current smoker, Cho, SBP, DBP, UA, TC, TG, HDL-C, and LDL-C were significantly associated with baPWV. bapwv 115-120 selenium binding protein 1 Homo sapiens 41-44 22496969-5 2012 Univariate regressions showed that changes in urinary sodium/potassium ratio (beta = 1.99) and plasma renin activity (beta = -15.78) and percent change in plasma nitrite after hyperemia were associated with SBP changes at week one (all P < 0.05). Sodium 54-60 selenium binding protein 1 Homo sapiens 207-210 22496969-5 2012 Univariate regressions showed that changes in urinary sodium/potassium ratio (beta = 1.99) and plasma renin activity (beta = -15.78) and percent change in plasma nitrite after hyperemia were associated with SBP changes at week one (all P < 0.05). Potassium 61-70 selenium binding protein 1 Homo sapiens 207-210 23098346-6 2012 According to multivariate analysis, dose selection of losartan was determined by an attending physician, mainly (85% according to the estimate of the explained variance), based on the baseline SBP. Losartan 54-62 selenium binding protein 1 Homo sapiens 193-196 23098346-7 2012 As a result of treatment (41 to 53% of patients received losartan only or in combination with HCTZ) SBP decrease in the groups ranged from 20 to 38 mm Hg, DBP - from 10 to 17 mm Hg, the target blood pressure is achieved in 29-66% of patients. Losartan 57-65 selenium binding protein 1 Homo sapiens 100-103 23098346-7 2012 As a result of treatment (41 to 53% of patients received losartan only or in combination with HCTZ) SBP decrease in the groups ranged from 20 to 38 mm Hg, DBP - from 10 to 17 mm Hg, the target blood pressure is achieved in 29-66% of patients. Hydrochlorothiazide 94-98 selenium binding protein 1 Homo sapiens 100-103 22157325-11 2012 In this uncontrolled, high-risk treated hypertensive population, SBP and DBP levels recorded during treatment with aliskiren were consistently lower than those recorded at entry visits in a context of a very low rate of reported side-effects. aliskiren 115-124 selenium binding protein 1 Homo sapiens 65-68 22496969-5 2012 Univariate regressions showed that changes in urinary sodium/potassium ratio (beta = 1.99) and plasma renin activity (beta = -15.78) and percent change in plasma nitrite after hyperemia were associated with SBP changes at week one (all P < 0.05). Nitrites 162-169 selenium binding protein 1 Homo sapiens 207-210 23071713-6 2012 The pooled estimate for CDSS versus control group differences in SBP (mm of Hg) was - 0.99 (95% CI -3.02 to 1.04 mm of Hg; I(2) = 0; p = 0.851). cdss 24-28 selenium binding protein 1 Homo sapiens 65-68 22493905-6 2012 After adjusting for BMI, SBP, DBP, UA, FBG and CCr, the multiple regression analysis showed that the levels of TC and TG decreased by 0.097 mmol/L and 0.087 mmol/L respectively every 10 years older, while the level of HDL-c increased by 0.113 mmol/L. Triglycerides 118-120 selenium binding protein 1 Homo sapiens 25-28 21970937-7 2011 In regression models with similar adjustments, with 1-SD increase in central SBP (16.7 mmHg), E/A ratio significantly decreased by 5.5 +- 1.2% and DTE significantly increased by 4.66 +- 1.22 ms (P < 0.001). Dithioerythritol 147-150 selenium binding protein 1 Homo sapiens 77-80 21939225-4 2011 The most prominent observation was the consistent positive correlations between different forms of triantennary glycans and negative correlations between glycans containing core-fucose with MetS components including BMI, SBP, DBP, and fasting plasma glucose (FPG) simultaneously. Polysaccharides 154-161 selenium binding protein 1 Homo sapiens 221-224 22071811-7 2011 The effect of sodium reduction in normotensive Blacks was SBP -4.02 mmHg (95% CI:-7.37, -0.68; p=0.002), DBP -2.01 mmHg (95% CI:-4.37, 0.35; p=0.09). Sodium 14-20 selenium binding protein 1 Homo sapiens 58-61 22071811-8 2011 The effect of sodium reduction in normotensive Asians was SBP -1.27 mmHg (95% CI: -3.07, 0.54; p=0.17), DBP -1.68 mmHg (95% CI:-3.29, -0.06; p=0.04). Sodium 14-20 selenium binding protein 1 Homo sapiens 58-61 22071811-9 2011 The effect of sodium reduction in hypertensive Caucasians was SBP -5.48 mmHg (95% CI: -6.53, -4.43; p<0.00001), DBP -2.75 mmHg (95% CI: -3.34, -2.17; p<0.00001). Sodium 14-20 selenium binding protein 1 Homo sapiens 62-65 22071811-10 2011 The effect of sodium reduction in hypertensive Blacks was SBP -6.44 mmHg (95% CI:-8.85, -4.03; p=0.00001), DBP -2.40 mmHg (95% CI:-4.68, -0.12; p=0.04). Sodium 14-20 selenium binding protein 1 Homo sapiens 58-61 22025233-10 2011 In the subset of patients who underwent ambulatory BP assessments, valsartan provided greater reductions than enalapril in mean 24-h SBP (valsartan: -9.8 mmHg, enalapril: -7.2 mmHg: P = 0.03). Valsartan 67-76 selenium binding protein 1 Homo sapiens 133-136 21939225-6 2011 In the multivariate analysis, the level of monosialylated glycans (structure loadings = -0.776) was the most correlated with the MetS related risk factors, especially with SBP (structure loadings = 0.907). Polysaccharides 58-65 selenium binding protein 1 Homo sapiens 172-175 22340226-9 2011 Stepwise regression analysis showed that erythrocytic H(2)S production was correlated with sBP, TG, HDL-C, low density lipoprotein cholesterol (LDL-C) and blood urea nitrogen (BUN) and serum H(2)S was correlated with dBP and TG. Hydrogen Sulfide 54-59 selenium binding protein 1 Homo sapiens 91-94 22340226-7 2011 The erythrocytic H(2)S production was associated with increased systolic blood pressure (sBP), diastolic blood pressure (dBP), age, BMI, level of C-reactive protein (CRP), as well as triglycerides (TG) and high density lipoprotein cholesterol (HDL-C). Hydrogen Sulfide 17-22 selenium binding protein 1 Homo sapiens 89-92 22848296-5 2011 Furthermore, a significant correlation was found between selenium levels and human selenium binding protein-1 (SELENBP1) down-regulation in the liver. Selenium 57-65 selenium binding protein 1 Homo sapiens 83-109 21897291-7 2011 Significant inverse correlations were found between nitric oxide production and disease duration, SBP, and DBP. Nitric Oxide 52-64 selenium binding protein 1 Homo sapiens 98-101 21958068-4 2011 RESULTS: Amlodipine-telmisartan combination induced greater SBP/DBP reduction (-28.1/21.7 mmHg, p < 0.0001 vs baseline) compared with monotherapy with both amlodipine and telmisartan. Amlodipine 9-19 selenium binding protein 1 Homo sapiens 60-63 21958068-4 2011 RESULTS: Amlodipine-telmisartan combination induced greater SBP/DBP reduction (-28.1/21.7 mmHg, p < 0.0001 vs baseline) compared with monotherapy with both amlodipine and telmisartan. Telmisartan 20-31 selenium binding protein 1 Homo sapiens 60-63 22848296-5 2011 Furthermore, a significant correlation was found between selenium levels and human selenium binding protein-1 (SELENBP1) down-regulation in the liver. Selenium 57-65 selenium binding protein 1 Homo sapiens 111-119 21699274-6 2011 RESULTS: Mean (+- SD) systolic (SBP) and diastolic (DBP) BP were reduced by amlodipine by 22.1 mmHg (+- 13.2) and 10.4 mmHg (+- 7.5), respectively (p < 0.001). Amlodipine 76-86 selenium binding protein 1 Homo sapiens 32-35 22321230-5 2011 Central SBP significantly correlated to the application of ACEI (beta = -0.07, P = 0.02), ARB (beta = -0.08, P = 0.01) and CCB (beta = -0.15, P < 0.05). acei 59-63 selenium binding protein 1 Homo sapiens 8-11 21888642-9 2011 Replacement of NaCl with Smart Salt resulted in a significant reduction in SBP over 8 weeks (-7.5 mmHg; p = 0.016). Sodium Chloride 15-19 selenium binding protein 1 Homo sapiens 75-78 21888642-9 2011 Replacement of NaCl with Smart Salt resulted in a significant reduction in SBP over 8 weeks (-7.5 mmHg; p = 0.016). Salts 31-35 selenium binding protein 1 Homo sapiens 75-78 21888642-12 2011 CONCLUSIONS: The substitution of Smart Salt for Regular salt in subjects with high normal or mildly elevated BP resulted in a significant reduction in their daily sodium intake as well as a reduction in SBP. Salts 39-43 selenium binding protein 1 Homo sapiens 203-206 21888642-12 2011 CONCLUSIONS: The substitution of Smart Salt for Regular salt in subjects with high normal or mildly elevated BP resulted in a significant reduction in their daily sodium intake as well as a reduction in SBP. Salts 56-60 selenium binding protein 1 Homo sapiens 203-206 21799445-6 2011 For example, the number of G alleles of the N554S missense mutation (rs5527) of NR3C2 was significantly associated with greater SBP responses to potassium intervention; mean [95% confidence interval (CI)] responses (mmHg) were -3.33 (-3.65 to -3.02) for genotype A/A and -5.47 (-6.64 to -4.29) for A/G, respectively (P value = 0.0004). Potassium 145-154 selenium binding protein 1 Homo sapiens 128-131 21799445-7 2011 In addition, the number of C alleles of the A1166C variant (rs5186) in AGTR1 was significantly and inversely associated with SBP responses to potassium intervention; mean (95% CI) responses were -3.55 (-3.87 to -3.24) for genotype A/A, -2.45 (-3.27 to -1.62) for A/C, and 3.25 (-5.73 to 12.23) for CC (P value = 0.003). Potassium 142-151 selenium binding protein 1 Homo sapiens 125-128 21451591-4 2011 RESULTS: With adjustments for confounders, interactions between ARR and urinary Na(+)/K(+) were independently associated with systolic BP (SBP) (P < 0.0001), an effect that was accounted for by interactions between serum aldosterone concentrations and urinary Na(+)/K(+) (P < 0.0001), but not between plasma renin concentrations and urinary Na(+)/K(+) (P = 0.52). Aldosterone 224-235 selenium binding protein 1 Homo sapiens 139-142 21841500-6 2011 RESULTS: Higher doses of valsartan (640 mg) demonstrated additional reductions in SBP among the prompt responders and led to greater SBP reductions from baseline (19.8 mmHg) compared with valsartan 160 (14.4 mmHg, P < 0.05) and 320 mg (16.5 mmHg). Valsartan 25-34 selenium binding protein 1 Homo sapiens 82-85 21841500-6 2011 RESULTS: Higher doses of valsartan (640 mg) demonstrated additional reductions in SBP among the prompt responders and led to greater SBP reductions from baseline (19.8 mmHg) compared with valsartan 160 (14.4 mmHg, P < 0.05) and 320 mg (16.5 mmHg). Valsartan 25-34 selenium binding protein 1 Homo sapiens 133-136 21691677-6 2011 Mean systolic (SBP) and diastolic blood pressure (DBP) for SMBP were 134 (+- 15.71) mmHg and 79.32 (+- 12.38) mmHg. smbp 59-63 selenium binding protein 1 Homo sapiens 15-18 21332412-12 2011 Furthermore, a significant reduction in 24-h SBP and DBP was observed in patients receiving barnidipine but not in those receiving diuretic. mepirodipine 92-103 selenium binding protein 1 Homo sapiens 45-48 21602709-10 2011 Candesartan reduced combined macrovascular and microvascular complication risk; the age and baseline SBP overall adjusted hazard ratio for candesartan vs. placebo was 0.85 [95% confidence interval (CI) 0.72-0.99], P = 0.040, reflecting hazard ratios of 0.86 (0.66-1.13) for baseline normotensive individuals and 0.83 (0.68-1.02) for hypertensive patients. candesartan 139-150 selenium binding protein 1 Homo sapiens 101-104 21632140-9 2011 CONCLUSION: The blunted nocturnal decline in SBP during the early morning hours is associated with chronically elevated blood glucose in non-dipper African men. Glucose 126-133 selenium binding protein 1 Homo sapiens 45-48 21660675-10 2011 Further, the improvements in the ratio of T/P of SBP & DBP and in the level of NO and ET-1 in the treatment group were more significant than those in the control group (P<0.05). Phosphorus 44-45 selenium binding protein 1 Homo sapiens 49-52 21660675-10 2011 Further, the improvements in the ratio of T/P of SBP & DBP and in the level of NO and ET-1 in the treatment group were more significant than those in the control group (P<0.05). Adenosine Monophosphate 54-57 selenium binding protein 1 Homo sapiens 49-52 21346624-6 2011 RESULTS: When stratified by genotypes, patients carrying allele C of single-neucleotide polymorphism (SNP) rs5186 showed positive association between irbesartan concentration and BP response [SBP: beta +- SE=6.1 +- 2.3 with false discovery rate (FDR) P=0.029; DBP: beta +- SE=2.7 +- 1.0 with FDR P=0.029], but this was not seen in patients with AA genotype. Irbesartan 150-160 selenium binding protein 1 Homo sapiens 192-195 21372742-8 2011 Total glutamate intake was also positively associated with an increase in SBP. Glutamic Acid 6-15 selenium binding protein 1 Homo sapiens 74-77 21346624-7 2011 There was a significant interaction between plasma irbesartan concentration and SNP rs5186 on SBP response (interaction P=0.0335) and DBP response (interaction P=0.0190). Irbesartan 51-61 selenium binding protein 1 Homo sapiens 94-97 21346624-8 2011 There also were significant interactions between plasma irbesartan concentration and hap3, hap5 and hap6 (constructed by four genotyped SNPs) on SBP response (FDR P<0.001), but not on DBP response. Irbesartan 56-66 selenium binding protein 1 Homo sapiens 145-148 21404246-0 2011 Construction of a novel glucose-sensing molecule based on a substrate-binding protein for intracellular sensing. Glucose 24-31 selenium binding protein 1 Homo sapiens 60-85 21338716-3 2011 Since the structure-function relationships of SELENBP1 are unknown, we have performed computational and experimental studies to have insight on the structural features of this protein focusing our attention on the properties of cysteines to assess their ability to interact with selenium. Selenium 279-287 selenium binding protein 1 Homo sapiens 46-54 21338716-6 2011 Our studies demonstrate that (i) SELENBP1 is an alpha-beta protein with some loop regions characterized by the presence of intrinsically unordered segments, (ii) only one cysteine (Cys57) is enough exposed to solvent, located on a loop and surrounded by charged and hydrophobic residues, and can be the cysteine able to bind the selenium. Cysteine 171-179 selenium binding protein 1 Homo sapiens 33-41 21338716-6 2011 Our studies demonstrate that (i) SELENBP1 is an alpha-beta protein with some loop regions characterized by the presence of intrinsically unordered segments, (ii) only one cysteine (Cys57) is enough exposed to solvent, located on a loop and surrounded by charged and hydrophobic residues, and can be the cysteine able to bind the selenium. Cysteine 303-311 selenium binding protein 1 Homo sapiens 33-41 21338716-6 2011 Our studies demonstrate that (i) SELENBP1 is an alpha-beta protein with some loop regions characterized by the presence of intrinsically unordered segments, (ii) only one cysteine (Cys57) is enough exposed to solvent, located on a loop and surrounded by charged and hydrophobic residues, and can be the cysteine able to bind the selenium. Selenium 329-337 selenium binding protein 1 Homo sapiens 33-41 21405957-15 2011 However, this effect is significantly dependent on the initial PWV in the aorta and on SBP changes during allopurinol therapy. Allopurinol 106-117 selenium binding protein 1 Homo sapiens 87-90 21404246-1 2011 A novel transcriptional regulator responding to glucose was designed with a substrate-binding protein (SBP) as a probe towards intracellular sensing system for glucose in mammalian cells. Glucose 48-55 selenium binding protein 1 Homo sapiens 76-101 21404246-1 2011 A novel transcriptional regulator responding to glucose was designed with a substrate-binding protein (SBP) as a probe towards intracellular sensing system for glucose in mammalian cells. Glucose 48-55 selenium binding protein 1 Homo sapiens 103-106 21404246-1 2011 A novel transcriptional regulator responding to glucose was designed with a substrate-binding protein (SBP) as a probe towards intracellular sensing system for glucose in mammalian cells. Glucose 160-167 selenium binding protein 1 Homo sapiens 76-101 21404246-1 2011 A novel transcriptional regulator responding to glucose was designed with a substrate-binding protein (SBP) as a probe towards intracellular sensing system for glucose in mammalian cells. Glucose 160-167 selenium binding protein 1 Homo sapiens 103-106 21404246-2 2011 A chimeric protein of an SBP for glucose (GBP) and a LacI-type regulator, LacI (SLCP(GL) ), was designed, constructed and characterized using Escherichia coli recombinant protein. Glucose 33-40 selenium binding protein 1 Homo sapiens 25-28 21297499-3 2011 RESULTS: SBP and DBP, and resting heart rate decreased by 13, 13, and 12%, respectively, on nebivolol, and by 11, 13, and 7%, respectively, on metoprolol (all, P<0.01). Nebivolol 92-101 selenium binding protein 1 Homo sapiens 9-12 21124333-6 2011 After 8 weeks, aliskiren treatments reduced systolic blood pressure (SBP) from 169.0+-20.1 to 153.7+-19.6 mmHg (P<0.001) and diastolic blood pressure (DBP) from 78.1+-12.0 to 73.0+-13.6 mmHg (P=0.048). aliskiren 15-24 selenium binding protein 1 Homo sapiens 69-72 20479668-10 2011 Premedication with gabapentin alone significantly attenuated the SBP and MAP; however, HR responses were more variable. Gabapentin 19-29 selenium binding protein 1 Homo sapiens 65-68 22372022-9 2011 After adjustment, inverse associations between RA and DBP/SBP for both genders were found. Radium 47-49 selenium binding protein 1 Homo sapiens 58-61 21252701-8 2011 Baseline 24-h SBP values were 136.2 +- 11.6 mmHg (mean +- SD), 137.2 +- 12.5 mmHg and 136.8 +- 11.7 mmHg in the telmisartan monotherapy, nifedipine GITS monotherapy and combination therapy, respectively. Telmisartan 112-123 selenium binding protein 1 Homo sapiens 14-17 21252702-9 2011 By contrast, SBP increased after alcohol in hypertensive patients by 24 +- 6 mmHg (P < 0.001 vs. controls). Alcohols 33-40 selenium binding protein 1 Homo sapiens 13-16 21252703-3 2011 METHODS: In a community-based population of 1014 healthy participants, SBP-C and PP-C were estimated using carotid tonometry, and 24-h systolic (SBP-24 h) and pulse pressure (PP-24 h) were obtained from 24-h ambulatory blood pressure monitoring. Carbon 75-76 selenium binding protein 1 Homo sapiens 71-74 20945994-4 2011 The efficacy of manidipine and amlodipine was statistically equivalent: effect size for DBP = -0.08 (p = 0.22) and SBP = -0.01 (p = 0.83). manidipine 16-26 selenium binding protein 1 Homo sapiens 115-118 21045724-9 2011 Twenty-four-hour SBP at altitude was lower with carvedilol (116.4 +- 2.1 mmHg) than with placebo (125.8 +- 2.2 mmHg; P < 0.05) and intermediate with nebivolol (120.7 +- 2.1 mmHg; NS vs. others). Carvedilol 48-58 selenium binding protein 1 Homo sapiens 17-20 21045731-5 2011 RESULTS: With sequential models to control for multiple possible confounders (dietary, other), linear regression analyses showed that dietary cholesterol was directly related to SBP for all participants and for nonhypertensive individuals, but not to DBP. Cholesterol 142-153 selenium binding protein 1 Homo sapiens 178-181 21045731-6 2011 With adjustment for 12 variables, estimated SBP differences with 2SD for higher cholesterol intake (131.0 mg/1000 kcal) were 0.9 mmHg (P < 0.05) for all participants and 1.1 mmHg (P < 0.01) for nonhypertensive individuals, findings attenuated with addition of height and weight to the model. Cholesterol 80-91 selenium binding protein 1 Homo sapiens 44-47 21045731-7 2011 CONCLUSION: INTERMAP found a low-order, positive relationship of dietary cholesterol intake to SBP with control for multiple possible confounders. Cholesterol 73-84 selenium binding protein 1 Homo sapiens 95-98 21980964-3 2011 RESULTS: The blood pressure (BP) control with lisinopril was reduced by concomitantly administered diclofenac sodium in non-diabetic (SBP: p=0.00002; DBP: p=0.000008) and diabetic (SBP: p=0.002; DBP: p=0.001) patients when compared with the patients receiving lisinopril alone. Lisinopril 46-56 selenium binding protein 1 Homo sapiens 134-137 21980964-3 2011 RESULTS: The blood pressure (BP) control with lisinopril was reduced by concomitantly administered diclofenac sodium in non-diabetic (SBP: p=0.00002; DBP: p=0.000008) and diabetic (SBP: p=0.002; DBP: p=0.001) patients when compared with the patients receiving lisinopril alone. Lisinopril 46-56 selenium binding protein 1 Homo sapiens 181-184 21980964-3 2011 RESULTS: The blood pressure (BP) control with lisinopril was reduced by concomitantly administered diclofenac sodium in non-diabetic (SBP: p=0.00002; DBP: p=0.000008) and diabetic (SBP: p=0.002; DBP: p=0.001) patients when compared with the patients receiving lisinopril alone. Diclofenac 99-116 selenium binding protein 1 Homo sapiens 134-137 21980964-3 2011 RESULTS: The blood pressure (BP) control with lisinopril was reduced by concomitantly administered diclofenac sodium in non-diabetic (SBP: p=0.00002; DBP: p=0.000008) and diabetic (SBP: p=0.002; DBP: p=0.001) patients when compared with the patients receiving lisinopril alone. Diclofenac 99-116 selenium binding protein 1 Homo sapiens 181-184 22247724-9 2011 IOP and SBP were significantly higher in the atracurium compared with the cisatracurium group after 2 (p < 0.001 and 0.002, respectively), 5 (p < 0.001 and 0.012, respectively), and 10 (p = 0.02 and 0.048, respectively) minutes after intubation. Atracurium 45-55 selenium binding protein 1 Homo sapiens 8-11 21490816-7 2011 RESULTS: The SBP and DBP were significantly decreased after the propofol infusion in both group, but there were no significant differences between the two groups. Propofol 64-72 selenium binding protein 1 Homo sapiens 13-16 21265582-12 2011 At visit 2, 23% of patients were uptitrated to perindopril 8 mg/day, which resulted in an additional mean 10.1/5.3 mmHg BP reduction; this reduction was even greater (15.1/5.7 mmHg) among a separate group of severely hypertensive patients (i.e. SBP >170 mmHg or DBP >109 mmHg at baseline). Perindopril 47-58 selenium binding protein 1 Homo sapiens 245-248 21679007-10 2011 After 12 weeks" treatment with carvedilol, systolic/diastolic blood pressure (SBP/DBP) was reduced from 168.2 +- 18.6/95.7 +- 11.3 mmHg at baseline to 144.3 +- 17.3/83.4 +- 10.8 mmHg. Carvedilol 31-41 selenium binding protein 1 Homo sapiens 78-81 21079937-10 2011 During ritodrine -infusion, central SBP increased by 11% versus placebo (p = 0.012) and peripheral SBP by 10% (p = 0.004). Ritodrine 7-16 selenium binding protein 1 Homo sapiens 36-39 21079937-10 2011 During ritodrine -infusion, central SBP increased by 11% versus placebo (p = 0.012) and peripheral SBP by 10% (p = 0.004). Ritodrine 7-16 selenium binding protein 1 Homo sapiens 99-102 21915165-3 2011 MATERIALS AND METHODS: The Observational Study on Cognitive function And SBP Reduction (OSCAR) was an open-label, multinational trial designed to evaluate the impact of eprosartan-based antihypertensive therapy on cognitive function in patients with essential hypertension. eprosartan 169-179 selenium binding protein 1 Homo sapiens 73-76 22389857-5 2011 Although oral administration of tea polyphenols alone significantly decreased SBP in SHR at 2 and 4 hr, combined administration with Ameal failed to decrease SBP at the same time points. Polyphenols 36-47 selenium binding protein 1 Homo sapiens 78-81 25214999-9 2011 DC was associated with age (r=-0.459, P<0.001), SBP (r=-0.527, P<0.001), and serum calcium (r=-0.273, P=0.011). Deoxycytidine 0-2 selenium binding protein 1 Homo sapiens 51-54 21189915-10 2010 Patients receiving nebivolol and (S)-atenolol showed a significant fall (P < 0001) in systolic (SBP), diastolic blood pressure (DBP), and heart rate at the end of first, second, and third month when compared to baseline. Nebivolol 19-28 selenium binding protein 1 Homo sapiens 99-102 21194474-5 2010 Based on silver staining, and Western analysis, SBP delivered an outstanding specificity and purity of the condensin complex. Silver 9-15 selenium binding protein 1 Homo sapiens 48-51 21189915-10 2010 Patients receiving nebivolol and (S)-atenolol showed a significant fall (P < 0001) in systolic (SBP), diastolic blood pressure (DBP), and heart rate at the end of first, second, and third month when compared to baseline. Atenolol 33-45 selenium binding protein 1 Homo sapiens 99-102 20814869-7 2010 SBP stimulated GroEL ATP hydrolysis rate in a manner similar to that of alpha-lactalbumin. Adenosine Triphosphate 21-24 selenium binding protein 1 Homo sapiens 0-3 21147655-12 2010 CONCLUSION: A comparative analysis of diary records (omega-3 fatty acids & PANAS) and cardiovascular responses (Sphygmochron) showed that a person who is professionally and socially active in middle age can actively reduce her SBP/DBP with omega-3 fatty acids intervention. sphygmochron 116-128 selenium binding protein 1 Homo sapiens 231-234 21147655-12 2010 CONCLUSION: A comparative analysis of diary records (omega-3 fatty acids & PANAS) and cardiovascular responses (Sphygmochron) showed that a person who is professionally and socially active in middle age can actively reduce her SBP/DBP with omega-3 fatty acids intervention. Fatty Acids, Omega-3 53-72 selenium binding protein 1 Homo sapiens 231-234 21147655-12 2010 CONCLUSION: A comparative analysis of diary records (omega-3 fatty acids & PANAS) and cardiovascular responses (Sphygmochron) showed that a person who is professionally and socially active in middle age can actively reduce her SBP/DBP with omega-3 fatty acids intervention. Fatty Acids, Omega-3 244-263 selenium binding protein 1 Homo sapiens 231-234 20498606-7 2010 The SBP value at the 30th min was significantly higher in the LAD group than in the general anaesthesia group. lad 62-65 selenium binding protein 1 Homo sapiens 4-7 20814848-5 2010 Both aliskiren and losartan induced a significant and similar SBP/DBP reduction (-15.6/10.7 mmHg and -15.5/10.5 mmHg, p<0.001 vs. baseline, respectively). aliskiren 5-14 selenium binding protein 1 Homo sapiens 62-65 20814848-5 2010 Both aliskiren and losartan induced a significant and similar SBP/DBP reduction (-15.6/10.7 mmHg and -15.5/10.5 mmHg, p<0.001 vs. baseline, respectively). Losartan 19-27 selenium binding protein 1 Homo sapiens 62-65 20577121-2 2010 This systematic review and meta-analysis was performed to clarify the effects of soy isoflavone extract supplements on systolic and diastolic blood pressure (SBP and DBP) in adult humans. Isoflavones 85-95 selenium binding protein 1 Homo sapiens 158-161 20025693-3 2010 The objective of this study was to estimate the effects on systolic (SBP) and diastolic blood pressure (DBP) of orlistat and sibutramine. Orlistat 112-120 selenium binding protein 1 Homo sapiens 69-72 20025693-15 2010 For sibutramine, higher on-treatment elevations in SBP (1.6; -1.3, 4.5 vs. 0.1; -1.8, 2.0) and DBP (2.4; 0.6, 4.1 vs. 1.4; 0.3, 2.5) were seen in patients with vs. without diabetes. sibutramine 4-15 selenium binding protein 1 Homo sapiens 51-54 20025693-16 2010 In head-to-head trials, the overall differences between sibutramine and orlistat were small and non-significant for both SBP (1.0; -2.3, 4.3) and DBP (-0.2; -2.9, 2.5). sibutramine 56-67 selenium binding protein 1 Homo sapiens 121-124 20025693-16 2010 In head-to-head trials, the overall differences between sibutramine and orlistat were small and non-significant for both SBP (1.0; -2.3, 4.3) and DBP (-0.2; -2.9, 2.5). Orlistat 72-80 selenium binding protein 1 Homo sapiens 121-124 20729726-8 2010 CONCLUSION: The TRANSTEK blood pressure monitor TMB-986 passed all the phases of the International Protocol both for SBP and DBP and is recommended for home use. 3,3',5,5'-tetramethylbenzidine 48-51 selenium binding protein 1 Homo sapiens 117-120 20576784-5 2010 Patients that re-detached after initial PPV/SBP, PPV or SBP required silicone oil injection in 83%, 60% and 22% of the cases and had final best-corrected visual acuity better than or equal to 20/50 in 21%, 33% and 45% of the cases, respectively. Silicone Oils 69-81 selenium binding protein 1 Homo sapiens 56-59 20576784-7 2010 CONCLUSION: Patients with primary RRD that re-detach after initial treatment with SBP require fewer number of secondary operations and silicone oil injections, show a trend for better visual outcomes and are less likely to develop dense cataract or to require PPL compared to patients that re-detach after initial PPV or PPV/SBP. Silicone Oils 135-147 selenium binding protein 1 Homo sapiens 82-85 20577121-7 2010 Daily ingestion of 25-375 mg soy isoflavones (aglycone equivalents) for 2-24 weeks significantly decreased SBP by 1.92 mmHg (95% confidence interval -3.45 to -0.39; P = 0.01) compared with placebo (heterogeneity P = 0.39, fixed effect model) in adults with normal blood pressure and prehypertension. Isoflavones 33-44 selenium binding protein 1 Homo sapiens 107-110 20577121-7 2010 Daily ingestion of 25-375 mg soy isoflavones (aglycone equivalents) for 2-24 weeks significantly decreased SBP by 1.92 mmHg (95% confidence interval -3.45 to -0.39; P = 0.01) compared with placebo (heterogeneity P = 0.39, fixed effect model) in adults with normal blood pressure and prehypertension. CHEBI:166892 46-54 selenium binding protein 1 Homo sapiens 107-110 20577121-11 2010 CONCLUSION: Soy isoflavone extracts significantly decreased SBP but not DBP in adult humans, and no dose-response relationship was observed. Isoflavones 16-26 selenium binding protein 1 Homo sapiens 60-63 20577121-12 2010 Further studies are needed to address factors related to the observed effects of soy isoflavones on SBP and to verify the effect in hypertensive patients. Isoflavones 85-96 selenium binding protein 1 Homo sapiens 100-103 20016523-3 2010 The objective of this analysis was to compare the efficacy of candesartan and losartan with respect to reduction in systolic and diastolic BP (SBP and DBP). candesartan 62-73 selenium binding protein 1 Homo sapiens 143-146 20567855-11 2010 Cyclosporine (versus tacrolimus) was independently associated with greater SBP-Z and DBP-Z (p=0.001). Cyclosporine 0-12 selenium binding protein 1 Homo sapiens 75-78 20567855-11 2010 Cyclosporine (versus tacrolimus) was independently associated with greater SBP-Z and DBP-Z (p=0.001). Tacrolimus 21-31 selenium binding protein 1 Homo sapiens 75-78 20530237-6 2010 The opposing effects of SBP1 and GPX1 on each other were also observed when GPX1 was increased by supplementing the media of these tissue culture cells with selenium, and the effect of selenium on SBP1 was shown to be GPX1 dependent. Selenium 157-165 selenium binding protein 1 Homo sapiens 24-28 20530237-6 2010 The opposing effects of SBP1 and GPX1 on each other were also observed when GPX1 was increased by supplementing the media of these tissue culture cells with selenium, and the effect of selenium on SBP1 was shown to be GPX1 dependent. Selenium 185-193 selenium binding protein 1 Homo sapiens 197-201 20016523-3 2010 The objective of this analysis was to compare the efficacy of candesartan and losartan with respect to reduction in systolic and diastolic BP (SBP and DBP). Losartan 78-86 selenium binding protein 1 Homo sapiens 143-146 20556561-9 2010 However, the mean 24-hour ABPM SBP significantly decreased by 16.7 mmHg with eprosartan/HCTZ and 20.3 mmHg with losartan/HCTZ (P<0.001 vs. baseline). eprosartan 77-87 selenium binding protein 1 Homo sapiens 31-34 20693588-8 2010 Telmisartan produced a significant reduction in SBP (P<0.05). Telmisartan 0-11 selenium binding protein 1 Homo sapiens 48-51 20693588-9 2010 The addition of ramipril produced a further reduction in BP, the total reduction being 10.3 in SBP and 7.2 mmHg in DBP (P<0.001 for both). Ramipril 16-24 selenium binding protein 1 Homo sapiens 95-98 20726245-7 2010 The results demonstrated that the gender, age, occupation, fruit intake, temper or disposition, BMI, WC, WHR, SBP, TG, DM family history and the history of fetal macrosomia (female only) were significantly associated with the abnormal glucose regulation, but taking more fruits and the female sex were protective factors. Glucose 235-242 selenium binding protein 1 Homo sapiens 110-113 20556561-9 2010 However, the mean 24-hour ABPM SBP significantly decreased by 16.7 mmHg with eprosartan/HCTZ and 20.3 mmHg with losartan/HCTZ (P<0.001 vs. baseline). Hydrochlorothiazide 88-92 selenium binding protein 1 Homo sapiens 31-34 20556561-9 2010 However, the mean 24-hour ABPM SBP significantly decreased by 16.7 mmHg with eprosartan/HCTZ and 20.3 mmHg with losartan/HCTZ (P<0.001 vs. baseline). Losartan 112-120 selenium binding protein 1 Homo sapiens 31-34 20556561-9 2010 However, the mean 24-hour ABPM SBP significantly decreased by 16.7 mmHg with eprosartan/HCTZ and 20.3 mmHg with losartan/HCTZ (P<0.001 vs. baseline). Hydrochlorothiazide 121-125 selenium binding protein 1 Homo sapiens 31-34 20418302-7 2010 There was a linear relationship between the log-transformed dose of adenosine and the duration of a SBP(<60 mm Hg) (R(2) = 0.38). Adenosine 68-77 selenium binding protein 1 Homo sapiens 100-103 20602884-10 2010 Compared with the MDLS group, the occurrence time required for the maximum values of SBP after the start of intubation and the success of intubation were significantly delayed in the SOS group (P<0.05). sulfur monoxide 183-186 selenium binding protein 1 Homo sapiens 85-88 20486282-8 2010 X chromosome renin-binding protein gene markers rs1557501 and rs2269372 were associated with SBP response to low sodium in men (P=0.00004 and 0.0001, respectively). Sodium 113-119 selenium binding protein 1 Homo sapiens 93-96 20015524-4 2010 Glucose ingestion significantly increased low-frequency (LF(SBP)), low-frequency HRV (LF(RRI)), and the ratio of low- to high-frequency components of HRV (LF(RRI)/HF(RRI)), and decreased the high-frequency power (HF(RRI)) (P < .05). Glucose 0-7 selenium binding protein 1 Homo sapiens 60-63 20173652-8 2010 In contrast to the pronounced pressure response to high salt, a low-salt diet lowered the BP of salt-sensitive individuals as compared with salt-resistant individuals at daytime (SBP 107.6 +/- 1.2 vs. 114.8 +/- 1.6 mmHg, P = 0.002 in adults and SBP/DBP 103.1 +/- 1.6/68.6 +/- 1.5 vs. 111.2 +/- 1.3/74.5 +/- 1.1 mmHg, P = 0.005 in children), yet left night-time BP unchanged. Salts 68-72 selenium binding protein 1 Homo sapiens 179-182 20173652-8 2010 In contrast to the pronounced pressure response to high salt, a low-salt diet lowered the BP of salt-sensitive individuals as compared with salt-resistant individuals at daytime (SBP 107.6 +/- 1.2 vs. 114.8 +/- 1.6 mmHg, P = 0.002 in adults and SBP/DBP 103.1 +/- 1.6/68.6 +/- 1.5 vs. 111.2 +/- 1.3/74.5 +/- 1.1 mmHg, P = 0.005 in children), yet left night-time BP unchanged. Salts 68-72 selenium binding protein 1 Homo sapiens 245-248 20087217-8 2010 The mean differences between the device and mercury readings were -0.02 +/- 3.7 and -2.2 +/- 3.9 mmHg for SBP and DBP, respectively, for the Omron BP10 device; 1.5 +/- 5.7 and -0.6 +/- 3.8 mmHg for the Omron HBP T105 device; and -0.6 +/- 1.7 and -0.4 +/- 1.5 mmHg for the Pic Indolor Professional device. Mercury 44-51 selenium binding protein 1 Homo sapiens 106-109 20173652-8 2010 In contrast to the pronounced pressure response to high salt, a low-salt diet lowered the BP of salt-sensitive individuals as compared with salt-resistant individuals at daytime (SBP 107.6 +/- 1.2 vs. 114.8 +/- 1.6 mmHg, P = 0.002 in adults and SBP/DBP 103.1 +/- 1.6/68.6 +/- 1.5 vs. 111.2 +/- 1.3/74.5 +/- 1.1 mmHg, P = 0.005 in children), yet left night-time BP unchanged. Salts 68-72 selenium binding protein 1 Homo sapiens 179-182 20173652-8 2010 In contrast to the pronounced pressure response to high salt, a low-salt diet lowered the BP of salt-sensitive individuals as compared with salt-resistant individuals at daytime (SBP 107.6 +/- 1.2 vs. 114.8 +/- 1.6 mmHg, P = 0.002 in adults and SBP/DBP 103.1 +/- 1.6/68.6 +/- 1.5 vs. 111.2 +/- 1.3/74.5 +/- 1.1 mmHg, P = 0.005 in children), yet left night-time BP unchanged. Salts 68-72 selenium binding protein 1 Homo sapiens 245-248 20173652-8 2010 In contrast to the pronounced pressure response to high salt, a low-salt diet lowered the BP of salt-sensitive individuals as compared with salt-resistant individuals at daytime (SBP 107.6 +/- 1.2 vs. 114.8 +/- 1.6 mmHg, P = 0.002 in adults and SBP/DBP 103.1 +/- 1.6/68.6 +/- 1.5 vs. 111.2 +/- 1.3/74.5 +/- 1.1 mmHg, P = 0.005 in children), yet left night-time BP unchanged. Salts 68-72 selenium binding protein 1 Homo sapiens 179-182 20173652-8 2010 In contrast to the pronounced pressure response to high salt, a low-salt diet lowered the BP of salt-sensitive individuals as compared with salt-resistant individuals at daytime (SBP 107.6 +/- 1.2 vs. 114.8 +/- 1.6 mmHg, P = 0.002 in adults and SBP/DBP 103.1 +/- 1.6/68.6 +/- 1.5 vs. 111.2 +/- 1.3/74.5 +/- 1.1 mmHg, P = 0.005 in children), yet left night-time BP unchanged. Salts 68-72 selenium binding protein 1 Homo sapiens 245-248 20332323-2 2010 Because selenium-binding protein 1 (SELENBP1, SBP1, hSP56) has been shown to bind selenium covalently and selenium deficiency has been associated with esophageal adenocarcinoma (EAC), we examined its role in EAC development and its potential effect on chemosensitivity in the presence of selenium. Selenium 8-16 selenium binding protein 1 Homo sapiens 36-44 20332323-2 2010 Because selenium-binding protein 1 (SELENBP1, SBP1, hSP56) has been shown to bind selenium covalently and selenium deficiency has been associated with esophageal adenocarcinoma (EAC), we examined its role in EAC development and its potential effect on chemosensitivity in the presence of selenium. Selenium 8-16 selenium binding protein 1 Homo sapiens 52-57 20332323-2 2010 Because selenium-binding protein 1 (SELENBP1, SBP1, hSP56) has been shown to bind selenium covalently and selenium deficiency has been associated with esophageal adenocarcinoma (EAC), we examined its role in EAC development and its potential effect on chemosensitivity in the presence of selenium. Selenium 82-90 selenium binding protein 1 Homo sapiens 8-34 20332323-2 2010 Because selenium-binding protein 1 (SELENBP1, SBP1, hSP56) has been shown to bind selenium covalently and selenium deficiency has been associated with esophageal adenocarcinoma (EAC), we examined its role in EAC development and its potential effect on chemosensitivity in the presence of selenium. Selenium 82-90 selenium binding protein 1 Homo sapiens 36-44 20332323-2 2010 Because selenium-binding protein 1 (SELENBP1, SBP1, hSP56) has been shown to bind selenium covalently and selenium deficiency has been associated with esophageal adenocarcinoma (EAC), we examined its role in EAC development and its potential effect on chemosensitivity in the presence of selenium. Selenium 82-90 selenium binding protein 1 Homo sapiens 52-57 20332323-2 2010 Because selenium-binding protein 1 (SELENBP1, SBP1, hSP56) has been shown to bind selenium covalently and selenium deficiency has been associated with esophageal adenocarcinoma (EAC), we examined its role in EAC development and its potential effect on chemosensitivity in the presence of selenium. Selenium 82-90 selenium binding protein 1 Homo sapiens 8-34 20332323-2 2010 Because selenium-binding protein 1 (SELENBP1, SBP1, hSP56) has been shown to bind selenium covalently and selenium deficiency has been associated with esophageal adenocarcinoma (EAC), we examined its role in EAC development and its potential effect on chemosensitivity in the presence of selenium. Selenium 82-90 selenium binding protein 1 Homo sapiens 36-44 20332323-2 2010 Because selenium-binding protein 1 (SELENBP1, SBP1, hSP56) has been shown to bind selenium covalently and selenium deficiency has been associated with esophageal adenocarcinoma (EAC), we examined its role in EAC development and its potential effect on chemosensitivity in the presence of selenium. Selenium 82-90 selenium binding protein 1 Homo sapiens 52-57 20332323-3 2010 EXPERIMENTAL DESIGN: SELENBP1 expression level and copy number variation were determined by oligonucleotide microarrays, real-time reverse transcription-PCR, tissue microarrays, immunoblotting, and single-nucleotide polymorphism arrays. Oligonucleotides 92-107 selenium binding protein 1 Homo sapiens 21-29 20332323-5 2010 WST-1 cell proliferation assays, senescence-associated beta-galactosidase staining, immunoblotting, and flow cytometry were done to evaluate the biological significance of SELENBP1 overexpression in selenium-supplemented EAC cells. Selenium 199-207 selenium binding protein 1 Homo sapiens 172-180 20332323-8 2010 Stable overexpression of SELENBP1 in methylseleninic acid-supplemented Flo-1 cells resulted in enhanced apoptosis, increased cellular senescence, and enhanced cisplatin cytotoxicity. methylselenic acid 37-57 selenium binding protein 1 Homo sapiens 25-33 20332323-8 2010 Stable overexpression of SELENBP1 in methylseleninic acid-supplemented Flo-1 cells resulted in enhanced apoptosis, increased cellular senescence, and enhanced cisplatin cytotoxicity. Cisplatin 159-168 selenium binding protein 1 Homo sapiens 25-33 20332323-10 2010 CONCLUSIONS: SELENBP1 expression may be an important predictor of response to chemoprevention or chemosensitization with certain forms of selenium in esophageal tissues. Selenium 138-146 selenium binding protein 1 Homo sapiens 13-21 21090536-7 2010 Similarly, in elderly groups of both sexes, CPR was associated with significant absolute rise in SBP and DBP with diastolic percent rise more than systolic in males only. cpr 44-47 selenium binding protein 1 Homo sapiens 97-100 20461205-2 2010 To investigate the relationship between dietary factors or anthropometric indexes and hypertension risk, we examined the association of systolic and diastolic blood pressure (SBP and DBP) with sodium, calcium, and potassium intakes and anthropometric indexes in 19~49-year-olds using data from Korean National Health and Nutrition Examination Survey (KNHANES) III. Sodium 193-199 selenium binding protein 1 Homo sapiens 175-178 20461205-8 2010 Among 30~49-year-olds, calcium was inversely associated with both SBP and DBP (P = 0.012 and 0.010, respectively). Calcium 23-30 selenium binding protein 1 Homo sapiens 66-69 20234783-6 2010 However, the further mean reductions in BP versus monotherapy were significantly greater with the valsartan/amlodipine combination (SBP/DBP: -7.9 +/- 3.4/-6.5 +/- 2.6 mmHg for 24-hour, -8.0 +/- 3.4/-6.6 +/- 2.7 mmHg for daytime; -7.7 +/- 3.3/-6.4 +/- 2.7 mmHg for nighttime) than with the losartan/amlodipine combination (SBP/DBP: -5.5 +/- 2.8/-4.2 +/- 2.1 mmHg for 24-hour, -5.7 +/- 2.9/-4.4 +/- 2.2 mmHg for daytime; -4.8 +/- 2.8/-3.7 +/- 2.2 mmHg for nighttime; P < 0.01 vs valsartan/amlodipine). Valsartan 98-107 selenium binding protein 1 Homo sapiens 132-135 20234783-6 2010 However, the further mean reductions in BP versus monotherapy were significantly greater with the valsartan/amlodipine combination (SBP/DBP: -7.9 +/- 3.4/-6.5 +/- 2.6 mmHg for 24-hour, -8.0 +/- 3.4/-6.6 +/- 2.7 mmHg for daytime; -7.7 +/- 3.3/-6.4 +/- 2.7 mmHg for nighttime) than with the losartan/amlodipine combination (SBP/DBP: -5.5 +/- 2.8/-4.2 +/- 2.1 mmHg for 24-hour, -5.7 +/- 2.9/-4.4 +/- 2.2 mmHg for daytime; -4.8 +/- 2.8/-3.7 +/- 2.2 mmHg for nighttime; P < 0.01 vs valsartan/amlodipine). Valsartan 98-107 selenium binding protein 1 Homo sapiens 322-325 20234783-6 2010 However, the further mean reductions in BP versus monotherapy were significantly greater with the valsartan/amlodipine combination (SBP/DBP: -7.9 +/- 3.4/-6.5 +/- 2.6 mmHg for 24-hour, -8.0 +/- 3.4/-6.6 +/- 2.7 mmHg for daytime; -7.7 +/- 3.3/-6.4 +/- 2.7 mmHg for nighttime) than with the losartan/amlodipine combination (SBP/DBP: -5.5 +/- 2.8/-4.2 +/- 2.1 mmHg for 24-hour, -5.7 +/- 2.9/-4.4 +/- 2.2 mmHg for daytime; -4.8 +/- 2.8/-3.7 +/- 2.2 mmHg for nighttime; P < 0.01 vs valsartan/amlodipine). Amlodipine 108-118 selenium binding protein 1 Homo sapiens 132-135 20234783-6 2010 However, the further mean reductions in BP versus monotherapy were significantly greater with the valsartan/amlodipine combination (SBP/DBP: -7.9 +/- 3.4/-6.5 +/- 2.6 mmHg for 24-hour, -8.0 +/- 3.4/-6.6 +/- 2.7 mmHg for daytime; -7.7 +/- 3.3/-6.4 +/- 2.7 mmHg for nighttime) than with the losartan/amlodipine combination (SBP/DBP: -5.5 +/- 2.8/-4.2 +/- 2.1 mmHg for 24-hour, -5.7 +/- 2.9/-4.4 +/- 2.2 mmHg for daytime; -4.8 +/- 2.8/-3.7 +/- 2.2 mmHg for nighttime; P < 0.01 vs valsartan/amlodipine). Amlodipine 108-118 selenium binding protein 1 Homo sapiens 322-325 20125035-8 2010 Six SNPs of the ACE2 gene were significantly associated with SBP, DBP, or MAP responses to low-sodium intervention. Sodium 95-101 selenium binding protein 1 Homo sapiens 61-64 20125035-10 2010 Haplotype analysis indicated the A-T-T haplotype of APLNR SNPs rs721608-rs2282623-rs746886 was associated with decreased DBP and MAP responses to low-sodium intervention (P = 0.001 and 0.003, respectively), whereas G-C-C was associated with increased SBP and MAP responses to high-sodium intervention (P = 0.004 and 0.01, respectively). Sodium 150-156 selenium binding protein 1 Homo sapiens 251-254 20125035-10 2010 Haplotype analysis indicated the A-T-T haplotype of APLNR SNPs rs721608-rs2282623-rs746886 was associated with decreased DBP and MAP responses to low-sodium intervention (P = 0.001 and 0.003, respectively), whereas G-C-C was associated with increased SBP and MAP responses to high-sodium intervention (P = 0.004 and 0.01, respectively). Sodium 281-287 selenium binding protein 1 Homo sapiens 251-254 20211301-6 2010 RESULTS: At peak dobutamine infusion, SBP amplification averaged 14.9 mm Hg, with a maximum difference of 43 mm Hg. Dobutamine 17-27 selenium binding protein 1 Homo sapiens 38-41 20029377-5 2010 RESULTS: The ingestion of fructose resulted in an increase in ambulatory BP (7+/-2 and 5+/-2 mm Hg for systolic (SBP) and diastolic BP (DBP), P<0.004 and P<0.007, respectively). Fructose 26-34 selenium binding protein 1 Homo sapiens 113-116 20029377-10 2010 Allopurinol lowered the serum uric acid level (P<0.0001) and prevented the increase in 24-h ambulatory DBP and daytime SBP and DBP. Allopurinol 0-11 selenium binding protein 1 Homo sapiens 122-125 20009767-9 2010 Results were also statistically significant when fixed-effects models were used (SBP: X , -13.8 mmHg; 95% BCI, -15.3 to -11.0 mmHg and DBP: X , -6.1 mmHg; 95% BCI, -16.5 to -3.2 mmHg). (E)-2-Benzylidene-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one 106-109 selenium binding protein 1 Homo sapiens 81-84 20860416-3 2010 Therapy with candesartan cilexetil 0.05, 0.20, and 0.40 mg/kg/day for 4 weeks was effective in the treatment of hypertension in children aged 1 to <6 years, inducing significant dose-dependent reductions from baseline in sitting SBP (SSBP) [primary endpoint] and sitting DBP (SDBP) in the double-blind phase of a randomized, parallel-group, multinational, dose-ranging clinical study. candesartan 13-24 selenium binding protein 1 Homo sapiens 232-235 19907342-10 2010 CONCLUSION: Acylated ghrelin was positively associated with SBP and left ventricular mass indices, even after correction for BMI. Ghrelin 21-28 selenium binding protein 1 Homo sapiens 60-63 24683248-15 2010 When only high-quality studies were included, after 4 weeks" treatment, the weighted mean difference (WMD) of SBP and DBP decrease (1 study) was -2.84 (95% CI, -6.42 to 0.74) with (S)-amlodipine and -1.71 (95% CI, -3.48 to 0.06) with racemic amlodipine. Amlodipine 180-194 selenium binding protein 1 Homo sapiens 110-113 19896693-4 2010 The anticancer action of selenium has been suggested to be mediated by selenium-binding protein 1 as selenium-binding protein 1 is decreased in several cancers. Selenium 25-33 selenium binding protein 1 Homo sapiens 71-97 19896693-4 2010 The anticancer action of selenium has been suggested to be mediated by selenium-binding protein 1 as selenium-binding protein 1 is decreased in several cancers. Selenium 25-33 selenium binding protein 1 Homo sapiens 101-127 20860416-3 2010 Therapy with candesartan cilexetil 0.05, 0.20, and 0.40 mg/kg/day for 4 weeks was effective in the treatment of hypertension in children aged 1 to <6 years, inducing significant dose-dependent reductions from baseline in sitting SBP (SSBP) [primary endpoint] and sitting DBP (SDBP) in the double-blind phase of a randomized, parallel-group, multinational, dose-ranging clinical study. Cyclohexyl propan-2-yl carbonate 25-34 selenium binding protein 1 Homo sapiens 232-235 20193514-12 2009 The reduction of SBP was positively correlated with the reduction of 24h-UNa (r = 0.572, P = 0.026), while the reduction of proteinuria correlated with both the reduction of SBP (r = 0.568, P = 0.027) and 24h-UNa (r = 0.525, P = 0.044). 24h-una 69-76 selenium binding protein 1 Homo sapiens 17-20 20626227-6 2010 SBP and DBP was significantly lower only during night hours in anthracycline patients 19-22 years old. Anthracyclines 63-76 selenium binding protein 1 Homo sapiens 0-3 20131116-11 2010 CONCLUSION: After application of nitroglycerin, sBP is reduced immediately in HTX with uncontrolled cyclosporine-induced hypertension. Nitroglycerin 33-46 selenium binding protein 1 Homo sapiens 48-51 20131116-11 2010 CONCLUSION: After application of nitroglycerin, sBP is reduced immediately in HTX with uncontrolled cyclosporine-induced hypertension. Cyclosporine 100-112 selenium binding protein 1 Homo sapiens 48-51 19851298-8 2010 Compared to placebo, oral L-citrulline treatment decreased (P < 0.05) brachial SBP (-6 +/- 11 mm Hg), aortic SBP (-4 +/- 10 mm Hg), and aortic PP (-3 +/- 6 mm Hg) during CPT but not at rest. Citrulline 26-38 selenium binding protein 1 Homo sapiens 82-85 19851298-8 2010 Compared to placebo, oral L-citrulline treatment decreased (P < 0.05) brachial SBP (-6 +/- 11 mm Hg), aortic SBP (-4 +/- 10 mm Hg), and aortic PP (-3 +/- 6 mm Hg) during CPT but not at rest. Citrulline 26-38 selenium binding protein 1 Homo sapiens 112-115 19851298-9 2010 There was an inverse correlation (r = -0.40, P < 0.05) between changes in aortic SBP and Tr during CPT after L-citrulline supplementation. Citrulline 112-124 selenium binding protein 1 Homo sapiens 84-87 19851298-10 2010 CONCLUSIONS: We conclude that oral L-citrulline supplementation attenuates the brachial SBP, aortic SBP, and aortic PP responses to CPT in young normotensive men. Citrulline 35-47 selenium binding protein 1 Homo sapiens 88-91 19851298-10 2010 CONCLUSIONS: We conclude that oral L-citrulline supplementation attenuates the brachial SBP, aortic SBP, and aortic PP responses to CPT in young normotensive men. Citrulline 35-47 selenium binding protein 1 Homo sapiens 100-103 20370474-6 2010 With ASA on awakening, ambulatory BP was unchanged in men and slightly but significantly elevated in women (1.7/1.4 mmHg in the 48 h SBP/DBP means, respectively; p < 0.023). Aspirin 5-8 selenium binding protein 1 Homo sapiens 133-136 20370474-7 2010 BP was significantly reduced after aspirin at bedtime and to a larger extent in women (-8.0/-5.6 mmHg in SBP/DBP) than men (5.5/3.4 mmHg, respectively; p < 0.009 between men and women). Aspirin 35-42 selenium binding protein 1 Homo sapiens 105-108 20131116-6 2010 RESULTS: After injection of 50 microg and 100 microg nitroglycerin, BP significantly decreased both in HTX (systolic (s) BP p = 0.0001; diastolic (d) BP p = 0.0001) and in controls (sBP p = 0.006; dBP p = 0.05). Nitroglycerin 53-66 selenium binding protein 1 Homo sapiens 182-185 20131116-8 2010 Following analysis of the data in relation to its individual baseline, a significantly higher reduction of the BP induced by 100 microg nitroglycerin was observed in the HTX group compared to the HT group (p = 0.02 for sBP and p = 0.03 for dBP). Nitroglycerin 136-149 selenium binding protein 1 Homo sapiens 219-222 20131116-10 2010 The reduction in sBP was correlated to cyclosporine A levels (p = 0.04 after 50microg nitroglycerin; p = 0.05 after 100 microg nitroglycerin). Cyclosporine 39-53 selenium binding protein 1 Homo sapiens 17-20 20131116-10 2010 The reduction in sBP was correlated to cyclosporine A levels (p = 0.04 after 50microg nitroglycerin; p = 0.05 after 100 microg nitroglycerin). Nitroglycerin 86-99 selenium binding protein 1 Homo sapiens 17-20 20131116-10 2010 The reduction in sBP was correlated to cyclosporine A levels (p = 0.04 after 50microg nitroglycerin; p = 0.05 after 100 microg nitroglycerin). Nitroglycerin 127-140 selenium binding protein 1 Homo sapiens 17-20 20193514-12 2009 The reduction of SBP was positively correlated with the reduction of 24h-UNa (r = 0.572, P = 0.026), while the reduction of proteinuria correlated with both the reduction of SBP (r = 0.568, P = 0.027) and 24h-UNa (r = 0.525, P = 0.044). 24h-una 205-212 selenium binding protein 1 Homo sapiens 17-20 19824652-1 2009 Photochemical properties of alpha-cleavage of the C-S bond in excited states of p-biphenyl thioacetate and p-biphenyl thiobenzoate (Me-SBP and Ph-SBP) in solution are investigated using steady-state and laser flash photolyses in comparison with those of S-phenyl thiobenzoate, where the photo-Fries rearrangement was reported to be absent. Carbon 50-51 selenium binding protein 1 Homo sapiens 135-138 19824652-1 2009 Photochemical properties of alpha-cleavage of the C-S bond in excited states of p-biphenyl thioacetate and p-biphenyl thiobenzoate (Me-SBP and Ph-SBP) in solution are investigated using steady-state and laser flash photolyses in comparison with those of S-phenyl thiobenzoate, where the photo-Fries rearrangement was reported to be absent. Carbon 50-51 selenium binding protein 1 Homo sapiens 146-149 19824652-1 2009 Photochemical properties of alpha-cleavage of the C-S bond in excited states of p-biphenyl thioacetate and p-biphenyl thiobenzoate (Me-SBP and Ph-SBP) in solution are investigated using steady-state and laser flash photolyses in comparison with those of S-phenyl thiobenzoate, where the photo-Fries rearrangement was reported to be absent. Sulfur 52-53 selenium binding protein 1 Homo sapiens 135-138 19824652-1 2009 Photochemical properties of alpha-cleavage of the C-S bond in excited states of p-biphenyl thioacetate and p-biphenyl thiobenzoate (Me-SBP and Ph-SBP) in solution are investigated using steady-state and laser flash photolyses in comparison with those of S-phenyl thiobenzoate, where the photo-Fries rearrangement was reported to be absent. Sulfur 52-53 selenium binding protein 1 Homo sapiens 146-149 19824652-1 2009 Photochemical properties of alpha-cleavage of the C-S bond in excited states of p-biphenyl thioacetate and p-biphenyl thiobenzoate (Me-SBP and Ph-SBP) in solution are investigated using steady-state and laser flash photolyses in comparison with those of S-phenyl thiobenzoate, where the photo-Fries rearrangement was reported to be absent. p-biphenyl thiobenzoate 107-130 selenium binding protein 1 Homo sapiens 135-138 19824652-1 2009 Photochemical properties of alpha-cleavage of the C-S bond in excited states of p-biphenyl thioacetate and p-biphenyl thiobenzoate (Me-SBP and Ph-SBP) in solution are investigated using steady-state and laser flash photolyses in comparison with those of S-phenyl thiobenzoate, where the photo-Fries rearrangement was reported to be absent. p-biphenyl thiobenzoate 107-130 selenium binding protein 1 Homo sapiens 146-149 19824652-4 2009 Quantum yields (Phi(rad)) of the BTR formation were determined to be 0.20 and 0.15 for Me-SBP and Ph-SBP, respectively. btr 33-36 selenium binding protein 1 Homo sapiens 90-93 19824652-4 2009 Quantum yields (Phi(rad)) of the BTR formation were determined to be 0.20 and 0.15 for Me-SBP and Ph-SBP, respectively. btr 33-36 selenium binding protein 1 Homo sapiens 101-104 19824652-5 2009 Triplet sensitization of Ph-SBP using xanthone (XT) as a sensitizer shows that the lowest triplet (T(1)) state of Ph-SBP is dissociative for the C-S bond with an efficiency of >or.56. xanthone 38-46 selenium binding protein 1 Homo sapiens 28-31 19824652-5 2009 Triplet sensitization of Ph-SBP using xanthone (XT) as a sensitizer shows that the lowest triplet (T(1)) state of Ph-SBP is dissociative for the C-S bond with an efficiency of >or.56. xanthone 38-46 selenium binding protein 1 Homo sapiens 117-120 19824652-5 2009 Triplet sensitization of Ph-SBP using xanthone (XT) as a sensitizer shows that the lowest triplet (T(1)) state of Ph-SBP is dissociative for the C-S bond with an efficiency of >or.56. xanthone 48-50 selenium binding protein 1 Homo sapiens 28-31 19824652-5 2009 Triplet sensitization of Ph-SBP using xanthone (XT) as a sensitizer shows that the lowest triplet (T(1)) state of Ph-SBP is dissociative for the C-S bond with an efficiency of >or.56. xanthone 48-50 selenium binding protein 1 Homo sapiens 117-120 19824652-5 2009 Triplet sensitization of Ph-SBP using xanthone (XT) as a sensitizer shows that the lowest triplet (T(1)) state of Ph-SBP is dissociative for the C-S bond with an efficiency of >or.56. Carbon 145-146 selenium binding protein 1 Homo sapiens 28-31 19824652-5 2009 Triplet sensitization of Ph-SBP using xanthone (XT) as a sensitizer shows that the lowest triplet (T(1)) state of Ph-SBP is dissociative for the C-S bond with an efficiency of >or.56. Carbon 145-146 selenium binding protein 1 Homo sapiens 117-120 19824652-5 2009 Triplet sensitization of Ph-SBP using xanthone (XT) as a sensitizer shows that the lowest triplet (T(1)) state of Ph-SBP is dissociative for the C-S bond with an efficiency of >or.56. Sulfur 28-29 selenium binding protein 1 Homo sapiens 117-120 19824652-6 2009 In contrast, triplet sensitization of Me-SBP using acetone as a sensitizer demonstrates the efficient formation of triplet Me-SBP, and the molar absorption coefficient of the triplet-triplet absorption was determined. Acetone 51-58 selenium binding protein 1 Homo sapiens 41-44 19824652-6 2009 In contrast, triplet sensitization of Me-SBP using acetone as a sensitizer demonstrates the efficient formation of triplet Me-SBP, and the molar absorption coefficient of the triplet-triplet absorption was determined. Acetone 51-58 selenium binding protein 1 Homo sapiens 126-129 19824652-8 2009 Upon 355 nm laser flash photolysis of the T(1) state of Me-SBP, the formation of BTR is confirmed in the transient absorption. btr 81-84 selenium binding protein 1 Homo sapiens 59-62 19824652-9 2009 This observation indicates the C-S bond cleavage in a highly excited triplet (T(n)) state of Me-SBP. Carbon 31-32 selenium binding protein 1 Homo sapiens 96-99 19824652-9 2009 This observation indicates the C-S bond cleavage in a highly excited triplet (T(n)) state of Me-SBP. Sulfur 33-34 selenium binding protein 1 Homo sapiens 96-99 19574959-4 2009 RESULTS: We identified a significant association between a rare ADD1 variant rs17833172 and SBP, DBP, and MAP responses to high sodium (P values <0.0001) and DBP response to low sodium (P value = 0.002). Sodium 128-134 selenium binding protein 1 Homo sapiens 92-95 19924303-4 2009 Treatment with 5"-Aza-2"-deoxycytidine leads to demethylation of the SBP1 promoter and to an increase of SBP1 promoter activity, rescues SBP1 mRNA and protein expression in human colon cancer cells. Decitabine 15-38 selenium binding protein 1 Homo sapiens 69-73 19924303-4 2009 Treatment with 5"-Aza-2"-deoxycytidine leads to demethylation of the SBP1 promoter and to an increase of SBP1 promoter activity, rescues SBP1 mRNA and protein expression in human colon cancer cells. Decitabine 15-38 selenium binding protein 1 Homo sapiens 105-109 19924303-4 2009 Treatment with 5"-Aza-2"-deoxycytidine leads to demethylation of the SBP1 promoter and to an increase of SBP1 promoter activity, rescues SBP1 mRNA and protein expression in human colon cancer cells. Decitabine 15-38 selenium binding protein 1 Homo sapiens 105-109 19559411-5 2009 Total subjects (56.6+/-16.5A-weighted decibels (dBA)) had transient elevations of 1.15 (95% CI=0.86-1.43)mmHg SBP and 1.16 (0.93-1.38)mmHg DBP at daytime, as well as 0.74 (0.21-1.26)mmHg SBP and 0.77 (0.34-1.20)mmHg DBP at nighttime, significantly associated with a 5-dBA increase in noise exposure. 1,2,5,6-dibenzanthracene 48-51 selenium binding protein 1 Homo sapiens 110-113 19574959-4 2009 RESULTS: We identified a significant association between a rare ADD1 variant rs17833172 and SBP, DBP, and MAP responses to high sodium (P values <0.0001) and DBP response to low sodium (P value = 0.002). Sodium 181-187 selenium binding protein 1 Homo sapiens 92-95 19657733-5 2009 The first study on 47 healthy volunteers showed that both SBP and DPB correlated significantly both with baPWV and SI. bapwv 105-110 selenium binding protein 1 Homo sapiens 58-61 19296952-7 2009 Both age and SBP were also positively associated with CAC score > or =400, but the odds ratio for CAC score > or =400 was greater for every 1 micromol/L increment in serum bilirubin concentration than for every 1-year increment in age and 1-mmHg increment in SBP. Bilirubin 178-187 selenium binding protein 1 Homo sapiens 13-16 19296952-7 2009 Both age and SBP were also positively associated with CAC score > or =400, but the odds ratio for CAC score > or =400 was greater for every 1 micromol/L increment in serum bilirubin concentration than for every 1-year increment in age and 1-mmHg increment in SBP. Bilirubin 178-187 selenium binding protein 1 Homo sapiens 265-268 19657733-6 2009 Multiple regression models of the baPWV and the waist-to-hip ratio (WHR) allowed SBP and DBP to be modeled with r = 0.838 and r = 0.673, respectively. bapwv 34-39 selenium binding protein 1 Homo sapiens 81-84 19557004-10 2009 In HT, the CA16 carriers showed significantly higher SBP and plasma insulin levels and a higher tendency of sTNFR2 than did those without this allele. ca16 11-15 selenium binding protein 1 Homo sapiens 53-56 19633567-7 2009 Baseline SBP predicted young adult BP, cholesterol, triglycerides and glucose whereas baseline DBP predicted young adult BP, BMI and glucose. Glucose 70-77 selenium binding protein 1 Homo sapiens 9-12 19158826-6 2009 Aliskiren 300 mg significantly lowered both SBP -3.0 (-4.0, -2.0) and DBP -1.7 (-2.3, -1.0) as compared to aliskiren 150 mg. Aliskiren has no effect on blood pressure variability. aliskiren 0-9 selenium binding protein 1 Homo sapiens 44-47 19407805-7 2009 A significant ambulatory BP reduction was, however, observed in the subjects who received aspirin at bedtime (decrease of 6/3 mm Hg in the 24-h mean of systolic (SBP)/diastolic BP (DBP), respectively; P < 0.001), without changes in heart rate (HR) from baseline. Aspirin 90-97 selenium binding protein 1 Homo sapiens 162-165 19407805-8 2009 BP was homogeneously controlled along the 24 h after bedtime aspirin administration (6/4 mm Hg reduction in activity mean of SBP/DBP; 6/3 mm Hg reduction in sleep-time mean, respectively). Aspirin 61-68 selenium binding protein 1 Homo sapiens 125-128 19767812-5 2009 Results showed that, following caffeine ingestion: (i) both systolic and diastolic blood pressure (SBP and DBP, respectively) increased significantly (p < 0.05) in the older women (SBP, 128.4 +/- 14.2 vs. 132.1 +/- 13.0 mm Hg (3%); DBP, 80.2 +/- 6.9 vs. 83.4 +/- 7.5 mm Hg (4%), whereas only DBP increased in the younger women (67.1 +/- 4.7 vs. 69.9 +/- 5.4 mm Hg (4.2%); p < 0.05); (ii) heart rate decreased significantly (Y, 59.2 +/- 8.7 to 53.9 +/- 10.6 beats.min-1 (p < 0.05); O, 61.9 +/- 9.2 to 59.2 +/- 8.4 beats.min-1 (p < 0.05)) in both groups; and (iii) self-reported feelings of tension and vigor increased and feelings of fatigue decreased (p < 0.05) in younger women, whereas depression decreased (p < or = 0.05) in older women. Caffeine 31-39 selenium binding protein 1 Homo sapiens 99-102 19767812-5 2009 Results showed that, following caffeine ingestion: (i) both systolic and diastolic blood pressure (SBP and DBP, respectively) increased significantly (p < 0.05) in the older women (SBP, 128.4 +/- 14.2 vs. 132.1 +/- 13.0 mm Hg (3%); DBP, 80.2 +/- 6.9 vs. 83.4 +/- 7.5 mm Hg (4%), whereas only DBP increased in the younger women (67.1 +/- 4.7 vs. 69.9 +/- 5.4 mm Hg (4.2%); p < 0.05); (ii) heart rate decreased significantly (Y, 59.2 +/- 8.7 to 53.9 +/- 10.6 beats.min-1 (p < 0.05); O, 61.9 +/- 9.2 to 59.2 +/- 8.4 beats.min-1 (p < 0.05)) in both groups; and (iii) self-reported feelings of tension and vigor increased and feelings of fatigue decreased (p < 0.05) in younger women, whereas depression decreased (p < or = 0.05) in older women. Caffeine 31-39 selenium binding protein 1 Homo sapiens 184-187 19487301-3 2009 RESULTS: Of the 4 single nucleotide polymorphisms (SNPs) on the sodium bicarbonate cotransporter gene (SLC4A5), rs8179526 had a statistically significant interaction with cytosine/thymine (C/T) genotype by sodium status on systolic BP (SBP; p=.0077). Cytosine 171-179 selenium binding protein 1 Homo sapiens 236-239 19487301-5 2009 Two significant guanine/adenine [G/A] genotype by physical activity interactions were found on rs6731545 for SBP and DBP (p=.0160 and p=.0492, respectively). Adenine 24-31 selenium binding protein 1 Homo sapiens 109-112 19487301-3 2009 RESULTS: Of the 4 single nucleotide polymorphisms (SNPs) on the sodium bicarbonate cotransporter gene (SLC4A5), rs8179526 had a statistically significant interaction with cytosine/thymine (C/T) genotype by sodium status on systolic BP (SBP; p=.0077). Sodium 64-70 selenium binding protein 1 Homo sapiens 236-239 19487301-5 2009 Two significant guanine/adenine [G/A] genotype by physical activity interactions were found on rs6731545 for SBP and DBP (p=.0160 and p=.0492, respectively). Guanine 16-23 selenium binding protein 1 Homo sapiens 109-112 19487301-6 2009 DISCUSSION: A gene x environmental interaction with rs8179526 has a protective effect on SBP in African-American women with high sodium intake. Sodium 129-135 selenium binding protein 1 Homo sapiens 89-92 19487301-7 2009 Participants with C/T genotype of rs8179526 who consumed greater than 2,300 mg of sodium had lower SBP than those who consumed less than recommended. Sodium 82-88 selenium binding protein 1 Homo sapiens 99-102 19487301-8 2009 Women with thymine/thymine (T/T) genotype of rs8179526 who consumed greater than 2,300 mg had lower SBP than those who consumed less. Thymine 11-18 selenium binding protein 1 Homo sapiens 100-103 19487301-8 2009 Women with thymine/thymine (T/T) genotype of rs8179526 who consumed greater than 2,300 mg had lower SBP than those who consumed less. Thymine 19-26 selenium binding protein 1 Homo sapiens 100-103 18931896-8 2009 If anything, the greatest RRR of the primary endpoint (32%) occurred in patients with the lowest SBP (<120 mmHg) in whom perindopril did not reduce SBP. Perindopril 124-135 selenium binding protein 1 Homo sapiens 97-100 30625832-6 2009 RESULTS: Induction with thiopental caused a reduction in SBP and BIS (P < 0.01) in both groups. Thiopental 24-34 selenium binding protein 1 Homo sapiens 57-60 30625832-7 2009 Following the tracheal intubation SBP and HR increased in both groups, the magnitude of which was lower in the remifentanil group. Remifentanil 111-123 selenium binding protein 1 Homo sapiens 34-37 19464613-10 2009 The SBP in Groups F2 and F4 reached 160 +/- 31 mmHg and 123 +/- 36 mmHg, respectively, after intubation, but no significant change in SBP was noted in Group D-F2. Fluorine 18-20 selenium binding protein 1 Homo sapiens 4-7 19462489-10 2009 Length change from late pregnancy to the age of 2 years was positively associated with SBP and DBP [0.97 (95% CI, 0.27, 1.66) mmHg and 0.82 (95% CI, 0.09, 1.55) mmHg per SDS length change, respectively]. sds 170-173 selenium binding protein 1 Homo sapiens 87-90 18306050-10 2009 We showed that there are gaps between the key stakeholders prioritizations about the ACGME definition of SBP and, more generally, the behaviors and roles identified by healthcare team stakeholders beyond the U.S. acgme 85-90 selenium binding protein 1 Homo sapiens 105-108 19392925-1 2009 OBJECTIVE: To compare the efficacy of valsartan in systolic (SBP) and diastolic blood pressure (DBP) reduction with other angiotensin II receptor blockers (ARBs) in essential hypertension. Valsartan 38-47 selenium binding protein 1 Homo sapiens 61-64 19392925-9 2009 There is evidence that valsartan 160 mg reduces SBP and DBP more than irbesartan 150 mg and reduced DBP more than candesartan 16 mg. No other statistically significant difference in efficacy is demonstrated. Valsartan 23-32 selenium binding protein 1 Homo sapiens 48-51 19828899-5 2009 RESULTS: SBP and DBP were significantly reduced by approximately 2 mm Hg following both D-F&V and F&V diets vs. the control (P < 0.05). d-f& 88-95 selenium binding protein 1 Homo sapiens 9-12 19516186-6 2009 Etoricoxib (vs. diclofenac) was also significantly associated with increased SBP (P < 0.0001), DPB (P < 0.0001 to P = 0.0015), and exceeding SBP PLoC (P < 0.0001 to P = 0.002). Etoricoxib 0-10 selenium binding protein 1 Homo sapiens 77-80 19516186-6 2009 Etoricoxib (vs. diclofenac) was also significantly associated with increased SBP (P < 0.0001), DPB (P < 0.0001 to P = 0.0015), and exceeding SBP PLoC (P < 0.0001 to P = 0.002). Etoricoxib 0-10 selenium binding protein 1 Homo sapiens 147-150 19516186-6 2009 Etoricoxib (vs. diclofenac) was also significantly associated with increased SBP (P < 0.0001), DPB (P < 0.0001 to P = 0.0015), and exceeding SBP PLoC (P < 0.0001 to P = 0.002). Diclofenac 16-26 selenium binding protein 1 Homo sapiens 77-80 19516186-6 2009 Etoricoxib (vs. diclofenac) was also significantly associated with increased SBP (P < 0.0001), DPB (P < 0.0001 to P = 0.0015), and exceeding SBP PLoC (P < 0.0001 to P = 0.002). Diclofenac 16-26 selenium binding protein 1 Homo sapiens 147-150 19828899-5 2009 RESULTS: SBP and DBP were significantly reduced by approximately 2 mm Hg following both D-F&V and F&V diets vs. the control (P < 0.05). f& 90-95 selenium binding protein 1 Homo sapiens 9-12 18989258-8 2008 Blood pressure reduction in the telmisartan group (DeltaSBP: -13.5 (95% CI, -17.0 to -10.0) mm Hg; DeltaDBP: -7.6 (95% CI, -9.8 to -5.3) mm Hg, each P < 0.001) was significantly (P < or = 0.01 for SBP and P < 0.01 for DBP) greater than in the ramipril group (DeltaSBP: -6.1 (95% CI, -6.2 to -2.0) mm Hg; DeltaDBP: -2.7 (95% CI, -5.0 to -0.5) mm Hg; P < 0.01 and P < 0.05, respectively). Telmisartan 32-43 selenium binding protein 1 Homo sapiens 56-59 19655820-4 2009 Trough sitting DBP and SBP were reduced to a significantly greater extent in nebivolol than in placebo recipients in trials in demographically heterogenous hypertensive patient groups, as well as in trials involving only Black patients and in patients continuing previous stable antihypertensive drug therapies. Nebivolol 77-86 selenium binding protein 1 Homo sapiens 23-26 19963769-5 2009 Blood pressures: sBP (2.8%), dBP(3.6%), and TPRI (5.3%) showed statistically significant increases after the water ingestion. Water 109-114 selenium binding protein 1 Homo sapiens 17-20 19020533-8 2009 Oral magnesium supplementation with MgCl(2) significantly reduces SBP and DBP in diabetic hypertensive adults with hypomagnesaemia. Magnesium 5-14 selenium binding protein 1 Homo sapiens 66-69 19020533-8 2009 Oral magnesium supplementation with MgCl(2) significantly reduces SBP and DBP in diabetic hypertensive adults with hypomagnesaemia. Magnesium Chloride 36-43 selenium binding protein 1 Homo sapiens 66-69 19329013-9 2009 MAIN RESULTS: All postintubation values of SBP, DBP, MAP, and HR were significantly lower in the lidocaine group than the control group (P < 0.01). Lidocaine 97-106 selenium binding protein 1 Homo sapiens 43-46 19118533-0 2009 Human selenium binding protein-1 (hSP56) interacts with VDU1 in a selenium-dependent manner. Selenium 6-14 selenium binding protein 1 Homo sapiens 34-39 19118533-2 2009 hSP56 also has been implicated in selenium-dependent cell growth inhibition. Selenium 34-42 selenium binding protein 1 Homo sapiens 0-5 19118533-7 2009 The full-length VDU1 specifically interacted with a selenium-replete form of hSP56. Selenium 52-60 selenium binding protein 1 Homo sapiens 77-82 19118533-8 2009 We also demonstrate stable incorporation of selenium into hSP56, in a mode distinct from conventional selenocysteine-containing selenoproteins. Selenium 44-52 selenium binding protein 1 Homo sapiens 58-63 19118533-9 2009 These findings suggest that hSP56 may play a role in ubiquitination/deubiquitination-mediated protein degradation pathways in a selenium-dependent manner. Selenium 128-136 selenium binding protein 1 Homo sapiens 28-33 21817273-2 2009 In this work, we have measured, by optical spectroscopic reflectometry in the visible-near-infrared region, the interaction between a sugar binding protein (SBP), covalently bound on the surface of a porous silicon (PSi) microcavity, and glucose, at different concentrations and temperatures. Glucose 238-245 selenium binding protein 1 Homo sapiens 134-155 21817273-2 2009 In this work, we have measured, by optical spectroscopic reflectometry in the visible-near-infrared region, the interaction between a sugar binding protein (SBP), covalently bound on the surface of a porous silicon (PSi) microcavity, and glucose, at different concentrations and temperatures. Glucose 238-245 selenium binding protein 1 Homo sapiens 157-160 19114657-2 2009 We conducted a genome-wide association study of systolic and diastolic blood pressure (SBP and DBP) in Amish subjects and found strong association signals with common variants in a serine/threonine kinase gene, STK39. Serine 181-187 selenium binding protein 1 Homo sapiens 87-90 19655819-1 2009 BACKGROUND: The combination of olmesartan medoxomil and hydrochlorothiazide (HCTZ) [olmesartan medoxomil/HCTZ] has previously been shown to produce significantly greater SBP/DBP reductions than monotherapy with either agent alone in a randomized, double-blind, factorial study in patients with stage 2 hypertension. olmesartan 31-41 selenium binding protein 1 Homo sapiens 170-173 19655819-1 2009 BACKGROUND: The combination of olmesartan medoxomil and hydrochlorothiazide (HCTZ) [olmesartan medoxomil/HCTZ] has previously been shown to produce significantly greater SBP/DBP reductions than monotherapy with either agent alone in a randomized, double-blind, factorial study in patients with stage 2 hypertension. medoxomil 42-51 selenium binding protein 1 Homo sapiens 170-173 19655819-1 2009 BACKGROUND: The combination of olmesartan medoxomil and hydrochlorothiazide (HCTZ) [olmesartan medoxomil/HCTZ] has previously been shown to produce significantly greater SBP/DBP reductions than monotherapy with either agent alone in a randomized, double-blind, factorial study in patients with stage 2 hypertension. Hydrochlorothiazide 56-75 selenium binding protein 1 Homo sapiens 170-173 19655819-1 2009 BACKGROUND: The combination of olmesartan medoxomil and hydrochlorothiazide (HCTZ) [olmesartan medoxomil/HCTZ] has previously been shown to produce significantly greater SBP/DBP reductions than monotherapy with either agent alone in a randomized, double-blind, factorial study in patients with stage 2 hypertension. Hydrochlorothiazide 77-81 selenium binding protein 1 Homo sapiens 170-173 19655819-1 2009 BACKGROUND: The combination of olmesartan medoxomil and hydrochlorothiazide (HCTZ) [olmesartan medoxomil/HCTZ] has previously been shown to produce significantly greater SBP/DBP reductions than monotherapy with either agent alone in a randomized, double-blind, factorial study in patients with stage 2 hypertension. olmesartan 84-94 selenium binding protein 1 Homo sapiens 170-173 19655819-1 2009 BACKGROUND: The combination of olmesartan medoxomil and hydrochlorothiazide (HCTZ) [olmesartan medoxomil/HCTZ] has previously been shown to produce significantly greater SBP/DBP reductions than monotherapy with either agent alone in a randomized, double-blind, factorial study in patients with stage 2 hypertension. medoxomil 95-104 selenium binding protein 1 Homo sapiens 170-173 19655819-1 2009 BACKGROUND: The combination of olmesartan medoxomil and hydrochlorothiazide (HCTZ) [olmesartan medoxomil/HCTZ] has previously been shown to produce significantly greater SBP/DBP reductions than monotherapy with either agent alone in a randomized, double-blind, factorial study in patients with stage 2 hypertension. Hydrochlorothiazide 105-109 selenium binding protein 1 Homo sapiens 170-173 19655819-9 2009 All combined SBP/DBP goals were achieved by a statistically significant proportion of patients (p < 0.05) in the olmesartan medoxomil/HCTZ 20/25, 40/12.5, and 40/25 treatment groups. olmesartan 116-126 selenium binding protein 1 Homo sapiens 13-16 20409942-10 2009 However, the prevalence of individuals meeting ATP III criteria for BP was highest in the third tertile of both SBP and DBP. atp iii 47-54 selenium binding protein 1 Homo sapiens 112-115 19090875-3 2008 Systolic (SBP)/diastolic (DBP) blood pressure declined 8.6/4.8-11.2/8.0 mm Hg with candesartan and 3.7/1.8 mm Hg with placebo (P<.01 compared to placebo for SBP and for the mid and high doses for DBP; placebo-corrected 4.9/3.0-7.5/6.2 mm Hg). candesartan 83-94 selenium binding protein 1 Homo sapiens 10-13 19080275-8 2008 RESULTS: Compared with the screening day, the falls in systolic, diastolic and mean arterial blood pressure (SBP, DBP, MAP) (all P < 0.05) were significantly attenuated after taking acarbose during breakfast, so were MAP (P < 0.05) during lunch, DBP (P < 0.05) and MAP (P < 0.05) during supper. Acarbose 185-193 selenium binding protein 1 Homo sapiens 109-112 18843743-18 2008 Aliskiren 300 mg significantly lowered both SBP and DBP as compared to aliskiren 150 mg (SBP:-2.97 (95% CI -3.99, -1.95) and DBP: -1.66 (95% CI -2.32, -1.0). aliskiren 0-9 selenium binding protein 1 Homo sapiens 44-47 18843743-18 2008 Aliskiren 300 mg significantly lowered both SBP and DBP as compared to aliskiren 150 mg (SBP:-2.97 (95% CI -3.99, -1.95) and DBP: -1.66 (95% CI -2.32, -1.0). aliskiren 0-9 selenium binding protein 1 Homo sapiens 89-92 18799950-8 2008 Overall, the work to sleep change in epinephrine excretion was positively associated with changes in both SBP (P<0.003) and DBP (P<0.001); however, there was an ethnic difference in the epinephrine-BP relationship. Epinephrine 37-48 selenium binding protein 1 Homo sapiens 106-109 18855259-9 2008 Office SBP decreased more and sooner in patients allocated to enalapril (p = 0.003). Enalapril 62-71 selenium binding protein 1 Homo sapiens 7-10 18681815-6 2008 RESULTS: Treatment with irbesartan/HCTZ was associated with significant mean reductions in BP (intent-to-treat population, n = 370; SBP/DBP: -22.9/-10.3 +/- 14.7/8.8 mm Hg). Irbesartan 24-34 selenium binding protein 1 Homo sapiens 132-135 18485132-5 2008 Ambulatory 24-h BP monitoring (ABPM) measurements in a subset of 100 patients showed greater daytime SBP reductions in the torasemide-PR group (128.4 +/- 9.9 mmHg vs. 133.5 +/- 10.4 mmHg, P < 0.05). Torsemide 123-133 selenium binding protein 1 Homo sapiens 101-104 19102867-5 2008 Multiple regression analysis showed that age, Hb, pulse rate, SBP, TC, gender, TG and creatinine were significantly related to BNP and age, creatinine, Hb, gender, TG, TC, SBP, pulse rate were significantly related to NT-proBNP. Creatinine 86-96 selenium binding protein 1 Homo sapiens 172-175 18681815-6 2008 RESULTS: Treatment with irbesartan/HCTZ was associated with significant mean reductions in BP (intent-to-treat population, n = 370; SBP/DBP: -22.9/-10.3 +/- 14.7/8.8 mm Hg). Hydrochlorothiazide 35-39 selenium binding protein 1 Homo sapiens 132-135 18712159-13 2008 From the other variables that may induce differences in blood pressure, a statistical effect was detected for glucose, Na/K, and Apo A1/ApoB ratios and physical activity on SBP, and for ApoA1, physical activity, BMI and total cholesterol on DBP. Glucose 110-117 selenium binding protein 1 Homo sapiens 173-176 18538022-14 2008 Mercury was positively correlated with SBP (r = 0.25; p < 0.0001) and PP (r = 0.33; p < 0.0001). Mercury 0-7 selenium binding protein 1 Homo sapiens 39-42 18538022-18 2008 SBP and PP increased with blood mercury concentrations while SDANN decreased with blood mercury concentrations. Mercury 32-39 selenium binding protein 1 Homo sapiens 0-3 18615394-7 2008 There were significant correlations between values for ghrelin levels after weight loss and SBP (r = -0.45, p = 0.02), DBP (r = -0.41, p < 0.05), and between Deltaghrelin levels and DeltaSBP (r = 0.52, p = 0.006), DeltaDBP (r = 0.53, p = 0.005). Ghrelin 55-62 selenium binding protein 1 Homo sapiens 92-95 18437146-9 2008 Use of telmisartan resulted in a significant reduction in clinic DBP (weighted mean difference 1.52, 95% confidence interval (CI) 0.85-2.19) and SBP (2.77, 1.90-3.63) when compared with losartan. Telmisartan 7-18 selenium binding protein 1 Homo sapiens 145-148 18437146-10 2008 There was also a significant reduction in 24-h mean ambulatory DBP (2.49, 0.56-4.42) and SBP (2.47, 0.40-4.55) with telmisartan as compared to losartan. Telmisartan 116-127 selenium binding protein 1 Homo sapiens 89-92 18437146-11 2008 There was also a significant increase in therapeutic response of DBP (relative risk (RR) 1.14, 1.04-1.23) and SBP response (1.10, 1.01-1.20) with telmisartan as compared to losartan. Telmisartan 146-157 selenium binding protein 1 Homo sapiens 110-113 18840010-20 2008 CONCLUSION: In this community-based clinical practice trial, up to 10 weeks" perindopril therapy, uptitrated to the maximal recommended dose as required for BP control, significantly reduced SBP/DBP in patients with mild-to-moderate hypertension and additional CV risk factors. Perindopril 77-88 selenium binding protein 1 Homo sapiens 191-194 18410888-10 2008 Reactance (representative of extracellular water) correlated with supine, sitting, and standing SBP (r = 0.55, 0.59, and 0.51, respectively; P < or = .008). Water 43-48 selenium binding protein 1 Homo sapiens 96-99 18840010-15 2008 Perindopril produced significant SBP/DBP reductions at 2 and 10 weeks (-15.8/-8.0 and -21.1/-11.0 mmHg, respectively). Perindopril 0-11 selenium binding protein 1 Homo sapiens 33-36 18356684-5 2008 SBP/DBP values were significantly reduced after 12 months with valsartan/amlodipine (from 150.4/93.5 to 126.37/7.4 mm Hg, P < 0.001) and atenolol/amlodipine (from 151.1/94.2 to 127.1/77.9 mm Hg, P < 0.001), with no difference between the 2 regimens. Valsartan 63-72 selenium binding protein 1 Homo sapiens 0-3 18356684-5 2008 SBP/DBP values were significantly reduced after 12 months with valsartan/amlodipine (from 150.4/93.5 to 126.37/7.4 mm Hg, P < 0.001) and atenolol/amlodipine (from 151.1/94.2 to 127.1/77.9 mm Hg, P < 0.001), with no difference between the 2 regimens. Amlodipine 73-83 selenium binding protein 1 Homo sapiens 0-3 18356684-5 2008 SBP/DBP values were significantly reduced after 12 months with valsartan/amlodipine (from 150.4/93.5 to 126.37/7.4 mm Hg, P < 0.001) and atenolol/amlodipine (from 151.1/94.2 to 127.1/77.9 mm Hg, P < 0.001), with no difference between the 2 regimens. Atenolol 140-148 selenium binding protein 1 Homo sapiens 0-3 18356684-5 2008 SBP/DBP values were significantly reduced after 12 months with valsartan/amlodipine (from 150.4/93.5 to 126.37/7.4 mm Hg, P < 0.001) and atenolol/amlodipine (from 151.1/94.2 to 127.1/77.9 mm Hg, P < 0.001), with no difference between the 2 regimens. Amlodipine 149-159 selenium binding protein 1 Homo sapiens 0-3 18831354-8 2008 In the PMS group, the basal HR was 90.61 +/- 8.46, SBP 122.5 +/- 11.52, DBP 83.53 +/- 8.26, EMG 5.79 +/-2.75, EDG 13.14 +/- 6.54, RR 19.13 +/- 3.76 and T was 93.43 -/+ 5.29. Promethium 7-10 selenium binding protein 1 Homo sapiens 51-54 18206598-11 2008 CONCLUSIONS: Eprosartan seems to be effective in reducing SBP, DBP, and pulse pressure in hypertensive subjects and to the same extent in both diabetic and non-diabetic patients. eprosartan 13-23 selenium binding protein 1 Homo sapiens 58-61 18752143-6 2008 RESULTS: L-NMMA induced a significant increase in SBP and DBP in both groups. omega-N-Methylarginine 9-15 selenium binding protein 1 Homo sapiens 50-53 18981627-5 2008 RESULTS: Valsartan/amlodipine combination produced a significantly greater decrease in SBP/DBP values (-22.3/16.7 mmHg, p<0.001 vs baseline) than valsartan (-15.2/11.7 mmHg, p<0.01 vs baseline) and amlodipine monotherapy (-16.1/12.6 mmHg, p<0.01 vs baseline). Valsartan 9-18 selenium binding protein 1 Homo sapiens 87-90 18981627-5 2008 RESULTS: Valsartan/amlodipine combination produced a significantly greater decrease in SBP/DBP values (-22.3/16.7 mmHg, p<0.001 vs baseline) than valsartan (-15.2/11.7 mmHg, p<0.01 vs baseline) and amlodipine monotherapy (-16.1/12.6 mmHg, p<0.01 vs baseline). Amlodipine 19-29 selenium binding protein 1 Homo sapiens 87-90 18188985-7 2007 The pre-treatment SBP, DD genotype, aldosterone levels entered the multi-linear regression model significantly and might affect the reduction of SBP. Aldosterone 36-47 selenium binding protein 1 Homo sapiens 145-148 19048102-6 2008 Streptavidin agarose column chromatography with the SBP tag successfully isolated the protein complexes in a native form with a high purity. Sepharose 13-20 selenium binding protein 1 Homo sapiens 52-55 18054613-12 2008 CONCLUSION: A reduction of BP by 15% (SBP < or =140 mm Hg, DBP < or =80 mm Hg) is necessary at acute stage in S-ICH. Benzo(a)pyrene 27-29 selenium binding protein 1 Homo sapiens 38-41 17910648-13 2007 Similarly, SBP and DBP trended higher and CHOL was significantly higher in patients receiving SRL vs. mycophenolate mofetil. Mycophenolic Acid 102-123 selenium binding protein 1 Homo sapiens 11-14 17485790-9 2007 Common causes of SBP mostly were Escherichia coli and Acinettobacter baumanii, which were sensitive to antibiotic treatment of Cefoperazone, Cefotaxime and Ciprofloxacin. Cefoperazone 127-139 selenium binding protein 1 Homo sapiens 17-20 17519432-9 2007 SBP change differed only between COC and DMPA groups (adjusted slopes: 1.3 vs. -1.7 mmHg/year, respectively; P = 0.01). Medroxyprogesterone Acetate 41-45 selenium binding protein 1 Homo sapiens 0-3 17635183-13 2007 Decline of mean daytime SBP in 24-h ambulatory blood pressure monitoring was more significant in Pro allele carriers (-21.0 +/- 2.55 mmHg vs. -5.2 +/- 2.27 mmHg in patients with Ser/Ser genotype, P = 0.001). Serine 178-181 selenium binding protein 1 Homo sapiens 24-27 17635183-13 2007 Decline of mean daytime SBP in 24-h ambulatory blood pressure monitoring was more significant in Pro allele carriers (-21.0 +/- 2.55 mmHg vs. -5.2 +/- 2.27 mmHg in patients with Ser/Ser genotype, P = 0.001). Serine 182-185 selenium binding protein 1 Homo sapiens 24-27 17849744-10 2007 In the 25-OHD <20 ng/ml group age, BMI, and SBP were significantly higher than in the 25-OHD 220 ng/ml group, while QUICKI (<0.35 is consistent with insulin resistance) was borderline low in the <20 ng/ml group. 25-ohd 7-13 selenium binding protein 1 Homo sapiens 47-50 17849744-14 2007 Vitamin D insufficiency was associated with increased age, BMI, and SBP, and decreased HDL-C. Vitamin D 0-9 selenium binding protein 1 Homo sapiens 68-71 17847932-5 2007 Rise of SBP(mtt) above 200 mmHg was considered abnormal reaction. monooxyethylene trimethylolpropane tristearate 12-15 selenium binding protein 1 Homo sapiens 8-11 17847932-6 2007 Simple linear regression analysis showed significant inverse relationship between SBP(mtt) and FMD (F = 20.2036, p < 0.001, R2 = 0.0956). monooxyethylene trimethylolpropane tristearate 86-89 selenium binding protein 1 Homo sapiens 82-85 17847932-9 2007 There was a significant inverse relationship between SBP(mtt) and FMD. monooxyethylene trimethylolpropane tristearate 57-60 selenium binding protein 1 Homo sapiens 53-56 17847932-10 2007 An impairment of FMD exists in normotensive subjects with abnormal SBP(mtt). monooxyethylene trimethylolpropane tristearate 71-74 selenium binding protein 1 Homo sapiens 67-70 17847932-11 2007 In hypertensives with abnormal SBP(mtt) an additional impairment of FMD exists when compared to hypertensives with normal SBP(mtt). monooxyethylene trimethylolpropane tristearate 35-38 selenium binding protein 1 Homo sapiens 31-34 17847932-11 2007 In hypertensives with abnormal SBP(mtt) an additional impairment of FMD exists when compared to hypertensives with normal SBP(mtt). monooxyethylene trimethylolpropane tristearate 126-129 selenium binding protein 1 Homo sapiens 31-34 17705541-10 2007 An analysis of the X-ray crystal structure of complex 6H22+.HPO42- revealed a strong resemblance to the active site of the phosphate binding protein (PBP) with similar structural analogies being drawn between the active site of the sulfate binding protein (SBP) and the corresponding hydrogensulfate anion complex. Phosphates 123-132 selenium binding protein 1 Homo sapiens 232-255 17705541-10 2007 An analysis of the X-ray crystal structure of complex 6H22+.HPO42- revealed a strong resemblance to the active site of the phosphate binding protein (PBP) with similar structural analogies being drawn between the active site of the sulfate binding protein (SBP) and the corresponding hydrogensulfate anion complex. Phosphates 123-132 selenium binding protein 1 Homo sapiens 257-260 17705541-10 2007 An analysis of the X-ray crystal structure of complex 6H22+.HPO42- revealed a strong resemblance to the active site of the phosphate binding protein (PBP) with similar structural analogies being drawn between the active site of the sulfate binding protein (SBP) and the corresponding hydrogensulfate anion complex. hydrogensulfate anion 284-305 selenium binding protein 1 Homo sapiens 232-255 17705541-10 2007 An analysis of the X-ray crystal structure of complex 6H22+.HPO42- revealed a strong resemblance to the active site of the phosphate binding protein (PBP) with similar structural analogies being drawn between the active site of the sulfate binding protein (SBP) and the corresponding hydrogensulfate anion complex. hydrogensulfate anion 284-305 selenium binding protein 1 Homo sapiens 257-260 17998769-6 2007 Morning SBP (P < 0.001) and DBP (P < 0.001) decreased significantly from 150.2 +/- 8.7 and 87.8 +/- 9.3 to 132.7 +/- 7.4 and 77.5 +/- 8.5 mmHg, respectively, after the addition of cilnidipine. cilnidipine 186-197 selenium binding protein 1 Homo sapiens 8-11 17985502-11 2007 In regression models of select socioeconomic, lifestyle risk and HTN care variables, significant predictors of lower SBP and DBP or BP control included: fewer antihypertensive medications, better compliance to HTN recommendations, younger age, female, higher education level, not using alcohol excessively, and private sector healthcare. Alcohols 286-293 selenium binding protein 1 Homo sapiens 117-120 17407587-11 2007 RESULTS: After 9 month the use of Irbesartan in monotherapy resulted in a significant reduction of blood pressure (SBP: -26.3 +/- 10.1 mmHg/DBP-13.0 +/- 6.6 mmHg, both p < 0.0001) in patients with the metabolic syndrome. Irbesartan 34-44 selenium binding protein 1 Homo sapiens 115-118 17407587-13 2007 Irbesartan combination therapy (12.5 mg HCTZ) in patients with the metabolic syndrome: blood pressure reduction (SBP: -27.5 +/- 10.1 mmHg/DBP: -14.1 +/- 6.6 mmHg, both p < 0.0001), improvement in HDL cholesterol (+4.0 +/- 6.8 mg/dl in men, +3.4 +/- 6.8 in women, both p < 0.0001), triglycerides (-34.1 +/- 52.6 mg/dl, p < 0.0001), fasting blood glucose (-10.0 +/- 24.7, p < 0.0001) and waist circumference (-3.2 +/- 12.7 cm in men, -1.7 +/- 14.4 in women, both p < 0.0001). Irbesartan 0-10 selenium binding protein 1 Homo sapiens 113-116 17485790-9 2007 Common causes of SBP mostly were Escherichia coli and Acinettobacter baumanii, which were sensitive to antibiotic treatment of Cefoperazone, Cefotaxime and Ciprofloxacin. Cefotaxime 141-151 selenium binding protein 1 Homo sapiens 17-20 17485790-9 2007 Common causes of SBP mostly were Escherichia coli and Acinettobacter baumanii, which were sensitive to antibiotic treatment of Cefoperazone, Cefotaxime and Ciprofloxacin. Ciprofloxacin 156-169 selenium binding protein 1 Homo sapiens 17-20 17317393-8 2007 SBP and DBP were significantly lower for sevoflurane than for ketamine at all measurements from two minutes onward, and HR was lower for sevoflurane than for ketamine at two, four, and six minutes. Sevoflurane 41-52 selenium binding protein 1 Homo sapiens 0-3 17391291-8 2007 BP-lowering efficacy defined as E(max) was superior with olmesartan, (DBP/SBP mmHg: -9.0/-12.4) when compared with candesartan (-6.7/-11.3), irbesartan (-6.5/-11.2) and valsartan (-6.3/-8.9). olmesartan 57-67 selenium binding protein 1 Homo sapiens 74-77 17317393-8 2007 SBP and DBP were significantly lower for sevoflurane than for ketamine at all measurements from two minutes onward, and HR was lower for sevoflurane than for ketamine at two, four, and six minutes. Ketamine 62-70 selenium binding protein 1 Homo sapiens 0-3 17317393-10 2007 Changes in SBP, DBP, and HR caused by sevoflurane suggest that hemodynamic alterations may underlie its effects on IOP. Sevoflurane 38-49 selenium binding protein 1 Homo sapiens 11-14 17211618-11 2007 Landiolol causes a rapid and dose-dependent decrease in HR, whereas landiolol-induced changes in sBP and dBP are independent of dose. landiolol 68-77 selenium binding protein 1 Homo sapiens 97-100 17211618-15 2007 Landiolol reduces HR rapidly and in a dose-dependent manner whereas landiolol-induced changes in sBP and dBP are independent of dose. landiolol 68-77 selenium binding protein 1 Homo sapiens 97-100 17510503-4 2007 After nicorandil administration, the reduction in maximal systolic blood pressure in the aorta (Deltaa-SBP) was -14+/-15 mmHg, significantly larger than that in early systolic pressure in the radial artery (Deltar-SBP) (-9+/-12 mmHg). Nicorandil 6-16 selenium binding protein 1 Homo sapiens 103-106 17510503-4 2007 After nicorandil administration, the reduction in maximal systolic blood pressure in the aorta (Deltaa-SBP) was -14+/-15 mmHg, significantly larger than that in early systolic pressure in the radial artery (Deltar-SBP) (-9+/-12 mmHg). Nicorandil 6-16 selenium binding protein 1 Homo sapiens 214-217 17914893-9 2007 RESULTS: The average weighted reductions in SBP over 8-12 weeks were most marked with diuretics, and in particular indapamide SR 1.5 mg/day (mean change from baseline -22.2mm Hg), which reduced SBP to a greater extent than any of the other drugs evaluated (at any dosage considered). Indapamide 115-125 selenium binding protein 1 Homo sapiens 44-47 17878723-7 2007 SBP was higher in patients with premorbid hypertension, a previous history of stroke or TIA, current alcohol use, increasing age, stroke of mild to moderate severity (NIHSS 3-13) and in patients treated with antihypertensives. Alcohols 101-108 selenium binding protein 1 Homo sapiens 0-3 17953475-11 2007 The primary efficacy endpoint of change in mean seated SBP at week 12 was significantly greater with olmesartan medoxomil/HCTZ than with benazepril plus amlodipine besylate (least square [LS] mean change: -32.5 vs -26.5 mm Hg, p=0.024; LS mean treatment difference -6.0 mm Hg; 95% CI -11.1, -0.8 mm Hg). olmesartan 101-111 selenium binding protein 1 Homo sapiens 55-58 17953475-11 2007 The primary efficacy endpoint of change in mean seated SBP at week 12 was significantly greater with olmesartan medoxomil/HCTZ than with benazepril plus amlodipine besylate (least square [LS] mean change: -32.5 vs -26.5 mm Hg, p=0.024; LS mean treatment difference -6.0 mm Hg; 95% CI -11.1, -0.8 mm Hg). medoxomil 112-121 selenium binding protein 1 Homo sapiens 55-58 17953475-11 2007 The primary efficacy endpoint of change in mean seated SBP at week 12 was significantly greater with olmesartan medoxomil/HCTZ than with benazepril plus amlodipine besylate (least square [LS] mean change: -32.5 vs -26.5 mm Hg, p=0.024; LS mean treatment difference -6.0 mm Hg; 95% CI -11.1, -0.8 mm Hg). Hydrochlorothiazide 122-126 selenium binding protein 1 Homo sapiens 55-58 17953475-11 2007 The primary efficacy endpoint of change in mean seated SBP at week 12 was significantly greater with olmesartan medoxomil/HCTZ than with benazepril plus amlodipine besylate (least square [LS] mean change: -32.5 vs -26.5 mm Hg, p=0.024; LS mean treatment difference -6.0 mm Hg; 95% CI -11.1, -0.8 mm Hg). benazepril 137-147 selenium binding protein 1 Homo sapiens 55-58 17953475-11 2007 The primary efficacy endpoint of change in mean seated SBP at week 12 was significantly greater with olmesartan medoxomil/HCTZ than with benazepril plus amlodipine besylate (least square [LS] mean change: -32.5 vs -26.5 mm Hg, p=0.024; LS mean treatment difference -6.0 mm Hg; 95% CI -11.1, -0.8 mm Hg). Amlodipine 153-163 selenium binding protein 1 Homo sapiens 55-58 17953475-13 2007 BP reductions showed statistically significant differences between treatment groups favoring olmesartan medoxomil/HCTZ in both SBP and DBP at week 8. olmesartan 93-103 selenium binding protein 1 Homo sapiens 127-130 17953475-13 2007 BP reductions showed statistically significant differences between treatment groups favoring olmesartan medoxomil/HCTZ in both SBP and DBP at week 8. medoxomil 104-113 selenium binding protein 1 Homo sapiens 127-130 17953475-13 2007 BP reductions showed statistically significant differences between treatment groups favoring olmesartan medoxomil/HCTZ in both SBP and DBP at week 8. Hydrochlorothiazide 114-118 selenium binding protein 1 Homo sapiens 127-130 17914893-9 2007 RESULTS: The average weighted reductions in SBP over 8-12 weeks were most marked with diuretics, and in particular indapamide SR 1.5 mg/day (mean change from baseline -22.2mm Hg), which reduced SBP to a greater extent than any of the other drugs evaluated (at any dosage considered). Indapamide 115-125 selenium binding protein 1 Homo sapiens 194-197 17914893-11 2007 CONCLUSION: This new analysis supports the results of the earlier investigation, in that indapamide SR 1.5 mg/day appeared to be the most effective drug for producing significant reductions in SBP within 8-12 weeks, which is an essential element in optimising cardiovascular prevention among hypertensive patients. Indapamide 89-99 selenium binding protein 1 Homo sapiens 193-196 17315536-10 2006 The Emax values for the inhibitory effects on SBP and DBP of irbesartan were 14.8 +/- 1.5 and 9.8 +/- 2.1 mmHg respectively, the EC50 values were 0.29 +/- 0.11 and 0.18 +/- 0.07 microg x ml(-1), while the K(eo) values were 0.62 +/- 0.09 and 0.68 +/- 0.07 h(-1), respectively. Irbesartan 61-71 selenium binding protein 1 Homo sapiens 46-49 18409290-6 2007 The result of the amlodipine therapy (5 mg/day) was statistically significant decrease in systolic (SBP) and diastolic (DBP) blood pressure in group B. Amlodipine 18-28 selenium binding protein 1 Homo sapiens 100-103 17162147-8 2006 In patients with CKD, HOMA score and SBP were associated negatively with FMD (model R(2) = 0.28; P < 0.001), and SBP and waist-hip ratio were associated negatively with GTN-mediated dilatation (model R(2) = 0.25; P < 0.001). Nitroglycerin 172-175 selenium binding protein 1 Homo sapiens 116-119 16964741-8 2006 During +Gz, carotid sinus SBP was significantly depressed in PPM-NP and PPM-C conditions vs. Control. gz 8-10 selenium binding protein 1 Homo sapiens 26-29 17283863-5 2006 The mean reductions of morning systolic/diastolic BP (SBP/DBP) in the azelnidipine and amlodipine groups were similar (-24.1 +/- 11.8/-14.1 +/- 10.7 vs. -20.4 +/- 11.7/-12.2 +/- 7.7 mmHg). azelnidipine 70-82 selenium binding protein 1 Homo sapiens 54-57 16690175-14 2006 Children with tHcy levels above the upper reference limits (>10 micromol/L) were found to be correlated with BMI, WC, SBP, serum folate and vitamin B12 levels. thcy 14-18 selenium binding protein 1 Homo sapiens 121-124 17217710-8 2006 (3) Individual and overall trough/peak ratios of DBP and SBP in 24-hour ambulatory blood pressure monitoring were higher in olmesartan group than losartan group. olmesartan 124-134 selenium binding protein 1 Homo sapiens 57-60 17096604-13 2006 However, patients treated exclusively with Ibuprofen show similar levels of SBP than without NSAID treatment. Ibuprofen 43-52 selenium binding protein 1 Homo sapiens 76-79 17144105-5 2006 RESULTS: In the studied group, after trandolapril therapy SBP was reduced from 142.6 +/- 9,7 mmHg to 129.3 +/- 8,4 mmHg (p<0,003), DBP from 85.7 +/- 6,9 mmHg to 79.8 +/- 8,6 mmHg (p<0,01). trandolapril 37-49 selenium binding protein 1 Homo sapiens 58-61 17144105-8 2006 Young hypertensives treated with trandolapril (ACEI) showed significant decrease of SBP and DBP 2. trandolapril 33-45 selenium binding protein 1 Homo sapiens 84-87 17144105-8 2006 Young hypertensives treated with trandolapril (ACEI) showed significant decrease of SBP and DBP 2. acei 47-51 selenium binding protein 1 Homo sapiens 84-87 16861099-15 2006 At base-line, systolic blood pressure (SBP) was 116.7 (5.9) mm Hg in the sibutramine group and 118.3 (7.6) mm Hg in the placebo group; at end point, the respective SBPs were 112.4 (9.6) mm Hg and 112.6 (6.5) mm Hg. sibutramine 73-84 selenium binding protein 1 Homo sapiens 39-42 16878433-14 2006 In this latter, 8-iso-PGF2alpha showed a positive correlation with TNFalpha (p < 0.001), sCr (p < 0.001), SBP (p < 0.05) and DBP (p < 0.05). 8-epi-prostaglandin F2alpha 16-31 selenium binding protein 1 Homo sapiens 112-115 16380993-5 2006 Selenium can disrupt the androgen pathway, which has been implicated in modulating SELENBP1 expression. Selenium 0-8 selenium binding protein 1 Homo sapiens 83-91 16380993-7 2006 Interestingly, SELENBP1 mRNA and protein levels were reduced by androgen and elevated by selenium treatment in the normal HOSE cells, whereas reversed responses were observed in the ovarian cancer cell lines. Selenium 89-97 selenium binding protein 1 Homo sapiens 15-23 16380993-8 2006 These results suggest that changes of SELENBP1 expression in malignant ovarian cancer are an indicator of aberration of selenium/androgen pathways and may reveal prognostic information of ovarian cancer. Selenium 120-128 selenium binding protein 1 Homo sapiens 38-46 16229910-8 2006 RESULTS: Parallel errors by +/-5 mmHg in both SBP and DBP resulted to an identical change in GTF-derived aortic pressures, as expected. glucose tolerance factor 93-96 selenium binding protein 1 Homo sapiens 46-49 16229910-10 2006 An isolated error in brachial SBP by +/-5 mmHg was transmitted by 76% ( approximately 3.8 mmHg) to GTF-derived aortic SBP. glucose tolerance factor 99-102 selenium binding protein 1 Homo sapiens 30-33 16229910-10 2006 An isolated error in brachial SBP by +/-5 mmHg was transmitted by 76% ( approximately 3.8 mmHg) to GTF-derived aortic SBP. glucose tolerance factor 99-102 selenium binding protein 1 Homo sapiens 118-121 17163286-11 2006 Significant decreases in SBP and DBP were also observed at 3 months in the doxazosin group compared with baseline (p < 0.05), and these differences were significant (p < 0.05) compared with placebo. Doxazosin 75-84 selenium binding protein 1 Homo sapiens 25-28 16503299-7 2006 The stepwise multiple regression equations showed that the SBP and TWA predicted the high TC and high LDL-C, while the TC, age and abdominal obesity were predictors for high SBP and DBP. Technetium 90-92 selenium binding protein 1 Homo sapiens 59-62 17192130-4 2006 The aim of this analysis was to evaluate further the relationship between baseline HR, SBP, DBP and tolerability in COLA II. cola ii 116-123 selenium binding protein 1 Homo sapiens 87-90 17192130-11 2006 Seventy percent of patients in the lowest category of baseline SBP (<120 mm Hg) tolerated carvedilol versus 80% and 89% of those in the upper categories (p < 0.001). Carvedilol 93-103 selenium binding protein 1 Homo sapiens 63-66 16181727-5 2006 Participants demonstrated greater HR and SBP increases to the PASAT during the nicotine withdrawal condition. Nicotine 79-87 selenium binding protein 1 Homo sapiens 41-44 16492185-4 2006 The SBP and DBP were positively related to daily ethanol intake (p < 0.001) when adjusting for possible confounders such as age, body mass index, and smoking status. Ethanol 49-56 selenium binding protein 1 Homo sapiens 4-7 16492185-5 2006 The adjusted risk for hypertension (SBP >or= 140 mmHg or DBP >or= 90 mmHg) increased significantly when daily ethanol intake exceeded 60 g/day, and the categorical dose of interest was 60.1-90 g/day. Ethanol 116-123 selenium binding protein 1 Homo sapiens 36-39 16492185-6 2006 The BMDL and BMD of ethanol intake for increased SBP and DBP were estimated to be approximately 60 and 75 g/day, respectively. Ethanol 20-27 selenium binding protein 1 Homo sapiens 49-52 17163286-12 2006 Furthermore, significant decreases in SBP and DBP were observed at 6 months (p < 0.01) in the doxazosin group compared with baseline, and these differences were also significant (p < 0.01) compared with placebo. Doxazosin 97-106 selenium binding protein 1 Homo sapiens 38-41 17094270-4 2006 In a pharmacogenetic study composed of 107 subjects, our bivariate model has probed two haplotypes within the beta 2AR candidate gene that exert a significant effect on both SBP and DBP respond to dobutamine. Dobutamine 197-207 selenium binding protein 1 Homo sapiens 174-177 16424784-5 2006 After 12 months the SBP/DBP mean values were significantly reduced by both losartan (from 151.4/95.6 to 135.5/83.7 mm Hg, P < 0.001 versus baseline) and amlodipine (from 152.3/96.5 to 135.2/83.4 mm Hg, P < 0.001 versus baseline), with no difference between the two treatments. Losartan 75-83 selenium binding protein 1 Homo sapiens 20-23 16424784-5 2006 After 12 months the SBP/DBP mean values were significantly reduced by both losartan (from 151.4/95.6 to 135.5/83.7 mm Hg, P < 0.001 versus baseline) and amlodipine (from 152.3/96.5 to 135.2/83.4 mm Hg, P < 0.001 versus baseline), with no difference between the two treatments. Amlodipine 156-166 selenium binding protein 1 Homo sapiens 20-23 32689184-1 2005 In the Arabidopsis genome there are three highly conserved homologues of the mammalian 56-kD selenium-binding protein (SBP). Selenium 93-101 selenium binding protein 1 Homo sapiens 119-122 24678079-12 2005 At the end of week 8, the mean percentage reduction in SBP was significantly greater in the T + R group compared with that in the L + R group (24.1% vs 19.4%; P < 0.05). 2-tridecanone 92-97 selenium binding protein 1 Homo sapiens 55-58 16535839-6 2005 Logistic regression analysis demonstrated that the alcohol-drinking group"s effect rate of antihypertensive were 45% lower (P = 0.0493) in SBP drop and 76% lower (P = 0.4750) in DBP drop respectively compared with non-and alcohol-drinking groups. Alcohols 51-58 selenium binding protein 1 Homo sapiens 139-142 16181242-8 2005 Independent predictors of SBP were age and glucose in the acromegalic population, and BMI, age and glucose levels in the controls. Glucose 43-50 selenium binding protein 1 Homo sapiens 26-29 16404153-9 2005 These results suggest that the altered expression of Hsps (especially Hsp56 and Hsp60) by E2 metabolites such as E2, 16a-OHE1 and 2-ME could be closely linked to their mitogenic action. Estradiol 90-92 selenium binding protein 1 Homo sapiens 70-75 16404153-9 2005 These results suggest that the altered expression of Hsps (especially Hsp56 and Hsp60) by E2 metabolites such as E2, 16a-OHE1 and 2-ME could be closely linked to their mitogenic action. 16a-ohe1 117-125 selenium binding protein 1 Homo sapiens 70-75 16404153-9 2005 These results suggest that the altered expression of Hsps (especially Hsp56 and Hsp60) by E2 metabolites such as E2, 16a-OHE1 and 2-ME could be closely linked to their mitogenic action. 2-Methoxyestradiol 130-134 selenium binding protein 1 Homo sapiens 70-75 15944721-10 2005 Phenylpropanolamine increased SBP 5.5 mmHg (95% CI: 3.1-8.0) and DBP 4.1 mmHg (95% CI: 2.2-6.0) with no effect on pulse. Phenylpropanolamine 0-19 selenium binding protein 1 Homo sapiens 30-33 16118571-8 2005 CONCLUSION: The PAaccum reduces SBP in hypertension and prehypertension but does not appear to be related to the EE(PA-C). Protactinium 16-18 selenium binding protein 1 Homo sapiens 32-35 16154480-3 2005 OBJECTIVE: This was a study of the effects on sitting systolic BP (SBP)of 2 combinations of valsartan and hydrochlorothiazide (HCTZ) compared with valsartan monotherapy in patients with stage 2 or 3 systolic hypertension (SBP > or =160 mm Hg and < or =200 mm Hg) with or without other cardiovascular risk factors. Valsartan 92-101 selenium binding protein 1 Homo sapiens 67-70 15967467-3 2005 The SBP, which is structureless in isolation, adopts a beta-hairpin conformation in complex with the minichaperone suggesting that favorable non-specific interactions of the SPs confined to helices H and I of the apical domains can induce local secondary structures. minichaperone 101-114 selenium binding protein 1 Homo sapiens 4-7 15967467-3 2005 The SBP, which is structureless in isolation, adopts a beta-hairpin conformation in complex with the minichaperone suggesting that favorable non-specific interactions of the SPs confined to helices H and I of the apical domains can induce local secondary structures. Sodium phenolsulfonate 174-177 selenium binding protein 1 Homo sapiens 4-7 15967467-4 2005 Comparison of the dynamical fluctuations of the apo and the liganded forms of the minichaperone shows that the stability (needed for SP capture) involves favorable hydrophobic interactions and hydrogen bond network formation between the SBP and WBP, and helices H and I. sp 133-135 selenium binding protein 1 Homo sapiens 237-240 15967467-4 2005 Comparison of the dynamical fluctuations of the apo and the liganded forms of the minichaperone shows that the stability (needed for SP capture) involves favorable hydrophobic interactions and hydrogen bond network formation between the SBP and WBP, and helices H and I. Hydrogen 193-201 selenium binding protein 1 Homo sapiens 237-240 24672129-12 2005 SBP and DBP were significantly decreased from baseline with perindopril/indapamide (both, P < 0.001). Perindopril 60-71 selenium binding protein 1 Homo sapiens 0-3 24672129-12 2005 SBP and DBP were significantly decreased from baseline with perindopril/indapamide (both, P < 0.001). Indapamide 72-82 selenium binding protein 1 Homo sapiens 0-3 16154480-3 2005 OBJECTIVE: This was a study of the effects on sitting systolic BP (SBP)of 2 combinations of valsartan and hydrochlorothiazide (HCTZ) compared with valsartan monotherapy in patients with stage 2 or 3 systolic hypertension (SBP > or =160 mm Hg and < or =200 mm Hg) with or without other cardiovascular risk factors. Hydrochlorothiazide 106-125 selenium binding protein 1 Homo sapiens 67-70 16154480-14 2005 Significant additional reductions in SBP and DBP and an increase in responder rates were achieved with the addition to V160 of HCTZ12.5 and HCTZ25, with no significant effect on tolerability. v160 119-123 selenium binding protein 1 Homo sapiens 37-40 16154480-14 2005 Significant additional reductions in SBP and DBP and an increase in responder rates were achieved with the addition to V160 of HCTZ12.5 and HCTZ25, with no significant effect on tolerability. hctz12 127-133 selenium binding protein 1 Homo sapiens 37-40 16154480-14 2005 Significant additional reductions in SBP and DBP and an increase in responder rates were achieved with the addition to V160 of HCTZ12.5 and HCTZ25, with no significant effect on tolerability. hctz25 140-146 selenium binding protein 1 Homo sapiens 37-40 15953131-10 2005 SBP was negatively associated with signal AMP (median, P = 0.012) and positively associated with LAT (ulnar, P = 0.018). Adenosine Monophosphate 42-45 selenium binding protein 1 Homo sapiens 0-3 17532689-10 2005 However, both SBP and DBP were significantly lower in the olmesartan group than in the losartan group after treatment. olmesartan 58-68 selenium binding protein 1 Homo sapiens 14-17 15897788-3 2005 At the end of the study, systolic and diastolic blood pressure (SBP and DBP) were significantly reduced from 152 to 140 mm Hg and from 97 to 87 mm Hg, respectively, with doxazosin (P < 0.01). Doxazosin 170-179 selenium binding protein 1 Homo sapiens 64-67 16161947-11 2005 CONCLUSION: The treatment with ACEI drug (trandolapil) induced the significant decrease of SBP and DBP in young hypertensives. trandolapil 42-53 selenium binding protein 1 Homo sapiens 91-94 15857327-6 2005 In amlodipine group (n = 14), 24-h SBP/DBP (mmHg) decreased from 144 +/- 8/94 +/- 4 to 128 +/- 6/83 +/- 3 at the end of the third month and to 125 +/- 5/81 +/- 2 at the end of the sixth month (p < 0.0001). Amlodipine 3-13 selenium binding protein 1 Homo sapiens 35-38 15725044-10 2005 Of all the drugs studied, indapamide SR gave the greatest SBP reduction (-22.2 mm Hg). indapamide sr 26-39 selenium binding protein 1 Homo sapiens 58-61 15725044-12 2005 CONCLUSION: Indapamide SR 1.5 mg appeared to be the most effective drug for a significant reduction in SBP within 2-3 months, which is an essential element in optimizing cardiovascular prevention among hypertensive patients. indapamide sr 12-25 selenium binding protein 1 Homo sapiens 103-106 15638817-5 2005 RESULTS: After 3 weeks of treatment, values of SBP, DPB and MAP were significantly lower in the group taking l-arginine as compared with the placebo group (SBP: 134.2 +/- 2.9 vs. 143.1 +/- 2.8; DBP: 81.6 +/- 1.7 vs. 86.5 +/- 0.9; MAP: 101.8 +/- 1.5 vs. 108.0 +/- 1.2 mmHg, P < 0.01). Arginine 109-119 selenium binding protein 1 Homo sapiens 47-50 15638817-5 2005 RESULTS: After 3 weeks of treatment, values of SBP, DPB and MAP were significantly lower in the group taking l-arginine as compared with the placebo group (SBP: 134.2 +/- 2.9 vs. 143.1 +/- 2.8; DBP: 81.6 +/- 1.7 vs. 86.5 +/- 0.9; MAP: 101.8 +/- 1.5 vs. 108.0 +/- 1.2 mmHg, P < 0.01). Arginine 109-119 selenium binding protein 1 Homo sapiens 156-159 15942466-7 2005 RESULTS: CS provided a larger reduction in BP [systolic/diastolic BP (SBP/DBP): 7.3 +/- 0.4/5.4 +/- 0.3 versus 4.1 +/- 0.4/3.1 +/- 0.26 mmHg, CS versus control; P < 0.001 for both] and percentage of patients with BP < 140/90 mmHg (CS versus control: baseline, 33 versus 34%, NS; end of follow-up, 51 versus 47%, chi = 13.371; P < 0.001). Cesium 9-11 selenium binding protein 1 Homo sapiens 70-73 15897788-4 2005 SBP and DBP were reduced from 150 to 134 mm Hg and from 94 to 83 mm Hg, respectively, with irbesartan (P < 0.01). Irbesartan 91-101 selenium binding protein 1 Homo sapiens 0-3 17532689-12 2005 After 4 weeks of treatment, the reduction in BP values was larger in the olmesartan group than in the losartan group (decreases in DBP of 12.1 +/- 8.4mm Hg vs 7.2 +/- 6.8mm Hg [p < 0.005] and in SBP of 15.1 +/- 13.0mm Hg vs 10.3 +/- 10.1mm Hg [p < 0.05] for the olmesartan and losartan groups, respectively). olmesartan 73-83 selenium binding protein 1 Homo sapiens 198-201 16392299-13 2005 CONCLUSION: Valsartan significantly reduced SBP and DBP Valsartan at 160 mg/d had a significantly greater effect in reducing micro and macroalbuminuria. Valsartan 12-21 selenium binding protein 1 Homo sapiens 44-47 15724847-14 2005 Univariate analysis of the physiologic data immediately available in the field revealed that SBP of < 90 mm Hg, motor score of < 6, delayed capillary refill, and increasing pulse were significantly associated with a LSI. lsi 222-225 selenium binding protein 1 Homo sapiens 93-96 15724847-15 2005 However, multivariate analysis revealed that only SBP of < 90 mm Hg and motor score of < 6 were associated with a LSI. lsi 120-123 selenium binding protein 1 Homo sapiens 50-53 15569244-5 2005 In this report we examined the sorting of a minor protein of the protein storage vacuole, the sucrose-binding-protein homolog (SBP), along the secretory pathway employing immunoelectron microscopy on cryosectioned pea cotyledons. Sucrose 94-101 selenium binding protein 1 Homo sapiens 127-130 15569244-6 2005 SBP follows the same vesicular route into the PSV as the main storage proteins legumin and vicilin, via the dense-vesicles. Legumin 79-86 selenium binding protein 1 Homo sapiens 0-3 15824468-11 2004 Therefore, PACE+ Japan follow-up counseling was associated with a reduction in SBP, which in turn was associated with reduction in U-Na. u-na 131-135 selenium binding protein 1 Homo sapiens 79-82 15631278-3 2004 HCTZ was doubled after the first 4 weeks in non-responders (DBP > or =90 mmHg or SBP > 180 mmHg). Hydrochlorothiazide 0-4 selenium binding protein 1 Homo sapiens 84-87 15343353-9 2004 These results suggest that variants at these two AGT sites together, in conjunction with age, may be significantly associated with elevated SBP, whereas the single-site models are as good models of DBP. Diosmin 198-201 selenium binding protein 1 Homo sapiens 140-143 15607623-11 2004 There was a significant effect of the final sodium level by diet on the change in SBP over time (P = .04 for three-way interaction among diet, time of visit, and sodium). Sodium 44-50 selenium binding protein 1 Homo sapiens 82-85 15614029-7 2004 Isoproterenol increased HR, SBP and pulse pressure and decreased DBP with a comparable magnitude in both groups. Isoproterenol 0-13 selenium binding protein 1 Homo sapiens 28-31 19471794-5 2004 After receiving 1.5 g intravenous dipirone at surgery completion, he immediately developed bronchospasm, cyanosis, decreased SpO2 and SBP, culminating with cardiac arrest. dipirone 34-42 selenium binding protein 1 Homo sapiens 134-137 19471794-10 2004 Intravenous 100 mg methylene blue was then administered with increased SBP to 85 and 105 mmHg after the second dose. Methylene Blue 19-33 selenium binding protein 1 Homo sapiens 71-74 15363813-5 2004 The SBP reductions during the morning periods were comparable, but the reduction in the 24-h mean SBP was 3.4 mm Hg greater (P < .0022) for amlodipine. Amlodipine 143-153 selenium binding protein 1 Homo sapiens 98-101 15071488-5 2004 Both combination treatments, delapril-manidipine and irbesartan-hydrochlorothiazide, produced a greater reduction in systolic BP/diastolic BP (SBP/DBP) values (-27.6/21.8 mmHg and -26.4/20.2 mmHg, respectively) than the respective monotherapies (-15.2/11.7 mmHg with delapril and -16.3/11.3 mmHg with irbesartan). delapril 29-37 selenium binding protein 1 Homo sapiens 143-146 15071488-5 2004 Both combination treatments, delapril-manidipine and irbesartan-hydrochlorothiazide, produced a greater reduction in systolic BP/diastolic BP (SBP/DBP) values (-27.6/21.8 mmHg and -26.4/20.2 mmHg, respectively) than the respective monotherapies (-15.2/11.7 mmHg with delapril and -16.3/11.3 mmHg with irbesartan). manidipine 38-48 selenium binding protein 1 Homo sapiens 143-146 15071488-5 2004 Both combination treatments, delapril-manidipine and irbesartan-hydrochlorothiazide, produced a greater reduction in systolic BP/diastolic BP (SBP/DBP) values (-27.6/21.8 mmHg and -26.4/20.2 mmHg, respectively) than the respective monotherapies (-15.2/11.7 mmHg with delapril and -16.3/11.3 mmHg with irbesartan). Irbesartan 53-63 selenium binding protein 1 Homo sapiens 143-146 15071488-5 2004 Both combination treatments, delapril-manidipine and irbesartan-hydrochlorothiazide, produced a greater reduction in systolic BP/diastolic BP (SBP/DBP) values (-27.6/21.8 mmHg and -26.4/20.2 mmHg, respectively) than the respective monotherapies (-15.2/11.7 mmHg with delapril and -16.3/11.3 mmHg with irbesartan). Hydrochlorothiazide 64-83 selenium binding protein 1 Homo sapiens 143-146 15646031-12 2004 With in 2 months of GP supplementation, there was a significant decline in both systolic (SBP) and diastolic blood pressures (DBP) and a significant reduction in ox-LDL and 8-iso-PGF2alpha levels in Group I patients. gp 20-22 selenium binding protein 1 Homo sapiens 90-93 15363813-9 2004 Amlodipine was more effective in reducing SBP over the 24-h period. Amlodipine 0-10 selenium binding protein 1 Homo sapiens 42-45 15505644-9 2004 Halothane induction led to a significant drop in SBP, DBP and MAP in all patients at the end of induction. Halothane 0-9 selenium binding protein 1 Homo sapiens 49-52 15334377-10 2004 The QTc also correlated positively with the systolic (SBP) and diastolic blood pressure (DBP) (r = 0.4371, P <.0001, r = 0.3632, P =.0014, respectively). qtc 4-7 selenium binding protein 1 Homo sapiens 54-57 15302984-4 2004 The 3% ODI level was positively associated with systolic and diastolic blood pressure levels (SBP/DBP); a 5 event per hour increment of the 3% ODI level was associated with 0.8 mmHg (95% confidence interval [CI], 0.0-1.6) greater SBP and 0.7 mmHg (95% CI, 0.3-1.1) greater DBP after adjustment for age, body mass index, ethanol intake, smoking category and community. 1,8-Octanediol 7-10 selenium binding protein 1 Homo sapiens 94-97 15314741-6 2004 SBP was treated with a standard dose of a third-generation cephalosporin. Cephalosporins 59-72 selenium binding protein 1 Homo sapiens 0-3 15314741-17 2004 Third-generation cephalosporin is an effective antibiotic in SBP. Cephalosporins 17-30 selenium binding protein 1 Homo sapiens 61-64 15223851-12 2004 On average, sildenafil caused a decrease of SBP ranging from 5.1 +/- 3.9 mm Hg during the first dosing to 4.7 +/- 4.2 mm Hg during the third dosing, DBP ranged from 4.4 +/- 4.9 to 4 +/- 4.1 mm Hg, and HR increased 1.8 +/- 2.0 bpm (first dose) and 1.2 +/- 0.9 bpm (third dose). Sildenafil Citrate 12-22 selenium binding protein 1 Homo sapiens 44-47 15223851-13 2004 With vardenafil, we recorded a greater variation for SBP and DBP. Vardenafil Dihydrochloride 5-15 selenium binding protein 1 Homo sapiens 53-56 15315443-1 2004 A striking feature of sulfate (SO(4)(2-)) and molybdate (MoO(4)(2-)) transport proteins, such as SBP and ModA, which specifically bind SO(4)(2-) and MoO(4)(2-), respectively, is their ability to discriminate very similar anions with the same net charge, geometry, and hydrogen-bonding properties. Sulfates 22-29 selenium binding protein 1 Homo sapiens 97-100 15315443-1 2004 A striking feature of sulfate (SO(4)(2-)) and molybdate (MoO(4)(2-)) transport proteins, such as SBP and ModA, which specifically bind SO(4)(2-) and MoO(4)(2-), respectively, is their ability to discriminate very similar anions with the same net charge, geometry, and hydrogen-bonding properties. molybdate 46-55 selenium binding protein 1 Homo sapiens 97-100 15315443-1 2004 A striking feature of sulfate (SO(4)(2-)) and molybdate (MoO(4)(2-)) transport proteins, such as SBP and ModA, which specifically bind SO(4)(2-) and MoO(4)(2-), respectively, is their ability to discriminate very similar anions with the same net charge, geometry, and hydrogen-bonding properties. Hydrogen 268-276 selenium binding protein 1 Homo sapiens 97-100 15315443-5 2004 The calculations also help to explain the absence of positively charged Lys/Arg side chains in the anion-binding sites of SBP and ModA. Lysine 72-75 selenium binding protein 1 Homo sapiens 122-125 15315443-5 2004 The calculations also help to explain the absence of positively charged Lys/Arg side chains in the anion-binding sites of SBP and ModA. Arginine 76-79 selenium binding protein 1 Homo sapiens 122-125 15257187-7 2004 Changes in SBP and PP, but not in MBP and DBP, were more significantly associated with Per/Ind than with atenolol, with more pronounced effects using central than brachial measurements, and a longer delay in central return of wave reflections under Per/Ind. Atenolol 105-113 selenium binding protein 1 Homo sapiens 11-14 15278389-6 2004 Losartan effectively decreased systolic (SBP) and diastolic (DBP) blood pressure. Losartan 0-8 selenium binding protein 1 Homo sapiens 41-44 15302984-4 2004 The 3% ODI level was positively associated with systolic and diastolic blood pressure levels (SBP/DBP); a 5 event per hour increment of the 3% ODI level was associated with 0.8 mmHg (95% confidence interval [CI], 0.0-1.6) greater SBP and 0.7 mmHg (95% CI, 0.3-1.1) greater DBP after adjustment for age, body mass index, ethanol intake, smoking category and community. 1,8-Octanediol 7-10 selenium binding protein 1 Homo sapiens 230-233 15302984-4 2004 The 3% ODI level was positively associated with systolic and diastolic blood pressure levels (SBP/DBP); a 5 event per hour increment of the 3% ODI level was associated with 0.8 mmHg (95% confidence interval [CI], 0.0-1.6) greater SBP and 0.7 mmHg (95% CI, 0.3-1.1) greater DBP after adjustment for age, body mass index, ethanol intake, smoking category and community. 1,8-Octanediol 143-146 selenium binding protein 1 Homo sapiens 94-97 15302984-4 2004 The 3% ODI level was positively associated with systolic and diastolic blood pressure levels (SBP/DBP); a 5 event per hour increment of the 3% ODI level was associated with 0.8 mmHg (95% confidence interval [CI], 0.0-1.6) greater SBP and 0.7 mmHg (95% CI, 0.3-1.1) greater DBP after adjustment for age, body mass index, ethanol intake, smoking category and community. 1,8-Octanediol 143-146 selenium binding protein 1 Homo sapiens 230-233 15190049-15 2004 In multivariate linear regression analyses, plasma vitamin C, serum ceruloplasmin and erythrocyte membrane zinc were negatively associated with SBP (p = 0.00001) and plasma vitamin C was negatively associated with DBP (p = 0.0001). Ascorbic Acid 51-60 selenium binding protein 1 Homo sapiens 144-147 15199303-10 2004 Throughout the BP-recording, a SBP decrease of 10.1% (95% CI: 8.6-11.5) and 10.4% (95% CI: 9.0-11.8) was documented in patients with LAA and LAC respectively, while a milder drop was recorded in CE (3.7%, 95% CI: 2.4-5.0) and IUC (5.5%, 95% CI: 4.1-6.8). laa 133-136 selenium binding protein 1 Homo sapiens 31-34 15216449-8 2004 Reductions in systolic (SBP) and diastolic (DBP) blood pressures after 12 weeks were similar in both groups: In the MOX group, mean SBP (+/- SD) decreased from 154 +/- 12 to 142 +/- 17 mmHg and mean DBP from 91 +/- 9 to 83 +/- 9 mmHg. MOX 116-119 selenium binding protein 1 Homo sapiens 132-135 15296798-10 2004 RESULTS: Seated SBP and DBP increased after water instillation with increases first noted between 5 and 8 min after the water had been instilled. Water 44-49 selenium binding protein 1 Homo sapiens 16-19 15296798-11 2004 The BP remained elevated until 35 min post water increase over baseline being +36.5 mm Hg SBP and +24.3 mm Hg DBP. Water 43-48 selenium binding protein 1 Homo sapiens 90-93 24672080-19 2004 Also in the simvastatin group, 26 patients (22.6%) achieved their target SBP/DBP. Simvastatin 12-23 selenium binding protein 1 Homo sapiens 73-76 15206154-4 2004 Multiple linear regression analysis demonstrated that baPWV is improved by decreases in SBP and BMI through several lifestyle modifications. bapwv 54-59 selenium binding protein 1 Homo sapiens 88-91 15251330-13 2004 CONCLUSIONS: Diurnal and 24-hour periods of ABPM showed significant changes in SBP, DBP, and MBP after active treatment with doxazosin GITS. Doxazosin 125-134 selenium binding protein 1 Homo sapiens 79-82 24672080-28 2004 CONCLUSIONS: In this group of patients with hypercholesterolemia, the starting dosage of simvastatin (20 mg/d) was associated with reductions in SBP and DBP within 3 months of treatment in patients with hypertension, and this effect was independent of the lipid-lowering properties of the drug. Simvastatin 89-100 selenium binding protein 1 Homo sapiens 145-148 15060711-8 2004 The exercise-related differences in SBP, DP and Tsk between HY and NO were increased by water ingestion (P<0.05). Water 88-93 selenium binding protein 1 Homo sapiens 36-39 15176923-3 2004 Previous reports suggest that a new angiotensin receptor blocker, eprosartan, might have a higher efficacy to reduce SBP. eprosartan 66-76 selenium binding protein 1 Homo sapiens 117-120 15176923-16 2004 CONCLUSIONS: Eprosartan seems to be an effective drug to reduce SBP, DBP and pulse pressure with the same effectiveness in diabetics and non diabetic patients. eprosartan 13-23 selenium binding protein 1 Homo sapiens 64-67 15108003-3 2004 Double staining by anti-SBP antibody and deoxyribonuclease (DNase I) that labels monomeric G-actin or phalloidin that labels filamentous F-actin showed that the SBP-positive area was overstained by DNase I but, surprisingly, was not stained by phalloidin. Phalloidine 102-112 selenium binding protein 1 Homo sapiens 161-164 24672080-3 2004 OBJECTIVE: The aim of this study was to determine whether simvastatin 20 and 40 mg/d have an effect on systolic and diastolic blood pressure (SBP and DBP, respectively) in patients with hypercholesterolemia, and, if so, whether the effect is dose dependent and/or is related to the changes in the serum lipid profile. Simvastatin 58-69 selenium binding protein 1 Homo sapiens 142-145 15076172-4 2004 METHODS AND RESULTS: A multivariate analysis of variables associated with the risk of developing diabetes in CAPPP demonstrated that glucose, body mass index (BMI), haemoglobin (Hb), age, "SBP x Untreated" (the interaction between systolic blood pressure at baseline and newly diagnosed hypertension), cholesterol and prior antihypertensive treatment came out as risk factors. cappp 109-114 selenium binding protein 1 Homo sapiens 189-192 15293527-10 2004 CONCLUSIONS: Manidipine was safe and effective, obtaining a significant reduction in SBP and DBP from baseline. manidipine 13-23 selenium binding protein 1 Homo sapiens 85-88 14747881-6 2004 RESULTS: Both valsartan and enalapril had a clear antihypertensive effect, but the former led to a slightly greater reduction in SBP/DBP at 16 weeks (18.6+/-4.6/13.7+/-4.0 mmHg vs 15.6+/-5.1/10.9+/-3.9 mmHg; P<0.01). Valsartan 14-23 selenium binding protein 1 Homo sapiens 129-132 15038948-6 2004 In 5 studies of perindopril-indapamide versus placebo, the between-group weighted mean differences (WMDs) for both systolic and diastolic BP (SBP and DBP, respectively) favored perindopril-indapamide (SBP, -9.03 mm Hg [95% CI, -9.54 to -8.52]; DBP, -5.09 mm Hg [95% Cl, -5.42 to -4.77]; both P < 0.01 for z score for overall effect). indapamide, perindopril drug combination 16-38 selenium binding protein 1 Homo sapiens 142-145 15038948-6 2004 In 5 studies of perindopril-indapamide versus placebo, the between-group weighted mean differences (WMDs) for both systolic and diastolic BP (SBP and DBP, respectively) favored perindopril-indapamide (SBP, -9.03 mm Hg [95% CI, -9.54 to -8.52]; DBP, -5.09 mm Hg [95% Cl, -5.42 to -4.77]; both P < 0.01 for z score for overall effect). indapamide, perindopril drug combination 16-38 selenium binding protein 1 Homo sapiens 201-204 15038948-6 2004 In 5 studies of perindopril-indapamide versus placebo, the between-group weighted mean differences (WMDs) for both systolic and diastolic BP (SBP and DBP, respectively) favored perindopril-indapamide (SBP, -9.03 mm Hg [95% CI, -9.54 to -8.52]; DBP, -5.09 mm Hg [95% Cl, -5.42 to -4.77]; both P < 0.01 for z score for overall effect). indapamide, perindopril drug combination 177-199 selenium binding protein 1 Homo sapiens 142-145 15038948-6 2004 In 5 studies of perindopril-indapamide versus placebo, the between-group weighted mean differences (WMDs) for both systolic and diastolic BP (SBP and DBP, respectively) favored perindopril-indapamide (SBP, -9.03 mm Hg [95% CI, -9.54 to -8.52]; DBP, -5.09 mm Hg [95% Cl, -5.42 to -4.77]; both P < 0.01 for z score for overall effect). indapamide, perindopril drug combination 177-199 selenium binding protein 1 Homo sapiens 201-204 15038948-7 2004 In 6 studies of perindopril-indapamide versus routine antihypertensives, the between-group WMDs for SBP and DBP favored perindopril-indapamide (SBP, -3.72 mm Hg [95% CI, -7.11 to 0.33], P = 0.03 for z score for overall effect; DBP, -1.71 mm Hg [95% CI, -2.27 to -1.16], P < 0.01 for z score for overall effect). Perindopril 16-27 selenium binding protein 1 Homo sapiens 100-103 15038948-7 2004 In 6 studies of perindopril-indapamide versus routine antihypertensives, the between-group WMDs for SBP and DBP favored perindopril-indapamide (SBP, -3.72 mm Hg [95% CI, -7.11 to 0.33], P = 0.03 for z score for overall effect; DBP, -1.71 mm Hg [95% CI, -2.27 to -1.16], P < 0.01 for z score for overall effect). Perindopril 16-27 selenium binding protein 1 Homo sapiens 144-147 15038948-7 2004 In 6 studies of perindopril-indapamide versus routine antihypertensives, the between-group WMDs for SBP and DBP favored perindopril-indapamide (SBP, -3.72 mm Hg [95% CI, -7.11 to 0.33], P = 0.03 for z score for overall effect; DBP, -1.71 mm Hg [95% CI, -2.27 to -1.16], P < 0.01 for z score for overall effect). Perindopril 120-131 selenium binding protein 1 Homo sapiens 144-147 15038948-7 2004 In 6 studies of perindopril-indapamide versus routine antihypertensives, the between-group WMDs for SBP and DBP favored perindopril-indapamide (SBP, -3.72 mm Hg [95% CI, -7.11 to 0.33], P = 0.03 for z score for overall effect; DBP, -1.71 mm Hg [95% CI, -2.27 to -1.16], P < 0.01 for z score for overall effect). Indapamide 132-142 selenium binding protein 1 Homo sapiens 144-147 14747881-6 2004 RESULTS: Both valsartan and enalapril had a clear antihypertensive effect, but the former led to a slightly greater reduction in SBP/DBP at 16 weeks (18.6+/-4.6/13.7+/-4.0 mmHg vs 15.6+/-5.1/10.9+/-3.9 mmHg; P<0.01). Enalapril 28-37 selenium binding protein 1 Homo sapiens 129-132 15273436-10 2004 Cortisol levels at inclusion (r = 0.31, p = 0.02, multivariate p = 0.05 for 24-hour SBP) and in the evening were also statistically significantly related to the above BP variables. Hydrocortisone 0-8 selenium binding protein 1 Homo sapiens 84-87 14974053-7 2004 MAIN RESULTS: In 57 trials of mainly Caucasians with normal blood pressure, low sodium intake reduced SBP by -1.27 mm Hg (CI: -1.76; -0.77)(p<0.0001) and DBP by -0.54 mm Hg (CI: -0.94; -0.14) (p = 0.009) as compared to high sodium intake. Sodium 80-86 selenium binding protein 1 Homo sapiens 102-105 24936110-13 2004 Amifostine caused significant SBP and DBP reductions at 8 minutes of infusion compared with baseline in groups 1 (both P < 0.001) and 2 (P = 0.002 and P = 0.006, respectively). Amifostine 0-10 selenium binding protein 1 Homo sapiens 30-33 14974053-8 2004 In 58 trials of mainly Caucasians with elevated blood pressure, low sodium intake reduced SBP by -4.18 mm Hg (CI: -5.08; - 3.27) (p < 0.0001) and DBP by -1.98 mm Hg (CI: -2.46; -1.32) (p < 0.0001) as compared to high sodium intake. Sodium 68-74 selenium binding protein 1 Homo sapiens 90-93 14974053-11 2004 In 8 trials of blacks with normal or elevated blood pressure, low sodium intake reduced SBP by -6.44 mm Hg (CI: -9.13; -3.74) (p < 0.0001) and DBP by -1.98 mm Hg (CI: -4.75; 0.78) (p = 0.16) as compared to high sodium intake. Sodium 66-72 selenium binding protein 1 Homo sapiens 88-91 14989905-10 2004 (3) An increment of 20 mm Hg in SBP or 10 mm Hg in DBP associated with a 40% increase in incidence of MI, adjusting for age, TC and smoking. Technetium 125-127 selenium binding protein 1 Homo sapiens 32-35 17265611-7 2004 The study showed that by the end of Ramadan fasting, there was a significant improvement in the mean levels of hemoglobin (Hb), TC, TG, HDL-c, LDL-c, TC/HDL, LDL/HDL, Lp (a), APA, APB, PT and systolic (SBP) and diastolic blood pressure (DBP) that persisted for four weeks after fasting (P < 0.05). Carbon 72-73 selenium binding protein 1 Homo sapiens 202-205 14688811-4 2004 Following treatment, 24-h mean SBP (telmisartan 157 +/- 11 vs 133 +/- 7 mmHg, P<0.001; HCTZ 154 +/- 10 vs 144 +/- 11 mmHg, P<0.003) and DBP (telmisartan 96 +/- 6 vs 83 +/- 5 mmHg, P<0.001; HCTZ 95 +/- 7 vs 87 +/- 8 mmHg, P<0.003) were significantly reduced. Telmisartan 36-47 selenium binding protein 1 Homo sapiens 31-34 14688811-5 2004 Telmisartan produced significantly greater 24-h mean SBP and DBP reductions than HCTZ (P<0.001). Telmisartan 0-11 selenium binding protein 1 Homo sapiens 53-56 14688811-8 2004 In conclusion, telmisartan 80 mg was well tolerated and significantly reduced SBP, DBP and LVMI after 12 months" treatment compared with HCTZ. Telmisartan 15-26 selenium binding protein 1 Homo sapiens 78-81 15013329-5 2004 Among the entire group, SBP and DBP positively correlated with C0; Scr and SBP, with FENa. fena 85-89 selenium binding protein 1 Homo sapiens 24-27 15013329-5 2004 Among the entire group, SBP and DBP positively correlated with C0; Scr and SBP, with FENa. fena 85-89 selenium binding protein 1 Homo sapiens 75-78 15013329-6 2004 While there was a positive correlation between SBP and C0 in groups 1s and 2s (r = 0.188, P <.000; and r = 0.145, P =.040), DBP was only associated with C0 in group 1d (P =.03, r = 0.156). c0 55-57 selenium binding protein 1 Homo sapiens 47-50 14712886-6 2003 Responder rates (ABPM DBP, seated DBP, and overall [seated SBP/DBP]) at 8 weeks were significantly higher with telmisartan than with placebo (p < or = 0.01). Telmisartan 111-122 selenium binding protein 1 Homo sapiens 59-62 14578918-5 2003 Both atenolol and losartan were equally effective in reducing SBP (-22.1 and -23.1 mmHg, respectively, P< 0.01 vs baseline) and DBP (-10.3 and -11.2 mmHg, respectively, P< 0.01 vs baseline). Atenolol 5-13 selenium binding protein 1 Homo sapiens 62-65 14578918-5 2003 Both atenolol and losartan were equally effective in reducing SBP (-22.1 and -23.1 mmHg, respectively, P< 0.01 vs baseline) and DBP (-10.3 and -11.2 mmHg, respectively, P< 0.01 vs baseline). Losartan 18-26 selenium binding protein 1 Homo sapiens 62-65 14504629-4 2003 SBP, DBP, PP and the use of antihypertensive drugs increased along with the deterioration of glucose status. Glucose 93-100 selenium binding protein 1 Homo sapiens 0-3 14572676-11 2003 The CS double amplitudes are 12.5 +/- 4.1 for SBP (P = 0.019) and 7.8 +/- 2.8 mmHg for DBP (P = 0.030), with acrophases occurring on late Sunday, early Monday (at -50 degrees and -67 degrees from 00:00 h from Saturday to Sunday for SBP and DBP, respectively, with 360 degrees identical with 1 week). Cesium 4-6 selenium binding protein 1 Homo sapiens 46-49 14572676-11 2003 The CS double amplitudes are 12.5 +/- 4.1 for SBP (P = 0.019) and 7.8 +/- 2.8 mmHg for DBP (P = 0.030), with acrophases occurring on late Sunday, early Monday (at -50 degrees and -67 degrees from 00:00 h from Saturday to Sunday for SBP and DBP, respectively, with 360 degrees identical with 1 week). Cesium 4-6 selenium binding protein 1 Homo sapiens 232-235 14572676-13 2003 The CD response peaked in the early morning hours; with 24 h identical with 360 degrees and 0 degrees = local midnight, the acrophase (phi) for SBP is at -80 degrees and for DBP at -113 degrees, in keeping with earlier results from four adult subjects (SBP: -37 degrees; DBP: -42 degrees ), individual differences notwithstanding. Cadmium 4-6 selenium binding protein 1 Homo sapiens 144-147 14572676-13 2003 The CD response peaked in the early morning hours; with 24 h identical with 360 degrees and 0 degrees = local midnight, the acrophase (phi) for SBP is at -80 degrees and for DBP at -113 degrees, in keeping with earlier results from four adult subjects (SBP: -37 degrees; DBP: -42 degrees ), individual differences notwithstanding. Cadmium 4-6 selenium binding protein 1 Homo sapiens 253-256 14572682-7 2003 The effect of DB on BP was CD-dependent, the largest response occurring in the afternoon, 2-3 h before the peaks in SBP and DBP found in the reference data of the same subject. didemnins 14-16 selenium binding protein 1 Homo sapiens 116-119 12923400-5 2003 Trimethaphan 2-4 mg/min induced complete autonomic blockade and lowered SBP below 125 mmHg in all NTN and all but one MSA (to 111 +/- 3 and 97 +/- 9 mmHg). Trimethaphan 0-12 selenium binding protein 1 Homo sapiens 72-75 12817175-8 2003 RESULTS: The change from baseline in mean 24-h ambulatory SBP was -12.2 mmHg in DBPC trials and -12.3 mmHg in PROBE trials, a rounded difference of 0.2 mmHg [95% confidence interval (CI): -1.8, 2.1]. Butylated Hydroxytoluene 80-84 selenium binding protein 1 Homo sapiens 58-61 19475294-9 2003 RESULTS: SBP and DBP variations were higher in the dexmedetomidine group in M4 and M5. Dexmedetomidine 51-66 selenium binding protein 1 Homo sapiens 9-12 12946547-11 2003 When we interrupted perindopril and candesartan therapy for a 1-month washout period, changes in SBP and DBP values were significant compared with month 12 in both groups (all P < 0.05). Perindopril 20-31 selenium binding protein 1 Homo sapiens 97-100 12946547-11 2003 When we interrupted perindopril and candesartan therapy for a 1-month washout period, changes in SBP and DBP values were significant compared with month 12 in both groups (all P < 0.05). candesartan 36-47 selenium binding protein 1 Homo sapiens 97-100 13679950-5 2003 The DASH feeding trials demonstrated that with the multiple modifications in the DASH combination diet, SBP/DBP (SBP: systolic blood pressure, DBP: diastolic blood pressure) was sizably reduced, independent of calorie balance, alcohol intake, and BP reduction with decreased dietary salt. Alcohols 227-234 selenium binding protein 1 Homo sapiens 104-107 13679950-5 2003 The DASH feeding trials demonstrated that with the multiple modifications in the DASH combination diet, SBP/DBP (SBP: systolic blood pressure, DBP: diastolic blood pressure) was sizably reduced, independent of calorie balance, alcohol intake, and BP reduction with decreased dietary salt. Salts 283-287 selenium binding protein 1 Homo sapiens 104-107 12972682-4 2003 The effect sizes of sibutramine on weight and systolic (SBP) and diastolic (DBP) blood pressure changes were estimated. sibutramine 20-31 selenium binding protein 1 Homo sapiens 56-59 12946547-8 2003 A significant change occurred from baseline to month 12 during treatment with perindopril in SBP and DBP (both P < 0.01), FPG (P < 0.05), FPI (P < 0.05), TC (P < 0.05), LDL-C (P < 0.05), Lp(a) (P < 0.05), PAM (P < 0.05), and AER (P < 0.05). Perindopril 78-89 selenium binding protein 1 Homo sapiens 93-96 12946547-9 2003 Significant changes from baseline to month 12 occurred with candesartan in SBP and DBP (both P < 0.01) and AER (P < 0.05). candesartan 60-71 selenium binding protein 1 Homo sapiens 75-78 12929470-7 2003 Twelve weeks after the participants were assigned to study groups, the reductions in SBP, measured with an OMRON device, were 12.3 +/- 15.0 mmHg with Per2/Ind0.625, 8.0 +/- 16.5 mmHg with perindopril 2 mg (P = 0.001), 9.4 +/- 14.3 mmHg with indapamide 0.625 mg (P = 0.023) and 2.1 +/- 16.8 mmHg with placebo (P < 0.001) (mean +/- SD; all P values are for comparisons with Per2/Ind0.625). omron 107-112 selenium binding protein 1 Homo sapiens 85-88 14575232-5 2003 Treatment with telmisartan resulted in a significant reduction of SBP of 10.3% and 13.7% as compared to 6.6% and 10.6% in losartan group at the end of 6th and 8th weeks respectively. Telmisartan 15-26 selenium binding protein 1 Homo sapiens 66-69 12700955-7 2003 All doses of felodipine ER and placebo decreased both SBP and DBP. Felodipine 13-23 selenium binding protein 1 Homo sapiens 54-57 12714865-7 2003 RESULTS: When all patients were considered, lisinopril provided higher values of TPR [0.63/0.66 for systolic/diastolic blood pressure (SBP/DBP)], MER (1.02/0.77) and SI (1.01/0.87) than losartan (0.35/0.51, 0.60/0.60 and 0.64/0.53, respectively). Lisinopril 44-54 selenium binding protein 1 Homo sapiens 135-138 12681201-7 2003 Irbesartan therapy led to a significant (p = 0.0001) decrease in SBP (from 170.9 18.4 to 138.5 16.5 mmHg) and DBP (from 96.6 11 to 82 9 mmHg). Irbesartan 0-10 selenium binding protein 1 Homo sapiens 65-68 12569258-5 2003 A significant dependence (P < 0.05) between diastolic (DBP) or systolic (SBP) blood pressure and sodium intake was found in 16 and 5% of the participants, respectively. Sodium 100-106 selenium binding protein 1 Homo sapiens 76-79 12627358-6 2003 AC-related infection occurred in 3 patients in the SBP group and in 7 patients in the control group (P>.1). Charcoal 0-2 selenium binding protein 1 Homo sapiens 51-54 12622983-9 2003 RESULTS: Lisinopril-hidrochlorothiazide (20/12.5 mg) reduced significantly SBP (24.6 +/- 3.5 mm Hg) and DBP (14,3 +/- 0.7 mm Hg) (P<.001). lisinopril-hidrochlorothiazide 9-39 selenium binding protein 1 Homo sapiens 75-78 12715424-10 2003 BP load value measured in group 0 was 14.57 + 21.3% of SBP and 13.92 + 22.99% of DBP inappropriate results. Benzo(a)pyrene 0-2 selenium binding protein 1 Homo sapiens 55-58 12620696-6 2003 After furosemide, in 67% of patients, decreases in SBP (166 +/- 5 to 134 +/- 5 mm Hg; P <.001), DBP (82 +/- 4 to 71 +/- 4 mm Hg; P =.004), and MAP (111 +/- 3 to 92 +/- 3 mm Hg; P <.001), were associated with increases in PRA (2.1 +/- 1.2 to 5.1 +/- 1.8 ng/mL/h; P =.01) and SA (4.8 +/- 1.0 to 9.4 +/- 1.4 ng/dL; P =.01) and with decreases in ANP (101 +/- 28 to 58 +/- 11 pg/mL; P =.01) and body weight (77.5 +/- 3.6 to 76.4 +/- 3.3 kg; P =.02), findings consistent with volume mediated/salt sensitive hypertension. Furosemide 6-16 selenium binding protein 1 Homo sapiens 51-54 14598926-6 2003 Body mass index (BMI), waist hip ratio (WHR), S-Cholesterol and alcohol consumption consistently showed cross-sectional positive associations with SBP and DBP. Cholesterol 48-59 selenium binding protein 1 Homo sapiens 147-150 12572799-6 2003 Using 1H NMR-based metabonomics, it was possible to distinguish low/ normal SBP serum samples from borderline and high SBP samples. Hydrogen 6-8 selenium binding protein 1 Homo sapiens 76-79 12572799-6 2003 Using 1H NMR-based metabonomics, it was possible to distinguish low/ normal SBP serum samples from borderline and high SBP samples. Hydrogen 6-8 selenium binding protein 1 Homo sapiens 119-122 17535053-8 2003 Significant differences in favour of olmesartan medoxomil were also observed for mean 24-hour DBP and for mean daytime and 24-hour SBP by ABPM. olmesartan 37-47 selenium binding protein 1 Homo sapiens 131-134 17535053-8 2003 Significant differences in favour of olmesartan medoxomil were also observed for mean 24-hour DBP and for mean daytime and 24-hour SBP by ABPM. medoxomil 48-57 selenium binding protein 1 Homo sapiens 131-134 17535053-11 2003 CONCLUSIONS: Olmesartan medoxomil reduced daytime and 24-hour DBP and SBP, assessed by ABPM, more effectively than candesartan cilexetil at the doses tested. olmesartan 13-23 selenium binding protein 1 Homo sapiens 70-73 17535053-11 2003 CONCLUSIONS: Olmesartan medoxomil reduced daytime and 24-hour DBP and SBP, assessed by ABPM, more effectively than candesartan cilexetil at the doses tested. medoxomil 24-33 selenium binding protein 1 Homo sapiens 70-73 12535503-7 2003 MAIN RESULTS: In 57 trials of mainly Caucasians with normal blood pressure, low sodium intake reduced SBP by -1.27 mm Hg (CI: -1.76; -0.77)(p<0.0001) and DBP by -0.54 mm Hg (CI: -0.94; -0.14) (p = 0.009) as compared to high sodium intake. Sodium 80-86 selenium binding protein 1 Homo sapiens 102-105 12535503-8 2003 In 58 trials of mainly Caucasians with elevated blood pressure, low sodium intake reduced SBP by -4.18 mm Hg (CI: -5.08; - 3.27) (p < 0.0001) and DBP by -1.98 mm Hg (CI: -2.46; -1.32) (p < 0.0001) as compared to high sodium intake. Sodium 68-74 selenium binding protein 1 Homo sapiens 90-93 12535503-11 2003 In 8 trials of blacks with normal or elevated blood pressure, low sodium intake reduced SBP by -6.44 mm Hg (CI: -9.13; -3.74) (p < 0.0001) and DBP by -1.98 mm Hg (CI: -4.75; 0.78) (p = 0.16) as compared to high sodium intake. Sodium 66-72 selenium binding protein 1 Homo sapiens 88-91 14598926-6 2003 Body mass index (BMI), waist hip ratio (WHR), S-Cholesterol and alcohol consumption consistently showed cross-sectional positive associations with SBP and DBP. Alcohols 64-71 selenium binding protein 1 Homo sapiens 147-150 14598926-7 2003 One mmol/L higher S-Cholesterol at baseline predicted an increase in SBP by 1.16 mm Hg (confidence interval, CI: 0.25; 2.07) over 6 years. Cholesterol 20-31 selenium binding protein 1 Homo sapiens 69-72 12544436-9 2003 The association between DBP and SBP by tertiles, and spatial functions (Block Design and Benton Visual Retention test) remained after controlling for education, marital status, smoking, alcohol and physical activity, and intermediates such as arteriosclerotic manifestations (block design, beta = 0.17; = 0.029) in multiple regression models. Alcohols 186-193 selenium binding protein 1 Homo sapiens 32-35 12466044-8 2002 Tet lowered SBP, left ventricular weight to body weight ratio, vascular media thickness, media to lumen ratio, cardiac and vascular wet weight, and collagen content. tetrandrine 0-3 selenium binding protein 1 Homo sapiens 12-15 12778851-11 2003 SBP was higher in men with bb genotype than in the other genotypes (p: 0.007). boeravinone B 27-29 selenium binding protein 1 Homo sapiens 0-3 12778851-13 2003 CONCLUSIONS: Healthy men with higher levels of vitamin D have higher levels of SBP and DBP. Vitamin D 47-56 selenium binding protein 1 Homo sapiens 79-82 12778851-14 2003 Moreover, men with bb genotype have the highest levels of SBP. boeravinone B 19-21 selenium binding protein 1 Homo sapiens 58-61 12454325-1 2002 BACKGROUND: In guidelines for the primary prevention of cardiovascular disease, systolic blood pressure (SBP) or diastolic blood pressure (DBP) is treated with medication at lower levels of risk than those at which statin treatment is recommended for cholesterol lowering. Cholesterol 251-262 selenium binding protein 1 Homo sapiens 105-108 12410853-14 2002 CONCLUSIONS: Candesartan cilexetil significantly reduced SBP and DBP and increased control (61.2%) of BP in hypertensive menopausal women. candesartan 13-24 selenium binding protein 1 Homo sapiens 57-60 12410853-14 2002 CONCLUSIONS: Candesartan cilexetil significantly reduced SBP and DBP and increased control (61.2%) of BP in hypertensive menopausal women. Cyclohexyl propan-2-yl carbonate 25-34 selenium binding protein 1 Homo sapiens 57-60 12463106-9 2002 At the end of the study, it was found that the vitamin E supplement had caused a remarkable decrease in SBP (-24% in DG versus -1.6% in PG) and a less remarkable decrease in DBP (-12.5% in DG versus -6.2% in PG) (p < 0.05). Vitamin E 47-56 selenium binding protein 1 Homo sapiens 104-107 12522893-6 2002 SBP was reduced in irbesartan group from 157.7 +/- 11.2 to 131.0 +/- 8.7 mmHg (12th week, p < 0.001). Irbesartan 19-29 selenium binding protein 1 Homo sapiens 0-3 12522893-8 2002 In fosinopril group SBP was reduced from 147.9 +/- 11.7 to 132.2 +/- 12.4 mmHg (p < 0.001) and DBP decreases from 92.3 +/- 6.3 to 84.0 +/- 5.4 mmHg (p < 0.001). Fosinopril 3-13 selenium binding protein 1 Homo sapiens 20-23 12522893-11 2002 BP reduction was significant in fosinopril group from the first month (SBP 140.7 +/- 12.2, p = 0.021; DBP 87.2 +/- 6.2, p = 0.003). Benzo(a)pyrene 0-2 selenium binding protein 1 Homo sapiens 71-74 12522893-11 2002 BP reduction was significant in fosinopril group from the first month (SBP 140.7 +/- 12.2, p = 0.021; DBP 87.2 +/- 6.2, p = 0.003). Fosinopril 32-42 selenium binding protein 1 Homo sapiens 71-74 12234896-8 2002 Administration of 92% O(2) + 8% CO(2) significantly increased SBP, MAP, and PR (p <0.001 each, versus baseline), whereas the other gas mixtures had little effect on systemic haemodynamics. Oxygen 22-26 selenium binding protein 1 Homo sapiens 62-65 12234896-8 2002 Administration of 92% O(2) + 8% CO(2) significantly increased SBP, MAP, and PR (p <0.001 each, versus baseline), whereas the other gas mixtures had little effect on systemic haemodynamics. Carbon Dioxide 32-37 selenium binding protein 1 Homo sapiens 62-65 12370842-1 2002 The purpose of the present study was to investigate the relationships among the resting systolic (SBP) and diastolic blood pressure (DBP) or SBP response during exercise with insulin resistance evaluated by a homeostasis model (HOMA-IR), abdominal fat accumulation (visceral fat area [VFA], subcutaneous fat area [SFA]) by computed tomography (CT), and an estimation of the maximal oxygen uptake (V*O2max) in 63 Japanese middle-aged male patients with type 2 diabetes mellitus (type 2 DM). Oxygen 382-388 selenium binding protein 1 Homo sapiens 98-101 12452320-7 2002 In women (n=950), the pooled betas were -0.014 (0.01) for SBP (p<0.05) and -0.021 (0.00) for DBP (p<0.01). betas 29-34 selenium binding protein 1 Homo sapiens 58-61 12370842-8 2002 The exercise intensity at the double product breaking point (DPBP), which strongly correlated with the exercise intensity at the lactate threshold, was used as an index for the SBP response to standardized exercise intensity. Lactic Acid 129-136 selenium binding protein 1 Homo sapiens 177-180 12370842-10 2002 The change in SBP (deltaSBP = SBP@DPBP - resting SBP) was significantly and positively associated with log area under the curve for glucose (log AUCPG) during a 75-g oral glucose tolerance test (OGTT). Glucose 132-139 selenium binding protein 1 Homo sapiens 14-17 12370842-10 2002 The change in SBP (deltaSBP = SBP@DPBP - resting SBP) was significantly and positively associated with log area under the curve for glucose (log AUCPG) during a 75-g oral glucose tolerance test (OGTT). Glucose 132-139 selenium binding protein 1 Homo sapiens 24-27 12370842-10 2002 The change in SBP (deltaSBP = SBP@DPBP - resting SBP) was significantly and positively associated with log area under the curve for glucose (log AUCPG) during a 75-g oral glucose tolerance test (OGTT). Glucose 132-139 selenium binding protein 1 Homo sapiens 24-27 12370842-10 2002 The change in SBP (deltaSBP = SBP@DPBP - resting SBP) was significantly and positively associated with log area under the curve for glucose (log AUCPG) during a 75-g oral glucose tolerance test (OGTT). Glucose 171-178 selenium binding protein 1 Homo sapiens 14-17 12370842-10 2002 The change in SBP (deltaSBP = SBP@DPBP - resting SBP) was significantly and positively associated with log area under the curve for glucose (log AUCPG) during a 75-g oral glucose tolerance test (OGTT). Glucose 171-178 selenium binding protein 1 Homo sapiens 24-27 12370842-10 2002 The change in SBP (deltaSBP = SBP@DPBP - resting SBP) was significantly and positively associated with log area under the curve for glucose (log AUCPG) during a 75-g oral glucose tolerance test (OGTT). Glucose 171-178 selenium binding protein 1 Homo sapiens 24-27 12358141-6 2002 (b) After adjustment for age, SBP and DBP showed a significant positive association with body mass index, urinary sodium (Na) excretion, and total cholesterol (TC) to high-density lipoprotein (HDL) cholesterol ratio (TC/HDL). Sodium 114-120 selenium binding protein 1 Homo sapiens 30-33 12195129-11 2002 Losartan and atenolol significantly decreased SBP and DBP from baseline after 6, 12, 24 and 36 weeks. Losartan 0-8 selenium binding protein 1 Homo sapiens 46-49 12195129-11 2002 Losartan and atenolol significantly decreased SBP and DBP from baseline after 6, 12, 24 and 36 weeks. Atenolol 13-21 selenium binding protein 1 Homo sapiens 46-49 12185552-9 2002 RESULTS: Based on weighted mean and compared with placebo, sumatriptan 3 mg and 6 mg increased SBP by 3.3 mmHg ( P=0.023) and 6.4 mmHg ( P<0.001) and DBP by 5.0 mmHg ( P=0.006) and 7.5 mmHg ( P<0.001), respectively. Sumatriptan 59-70 selenium binding protein 1 Homo sapiens 95-98 12425202-9 2002 RESULTS: Rilmenidine treatment resulted in normalisation of blood pressure (BP) or significant (decrease of SBP/DBP = 20/10 mm Hg) blood pressure decrease in 69%, 22% of subjects, respectively. Rilmenidine 9-20 selenium binding protein 1 Homo sapiens 108-111 12131561-5 2002 Lacidipine compared with placebo exerted a significant antihypertensive effect, lowering SBP and DBP both at baseline and either during or after exercise test. lacidipine 0-10 selenium binding protein 1 Homo sapiens 89-92 12172328-2 2002 A low-dose combination of perindopril (Per) and indapamide (Ind) has been shown to reduce more SBP than atenolol for the same DBP reduction. Perindopril 26-37 selenium binding protein 1 Homo sapiens 95-98 12172328-2 2002 A low-dose combination of perindopril (Per) and indapamide (Ind) has been shown to reduce more SBP than atenolol for the same DBP reduction. Perindopril 39-42 selenium binding protein 1 Homo sapiens 95-98 12172328-2 2002 A low-dose combination of perindopril (Per) and indapamide (Ind) has been shown to reduce more SBP than atenolol for the same DBP reduction. Indapamide 48-58 selenium binding protein 1 Homo sapiens 95-98 12172328-2 2002 A low-dose combination of perindopril (Per) and indapamide (Ind) has been shown to reduce more SBP than atenolol for the same DBP reduction. Indapamide 60-63 selenium binding protein 1 Homo sapiens 95-98 12358141-6 2002 (b) After adjustment for age, SBP and DBP showed a significant positive association with body mass index, urinary sodium (Na) excretion, and total cholesterol (TC) to high-density lipoprotein (HDL) cholesterol ratio (TC/HDL). Cholesterol 147-158 selenium binding protein 1 Homo sapiens 30-33 12358141-6 2002 (b) After adjustment for age, SBP and DBP showed a significant positive association with body mass index, urinary sodium (Na) excretion, and total cholesterol (TC) to high-density lipoprotein (HDL) cholesterol ratio (TC/HDL). Technetium 160-162 selenium binding protein 1 Homo sapiens 30-33 12358141-6 2002 (b) After adjustment for age, SBP and DBP showed a significant positive association with body mass index, urinary sodium (Na) excretion, and total cholesterol (TC) to high-density lipoprotein (HDL) cholesterol ratio (TC/HDL). Cholesterol 198-209 selenium binding protein 1 Homo sapiens 30-33 12358141-7 2002 SBP and DBP tended to be negatively associated with 24 h urinary potassium (K) and magnesium (Mg) excretion. Potassium 65-74 selenium binding protein 1 Homo sapiens 0-3 12358141-7 2002 SBP and DBP tended to be negatively associated with 24 h urinary potassium (K) and magnesium (Mg) excretion. Magnesium 83-92 selenium binding protein 1 Homo sapiens 0-3 12358141-7 2002 SBP and DBP tended to be negatively associated with 24 h urinary potassium (K) and magnesium (Mg) excretion. Magnesium 94-96 selenium binding protein 1 Homo sapiens 0-3 11857593-9 2002 RESULTS: LPSb bound promptly to monocytes in EDTA- and heparin-treated blood. Edetic Acid 45-49 selenium binding protein 1 Homo sapiens 9-13 12078940-6 2002 RESULTS: The DBP and SBP values obtained with BZ+AM were, respectively, 2.7 and 3.7 mmHg lower than those obtained with CP+HT (both p < 0.001 vs. CP+HT). Quinuclidinyl Benzilate 46-48 selenium binding protein 1 Homo sapiens 21-24 12119799-4 2002 The DASH-Sodium trial demonstrates significant increases in SBP and DBP, with sodium intake greater than 65 mmol/d (= 3.7 g NaCl--see equivalencies in Appendix A) and with the usual American diet (versus the DASH diet). Sodium 9-15 selenium binding protein 1 Homo sapiens 60-63 11849460-7 2002 RESULTS: Black race and female gender were both associated with significantly greater systolic (SBP) and diastolic (DBP) blood pressure responses to hydrochlorothiazide. Hydrochlorothiazide 149-168 selenium binding protein 1 Homo sapiens 96-99 11857593-9 2002 RESULTS: LPSb bound promptly to monocytes in EDTA- and heparin-treated blood. Heparin 55-62 selenium binding protein 1 Homo sapiens 9-13 11857593-10 2002 In EDTA-treated blood, membrane-bound LPSb decreased after 60 min of incubation, whereas it remained detectable in heparinized blood during the 6 h of incubation. Edetic Acid 3-7 selenium binding protein 1 Homo sapiens 38-42 11857593-13 2002 CONCLUSION: Detection of membrane-bound LPSb on monocytes differed in EDTA or heparin-treated blood, and cell activation was better obtained in heparinized blood. Edetic Acid 70-74 selenium binding protein 1 Homo sapiens 40-44 11857593-13 2002 CONCLUSION: Detection of membrane-bound LPSb on monocytes differed in EDTA or heparin-treated blood, and cell activation was better obtained in heparinized blood. Heparin 78-85 selenium binding protein 1 Homo sapiens 40-44 12523679-9 2002 SBP was positively correlated to BMI and plasma cholesterol. Cholesterol 48-59 selenium binding protein 1 Homo sapiens 0-3 11929332-5 2002 Treatment for 8 weeks with candesartan cilexetil 16 mg/hydrochlorothiazide 12.5 mg or candesartan cilexetil 16 mg induced SBP/DBP reductions of 12.0/7.5 mm Hg and 7.5/5.5mm Hg, respectively (p < 0.05 both comparisons). candesartan cilexetil 27-48 selenium binding protein 1 Homo sapiens 122-125 11913598-9 2002 Change in urinary sodium-to-creatinine ratios of 3 consecutive pooled overnight 8-hour urine collections correlated with changes in 24-hour ambulatory SBP (r = 0.294, P<.001) and DBP (r = 0.193, P<.05); however, change in total urinary sodium content was uncorrelated. Sodium 18-24 selenium binding protein 1 Homo sapiens 151-154 11913598-9 2002 Change in urinary sodium-to-creatinine ratios of 3 consecutive pooled overnight 8-hour urine collections correlated with changes in 24-hour ambulatory SBP (r = 0.294, P<.001) and DBP (r = 0.193, P<.05); however, change in total urinary sodium content was uncorrelated. Creatinine 28-38 selenium binding protein 1 Homo sapiens 151-154 11913598-9 2002 Change in urinary sodium-to-creatinine ratios of 3 consecutive pooled overnight 8-hour urine collections correlated with changes in 24-hour ambulatory SBP (r = 0.294, P<.001) and DBP (r = 0.193, P<.05); however, change in total urinary sodium content was uncorrelated. Sodium 242-248 selenium binding protein 1 Homo sapiens 151-154 11929332-5 2002 Treatment for 8 weeks with candesartan cilexetil 16 mg/hydrochlorothiazide 12.5 mg or candesartan cilexetil 16 mg induced SBP/DBP reductions of 12.0/7.5 mm Hg and 7.5/5.5mm Hg, respectively (p < 0.05 both comparisons). Hydrochlorothiazide 55-74 selenium binding protein 1 Homo sapiens 122-125 11929332-5 2002 Treatment for 8 weeks with candesartan cilexetil 16 mg/hydrochlorothiazide 12.5 mg or candesartan cilexetil 16 mg induced SBP/DBP reductions of 12.0/7.5 mm Hg and 7.5/5.5mm Hg, respectively (p < 0.05 both comparisons). candesartan 27-38 selenium binding protein 1 Homo sapiens 122-125 11929332-5 2002 Treatment for 8 weeks with candesartan cilexetil 16 mg/hydrochlorothiazide 12.5 mg or candesartan cilexetil 16 mg induced SBP/DBP reductions of 12.0/7.5 mm Hg and 7.5/5.5mm Hg, respectively (p < 0.05 both comparisons). Cyclohexyl propan-2-yl carbonate 39-48 selenium binding protein 1 Homo sapiens 122-125 11929332-6 2002 Moreover, data from a randomised, double-blind, placebo-controlled, dose-finding study in 1038 patients with mild to moderate hypertension showed that the greatest reductions in SBP/DBP were achieved by candesartan cilexetil 16 mg/hydrochlorothiazide 12.5 mg. candesartan cilexetil 203-224 selenium binding protein 1 Homo sapiens 178-181 11929332-6 2002 Moreover, data from a randomised, double-blind, placebo-controlled, dose-finding study in 1038 patients with mild to moderate hypertension showed that the greatest reductions in SBP/DBP were achieved by candesartan cilexetil 16 mg/hydrochlorothiazide 12.5 mg. Hydrochlorothiazide 231-250 selenium binding protein 1 Homo sapiens 178-181 11752105-12 2002 Edrophonium may enhance (lower dose) or reduce (higher dose) cardiovascular autonomic drive in humans, as evidenced by the significant changes it evokes in HFP of the RRI (parasympathetic drive), and in the HFP and LFP of SBP (sympathetic drive). Edrophonium 0-11 selenium binding protein 1 Homo sapiens 222-225 11840225-9 2002 At week 12, mean increases from baseline supine SBP and DBP, respectively, were 1.6 and 1.7 mm Hg for the sibutramine group vs increases of 0.4 and 1.3 mm Hg for the placebo group. sibutramine 106-117 selenium binding protein 1 Homo sapiens 48-51 11840671-9 2002 However, the changes in SBP and HR at incision were significantly suppressed by addition of N2O (changes in SBP and HR: 41.6 +/- 20.4 mmHg and 35.4 +/- 12.5 bpm in the sevoflurane group vs. 24.6 +/- 10.2 mmHg and 18.1 +/- 9.5 bpm in the sevoflurane/N2O group, P < 0.01). Nitrous Oxide 92-95 selenium binding protein 1 Homo sapiens 24-27 11840671-9 2002 However, the changes in SBP and HR at incision were significantly suppressed by addition of N2O (changes in SBP and HR: 41.6 +/- 20.4 mmHg and 35.4 +/- 12.5 bpm in the sevoflurane group vs. 24.6 +/- 10.2 mmHg and 18.1 +/- 9.5 bpm in the sevoflurane/N2O group, P < 0.01). Nitrous Oxide 92-95 selenium binding protein 1 Homo sapiens 108-111 11840671-9 2002 However, the changes in SBP and HR at incision were significantly suppressed by addition of N2O (changes in SBP and HR: 41.6 +/- 20.4 mmHg and 35.4 +/- 12.5 bpm in the sevoflurane group vs. 24.6 +/- 10.2 mmHg and 18.1 +/- 9.5 bpm in the sevoflurane/N2O group, P < 0.01). Sevoflurane 168-179 selenium binding protein 1 Homo sapiens 24-27 11840671-9 2002 However, the changes in SBP and HR at incision were significantly suppressed by addition of N2O (changes in SBP and HR: 41.6 +/- 20.4 mmHg and 35.4 +/- 12.5 bpm in the sevoflurane group vs. 24.6 +/- 10.2 mmHg and 18.1 +/- 9.5 bpm in the sevoflurane/N2O group, P < 0.01). Sevoflurane 237-248 selenium binding protein 1 Homo sapiens 24-27 11840671-9 2002 However, the changes in SBP and HR at incision were significantly suppressed by addition of N2O (changes in SBP and HR: 41.6 +/- 20.4 mmHg and 35.4 +/- 12.5 bpm in the sevoflurane group vs. 24.6 +/- 10.2 mmHg and 18.1 +/- 9.5 bpm in the sevoflurane/N2O group, P < 0.01). Nitrous Oxide 249-252 selenium binding protein 1 Homo sapiens 24-27 12474774-6 2002 Antihypertensive therapy with telmisartan had a favorable effect, i.e. significantly decreased the rest BP--both SBP (152.5 +/- 11.4 mmHg vs. 139.2 +/- 12.3 mmHg, p < 0.001) and DBP (100.0 +/- 4.6 mmHg vs. 88.7 +/- 6.2 mmHg, p < 0.001). Telmisartan 30-41 selenium binding protein 1 Homo sapiens 113-116 12474774-8 2002 When repeating the exercise test after 12 weeks of telmisartan treatment we detected the significant decrease of BP at maximal workload, i.e. SBP decreased from 230.9 +/- 11.4 mmHg to 211.3 +/- 12.7 mmHg, p < 0.05 and DBP decreased from 124.6 +/- 7.5 mmHg to 109.7 +/- 9.7 mmHg, p < 0.05. Telmisartan 51-62 selenium binding protein 1 Homo sapiens 142-145 11828715-5 2001 Alcohol intake positively correlated to systolic and diastolic blood pressure (SBP and DBP) and high-density lipoprotein cholesterol (HDLC). Alcohols 0-7 selenium binding protein 1 Homo sapiens 79-82 12537696-4 2002 LPSb bound to monocytes was detected after 5 min of incubation in both groups, with a more pronounced decay in SP. sp 111-113 selenium binding protein 1 Homo sapiens 0-4 25696028-8 2002 Nitrates and NO-donors reduce SBP more than DBP because of their effects on the large conduit arteries. Nitrates 0-8 selenium binding protein 1 Homo sapiens 30-33 11806817-7 2001 In order to reach the target BP (sitting SBP <150 mmHg), the first line agent, nitrendipine, could be associated with enalapril and/or hydrochlorothiazide. Nitrendipine 82-94 selenium binding protein 1 Homo sapiens 41-44 11848262-9 2001 CONCLUSIONS: The proven efficacy on DBP and SBP, and the good safety profile, confirm that the new low-dose combination of 2 mg perindopril and 0.625 mg indapamide is a valuable option in the first-line treatment of hypertension. Perindopril 128-139 selenium binding protein 1 Homo sapiens 44-47 11687919-4 2001 At the end of double-blind treatment, patients receiving telmisartan 80 mg/HCTZ 12.5 mg had significant additional decrements in clinic SBP/DBP over telmisartan 80 mg of -5.7/-3.1 mm Hg (P < 0.01). Telmisartan 57-68 selenium binding protein 1 Homo sapiens 136-139 11687919-4 2001 At the end of double-blind treatment, patients receiving telmisartan 80 mg/HCTZ 12.5 mg had significant additional decrements in clinic SBP/DBP over telmisartan 80 mg of -5.7/-3.1 mm Hg (P < 0.01). Hydrochlorothiazide 75-79 selenium binding protein 1 Homo sapiens 136-139 11806817-7 2001 In order to reach the target BP (sitting SBP <150 mmHg), the first line agent, nitrendipine, could be associated with enalapril and/or hydrochlorothiazide. Enalapril 121-130 selenium binding protein 1 Homo sapiens 41-44 11806817-7 2001 In order to reach the target BP (sitting SBP <150 mmHg), the first line agent, nitrendipine, could be associated with enalapril and/or hydrochlorothiazide. Hydrochlorothiazide 138-157 selenium binding protein 1 Homo sapiens 41-44 11412807-13 2001 A strong positive correlation was observed between blood pressure (SBP and DBP) and body mass index, total serum cholesterol and sodium to potassium ratio. Cholesterol 113-124 selenium binding protein 1 Homo sapiens 67-70 11710785-8 2001 Cilnidipine, but not nifedipine, significantly reduced white coat effects on SBP and HR. cilnidipine 0-11 selenium binding protein 1 Homo sapiens 77-80 12092220-3 2001 Treatment of SBP is made with third generation cephalosporins with immediate favorable evolution. Cephalosporins 47-61 selenium binding protein 1 Homo sapiens 13-16 11434650-9 2001 RESULTS: In the pilot study, ARG reduced the SBP in HD patients from 171.5 +/- 7.5 mmHg (baseline) to 142.8 +/- 8.3 mmHg (p = .028). Arginine 29-32 selenium binding protein 1 Homo sapiens 45-48 11434650-14 2001 CONCLUSIONS: Oral preparations of ARG (+/-CanO) were well tolerated for up to 60 consecutive days and had favorable effects on SBP and DBP in hypertensive KT and HD patients. Arginine 34-37 selenium binding protein 1 Homo sapiens 127-130 11434650-14 2001 CONCLUSIONS: Oral preparations of ARG (+/-CanO) were well tolerated for up to 60 consecutive days and had favorable effects on SBP and DBP in hypertensive KT and HD patients. Rapeseed Oil 39-46 selenium binding protein 1 Homo sapiens 127-130 11675940-8 2001 Multiple regression analysis revealed that the reduction in SBP was significantly and positively associated with the reduction in log sigmaIRI and the reduction in log 24h-urinary norepinephrine excretion at the end of Study I. Norepinephrine 180-194 selenium binding protein 1 Homo sapiens 60-63 11412807-13 2001 A strong positive correlation was observed between blood pressure (SBP and DBP) and body mass index, total serum cholesterol and sodium to potassium ratio. Sodium 129-135 selenium binding protein 1 Homo sapiens 67-70 11412807-13 2001 A strong positive correlation was observed between blood pressure (SBP and DBP) and body mass index, total serum cholesterol and sodium to potassium ratio. Potassium 139-148 selenium binding protein 1 Homo sapiens 67-70 11325073-11 2001 4) Body mass index and the ratio of sodium to potassium excretion showed significant and positive associations with SBP and DBP in multiple linear regression analyses. Sodium 36-42 selenium binding protein 1 Homo sapiens 116-119 11325073-11 2001 4) Body mass index and the ratio of sodium to potassium excretion showed significant and positive associations with SBP and DBP in multiple linear regression analyses. Potassium 46-55 selenium binding protein 1 Homo sapiens 116-119 11204308-11 2001 RESULTS: Ambulatory SBP and pulse pressure (PP) (24 h, daytime, night-time averages) and their variability indices (24 h SD) were always significantly correlated with CBMmax and Mmax (P0.01 -0.001), and the correlations remained significant after adjustment for age, gender and smoking. cbmmax 167-173 selenium binding protein 1 Homo sapiens 20-23 11688765-5 2001 Pulse pressure (PP, the SBP-DBP difference) was also significantly (p < 0.01) reduced by delapril (5.7+/-6.2 and 3.3+/-3.8 mmHg, CPP and APP). delapril 92-100 selenium binding protein 1 Homo sapiens 24-27 11212979-7 2001 In the ISH subgroup, indapamide SR 1.5 mg tends to have greater efficacy than hydrochlorothiazide 25 mg in reducing the SBP (-24.7 versus -18.5 mmHg, respectively; equivalence P = 0.117), while similar results are obtained with amlodipine 5 mg (-23 mmHg, equivalence P < 0.001). Indapamide 21-31 selenium binding protein 1 Homo sapiens 120-123 10904026-7 2000 The potential clinical relevance of caffeine-induced BP changes is seen in the BPs that reached the hypertensive range (SBP >/=140 mm Hg or DBP >/=90 mm Hg) after caffeine. Caffeine 36-44 selenium binding protein 1 Homo sapiens 120-123 11226830-0 2000 The sex steroid binding protein (SBP or SHBG) of human plasma: identification of Tyr-57 and Met-107 in the steroid binding site. Tyrosine 81-84 selenium binding protein 1 Homo sapiens 33-36 11226830-0 2000 The sex steroid binding protein (SBP or SHBG) of human plasma: identification of Tyr-57 and Met-107 in the steroid binding site. Steroids 8-15 selenium binding protein 1 Homo sapiens 33-36 11226830-1 2000 Tyrosine-57 (Y57) and methionine-107 (M107) have been identified in the binding site of the sex steroid binding protein (SBP) (or sex hormone binding globulin) of human plasma by replacing the two amino acids with a number of residues of varying structure. Tyrosine 0-8 selenium binding protein 1 Homo sapiens 121-124 11226830-1 2000 Tyrosine-57 (Y57) and methionine-107 (M107) have been identified in the binding site of the sex steroid binding protein (SBP) (or sex hormone binding globulin) of human plasma by replacing the two amino acids with a number of residues of varying structure. Methionine 22-32 selenium binding protein 1 Homo sapiens 121-124 11132612-10 2000 RESULTS: Mean changes from baseline in SBP/DBP for men taking antihypertensive medication were -3.6/-1.9 mmHg for those receiving sildenafil and -0.8/-0.1 mmHg for those receiving placebo compared with -2.2/-2.0 mmHg and -0.1/0.4 mmHg, respectively, for men not taking antihypertensive medication. Sildenafil Citrate 130-140 selenium binding protein 1 Homo sapiens 39-42 11221155-20 2000 The SBP and DBP were highly correlated with each other (r = 0.75***, df = 4351) and they also showed highly significant positive correlation (r = 0.08***-0.13***, df = 2441-3301) with TC and GL. Technetium 184-186 selenium binding protein 1 Homo sapiens 4-7 11221155-20 2000 The SBP and DBP were highly correlated with each other (r = 0.75***, df = 4351) and they also showed highly significant positive correlation (r = 0.08***-0.13***, df = 2441-3301) with TC and GL. Glucose 191-193 selenium binding protein 1 Homo sapiens 4-7 11137411-10 2000 With the DxTek device calibrated to intraarterial pressure, comparison of the DxTek pressure to intraarterial pressure resulted in a bias < OR = 0.5 mmHg for all three pressures and an average precision of 10.1 mmHg for SBP, 6.0 mmHg for DBP, and 6.7 mmHg for MAP. dxtek 9-14 selenium binding protein 1 Homo sapiens 223-226 11137411-10 2000 With the DxTek device calibrated to intraarterial pressure, comparison of the DxTek pressure to intraarterial pressure resulted in a bias < OR = 0.5 mmHg for all three pressures and an average precision of 10.1 mmHg for SBP, 6.0 mmHg for DBP, and 6.7 mmHg for MAP. dxtek 78-83 selenium binding protein 1 Homo sapiens 223-226 11137411-11 2000 With the DxTek device calibrated to the oscillometric pressure, the DxTek pressure compared to the intraarterial pressure resulted in average biases of -5.1, -0.8, and -2.2 mmHg and average precisions of 11.1, 7.7, and 8.1 mmHg for SBP, DBP, and MAP, respectively. dxtek 9-14 selenium binding protein 1 Homo sapiens 232-235 11137411-11 2000 With the DxTek device calibrated to the oscillometric pressure, the DxTek pressure compared to the intraarterial pressure resulted in average biases of -5.1, -0.8, and -2.2 mmHg and average precisions of 11.1, 7.7, and 8.1 mmHg for SBP, DBP, and MAP, respectively. dxtek 68-73 selenium binding protein 1 Homo sapiens 232-235 11016794-9 2000 (c) In the Japanese sample, multiple linear regression analyses (using a stepwise procedure) showed that SBP had a significant positive association with BMI and sodium excretion, and a significant negative association with magnesium excretion, while DBP had a significant positive association with BMI and a significant negative association with the 3MH to creatinine ratio (3MH/Cre). Sodium 161-167 selenium binding protein 1 Homo sapiens 105-108 11016794-9 2000 (c) In the Japanese sample, multiple linear regression analyses (using a stepwise procedure) showed that SBP had a significant positive association with BMI and sodium excretion, and a significant negative association with magnesium excretion, while DBP had a significant positive association with BMI and a significant negative association with the 3MH to creatinine ratio (3MH/Cre). Magnesium 223-232 selenium binding protein 1 Homo sapiens 105-108 11016794-9 2000 (c) In the Japanese sample, multiple linear regression analyses (using a stepwise procedure) showed that SBP had a significant positive association with BMI and sodium excretion, and a significant negative association with magnesium excretion, while DBP had a significant positive association with BMI and a significant negative association with the 3MH to creatinine ratio (3MH/Cre). 3-methylhistidine 350-353 selenium binding protein 1 Homo sapiens 105-108 11016794-9 2000 (c) In the Japanese sample, multiple linear regression analyses (using a stepwise procedure) showed that SBP had a significant positive association with BMI and sodium excretion, and a significant negative association with magnesium excretion, while DBP had a significant positive association with BMI and a significant negative association with the 3MH to creatinine ratio (3MH/Cre). Creatinine 357-367 selenium binding protein 1 Homo sapiens 105-108 11016794-9 2000 (c) In the Japanese sample, multiple linear regression analyses (using a stepwise procedure) showed that SBP had a significant positive association with BMI and sodium excretion, and a significant negative association with magnesium excretion, while DBP had a significant positive association with BMI and a significant negative association with the 3MH to creatinine ratio (3MH/Cre). 3-methylhistidine 375-378 selenium binding protein 1 Homo sapiens 105-108 11016794-9 2000 (c) In the Japanese sample, multiple linear regression analyses (using a stepwise procedure) showed that SBP had a significant positive association with BMI and sodium excretion, and a significant negative association with magnesium excretion, while DBP had a significant positive association with BMI and a significant negative association with the 3MH to creatinine ratio (3MH/Cre). (+)-germacrene A 379-382 selenium binding protein 1 Homo sapiens 105-108 11016794-10 2000 In the Chinese sample, both SBP and DBP showed a significant positive association with BMI and sodium, and a significant negative association with 3MH/Cre. Sodium 95-101 selenium binding protein 1 Homo sapiens 28-31 10904026-4 2000 Caffeine raised both systolic and diastolic BP (SBP and DBP, respectively; P<0.0001 for both) in all groups. Caffeine 0-8 selenium binding protein 1 Homo sapiens 48-51 10904026-5 2000 However, an ANCOVA revealed that the strongest response to caffeine was observed among diagnosed men, followed by the stage 1 and high-normal groups and then by the normal and optimal groups (SBP F(4),(175)=5.06, P<0.0001; DBP F(4,175)=3.02, P<0.02). Caffeine 59-67 selenium binding protein 1 Homo sapiens 192-195 11101201-6 2000 Losartan induced a significant (p < 0.001) decrease in SBP, DBP, and MBP versus baseline values both at 6 months and at 12 months. Losartan 0-8 selenium binding protein 1 Homo sapiens 58-61 10834426-5 2000 RESULTS: During hyperglycemia, there were significant increments of systolic (sBP) (from 115.5 +/- 9.1 to 120.3 +/- 8.2 mmHg, P < 0.01) and diastolic (dBP) (from 70.3 +/- 7.8 to 79.7 +/- 5.3 mmHg, P < 0.01) blood pressure, as well as heart rate (from 75.2 +/- 7.8 to 80.8 +/- 5.4 beats/min, P < 0.01) and plasma catecholamines (P < 0.05). Catecholamines 321-335 selenium binding protein 1 Homo sapiens 78-81 10912743-3 2000 This study assessed the effects of chronic treatment with low doses of aspirin (100 mg/day) on clinic and ambulatory systolic (SBP) and diastolic (DBP) BP in hypertensives on chronic, stable antihypertensive therapy. Aspirin 71-78 selenium binding protein 1 Homo sapiens 127-130 10834426-9 2000 L-Arginine produced a fall in sBP and dBP to baseline values and normalized squatting ratios. Arginine 0-10 selenium binding protein 1 Homo sapiens 30-33 10774784-3 2000 After 3 months of follow-up, a greater reduction of systolic (SBP) and diastolic (DBP) blood pressure values was observed in HC-S patients (ASBP/DBP, -11.3 +/-3/-10.6 +/- 2%) when compared with both HC-D (deltaSBP/DBP, -6.6 +/- 2/-6.1 +/- 2%; p < 0.05) and NC-D (deltaSBP/DBP, -6.9 +/- 2/-6.8 +/- 1.5%; p < 0.05). asbp 140-144 selenium binding protein 1 Homo sapiens 62-65 10837840-12 2000 Significant dose-response relationships to caffeine were seen only for SBP, heart rate, and skin temperature. Caffeine 43-51 selenium binding protein 1 Homo sapiens 71-74 10770262-7 2000 The results showed that (1) Sodium was positively, and 3MH negatively associated with systolic and diastolic BP (SBP, DBP) in both the total sample and in those who were not administered anti-hypertensive drugs; these associations were all significant (p< 0.05), and remained so after adjustment for age, sex, body mass index [BMI, weight (kg)/height (m2)], alcohol intake and potassium excretion. Sodium 28-34 selenium binding protein 1 Homo sapiens 113-116 10770262-9 2000 In general, subjects who had higher sodium and lower 3MH levels had higher mean SBP and DBP. Sodium 36-42 selenium binding protein 1 Homo sapiens 80-83 10770262-9 2000 In general, subjects who had higher sodium and lower 3MH levels had higher mean SBP and DBP. 3-methylhistidine 53-56 selenium binding protein 1 Homo sapiens 80-83 11070420-7 2000 CONCLUSIONS: Elevated Na(+) (and possibly Cl(-)) in combination with high NO(-)(3) concentrations in drinking water leads to an increase of SBP and MAP in fourth and fifth graders. Water 110-115 selenium binding protein 1 Homo sapiens 140-143 10726717-12 2000 Reductions in sodium intake, insulin levels and sympathetic tone combined with possible improvements in arterial compliance induce persistent 24 h reductions in SBP and pulse BP. Sodium 14-20 selenium binding protein 1 Homo sapiens 161-164 10833799-12 2000 CONCLUSIONS: The morning rise of systolic BP is associated with an increase of ADP-induced and spontaneous platelet aggregability in the patients with mild to moderate essential hypertension and apparently that association is more pronounced at high values of morning BP (more than 20% from mean nocturnal values of SBP). Adenosine Diphosphate 79-82 selenium binding protein 1 Homo sapiens 316-319 10475144-10 1999 DTZ limited these increases to 21% for SBP, 5% for DBP, and 44% for HR (p < 0.05 for drug effect). Diltiazem 0-3 selenium binding protein 1 Homo sapiens 39-42 10708304-0 1999 Interactions of 16alpha-[18F]-fluoroestradiol (FES) with sex steroid binding protein (SBP). 16-fluoroestradiol 16-45 selenium binding protein 1 Homo sapiens 86-89 10708304-0 1999 Interactions of 16alpha-[18F]-fluoroestradiol (FES) with sex steroid binding protein (SBP). 16-fluoroestradiol 47-50 selenium binding protein 1 Homo sapiens 86-89 10708304-5 1999 The binding of [18F]-FES metabolites to SBP was also measured. 16-fluoroestradiol 21-24 selenium binding protein 1 Homo sapiens 40-43 10708304-7 1999 Typically about 45% of [18F]-FES in circulating plasma was bound to SBP, but this fraction was dependent on the concentration of SBP in plasma. 16-fluoroestradiol 29-32 selenium binding protein 1 Homo sapiens 68-71 10708304-7 1999 Typically about 45% of [18F]-FES in circulating plasma was bound to SBP, but this fraction was dependent on the concentration of SBP in plasma. 16-fluoroestradiol 29-32 selenium binding protein 1 Homo sapiens 129-132 11715454-9 1999 In NT group, serum leptin concentrations were correlated with SBP (P < 0.05). nt 3-5 selenium binding protein 1 Homo sapiens 62-65 10466461-6 1999 RESULTS: Resting PECO2 was an independent predictor of SBP in women (beta = 0.215; P<0.0015; overall r2 = 0.27; P<0.0001), and accounted for more than 10% of the variance in SBP in women over age 50 years. peco2 17-22 selenium binding protein 1 Homo sapiens 55-58 10466461-6 1999 RESULTS: Resting PECO2 was an independent predictor of SBP in women (beta = 0.215; P<0.0015; overall r2 = 0.27; P<0.0001), and accounted for more than 10% of the variance in SBP in women over age 50 years. peco2 17-22 selenium binding protein 1 Homo sapiens 180-183 10466461-9 1999 CONCLUSIONS: PECO2 is an independent determinant of resting SBP in women, especially those aged 50 years or more. peco2 13-18 selenium binding protein 1 Homo sapiens 60-63 10408586-4 1999 When all trials were pooled, a chronic high NaCl diet significantly increased mean SBP and DBP by 5.58 mm Hg (95%Cl 4.31-6.85) and 3.5 mm Hg (95%Cl 2.62-4.38) respectively. Sodium Chloride 44-48 selenium binding protein 1 Homo sapiens 83-86 10529004-1 1999 Plasma sex hormone-binding globulin (SHBG or SBP), the specific carrier for estradiol and androgens, after binding to its membrane receptor (SHBG-R), causes a significant increase of cAMP in the presence of estradiol, in both breast (MCF-7) and prostate (LNCaP) cancer cells maintained in serum-free medium. Estradiol 76-85 selenium binding protein 1 Homo sapiens 45-48 10529004-1 1999 Plasma sex hormone-binding globulin (SHBG or SBP), the specific carrier for estradiol and androgens, after binding to its membrane receptor (SHBG-R), causes a significant increase of cAMP in the presence of estradiol, in both breast (MCF-7) and prostate (LNCaP) cancer cells maintained in serum-free medium. Cyclic AMP 183-187 selenium binding protein 1 Homo sapiens 45-48 10529004-1 1999 Plasma sex hormone-binding globulin (SHBG or SBP), the specific carrier for estradiol and androgens, after binding to its membrane receptor (SHBG-R), causes a significant increase of cAMP in the presence of estradiol, in both breast (MCF-7) and prostate (LNCaP) cancer cells maintained in serum-free medium. Estradiol 207-216 selenium binding protein 1 Homo sapiens 45-48 10425617-9 1999 Moreover, we found a statistically significant correlation between blood pressure fall with atenolol and baseline heart rate (r = 0.107, P < 0.001 for SBP, and r = 0.142, p < 0.001 for DBP). Atenolol 92-100 selenium binding protein 1 Homo sapiens 154-157 10371365-7 1999 Lisinopril produced a transient decrease in mean 24-h ABP (mm Hg) at 28 days (SBP = -9.0 +/- 2.3, DBP = -5.7 +/- 1.3; P < .01), which returned to pretreatment values by 56 days of therapy. Lisinopril 0-10 selenium binding protein 1 Homo sapiens 78-81 10408586-5 1999 There was a significant association between the level of NaCl intake and SBP (P = 0.05, r2 = 0.37) but not DBP (P = 0.76, r2 = 0.01). Sodium Chloride 57-61 selenium binding protein 1 Homo sapiens 73-76 10408586-7 1999 These data suggest that a chronic high NaCl diet in elderly patients with essential hypertension is associated with an increase in SBP and DBP, the association is significant for both SBP and DBP but more marked for SBP than DBP, the effect is more pronounced the older the patient and NaCl dose strongly predicts SBP in older patients. Sodium Chloride 39-43 selenium binding protein 1 Homo sapiens 131-134 10408586-7 1999 These data suggest that a chronic high NaCl diet in elderly patients with essential hypertension is associated with an increase in SBP and DBP, the association is significant for both SBP and DBP but more marked for SBP than DBP, the effect is more pronounced the older the patient and NaCl dose strongly predicts SBP in older patients. Sodium Chloride 39-43 selenium binding protein 1 Homo sapiens 184-187 10408586-7 1999 These data suggest that a chronic high NaCl diet in elderly patients with essential hypertension is associated with an increase in SBP and DBP, the association is significant for both SBP and DBP but more marked for SBP than DBP, the effect is more pronounced the older the patient and NaCl dose strongly predicts SBP in older patients. Sodium Chloride 39-43 selenium binding protein 1 Homo sapiens 184-187 10408586-7 1999 These data suggest that a chronic high NaCl diet in elderly patients with essential hypertension is associated with an increase in SBP and DBP, the association is significant for both SBP and DBP but more marked for SBP than DBP, the effect is more pronounced the older the patient and NaCl dose strongly predicts SBP in older patients. Sodium Chloride 39-43 selenium binding protein 1 Homo sapiens 184-187 10408586-7 1999 These data suggest that a chronic high NaCl diet in elderly patients with essential hypertension is associated with an increase in SBP and DBP, the association is significant for both SBP and DBP but more marked for SBP than DBP, the effect is more pronounced the older the patient and NaCl dose strongly predicts SBP in older patients. Sodium Chloride 286-290 selenium binding protein 1 Homo sapiens 131-134 10369409-4 1999 The levels were lower for the deglycosylated mutants indicating that oligosaccharide side chains may play a role in SBP secretion. Oligosaccharides 69-84 selenium binding protein 1 Homo sapiens 116-119 10339990-10 1999 Increased SBP by application of 0.4 microgram/kg/min phenylephrine divided by 0.4 (alpha-sens) was evaluated. Phenylephrine 53-66 selenium binding protein 1 Homo sapiens 10-13 10028925-7 1999 Both the SBP and diastolic (D) BP were decreased at rest by azelnidipine treatment (from 158 +/- 10/97 +/- 7 to 145 +/- 14/90 +/- 9 mm Hg). azelnidipine 60-72 selenium binding protein 1 Homo sapiens 9-12 10028925-8 1999 Azelnidipine significantly decreased both SBP and DBP during exercise (SBP, F = 6.09, p < 0.05, Fi = 0.612, NS; DBP, F = 17.78, p < 0.001, Fi = 0.298, NS). azelnidipine 0-12 selenium binding protein 1 Homo sapiens 42-45 10028925-8 1999 Azelnidipine significantly decreased both SBP and DBP during exercise (SBP, F = 6.09, p < 0.05, Fi = 0.612, NS; DBP, F = 17.78, p < 0.001, Fi = 0.298, NS). azelnidipine 0-12 selenium binding protein 1 Homo sapiens 71-74 9833600-6 1998 RESULTS: Both lisinopril and losartan significantly reduced SBP (by a mean of 20.2 and 17.2 mmHg, respectively) and DBP (by a mean of 15.2 and 12.3 mmHg, respectively), with no difference between the two treatments. Lisinopril 14-24 selenium binding protein 1 Homo sapiens 60-63 9972377-2 1999 METHODS: Patients of the Outpatient Clinic of Cheyenne Veterans Affairs Medical Center, Wyoming, receiving nifedipine ER for the management of hypertension (systolic BP or SBP > 140 mm Hg and diastolic BP or DBP > 90 mm Hg), participated in this study. Nifedipine 107-117 selenium binding protein 1 Homo sapiens 172-175 9833600-6 1998 RESULTS: Both lisinopril and losartan significantly reduced SBP (by a mean of 20.2 and 17.2 mmHg, respectively) and DBP (by a mean of 15.2 and 12.3 mmHg, respectively), with no difference between the two treatments. Losartan 29-37 selenium binding protein 1 Homo sapiens 60-63 9715782-5 1998 The primary analysis of ABP data revealed that both lisinopril and HCTZ effectively lowered mean 24-h systolic (SBP) and diastolic (DBP) blood pressure compared with placebo, (mean change from baseline SBP/DBP: -12.0/-8.2, -10.6/-5.5, and -0.3/-0.5 mm Hg, respectively); however, lisinopril lowered DBP better than HCTZ (P < .05). Lisinopril 52-62 selenium binding protein 1 Homo sapiens 112-115 9781930-6 1998 Both perindopril and losartan reduced SBP (by a mean of 20.2 mm Hg, p < 0.001 vs. placebo; and 15.8 mm Hg, p = 0.002 vs. placebo, respectively) and DBP (by a mean of 15.2 mm Hg, p = 0.001 vs. placebo, and 11.8 mm Hg, p = 0.01 vs. placebo respectively), with no difference between the two treatments. Perindopril 5-16 selenium binding protein 1 Homo sapiens 38-41 9781930-6 1998 Both perindopril and losartan reduced SBP (by a mean of 20.2 mm Hg, p < 0.001 vs. placebo; and 15.8 mm Hg, p = 0.002 vs. placebo, respectively) and DBP (by a mean of 15.2 mm Hg, p = 0.001 vs. placebo, and 11.8 mm Hg, p = 0.01 vs. placebo respectively), with no difference between the two treatments. Losartan 21-29 selenium binding protein 1 Homo sapiens 38-41 9793811-10 1998 Three minutes after SA significant decrease in the following parameters was observed: SBP in group PL compared with the other three groups (p = 0.004), DBP in group PL vs. groups C5 and C2.5 (p = 0.002), and MBP in group PL vs. groups C5 and C2.5 (p = 0.003). sa 20-22 selenium binding protein 1 Homo sapiens 86-89 9926907-8 1998 African-American and lower SES youth exhibited higher SBP and DBP values than whites and higher SES youth. Selenium 27-30 selenium binding protein 1 Homo sapiens 54-57 9715782-5 1998 The primary analysis of ABP data revealed that both lisinopril and HCTZ effectively lowered mean 24-h systolic (SBP) and diastolic (DBP) blood pressure compared with placebo, (mean change from baseline SBP/DBP: -12.0/-8.2, -10.6/-5.5, and -0.3/-0.5 mm Hg, respectively); however, lisinopril lowered DBP better than HCTZ (P < .05). Lisinopril 52-62 selenium binding protein 1 Homo sapiens 202-205 9715782-5 1998 The primary analysis of ABP data revealed that both lisinopril and HCTZ effectively lowered mean 24-h systolic (SBP) and diastolic (DBP) blood pressure compared with placebo, (mean change from baseline SBP/DBP: -12.0/-8.2, -10.6/-5.5, and -0.3/-0.5 mm Hg, respectively); however, lisinopril lowered DBP better than HCTZ (P < .05). Hydrochlorothiazide 67-71 selenium binding protein 1 Homo sapiens 112-115 9715782-5 1998 The primary analysis of ABP data revealed that both lisinopril and HCTZ effectively lowered mean 24-h systolic (SBP) and diastolic (DBP) blood pressure compared with placebo, (mean change from baseline SBP/DBP: -12.0/-8.2, -10.6/-5.5, and -0.3/-0.5 mm Hg, respectively); however, lisinopril lowered DBP better than HCTZ (P < .05). Hydrochlorothiazide 67-71 selenium binding protein 1 Homo sapiens 202-205 9582047-7 1998 DATA SYNTHESIS: In 58 trials of hypertensive persons, the effect of reduced sodium intake as measured by urinary sodium excretion (mean, 118 mmol/24 h) on SBP was 3.9 mm Hg (95% confidence interval [CI], 3.0-4.8 mm Hg) (P<.001) and on DBP was 1.9 mm Hg (95% CI, 1.3-2.5 mm Hg) (P<.001). Sodium 76-82 selenium binding protein 1 Homo sapiens 155-158 9679983-6 1998 hSP56 expression was especially high in normal tissues that appear to benefit from the cancer-protective action of dietary selenium and was low in many neoplastic cells. Selenium 123-131 selenium binding protein 1 Homo sapiens 0-5 9669433-7 1998 SBP, DBP, and MAP decreased statistically and clinically significantly during UF+HD with L-Ca dialysate and were significantly lower with the use of L-Ca dialysate compared with H-Ca dialysate. chicoric acid 89-93 selenium binding protein 1 Homo sapiens 0-3 9669433-7 1998 SBP, DBP, and MAP decreased statistically and clinically significantly during UF+HD with L-Ca dialysate and were significantly lower with the use of L-Ca dialysate compared with H-Ca dialysate. chicoric acid 149-153 selenium binding protein 1 Homo sapiens 0-3 10099062-5 1998 In the presence of metoclopramide and metoclopramide plus labetalol, however, handgrip induced lesser increases in blood pressure (changes in SBP/DBP: 23/7 mm Hg, P < 0.01, and 18/4 mm Hg, P < 0.01, for metoclopramide and metoclopramide plus labetalol treatments). Metoclopramide 38-52 selenium binding protein 1 Homo sapiens 142-145 10099062-5 1998 In the presence of metoclopramide and metoclopramide plus labetalol, however, handgrip induced lesser increases in blood pressure (changes in SBP/DBP: 23/7 mm Hg, P < 0.01, and 18/4 mm Hg, P < 0.01, for metoclopramide and metoclopramide plus labetalol treatments). Labetalol 58-67 selenium binding protein 1 Homo sapiens 142-145 10099062-5 1998 In the presence of metoclopramide and metoclopramide plus labetalol, however, handgrip induced lesser increases in blood pressure (changes in SBP/DBP: 23/7 mm Hg, P < 0.01, and 18/4 mm Hg, P < 0.01, for metoclopramide and metoclopramide plus labetalol treatments). Metoclopramide 38-52 selenium binding protein 1 Homo sapiens 142-145 10099062-5 1998 In the presence of metoclopramide and metoclopramide plus labetalol, however, handgrip induced lesser increases in blood pressure (changes in SBP/DBP: 23/7 mm Hg, P < 0.01, and 18/4 mm Hg, P < 0.01, for metoclopramide and metoclopramide plus labetalol treatments). Metoclopramide 38-52 selenium binding protein 1 Homo sapiens 142-145 9705037-9 1998 Partial correlations of SBP and DBP with the 3-day averages were 0.257 (P < 0.01) and 0.210 (P < 0.05) for sodium; 0.223 (P < 0.05) and 0.222 (P < 0.05) for potassium; 0.127 and 0.091 for urinary volume; and -0.033 and 0.014 for creatinine. Potassium 169-178 selenium binding protein 1 Homo sapiens 24-27 9705037-9 1998 Partial correlations of SBP and DBP with the 3-day averages were 0.257 (P < 0.01) and 0.210 (P < 0.05) for sodium; 0.223 (P < 0.05) and 0.222 (P < 0.05) for potassium; 0.127 and 0.091 for urinary volume; and -0.033 and 0.014 for creatinine. Creatinine 241-251 selenium binding protein 1 Homo sapiens 24-27 9725782-5 1998 It showed that (1) benazepril could reduce blood pressure significantly (SBP decreased from 174.8 +/- 12.0 mmHg to 151.5 +/- 9.0 mmHg, p <0.001; DBP decreased from 108.0 +/- 8.2 mmHg to 95.3 +/- 9.0 mmHg, p <0.001). benazepril 19-29 selenium binding protein 1 Homo sapiens 73-76 10099062-2 1998 Although all treatments were effective in reducing resting systolic (SBP) and diastolic (DBP) blood pressures, the combination of metoclopramide and labetalol appeared to provide a greater decrease (changes in SBP/DBP: 15/11 mm Hg, P < 0.05; from 149 +/- 4/95 +/- 4 mm Hg to 134 +/- 5/84 +/- 3 mm Hg) than did labetalol alone (changes in SBP/DBP: 10/9 mm Hg, P < 0.05; from 149 +/- 4/95 +/- 4 to 139 +/- 4/86 +/- 3 mm Hg). Metoclopramide 130-144 selenium binding protein 1 Homo sapiens 210-213 10099062-2 1998 Although all treatments were effective in reducing resting systolic (SBP) and diastolic (DBP) blood pressures, the combination of metoclopramide and labetalol appeared to provide a greater decrease (changes in SBP/DBP: 15/11 mm Hg, P < 0.05; from 149 +/- 4/95 +/- 4 mm Hg to 134 +/- 5/84 +/- 3 mm Hg) than did labetalol alone (changes in SBP/DBP: 10/9 mm Hg, P < 0.05; from 149 +/- 4/95 +/- 4 to 139 +/- 4/86 +/- 3 mm Hg). Metoclopramide 130-144 selenium binding protein 1 Homo sapiens 210-213 10099062-2 1998 Although all treatments were effective in reducing resting systolic (SBP) and diastolic (DBP) blood pressures, the combination of metoclopramide and labetalol appeared to provide a greater decrease (changes in SBP/DBP: 15/11 mm Hg, P < 0.05; from 149 +/- 4/95 +/- 4 mm Hg to 134 +/- 5/84 +/- 3 mm Hg) than did labetalol alone (changes in SBP/DBP: 10/9 mm Hg, P < 0.05; from 149 +/- 4/95 +/- 4 to 139 +/- 4/86 +/- 3 mm Hg). Labetalol 149-158 selenium binding protein 1 Homo sapiens 210-213 10099062-2 1998 Although all treatments were effective in reducing resting systolic (SBP) and diastolic (DBP) blood pressures, the combination of metoclopramide and labetalol appeared to provide a greater decrease (changes in SBP/DBP: 15/11 mm Hg, P < 0.05; from 149 +/- 4/95 +/- 4 mm Hg to 134 +/- 5/84 +/- 3 mm Hg) than did labetalol alone (changes in SBP/DBP: 10/9 mm Hg, P < 0.05; from 149 +/- 4/95 +/- 4 to 139 +/- 4/86 +/- 3 mm Hg). Labetalol 149-158 selenium binding protein 1 Homo sapiens 210-213 10099062-5 1998 In the presence of metoclopramide and metoclopramide plus labetalol, however, handgrip induced lesser increases in blood pressure (changes in SBP/DBP: 23/7 mm Hg, P < 0.01, and 18/4 mm Hg, P < 0.01, for metoclopramide and metoclopramide plus labetalol treatments). Metoclopramide 19-33 selenium binding protein 1 Homo sapiens 142-145 9582047-7 1998 DATA SYNTHESIS: In 58 trials of hypertensive persons, the effect of reduced sodium intake as measured by urinary sodium excretion (mean, 118 mmol/24 h) on SBP was 3.9 mm Hg (95% confidence interval [CI], 3.0-4.8 mm Hg) (P<.001) and on DBP was 1.9 mm Hg (95% CI, 1.3-2.5 mm Hg) (P<.001). Sodium 113-119 selenium binding protein 1 Homo sapiens 155-158 9582047-8 1998 In 56 trials of normotensive persons, the effect of reduced sodium intake (mean, 160 mmol/24 h) on SBP was 1.2 mm Hg (95% CI, 0.6-1.8 mm Hg) (P<.001) and on DBP was 0.26 mm Hg (95% CI, -0.3-0.9 mm Hg) (P=.12). Sodium 60-66 selenium binding protein 1 Homo sapiens 99-102 9607387-10 1998 Fewer patients had high nocturnal SBP with amlodipine (39.3%) than nifedipine SR (71.4%; P = .042). Amlodipine 43-53 selenium binding protein 1 Homo sapiens 34-37 9758081-1 1998 In studies of the effects of salt intake on blood pressure (SBP, MBP, DBP), influences on heart rate (HR) are usually neglected even though the longterm load on both left ventricle (LV) and systemic arteries (SA) is better related to the product of HR x SBP (or MBP) than to pressure alone. Salts 29-33 selenium binding protein 1 Homo sapiens 60-63 9758081-7 1998 By contrast, in salt-sensitive man, HR reflex reductions to increased salt intake were almost absent despite substantial SBP elevations, suggesting the influence of a CNS suppression of bulbar reflex centres combined with CNS neurohormonal interference with renal salt volume excretion, as in SHR. Salts 16-20 selenium binding protein 1 Homo sapiens 121-124 9657539-9 1998 The reduction in ambulatory 24-h SBP/DBP was 13/9 mmHg for fosinopril and 15/14 for atenolol, ambulatory DBP being significantly more reduced by atenolol (p = 0.03 for difference in treatment effect). Fosinopril 59-69 selenium binding protein 1 Homo sapiens 33-36 9657539-9 1998 The reduction in ambulatory 24-h SBP/DBP was 13/9 mmHg for fosinopril and 15/14 for atenolol, ambulatory DBP being significantly more reduced by atenolol (p = 0.03 for difference in treatment effect). Atenolol 84-92 selenium binding protein 1 Homo sapiens 33-36 9657539-9 1998 The reduction in ambulatory 24-h SBP/DBP was 13/9 mmHg for fosinopril and 15/14 for atenolol, ambulatory DBP being significantly more reduced by atenolol (p = 0.03 for difference in treatment effect). Atenolol 145-153 selenium binding protein 1 Homo sapiens 33-36 9537607-8 1998 On day 5 the mean systolic (SBP) and mean diastolic blood pressures (DBP) in the dexfenfluramine group were lower than those of the control group (SBP: 114+/-7 mm Hg in the dexfenfluramine group compared with 124+/-12 mm Hg in the control group, P < 0.05; DBP: 70+/-9 mm Hg in the dexfenfluramine group compared with 76+/-10 mm Hg in the control group, P < 0.05). Dexfenfluramine 81-96 selenium binding protein 1 Homo sapiens 28-31 9537607-8 1998 On day 5 the mean systolic (SBP) and mean diastolic blood pressures (DBP) in the dexfenfluramine group were lower than those of the control group (SBP: 114+/-7 mm Hg in the dexfenfluramine group compared with 124+/-12 mm Hg in the control group, P < 0.05; DBP: 70+/-9 mm Hg in the dexfenfluramine group compared with 76+/-10 mm Hg in the control group, P < 0.05). Dexfenfluramine 81-96 selenium binding protein 1 Homo sapiens 147-150 10456135-5 1998 In the lacidipine group, SBP was significantly reduced from 157 +/- 14 mmHg to 146 +/- 24 mmHg (P < 0.00001) and DBP from 90 +/- 9 mmHG to 87 +/- 15 mmHg (P < 0.00001) with BP normalisation rates of 67% and 79% at 4 weeks and 12 weeks, respectively. lacidipine 7-17 selenium binding protein 1 Homo sapiens 25-28 10456135-6 1998 In the hydrochlorothiazide group, SBP was significantly reduced from 16.4 +/- 19 mmHg to 141 +/- 17 mmHg (P < 0.00001) and DBP from 102 +/- 6 mmHG to 89 +/- 7 mmHg (P < 0.00001) with normalisation rates of 77% and 82% at 4 weeks and 12 weeks respectively. Hydrochlorothiazide 7-26 selenium binding protein 1 Homo sapiens 34-37 9438918-8 1997 Clonidine administration decreased SBP, DBP and NE levels in PreMW, in PeriMW and in PeriMWE without any difference between the groups (F = 1.2, p = NS; F = 0.5, p = NS and F = 1.3, P = NS respectively). Clonidine 0-9 selenium binding protein 1 Homo sapiens 35-38 16379774-0 1998 Calcium supplementation during pregnancy was associated with lower SBP in the children. Calcium 0-7 selenium binding protein 1 Homo sapiens 67-70 9638033-11 1998 There was a wide range in the resting BP response to caffeine (combined SBP and DBP ranged from 10-39 mmHg) suggesting that there are marked differences in sensitivity to caffeine, irrespective of individuals" consumption habits. Caffeine 53-61 selenium binding protein 1 Homo sapiens 72-75 9349282-6 1997 However, unlike most lea genes, ABA regulation of the sbp gene seems to occur in a very restricted fashion, being confined only to particular stages of embryo development. Abscisic Acid 32-35 selenium binding protein 1 Homo sapiens 54-57 9360028-6 1997 A small (approximately 2 mmHg in the 24h mean of SBP), but statistically significant, BP reduction was found when 500 mg/day ASA was given to healthy volunteers at Time 2. Aspirin 125-128 selenium binding protein 1 Homo sapiens 49-52 9356840-7 1997 CONCLUSION: Ceftriaxone is a safe and effective option for the treatment of SBP. Ceftriaxone 12-23 selenium binding protein 1 Homo sapiens 76-79 9399380-5 1997 Caffeine in the beverage rapidly augmented skin conductance responses but, in contrast to the effect of hot water, reduced the skin temperature response and increased SBP (+2.8 mmHg) and DBP (+2.1 mmHg) 30-60 min post-consumption. Caffeine 0-8 selenium binding protein 1 Homo sapiens 167-170 9360001-9 1997 After 3 weeks of treatment with one capsule daily, mean SBP/DBP reduction from baseline (24 h after last medication intake) in the R/C combination group was -19.6/ -17.0 mmHg, in the enalapril group -6.1/ -9.5 mmHg (between-group comparison: 2p < 0.01 for both parameters). Enalapril 183-192 selenium binding protein 1 Homo sapiens 56-59 9128792-22 1997 Subtotal PTx is associated with a significant but transient decrease in SBP, DBP and MBP. ptx 9-12 selenium binding protein 1 Homo sapiens 72-75 9249045-1 1997 We have analyzed the secondary structure, shape and dimensions of plasma sex steroid-binding protein (SBP) by CD, size-exclusion chromatography and electron microscopy. Cadmium 110-112 selenium binding protein 1 Homo sapiens 102-105 9249045-11 1997 We propose a model for the structure of SBP in which two monomers assemble head to head with the steroid-binding site located in the center of the rod-like particle. Steroids 97-104 selenium binding protein 1 Homo sapiens 40-43 9169163-11 1997 Also SBP, DBP, and HBP were generally associated with SUA for the whole population sample, with smaller coefficients after excluding those on antihypertensive drugs. sua 54-57 selenium binding protein 1 Homo sapiens 5-8 9158173-11 1997 The SBP is also consistently higher from the low to the high salt intake groups (162.1+/-15.5, 179.3+/-7.4 and 180.8+/-7.6 mmHg, respectively), although the difference is not statistically significant (P>0.1). Salts 61-65 selenium binding protein 1 Homo sapiens 4-7 9107440-9 1997 CONCLUSIONS: When compared with the placebo period, TTS-2 clonidine lowers SBP and DBP within the first 24 hours of application. Clonidine 58-67 selenium binding protein 1 Homo sapiens 75-78 8988947-7 1997 Dietary starch was directly related to SBP and DBP; dietary saturated fatty acid and cholesterol and Keys score were directly related to DBP; dietary magnesium, fiber, and caffeine were inversely related to SBP and DBP; and dietary protein, polyunsaturated fatty acids, the ratio of polyunsaturated to saturated fatty acid, and other simple carbohydrates were inversely related to DBP. Magnesium 150-159 selenium binding protein 1 Homo sapiens 207-210 9065606-2 1997 One of the suggested biological roles of the interaction between SBP and its receptor seems to be a negative control of the E2 induced proliferation of human breast cancer cells through the cAMP pathway. Cyclic AMP 190-194 selenium binding protein 1 Homo sapiens 65-68 8988947-6 1997 Regression analyses confirmed direct independent relations of body mass index, alcohol intake, sodium, and ratio of sodium to potassium to SBP and DBP, and an inverse relation of potassium to SBP and DBP. Sodium 116-122 selenium binding protein 1 Homo sapiens 139-142 8988947-6 1997 Regression analyses confirmed direct independent relations of body mass index, alcohol intake, sodium, and ratio of sodium to potassium to SBP and DBP, and an inverse relation of potassium to SBP and DBP. Potassium 126-135 selenium binding protein 1 Homo sapiens 139-142 8988947-7 1997 Dietary starch was directly related to SBP and DBP; dietary saturated fatty acid and cholesterol and Keys score were directly related to DBP; dietary magnesium, fiber, and caffeine were inversely related to SBP and DBP; and dietary protein, polyunsaturated fatty acids, the ratio of polyunsaturated to saturated fatty acid, and other simple carbohydrates were inversely related to DBP. Caffeine 172-180 selenium binding protein 1 Homo sapiens 207-210 8988947-6 1997 Regression analyses confirmed direct independent relations of body mass index, alcohol intake, sodium, and ratio of sodium to potassium to SBP and DBP, and an inverse relation of potassium to SBP and DBP. Potassium 179-188 selenium binding protein 1 Homo sapiens 192-195 9033699-5 1996 No difference between the groups was demonstrated during the 8 weeks of treatment for the course of blood pressure: SBP and DBP decreased by 20.5 and 13.9 mmHg, respectively, in the rilmenidine group and by 21.3 and 13.1 mmHg in the captopril group (no significant difference: NS). Rilmenidine 182-193 selenium binding protein 1 Homo sapiens 116-119 8988947-7 1997 Dietary starch was directly related to SBP and DBP; dietary saturated fatty acid and cholesterol and Keys score were directly related to DBP; dietary magnesium, fiber, and caffeine were inversely related to SBP and DBP; and dietary protein, polyunsaturated fatty acids, the ratio of polyunsaturated to saturated fatty acid, and other simple carbohydrates were inversely related to DBP. Starch 8-14 selenium binding protein 1 Homo sapiens 39-42 9112062-7 1997 RESULTS: The relationship between nisoldipine plasma concentrations and percentage reduction in BP [diastolic (DBP) and systolic (SBP), supine and standing] could be described by an Emax model. Nisoldipine 34-45 selenium binding protein 1 Homo sapiens 130-133 9086315-5 1996 Sodium loading increased SBP and decreased HR in all high physical activity subjects but not in low physical activity subjects (p < 0.05). Sodium 0-6 selenium binding protein 1 Homo sapiens 25-28 8961085-8 1996 Moclobemide potentiated the effect of ephedrine by a median factor of 3.2 for SBP, 3.8 for DBP, and 0.6 for HR. Moclobemide 0-11 selenium binding protein 1 Homo sapiens 78-81 8976560-0 1996 Direct evidence for the localization of the steroid-binding site of the plasma sex steroid-binding protein (SBP or SHBG) at the interface between the subunits. Steroids 44-51 selenium binding protein 1 Homo sapiens 108-111 8976560-1 1996 Complete dissociation of dimeric plasma sex steroid-binding protein (SBP or SHBG) was obtained in 6 M urea at 10 degrees C. Removal of urea resulted in the refolding of monomers, followed by reformation of dimeric SBP, which migrates with the same mobility as the native protein. Urea 102-106 selenium binding protein 1 Homo sapiens 69-72 8976560-1 1996 Complete dissociation of dimeric plasma sex steroid-binding protein (SBP or SHBG) was obtained in 6 M urea at 10 degrees C. Removal of urea resulted in the refolding of monomers, followed by reformation of dimeric SBP, which migrates with the same mobility as the native protein. Urea 135-139 selenium binding protein 1 Homo sapiens 69-72 8976560-1 1996 Complete dissociation of dimeric plasma sex steroid-binding protein (SBP or SHBG) was obtained in 6 M urea at 10 degrees C. Removal of urea resulted in the refolding of monomers, followed by reformation of dimeric SBP, which migrates with the same mobility as the native protein. Urea 135-139 selenium binding protein 1 Homo sapiens 214-217 8976560-8 1996 Because native monomers do not exist alone, the often-asked question of whether the SBP monomer binds steroid can be considered meaningless; steroid-binding activity is expressed only in the dimeric state. Steroids 102-109 selenium binding protein 1 Homo sapiens 84-87 9086315-8 1996 These data suggest that high physical activity levels do not attenuate but rather exaggerate SBP response to a sodium load. Sodium 111-117 selenium binding protein 1 Homo sapiens 93-96 8769587-10 1996 At 6 months, mean DBP decreased by 13.0 mm Hg in both groups, and mean SBP decreased by 19.5 mm Hg in hydrochlorothiazide and 16.0 mm Hg in isradipine (P=.002); the difference in SBP between the 2 groups persisted throughout the study but did not explain the increased incidence of vascular events in patients treated with isradipine. Hydrochlorothiazide 102-121 selenium binding protein 1 Homo sapiens 71-74 8769587-10 1996 At 6 months, mean DBP decreased by 13.0 mm Hg in both groups, and mean SBP decreased by 19.5 mm Hg in hydrochlorothiazide and 16.0 mm Hg in isradipine (P=.002); the difference in SBP between the 2 groups persisted throughout the study but did not explain the increased incidence of vascular events in patients treated with isradipine. Isradipine 140-150 selenium binding protein 1 Homo sapiens 71-74 8902314-6 1996 After L-DOPS for 4 weeks, BP reduction in the initial phase was significantly attenuated (delta SBP/DBP = -37 +/- 9/-17 +/- 7 mmHg, p < 0.05) and recovery time was normalized in all, although supine BP and HR were unchanged. Droxidopa 6-12 selenium binding protein 1 Homo sapiens 96-99 8953207-6 1996 RESULTS: After correlation for placebo response the mean casual systolic/diastolic BP (SBP/DBP) reduction was 10/5 mm Hg (NS) and 12/10 mm Hg (P < 0.05) for felodipine ER 2.5 and 5 mg, respectively. Felodipine 160-170 selenium binding protein 1 Homo sapiens 87-90 8875085-8 1996 During pretreatment test, L-arginine infusion decreased sBP (from 137 +/- 4.1 to 129 +/- 4.5 mmHg, P < 0.01) and dBP (from 79 +/- 1.9 to 75 +/- 1.2 mmHg, P < 0.01) without affecting heart rate or plasma catecholamines. Arginine 26-36 selenium binding protein 1 Homo sapiens 56-59 8875085-10 1996 After metformin treatment, the decrease in blood pressure after L-arginine infusion was significantly enhanced, with a maximal decrease of sBP of 12 +/- 3.4 mmHg (8 +/- 2.5 mmHg pretreatment, P < 0.05) and dBP of 9.5 +/- 2.4 mmHg (4.5 +/- 1.9 mmHg pretreatment, P < 0.01). Metformin 6-15 selenium binding protein 1 Homo sapiens 139-142 8875085-10 1996 After metformin treatment, the decrease in blood pressure after L-arginine infusion was significantly enhanced, with a maximal decrease of sBP of 12 +/- 3.4 mmHg (8 +/- 2.5 mmHg pretreatment, P < 0.05) and dBP of 9.5 +/- 2.4 mmHg (4.5 +/- 1.9 mmHg pretreatment, P < 0.01). Arginine 64-74 selenium binding protein 1 Homo sapiens 139-142 8856491-4 1996 Lacidipine and amlodipine both significantly reduced systolic blood pressure (SBP: by 19.2 +/- 13.5 and 22.3 +/- 15.3 mm Hg, respectively) and diastolic BP (DBP: 13.3 +/- 4.2 and 12.3 +/- 5.3 mm Hg, respectively) 24 h postdose. lacidipine 0-10 selenium binding protein 1 Homo sapiens 78-81 8856491-4 1996 Lacidipine and amlodipine both significantly reduced systolic blood pressure (SBP: by 19.2 +/- 13.5 and 22.3 +/- 15.3 mm Hg, respectively) and diastolic BP (DBP: 13.3 +/- 4.2 and 12.3 +/- 5.3 mm Hg, respectively) 24 h postdose. Amlodipine 15-25 selenium binding protein 1 Homo sapiens 78-81 8856482-5 1996 After 1-month losartan treatment, systolic and diastolic BP (SBP, DBP) decreased significantly throughout the 210-min recording whereas heart rate (HR) was unchanged. Losartan 14-22 selenium binding protein 1 Homo sapiens 61-64 8797143-8 1996 There was a dose-related decrease in supine and erect systolic and diastolic BP (SBP, DBP) with irbesartan from 10 mg and beyond, with no change in HR. Irbesartan 96-106 selenium binding protein 1 Homo sapiens 81-84 8880565-15 1996 Amlodipine attenuated SBP rises ( > 140 mm Hg) from 62% to 28% (P < 0.001) and DBP ( > 90 mm Hg) from 73% to 46% (P < 0.001). Amlodipine 0-10 selenium binding protein 1 Homo sapiens 22-25 8697482-6 1996 In the control group, dobutamine produced a significant decrease in both end-diastolic and end-systolic volumes, with percent changes from rest to peak of 24 +/- 5% and 29 +/- 5% respectively, and an average increase of 70 +/- 20% in the SBP/ESVI ratio. Dobutamine 22-32 selenium binding protein 1 Homo sapiens 238-241 8651597-0 1996 MCF-7 cell progesterone receptor (PGR) is additionally modulated by sex steroid binding protein (SBP) and its membrane receptor (SBP-R) through cAMP and PKA. Cyclic AMP 144-148 selenium binding protein 1 Homo sapiens 97-100 8651597-0 1996 MCF-7 cell progesterone receptor (PGR) is additionally modulated by sex steroid binding protein (SBP) and its membrane receptor (SBP-R) through cAMP and PKA. Cyclic AMP 144-148 selenium binding protein 1 Homo sapiens 129-132 8860099-4 1996 After saline loading patients treated with HD-CAP showed an increase in SBP, DBP not observed in patients allocated to LD-CAP. Sodium Chloride 6-12 selenium binding protein 1 Homo sapiens 72-75 8723982-4 1996 RESULTS: Systolic and diastolic blood pressure (SBP and DBP, respectively) were positively related to body mass index, abdomen:hip ratio, norepinephrine excretion, and insulin levels in univariate analyses. Norepinephrine 138-152 selenium binding protein 1 Homo sapiens 48-51 8723982-5 1996 The relationship between insulin level and SBP and DBP persisted after adjustment for body mass index, abdomen:hip ratio, norepinephrine, age, smoking, physical activity level, and antihypertensive medication use. Norepinephrine 122-136 selenium binding protein 1 Homo sapiens 25-46 8723982-6 1996 The norepinephrine level was related to SBP and DBP after adjustment for insulin level, age, smoking, physical activity level, and antihypertensive medication use, and these relationships remained marginally significant after further adjustment for body mass index and abdomen:hip ratio. Norepinephrine 4-18 selenium binding protein 1 Homo sapiens 40-43 8666495-5 1996 In the first 5 years of follow-up, a significant inverse relationship was seen between systolic (SBP) and diastolic blood pressure (DBP) and cancer mortality even after adjustment for age, smoking, social class, physical activity, alcohol intake, body mass index, diabetes, pre-existing ischaemic heart disease, use of antihypertensive drugs, cholesterol, heart rate and serum albumin. Alcohols 231-238 selenium binding protein 1 Homo sapiens 97-100 8860111-8 1996 The administration of ibuprofen (400 mg, three times a day for 3 days) was accompanied by a slight but significant increase in SBP, but not in brachial artery compliance or forearm resistances. Ibuprofen 22-31 selenium binding protein 1 Homo sapiens 127-130 8593818-4 1996 The interaction of estradiol with the receptor-bound SBP has been reported to induce a significant accumulation of cAMP in MCF-7 cells; in addition, a negative modulation of estradiol induced proliferation of these cells has been described after treatment with SBP. Estradiol 19-28 selenium binding protein 1 Homo sapiens 53-56 8593818-4 1996 The interaction of estradiol with the receptor-bound SBP has been reported to induce a significant accumulation of cAMP in MCF-7 cells; in addition, a negative modulation of estradiol induced proliferation of these cells has been described after treatment with SBP. Estradiol 19-28 selenium binding protein 1 Homo sapiens 261-264 8593818-4 1996 The interaction of estradiol with the receptor-bound SBP has been reported to induce a significant accumulation of cAMP in MCF-7 cells; in addition, a negative modulation of estradiol induced proliferation of these cells has been described after treatment with SBP. Cyclic AMP 115-119 selenium binding protein 1 Homo sapiens 53-56 8593818-4 1996 The interaction of estradiol with the receptor-bound SBP has been reported to induce a significant accumulation of cAMP in MCF-7 cells; in addition, a negative modulation of estradiol induced proliferation of these cells has been described after treatment with SBP. Estradiol 174-183 selenium binding protein 1 Homo sapiens 53-56 8593818-4 1996 The interaction of estradiol with the receptor-bound SBP has been reported to induce a significant accumulation of cAMP in MCF-7 cells; in addition, a negative modulation of estradiol induced proliferation of these cells has been described after treatment with SBP. Estradiol 174-183 selenium binding protein 1 Homo sapiens 261-264 8593818-5 1996 We report here a more detailed observation about the effect of SBP on MCF-7 cell estradiol-induced growth as well as the possible linkage between SBP and its membrane receptor and protein kinase A activity. Estradiol 81-90 selenium binding protein 1 Homo sapiens 63-66 8593818-6 1996 MCF-7 cell growth was induced by estradiol, but the effect of estradiol was completely abolished by cell treatment with both SBP and estradiol. Estradiol 62-71 selenium binding protein 1 Homo sapiens 125-128 8593818-6 1996 MCF-7 cell growth was induced by estradiol, but the effect of estradiol was completely abolished by cell treatment with both SBP and estradiol. Estradiol 62-71 selenium binding protein 1 Homo sapiens 125-128 8593818-8 1996 Because it was suggested that SBP might act through cAMP, we investigated the effect of SBP and estradiol in cells treated with protein kinase A inhibitor peptide (6-22) amide, a specific inhibitor of the cAMP target protein kinase A. Cyclic AMP 52-56 selenium binding protein 1 Homo sapiens 30-33 8593818-8 1996 Because it was suggested that SBP might act through cAMP, we investigated the effect of SBP and estradiol in cells treated with protein kinase A inhibitor peptide (6-22) amide, a specific inhibitor of the cAMP target protein kinase A. Cyclic AMP 205-209 selenium binding protein 1 Homo sapiens 30-33 8593818-9 1996 The blockade of PKA had no effect on estradiol action on cell growth but masked completely the effect of SBP because MCF-7 increased growth sustained by estradiol was fully detectable also in the presence of SBP. Estradiol 153-162 selenium binding protein 1 Homo sapiens 105-108 8593818-12 1996 The inhibitory effect of 8Br-cAMP on estradiol-induced proliferation was already detectable at analog concentration of 100 nM, which has been reported to be the level reached by cAMP in MCF-7 cells treated with SBP and estradiol. 8-Bromo Cyclic Adenosine Monophosphate 25-33 selenium binding protein 1 Homo sapiens 211-214 8593818-12 1996 The inhibitory effect of 8Br-cAMP on estradiol-induced proliferation was already detectable at analog concentration of 100 nM, which has been reported to be the level reached by cAMP in MCF-7 cells treated with SBP and estradiol. Estradiol 37-46 selenium binding protein 1 Homo sapiens 211-214 8593818-12 1996 The inhibitory effect of 8Br-cAMP on estradiol-induced proliferation was already detectable at analog concentration of 100 nM, which has been reported to be the level reached by cAMP in MCF-7 cells treated with SBP and estradiol. Cyclic AMP 29-33 selenium binding protein 1 Homo sapiens 211-214 8593818-13 1996 In conclusion, the present study strongly confirms our previous observation that SBP inhibits the estradiol induction of MCF-7 cell growth, appropriately suggesting that this SBP action, a consequence of the interaction with the receptor, is likely to be mediated by cAMP and PKA. Estradiol 98-107 selenium binding protein 1 Homo sapiens 81-84 8593818-13 1996 In conclusion, the present study strongly confirms our previous observation that SBP inhibits the estradiol induction of MCF-7 cell growth, appropriately suggesting that this SBP action, a consequence of the interaction with the receptor, is likely to be mediated by cAMP and PKA. Estradiol 98-107 selenium binding protein 1 Homo sapiens 175-178 8593818-13 1996 In conclusion, the present study strongly confirms our previous observation that SBP inhibits the estradiol induction of MCF-7 cell growth, appropriately suggesting that this SBP action, a consequence of the interaction with the receptor, is likely to be mediated by cAMP and PKA. Cyclic AMP 267-271 selenium binding protein 1 Homo sapiens 81-84 8593818-13 1996 In conclusion, the present study strongly confirms our previous observation that SBP inhibits the estradiol induction of MCF-7 cell growth, appropriately suggesting that this SBP action, a consequence of the interaction with the receptor, is likely to be mediated by cAMP and PKA. Cyclic AMP 267-271 selenium binding protein 1 Homo sapiens 175-178 8666495-5 1996 In the first 5 years of follow-up, a significant inverse relationship was seen between systolic (SBP) and diastolic blood pressure (DBP) and cancer mortality even after adjustment for age, smoking, social class, physical activity, alcohol intake, body mass index, diabetes, pre-existing ischaemic heart disease, use of antihypertensive drugs, cholesterol, heart rate and serum albumin. Cholesterol 343-354 selenium binding protein 1 Homo sapiens 97-100 8642191-6 1996 The antihypertensive effect, measured with a mercury sphygmomanometer, was assessed in 64 patients: SBP decreased by 18.6 +/- 12.1 mm Hg in the trandolapril (P < 0.001) and by 21.0 +/- 13.7 mm Hg in the nitrendipine group (P < 0.001); DBP decreased by 13.4 +/- 8.5 mm Hg in the trandolapril group (P < 0.001) and by 15.4 +/-8.2 mm Hg in the nitrendipine group (P < 0.001). trandolapril 144-156 selenium binding protein 1 Homo sapiens 100-103 8973788-7 1996 The trough:peak ratio for both SBP and DBP was higher than 50% for all three manidipine dosage regimens. manidipine 77-87 selenium binding protein 1 Homo sapiens 31-34 8973788-8 1996 The percentage of abnormal ambulatory SBP and DBP readings was significantly reduced in all manidipine-treated groups versus placebo. manidipine 92-102 selenium binding protein 1 Homo sapiens 38-41 8973789-11 1996 Analysis of covariance between doses confirmed a more potent hypotensive effect of manidipine 20 mg as compared to 10 mg on sitting DBP and mean BP and on standing SBP, especially in patients with moderate hypertension. manidipine 83-93 selenium binding protein 1 Homo sapiens 164-167 8964584-3 1996 MCF-7 cells treated with SBP and E2 showed a marked increase of intracellular cAMP, and a significant reduction of both E2 induced cell proliferation and E2-mediated increase of progesterone receptor (PGR). Cyclic AMP 78-82 selenium binding protein 1 Homo sapiens 25-28 8594308-1 1996 The interactions of human Sex steroid binding protein (SBP) and the lignans [Nordihydrogaiaretic acid (NDGA) enterolactone (Ent), enterodiol (End)] and isoflavonoid phytoestrogens [Equol (Eq), diazein Dad), genistein (Gen)] were studied. nordihydrogaiaretic acid (ndga) enterolactone 77-122 selenium binding protein 1 Homo sapiens 55-58 8594308-1 1996 The interactions of human Sex steroid binding protein (SBP) and the lignans [Nordihydrogaiaretic acid (NDGA) enterolactone (Ent), enterodiol (End)] and isoflavonoid phytoestrogens [Equol (Eq), diazein Dad), genistein (Gen)] were studied. 2,3-bis(3'-hydroxybenzyl)butane-1,4-diol 130-140 selenium binding protein 1 Homo sapiens 55-58 8594308-1 1996 The interactions of human Sex steroid binding protein (SBP) and the lignans [Nordihydrogaiaretic acid (NDGA) enterolactone (Ent), enterodiol (End)] and isoflavonoid phytoestrogens [Equol (Eq), diazein Dad), genistein (Gen)] were studied. isoflavonoid 152-164 selenium binding protein 1 Homo sapiens 55-58 8594308-1 1996 The interactions of human Sex steroid binding protein (SBP) and the lignans [Nordihydrogaiaretic acid (NDGA) enterolactone (Ent), enterodiol (End)] and isoflavonoid phytoestrogens [Equol (Eq), diazein Dad), genistein (Gen)] were studied. Equol 181-186 selenium binding protein 1 Homo sapiens 55-58 8594308-1 1996 The interactions of human Sex steroid binding protein (SBP) and the lignans [Nordihydrogaiaretic acid (NDGA) enterolactone (Ent), enterodiol (End)] and isoflavonoid phytoestrogens [Equol (Eq), diazein Dad), genistein (Gen)] were studied. Equol 181-183 selenium binding protein 1 Homo sapiens 55-58 8594308-1 1996 The interactions of human Sex steroid binding protein (SBP) and the lignans [Nordihydrogaiaretic acid (NDGA) enterolactone (Ent), enterodiol (End)] and isoflavonoid phytoestrogens [Equol (Eq), diazein Dad), genistein (Gen)] were studied. diazein dad 193-204 selenium binding protein 1 Homo sapiens 55-58 8594308-1 1996 The interactions of human Sex steroid binding protein (SBP) and the lignans [Nordihydrogaiaretic acid (NDGA) enterolactone (Ent), enterodiol (End)] and isoflavonoid phytoestrogens [Equol (Eq), diazein Dad), genistein (Gen)] were studied. Genistein 207-216 selenium binding protein 1 Homo sapiens 55-58 8594308-2 1996 The phytoestrogens had different dose-dependent inhibitory effects on steroid binding by SBP. Steroids 70-77 selenium binding protein 1 Homo sapiens 89-92 8594308-8 1996 Our results indicate that phytoestrogens may modulate the SBP activity and so influence the role of this protein in the delivery of hormonal information to sex steroid-dependent cells. Steroids 160-167 selenium binding protein 1 Homo sapiens 58-61 8642191-9 1996 Mean 24 h ambulatory SBP/DBP decreases were 6.6 +/- 18.0/8.4 +/- 8.5 mm Hg in the trandolapril group (P < 0.001) and 5.7 +/- 11.1/7.2 +/-9.6 mm Hg in the nitrendipine group (P < 0.001). trandolapril 82-94 selenium binding protein 1 Homo sapiens 21-24 8642191-11 1996 The antihypertensive action of trandolapril was sustained throughout the 24 h period with a trough-to-peak ratio of 70.2% for SBP and 70.9% for DBP. trandolapril 31-43 selenium binding protein 1 Homo sapiens 126-129 8642191-12 1996 Nitrendipine exerted its action mainly during the day, with a very modest antihypertensive effect during the night and early morning; its trough/peak ratio was 25.9% for SBP and 28% for DBP. Nitrendipine 0-12 selenium binding protein 1 Homo sapiens 170-173 8562197-8 1995 Third-generation cephalosporins commonly used in the therapy of SBP, are ineffective in this infection. Cephalosporins 17-31 selenium binding protein 1 Homo sapiens 64-67 8576898-8 1995 In examining the factors associated with the awake-sleep change in pressure, the most important predictors were a low sleep pressure and alcohol intake, both of which were associated with bigger diurnal changes of both SBP and DBP in both men and women. Alcohols 137-144 selenium binding protein 1 Homo sapiens 219-222 8746604-6 1995 At the end of cilazapril and hydrochlorothiazide administration significant decreases (p < 0.001) in SBP, DBP and MBP vs baseline values were observed. Cilazapril 14-24 selenium binding protein 1 Homo sapiens 104-107 8746604-6 1995 At the end of cilazapril and hydrochlorothiazide administration significant decreases (p < 0.001) in SBP, DBP and MBP vs baseline values were observed. Hydrochlorothiazide 29-48 selenium binding protein 1 Homo sapiens 104-107 8583478-8 1995 Compared with placebo, which had no effect, all three losartan regimens decreased SBP and DBP significantly. Losartan 54-62 selenium binding protein 1 Homo sapiens 82-85 8554929-7 1995 Oscillometry yielded good approximations for the SBP response to isoprenaline (average method difference SBPo-SBPg: -2.9, 95% CI: -9.0 to 3.3 mm Hg, REP: 17.6 mm Hg) but was poorly sensitive with regard to the DBP responses: method difference DBPo-DBPg: 6.5, 95% CI: -1.3 to 14.3 mm Hg, REP: 25.7 mm Hg. Isoproterenol 65-77 selenium binding protein 1 Homo sapiens 49-52 8745662-9 1995 In the pure systolic HT subgroup treated by trandolapril monotherapy, the antihypertensive effect predominantly affected the SBP (-23 +/- 12/- 4 +/- 6 mmHg). trandolapril 44-56 selenium binding protein 1 Homo sapiens 125-128 8745614-8 1995 The reductions in SBP measured in the morning and evening and in DBP measured in the morning were significantly greater in the group with low RA than in the group with high RA. Radium 142-144 selenium binding protein 1 Homo sapiens 18-21 8745614-8 1995 The reductions in SBP measured in the morning and evening and in DBP measured in the morning were significantly greater in the group with low RA than in the group with high RA. Radium 173-175 selenium binding protein 1 Homo sapiens 18-21 7621441-1 1995 Compounds formed by 5-nitrofuran with hydrazides of formic, acetic and propionic acids, hereafter respectively known as SBF, SBA and SBP have been used to evaluate the differentiation-inducing properties on two established myeloid leukaemic cell lines ML-2 and EOL-1. Nitrofurans 20-32 selenium binding protein 1 Homo sapiens 133-136 7499729-5 1995 MSNA (bursts/min), heart rate (HR), and systolic and diastolic blood pressures (dBP and sBP) were significantly increased at 2-3 min after glucagon injection. Glucagon 139-147 selenium binding protein 1 Homo sapiens 88-91 8523374-8 1995 The fall in ambulatory SBP was significantly greater (P < 0.001) in the patients treated with amlodipine compared with felodipine ER whereas there was no difference between the groups with respect to ambulatory DBP. Amlodipine 97-107 selenium binding protein 1 Homo sapiens 23-26 8523374-8 1995 The fall in ambulatory SBP was significantly greater (P < 0.001) in the patients treated with amlodipine compared with felodipine ER whereas there was no difference between the groups with respect to ambulatory DBP. Felodipine 122-132 selenium binding protein 1 Homo sapiens 23-26 7621441-1 1995 Compounds formed by 5-nitrofuran with hydrazides of formic, acetic and propionic acids, hereafter respectively known as SBF, SBA and SBP have been used to evaluate the differentiation-inducing properties on two established myeloid leukaemic cell lines ML-2 and EOL-1. formic 52-58 selenium binding protein 1 Homo sapiens 133-136 7621441-3 1995 Induction of differentiation observed are in the order SBP > SBA > SBF, as assessed by morphology, NBT-reducing activity and surface marker antigens of the treated cells. Nitroblue Tetrazolium 105-108 selenium binding protein 1 Homo sapiens 55-58 7482386-4 1995 The evolution of the SBP/heart rate slope was significantly different among the two active groups in favour of the BZ 10 regimen. Quinuclidinyl Benzilate 115-117 selenium binding protein 1 Homo sapiens 21-24 7496561-9 1995 Nicergoline had no significant effect on HR but significantly decreased SBP (117.8 +/- 1.4 mmHg vs 127 +/- 1.6 with placebo, p < 0.001). Nicergoline 0-11 selenium binding protein 1 Homo sapiens 72-75 7564352-9 1995 Twenty four-hour ambulatory SBP and DBP decreased from 148 +/- 14/92 +/- 10 mm Hg to 135 +/- 14/83 +/- 10 mm Hg in the trandolapril group (p < 0.001). trandolapril 119-131 selenium binding protein 1 Homo sapiens 28-31 7595908-3 1995 In study 1, low-dose verapamil significantly reduced office and ambulatory diastolic (DBP) and systolic (SBP) blood pressure (P < 0.01) in patients with mild hypertension. Verapamil 21-30 selenium binding protein 1 Homo sapiens 105-108 7594444-8 1995 With sinorphan only a significant decrease in night-time SBP was found. racecadotril 5-14 selenium binding protein 1 Homo sapiens 57-60 7594444-9 1995 With the combined therapy of sinorphan and captopril, significant decreases both in SBP and in DBP were observed, which were sustained over 24 h. After 4 weeks of sinorphan alone or in combination with captopril, no change in plasma atrial natriuretic peptide level was found. racecadotril 29-38 selenium binding protein 1 Homo sapiens 84-87 7594444-9 1995 With the combined therapy of sinorphan and captopril, significant decreases both in SBP and in DBP were observed, which were sustained over 24 h. After 4 weeks of sinorphan alone or in combination with captopril, no change in plasma atrial natriuretic peptide level was found. Captopril 43-52 selenium binding protein 1 Homo sapiens 84-87 7632029-13 1995 The [double product (SBP x HR)/load (in watts)] ratio at the ischaemic threshold of 1 mm reached at M0, decreased significantly in the trimetazidine group by 69.9 (p < 0.001) versus 20.3 in the placebo group (NS). Trimetazidine 135-148 selenium binding protein 1 Homo sapiens 21-24 7586999-6 1995 10 minutes after sumatriptan administration a significant increase (p > 0.001) both in SBP and BDP was observed. Sumatriptan 17-28 selenium binding protein 1 Homo sapiens 90-93 7662600-5 1995 After a 20 mg single oral dose, blood pressure decreased significantly more with ISDN (SBP: 6%; DBP: 14%) than with N (SBP: 2%; DBP: 6%), but after 8 days this decrease in blood pressure was not statistically different between ISDN and N. The diameter of CCA increased more with ISDN (11%) than N (5%) acutely as well as subacutely (ISDN: 12%; N: 9%). Nicorandil 84-85 selenium binding protein 1 Homo sapiens 87-90 7595908-4 1995 In study 2, verapamil and nifedipine significantly and similarly reduced office DBP and SBP in patients with mild to moderate hypertension. Verapamil 12-21 selenium binding protein 1 Homo sapiens 88-91 7595908-4 1995 In study 2, verapamil and nifedipine significantly and similarly reduced office DBP and SBP in patients with mild to moderate hypertension. Nifedipine 26-36 selenium binding protein 1 Homo sapiens 88-91 7595908-5 1995 In study 3, significantly greater reductions in ambulatory DBP and SBP were observed with verapamil compared with placebo (P < 0.01) in elderly patients with mild to moderate hypertension. Verapamil 90-99 selenium binding protein 1 Homo sapiens 67-70 7843777-5 1995 delta SBP was markedly suppressed by the administration of both propranolol and prazosin. Propranolol 64-75 selenium binding protein 1 Homo sapiens 6-9 7644088-6 1995 In fact, at the end of the treatment with ketanserin, supine SBP was decreased 10 +/- 20 and DBP 5 +/- 10 mmHg, standing SBP was reduced 15 +/- 19 and DBP 7 +/- 15 mmHg. Ketanserin 42-52 selenium binding protein 1 Homo sapiens 61-64 7644088-6 1995 In fact, at the end of the treatment with ketanserin, supine SBP was decreased 10 +/- 20 and DBP 5 +/- 10 mmHg, standing SBP was reduced 15 +/- 19 and DBP 7 +/- 15 mmHg. Ketanserin 42-52 selenium binding protein 1 Homo sapiens 121-124 7644088-7 1995 With enalapril supine SBP decreased 25 +/- 16 and DBP 10 +/- 13 mmHg, standing SBP was reduced 16 +/- 19 and DBP 8 +/- 18 mmHg. Enalapril 5-14 selenium binding protein 1 Homo sapiens 22-25 7864425-10 1995 SBP values were lower after labetalol 10 min after the seizure, but not after esmolol. Labetalol 28-37 selenium binding protein 1 Homo sapiens 0-3 7843777-5 1995 delta SBP was markedly suppressed by the administration of both propranolol and prazosin. Prazosin 80-88 selenium binding protein 1 Homo sapiens 6-9 7753427-5 1994 Nifedipine reduced SBP and DBP by respectively 6.5% and 13.1% at 8 am and 5.3% and 9.4% at 8 pm. Nifedipine 0-10 selenium binding protein 1 Homo sapiens 19-22 10150320-4 1995 Single-dose ramipril reduced both SBP and DBP (P < .001) without affecting heart rate. Ramipril 12-20 selenium binding protein 1 Homo sapiens 34-37 10150320-6 1995 Cosinor analysis demonstrated that both administrations of ramipril effectively lowered SBP and DBP mesors (P < .001), compared to placebo; circadian rhythms remained undisturbed. Ramipril 59-67 selenium binding protein 1 Homo sapiens 88-91 7818152-4 1995 The average twenty-four-hour systolic and diastolic BPs (SBP and DBP) were lowered by doxazosin treatment and returned to the pretreatment levels within two days of doxazosin withdrawal. Doxazosin 86-95 selenium binding protein 1 Homo sapiens 57-60 7818152-5 1995 Doxazosin treatment produced a significant decrease in the daytime SBP and DBP but not in the nighttime BP values. Doxazosin 0-9 selenium binding protein 1 Homo sapiens 67-70 7752176-3 1995 Nifedipine and furosemide reduced blood pressure to the same extent (-14 to -15 mm Hg for supine SBP and -9 to -10 mm Hg for supine DBP, both P < 0.0001). Nifedipine 0-10 selenium binding protein 1 Homo sapiens 97-100 7752176-3 1995 Nifedipine and furosemide reduced blood pressure to the same extent (-14 to -15 mm Hg for supine SBP and -9 to -10 mm Hg for supine DBP, both P < 0.0001). Furosemide 15-25 selenium binding protein 1 Homo sapiens 97-100 7701543-0 1994 The receptor-mediated action of sex steroid binding protein (SBP, SHBG): accumulation of cAMP in MCF-7 cells under SBP and estradiol treatment. Cyclic AMP 89-93 selenium binding protein 1 Homo sapiens 61-64 7963274-11 1994 However, the elevation in systolic blood pressure (delta SBP) and mean blood pressure (delta MBP) from basal levels in response to a given dose of phenylephrine were significantly larger (delta SBP:18 +/- 3 vs 26 +/- 3 mmHg, p < .01; and delta MBP 10 +/- 2 vs 15 +/- 3 mmHg, p < .01) after than before training. Phenylephrine 147-160 selenium binding protein 1 Homo sapiens 57-60 7963274-11 1994 However, the elevation in systolic blood pressure (delta SBP) and mean blood pressure (delta MBP) from basal levels in response to a given dose of phenylephrine were significantly larger (delta SBP:18 +/- 3 vs 26 +/- 3 mmHg, p < .01; and delta MBP 10 +/- 2 vs 15 +/- 3 mmHg, p < .01) after than before training. Phenylephrine 147-160 selenium binding protein 1 Homo sapiens 194-197 7701543-0 1994 The receptor-mediated action of sex steroid binding protein (SBP, SHBG): accumulation of cAMP in MCF-7 cells under SBP and estradiol treatment. Cyclic AMP 89-93 selenium binding protein 1 Homo sapiens 115-118 7701543-0 1994 The receptor-mediated action of sex steroid binding protein (SBP, SHBG): accumulation of cAMP in MCF-7 cells under SBP and estradiol treatment. Estradiol 123-132 selenium binding protein 1 Homo sapiens 61-64 7701543-1 1994 The interaction of sex steroid binding protein (SBP) with its specific receptor in MCF-7 cell (estrogen-sensitive human breast cancer cells), followed by the binding of estradiol (E2) to the complex SBP-receptor, induced a significant accumulation of intracellular cAMP. Estradiol 169-178 selenium binding protein 1 Homo sapiens 48-51 7701543-1 1994 The interaction of sex steroid binding protein (SBP) with its specific receptor in MCF-7 cell (estrogen-sensitive human breast cancer cells), followed by the binding of estradiol (E2) to the complex SBP-receptor, induced a significant accumulation of intracellular cAMP. Estradiol 169-178 selenium binding protein 1 Homo sapiens 199-202 7701543-1 1994 The interaction of sex steroid binding protein (SBP) with its specific receptor in MCF-7 cell (estrogen-sensitive human breast cancer cells), followed by the binding of estradiol (E2) to the complex SBP-receptor, induced a significant accumulation of intracellular cAMP. Cyclic AMP 265-269 selenium binding protein 1 Homo sapiens 48-51 7701543-1 1994 The interaction of sex steroid binding protein (SBP) with its specific receptor in MCF-7 cell (estrogen-sensitive human breast cancer cells), followed by the binding of estradiol (E2) to the complex SBP-receptor, induced a significant accumulation of intracellular cAMP. Cyclic AMP 265-269 selenium binding protein 1 Homo sapiens 199-202 7701543-3 1994 The maximal increase in cAMP was observed with 1 nM SBP + 1 nM E2. Cyclic AMP 24-28 selenium binding protein 1 Homo sapiens 52-55 7701543-8 1994 In summary, the present study provides evidence that the SBP receptor is part of the G-protein receptor family, and that SBP can act as modulator of E2 action at cell site through the second messenger cAMP. Cyclic AMP 201-205 selenium binding protein 1 Homo sapiens 57-60 7701543-8 1994 In summary, the present study provides evidence that the SBP receptor is part of the G-protein receptor family, and that SBP can act as modulator of E2 action at cell site through the second messenger cAMP. Cyclic AMP 201-205 selenium binding protein 1 Homo sapiens 121-124 7852756-6 1994 SBP and DBP were significantly and independently related to age, body mass index, heart rate, use of antihypertensive drugs, serum triglycerides level, alcohol use (males only) and inversely to cigarette smoking. Triglycerides 131-144 selenium binding protein 1 Homo sapiens 0-3 7878638-11 1994 infusion of Mch and SNP increased forearm blood flow from 1.9 to 14.9 and from 1.8 to 12.1 ml x min-1 x 100 ml-1, respectively (Mch vs SBP N.S.). Methacholine Chloride 12-15 selenium binding protein 1 Homo sapiens 135-138 7528305-5 1994 SBP and DBP responses to Ang I were also strongly related to temocapril diacid concentration (r = -0.81 and r = -0.88, n = 148). temocaprilat 61-78 selenium binding protein 1 Homo sapiens 0-3 7852756-6 1994 SBP and DBP were significantly and independently related to age, body mass index, heart rate, use of antihypertensive drugs, serum triglycerides level, alcohol use (males only) and inversely to cigarette smoking. Alcohols 152-159 selenium binding protein 1 Homo sapiens 0-3 7980944-2 1994 Binding data obtained using charcoal adsorption assay and equilibrium dialysis methods indicates a single protein, named Bufo arenarum sex binding protein (Ba SBP), which binds 5 alpha-dihydrotestosterone (DHT), testosterone (T), and estradiol-17 beta (E2) with high affinity (10(-7) M-1 - 10(8) M-1) and fair capacity (10(-6) M). alpha-dihydrotestosterone 179-204 selenium binding protein 1 Homo sapiens 159-162 11835076-4 1994 Mean supine SBP/DBP reductions from baseline for all HCTZ plus perindopril groups were significantly (p less-than-or-equal 0.05) greater than for HCTZ plus placebo. Hydrochlorothiazide 53-57 selenium binding protein 1 Homo sapiens 12-15 11835076-4 1994 Mean supine SBP/DBP reductions from baseline for all HCTZ plus perindopril groups were significantly (p less-than-or-equal 0.05) greater than for HCTZ plus placebo. Perindopril 63-74 selenium binding protein 1 Homo sapiens 12-15 11835076-6 1994 At the final visit, mean reductions in supine SBP/DBP were 10.3/6.7, 9.6/8.0, and 9.3/6.3 mmHg for HCTZ plus perindopril 2, 4, and 8 mg, respectively, and 1.6/2.0 mmHg for HCTZ plus placebo. Hydrochlorothiazide 99-103 selenium binding protein 1 Homo sapiens 46-49 7986458-5 1994 A P10 to P90 (10th and 90th percentile) increase of alcohol intake, as reflected by serum gamma-glutamyltransferase, was associated with a 3.2 +/- 0.9 mm Hg higher DBP in men and with a 3.1 +/- 1.6 mm Hg higher SBP and a 1.5 +/- 0.8 mm Hg higher DBP in women. Alcohols 52-59 selenium binding protein 1 Homo sapiens 211-214 7980944-2 1994 Binding data obtained using charcoal adsorption assay and equilibrium dialysis methods indicates a single protein, named Bufo arenarum sex binding protein (Ba SBP), which binds 5 alpha-dihydrotestosterone (DHT), testosterone (T), and estradiol-17 beta (E2) with high affinity (10(-7) M-1 - 10(8) M-1) and fair capacity (10(-6) M). Dihydrotestosterone 206-209 selenium binding protein 1 Homo sapiens 159-162 7980944-2 1994 Binding data obtained using charcoal adsorption assay and equilibrium dialysis methods indicates a single protein, named Bufo arenarum sex binding protein (Ba SBP), which binds 5 alpha-dihydrotestosterone (DHT), testosterone (T), and estradiol-17 beta (E2) with high affinity (10(-7) M-1 - 10(8) M-1) and fair capacity (10(-6) M). Testosterone 192-204 selenium binding protein 1 Homo sapiens 159-162 7980944-4 1994 Ba SBP has a sedimentation coefficient of 5.2 S in sucrose gradient centrifugation in low salt and under steady-state conditions. Sucrose 51-58 selenium binding protein 1 Homo sapiens 3-6 7980944-4 1994 Ba SBP has a sedimentation coefficient of 5.2 S in sucrose gradient centrifugation in low salt and under steady-state conditions. Salts 90-94 selenium binding protein 1 Homo sapiens 3-6 8089195-3 1994 It is shown that CeReS-18 mediated cell cycle arrest of both human diploid fibroblasts (HSBP) and mouse fibroblasts (Swiss 3T3) results in the maintenance of the RB protein in the hypophosphorylated state, consistent with a late G1 arrest site. ceres-18 17-25 selenium binding protein 1 Homo sapiens 88-92 7990088-4 1994 In INTERSALT, across centres, average sodium excretion was significantly related to slope of BP with age, such that 100 mmol lower sodium was associated with 10 mmHg lower rise in SBP over 30 years; among individuals, previous estimates of the size of relationships of sodium and potassium to BP in INTERSALT were too low because of insufficient correction for the "regression dilution" problem. Sodium 131-137 selenium binding protein 1 Homo sapiens 180-183 7990088-4 1994 In INTERSALT, across centres, average sodium excretion was significantly related to slope of BP with age, such that 100 mmol lower sodium was associated with 10 mmHg lower rise in SBP over 30 years; among individuals, previous estimates of the size of relationships of sodium and potassium to BP in INTERSALT were too low because of insufficient correction for the "regression dilution" problem. Sodium 131-137 selenium binding protein 1 Homo sapiens 180-183 7990088-5 1994 For sodium, revised corrected regression estimates, with adjustment for age and sex, were 4.3 mmHg/100 mmol for SBP and 1.8 mmHg/100 mmol for DBP. Sodium 4-10 selenium binding protein 1 Homo sapiens 112-115 11835069-3 1994 Twenty-five hours after dose the mean supine SBP/DBP on metoprolol CR 50 mg was 147/95 mm Hg and on conventional metoprolol 100 mg 148/94 mm Hg, respectively. metoprolol cr 56-69 selenium binding protein 1 Homo sapiens 45-48 11835069-3 1994 Twenty-five hours after dose the mean supine SBP/DBP on metoprolol CR 50 mg was 147/95 mm Hg and on conventional metoprolol 100 mg 148/94 mm Hg, respectively. Metoprolol 56-66 selenium binding protein 1 Homo sapiens 45-48 8089833-4 1994 Fosinopril decreased average 24h SBP and DBP (-13.5 mmHg and -9.7 mmHg, respectively, P < 0.002); a significant BP reduction was observed both in day and in nighttime, without alteration in diurnal BP profile. Fosinopril 0-10 selenium binding protein 1 Homo sapiens 33-36 8089250-8 1994 Systolic arterial pressure (SBP) increased when subjects stood after saline, but decreased if subjects were HYPO or EU (P < .05 for 1.07% versus HYPO and EU). Sodium Chloride 69-75 selenium binding protein 1 Homo sapiens 28-31 7523776-4 1994 Perindopril caused a significant reduction in mean resting systolic and diastolic blood pressure (SBP, DBP) without increasing resting heart rate (HR); 15-min post-exercise SBP was also significantly reduced. Perindopril 0-11 selenium binding protein 1 Homo sapiens 98-101 8064783-6 1994 There was also a correlation between triglycerides and mean Dinamap SBP (P < 0.01) which could suggest an early insulin resistance. Triglycerides 37-50 selenium binding protein 1 Homo sapiens 68-71 7869010-2 1994 It was revealed that ascitic fluid PMN count if over 500 per mm3, the increased lactate, or decreased glucose level, strongly supported the diagnosis of SBP. Lactic Acid 80-87 selenium binding protein 1 Homo sapiens 153-156 7869010-2 1994 It was revealed that ascitic fluid PMN count if over 500 per mm3, the increased lactate, or decreased glucose level, strongly supported the diagnosis of SBP. Glucose 102-109 selenium binding protein 1 Homo sapiens 153-156 8089250-13 1994 The results for SBP indicate that 1.07% saline may have advantages over 0.9% saline as a countermeasure to postspace-flight or postbedrest orthostatic intolerance. Sodium Chloride 40-46 selenium binding protein 1 Homo sapiens 16-19 8157642-7 1994 This hsp70.hsp90 complex-forming factor is heat-labile, and in the presence of this factor and ATP, a heat shock protein heterocomplex can be reconstituted from purified mouse hsp90 and hsp70 and rabbit hsp56 that is present in the factor preparation. Adenosine Triphosphate 95-98 selenium binding protein 1 Homo sapiens 203-208 7918140-5 1994 Open-label quinapril treatment resulted in significant decreases in mean systolic (SBP) and diastolic (DBP) blood pressure. Quinapril 11-20 selenium binding protein 1 Homo sapiens 83-86 8006921-9 1994 This study showed a significant relationship between categories of alcohol use and SBP and DBP (P < 0.05, respectively) controlled for age and body mass index. Alcohols 67-74 selenium binding protein 1 Homo sapiens 83-86 8021908-2 1994 Therapeutic efficacy of nifedipine was confirmed in 69% of the patients and resulted in reduction of SBP by 20.9% and DBP by 19.0% of their initial values, from 179.7/101.3 to 142.1/82.9 mmHg (p < 0.001). Nifedipine 24-34 selenium binding protein 1 Homo sapiens 101-104 7931253-3 1994 Sensitivity to orally administered tyramine was determined under fasting conditions before and after drug administration and the doses of tyramine yielding a 30 mmHg increase of SBP (PD30) compared. Tyramine 138-146 selenium binding protein 1 Homo sapiens 178-181 8029126-8 1994 Nifedipine caused a significant fall in SBP and DBP (p < 0.001) and a marked increase in HR (p < 0.001). Nifedipine 0-10 selenium binding protein 1 Homo sapiens 40-43 8207740-7 1994 At the end of this trial, there was a significant decrease in both SBP and DBP in the cilazapril group (155 +/- 14 to 142 +/- 12 mmHg systolic, P < 0.01; 106 +/- 6 to 95 +/- 5 mmHg diastolic, P < 0.01). Cilazapril 86-96 selenium binding protein 1 Homo sapiens 67-70 8207740-8 1994 In the nifedipine group, there was also a significant decrease in SBP and DBP (161 +/- 18 to 139 +/- 5 mmHg, systolic, P < 0.01; 101 +/- 6 to 88 +/- 9 mmHg diastolic, P < 0.05) but with a significant increase in heart rate (79 +/- 14 to 91 +/- 10 beats/minute, P < 0.05). Nifedipine 7-17 selenium binding protein 1 Homo sapiens 66-69 8207745-3 1994 The logistic regression procedure was used to calculate the adjusted relative risk of having an elevated SBP by controlling for age, weight and cholesterol. Cholesterol 144-155 selenium binding protein 1 Homo sapiens 105-108 7817355-6 1994 The average 24-hour systolic (SBP) and diastolic (DBP) blood pressure were significantly decreased by trandolapril. trandolapril 102-114 selenium binding protein 1 Homo sapiens 30-33 8207737-6 1994 SBP during surgery was found to be related to the in vitro measured [Ca2+]i in the parathyroid cells at 3.0 mM extracellular calcium concentration or to the ratio of [Ca2+]i at 3.0 mM-0.5 mM (r = -0.25 and -0.27, respectively; P < 0.05). Calcium 125-132 selenium binding protein 1 Homo sapiens 0-3 8005619-3 1993 Treatment of SBP with serotonin (1 microM) and 3-[(3-cholamidopropyl) dimethyl ammonio]-1-propanesulphonate (CHAPS) (2%) solubilized the ligand-receptor-G protein-ligand complex along with the associated phospholipids and cholesterol. Serotonin 22-31 selenium binding protein 1 Homo sapiens 13-16 8117053-4 1993 L/HCTZ and C/HCTZ significantly lowered SBP and DBP on occasional recordings and on ABPM. Hydrochlorothiazide 2-6 selenium binding protein 1 Homo sapiens 40-43 8117053-5 1993 The mean fall in blood pressure on ABPM (SBP, DBP, mean of 24-hour recording, diurnal and nocturnal) at 4 weeks was greater with L/HCTZ than with C/HCTZ. l/ 129-131 selenium binding protein 1 Homo sapiens 41-44 8117053-5 1993 The mean fall in blood pressure on ABPM (SBP, DBP, mean of 24-hour recording, diurnal and nocturnal) at 4 weeks was greater with L/HCTZ than with C/HCTZ. Hydrochlorothiazide 131-135 selenium binding protein 1 Homo sapiens 41-44 8117053-5 1993 The mean fall in blood pressure on ABPM (SBP, DBP, mean of 24-hour recording, diurnal and nocturnal) at 4 weeks was greater with L/HCTZ than with C/HCTZ. Carbon 132-133 selenium binding protein 1 Homo sapiens 41-44 8005619-3 1993 Treatment of SBP with serotonin (1 microM) and 3-[(3-cholamidopropyl) dimethyl ammonio]-1-propanesulphonate (CHAPS) (2%) solubilized the ligand-receptor-G protein-ligand complex along with the associated phospholipids and cholesterol. 3-((3-cholamidopropyl)dimethylammonium)-1-propanesulfonate 47-107 selenium binding protein 1 Homo sapiens 13-16 8005619-3 1993 Treatment of SBP with serotonin (1 microM) and 3-[(3-cholamidopropyl) dimethyl ammonio]-1-propanesulphonate (CHAPS) (2%) solubilized the ligand-receptor-G protein-ligand complex along with the associated phospholipids and cholesterol. 3-((3-cholamidopropyl)dimethylammonium)-1-propanesulfonate 109-114 selenium binding protein 1 Homo sapiens 13-16 8005619-3 1993 Treatment of SBP with serotonin (1 microM) and 3-[(3-cholamidopropyl) dimethyl ammonio]-1-propanesulphonate (CHAPS) (2%) solubilized the ligand-receptor-G protein-ligand complex along with the associated phospholipids and cholesterol. Phospholipids 204-217 selenium binding protein 1 Homo sapiens 13-16 8005619-3 1993 Treatment of SBP with serotonin (1 microM) and 3-[(3-cholamidopropyl) dimethyl ammonio]-1-propanesulphonate (CHAPS) (2%) solubilized the ligand-receptor-G protein-ligand complex along with the associated phospholipids and cholesterol. Cholesterol 222-233 selenium binding protein 1 Homo sapiens 13-16 8247917-7 1993 MEASUREMENTS AND MAIN RESULTS: Combination therapy with DTZ SR-HCTZ lowered both supine DBP and SBP significantly (p < 0.005) more than either single agent. dtz sr-hctz 56-67 selenium binding protein 1 Homo sapiens 96-99 8403905-3 1993 Regression analyses showed that PRL levels were independent of the other parameters, while a negative correlation was found between DHEA-S and SBP values. Dehydroepiandrosterone Sulfate 132-138 selenium binding protein 1 Homo sapiens 143-146 8129524-8 1993 During the stress session, SBP in NT increased from 119.8 to 123.7 mmHg (p < 0.001) and in HT from 147.4 to 152 mmHg (p < 0.05): there was no significant difference between the two samples but in HT, SBP elevation persisted after the stress session, contrary to the NT, whose SBP quickly decreased to the reference values. nt 34-36 selenium binding protein 1 Homo sapiens 27-30 7692173-4 1993 As compared with placebo, isradipine RF decreased daytime BP by 10 mm Hg systolic (SBP, p < 0.001) and by 6 mm Hg diastolic (DBP, p < 0.01), and night SBP and DBP by 7 (p < 0.05) and 3 mm Hg (P = NS), respectively. Isradipine 26-36 selenium binding protein 1 Homo sapiens 83-86 7692173-4 1993 As compared with placebo, isradipine RF decreased daytime BP by 10 mm Hg systolic (SBP, p < 0.001) and by 6 mm Hg diastolic (DBP, p < 0.01), and night SBP and DBP by 7 (p < 0.05) and 3 mm Hg (P = NS), respectively. Isradipine 26-36 selenium binding protein 1 Homo sapiens 157-160 7692173-5 1993 Isradipine MR reduced the daytime SBP 8 mm Hg (p < 0.05) and DBP by 3 mm Hg (p = NS), and the night SBP by 1 mm Hg (p = NS) and DBP by < 1 mm Hg (P = NS). Isradipine 0-10 selenium binding protein 1 Homo sapiens 34-37 7692173-5 1993 Isradipine MR reduced the daytime SBP 8 mm Hg (p < 0.05) and DBP by 3 mm Hg (p = NS), and the night SBP by 1 mm Hg (p = NS) and DBP by < 1 mm Hg (P = NS). Isradipine 0-10 selenium binding protein 1 Homo sapiens 103-106 8410927-11 1993 If anything, amlodipine tended to be slightly more effective at least on supine SBP (155.2/90.9 +/- 4.6/1.7 vs. 147.6/89.1 +2- 4.3/1.8 mmHg; P < 0.05, NS). Amlodipine 13-23 selenium binding protein 1 Homo sapiens 80-83 8403905-5 1993 Clinical improvement was observed in subjects treated with ethynylestradiol plus desogestrel or plus cyproterone acetate, so as to produce an increase in SBP rather than a decrease in DHEA-S. Ethinyl Estradiol 59-75 selenium binding protein 1 Homo sapiens 154-157 8403905-5 1993 Clinical improvement was observed in subjects treated with ethynylestradiol plus desogestrel or plus cyproterone acetate, so as to produce an increase in SBP rather than a decrease in DHEA-S. Desogestrel 81-92 selenium binding protein 1 Homo sapiens 154-157 8403905-5 1993 Clinical improvement was observed in subjects treated with ethynylestradiol plus desogestrel or plus cyproterone acetate, so as to produce an increase in SBP rather than a decrease in DHEA-S. Cyproterone Acetate 101-120 selenium binding protein 1 Homo sapiens 154-157 8403112-9 1993 Subsequently, 16 patients required the infusion of norepinephrine (4-8 micrograms.min-1) to maintain a SBP > 80 mmHg. Norepinephrine 51-65 selenium binding protein 1 Homo sapiens 103-106 7690082-7 1993 Decreases in mean levels of SBP and DBP were observed within 15 min after infusion of > or = 0.5 micrograms/kg CLO. Clonidine 114-117 selenium binding protein 1 Homo sapiens 28-31 8345489-6 1993 It is concluded that BMI, alcohol consumption and the Na/K ratio play an important part in the pattern of male SBP variations in the UK. Alcohols 26-33 selenium binding protein 1 Homo sapiens 111-114 7690384-11 1993 After Gu application in EOH-pts were seen: 1) favourable translocation of the resting (supine) values, but with the same reactivity to tilt, as before Gu (HR, TPR); 2) positive influences on orthostatic reaction, but inversely without any changes of resting values (PEPI, ICT, PEP/LVET, DP, DBP) and finally 3) favourable translocation of resting values together with inversed orthostatic reaction (SBP, QS2,TP). Ethanol 24-27 selenium binding protein 1 Homo sapiens 399-402 8345495-3 1993 After 48 hours caffeine abstention supine SBP was higher over the 120 minute study period following acute caffeine loading than following placebo (10 mmHg; 95% Cl 3-17 mmHg, P = 0.016) although the overall post-caffeine rise from baseline values was small (2 mmHg; -3 to 8 mmHg, P = 0.30). Caffeine 15-23 selenium binding protein 1 Homo sapiens 42-45 8345495-3 1993 After 48 hours caffeine abstention supine SBP was higher over the 120 minute study period following acute caffeine loading than following placebo (10 mmHg; 95% Cl 3-17 mmHg, P = 0.016) although the overall post-caffeine rise from baseline values was small (2 mmHg; -3 to 8 mmHg, P = 0.30). Caffeine 106-114 selenium binding protein 1 Homo sapiens 42-45 8345495-3 1993 After 48 hours caffeine abstention supine SBP was higher over the 120 minute study period following acute caffeine loading than following placebo (10 mmHg; 95% Cl 3-17 mmHg, P = 0.016) although the overall post-caffeine rise from baseline values was small (2 mmHg; -3 to 8 mmHg, P = 0.30). Caffeine 106-114 selenium binding protein 1 Homo sapiens 42-45 8381319-3 1993 This was not affected by 30 min pretreatment of the cells with 0.5 mM of sulphobromophthalein (SBP) an inhibitor of glutathione-S-transferase (GST), by metyrapone or SKF-525A inhibitors of cytochrome P450. Sulfobromophthalein 73-93 selenium binding protein 1 Homo sapiens 95-98 8101194-4 1993 Terazosin and enalapril had a comparable effect on resting BP, reducing systolic (SBP) and diastolic (DBP) blood pressure from 159.5 +/- 13.9/101.6 +/- 8.8 mm Hg during placebo by 7.8%/6.7% and by 11.3%/10.2%, respectively. Terazosin 0-9 selenium binding protein 1 Homo sapiens 82-85 8101194-4 1993 Terazosin and enalapril had a comparable effect on resting BP, reducing systolic (SBP) and diastolic (DBP) blood pressure from 159.5 +/- 13.9/101.6 +/- 8.8 mm Hg during placebo by 7.8%/6.7% and by 11.3%/10.2%, respectively. Enalapril 14-23 selenium binding protein 1 Homo sapiens 82-85 8388711-3 1993 Estradiol, bound to SBP, induced a significant inhibition of SBP-cell binding at a dose of 10(-9) M. The presence of SBP, bound either to estradiol, or to cells, did not alter the amount of estradiol entering cells, but it "captured" an additional quantity of the hormone at the outer surface of cells. Estradiol 0-9 selenium binding protein 1 Homo sapiens 20-23 8388711-3 1993 Estradiol, bound to SBP, induced a significant inhibition of SBP-cell binding at a dose of 10(-9) M. The presence of SBP, bound either to estradiol, or to cells, did not alter the amount of estradiol entering cells, but it "captured" an additional quantity of the hormone at the outer surface of cells. Estradiol 0-9 selenium binding protein 1 Homo sapiens 61-64 8388711-3 1993 Estradiol, bound to SBP, induced a significant inhibition of SBP-cell binding at a dose of 10(-9) M. The presence of SBP, bound either to estradiol, or to cells, did not alter the amount of estradiol entering cells, but it "captured" an additional quantity of the hormone at the outer surface of cells. Estradiol 0-9 selenium binding protein 1 Homo sapiens 61-64 8388711-4 1993 Furthermore, the effect of SBP on estradiol-induced MCF-7 cell proliferation was evaluated. Estradiol 34-43 selenium binding protein 1 Homo sapiens 27-30 8388711-5 1993 While estradiol is an effective proliferating agent on MCF-7 cells, SBP itself did not produce any significant cell proliferation; the growth of MCF-7 cells in the presence of the complex SBP-estradiol was not different from the growth in the presence of estradiol alone; SBP bound to its receptor produced a significant reduction of the estradiol-induced cell proliferation. Estradiol 192-201 selenium binding protein 1 Homo sapiens 188-191 8388711-5 1993 While estradiol is an effective proliferating agent on MCF-7 cells, SBP itself did not produce any significant cell proliferation; the growth of MCF-7 cells in the presence of the complex SBP-estradiol was not different from the growth in the presence of estradiol alone; SBP bound to its receptor produced a significant reduction of the estradiol-induced cell proliferation. Estradiol 192-201 selenium binding protein 1 Homo sapiens 188-191 8388711-5 1993 While estradiol is an effective proliferating agent on MCF-7 cells, SBP itself did not produce any significant cell proliferation; the growth of MCF-7 cells in the presence of the complex SBP-estradiol was not different from the growth in the presence of estradiol alone; SBP bound to its receptor produced a significant reduction of the estradiol-induced cell proliferation. Estradiol 192-201 selenium binding protein 1 Homo sapiens 188-191 8388711-5 1993 While estradiol is an effective proliferating agent on MCF-7 cells, SBP itself did not produce any significant cell proliferation; the growth of MCF-7 cells in the presence of the complex SBP-estradiol was not different from the growth in the presence of estradiol alone; SBP bound to its receptor produced a significant reduction of the estradiol-induced cell proliferation. Estradiol 192-201 selenium binding protein 1 Homo sapiens 188-191 8388711-6 1993 In summary, the present study provides evidence that the interaction of SBP with its receptor on MCF-7 cells is not involved in the uptake of estradiol, but it can modify the effect of estradiol at target site by a mechanism which is not likely to be a simple sequestration of the hormone at the outer surface of cells. Estradiol 185-194 selenium binding protein 1 Homo sapiens 72-75 8492963-8 1993 Chol./HDL-C, LDL-C/HDL-C. During follow-up the blood pressure values were significantly reduced (p < 0.01) (captopril: delta SBP = -13.88, delta DBP = -12.38, nifedipine: delta SBP = -22.03, delta DBP = -21.35). Captopril 111-120 selenium binding protein 1 Homo sapiens 128-131 8424391-3 1993 Plasma concentrations of ascorbic acid (AA) were significantly inversely related to SBP (r = -0.18, P < 0.05) and DBP (r = -0.20, P < 0.01); with regression equations SBP vs AA = -0.083C + 116 and DBP = -0.077C + 76. Ascorbic Acid 25-38 selenium binding protein 1 Homo sapiens 84-87 8424391-3 1993 Plasma concentrations of ascorbic acid (AA) were significantly inversely related to SBP (r = -0.18, P < 0.05) and DBP (r = -0.20, P < 0.01); with regression equations SBP vs AA = -0.083C + 116 and DBP = -0.077C + 76. Ascorbic Acid 25-38 selenium binding protein 1 Homo sapiens 173-176 8381319-3 1993 This was not affected by 30 min pretreatment of the cells with 0.5 mM of sulphobromophthalein (SBP) an inhibitor of glutathione-S-transferase (GST), by metyrapone or SKF-525A inhibitors of cytochrome P450. Metyrapone 152-162 selenium binding protein 1 Homo sapiens 95-98 8458057-6 1993 Between baseline and the end of maintenance, ramipril decreased mean supine systolic/diastolic blood pressure (SBP/DBP) measured 24 hours after the last dose by 9/8 mmHg (P < or = 0.001/P < or = 0.001); placebo decreased SBP/DBP by 2/4 mmHg (NS/P < or = 0.05). Ramipril 45-53 selenium binding protein 1 Homo sapiens 111-114 8458057-6 1993 Between baseline and the end of maintenance, ramipril decreased mean supine systolic/diastolic blood pressure (SBP/DBP) measured 24 hours after the last dose by 9/8 mmHg (P < or = 0.001/P < or = 0.001); placebo decreased SBP/DBP by 2/4 mmHg (NS/P < or = 0.05). Ramipril 45-53 selenium binding protein 1 Homo sapiens 227-230 8436150-4 1993 As compared to randomised placebo, isradipine SRO significantly reduced the systolic (SBP) and diastolic (DBP) blood pressure. isradipine sro 35-49 selenium binding protein 1 Homo sapiens 86-89 8299661-8 1993 At the end of amlodipine administration a significant decrease (P < 0.001) in SBP, DBP and MBP from baseline values was observed. Amlodipine 14-24 selenium binding protein 1 Homo sapiens 81-84 1444777-6 1992 FES-LCE training significantly increased resting HR and SBP in quadriplegics and lowered SBP, DBP, and MAP in paraplegics. fes-lce 0-7 selenium binding protein 1 Homo sapiens 56-59 8491238-6 1993 In relation to the plasma drug concentration, metoprolol had four-times and twice the effect on heart rate and SBP during pregnancy as compared to the post partum period. Metoprolol 46-56 selenium binding protein 1 Homo sapiens 111-114 1293305-7 1992 However, amlodipine reduced ambulatory systolic (SBP) and DBP almost every hour over the whole circadian cycle, whereas the antihypertensive effect of captopril was attenuated during the final 3 hours of each dosing interval. Amlodipine 9-19 selenium binding protein 1 Homo sapiens 49-52 8385525-3 1993 Lisinopril lowered mean 24 hour systolic blood pressure significantly more than enalapril after 4 weeks of treatment (14/7 +/- 2/1mmHg & 9/6 +/- 2/1mmHg, respectively, adjusted SBP difference 4.8mmHg, P < 0.01). Lisinopril 0-10 selenium binding protein 1 Homo sapiens 181-184 1444777-6 1992 FES-LCE training significantly increased resting HR and SBP in quadriplegics and lowered SBP, DBP, and MAP in paraplegics. fes-lce 0-7 selenium binding protein 1 Homo sapiens 89-92 1397258-0 1992 Localization of the steroid-binding site of the human sex steroid-binding protein of plasma (SBP or SHBG) by site-directed mutagenesis. Steroids 20-27 selenium binding protein 1 Homo sapiens 93-96 1397258-0 1992 Localization of the steroid-binding site of the human sex steroid-binding protein of plasma (SBP or SHBG) by site-directed mutagenesis. Steroids 58-65 selenium binding protein 1 Homo sapiens 93-96 1397258-1 1992 The amino-terminal region of the human sex steroid-binding protein of plasma (SBP or SHBG) containing K134 and M139 was found to represent part of the steroid-binding site. Steroids 43-50 selenium binding protein 1 Homo sapiens 78-81 1397258-1 1992 The amino-terminal region of the human sex steroid-binding protein of plasma (SBP or SHBG) containing K134 and M139 was found to represent part of the steroid-binding site. Steroids 151-158 selenium binding protein 1 Homo sapiens 78-81 1314639-5 1992 The effect of steroid hormones on SBP-receptor interaction was also evaluated. Steroids 14-30 selenium binding protein 1 Homo sapiens 34-37 1280705-3 1992 Alacepril (50 mg/day) caused a significant decrease in both systolic and diastolic blood pressure (SBP and DBP, from 161 +/- 8 to 140 +/- 10 mm Hg and from 100 +/- 3 to 90 +/- 5 mm Hg, respectively). alacepril 0-9 selenium binding protein 1 Homo sapiens 99-102 1337711-5 1992 One hour after oral glucose load the increase of glycemia and insulinemia was significantly higher in the group of subjects with SBP > 140 and/or DBP > 90 mmHg than in normotensive subjects (p < 0.001). Glucose 20-27 selenium binding protein 1 Homo sapiens 129-132 1304375-0 1992 Complete enzymatic deglycosylation of native sex steroid-binding protein (SBP or SHBG) of human and rabbit plasma: effect on the steroid-binding activity. Steroids 49-56 selenium binding protein 1 Homo sapiens 74-77 1304375-1 1992 An enzymatic procedure for the complete removal of the N-linked and O-linked oligosaccharide side chains of the sex steroid-binding proteins (SBP or SHBG) of human and rabbit plasma under native conditions is described. n-linked and o-linked oligosaccharide 55-92 selenium binding protein 1 Homo sapiens 142-145 1304375-1 1992 An enzymatic procedure for the complete removal of the N-linked and O-linked oligosaccharide side chains of the sex steroid-binding proteins (SBP or SHBG) of human and rabbit plasma under native conditions is described. Steroids 116-123 selenium binding protein 1 Homo sapiens 142-145 1304375-9 1992 N-deglycosylation of human and rabbit SBP has no effect on the steroid-binding activity, but removal of the O-linked side chains of N-deglycosylated human SBP results in an apparent 50% loss of steroid-binding activity and an increase in the Kd for the binding of 5 alpha-dihydrotestosterone from 0.3 mM to 0.9 nM. Steroids 194-201 selenium binding protein 1 Homo sapiens 155-158 1304375-9 1992 N-deglycosylation of human and rabbit SBP has no effect on the steroid-binding activity, but removal of the O-linked side chains of N-deglycosylated human SBP results in an apparent 50% loss of steroid-binding activity and an increase in the Kd for the binding of 5 alpha-dihydrotestosterone from 0.3 mM to 0.9 nM. alpha-dihydrotestosterone 266-291 selenium binding protein 1 Homo sapiens 155-158 1623657-3 1992 At end study diltiazem CD changed trough supine SBP and DBP by -8.4 +/- 1.7 (p = 0.0009) and -8.6 +/- 1.1 mmHg (p = 0.0075), respectively. diltiazem cd 13-25 selenium binding protein 1 Homo sapiens 48-51 1623657-7 1992 Diltiazem CD lowered DBP and SBP throughout the dosing interval. Diltiazem 0-9 selenium binding protein 1 Homo sapiens 29-32 1318734-9 1992 Its incubation with labelled rABP and hSBP provoked the elution of the tracer as an aggregate into the void volume fraction of superose 6B mini-gel filtration columns. Superose 6b 127-138 selenium binding protein 1 Homo sapiens 38-42 1318734-10 1992 Structural homology between hSBP and rABP could be responsible for the common behaviour of the steroid-carrier molecules for the ABP receptor of rat epididymal epithelial cells. Steroids 95-102 selenium binding protein 1 Homo sapiens 28-32 1430842-1 1992 The abnormal concentrations of steroid hormones and free fatty acids in the plasma of HIV-infected subjects are associated with qualitative and quantitative alterations in two of the major steroid hormones carrier proteins, sex steroid-binding protein (SBP) and corticosteroid-binding globulin (CBG). Steroids 31-47 selenium binding protein 1 Homo sapiens 253-256 1430842-1 1992 The abnormal concentrations of steroid hormones and free fatty acids in the plasma of HIV-infected subjects are associated with qualitative and quantitative alterations in two of the major steroid hormones carrier proteins, sex steroid-binding protein (SBP) and corticosteroid-binding globulin (CBG). Fatty Acids, Nonesterified 52-68 selenium binding protein 1 Homo sapiens 253-256 1430842-4 1992 The sera of AIDS patients had higher SBP association constants (Ka) for testosterone than did those of the II, III and IVA groups and controls. Testosterone 72-84 selenium binding protein 1 Homo sapiens 37-40 1333656-5 1992 The effect exerted by sex steroids on the interaction of SBP with receptor was also examined on both the soluble and membrane-bound forms. Steroids 26-34 selenium binding protein 1 Homo sapiens 57-60 1333656-7 1992 The dose of estradiol required to significantly inhibit the SBP-specific binding was dependent on the form of receptor. Estradiol 12-21 selenium binding protein 1 Homo sapiens 60-63 1444161-2 1992 After 6 months a significant reduction of SBP and DBP (p < 0.001), with improvement of creatinine clearance and with no adverse effects on ECG, heart rate and routine laboratory tests test, was observed in 3 patients treated with N 20 mg x 2/d + E 10 mg/d + A 50 mg/d and in 8 patients treated with N 20 mg x 3 + E 10 mg x 2, + A 50 mg x 2. Nitrogen 233-234 selenium binding protein 1 Homo sapiens 42-45 1619199-7 1992 In boys triglycerides, ApoB and the ratio ApoAI/ApoB were related to WHR for insulin, SBP and DBP, but a positive association with the WHR was found, explaining 33, 21.8, and 22.6% of the variance. Triglycerides 8-21 selenium binding protein 1 Homo sapiens 86-89 1599384-9 1992 For the women only, SBP, DBP, and HR were correlated with T Chol, and Trig and HDL-C were correlated with T Ca. chol 60-64 selenium binding protein 1 Homo sapiens 20-23 1314639-6 1992 Both dihydrotestosterone and estradiol were shown to inhibit the binding of SBP to its specific receptor on neoplastic membranes. Dihydrotestosterone 5-24 selenium binding protein 1 Homo sapiens 76-79 1314639-6 1992 Both dihydrotestosterone and estradiol were shown to inhibit the binding of SBP to its specific receptor on neoplastic membranes. Estradiol 29-38 selenium binding protein 1 Homo sapiens 76-79 1298945-8 1992 Comparison data for 25 women from the CHBPP population showed a mean SBP/DBP increase of 8/2 mmHg over an 8-week interval. chbpp 38-43 selenium binding protein 1 Homo sapiens 69-72 1544469-0 1992 Mammalian expression of the human sex steroid-binding protein of plasma (SBP or SHBG) and testis (ABP). Steroids 38-45 selenium binding protein 1 Homo sapiens 73-76 1540179-0 1992 A metabolite of acetaminophen covalently binds to the 56 kDa selenium binding protein. Acetaminophen 16-29 selenium binding protein 1 Homo sapiens 54-85 1665184-3 1991 SBP reduction from baseline in the L/HCTZ group was significantly greater, sitting and standing, compared with both the monotherapy groups. Hydrochlorothiazide 37-41 selenium binding protein 1 Homo sapiens 0-3 1283570-4 1992 With verapamil SR 480 mg/day, 91% of patients had reductions in SBP and DBP greater than 20 and 15mm Hg, respectively. Verapamil 5-17 selenium binding protein 1 Homo sapiens 64-67 1376842-6 1992 Comparison of systolic (SBP) and diastolic (DBP) blood pressures with isradipine indicated that there were significantly greater average decreases in SBP at 0600-0800 h than at 1800-2000 h (p = 0.038), and at 0800-1100 h than at 2000-2300 h (p = 0.045). Isradipine 70-80 selenium binding protein 1 Homo sapiens 150-153 1377306-5 1992 Chronic administration of nitrendipine resulted in a more effective lowering of the SBP and DBP mesor, compared with placebo and acute administration, preserving the circadian rhythms. Nitrendipine 26-38 selenium binding protein 1 Homo sapiens 84-87 1751398-0 1991 In vivo and in vitro studies on sex steroid binding protein (SBP) regulation in rainbow trout (Oncorhynchus mykiss): influence of sex steroid hormones and of factors linked to growth and metabolism. Steroids 36-43 selenium binding protein 1 Homo sapiens 61-64 1751398-2 1991 In vivo, oestradiol (E2) supplementation induces a slow but significant increase of plasma SBP concentration. Estradiol 9-19 selenium binding protein 1 Homo sapiens 91-94 1751398-2 1991 In vivo, oestradiol (E2) supplementation induces a slow but significant increase of plasma SBP concentration. Estradiol 21-23 selenium binding protein 1 Homo sapiens 91-94 1911434-0 1991 Hormone-associated variation of the glycan microheterogeneity pattern of human sex steroid-binding protein (hSBP). Polysaccharides 36-42 selenium binding protein 1 Homo sapiens 108-112 1763923-6 1991 After two months treatment, the systolic and diastolic blood pressures were significantly lower at rest in the nicardipine than in the placebo group (delta SBP = -18.9 vs -4.1 mmHg, p less than 0.001; delta DBP = -15.7 vs -4.1 mmHg, p less than 0.01). Nicardipine 111-122 selenium binding protein 1 Homo sapiens 156-159 1763923-7 1991 In addition the maximum SBP on effort was significantly lower in the nicardipine group (200 vs 215 mmHg, p less than 0.05). Nicardipine 69-80 selenium binding protein 1 Homo sapiens 24-27 1839656-4 1991 After treatment with isradipine sBP fell from 168.0 to 148.1 and dBP from 102.7 to 86.7 mmHg. Isradipine 21-31 selenium binding protein 1 Homo sapiens 32-35 1682112-3 1991 Esmolol infusion (8 to 24 mg/min) produced large decreases in heart rate (84 +/- 2 to 69 +/- 2 beats/min, p less than 0.01) and SBP (124 +/- 3 to 106 +/- 3 mm Hg, p less than 0.01). esmolol 0-7 selenium binding protein 1 Homo sapiens 128-131 1683818-7 1991 Esmolol was less effective in controlling blood pressure, but, in combination with low-dose narcotic, esmolol suppressed the SBP response to tracheal intubation. esmolol 102-109 selenium binding protein 1 Homo sapiens 125-128 1683818-8 1991 In the presence of moderate-dose narcotic, however, a decrease in SBP occurred in all three groups following induction of anaesthesia (P less than 0.003), with the largest decrease (17 +/- 4%) occurring in patients who had received E200. diphenazine 232-236 selenium binding protein 1 Homo sapiens 66-69 1911434-6 1991 An explanation for these differences is given and the role of the glycan moiety of hSBP is discussed. Polysaccharides 66-72 selenium binding protein 1 Homo sapiens 83-87 1832761-5 1991 Both groups were similar at randomisation, and both treatments were similarly effective: after 8 weeks of monotherapy with rilmenidine or atenolol, the SBP/DBP had decreased by -18/-13 mmHg and by -21/-15 mmHg respectively, and the proportion of patients with normalised blood pressure (SBP/DBP less than or equal to 160/90 mmHg) was 66 percent and 65 percent. Rilmenidine 123-134 selenium binding protein 1 Homo sapiens 152-155 1832761-5 1991 Both groups were similar at randomisation, and both treatments were similarly effective: after 8 weeks of monotherapy with rilmenidine or atenolol, the SBP/DBP had decreased by -18/-13 mmHg and by -21/-15 mmHg respectively, and the proportion of patients with normalised blood pressure (SBP/DBP less than or equal to 160/90 mmHg) was 66 percent and 65 percent. Rilmenidine 123-134 selenium binding protein 1 Homo sapiens 287-290 1832761-5 1991 Both groups were similar at randomisation, and both treatments were similarly effective: after 8 weeks of monotherapy with rilmenidine or atenolol, the SBP/DBP had decreased by -18/-13 mmHg and by -21/-15 mmHg respectively, and the proportion of patients with normalised blood pressure (SBP/DBP less than or equal to 160/90 mmHg) was 66 percent and 65 percent. Atenolol 138-146 selenium binding protein 1 Homo sapiens 152-155 1832761-5 1991 Both groups were similar at randomisation, and both treatments were similarly effective: after 8 weeks of monotherapy with rilmenidine or atenolol, the SBP/DBP had decreased by -18/-13 mmHg and by -21/-15 mmHg respectively, and the proportion of patients with normalised blood pressure (SBP/DBP less than or equal to 160/90 mmHg) was 66 percent and 65 percent. Atenolol 138-146 selenium binding protein 1 Homo sapiens 287-290 1954595-8 1991 The delta SBP (exercise SBP minus resting SBP) at the first stage of the CAFT could also be utilized to identify persons who demonstrate an abnormal pressure response to exercise. caft 73-77 selenium binding protein 1 Homo sapiens 10-13 1956126-8 1991 SBP with a same oxygen-uptake load during submaximal work increased in group H, but decreased in group L. 6) Rate pressure products both at rest and during submaximal exercise decreased significantly in group L. 7) Serum lipid levels remained in all groups. Oxygen 16-22 selenium binding protein 1 Homo sapiens 0-3 1779513-3 1991 A single dose of anapriline resulted in a significant reduction in SBP and MBP at rest and during dynamic exercise (p less than 0.05-0.001), in DBP at rest (p less than 0.05) and in an insignificant decrease in SBP, DBP, and MBP during isometric exercise and DBP during dynamic exercise. Propranolol 17-27 selenium binding protein 1 Homo sapiens 67-70 1779513-3 1991 A single dose of anapriline resulted in a significant reduction in SBP and MBP at rest and during dynamic exercise (p less than 0.05-0.001), in DBP at rest (p less than 0.05) and in an insignificant decrease in SBP, DBP, and MBP during isometric exercise and DBP during dynamic exercise. Propranolol 17-27 selenium binding protein 1 Homo sapiens 211-214 1954595-8 1991 The delta SBP (exercise SBP minus resting SBP) at the first stage of the CAFT could also be utilized to identify persons who demonstrate an abnormal pressure response to exercise. caft 73-77 selenium binding protein 1 Homo sapiens 24-27 1954595-8 1991 The delta SBP (exercise SBP minus resting SBP) at the first stage of the CAFT could also be utilized to identify persons who demonstrate an abnormal pressure response to exercise. caft 73-77 selenium binding protein 1 Homo sapiens 24-27 2065721-4 1991 In all patients, ketanserin significantly lowered IOP and SBP, while no variations in pupil diameter, DBP and HR were found. Ketanserin 17-27 selenium binding protein 1 Homo sapiens 58-61 1907862-1 1991 In heifers, the specific 5 alpha-dihydrotestosterone (5 alpha-DHT) binding to sex steroid-binding protein (SBP) was 53 nM in midluteal phase and was 20% lower (p less than 0.05) in early luteal phase. Dihydrotestosterone 25-52 selenium binding protein 1 Homo sapiens 107-110 1907862-1 1991 In heifers, the specific 5 alpha-dihydrotestosterone (5 alpha-DHT) binding to sex steroid-binding protein (SBP) was 53 nM in midluteal phase and was 20% lower (p less than 0.05) in early luteal phase. Dihydrotestosterone 54-65 selenium binding protein 1 Homo sapiens 107-110 1907862-2 1991 In ovariectomized heifers on a high (H) or a low (L) energy diet, SBP bound testosterone with high specificity and estradiol-17 beta (E2) with a lower specificity; the affinity constant with 5 alpha-DHT was similar in the two groups independent of diet (Ka = 1.0 and 1.3 x 10(9) x M-1 for H and L heifers, respectively). Testosterone 76-88 selenium binding protein 1 Homo sapiens 66-69 1907862-6 1991 Porcine growth hormone (pGH) and E2 injections increased specific 5 alpha-DHT binding to SBP in both H and L heifers, but the effect depended on diet. GH2 protein, human 24-27 selenium binding protein 1 Homo sapiens 89-92 1907862-6 1991 Porcine growth hormone (pGH) and E2 injections increased specific 5 alpha-DHT binding to SBP in both H and L heifers, but the effect depended on diet. Dihydrotestosterone 73-77 selenium binding protein 1 Homo sapiens 89-92 1907862-8 1991 We conclude that SBP binding capacity varies with ovarian activity in heifers and that nutritional status is one factor of regulation of SBP binding capacity because it affects binding and modifies the SBP response to stimulating factors such as pGH and E2. GH2 protein, human 246-249 selenium binding protein 1 Homo sapiens 137-140 1907862-8 1991 We conclude that SBP binding capacity varies with ovarian activity in heifers and that nutritional status is one factor of regulation of SBP binding capacity because it affects binding and modifies the SBP response to stimulating factors such as pGH and E2. GH2 protein, human 246-249 selenium binding protein 1 Homo sapiens 137-140 1907862-8 1991 We conclude that SBP binding capacity varies with ovarian activity in heifers and that nutritional status is one factor of regulation of SBP binding capacity because it affects binding and modifies the SBP response to stimulating factors such as pGH and E2. Estradiol 254-256 selenium binding protein 1 Homo sapiens 137-140 1907862-8 1991 We conclude that SBP binding capacity varies with ovarian activity in heifers and that nutritional status is one factor of regulation of SBP binding capacity because it affects binding and modifies the SBP response to stimulating factors such as pGH and E2. Estradiol 254-256 selenium binding protein 1 Homo sapiens 137-140 1649859-5 1991 Other factors that independently predicted an increase in SBP were baseline fasting insulin, parental history of hypertension and increases in body mass index and in alcohol intake across the 3 years of follow-up. Alcohols 166-173 selenium binding protein 1 Homo sapiens 58-61 1878323-6 1991 Average reactivities during CONFLICT + SODIUM periods were 11.2/7.9% delta for SBP/DBP (systolic/diastolic blood pressure, mmHg), and -5.65% delta for HR (heart rate, BPM). Sodium 39-45 selenium binding protein 1 Homo sapiens 79-82 1713985-5 1991 Systolic blood pressure/heart rate (SBP/HR) product at maximum workload remained almost constant with 253 +/- 43 with placebo and 253 +/- 39 with benazepril treatment. benazepril 146-156 selenium binding protein 1 Homo sapiens 36-42 1920817-5 1991 The combination of KET + HCTZ in the acute study reduced significantly systolic (SBP) and diastolic (DBP) blood pressures for up to 10 hrs. Ketanserin 19-22 selenium binding protein 1 Homo sapiens 81-84 1920817-5 1991 The combination of KET + HCTZ in the acute study reduced significantly systolic (SBP) and diastolic (DBP) blood pressures for up to 10 hrs. Hydrochlorothiazide 25-29 selenium binding protein 1 Homo sapiens 81-84 2060561-11 1991 There were larger increases in SBP with isoprenaline in both groups. Isoproterenol 40-52 selenium binding protein 1 Homo sapiens 31-34 1785775-1 1991 We investigate in this study the hypothesis of human sex steroid-binding protein hSBP internalization into germ cells in a primate model. Steroids 57-64 selenium binding protein 1 Homo sapiens 81-85 1785775-2 1991 Human SBP was purified from late-pregnancy serum and labeled either with colloidal gold particles (18 nm) or with [3H]delta 6-testosterone by photoaffinity treatment. Tritium 115-117 selenium binding protein 1 Homo sapiens 6-9 1785775-2 1991 Human SBP was purified from late-pregnancy serum and labeled either with colloidal gold particles (18 nm) or with [3H]delta 6-testosterone by photoaffinity treatment. 6-dehydrotestosterone 118-138 selenium binding protein 1 Homo sapiens 6-9 1785775-13 1991 EDTA pretreatment strongly decreased hSBP internalization and modified the early endocytic steps, namely, the pinching off of the coated vesicles. Edetic Acid 0-4 selenium binding protein 1 Homo sapiens 37-41 1723456-4 1991 Nitrendipine significantly reduced the SBP and DBP mesors without affecting the HR mesor, and reduced the SBP and DBP amplitudes while increasing the HR amplitude. Nitrendipine 0-12 selenium binding protein 1 Homo sapiens 39-42 1884720-8 1991 In the diltiazem group, supine BP was reduced by 10 (11)/10 (6) mmHg (SBP/DBP) at the highest dose level, and the corresponding values for the metoprolol group were 7 (16)/8 (9) mmHg (SBP/DBP). Diltiazem 7-16 selenium binding protein 1 Homo sapiens 70-73 1884720-8 1991 In the diltiazem group, supine BP was reduced by 10 (11)/10 (6) mmHg (SBP/DBP) at the highest dose level, and the corresponding values for the metoprolol group were 7 (16)/8 (9) mmHg (SBP/DBP). Diltiazem 7-16 selenium binding protein 1 Homo sapiens 184-187 1687786-4 1991 Nifedipine produced no significant changes in HR and cardiac output (CO) at rest, but augmented the increase in HR (delta HR) and SBP (delta SBP) during submaximal exercise. Nifedipine 0-10 selenium binding protein 1 Homo sapiens 112-144 1723456-4 1991 Nitrendipine significantly reduced the SBP and DBP mesors without affecting the HR mesor, and reduced the SBP and DBP amplitudes while increasing the HR amplitude. Nitrendipine 0-12 selenium binding protein 1 Homo sapiens 106-109 1659891-2 1991 The hormonal regulation studies of hepatic SBP mRNA demonstrate that it is controlled by estradiol, antiestrogen tamoxifen, dihydrotestosterone, triiodothyronine and insulin in a similar way as secreted SBP. Estradiol 89-98 selenium binding protein 1 Homo sapiens 43-46 1659891-2 1991 The hormonal regulation studies of hepatic SBP mRNA demonstrate that it is controlled by estradiol, antiestrogen tamoxifen, dihydrotestosterone, triiodothyronine and insulin in a similar way as secreted SBP. Tamoxifen 113-122 selenium binding protein 1 Homo sapiens 43-46 1659891-2 1991 The hormonal regulation studies of hepatic SBP mRNA demonstrate that it is controlled by estradiol, antiestrogen tamoxifen, dihydrotestosterone, triiodothyronine and insulin in a similar way as secreted SBP. Dihydrotestosterone 124-143 selenium binding protein 1 Homo sapiens 43-46 1659891-2 1991 The hormonal regulation studies of hepatic SBP mRNA demonstrate that it is controlled by estradiol, antiestrogen tamoxifen, dihydrotestosterone, triiodothyronine and insulin in a similar way as secreted SBP. Triiodothyronine 145-161 selenium binding protein 1 Homo sapiens 43-46 1659891-4 1991 The slight stimulation of SBP synthesis by estradiol suggests that non-steroidal factors may be involved in its regulation and that the estrogen regulatory mechanism could also be partly post-transcriptional. Estradiol 43-52 selenium binding protein 1 Homo sapiens 26-29 1659891-5 1991 In endometrial (Ishikawa cells) and prostatic (LNCaP cells) carcinoma cells, SBP mRNA has been detected suggesting that SBP may play a role in the uptake and intracellular mechanism of action of sex steroid in target cells. Steroids 199-206 selenium binding protein 1 Homo sapiens 77-80 1659891-5 1991 In endometrial (Ishikawa cells) and prostatic (LNCaP cells) carcinoma cells, SBP mRNA has been detected suggesting that SBP may play a role in the uptake and intracellular mechanism of action of sex steroid in target cells. Steroids 199-206 selenium binding protein 1 Homo sapiens 120-123 1659893-1 1991 Since the discovery of a specific membrane binding site for sex steroid binding protein (SBP) in human decidual endometrium and in hyperplastic prostate numerous speculations have been raised on the existence of an additional non-receptor-mediated system for steroid hormone action. Steroids 259-274 selenium binding protein 1 Homo sapiens 89-92 1659893-5 1991 The different patterns of specific binding, observed in membranes from different tissues when SBP was liganded with different sex steroid molecules, leads us to consider the tissue individuality of the receptor as a further entity in the membrane recognition system for SBP. Steroids 130-137 selenium binding protein 1 Homo sapiens 94-97 2303822-1 1990 Serotonin binding protein (SBP) is a vesicular protein found in neurectoderm-derived cells that store 5-hydroxytryptamine (5-HT, serotonin), such as central and peripheral serotonergic neurons and paraneurons (parafollicular cells of the thyroid). Serotonin 102-121 selenium binding protein 1 Homo sapiens 0-25 2096199-3 1990 The sodium/creatinine ratio [r = 0.10 (P less than 0.001)] and sodium/potassium ratio [r = 0.11 (P less than 0.001)] were positively correlated with SBP. Sodium 4-10 selenium binding protein 1 Homo sapiens 149-152 2096199-3 1990 The sodium/creatinine ratio [r = 0.10 (P less than 0.001)] and sodium/potassium ratio [r = 0.11 (P less than 0.001)] were positively correlated with SBP. Creatinine 11-21 selenium binding protein 1 Homo sapiens 149-152 2096199-3 1990 The sodium/creatinine ratio [r = 0.10 (P less than 0.001)] and sodium/potassium ratio [r = 0.11 (P less than 0.001)] were positively correlated with SBP. Sodium 63-69 selenium binding protein 1 Homo sapiens 149-152 2096199-3 1990 The sodium/creatinine ratio [r = 0.10 (P less than 0.001)] and sodium/potassium ratio [r = 0.11 (P less than 0.001)] were positively correlated with SBP. Potassium 70-79 selenium binding protein 1 Homo sapiens 149-152 2283637-8 1990 A linear correlation existed between Nai and both systolic (SBP) and diastolic (DBP) (r = 0.378 and 0.339, respectively; P less than 0.01), which was strongest among the blacks, particularly the US blacks (SBP vs. Nai, r = 0.716, P less than 0.01). Sodium Iodide 37-40 selenium binding protein 1 Homo sapiens 60-63 2283637-8 1990 A linear correlation existed between Nai and both systolic (SBP) and diastolic (DBP) (r = 0.378 and 0.339, respectively; P less than 0.01), which was strongest among the blacks, particularly the US blacks (SBP vs. Nai, r = 0.716, P less than 0.01). Sodium Iodide 37-40 selenium binding protein 1 Homo sapiens 206-209 2283637-8 1990 A linear correlation existed between Nai and both systolic (SBP) and diastolic (DBP) (r = 0.378 and 0.339, respectively; P less than 0.01), which was strongest among the blacks, particularly the US blacks (SBP vs. Nai, r = 0.716, P less than 0.01). Sodium Iodide 214-217 selenium binding protein 1 Homo sapiens 60-63 2080194-3 1990 Testosterone levels in women were positively correlated with SBP, DBP and HR, after removing the effects of age and body mass. Testosterone 0-12 selenium binding protein 1 Homo sapiens 61-64 2365539-7 1990 Ketanserin significantly reduced both SBP and DBP (p less than 0.005) with no changes in HR. Ketanserin 0-10 selenium binding protein 1 Homo sapiens 38-41 2245422-8 1990 After prazosin treatment SBP increase induced by IHT was, on the contrary, significantly more elevated in BH than in SH or in C. This increase is more significant in comparison with that observed in the same BH group after placebo treatment. Prazosin 6-14 selenium binding protein 1 Homo sapiens 25-28 2245422-8 1990 After prazosin treatment SBP increase induced by IHT was, on the contrary, significantly more elevated in BH than in SH or in C. This increase is more significant in comparison with that observed in the same BH group after placebo treatment. Bh 106-108 selenium binding protein 1 Homo sapiens 25-28 2126929-1 1990 Human sex steroid-binding protein (hSBP) has been purified from late-pregnancy serum and labelled either by iodination (125I) or by photoaffinity with [3H]delta 6-testosterone. Tritium 152-154 selenium binding protein 1 Homo sapiens 35-39 2126929-1 1990 Human sex steroid-binding protein (hSBP) has been purified from late-pregnancy serum and labelled either by iodination (125I) or by photoaffinity with [3H]delta 6-testosterone. 6-dehydrotestosterone 155-175 selenium binding protein 1 Homo sapiens 35-39 2126929-13 1990 To what extent the chemical and structural homology between hSBP and rABP can be held responsible for the common cytophysiological behaviour of these sex steroid-binding proteins remains to be determined. Steroids 154-161 selenium binding protein 1 Homo sapiens 60-64 2288636-3 1990 After castration, the SBP concentration increased in the serum but was reduced after testosterone treatment. Testosterone 85-97 selenium binding protein 1 Homo sapiens 22-25 2288636-4 1990 In contrast, the hepatic SBP mRNA level decreased after castration and was restored by testosterone treatment. Testosterone 87-99 selenium binding protein 1 Homo sapiens 25-28 2120231-1 1990 The sex steroid-binding protein of human plasma SBP (or sex hormone-binding globulin, SHBG) was specifically inhibited with the alkylating affinity label, 17 beta-[[( 2-14C]bromoacetyl)oxy]-5 alpha-androstan-3-one. Steroids 8-15 selenium binding protein 1 Homo sapiens 48-51 2120231-1 1990 The sex steroid-binding protein of human plasma SBP (or sex hormone-binding globulin, SHBG) was specifically inhibited with the alkylating affinity label, 17 beta-[[( 2-14C]bromoacetyl)oxy]-5 alpha-androstan-3-one. beta-[[( 2-14c]bromoacetyl)oxy]-5 alpha-androstan-3-one 158-213 selenium binding protein 1 Homo sapiens 48-51 2120231-3 1990 The steroid-binding activity of the protein was abolished when approximately 1 mol of label was incorporated into 1 mol of dimeric SBP. Steroids 4-11 selenium binding protein 1 Homo sapiens 131-134 2120231-6 1990 Residue X was identified as lysine-134 from the SBP amino acid sequence (Walsh, K. A., Titani, K., Kumar, S., Hayes, R., and Petra, P. H. (1986) Biochemistry 25, 7584-7590). Lysine 28-34 selenium binding protein 1 Homo sapiens 48-51 2303822-1 1990 Serotonin binding protein (SBP) is a vesicular protein found in neurectoderm-derived cells that store 5-hydroxytryptamine (5-HT, serotonin), such as central and peripheral serotonergic neurons and paraneurons (parafollicular cells of the thyroid). Serotonin 102-121 selenium binding protein 1 Homo sapiens 27-30 2303822-1 1990 Serotonin binding protein (SBP) is a vesicular protein found in neurectoderm-derived cells that store 5-hydroxytryptamine (5-HT, serotonin), such as central and peripheral serotonergic neurons and paraneurons (parafollicular cells of the thyroid). Serotonin 129-138 selenium binding protein 1 Homo sapiens 0-25 2303822-1 1990 Serotonin binding protein (SBP) is a vesicular protein found in neurectoderm-derived cells that store 5-hydroxytryptamine (5-HT, serotonin), such as central and peripheral serotonergic neurons and paraneurons (parafollicular cells of the thyroid). Serotonin 129-138 selenium binding protein 1 Homo sapiens 27-30 2303822-8 1990 A 1 M excess of NAP-5-HT inhibited the binding of [3H]5-HT to SBP by 50%. Bufotenin 22-24 selenium binding protein 1 Homo sapiens 62-65 2303822-8 1990 A 1 M excess of NAP-5-HT inhibited the binding of [3H]5-HT to SBP by 50%. Tritium 51-53 selenium binding protein 1 Homo sapiens 62-65 2303822-9 1990 NAP[3H]5-HT was also synthesized and attached to both high- and low-affinity binding sites on both forms of SBP. Tritium 4-6 selenium binding protein 1 Homo sapiens 108-111 2245422-11 1990 SBP hyperreactivity induced by IHT after alpha sympatholytic treatment and DBP hyporeactivity after betablockers emphasize the role of beta stimulation in BH individuals. Bh 155-157 selenium binding protein 1 Homo sapiens 0-3 2303822-11 1990 When the high-affinity site of partially purified SBP was photoaffinity-labeled with the reagent, two covalently labeled proteins (45 kDa and 56 kDa) were found by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). Sodium Dodecyl Sulfate 164-186 selenium binding protein 1 Homo sapiens 50-53 2303822-11 1990 When the high-affinity site of partially purified SBP was photoaffinity-labeled with the reagent, two covalently labeled proteins (45 kDa and 56 kDa) were found by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). polyacrylamide 187-201 selenium binding protein 1 Homo sapiens 50-53 2303822-11 1990 When the high-affinity site of partially purified SBP was photoaffinity-labeled with the reagent, two covalently labeled proteins (45 kDa and 56 kDa) were found by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). Sodium Dodecyl Sulfate 223-226 selenium binding protein 1 Homo sapiens 50-53 3221006-6 1988 The effect of nifedipine was more pronounced on the DBP than on the SBP, and greater reductions of both pressures were achieved in the cases with higher initial readings. Nifedipine 14-24 selenium binding protein 1 Homo sapiens 68-71 1706014-3 1990 In the groups treated with diltiazem, enalapril, or the combination of both, the drop in arterial blood pressure was 20, 11, and 19 mm Hg for supine diastolic blood pressure (supine DBP): 18, 12, and 19 mm Hg for standing diastolic blood pressure (standing DBP); 22, 20, and 23 mm Hg for supine systolic blood pressure (supine SBP); and 21, 19, and 24 mm Hg for standing systolic blood pressure (standing SBP), respectively. Diltiazem 27-36 selenium binding protein 1 Homo sapiens 327-330 1706014-3 1990 In the groups treated with diltiazem, enalapril, or the combination of both, the drop in arterial blood pressure was 20, 11, and 19 mm Hg for supine diastolic blood pressure (supine DBP): 18, 12, and 19 mm Hg for standing diastolic blood pressure (standing DBP); 22, 20, and 23 mm Hg for supine systolic blood pressure (supine SBP); and 21, 19, and 24 mm Hg for standing systolic blood pressure (standing SBP), respectively. Diltiazem 27-36 selenium binding protein 1 Homo sapiens 405-408 2173313-4 1990 Lisinopril monotherapy in the 1902 patients completing the trial resulted in marked reductions of systolic (SBP) and DBP from 172.5/102.4 mm Hg at baseline to 147.4/86.6 mm Hg by week 8. Lisinopril 0-10 selenium binding protein 1 Homo sapiens 108-111 1974505-10 1990 The patients who received carvedilol in combination with HCTZ and were evaluated for efficacy (n = 38) showed a decrease in SBP/DBP from 156/97 at the end of monotherapy to 145/88 mmHg after 10 weeks; the combination of atenolol with HCTZ (n = 44) reduced BP from 162/97 to 147/88. Carvedilol 26-36 selenium binding protein 1 Homo sapiens 124-127 1974505-10 1990 The patients who received carvedilol in combination with HCTZ and were evaluated for efficacy (n = 38) showed a decrease in SBP/DBP from 156/97 at the end of monotherapy to 145/88 mmHg after 10 weeks; the combination of atenolol with HCTZ (n = 44) reduced BP from 162/97 to 147/88. Hydrochlorothiazide 57-61 selenium binding protein 1 Homo sapiens 124-127 1974505-14 1990 significantly reduced both SBP and DBP over 24 h. The addition of HCTZ led to a further increase in antihypertensive efficacy. Hydrochlorothiazide 66-70 selenium binding protein 1 Homo sapiens 27-30 2290140-13 1990 We conclude that BP and HR levels measured in the laboratory generalizes to real life BP and HR in both men and women and also to real life SBP reactivity in men. Benzo(a)pyrene 17-19 selenium binding protein 1 Homo sapiens 140-143 33797937-10 2021 Positive associations of second-trimester PM2.5 with SBP and DBP percentiles were stronger in children with maternal folate concentrations in the lowest quartile (pinteraction= 0.05 and 0.07, respectively) and associations with DBP percentiles were stronger in female children (pinteraction= 0.05). Folic Acid 117-123 selenium binding protein 1 Homo sapiens 53-56 33810954-7 2021 The seasonal change in SBP was the main responsible for the change in risk estimated with both the UKPDS-Stroke (r2 = 0.43) and the ASCVD (r2 = 0.50) scores, while the change in total cholesterol was the main determinant of the change in risk for the UKPDS-CHD (r2 = 0.34). Cholesterol 184-195 selenium binding protein 1 Homo sapiens 23-26 28835847-10 2017 There was a significant interaction between time and being at goal pre-DCMP for HbA1c, SBP and LDL. Deoxycytidine Monophosphate 71-75 selenium binding protein 1 Homo sapiens 87-90 34900786-2 2021 Therefore, this study aimed to investigate the association between carbohydrate quality index (CQI) and anthropometry, fasting blood glucose (FBG), lipid profile, systolic (SBP), and diastolic (DBP) blood pressure in adults with type 1 diabetes mellitus (T1DM). Carbohydrates 67-79 selenium binding protein 1 Homo sapiens 173-176 34967840-4 2021 We searched online databases using relevant keywords up to April 2021 to identify RCTs using oral L-arginine on systolic (SBP) and diastolic BP (DBP) in adults. Arginine 98-108 selenium binding protein 1 Homo sapiens 122-125 34967840-9 2021 The pooled analysis demonstrated significant decreases in SBP (WMD = -6.40 mmHg; 95%CI: -8.74, -4.05; P<0.001) and DBP (WMD = -2.64 mmHg; 95%CI: -3.94, -1.40; P<0.001) after L-arginine supplementation. Arginine 174-184 selenium binding protein 1 Homo sapiens 58-61 34967840-14 2021 In the nonlinear dose-response analysis, the effective dosage of L-arginine supplementation was detected to be >=4 g/day for SBP (P = 0.034) independent of trial duration. Arginine 65-75 selenium binding protein 1 Homo sapiens 125-128 34856667-13 2021 HR/SBP performed better than the other six parameters for predicting lactate>2 mmol/L, with the AUC of 0.872 and the optimal cutoff value of 1.4 bpm/mmHg (sensitivity 92.1%, specificity 70.9%, P<0.01). Lactic Acid 69-76 selenium binding protein 1 Homo sapiens 3-6 34856667-14 2021 When MBP was greater than or equal to 65 mmHg, MBP x HR, DBP x HR, SBP x HR, HR, HR/SBP, HR/MBP and HR/DBP were significantly correlated with lactate (r= 0.706, 0.705, 0.669, 0.626, 0.555, 0.502, 0.446, all P<0.01). Lactic Acid 142-149 selenium binding protein 1 Homo sapiens 67-70 34856667-14 2021 When MBP was greater than or equal to 65 mmHg, MBP x HR, DBP x HR, SBP x HR, HR, HR/SBP, HR/MBP and HR/DBP were significantly correlated with lactate (r= 0.706, 0.705, 0.669, 0.626, 0.555, 0.502, 0.446, all P<0.01). Lactic Acid 142-149 selenium binding protein 1 Homo sapiens 84-87 34128490-7 2021 CONCLUSIONS: Thiazide-induced changes in serum uric acid or incident hyperuricemia were associated with the achieved SBP/DBP, being lower at the level of 130-139/<90 mm Hg. Thiazides 13-21 selenium binding protein 1 Homo sapiens 117-120 34128490-7 2021 CONCLUSIONS: Thiazide-induced changes in serum uric acid or incident hyperuricemia were associated with the achieved SBP/DBP, being lower at the level of 130-139/<90 mm Hg. Uric Acid 47-56 selenium binding protein 1 Homo sapiens 117-120 34921521-8 2021 In the combined data set plasma sodium level was significantly associated with ECFV (B (SE) = 0.10 (0.04), p = 0.02), and systolic blood pressure (SBP, B (SE) = 0.73 (0.26), p = 0.006), independent of ECFV. Sodium 32-38 selenium binding protein 1 Homo sapiens 147-150 34921521-11 2021 Finally, plasma sodium level is associated with SBP, independent of ECFV and diet. Sodium 16-22 selenium binding protein 1 Homo sapiens 48-51 34798910-6 2021 RESULTS: After adjusting potential confounding factors (age, sex, BMI, height, weight, SBP, DBP, TC, LDL-C, HDL-C, triglycerides, smoking status, alcohol consumption, reflux esophagitis status, hypertension, diabetes, dyslipidemia, ischemic heart disease and cerebrovascular disease), it was revealed that there was a nonlinear relationship between HbA1c and coronary artery calcium score progression, while the scoring point was 5.8%. Calcium 375-382 selenium binding protein 1 Homo sapiens 87-90 24821289-9 2015 After the addition of HCTZ therapy, systolic and diastolic blood pressures (S-BP, D-BP) as well as proteinuria significantly decreased (S-BP: at 6 months, p < 0.05 and 12 months, p < 0.01 vs. 0 month, D-BP: at 12 months, p < 0.05 vs. 0 month, proteinuria: at 6 months, p < 0.05 and 12 months, p < 0.01 vs. 0 month). Hydrochlorothiazide 22-26 selenium binding protein 1 Homo sapiens 76-80 24821289-9 2015 After the addition of HCTZ therapy, systolic and diastolic blood pressures (S-BP, D-BP) as well as proteinuria significantly decreased (S-BP: at 6 months, p < 0.05 and 12 months, p < 0.01 vs. 0 month, D-BP: at 12 months, p < 0.05 vs. 0 month, proteinuria: at 6 months, p < 0.05 and 12 months, p < 0.01 vs. 0 month). Hydrochlorothiazide 22-26 selenium binding protein 1 Homo sapiens 136-140 34285147-7 2021 We then linearly combined the four replicated glycans and found that the glycan score correlated with incident hypertension, SBP and DBP. Polysaccharides 73-79 selenium binding protein 1 Homo sapiens 125-128 34831878-2 2021 We examined the cumulative short-term effect of black carbon (BC) exposure on systolic (SBP) and diastolic (DBP) BP and assessed effect modification by participant characteristics. Carbon 54-60 selenium binding protein 1 Homo sapiens 88-91 34132028-11 2021 Spearman correlation analysis indicated that urinary sodium excretion positively correlated with urinary protein excretion (r = .178, p .001), SBP (r = .109, p = .002), and DBP (r = .086, p = .015). Sodium 53-59 selenium binding protein 1 Homo sapiens 145-148 34716698-6 2021 Bisoprolol was shown to effectively reduce CASP and this effect was directly proportional to the reduction in Br-SBP and of a similar magnitude. Bisoprolol 0-10 selenium binding protein 1 Homo sapiens 113-116 34769545-11 2021 This study suggests that acute consumption of a calamansi-containing ED can positively impact the SBP recovery but not running performance. calamansi 48-57 selenium binding protein 1 Homo sapiens 98-101 34703229-11 2021 The enrichment rate of SPIONs@DFK-SBP-M13 assembly was 13.9 times higher than free SPIONs at 0.5 h, and intracellular Fe content was 3.6 times higher at 1 h. Furthermore, the DFK peptides favored cathepsin B to cleave SPIONs from the M13 templates resulting in release of SPIONs inside cells. Iron 118-120 selenium binding protein 1 Homo sapiens 34-37 34849291-10 2021 CONCLUSION: The study showed the efficacy of Calcium Channel Blocker, Beta Blocker and Angiotensin Receptor Blocker in reduction of SBP & DBP was same, while Calcium Channel Blockers were superior to other two medications. Calcium 45-52 selenium binding protein 1 Homo sapiens 132-135 34579708-7 2021 Pearson correlation coefficients revealed a significant inverse association of total dietary fiber with BMI, SBP, DBP, HbA1c and LDL-C in all participants, participants with and without T2DM (P < 0.05). Dietary Fiber 93-98 selenium binding protein 1 Homo sapiens 109-112 34519016-10 2021 After 12 weeks of cNUT, FMD significantly increased (p < 0.05) and SBP (p = 0.04), total cholesterol and LDL cholesterol (p = 0.03) decreased. cnut 18-22 selenium binding protein 1 Homo sapiens 67-70 34132028-12 2021 After adjusting for age, gender, BMI, eGFR, urinary protein excretion, and history of taking antihypertensive drug, multivariate linear regression demonstrated that higher level of urinary sodium excretion associated with increased level of SBP, DBP, and MAP (beta = 0.020, p = .049; beta = 0.015, p = .040; beta = 0.016, p = .025, respectively). Sodium 189-195 selenium binding protein 1 Homo sapiens 241-244 34257706-9 2021 There was a positive correlation between mean SBP and patient age, comorbid diabetes, and smoking and alcohol habits (p < 0.0001). Alcohols 102-109 selenium binding protein 1 Homo sapiens 46-49 35543419-2 2022 Herein we design and implement bifunctional chimeric biomolecules composed of a solid-binding peptide (SBP) domain that specifically adsorbs onto solid sensor surfaces and a peptide nucleic acid (PNA) moiety that facilitates anchoring of antisense oligonucleotide (ASO) probes for the detection of nucleic acid targets. Oligonucleotides 248-263 selenium binding protein 1 Homo sapiens 80-101 34814506-7 2021 24 h urinary sodium was negatively correlated with age, female, junior high school education or above, and annual family income (P<0.05), and positively correlated with perceived salty taste, BMI and SBP (P<0.05). Sodium 13-19 selenium binding protein 1 Homo sapiens 200-203 34814506-9 2021 The sodium-potassium ratio was negatively correlated with age, female and junior high school education or above annual family income (P<0.05), and positively correlated with perceived salty taste, SBP and eating out 3-5 d/week (P<0.05). Sodium 4-10 selenium binding protein 1 Homo sapiens 197-200 34814506-9 2021 The sodium-potassium ratio was negatively correlated with age, female and junior high school education or above annual family income (P<0.05), and positively correlated with perceived salty taste, SBP and eating out 3-5 d/week (P<0.05). Potassium 11-20 selenium binding protein 1 Homo sapiens 197-200 34266697-9 2021 Genistein intake more than 6 months showed a greater effect on lowering cholesterol -0.76(-1.27, -0.24), SBP (-0.39(-0.70, -0.08)) and DBP -0.40(-0.81, -0.00) and increasing TG and LDL-C. Genistein 0-9 selenium binding protein 1 Homo sapiens 105-108 34266697-10 2021 This meta-analysis provides consistent evidence that genistein intake reduces the CVD risk factors of TC, LDL-C, and SBP significantly. Genistein 53-62 selenium binding protein 1 Homo sapiens 117-120 34194964-7 2021 Replacement of SB with LPA was associated with lower SBP adjusted for wear time (beta = -0.84, p < 0.05), but attenuated after adjustment for age. lpa 23-26 selenium binding protein 1 Homo sapiens 53-56 34140879-11 2021 The tight correlation of SELENBP1 with CCL2 levels provides a novel link between Se metabolism and immune cell activation, with potential relevance for neurological damage and regeneration processes, respectively. Selenium 81-83 selenium binding protein 1 Homo sapiens 25-33 34814473-7 2021 Univariate linear regression analysis showed that salt intake was positively correlated with SBP, DBP, waist circumference and BMI (P<0.05), while multivariate linear regression analysis (adjusted for other factors) only showed a positive correlation between salt intake and BMI (beta=0.053,95%CI: 0.028-0.078, P<0.05). Salts 50-54 selenium binding protein 1 Homo sapiens 93-96 35626560-7 2022 Results revealed that higher SampEn in BP signals was significantly predictive of mortality risk, with an increase of one standard deviation in sBP SampEn and dBP SampEn corresponding to HRs of 1.19 and 1.17, respectively, in models comprehensively controlled for potential confounders. sampen 29-35 selenium binding protein 1 Homo sapiens 144-147 35543419-2 2022 Herein we design and implement bifunctional chimeric biomolecules composed of a solid-binding peptide (SBP) domain that specifically adsorbs onto solid sensor surfaces and a peptide nucleic acid (PNA) moiety that facilitates anchoring of antisense oligonucleotide (ASO) probes for the detection of nucleic acid targets. Oligonucleotides 248-263 selenium binding protein 1 Homo sapiens 103-106 35543419-2 2022 Herein we design and implement bifunctional chimeric biomolecules composed of a solid-binding peptide (SBP) domain that specifically adsorbs onto solid sensor surfaces and a peptide nucleic acid (PNA) moiety that facilitates anchoring of antisense oligonucleotide (ASO) probes for the detection of nucleic acid targets. Oligonucleotides, Antisense 265-268 selenium binding protein 1 Homo sapiens 80-101 35543419-2 2022 Herein we design and implement bifunctional chimeric biomolecules composed of a solid-binding peptide (SBP) domain that specifically adsorbs onto solid sensor surfaces and a peptide nucleic acid (PNA) moiety that facilitates anchoring of antisense oligonucleotide (ASO) probes for the detection of nucleic acid targets. Oligonucleotides, Antisense 265-268 selenium binding protein 1 Homo sapiens 103-106 35543419-7 2022 The dual nature of the chimeric construct is highly amenable to a variety of platforms allowing for both specific recognition and probe immobilization on the sensor surface, while the modular design of the solid-binding peptide-antisense oligonucleotide provides facile functionalization of a wide diversity of solid substrates. Oligonucleotides 238-253 selenium binding protein 1 Homo sapiens 206-227 35313679-5 2022 Baseline serum phosphate was associated with age, BMI, waist circumference, SBP, total calcium, bicarbonate, and total cholesterol in women. Phosphates 15-24 selenium binding protein 1 Homo sapiens 76-79 35391843-5 2022 Results: At 1 month, empagliflozin 10 mg decreased 24-h systolic (SBP) and diastolic (DBP) BP significantly by -5 +- 7 mmHg (p < 0.001) and -2 +- 6 mmHg (p = 0.03). empagliflozin 21-34 selenium binding protein 1 Homo sapiens 66-69 35524894-9 2022 The change in sBP during the month (DeltasBP) correlated with the change in serum Cl (DeltaCl) (P = 0.012) but not with the change in serum Na. cl (deltacl) 82-94 selenium binding protein 1 Homo sapiens 14-17 35571211-4 2022 A unit per km2 rise in alcohol outlet density in 400 m buffering area was related to a rise in waist circumference (1.45 mm, 95% CI: 0.13, 2.77), SBP (0.29 mmHg, 95% CI: 0.09, 0.49), and DBP (0.19 mmHg, 95% CI: 0.03, 0.35). Alcohols 23-30 selenium binding protein 1 Homo sapiens 146-149 35571211-5 2022 A unit per 100 m rise in distance to the closest alcohol outlet was related to a rise in waist circumference (-2.39 mm, 95% CI: -4.18, -0.59), SBP (-0.41 mmHg, 95% CI: -0.68, -0.15), and DBP (-0.29 mmHg, 95% CI: -0.51, -0.07). Alcohols 49-56 selenium binding protein 1 Homo sapiens 143-146 35348158-5 2022 The charge transfer character is more pronounced in meta-methoxy substituted antimony(V) derivatives (SbDMP(OMe)2 PF6, SbTMP(OMe)2 PF6) than the para-methoxy or no-methoxy substituted antimony(V) derivatives (SbP(OMe)2 PF6, SbMP(OMe)2 PF6). meta-methoxy substituted antimony 52-85 selenium binding protein 1 Homo sapiens 209-212 35348158-5 2022 The charge transfer character is more pronounced in meta-methoxy substituted antimony(V) derivatives (SbDMP(OMe)2 PF6, SbTMP(OMe)2 PF6) than the para-methoxy or no-methoxy substituted antimony(V) derivatives (SbP(OMe)2 PF6, SbMP(OMe)2 PF6). sbtmp(ome)2 pf6 119-134 selenium binding protein 1 Homo sapiens 209-212 35385506-8 2022 In the fully adjusted model, treatment with IV hydralazine led to 13 (-15.9, -10.1), 18 (-22.2, -14) and 11 (-14.1, -8.3) mmHg lower MAP, SBP, and DBP in the 6 hours following severe HTN development compared to no treatment. Hydralazine 47-58 selenium binding protein 1 Homo sapiens 138-141 35234352-7 2022 RESULTS: Patients with CMBs had a significant higher nocturnal mean SBP and lower relative nocturnal SBP dipping rate. cmbs 23-27 selenium binding protein 1 Homo sapiens 68-71 35234352-7 2022 RESULTS: Patients with CMBs had a significant higher nocturnal mean SBP and lower relative nocturnal SBP dipping rate. cmbs 23-27 selenium binding protein 1 Homo sapiens 101-104 35234352-9 2022 In model 1, higher nocturnal mean SBP positively correlated with presence of CMBs (standardized beta = 0.254, odds ratio (OR) = 1.029, p = .041). cmbs 77-81 selenium binding protein 1 Homo sapiens 34-37 35234352-10 2022 In model 2, the relative nocturnal SBP dipping rate was negatively correlated with CMBs (standardized beta = -.363, OR = 0.918, p = .007). cmbs 83-87 selenium binding protein 1 Homo sapiens 35-38 35234352-11 2022 Only patients with deep CMBs had significant higher nocturnal mean SBP and lower relative nocturnal SBP dipping rate in comparison with those without CMBs. cmbs 24-28 selenium binding protein 1 Homo sapiens 67-70 35234352-11 2022 Only patients with deep CMBs had significant higher nocturnal mean SBP and lower relative nocturnal SBP dipping rate in comparison with those without CMBs. cmbs 24-28 selenium binding protein 1 Homo sapiens 100-103 35234352-11 2022 Only patients with deep CMBs had significant higher nocturnal mean SBP and lower relative nocturnal SBP dipping rate in comparison with those without CMBs. cmbs 150-154 selenium binding protein 1 Homo sapiens 100-103 35234352-12 2022 CONCLUSIONS: Higher nocturnal SBP and lower relative nocturnal SBP dipping rate may be associated with CMBs in hypertensive patients. cmbs 103-107 selenium binding protein 1 Homo sapiens 30-33 35234352-12 2022 CONCLUSIONS: Higher nocturnal SBP and lower relative nocturnal SBP dipping rate may be associated with CMBs in hypertensive patients. cmbs 103-107 selenium binding protein 1 Homo sapiens 63-66 35258018-9 2022 In obese cases, there was a statistically significant correlation between LVMI and 24-h SBP SDS, daytime SBP SDS, 24-h SBP load, daytime SBP load as well as nighttime SBP SDS and nighttime SBP load. Sodium Dodecyl Sulfate 171-174 selenium binding protein 1 Homo sapiens 167-170 35258018-10 2022 When the whole group was evaluated, 24-h SBP SDS was the most effective parameter influencing LVMI (P = 0.001). Sodium Dodecyl Sulfate 45-48 selenium binding protein 1 Homo sapiens 41-44 35258018-9 2022 In obese cases, there was a statistically significant correlation between LVMI and 24-h SBP SDS, daytime SBP SDS, 24-h SBP load, daytime SBP load as well as nighttime SBP SDS and nighttime SBP load. Sodium Dodecyl Sulfate 92-95 selenium binding protein 1 Homo sapiens 88-91 35258018-11 2022 Similarly, the most effective ABPM parameter on LVMI in obese patients was 24-h SBP SDS (P = 0.001). Sodium Dodecyl Sulfate 84-87 selenium binding protein 1 Homo sapiens 80-83 35227313-6 2022 Compared to Telmisartan80, Telmisartan40/S-Amlodipine2.5 showed significantly better reductions in 24-h mean SBP and DBP after 8 weeks. telmisartan40 27-40 selenium binding protein 1 Homo sapiens 109-112 35038932-9 2022 Second, the increase in SBP was associated with a combination of the two risk factors, >=2h screen time/low CRF was associated with a 7% increase in elevated SBP (p = 0.025). Deuterium 89-91 selenium binding protein 1 Homo sapiens 24-27 35038932-9 2022 Second, the increase in SBP was associated with a combination of the two risk factors, >=2h screen time/low CRF was associated with a 7% increase in elevated SBP (p = 0.025). Deuterium 89-91 selenium binding protein 1 Homo sapiens 158-161 35232417-10 2022 In the simple sugar based pattern, we observed a significant association for SBP, DBP, and triglyceride (TG) levels. Triglycerides 91-103 selenium binding protein 1 Homo sapiens 77-80 35232417-10 2022 In the simple sugar based pattern, we observed a significant association for SBP, DBP, and triglyceride (TG) levels. Triglycerides 105-107 selenium binding protein 1 Homo sapiens 77-80 35227313-6 2022 Compared to Telmisartan80, Telmisartan40/S-Amlodipine2.5 showed significantly better reductions in 24-h mean SBP and DBP after 8 weeks. s-amlodipine2 41-54 selenium binding protein 1 Homo sapiens 109-112 34686640-10 2022 ETCO2(AUROC of 0.67 CI 0.63-0.71) was better in predicting mortality than shock index(SI)(AUROC 0.55 CI 0.50-0.60) and systolic blood pressure(SBP)(AUROC 0.58 CI 0.53-0.62)p < 0.0005. etco2 0-5 selenium binding protein 1 Homo sapiens 143-146 35142521-3 2022 Surprisingly, we found that removal of polyhistidines, a common tag for protein purification, dramatically decrease the binding affinity of a SBP-tagged nanobody onto a silica surface. polyhistidine 39-53 selenium binding protein 1 Homo sapiens 142-145 35142521-3 2022 Surprisingly, we found that removal of polyhistidines, a common tag for protein purification, dramatically decrease the binding affinity of a SBP-tagged nanobody onto a silica surface. Silicon Dioxide 169-175 selenium binding protein 1 Homo sapiens 142-145 35142521-7 2022 Guided by physical insights, the work provides a simple strategy that can dramatically improve affinity between a SBP and a silica surface, promising a new way for controllable immobilization of proteins, as demonstrated using nanobodies. Silicon Dioxide 124-130 selenium binding protein 1 Homo sapiens 114-117 34267072-8 2022 Serum disulphide concentration positively correlated with 24-h SBP, and 24-h DBP. disulphide 6-16 selenium binding protein 1 Homo sapiens 63-66 34779388-7 2022 However, the concentration of free vitamin D was independently associated with SBP (95% CI -2.691 ~ -0.210; p = 0.022) (Table 3), but not with DBP (95% CI -0.934 ~ 0.285; p = 0.293). Vitamin D 35-44 selenium binding protein 1 Homo sapiens 79-82 35127846-9 2021 Combining the predictability of the LVEF to the determinant role of SBP/PEP on the Ees variations, we obtained: (SBP*LVEF)/PEP mm Hg/ms, with an improved R 2 value (R 2 = 0.848; P < 0.001). ees 83-86 selenium binding protein 1 Homo sapiens 68-71 35127846-9 2021 Combining the predictability of the LVEF to the determinant role of SBP/PEP on the Ees variations, we obtained: (SBP*LVEF)/PEP mm Hg/ms, with an improved R 2 value (R 2 = 0.848; P < 0.001). ees 83-86 selenium binding protein 1 Homo sapiens 113-116 35087571-11 2021 Methylation levels of cg14228300 and cg04812164 were associated with SBP. cg14228300 22-32 selenium binding protein 1 Homo sapiens 69-72 35128285-6 2022 Here, we investigate conformational states and dynamics in the cluster A-I SBP AztC fromParacoccus denitrificans, characterizing its unusual intrinsic fluorescence behavior and thermodynamics of zinc binding. aztc 79-83 selenium binding protein 1 Homo sapiens 75-78 34906037-5 2022 Multivariable linear regression models were calculated to assess the associations between CTQ, systolic and diastolic blood pressure, renin and aldosterone concentrations and the ratio of aldosterone and systolic blood pressure (A/SBP). Aldosterone 188-199 selenium binding protein 1 Homo sapiens 231-234 35087877-5 2021 In the hypertension non-treatment group, the associations between UA and BP including SBP, DBP were both an inverted U-shape. Uric Acid 66-68 selenium binding protein 1 Homo sapiens 86-89 35087571-11 2021 Methylation levels of cg14228300 and cg04812164 were associated with SBP. cg04812164 37-47 selenium binding protein 1 Homo sapiens 69-72 35087877-12 2021 In the hypertension non-treatment group, the associations between UA and BP including SBP and DBP were both an inverted U-shape. Uric Acid 66-68 selenium binding protein 1 Homo sapiens 86-89 2697728-7 1989 The mean BP fall [systolic (SBP)/diastolic (DBP), measured in mmHg] just before drug intake was significantly greater with benazepril: -14/-9 (10 mg o.d. benazepril 123-133 selenium binding protein 1 Homo sapiens 28-31 34997324-9 2022 Malondialdehyde could act as a mediator between exposure to 1-HydroxyPyrene and increase in fast blood sugar, exposure to 2-HydroxyNaphthalene and increase in systolic blood pressure and exposure to 2-HydroxyFluorene and increase in SBP. Malondialdehyde 0-15 selenium binding protein 1 Homo sapiens 233-236 2808412-1 1989 The amino acid sequence of the sex steroid-binding protein (SBP or SHBG) of rabbit serum, specific for binding testosterone and 5 alpha-dihydrotestosterone, was determined using a complementary combination of mass spectrometric and Edman degradation techniques. Dihydrotestosterone 128-155 selenium binding protein 1 Homo sapiens 60-63 2532567-6 1989 After injecting NaCl, an increase occurred in SBP (20%), DBP (25%), HR (10%) and in depth of breathing. Sodium Chloride 16-20 selenium binding protein 1 Homo sapiens 46-49 2808412-1 1989 The amino acid sequence of the sex steroid-binding protein (SBP or SHBG) of rabbit serum, specific for binding testosterone and 5 alpha-dihydrotestosterone, was determined using a complementary combination of mass spectrometric and Edman degradation techniques. Steroids 35-42 selenium binding protein 1 Homo sapiens 60-63 2808412-1 1989 The amino acid sequence of the sex steroid-binding protein (SBP or SHBG) of rabbit serum, specific for binding testosterone and 5 alpha-dihydrotestosterone, was determined using a complementary combination of mass spectrometric and Edman degradation techniques. Testosterone 111-123 selenium binding protein 1 Homo sapiens 60-63 2533220-5 1989 Zofenopril also decreased ANP levels in a manner directly related to peripheral venodilatation (r = .64; P less than .05) and modified arginine-vasopressin (AVP) proportionally to the fall in blood pressure observed in response to drug administration (%SBP/%AVP: r = .64, P less than .05; %DBP/%AVP: r = .67, P less than .05). zofenopril 0-10 selenium binding protein 1 Homo sapiens 253-256 2795592-8 1989 Confirming this finding significantly lower tyramine doses were required to produce the same SBP increase in hypertensives than in the normotensive volunteers. Tyramine 44-52 selenium binding protein 1 Homo sapiens 93-96 2637953-7 1989 In the thiopentone group, SBP decreased after induction and tracheal intubation was followed by a significant increase of SBP and HR. Thiopental 7-18 selenium binding protein 1 Homo sapiens 26-29 2637953-8 1989 In the propofol group, both SBP and HR decreased after induction and tracheal intubation was also followed by an increase of SBP and HR. Propofol 7-15 selenium binding protein 1 Homo sapiens 28-31 2550642-7 1989 The larger fall in SBP with lisinopril was statistically significant (lying SBP, P = 0.01; standing SBP, P = 0.0001). Lisinopril 28-38 selenium binding protein 1 Homo sapiens 19-22 2475674-1 1989 A very close similarity in molecular, steroid-binding and immunological properties have been demonstrated for the sex steroid-binding proteins of plasma from human (hSBP) and monkey (mSBP): both are glycoproteins composed of two similar subunits able to bind one steroid molecule and to cross-react with the same antibodies. Steroids 118-125 selenium binding protein 1 Homo sapiens 165-169 2475674-1 1989 A very close similarity in molecular, steroid-binding and immunological properties have been demonstrated for the sex steroid-binding proteins of plasma from human (hSBP) and monkey (mSBP): both are glycoproteins composed of two similar subunits able to bind one steroid molecule and to cross-react with the same antibodies. Steroids 118-125 selenium binding protein 1 Homo sapiens 165-169 2510664-10 1989 The decline in both SBP and DBP with diltiazem was significantly related to their control values (r = 0.31 and 0.28 respectively, p less than 0.0001 for both). Diltiazem 37-46 selenium binding protein 1 Homo sapiens 20-23 2672065-5 1989 The effects of caffeine on SBP and HR were contingent on the experimental condition such that the difference in SBP and HR between the high vs low dose of caffeine was significant only under the caffeine plus psychological stress condition. Caffeine 15-23 selenium binding protein 1 Homo sapiens 27-30 2672065-5 1989 The effects of caffeine on SBP and HR were contingent on the experimental condition such that the difference in SBP and HR between the high vs low dose of caffeine was significant only under the caffeine plus psychological stress condition. Caffeine 15-23 selenium binding protein 1 Homo sapiens 112-115 2672065-5 1989 The effects of caffeine on SBP and HR were contingent on the experimental condition such that the difference in SBP and HR between the high vs low dose of caffeine was significant only under the caffeine plus psychological stress condition. Caffeine 155-163 selenium binding protein 1 Homo sapiens 27-30 2672065-5 1989 The effects of caffeine on SBP and HR were contingent on the experimental condition such that the difference in SBP and HR between the high vs low dose of caffeine was significant only under the caffeine plus psychological stress condition. Caffeine 155-163 selenium binding protein 1 Homo sapiens 112-115 2672065-5 1989 The effects of caffeine on SBP and HR were contingent on the experimental condition such that the difference in SBP and HR between the high vs low dose of caffeine was significant only under the caffeine plus psychological stress condition. Caffeine 155-163 selenium binding protein 1 Homo sapiens 27-30 2672065-5 1989 The effects of caffeine on SBP and HR were contingent on the experimental condition such that the difference in SBP and HR between the high vs low dose of caffeine was significant only under the caffeine plus psychological stress condition. Caffeine 155-163 selenium binding protein 1 Homo sapiens 112-115 2550642-7 1989 The larger fall in SBP with lisinopril was statistically significant (lying SBP, P = 0.01; standing SBP, P = 0.0001). Lisinopril 28-38 selenium binding protein 1 Homo sapiens 76-79 2550642-7 1989 The larger fall in SBP with lisinopril was statistically significant (lying SBP, P = 0.01; standing SBP, P = 0.0001). Lisinopril 28-38 selenium binding protein 1 Homo sapiens 76-79 2813476-3 1989 The most striking finding was that, in men, but not in women, total serum cholesterol was significantly positively correlated with SBP in all conditions (LDL and HDL cholesterol followed the same pattern). Cholesterol 74-85 selenium binding protein 1 Homo sapiens 131-134 2813476-3 1989 The most striking finding was that, in men, but not in women, total serum cholesterol was significantly positively correlated with SBP in all conditions (LDL and HDL cholesterol followed the same pattern). Cholesterol 166-177 selenium binding protein 1 Homo sapiens 131-134 2491521-2 1989 The treated with calcium showed a significant decrease in blood pressure (BP), the maximal reduction being of 6 mm Hg in the systolic pressure (SBP) and 3 mm in the diastolic (DBP) at the end of the 8th week. Calcium 17-24 selenium binding protein 1 Homo sapiens 144-147 2566391-4 1989 Similarly, fentanyl decreased the systolic (SBP), mean (MBP) and diastolic blood pressures (DBP) significantly below the baseline, while these pressures were either retained at or elevated slightly above control in the esmolol group. Fentanyl 11-19 selenium binding protein 1 Homo sapiens 44-47 2672266-5 1989 The circulating testosterone is, for the most part, bound to proteins and especially a protein having a strong affinity for testosterone and estradiol, the testosterone estradiol binding-protein (TeBG) or sex steroid binding-protein (SBP). Testosterone 16-28 selenium binding protein 1 Homo sapiens 234-237 2660993-3 1989 After 1 week, nicardipine induced a significant blood pressure reduction (p less than 0.01), with a decrease in mean SBP/DBP values of -15/-11 mmHg (from baseline values of 165/104 to 150/93 mmHg) in supine and of -16/-12 mmHg (from 158/110 to 142/98 mmHg) in standing position. Nicardipine 14-25 selenium binding protein 1 Homo sapiens 117-120 2921100-6 1989 During atenolol, the reduction in SBP was close to statistical significance, HR and S-T were significantly reduced (p less than or equal to 0.05) whereas TWL was significantly increased (p less than or equal to 0.05). Atenolol 7-15 selenium binding protein 1 Homo sapiens 34-37 2666139-6 1989 SR-Nicardipine significantly reduced systolic (SBP) and diastolic (DBP) blood pressure at each time after dosing. sr-nicardipine 0-14 selenium binding protein 1 Homo sapiens 47-50 2657058-4 1989 Nifedipine produced a greater orthostatic effect, and hence a significantly greater fall in erect SBP than felodipine (P less than 0.05). Nifedipine 0-10 selenium binding protein 1 Homo sapiens 98-101 2475683-7 1989 In conclusion, verapamil SR seems useful to obtain a constant and significant reduction of 24-h blood pressure values with a significant reduction of SBP and DBP variability. Verapamil 15-27 selenium binding protein 1 Homo sapiens 150-153 2591463-8 1989 A comparison of alfuzosin 5 mg, prazosin 1 mg and placebo each administered for 4 days, indicated that alfuzosin did not significantly reduce standing SBP on either Day 1 or Day 4; prazosin reduced SBP at 2 and 4 h on Day 1 and 6 h on Day 4 compared to placebo. Prazosin 181-189 selenium binding protein 1 Homo sapiens 198-201 2591463-4 1989 In the standing position, SBP was reduced at 2 and 4 h with 5 mg alfuzosin; significant increases in HR occurred following 1, 2.5 and 5 mg at 2, 4, 6 and 8 h after administration. alfuzosin 65-74 selenium binding protein 1 Homo sapiens 26-29 3181436-4 1988 Peptide mapping analyses of the SBP subfractions showed similar patterns, with some differences which might in part be due to the existence of an N-linked carbohydrate chain. n-linked carbohydrate 146-167 selenium binding protein 1 Homo sapiens 32-35 3066270-12 1988 was marked after placebo and significantly decreased after labetalol with a reduction of 52% for SBP and 49% for DBP (p less than 0.001). Labetalol 59-68 selenium binding protein 1 Homo sapiens 97-100 3241258-4 1988 The urinary sodium to potassium ratio was significantly and positively correlated with SBP and DBP in both males and females. Sodium 12-18 selenium binding protein 1 Homo sapiens 87-90 3241258-4 1988 The urinary sodium to potassium ratio was significantly and positively correlated with SBP and DBP in both males and females. Potassium 22-31 selenium binding protein 1 Homo sapiens 87-90 3241258-5 1988 Urinary sodium was weakly and positively correlated with SBP only in the north. Sodium 8-14 selenium binding protein 1 Homo sapiens 57-60 3241258-8 1988 Urinary calcium (creatinine) was negatively correlated with SBP in males, and with SBP and DBP in the south. Calcium 8-15 selenium binding protein 1 Homo sapiens 60-63 3241258-8 1988 Urinary calcium (creatinine) was negatively correlated with SBP in males, and with SBP and DBP in the south. Calcium 8-15 selenium binding protein 1 Homo sapiens 83-86 3241258-8 1988 Urinary calcium (creatinine) was negatively correlated with SBP in males, and with SBP and DBP in the south. Creatinine 17-27 selenium binding protein 1 Homo sapiens 60-63 3241258-8 1988 Urinary calcium (creatinine) was negatively correlated with SBP in males, and with SBP and DBP in the south. Creatinine 17-27 selenium binding protein 1 Homo sapiens 83-86 3241258-9 1988 Urinary potassium was negatively correlated with SBP and DBP only in the 20-29 year age group. Potassium 8-17 selenium binding protein 1 Homo sapiens 49-52 2560512-0 1989 Regulation of SBP synthesis in human cancer cell lines by steroid and thyroid hormones. Steroids 58-65 selenium binding protein 1 Homo sapiens 14-17 2560512-1 1989 The presence of human sex steroid binding protein (SBP) in liver cells, the supposed site of SBP synthesis, and in other target cells for sex steroid hormones such as breast, endometrium and prostate epithelium, have been demonstrated by indirect immunofluorescence. Steroids 142-158 selenium binding protein 1 Homo sapiens 51-54 2560512-4 1989 It was only found in hepatoma cells where it is regulated by estradiol, antiestrogen tamoxifen and triiodothyronine, in a similar way as secreted SBP. Estradiol 61-70 selenium binding protein 1 Homo sapiens 146-149 2560512-4 1989 It was only found in hepatoma cells where it is regulated by estradiol, antiestrogen tamoxifen and triiodothyronine, in a similar way as secreted SBP. Tamoxifen 85-94 selenium binding protein 1 Homo sapiens 146-149 2560512-4 1989 It was only found in hepatoma cells where it is regulated by estradiol, antiestrogen tamoxifen and triiodothyronine, in a similar way as secreted SBP. Triiodothyronine 99-115 selenium binding protein 1 Homo sapiens 146-149 3250038-0 1988 Role of SBP evaluation to better understand the tamoxifen-induced changes of endocrine milieu. Tamoxifen 48-57 selenium binding protein 1 Homo sapiens 8-11 3236318-4 1988 Nitrendipine 20 mg once daily significantly reduced supine and standing SBP and standing DBP (supine 150/97, standing 148/98 mmHg), but on 20 mg twice daily only supine SBP was significantly reduced (supine 150/99, standing 151/106 mmHg). Nitrendipine 0-12 selenium binding protein 1 Homo sapiens 72-75 3138103-1 1988 Sex steroid-binding protein (SBP) is a plasma glycoprotein which, in man and many other mammals, binds significant amounts of circulating testosterone (T) with high affinity. Testosterone 138-150 selenium binding protein 1 Homo sapiens 29-32 3138103-4 1988 Castrates implanted with identical T capsules but infused with human (h) SBP at a rate that produced a steady state plasma hSBP concentration of 75 nM, had markedly higher plasma T concentrations (3.44 +/- 0.32 ng/ml); however, circulating LH and FSH concentrations were not significantly different from those of the vehicle-infused controls. Luteinizing Hormone 240-242 selenium binding protein 1 Homo sapiens 73-76 3142403-6 1988 In the multivariate analysis including age and body mass index (BMI), the consumption of 40 ml of alcohol from beer was associated with an increase of 5.7 mmHg for SBP and 2.6 mmHg for DBP (p less than 0.001). Alcohols 98-105 selenium binding protein 1 Homo sapiens 164-167 3271611-14 1988 INDO had no effect on the magnitude of the pressure rise with PE, but decreased the threshold dose for effects on SBP. indo 0-4 selenium binding protein 1 Homo sapiens 114-117 3167126-1 1988 The role of the carbohydrate component of sex steroid-binding globulin (SBP) from human blood in the glycoprotein interaction with the recognition system for SBP-estrogen complexes in human decidual endometrium plasma membrane was studied. Carbohydrates 16-28 selenium binding protein 1 Homo sapiens 72-75 3167126-1 1988 The role of the carbohydrate component of sex steroid-binding globulin (SBP) from human blood in the glycoprotein interaction with the recognition system for SBP-estrogen complexes in human decidual endometrium plasma membrane was studied. Carbohydrates 16-28 selenium binding protein 1 Homo sapiens 158-161 3167126-1 1988 The role of the carbohydrate component of sex steroid-binding globulin (SBP) from human blood in the glycoprotein interaction with the recognition system for SBP-estrogen complexes in human decidual endometrium plasma membrane was studied. Steroids 46-53 selenium binding protein 1 Homo sapiens 72-75 3167126-1 1988 The role of the carbohydrate component of sex steroid-binding globulin (SBP) from human blood in the glycoprotein interaction with the recognition system for SBP-estrogen complexes in human decidual endometrium plasma membrane was studied. Steroids 46-53 selenium binding protein 1 Homo sapiens 158-161 3167126-2 1988 It was shown that the removal of N-acetylneuraminic acid residues from the oligosaccharide chains of SBP did not affect the steroid-binding or immunochemical properties of the glycoprotein. Oligosaccharides 75-90 selenium binding protein 1 Homo sapiens 101-104 3167126-4 1988 It is concluded that the oligosaccharide chains of SBP are involved in the formation of determinants needed for recognition of the SBP-estrogen complexes by endometrium cell plasma membranes. Oligosaccharides 25-40 selenium binding protein 1 Homo sapiens 51-54 3167126-4 1988 It is concluded that the oligosaccharide chains of SBP are involved in the formation of determinants needed for recognition of the SBP-estrogen complexes by endometrium cell plasma membranes. Oligosaccharides 25-40 selenium binding protein 1 Homo sapiens 131-134 2841595-3 1988 SBP-binding activity is increased after treatment of cells with tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA). Tetradecanoylphorbol Acetate 79-115 selenium binding protein 1 Homo sapiens 0-3 2969743-7 1988 In contrast, in 92% of the patients with a SBP during CEI greater than 160 mmHg, PTRA was not successful. ptra 81-85 selenium binding protein 1 Homo sapiens 43-46 2841595-3 1988 SBP-binding activity is increased after treatment of cells with tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA). Tetradecanoylphorbol Acetate 117-120 selenium binding protein 1 Homo sapiens 0-3 2841595-4 1988 The essential increase in a number of metaphases with chromosome endoreduplications in TPA-treated lymphocytes indicates that SBP may be involved in initiation of chromosome replication or in alteration of the mitotic spindle function. Tetradecanoylphorbol Acetate 87-90 selenium binding protein 1 Homo sapiens 126-129 3142652-0 1988 [Identification of a photolabelled site of the plasma binding protein for testosterone and estradiol (SBP) using tritiated 17 beta-hydroxy- 4,6-androstadien-3-one]. Testosterone 74-86 selenium binding protein 1 Homo sapiens 102-105 2847619-5 1988 In the children with a normal testosterone (T) rise, plasma SBP decreased (% of basal values) either significantly (38.3 +/- 9.3%, group A; n = 29), or moderately (13.4 +/- 4.4%, group B; n = 9) or did not change (-1.6 +/- 6.4%, group C; n = 10). Testosterone 30-42 selenium binding protein 1 Homo sapiens 60-63 2847619-11 1988 However, the lowering effect of ACTH on SBP levels is likely mediated by glucocorticoids, since its effect was reproduced by high doses (8 mg/day for 3 days) of dexamethasone given at once or after 3 days of treatment at lower dose (20 micrograms/kg BW). Dexamethasone 161-174 selenium binding protein 1 Homo sapiens 40-43 3142652-0 1988 [Identification of a photolabelled site of the plasma binding protein for testosterone and estradiol (SBP) using tritiated 17 beta-hydroxy- 4,6-androstadien-3-one]. Estradiol 91-100 selenium binding protein 1 Homo sapiens 102-105 3142652-0 1988 [Identification of a photolabelled site of the plasma binding protein for testosterone and estradiol (SBP) using tritiated 17 beta-hydroxy- 4,6-androstadien-3-one]. beta-hydroxy- 4,6-androstadien-3-one 126-162 selenium binding protein 1 Homo sapiens 102-105 3440663-2 1987 The percentage of saturated fatty acids (FA) in AT was directly correlated with systolic (SBP) and diastolic (DBP) blood pressure (p less than 0.01). Fatty Acids 18-39 selenium binding protein 1 Homo sapiens 90-93 3142652-1 1988 The testosterone-estradiol binding protein (sex binding protein = SBP), immunopurified from human placental blood, was photolabelled by irradiation at lambda greater than 300 mm in the presence of tritiated 17 beta-hydroxy-androsta-4,6-dien-3-one. 6-dehydrotestosterone 207-246 selenium binding protein 1 Homo sapiens 66-69 2906874-4 1988 The ketanserin/beta-blocker combination decreased mean sitting systolic/diastolic blood pressure (SBP/DBP) from 169/107 mmHg to 156/91 mmHg at the end of the 12-week active treatment period. Ketanserin 4-14 selenium binding protein 1 Homo sapiens 98-101 2906874-7 1988 The ketanserin/diuretic combination led to a significant reduction in mean SBP/DBP from 164/106 mmHg to 146/92 mmHg after 12 weeks, with no significant change in heart rate. Ketanserin 4-14 selenium binding protein 1 Homo sapiens 75-78 3056187-1 1988 In humans, sex steroid-binding protein (SBP) is a protein from the liver which binds with high affinity sex steroid hormones. Steroids 108-124 selenium binding protein 1 Homo sapiens 40-43 3333530-6 1987 For both systolic (SBP) and diastolic (DBP) blood pressure, change in polyunsaturated fatty acid intake was the strongest dietary predictor of BP change. Fatty Acids, Unsaturated 70-96 selenium binding protein 1 Homo sapiens 19-22 2949473-6 1987 It was suggested that the decrease of SBP in puberty might be largely influenced by alteration in the hormonal balance of testosterone, oestradiol and dehydroepiandrosterone. Testosterone 122-134 selenium binding protein 1 Homo sapiens 38-41 3117438-5 1987 It is suggested that SBP could act to sequester the sex steroid hormones in amniotic fluid. Steroids 56-72 selenium binding protein 1 Homo sapiens 21-24 3330992-6 1987 For N, but not H, there was a positive correlation between age and the magnitude in reduction of SBP (r = 0.79; p less than 0.005), but not for DPB. Nitrogen 4-5 selenium binding protein 1 Homo sapiens 97-100 3499244-11 1987 PROP was associated with the most decrease in SBP and DBP and in addition respiratory depression (p less than 0.05). Propofol 0-4 selenium binding protein 1 Homo sapiens 46-49 2949473-6 1987 It was suggested that the decrease of SBP in puberty might be largely influenced by alteration in the hormonal balance of testosterone, oestradiol and dehydroepiandrosterone. Estradiol 136-146 selenium binding protein 1 Homo sapiens 38-41 2949473-6 1987 It was suggested that the decrease of SBP in puberty might be largely influenced by alteration in the hormonal balance of testosterone, oestradiol and dehydroepiandrosterone. Dehydroepiandrosterone 151-173 selenium binding protein 1 Homo sapiens 38-41 3331377-5 1987 (2) Danazol is a progestagen with high affinity for sex steroid-binding protein (SBP); when given in high dosages in normal males, it increased rapidly the dialyzable fraction (percent protein unbound or free fraction) of T. This suggests that by interacting with the binding sites of SBP, danazol and/or its metabolites displace the fraction of T bound to SBP. Danazol 4-11 selenium binding protein 1 Homo sapiens 81-84 3331377-5 1987 (2) Danazol is a progestagen with high affinity for sex steroid-binding protein (SBP); when given in high dosages in normal males, it increased rapidly the dialyzable fraction (percent protein unbound or free fraction) of T. This suggests that by interacting with the binding sites of SBP, danazol and/or its metabolites displace the fraction of T bound to SBP. Danazol 4-11 selenium binding protein 1 Homo sapiens 285-288 3331377-5 1987 (2) Danazol is a progestagen with high affinity for sex steroid-binding protein (SBP); when given in high dosages in normal males, it increased rapidly the dialyzable fraction (percent protein unbound or free fraction) of T. This suggests that by interacting with the binding sites of SBP, danazol and/or its metabolites displace the fraction of T bound to SBP. Danazol 4-11 selenium binding protein 1 Homo sapiens 285-288 3331377-6 1987 However, in males as well as in females, the long-term administration of danazol decreased also the binding capacity of SBP, and consequently increased the free fraction of sex steroid hormones. Danazol 73-80 selenium binding protein 1 Homo sapiens 120-123 3331377-7 1987 (3) Dihydrotestosterone (DHT), the most active androgen in many target cells, given at therapeutic dosages to adult males, resulted in a decrease in plasma concentrations of luteinizing hormone (LH) and T, without any significant change in the percent of free T, even though the affinity of DHT for SBP is higher than that of T. This suggests that the main effect of DHT is to inhibit gonadotropin secretion at the central level. Dihydrotestosterone 4-23 selenium binding protein 1 Homo sapiens 299-302 3331377-7 1987 (3) Dihydrotestosterone (DHT), the most active androgen in many target cells, given at therapeutic dosages to adult males, resulted in a decrease in plasma concentrations of luteinizing hormone (LH) and T, without any significant change in the percent of free T, even though the affinity of DHT for SBP is higher than that of T. This suggests that the main effect of DHT is to inhibit gonadotropin secretion at the central level. Dihydrotestosterone 25-28 selenium binding protein 1 Homo sapiens 299-302 2430418-1 1986 The serum concentration of sex-steroid-binding plasma protein (SBP) was measured with radioimmunoassay for 92 patients with Graves" disease, 36 males and 56 females, as well as 92 age- and sex-matched controls. Steroids 31-38 selenium binding protein 1 Homo sapiens 63-66 2826889-4 1987 The intracellular localization of h-SBP indicate that h-SBP could be taken up from the extracellular compartment or synthesized in situ in sex steroid target organs, where it may play a role in hormone uptake. Steroids 143-150 selenium binding protein 1 Homo sapiens 34-39 2826889-4 1987 The intracellular localization of h-SBP indicate that h-SBP could be taken up from the extracellular compartment or synthesized in situ in sex steroid target organs, where it may play a role in hormone uptake. Steroids 143-150 selenium binding protein 1 Homo sapiens 54-59 2826889-5 1987 The hormonal regulation of h-SBP secretion by a human hepatoma cell line, H5A, showed that tri-iodothyronine was more potent than estradiol or tamoxifen, which acted as estrogen agonist, in increasing secreted h-SBP and the combined effect of both thyroid and estrogen hormones resulted in an additive stimulation of h-SBP secretion. 3,4,5-trimethoxybenzoic acid 74-77 selenium binding protein 1 Homo sapiens 29-32 2826889-5 1987 The hormonal regulation of h-SBP secretion by a human hepatoma cell line, H5A, showed that tri-iodothyronine was more potent than estradiol or tamoxifen, which acted as estrogen agonist, in increasing secreted h-SBP and the combined effect of both thyroid and estrogen hormones resulted in an additive stimulation of h-SBP secretion. 3,4,5-trimethoxybenzoic acid 74-77 selenium binding protein 1 Homo sapiens 27-32 2826889-5 1987 The hormonal regulation of h-SBP secretion by a human hepatoma cell line, H5A, showed that tri-iodothyronine was more potent than estradiol or tamoxifen, which acted as estrogen agonist, in increasing secreted h-SBP and the combined effect of both thyroid and estrogen hormones resulted in an additive stimulation of h-SBP secretion. Triiodothyronine 91-108 selenium binding protein 1 Homo sapiens 29-32 2826889-5 1987 The hormonal regulation of h-SBP secretion by a human hepatoma cell line, H5A, showed that tri-iodothyronine was more potent than estradiol or tamoxifen, which acted as estrogen agonist, in increasing secreted h-SBP and the combined effect of both thyroid and estrogen hormones resulted in an additive stimulation of h-SBP secretion. Triiodothyronine 91-108 selenium binding protein 1 Homo sapiens 27-32 2826889-5 1987 The hormonal regulation of h-SBP secretion by a human hepatoma cell line, H5A, showed that tri-iodothyronine was more potent than estradiol or tamoxifen, which acted as estrogen agonist, in increasing secreted h-SBP and the combined effect of both thyroid and estrogen hormones resulted in an additive stimulation of h-SBP secretion. Triiodothyronine 91-108 selenium binding protein 1 Homo sapiens 212-215 2826889-5 1987 The hormonal regulation of h-SBP secretion by a human hepatoma cell line, H5A, showed that tri-iodothyronine was more potent than estradiol or tamoxifen, which acted as estrogen agonist, in increasing secreted h-SBP and the combined effect of both thyroid and estrogen hormones resulted in an additive stimulation of h-SBP secretion. Estradiol 130-139 selenium binding protein 1 Homo sapiens 29-32 2826889-5 1987 The hormonal regulation of h-SBP secretion by a human hepatoma cell line, H5A, showed that tri-iodothyronine was more potent than estradiol or tamoxifen, which acted as estrogen agonist, in increasing secreted h-SBP and the combined effect of both thyroid and estrogen hormones resulted in an additive stimulation of h-SBP secretion. Estradiol 130-139 selenium binding protein 1 Homo sapiens 27-32 2826889-5 1987 The hormonal regulation of h-SBP secretion by a human hepatoma cell line, H5A, showed that tri-iodothyronine was more potent than estradiol or tamoxifen, which acted as estrogen agonist, in increasing secreted h-SBP and the combined effect of both thyroid and estrogen hormones resulted in an additive stimulation of h-SBP secretion. Tamoxifen 143-152 selenium binding protein 1 Homo sapiens 29-32 2826889-5 1987 The hormonal regulation of h-SBP secretion by a human hepatoma cell line, H5A, showed that tri-iodothyronine was more potent than estradiol or tamoxifen, which acted as estrogen agonist, in increasing secreted h-SBP and the combined effect of both thyroid and estrogen hormones resulted in an additive stimulation of h-SBP secretion. Tamoxifen 143-152 selenium binding protein 1 Homo sapiens 27-32 2826889-5 1987 The hormonal regulation of h-SBP secretion by a human hepatoma cell line, H5A, showed that tri-iodothyronine was more potent than estradiol or tamoxifen, which acted as estrogen agonist, in increasing secreted h-SBP and the combined effect of both thyroid and estrogen hormones resulted in an additive stimulation of h-SBP secretion. Tamoxifen 143-152 selenium binding protein 1 Homo sapiens 212-215 2826889-6 1987 As shown by Northern blot analysis, oligonucleotides synthesized from the known sequence of h-SBP hybridized with a RNA of approximately 2 kb which was more represented in H5A cells than in normal human liver, and was increased 2-3 times after hormonal stimulation of the cells. Oligonucleotides 36-52 selenium binding protein 1 Homo sapiens 94-97 3542030-2 1986 The SBP subunit consists of a 373-residue polypeptide chain containing two disulfide bonds and three oligosaccharide chains. Disulfides 75-84 selenium binding protein 1 Homo sapiens 4-7 3542030-2 1986 The SBP subunit consists of a 373-residue polypeptide chain containing two disulfide bonds and three oligosaccharide chains. Oligosaccharides 101-116 selenium binding protein 1 Homo sapiens 4-7 3080255-12 1986 Cells treated with 4 microM BPDE and allowed 12 h of incubation to perform excision repair showed removal of 60% of the initial number of ESS from HSBP DNA and 40% of the ESS from XP-A DNA. 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 28-32 selenium binding protein 1 Homo sapiens 147-151 3757145-2 1986 Cadmium (Cd2+), nickel (Ni2+) and chromate (Cr2O7) reduced the cloning efficiency of HSBP cells more than that of CHO cells whereas the reverse was true after treatment with mercury (Hg2+), manganese (Mn2+) and cobalt (Co2+). Cadmium 0-7 selenium binding protein 1 Homo sapiens 85-89 3757145-2 1986 Cadmium (Cd2+), nickel (Ni2+) and chromate (Cr2O7) reduced the cloning efficiency of HSBP cells more than that of CHO cells whereas the reverse was true after treatment with mercury (Hg2+), manganese (Mn2+) and cobalt (Co2+). Nickel 16-22 selenium binding protein 1 Homo sapiens 85-89 3757145-2 1986 Cadmium (Cd2+), nickel (Ni2+) and chromate (Cr2O7) reduced the cloning efficiency of HSBP cells more than that of CHO cells whereas the reverse was true after treatment with mercury (Hg2+), manganese (Mn2+) and cobalt (Co2+). Nickel(2+) 24-28 selenium binding protein 1 Homo sapiens 85-89 3757145-2 1986 Cadmium (Cd2+), nickel (Ni2+) and chromate (Cr2O7) reduced the cloning efficiency of HSBP cells more than that of CHO cells whereas the reverse was true after treatment with mercury (Hg2+), manganese (Mn2+) and cobalt (Co2+). Chromates 34-42 selenium binding protein 1 Homo sapiens 85-89 3757145-2 1986 Cadmium (Cd2+), nickel (Ni2+) and chromate (Cr2O7) reduced the cloning efficiency of HSBP cells more than that of CHO cells whereas the reverse was true after treatment with mercury (Hg2+), manganese (Mn2+) and cobalt (Co2+). Mercury 174-181 selenium binding protein 1 Homo sapiens 85-89 3757145-2 1986 Cadmium (Cd2+), nickel (Ni2+) and chromate (Cr2O7) reduced the cloning efficiency of HSBP cells more than that of CHO cells whereas the reverse was true after treatment with mercury (Hg2+), manganese (Mn2+) and cobalt (Co2+). Manganese 190-199 selenium binding protein 1 Homo sapiens 85-89 3757145-2 1986 Cadmium (Cd2+), nickel (Ni2+) and chromate (Cr2O7) reduced the cloning efficiency of HSBP cells more than that of CHO cells whereas the reverse was true after treatment with mercury (Hg2+), manganese (Mn2+) and cobalt (Co2+). Manganese(2+) 201-205 selenium binding protein 1 Homo sapiens 85-89 3757145-2 1986 Cadmium (Cd2+), nickel (Ni2+) and chromate (Cr2O7) reduced the cloning efficiency of HSBP cells more than that of CHO cells whereas the reverse was true after treatment with mercury (Hg2+), manganese (Mn2+) and cobalt (Co2+). Cobalt 211-217 selenium binding protein 1 Homo sapiens 85-89 3757145-2 1986 Cadmium (Cd2+), nickel (Ni2+) and chromate (Cr2O7) reduced the cloning efficiency of HSBP cells more than that of CHO cells whereas the reverse was true after treatment with mercury (Hg2+), manganese (Mn2+) and cobalt (Co2+). Cobalt(2+) 219-223 selenium binding protein 1 Homo sapiens 85-89 3757145-7 1986 DNA damage was also induced in HSBP cells following treatment with selenium but only in the presence of reduced glutathione. Selenium 67-75 selenium binding protein 1 Homo sapiens 31-35 3757145-7 1986 DNA damage was also induced in HSBP cells following treatment with selenium but only in the presence of reduced glutathione. Glutathione 112-123 selenium binding protein 1 Homo sapiens 31-35 3949754-1 1986 The effect of unsaturated and saturated nonesterified fatty acids (NEFAs) on the electrophoretic, immunological, and steroid-binding properties of human sex hormone-binding protein (SBP) were investigated. Fatty Acids, Nonesterified 67-72 selenium binding protein 1 Homo sapiens 153-180 3949754-1 1986 The effect of unsaturated and saturated nonesterified fatty acids (NEFAs) on the electrophoretic, immunological, and steroid-binding properties of human sex hormone-binding protein (SBP) were investigated. Fatty Acids, Nonesterified 67-72 selenium binding protein 1 Homo sapiens 182-185 3949754-1 1986 The effect of unsaturated and saturated nonesterified fatty acids (NEFAs) on the electrophoretic, immunological, and steroid-binding properties of human sex hormone-binding protein (SBP) were investigated. Steroids 117-124 selenium binding protein 1 Homo sapiens 182-185 3949754-3 1986 All three methods showed that NEFAs influence the binding of sex steroids to SBP both in whole serum and with the purified protein. Steroids 65-73 selenium binding protein 1 Homo sapiens 77-80 3949754-4 1986 Saturated NEFAs caused a 1.5-2-fold increase in binding of dehydrotestosterone, testosterone, and estradiol to SBP, while unsaturated NEFAs, such as oleic (18:1) and docosahexaenoic (22:6) acids inhibited the binding of these steroids to SBP. Fatty Acids, Nonesterified 10-15 selenium binding protein 1 Homo sapiens 111-114 3949754-4 1986 Saturated NEFAs caused a 1.5-2-fold increase in binding of dehydrotestosterone, testosterone, and estradiol to SBP, while unsaturated NEFAs, such as oleic (18:1) and docosahexaenoic (22:6) acids inhibited the binding of these steroids to SBP. Fatty Acids, Nonesterified 10-15 selenium binding protein 1 Homo sapiens 238-241 3949754-4 1986 Saturated NEFAs caused a 1.5-2-fold increase in binding of dehydrotestosterone, testosterone, and estradiol to SBP, while unsaturated NEFAs, such as oleic (18:1) and docosahexaenoic (22:6) acids inhibited the binding of these steroids to SBP. boldenone 59-78 selenium binding protein 1 Homo sapiens 111-114 3949754-4 1986 Saturated NEFAs caused a 1.5-2-fold increase in binding of dehydrotestosterone, testosterone, and estradiol to SBP, while unsaturated NEFAs, such as oleic (18:1) and docosahexaenoic (22:6) acids inhibited the binding of these steroids to SBP. boldenone 59-78 selenium binding protein 1 Homo sapiens 238-241 3949754-4 1986 Saturated NEFAs caused a 1.5-2-fold increase in binding of dehydrotestosterone, testosterone, and estradiol to SBP, while unsaturated NEFAs, such as oleic (18:1) and docosahexaenoic (22:6) acids inhibited the binding of these steroids to SBP. Testosterone 66-78 selenium binding protein 1 Homo sapiens 111-114 3949754-4 1986 Saturated NEFAs caused a 1.5-2-fold increase in binding of dehydrotestosterone, testosterone, and estradiol to SBP, while unsaturated NEFAs, such as oleic (18:1) and docosahexaenoic (22:6) acids inhibited the binding of these steroids to SBP. Estradiol 98-107 selenium binding protein 1 Homo sapiens 111-114 2879464-2 1986 The efficacy of tertatolol was confirmed by a reduction in heart rate (HR), and in systolic (SBP) and diastolic (DBP) blood pressure, in the supine position and after 1 min in the upright position. tertatolol 16-26 selenium binding protein 1 Homo sapiens 93-96 3540223-8 1986 Mean SBP and DBP varied similarly during waking and sleeping periods with IR and SR verapamil: With IR verapamil, SBP was 139 +/- 18 and 124 +/- 20 mmHg and DBP was 92 +/- 11 and 84 +/- 13 mmHg during waking and sleeping hours, respectively; with SR verapamil, SBP was 138 +/- 21 and 122 +/- 22 mmHg and DBP 92 +/- 10 and 80 +/- 10 mmHg during waking and sleeping hours, respectively. Verapamil 103-112 selenium binding protein 1 Homo sapiens 114-117 3540223-8 1986 Mean SBP and DBP varied similarly during waking and sleeping periods with IR and SR verapamil: With IR verapamil, SBP was 139 +/- 18 and 124 +/- 20 mmHg and DBP was 92 +/- 11 and 84 +/- 13 mmHg during waking and sleeping hours, respectively; with SR verapamil, SBP was 138 +/- 21 and 122 +/- 22 mmHg and DBP 92 +/- 10 and 80 +/- 10 mmHg during waking and sleeping hours, respectively. Verapamil 103-112 selenium binding protein 1 Homo sapiens 114-117 3540223-8 1986 Mean SBP and DBP varied similarly during waking and sleeping periods with IR and SR verapamil: With IR verapamil, SBP was 139 +/- 18 and 124 +/- 20 mmHg and DBP was 92 +/- 11 and 84 +/- 13 mmHg during waking and sleeping hours, respectively; with SR verapamil, SBP was 138 +/- 21 and 122 +/- 22 mmHg and DBP 92 +/- 10 and 80 +/- 10 mmHg during waking and sleeping hours, respectively. Verapamil 103-112 selenium binding protein 1 Homo sapiens 114-117 3540223-8 1986 Mean SBP and DBP varied similarly during waking and sleeping periods with IR and SR verapamil: With IR verapamil, SBP was 139 +/- 18 and 124 +/- 20 mmHg and DBP was 92 +/- 11 and 84 +/- 13 mmHg during waking and sleeping hours, respectively; with SR verapamil, SBP was 138 +/- 21 and 122 +/- 22 mmHg and DBP 92 +/- 10 and 80 +/- 10 mmHg during waking and sleeping hours, respectively. Verapamil 103-112 selenium binding protein 1 Homo sapiens 114-117 3734452-5 1986 With control for age, body mass index and pulse in multivariate analyses, only the relationship of Na:K and Na:creatinine to SBP and DBP remained significant for men; a similar, though less strong and consistent, trend was found for women, and K was inversely related to SBP for women. Creatinine 111-121 selenium binding protein 1 Homo sapiens 125-128 3718973-1 1986 The interaction of the estrogen d-3-hydroxy-1,3,5(10),6,8-estrapentaen-17-one (equilenin) with the human and rabbit sex steroid binding proteins (hSBP and rSBP, respectively) has been investigated by using fluorescence and absorption spectroscopy. Equilenin 32-77 selenium binding protein 1 Homo sapiens 146-150 3718973-1 1986 The interaction of the estrogen d-3-hydroxy-1,3,5(10),6,8-estrapentaen-17-one (equilenin) with the human and rabbit sex steroid binding proteins (hSBP and rSBP, respectively) has been investigated by using fluorescence and absorption spectroscopy. Equilenin 79-88 selenium binding protein 1 Homo sapiens 146-150 3718973-1 1986 The interaction of the estrogen d-3-hydroxy-1,3,5(10),6,8-estrapentaen-17-one (equilenin) with the human and rabbit sex steroid binding proteins (hSBP and rSBP, respectively) has been investigated by using fluorescence and absorption spectroscopy. Steroids 120-127 selenium binding protein 1 Homo sapiens 146-150 3718973-7 1986 The fluorescence excitation spectra of SBP-equilenin complexes are similar to the absorption spectra of equilenin in low-dielectric solvents. Equilenin 43-52 selenium binding protein 1 Homo sapiens 39-42 3718973-7 1986 The fluorescence excitation spectra of SBP-equilenin complexes are similar to the absorption spectra of equilenin in low-dielectric solvents. Equilenin 104-113 selenium binding protein 1 Homo sapiens 39-42 3718973-8 1986 The fluorescence emission of the SBP-equilenin complexes, however, exhibits wavelength shifts (red shifts) opposite to those of the steroid in low-dielectric solvents or complexed with beta-cyclodextrin (blue shifts) but similar to the red shift produced by addition of the proton acceptor triethylamine to equilenin in cyclohexane. Equilenin 37-46 selenium binding protein 1 Homo sapiens 33-36 3718973-8 1986 The fluorescence emission of the SBP-equilenin complexes, however, exhibits wavelength shifts (red shifts) opposite to those of the steroid in low-dielectric solvents or complexed with beta-cyclodextrin (blue shifts) but similar to the red shift produced by addition of the proton acceptor triethylamine to equilenin in cyclohexane. Steroids 132-139 selenium binding protein 1 Homo sapiens 33-36 3718973-8 1986 The fluorescence emission of the SBP-equilenin complexes, however, exhibits wavelength shifts (red shifts) opposite to those of the steroid in low-dielectric solvents or complexed with beta-cyclodextrin (blue shifts) but similar to the red shift produced by addition of the proton acceptor triethylamine to equilenin in cyclohexane. betadex 185-202 selenium binding protein 1 Homo sapiens 33-36 3718973-8 1986 The fluorescence emission of the SBP-equilenin complexes, however, exhibits wavelength shifts (red shifts) opposite to those of the steroid in low-dielectric solvents or complexed with beta-cyclodextrin (blue shifts) but similar to the red shift produced by addition of the proton acceptor triethylamine to equilenin in cyclohexane. triethylamine 290-303 selenium binding protein 1 Homo sapiens 33-36 3718973-8 1986 The fluorescence emission of the SBP-equilenin complexes, however, exhibits wavelength shifts (red shifts) opposite to those of the steroid in low-dielectric solvents or complexed with beta-cyclodextrin (blue shifts) but similar to the red shift produced by addition of the proton acceptor triethylamine to equilenin in cyclohexane. Equilenin 307-316 selenium binding protein 1 Homo sapiens 33-36 3718973-8 1986 The fluorescence emission of the SBP-equilenin complexes, however, exhibits wavelength shifts (red shifts) opposite to those of the steroid in low-dielectric solvents or complexed with beta-cyclodextrin (blue shifts) but similar to the red shift produced by addition of the proton acceptor triethylamine to equilenin in cyclohexane. Cyclohexane 320-331 selenium binding protein 1 Homo sapiens 33-36 3718973-9 1986 These data indicate that the steroid-binding site of hSBP and rSBP is a nonpolar cavity containing a proton acceptor that participates in a specific interaction, possibly a hydrogen bond, with the 3"-hydroxyl group of the bound steroid. Steroids 29-36 selenium binding protein 1 Homo sapiens 53-57 3718973-9 1986 These data indicate that the steroid-binding site of hSBP and rSBP is a nonpolar cavity containing a proton acceptor that participates in a specific interaction, possibly a hydrogen bond, with the 3"-hydroxyl group of the bound steroid. Hydrogen 173-181 selenium binding protein 1 Homo sapiens 53-57 3718973-9 1986 These data indicate that the steroid-binding site of hSBP and rSBP is a nonpolar cavity containing a proton acceptor that participates in a specific interaction, possibly a hydrogen bond, with the 3"-hydroxyl group of the bound steroid. Steroids 228-235 selenium binding protein 1 Homo sapiens 53-57 2939208-10 1986 Ambulatory monitoring showed a significant 24-h reduction of SBP after administration of propranolol (P less than 0.0025) and ketanserin (A:P less than 0.0025, B: P less than 0.005). Propranolol 89-100 selenium binding protein 1 Homo sapiens 61-64 3949754-4 1986 Saturated NEFAs caused a 1.5-2-fold increase in binding of dehydrotestosterone, testosterone, and estradiol to SBP, while unsaturated NEFAs, such as oleic (18:1) and docosahexaenoic (22:6) acids inhibited the binding of these steroids to SBP. docosahexaenoic 166-181 selenium binding protein 1 Homo sapiens 111-114 3949754-4 1986 Saturated NEFAs caused a 1.5-2-fold increase in binding of dehydrotestosterone, testosterone, and estradiol to SBP, while unsaturated NEFAs, such as oleic (18:1) and docosahexaenoic (22:6) acids inhibited the binding of these steroids to SBP. Steroids 226-234 selenium binding protein 1 Homo sapiens 111-114 3949754-6 1986 In addition to these binding changes, polyacrylamide gel electrophoresis and immunoelectrophoretic studies revealed a shift in SBP from the slow-moving active native form to a fast-moving inactive one. polyacrylamide 38-52 selenium binding protein 1 Homo sapiens 127-130 3949754-7 1986 There was also a reduction in the apparent SBP concentration by Laurell immunoelectrophoresis in the presence of unsaturated NEFA (5.5 nmol of NEFA/pmol of protein). unsaturated nefa 113-129 selenium binding protein 1 Homo sapiens 43-46 3949754-7 1986 There was also a reduction in the apparent SBP concentration by Laurell immunoelectrophoresis in the presence of unsaturated NEFA (5.5 nmol of NEFA/pmol of protein). Fatty Acids, Nonesterified 125-129 selenium binding protein 1 Homo sapiens 43-46 3949754-8 1986 These studies indicate that unsaturated NEFAs induce conformational changes in human SBP which are reflected in its electrophoretic, immunological, and steroid-binding properties. unsaturated nefas 28-45 selenium binding protein 1 Homo sapiens 85-88 3949754-8 1986 These studies indicate that unsaturated NEFAs induce conformational changes in human SBP which are reflected in its electrophoretic, immunological, and steroid-binding properties. Steroids 152-159 selenium binding protein 1 Homo sapiens 85-88 3949754-9 1986 They suggest that the fatty acid content of the SBP environment may result in lower steroid hormone binding and thus increased free hormone levels. Fatty Acids 22-32 selenium binding protein 1 Homo sapiens 48-51 3949754-9 1986 They suggest that the fatty acid content of the SBP environment may result in lower steroid hormone binding and thus increased free hormone levels. Steroids 84-99 selenium binding protein 1 Homo sapiens 48-51 3080255-12 1986 Cells treated with 4 microM BPDE and allowed 12 h of incubation to perform excision repair showed removal of 60% of the initial number of ESS from HSBP DNA and 40% of the ESS from XP-A DNA. ESS 138-141 selenium binding protein 1 Homo sapiens 147-151 3080255-13 1986 Beyond 12 h XP12BE cells lost no additional ESS while HSBP cells continued to lose ESS, although at a slower rate, until at 48 h only 22% of the initial ESS remained. ESS 83-86 selenium binding protein 1 Homo sapiens 54-58 3080255-13 1986 Beyond 12 h XP12BE cells lost no additional ESS while HSBP cells continued to lose ESS, although at a slower rate, until at 48 h only 22% of the initial ESS remained. ESS 83-86 selenium binding protein 1 Homo sapiens 54-58 2439808-6 1986 Systolic (SBP) and diastolic (DBP) blood pressure, and heart rate (HR) were significantly (p less than 0.01) reduced after 2 weeks of bisoprolol therapy, compared with placebo. Bisoprolol 134-144 selenium binding protein 1 Homo sapiens 10-13 3009989-4 1986 In a chemically defined medium, SBP-like protein secretion was stimulated approx 2-fold by estradiol (1 microM) whereas a smaller concentration of estrogen (100 nM) has only a slight effect. Estradiol 91-100 selenium binding protein 1 Homo sapiens 32-35 3009989-5 1986 A combined incubation with estradiol (100 nM) and triiodothyronine (10 nM) increased SBP-like protein secretion more than estradiol (1 microM) alone. Estradiol 27-36 selenium binding protein 1 Homo sapiens 85-88 3009989-5 1986 A combined incubation with estradiol (100 nM) and triiodothyronine (10 nM) increased SBP-like protein secretion more than estradiol (1 microM) alone. Triiodothyronine 50-66 selenium binding protein 1 Homo sapiens 85-88 2856742-5 1985 The dopamine receptor agonist fenoldopam decreased by preload 24% (P < 0.05) and increased all of the three parameters of myocardial contractility (SBP:SV 66%; EF 17%, Vcf 19%; P < 0.01). Fenoldopam 30-40 selenium binding protein 1 Homo sapiens 151-154 3702428-4 1986 The experimental approach was to reduce and [14C]alkylate cystine residues in human SBP, digest the product with trypsin or cyanogen bromide and determine the number of unique amino acid sequences around each [14C]carboxymethylcysteine residue. Carbon-14 45-48 selenium binding protein 1 Homo sapiens 84-87 4074807-0 1985 Control of plasma sex steroid-binding protein (SBP) in the little brown bat: effects of thyroidectomy and treatment with L- and D-thyroxine on the induction of SBP in adult males. l- and d-thyroxine 121-139 selenium binding protein 1 Homo sapiens 160-163 4074807-6 1985 The postarousal rise in SBP, which was blocked by TRX, was completely restored by implantation of either L- or D-thyroxine pellets. l- or d-thyroxine 105-122 selenium binding protein 1 Homo sapiens 24-27 2418302-4 1985 At the end of step 1 (85 +/- 6 days with nicardipine vs. 58 +/- 6 days with placebo, p less than 0.01), nicardipine induced larger drops in supine systolic and diastolic blood pressure (SBP and DBP) than the placebo (21 +/- 2.5 vs 1.4 +/- 3 mm Hg, p less than 0.001, and 13 +/- 2 vs. 3.5 +/- 1.5 mm Hg, p less than 0.001, respectively). Nicardipine 104-115 selenium binding protein 1 Homo sapiens 186-189 3937509-4 1985 In the indapamide group, the SBP fell from 164 +/- 13 mmHg to 152 +/- 15 mmHg (p less than 0.01) and the DBP from 100 +/- 4 mmHg to 87 +/- 6 mmHg (p less than 0.01). Indapamide 7-17 selenium binding protein 1 Homo sapiens 29-32 3907792-4 1985 Increases in systolic (SBP) and diastolic (DBP) blood pressure were significantly smaller in the group receiving fentanyl at one minute post intubation. Fentanyl 113-121 selenium binding protein 1 Homo sapiens 23-26 3907792-5 1985 SBP rose by 56 mmHg in the control group, compared to 15 mmHg in the fentanyl group; DBP increased 42 mmHg compared to 20 mmHg, respectively. Fentanyl 69-77 selenium binding protein 1 Homo sapiens 0-3 2418302-5 1985 In the nicardipine group (n = 57), 53% of patients had controlled blood pressure (SBP less than 160 mm Hg and DBP less than 95 mm Hg) versus 17% in the placebo group (n = 47), p less than 0.001. Nicardipine 7-18 selenium binding protein 1 Homo sapiens 82-85 2418302-8 1985 When blood pressure was not brought under control and pindolol was prescribed as the second-step treatment, the nicardipine group (n = 52) displayed larger drops in SBP and DBP than the placebo group (n = 40) (27 +/- 5 vs. 15 +/- 3 mm Hg, p less than 0.01, and 18 +/- 1 vs. 9 +/- 2 mm Hg, p less than 0.001, respectively). Nicardipine 112-123 selenium binding protein 1 Homo sapiens 165-168 3902677-2 1985 Intravenous infusion of 1.5 mg DHT significantly reduced both systolic (SBP) and diastolic (DBP) blood pressure from 227 +/- 2/128 +/- 2 mmHg to 160 +/- 4/94 +/- 2 mmHg by 1 hour after the onset of infusion (p less than 0.01). Ergoloid Mesylates 31-34 selenium binding protein 1 Homo sapiens 72-75 3934028-1 1985 Reproductively active female Bufo arenarum possess a serum protein (SBP) that binds testosterone, dihydrotestosterone, and estradiol with high affinity and capacity. Testosterone 84-96 selenium binding protein 1 Homo sapiens 68-71 3934028-1 1985 Reproductively active female Bufo arenarum possess a serum protein (SBP) that binds testosterone, dihydrotestosterone, and estradiol with high affinity and capacity. Dihydrotestosterone 98-117 selenium binding protein 1 Homo sapiens 68-71 3934028-1 1985 Reproductively active female Bufo arenarum possess a serum protein (SBP) that binds testosterone, dihydrotestosterone, and estradiol with high affinity and capacity. Estradiol 123-132 selenium binding protein 1 Homo sapiens 68-71 3934028-3 1985 The specificity of B. arenarum SBP is comparable to human SBP with the exception that it has a high affinity for the synthetic androgen methyltrienolone (R1881). Metribolone 136-152 selenium binding protein 1 Homo sapiens 31-34 3908501-4 1985 After six weeks of treatment, the two groups that received carteolol had significant reductions in systolic (SBP) and diastolic (DBP) blood pressure from baseline in both the supine and standing positions. Carteolol 59-68 selenium binding protein 1 Homo sapiens 109-112 4041491-1 1985 Plasma membranes of decidual tissue cells specifically bind the sex steroid-binding globulin (SBP) complexes with estrogen (estradiol, estriol, estrone) and with the pharmacological agent danazol but do not interact with the SBP-testosterone or SBP-dihydrotestosterone complexes. Steroids 68-75 selenium binding protein 1 Homo sapiens 94-97 2416602-2 1985 The effect of sodium molybdate on the specific binding protein (SBP) of synthetic progestin 17 alpha-methyl-[3H]-promegestone (R5020) in the cytosol of the human prostate was studied. sodium molybdate(VI) 14-30 selenium binding protein 1 Homo sapiens 64-67 2416602-2 1985 The effect of sodium molybdate on the specific binding protein (SBP) of synthetic progestin 17 alpha-methyl-[3H]-promegestone (R5020) in the cytosol of the human prostate was studied. alpha-methyl-[3h 95-111 selenium binding protein 1 Homo sapiens 38-62 2416602-2 1985 The effect of sodium molybdate on the specific binding protein (SBP) of synthetic progestin 17 alpha-methyl-[3H]-promegestone (R5020) in the cytosol of the human prostate was studied. alpha-methyl-[3h 95-111 selenium binding protein 1 Homo sapiens 64-67 2416602-3 1985 In a sucrose density gradient analysis, two R5020 SBP components at 4S and 7-8S were observed. Sucrose 5-12 selenium binding protein 1 Homo sapiens 50-53 2416602-5 1985 Therefore, the molybdate enhancement degree on total SBP amount (4S plus 7-8S) was decided by the relationship between the decreasing rate at 4S and the increasing one at 7-8S. molybdate 15-24 selenium binding protein 1 Homo sapiens 53-56 2416602-7 1985 Moreover, it was estimated that the molybdate effect was not related to phosphatase inhibition since R5020 SBP in SDG was not enhanced by the addition of sodium fluoride which was a phosphatase inhibitor. molybdate 36-45 selenium binding protein 1 Homo sapiens 107-110 2416602-7 1985 Moreover, it was estimated that the molybdate effect was not related to phosphatase inhibition since R5020 SBP in SDG was not enhanced by the addition of sodium fluoride which was a phosphatase inhibitor. secoisolariciresinol diglucoside 114-117 selenium binding protein 1 Homo sapiens 107-110 4041491-2 1985 The selectivity of interaction of the SBP-steroid complexes with decidual tissue cellular membranes provide evidence for the active role of SBP in the realization of steroid effects on the target tissue. Steroids 42-49 selenium binding protein 1 Homo sapiens 38-41 4041491-1 1985 Plasma membranes of decidual tissue cells specifically bind the sex steroid-binding globulin (SBP) complexes with estrogen (estradiol, estriol, estrone) and with the pharmacological agent danazol but do not interact with the SBP-testosterone or SBP-dihydrotestosterone complexes. Steroids 68-75 selenium binding protein 1 Homo sapiens 225-228 4041491-2 1985 The selectivity of interaction of the SBP-steroid complexes with decidual tissue cellular membranes provide evidence for the active role of SBP in the realization of steroid effects on the target tissue. Steroids 42-49 selenium binding protein 1 Homo sapiens 140-143 4041491-1 1985 Plasma membranes of decidual tissue cells specifically bind the sex steroid-binding globulin (SBP) complexes with estrogen (estradiol, estriol, estrone) and with the pharmacological agent danazol but do not interact with the SBP-testosterone or SBP-dihydrotestosterone complexes. Steroids 68-75 selenium binding protein 1 Homo sapiens 225-228 4041491-2 1985 The selectivity of interaction of the SBP-steroid complexes with decidual tissue cellular membranes provide evidence for the active role of SBP in the realization of steroid effects on the target tissue. Steroids 166-173 selenium binding protein 1 Homo sapiens 38-41 4041491-2 1985 The selectivity of interaction of the SBP-steroid complexes with decidual tissue cellular membranes provide evidence for the active role of SBP in the realization of steroid effects on the target tissue. Steroids 166-173 selenium binding protein 1 Homo sapiens 140-143 4041491-1 1985 Plasma membranes of decidual tissue cells specifically bind the sex steroid-binding globulin (SBP) complexes with estrogen (estradiol, estriol, estrone) and with the pharmacological agent danazol but do not interact with the SBP-testosterone or SBP-dihydrotestosterone complexes. Estradiol 124-133 selenium binding protein 1 Homo sapiens 94-97 4041491-1 1985 Plasma membranes of decidual tissue cells specifically bind the sex steroid-binding globulin (SBP) complexes with estrogen (estradiol, estriol, estrone) and with the pharmacological agent danazol but do not interact with the SBP-testosterone or SBP-dihydrotestosterone complexes. Estriol 135-142 selenium binding protein 1 Homo sapiens 94-97 4041491-1 1985 Plasma membranes of decidual tissue cells specifically bind the sex steroid-binding globulin (SBP) complexes with estrogen (estradiol, estriol, estrone) and with the pharmacological agent danazol but do not interact with the SBP-testosterone or SBP-dihydrotestosterone complexes. Estrone 144-151 selenium binding protein 1 Homo sapiens 94-97 4041491-1 1985 Plasma membranes of decidual tissue cells specifically bind the sex steroid-binding globulin (SBP) complexes with estrogen (estradiol, estriol, estrone) and with the pharmacological agent danazol but do not interact with the SBP-testosterone or SBP-dihydrotestosterone complexes. Danazol 188-195 selenium binding protein 1 Homo sapiens 94-97 3896280-9 1985 Reinstitution of nicardipine at the previous dose resulted in a reduction of SBP and DBP to levels not significantly different from those at the end of the dose-titration stage. Nicardipine 17-28 selenium binding protein 1 Homo sapiens 77-80 3973613-2 1985 5-Hydroxytryptamine (5-HT, serotonin) is physiologically stored as a complex with SBP in vivo. Serotonin 0-19 selenium binding protein 1 Homo sapiens 82-85 3973613-2 1985 5-Hydroxytryptamine (5-HT, serotonin) is physiologically stored as a complex with SBP in vivo. Serotonin 27-36 selenium binding protein 1 Homo sapiens 82-85 4034510-1 1985 Recent epidemiologic studies report a significant association between alcohol consumption and elevations in both systolic (SBP) and diastolic (DBP) blood pressures. Alcohols 70-77 selenium binding protein 1 Homo sapiens 123-126 3159517-5 1985 Patients on Oxprenolol consistently had lower SBP at a particular level of physical activity and at lower levels of arousal than patients on Nitrendipine. Oxprenolol 12-22 selenium binding protein 1 Homo sapiens 46-49 6529523-5 1984 The hourly mean values of SBP recorded for 8/12 h (first tiapamil day) and 10/12 h (seventh tiapamil day) were significantly lower than the corresponding values after placebo. Tiapamil Hydrochloride 57-65 selenium binding protein 1 Homo sapiens 26-29 6529523-5 1984 The hourly mean values of SBP recorded for 8/12 h (first tiapamil day) and 10/12 h (seventh tiapamil day) were significantly lower than the corresponding values after placebo. Tiapamil Hydrochloride 92-100 selenium binding protein 1 Homo sapiens 26-29 6529523-3 1984 Tiapamil led to a decrease in mean daytime systolic (SBP) and diastolic (DBP) BP from 171 +/- 12/98 +/- 10 mm Hg to 159 +/- 11/90 +/- 9 mm Hg (P less than 0.001) without significant variation in HR. Tiapamil Hydrochloride 0-8 selenium binding protein 1 Homo sapiens 53-56 6152301-5 1984 Following induction of anesthesia by diazepam-vecuronium-fentanyl sequence, there was a decrease in SBP by 20.0% (P less than 0.05), in HR by 15.7% (P less than 0.001) in C.O by 13.3% (P less than 0.01) and in SVR by 13.6% (P less than 0.05) of control value. Diazepam 37-45 selenium binding protein 1 Homo sapiens 100-103 6734028-3 1984 Heart rate (HR) and systolic (SBP) and diastolic (DBP) blood pressure responses to fenoterol were small (means +/- SE; HR: +4 +/- 1.3 bpm; SBP: +6 +/- 1.3 mm Hg; DBP: -3 +/- 1.4 mm Hg). Fenoterol 83-92 selenium binding protein 1 Homo sapiens 30-33 6734028-3 1984 Heart rate (HR) and systolic (SBP) and diastolic (DBP) blood pressure responses to fenoterol were small (means +/- SE; HR: +4 +/- 1.3 bpm; SBP: +6 +/- 1.3 mm Hg; DBP: -3 +/- 1.4 mm Hg). Fenoterol 83-92 selenium binding protein 1 Homo sapiens 139-142 6152301-5 1984 Following induction of anesthesia by diazepam-vecuronium-fentanyl sequence, there was a decrease in SBP by 20.0% (P less than 0.05), in HR by 15.7% (P less than 0.001) in C.O by 13.3% (P less than 0.01) and in SVR by 13.6% (P less than 0.05) of control value. Vecuronium Bromide 46-56 selenium binding protein 1 Homo sapiens 100-103 6637977-5 1983 In men, age-specific analysis revealed a positive association between dietary alcohol and both systolic (SBP) and diastolic blood pressure (DBP). Alcohols 78-85 selenium binding protein 1 Homo sapiens 105-108 6152301-5 1984 Following induction of anesthesia by diazepam-vecuronium-fentanyl sequence, there was a decrease in SBP by 20.0% (P less than 0.05), in HR by 15.7% (P less than 0.001) in C.O by 13.3% (P less than 0.01) and in SVR by 13.6% (P less than 0.05) of control value. Fentanyl 57-65 selenium binding protein 1 Homo sapiens 100-103 6422984-4 1984 One molecule of 5 alpha-dihydrotestosterone is bound per dimer with a KD equal to 1.6 nM at 11 degrees C. Isoelectric focusing patterns reveal the presence of at least 12 different forms of dimeric SBP molecules probably resulting from the presence of different amounts or types of carbohydrate side chains. alpha-dihydrotestosterone 18-43 selenium binding protein 1 Homo sapiens 198-201 6422984-4 1984 One molecule of 5 alpha-dihydrotestosterone is bound per dimer with a KD equal to 1.6 nM at 11 degrees C. Isoelectric focusing patterns reveal the presence of at least 12 different forms of dimeric SBP molecules probably resulting from the presence of different amounts or types of carbohydrate side chains. Carbohydrates 282-294 selenium binding protein 1 Homo sapiens 198-201 6637977-8 1983 This association remained significant in a linear regression model that included age, relative weight, income, education, physical activity, cigarette use, and untimed urinary sodium/creatinine; for alcohol in ml/day in men aged 50-74, beta = 0.21, p = 0.0001, R2 = 0.32 for SBP; beta = 0.09, p = 0.0002, R2 = 0.18 for DBP. Alcohols 199-206 selenium binding protein 1 Homo sapiens 275-278 6637977-9 1983 In women, alcohol use was significantly associated with blood pressure only in those above age 49 and was more striking in those not taking estrogens; this association was also independent of the same variables listed above for men (beta = 0.43, p = 0.0001, R2 = 0.23 for SBP; beta = 0.17, p = 0.001, R2 = 0.13 for DBP). Alcohols 10-17 selenium binding protein 1 Homo sapiens 272-275 6891343-1 1982 Equilenin, a naturally fluorescent steroid, has high binding affinity for human sex steroid-binding protein (SBP). Steroids 35-42 selenium binding protein 1 Homo sapiens 109-112 6684195-7 1983 The effect is complex and depends on the concentration of SBP, albumin, and testosterone which in turn influences the distribution of testosterone between albumin and SBP. Testosterone 76-88 selenium binding protein 1 Homo sapiens 167-170 6191127-1 1983 The binding affinity of various substituted estrogens for human sex steroid binding protein (SBP) and rat alpha-fetoprotein (AFP) have been measured by hydroxylapatite adsorption (relative to estradiol = 100%). Durapatite 152-167 selenium binding protein 1 Homo sapiens 93-96 6668661-2 1983 Indapamide, a sulphonamide derivative, was prescribed for 8 weeks at low dose (2.5 mg once a day) to 14 hypertensive patients in order to investigate its effects on systolic and diastolic blood pressure (SBP, DBP), cardiac function and peripheral arterial resistance (PAR). Indapamide 0-10 selenium binding protein 1 Homo sapiens 204-207 6684195-5 1983 The existence of the large number of dimeric forms of SBP arises through the combination of many variants of the same two subunits containing different amounts and types of carbohydrate sidechains. Carbohydrates 173-185 selenium binding protein 1 Homo sapiens 54-57 6837548-1 1983 We have prospectively studied the value of ascitic fluid lactic acid levels by a rapid kit method in the diagnosis of SBP. Lactic Acid 57-68 selenium binding protein 1 Homo sapiens 118-121 6837548-10 1983 (5), which used the same method and when the lactic acid results of both studies are combined, the sensitivity of lactic acid in SBP is 100% (15/15), the specificity is 96% (79/82), the predictive value positive is 83% (15/18), and the predictive value negative is 100% (76/76). Lactic Acid 114-125 selenium binding protein 1 Homo sapiens 129-132 7136994-4 1982 The correlation between two mercury manometer readings was SBP r = 0.90, and DBP r = 0.75. Mercury 28-35 selenium binding protein 1 Homo sapiens 59-62 7124595-3 1982 Finger SBP was higher (p less than 0.01) in BHT than in NT (120 +/- 18.7 vs. 104 +/- 14.8 mm Hg, respectively); PV was lower (p less than 0.01) in BHT than in NT (9.7 +/- 4.2 vs. 15.3 +/- 6 ml/5 ml finger X 10(-3). Butylated Hydroxytoluene 44-47 selenium binding protein 1 Homo sapiens 7-10 7124595-4 1982 Pulse volume correlated inversely with SBP in BHT (r = -0.40, p less than 0.05) but was unrelated to SBP in NT. Butylated Hydroxytoluene 46-49 selenium binding protein 1 Homo sapiens 39-42 7036714-6 1981 Following isoproterenol administration, SBP increased (p less than 0.01), PTH fell (p less than 0.05) and Ca++ was only minimally increased in the Tx recipients. Isoproterenol 10-23 selenium binding protein 1 Homo sapiens 40-43 6810813-5 1982 With ACEBUTOLOL treatment, during the test described and during dynamic stress on ergometric bicycle, HR and SBP are always less elevated. Acebutolol 5-15 selenium binding protein 1 Homo sapiens 109-112 7183084-5 1982 During the Si group A exhibited a higher rise in SBP, HR, and PRi as well as higher maximal reactions in SBP and PRi. Silicon 11-13 selenium binding protein 1 Homo sapiens 49-52 7104157-6 1982 5 Compared with the placebo period, both pindolol and metoprolol significantly reduced heart rate (HR) and systolic (SBP) and diastolic (DBP) blood pressure. Pindolol 41-49 selenium binding protein 1 Homo sapiens 117-120 7104157-6 1982 5 Compared with the placebo period, both pindolol and metoprolol significantly reduced heart rate (HR) and systolic (SBP) and diastolic (DBP) blood pressure. Metoprolol 54-64 selenium binding protein 1 Homo sapiens 117-120 7197986-4 1981 Parallel measurements of dihydrotestosterone-binding capacity of SBP showed a good correlation between SBP content and biological activity. Dihydrotestosterone 25-44 selenium binding protein 1 Homo sapiens 65-68 7197986-4 1981 Parallel measurements of dihydrotestosterone-binding capacity of SBP showed a good correlation between SBP content and biological activity. Dihydrotestosterone 25-44 selenium binding protein 1 Homo sapiens 103-106 7197818-0 1981 Steroid structural requirements for high affinity binding to human sex steroid binding protein (SBP). Steroids 0-7 selenium binding protein 1 Homo sapiens 96-99 7197818-2 1981 SBP was purified partially and the ability of each of more than 150 steroids to compete with [3H]dihydrotestosterone (17 beta-hydroxy-5 alpha-androstan-3-one) for binding to SBP was assessed. Steroids 68-76 selenium binding protein 1 Homo sapiens 0-3 7197818-2 1981 SBP was purified partially and the ability of each of more than 150 steroids to compete with [3H]dihydrotestosterone (17 beta-hydroxy-5 alpha-androstan-3-one) for binding to SBP was assessed. Steroids 68-76 selenium binding protein 1 Homo sapiens 174-177 7197818-2 1981 SBP was purified partially and the ability of each of more than 150 steroids to compete with [3H]dihydrotestosterone (17 beta-hydroxy-5 alpha-androstan-3-one) for binding to SBP was assessed. Dihydrotestosterone 93-116 selenium binding protein 1 Homo sapiens 0-3 7197818-2 1981 SBP was purified partially and the ability of each of more than 150 steroids to compete with [3H]dihydrotestosterone (17 beta-hydroxy-5 alpha-androstan-3-one) for binding to SBP was assessed. Dihydrotestosterone 93-116 selenium binding protein 1 Homo sapiens 174-177 7197818-2 1981 SBP was purified partially and the ability of each of more than 150 steroids to compete with [3H]dihydrotestosterone (17 beta-hydroxy-5 alpha-androstan-3-one) for binding to SBP was assessed. Dihydrotestosterone 118-157 selenium binding protein 1 Homo sapiens 0-3 7197818-2 1981 SBP was purified partially and the ability of each of more than 150 steroids to compete with [3H]dihydrotestosterone (17 beta-hydroxy-5 alpha-androstan-3-one) for binding to SBP was assessed. Dihydrotestosterone 118-157 selenium binding protein 1 Homo sapiens 174-177 6933505-4 1980 The dog has an unusual Sbp (Kd for dihydrotestosterone, 7.1 nM; for estradiol, 125 nM), and rodents do not have a specific dihydrotestosterone-binding plasma protein. Dihydrotestosterone 35-54 selenium binding protein 1 Homo sapiens 23-26 6766666-1 1980 Several species of primates have sex differences in sex steroid-binding protein (SBP), female adults having higher serum binding capacities (micrograms of dihydrotestosterone bound per deciliter) than male adults, e.g., male humans, 1.28 +/- 0.4; human females, 2.86 +4- 0.9; Macaca nemestrina male animals, 5.62 +/- 1.24; Macaca nemestrina female animals, 11.07 +/- 1.85 (means +/- standard deviations). Dihydrotestosterone 155-174 selenium binding protein 1 Homo sapiens 81-84 6933505-1 1980 Sex steoid binding plasma protein (Sbp) in man and in monkeys binds the androgens dihydrotestosterone and testosterone and the estrogen estradiol with high affinity (Kd approximately 0.5, 1, and 2 nM, respectively). Dihydrotestosterone 82-101 selenium binding protein 1 Homo sapiens 4-33 6933505-1 1980 Sex steoid binding plasma protein (Sbp) in man and in monkeys binds the androgens dihydrotestosterone and testosterone and the estrogen estradiol with high affinity (Kd approximately 0.5, 1, and 2 nM, respectively). Dihydrotestosterone 82-101 selenium binding protein 1 Homo sapiens 35-38 6933505-1 1980 Sex steoid binding plasma protein (Sbp) in man and in monkeys binds the androgens dihydrotestosterone and testosterone and the estrogen estradiol with high affinity (Kd approximately 0.5, 1, and 2 nM, respectively). Testosterone 89-101 selenium binding protein 1 Homo sapiens 4-33 6933505-1 1980 Sex steoid binding plasma protein (Sbp) in man and in monkeys binds the androgens dihydrotestosterone and testosterone and the estrogen estradiol with high affinity (Kd approximately 0.5, 1, and 2 nM, respectively). Testosterone 89-101 selenium binding protein 1 Homo sapiens 35-38 6933505-1 1980 Sex steoid binding plasma protein (Sbp) in man and in monkeys binds the androgens dihydrotestosterone and testosterone and the estrogen estradiol with high affinity (Kd approximately 0.5, 1, and 2 nM, respectively). Estradiol 136-145 selenium binding protein 1 Homo sapiens 4-33 6933505-1 1980 Sex steoid binding plasma protein (Sbp) in man and in monkeys binds the androgens dihydrotestosterone and testosterone and the estrogen estradiol with high affinity (Kd approximately 0.5, 1, and 2 nM, respectively). Estradiol 136-145 selenium binding protein 1 Homo sapiens 35-38 6766666-2 1980 SBP correlates inversely with metabolic clearance rates of testosterone (T). Testosterone 59-71 selenium binding protein 1 Homo sapiens 0-3 6766666-4 1980 Estradiol-17 beta (E2) pellets producing physiologic levels of E2 in female monkeys obliterated the sex difference by increasing SBP in male animals. estradiol-17 beta (e2) 0-22 selenium binding protein 1 Homo sapiens 129-132 6766666-7 1980 These data suggest that the sex steroid milieu influences the binding capacity of SBP for potent androgens in adulthood but that the differentiation of the SBP sex in rhesus monkeys is determined by factors other than prenatal androgen exposure. Steroids 32-39 selenium binding protein 1 Homo sapiens 82-85 223439-7 1979 Among 56 white infants whose mother"s mean BP was above the median for this population, infant sodium intake correlated with infant SBP (r = .31, p less than .009). Sodium 95-101 selenium binding protein 1 Homo sapiens 132-135 7421140-5 1980 This derivative was prepared by coupling 4-hemisuccinamidobiphenyl (4-HSBP) with tyramine, and then radioiodinating this compound using the enzymatic lactoperoxidase method. 4-hemisuccinamidobiphenyl 41-66 selenium binding protein 1 Homo sapiens 70-74 7421140-5 1980 This derivative was prepared by coupling 4-hemisuccinamidobiphenyl (4-HSBP) with tyramine, and then radioiodinating this compound using the enzymatic lactoperoxidase method. Tyramine 81-89 selenium binding protein 1 Homo sapiens 70-74 223439-8 1979 Among 32 black infants, regardless of parents" BP, sodium intake was negatively correlated with SBP (r = -.36, p less than .021). Sodium 51-57 selenium binding protein 1 Homo sapiens 96-99 870953-1 1977 In this report, we describe the chemical interaction between lysergic acid (LSD) and serotonin-binding protein (SBP) by a three-dimensional spectroscopic technique. Lysergic Acid 61-74 selenium binding protein 1 Homo sapiens 85-110 417636-1 1978 We measured the corticosterone and dihydrotestosterone steroid binding capacities of corticosteroid-binding globulin (CBG) and sex steroid plasma binding protein (SBP) throughout pregnancy in seven Macaca nemestrina. Steroids 55-62 selenium binding protein 1 Homo sapiens 163-166 565650-2 1978 The sex steroid binding protein (SBP) of human pregnancy serum was purified to homogeneity by the sequential use of ammonium sulfate precipitation, affinity chromatography on 5alpha-dihydrotestosterone-17beta-succinyldiaminoethyl-(1,4-butanediol diglycidyl ether)-agarose, and preparative polyacrylamide gel electrophoresis. Ammonium Sulfate 116-132 selenium binding protein 1 Homo sapiens 33-36 565650-2 1978 The sex steroid binding protein (SBP) of human pregnancy serum was purified to homogeneity by the sequential use of ammonium sulfate precipitation, affinity chromatography on 5alpha-dihydrotestosterone-17beta-succinyldiaminoethyl-(1,4-butanediol diglycidyl ether)-agarose, and preparative polyacrylamide gel electrophoresis. polyacrylamide 289-303 selenium binding protein 1 Homo sapiens 33-36 565650-4 1978 Homogeneity of SBP was shown by equilibrium sedimentation ultracentrifugation in 6 M guanidine hydrochloride containing 0.1 M mercaptoethanol which yields a minimum molecular weight of 36 335 +/- 525. Guanidine 85-108 selenium binding protein 1 Homo sapiens 15-18 565650-4 1978 Homogeneity of SBP was shown by equilibrium sedimentation ultracentrifugation in 6 M guanidine hydrochloride containing 0.1 M mercaptoethanol which yields a minimum molecular weight of 36 335 +/- 525. Mercaptoethanol 126-141 selenium binding protein 1 Homo sapiens 15-18 565650-7 1978 SBP partially purified from Cohn fraction IV has also a molecular weight of 52 000 by gel electrophoresis in the presence of sodium dodecyl sulfate; that fraction is contaminated with another protein of molecular weight 90 000 which must be removed to obtain homogeneous SBP. Sodium Dodecyl Sulfate 125-147 selenium binding protein 1 Homo sapiens 0-3 649922-1 1978 This study was undertaken to determine whether the ingestion of moderate amounts of ethyl alcohol should be contraindicated in the presence of open-angle glaucoma and/or might interfere with glaucoma detection by methods based on measurement of intraocular pressure (IOP) alone or of the ratios, systolic blood pressure and diastolic blood pressure to intraocular pressure, sBP/IOP and dBP/IOP, respectively. Ethanol 84-97 selenium binding protein 1 Homo sapiens 374-377 649922-3 1978 Ingestation of alcohol resulted in a reduction of IOP, sBP, and dBP. Alcohols 15-22 selenium binding protein 1 Homo sapiens 55-58 870953-1 1977 In this report, we describe the chemical interaction between lysergic acid (LSD) and serotonin-binding protein (SBP) by a three-dimensional spectroscopic technique. Lysergic Acid 61-74 selenium binding protein 1 Homo sapiens 112-115 1257610-0 1976 Is the serotonin binding protein (SBP) a soluble storage form for serotonin? Serotonin 7-16 selenium binding protein 1 Homo sapiens 34-37 59732-10 1976 In experiments with SBP (6-135 nM), the concentrations of unbound testosterone in the superfusion medium were reduced to the same levels as in the experiments with HSA. Testosterone 66-78 selenium binding protein 1 Homo sapiens 20-23 59732-11 1976 The reduction of tissue radioactivity was somewhat larger than that expected from the reduction of unbound testosterone in the superfusion medium for the concentrations of SBP less than 50 nM, and then remained approximately constant. Testosterone 107-119 selenium binding protein 1 Homo sapiens 172-175 59732-12 1976 In addition, SBP altered the metabolism of testosterone: the androstanolone/testosterone ratio in the prostate explants was critically dependent upon the SBP concentration in the superfusion medium. Testosterone 43-55 selenium binding protein 1 Homo sapiens 13-16 59732-12 1976 In addition, SBP altered the metabolism of testosterone: the androstanolone/testosterone ratio in the prostate explants was critically dependent upon the SBP concentration in the superfusion medium. Testosterone 43-55 selenium binding protein 1 Homo sapiens 154-157 59732-12 1976 In addition, SBP altered the metabolism of testosterone: the androstanolone/testosterone ratio in the prostate explants was critically dependent upon the SBP concentration in the superfusion medium. Dihydrotestosterone 61-75 selenium binding protein 1 Homo sapiens 13-16 59732-12 1976 In addition, SBP altered the metabolism of testosterone: the androstanolone/testosterone ratio in the prostate explants was critically dependent upon the SBP concentration in the superfusion medium. Dihydrotestosterone 61-75 selenium binding protein 1 Homo sapiens 154-157 59732-12 1976 In addition, SBP altered the metabolism of testosterone: the androstanolone/testosterone ratio in the prostate explants was critically dependent upon the SBP concentration in the superfusion medium. Testosterone 76-88 selenium binding protein 1 Homo sapiens 13-16 59732-12 1976 In addition, SBP altered the metabolism of testosterone: the androstanolone/testosterone ratio in the prostate explants was critically dependent upon the SBP concentration in the superfusion medium. Testosterone 76-88 selenium binding protein 1 Homo sapiens 154-157 59732-13 1976 It is therefore suggested that, independent of its effect on the binding of testosterone, SBP has a direct effect on testosterone uptake and metabolism by the human prostate. Testosterone 117-129 selenium binding protein 1 Homo sapiens 90-93 322092-4 1977 The highly significant fall in blood pressure (delta SBP and delta DBP) is directly correlated negatively correlated, to the pretreatment pressure (p less than 0.02 for deltaSBP and p less than 0.05 deltaDBP) and negatively correlated to the pindolol plasma level (P less than 0.001 for delta SBP and p less than 0.05 for delta DBP). Pindolol 242-250 selenium binding protein 1 Homo sapiens 53-56 1008515-5 1976 The uptake and metabolism of testosterone were measured and the results suggest that the SBP-testosterone complex could be associated with the prostate cells. Testosterone 29-41 selenium binding protein 1 Homo sapiens 89-92 1008515-5 1976 The uptake and metabolism of testosterone were measured and the results suggest that the SBP-testosterone complex could be associated with the prostate cells. Testosterone 93-105 selenium binding protein 1 Homo sapiens 89-92 1257610-1 1976 The binding of serotonin to a soluble, high affinity binding protein (SBP) present in synaptosomes and assoicated with serotonergic tracts, has now been studied for the effect of drugs and, in particular, drugs interacting with contractile proteins. Serotonin 15-24 selenium binding protein 1 Homo sapiens 70-73 1257610-2 1976 Vincristine, vinblastine, and cytochalasin B were found to cause 50% inhibition of serotonin binding to SBP at 1.5 X 10(-6)M, 7.5 X 10(-6)M and 50 X 10(-6)M, respectively. Vincristine 0-11 selenium binding protein 1 Homo sapiens 104-107 1257610-2 1976 Vincristine, vinblastine, and cytochalasin B were found to cause 50% inhibition of serotonin binding to SBP at 1.5 X 10(-6)M, 7.5 X 10(-6)M and 50 X 10(-6)M, respectively. Vinblastine 13-24 selenium binding protein 1 Homo sapiens 104-107 1257610-2 1976 Vincristine, vinblastine, and cytochalasin B were found to cause 50% inhibition of serotonin binding to SBP at 1.5 X 10(-6)M, 7.5 X 10(-6)M and 50 X 10(-6)M, respectively. Cytochalasin B 30-44 selenium binding protein 1 Homo sapiens 104-107 1257610-2 1976 Vincristine, vinblastine, and cytochalasin B were found to cause 50% inhibition of serotonin binding to SBP at 1.5 X 10(-6)M, 7.5 X 10(-6)M and 50 X 10(-6)M, respectively. Serotonin 83-92 selenium binding protein 1 Homo sapiens 104-107 1257610-3 1976 Colchicine did not affect the binding at 1 X 10(-3)M. When vinblastine was injected intraventricularly, the binding capacity of SBP isolated from brain 20 and 26 hours after injection was decreased 42% and 60% respectively. Vinblastine 59-70 selenium binding protein 1 Homo sapiens 128-131 6029668-0 1967 Toxicological studies with a hydrocarbon solvent, SBP 62/82. Hydrocarbons 29-40 selenium binding protein 1 Homo sapiens 50-53 235485-1 1975 I. Elasmobranch steroids-binding protein (E. SBP) in dogfish serum (Scyliorhinus canicula). Steroids 16-24 selenium binding protein 1 Homo sapiens 45-48 51854-11 1975 The second binding component was attributable, at least in part, to the sex steroid-binding plasma protein (SBP), as indicated by its sedimentation coefficient (congruent to 4 S in low salt medium), its high affinity for androstanolone and androstanediol and its lower affinity for estradiol, and finally, its migration on polyacrylamide gel electrophoresis. Dihydrotestosterone 221-235 selenium binding protein 1 Homo sapiens 76-106 51854-11 1975 The second binding component was attributable, at least in part, to the sex steroid-binding plasma protein (SBP), as indicated by its sedimentation coefficient (congruent to 4 S in low salt medium), its high affinity for androstanolone and androstanediol and its lower affinity for estradiol, and finally, its migration on polyacrylamide gel electrophoresis. Dihydrotestosterone 221-235 selenium binding protein 1 Homo sapiens 108-111 51854-11 1975 The second binding component was attributable, at least in part, to the sex steroid-binding plasma protein (SBP), as indicated by its sedimentation coefficient (congruent to 4 S in low salt medium), its high affinity for androstanolone and androstanediol and its lower affinity for estradiol, and finally, its migration on polyacrylamide gel electrophoresis. Androstane-3,17-diol 240-254 selenium binding protein 1 Homo sapiens 76-106 51854-11 1975 The second binding component was attributable, at least in part, to the sex steroid-binding plasma protein (SBP), as indicated by its sedimentation coefficient (congruent to 4 S in low salt medium), its high affinity for androstanolone and androstanediol and its lower affinity for estradiol, and finally, its migration on polyacrylamide gel electrophoresis. Androstane-3,17-diol 240-254 selenium binding protein 1 Homo sapiens 108-111 51854-11 1975 The second binding component was attributable, at least in part, to the sex steroid-binding plasma protein (SBP), as indicated by its sedimentation coefficient (congruent to 4 S in low salt medium), its high affinity for androstanolone and androstanediol and its lower affinity for estradiol, and finally, its migration on polyacrylamide gel electrophoresis. Estradiol 282-291 selenium binding protein 1 Homo sapiens 76-106 51854-11 1975 The second binding component was attributable, at least in part, to the sex steroid-binding plasma protein (SBP), as indicated by its sedimentation coefficient (congruent to 4 S in low salt medium), its high affinity for androstanolone and androstanediol and its lower affinity for estradiol, and finally, its migration on polyacrylamide gel electrophoresis. Estradiol 282-291 selenium binding protein 1 Homo sapiens 108-111 51854-11 1975 The second binding component was attributable, at least in part, to the sex steroid-binding plasma protein (SBP), as indicated by its sedimentation coefficient (congruent to 4 S in low salt medium), its high affinity for androstanolone and androstanediol and its lower affinity for estradiol, and finally, its migration on polyacrylamide gel electrophoresis. polyacrylamide 323-337 selenium binding protein 1 Homo sapiens 76-106 51854-11 1975 The second binding component was attributable, at least in part, to the sex steroid-binding plasma protein (SBP), as indicated by its sedimentation coefficient (congruent to 4 S in low salt medium), its high affinity for androstanolone and androstanediol and its lower affinity for estradiol, and finally, its migration on polyacrylamide gel electrophoresis. polyacrylamide 323-337 selenium binding protein 1 Homo sapiens 108-111 51854-12 1975 In one instance, the concentration of the SBP-like protein in prostate cytosol was measured by equilibrium dialysis, and it was calculated that the binding capacity of the prostate SBP-like component corresponded to 4 pmol of androstanolone/g of prostate, a small (less than 5%) value with regard to SBP concentration in the plasma of the same patient. Dihydrotestosterone 226-240 selenium binding protein 1 Homo sapiens 42-45 51854-12 1975 In one instance, the concentration of the SBP-like protein in prostate cytosol was measured by equilibrium dialysis, and it was calculated that the binding capacity of the prostate SBP-like component corresponded to 4 pmol of androstanolone/g of prostate, a small (less than 5%) value with regard to SBP concentration in the plasma of the same patient. Dihydrotestosterone 226-240 selenium binding protein 1 Homo sapiens 181-184 51854-12 1975 In one instance, the concentration of the SBP-like protein in prostate cytosol was measured by equilibrium dialysis, and it was calculated that the binding capacity of the prostate SBP-like component corresponded to 4 pmol of androstanolone/g of prostate, a small (less than 5%) value with regard to SBP concentration in the plasma of the same patient. Dihydrotestosterone 226-240 selenium binding protein 1 Homo sapiens 181-184 51854-16 1975 In the peak containing the SBP-like protein, the ratio was 0.74, which may suggest that all or part had been exposed to the predominant androstanolone environment inside the prostatic cell. Dihydrotestosterone 136-150 selenium binding protein 1 Homo sapiens 27-30 33830460-8 2021 SBP and DBP goals were achieved by 35.9% and 47.3% of patients on telmisartan monotherapy and by 35.9% and 46.8% of patients on telmisartan + 1 AHD. Telmisartan 66-77 selenium binding protein 1 Homo sapiens 0-3 33830460-8 2021 SBP and DBP goals were achieved by 35.9% and 47.3% of patients on telmisartan monotherapy and by 35.9% and 46.8% of patients on telmisartan + 1 AHD. Telmisartan 128-139 selenium binding protein 1 Homo sapiens 0-3 33830460-10 2021 SBP and DBP goals were achieved by 31.7% and 39.7% of patients on telmisartan monotherapy and by 31.9% and 41.8% of patients on telmisartan + 1 AHD. Telmisartan 66-77 selenium binding protein 1 Homo sapiens 0-3 33830460-10 2021 SBP and DBP goals were achieved by 31.7% and 39.7% of patients on telmisartan monotherapy and by 31.9% and 41.8% of patients on telmisartan + 1 AHD. Telmisartan 128-139 selenium binding protein 1 Homo sapiens 0-3 34054053-7 2021 As the reduction of systolic ARV was majorly derived from the change of mean SBP, diastolic ARV was significantly determined by urinary sodium-to-potassium ratio (beta coefficient +- standard error: 0.012 +- 0.004; P = 0.006) after adjusting for age, sex, smoking, mean DBP, BMI, and race. Sodium 136-142 selenium binding protein 1 Homo sapiens 77-80 33610053-8 2021 In all of many comparisons higher PFAS exposure (apart from PFHxS) was associated with higher systolic (SBP) and diastolic (DBP) blood pressures, although not all were significant, which is unlikely to be due to chance. pfas 34-38 selenium binding protein 1 Homo sapiens 104-107 33610053-9 2021 After adjustment, each doubling in PFOS or PFOA exposure was associated with 0.47 mmHg (95% CI: -0.13; 1.08) and 0.36 mmHg (-0.19; 0.92) higher SBP; and 0.58 mmHg (0.13; 1.04) and 0.37 mmHg (-0.05; 0.79) higher DBP. perfluorooctane sulfonic acid 35-39 selenium binding protein 1 Homo sapiens 144-147 33610053-9 2021 After adjustment, each doubling in PFOS or PFOA exposure was associated with 0.47 mmHg (95% CI: -0.13; 1.08) and 0.36 mmHg (-0.19; 0.92) higher SBP; and 0.58 mmHg (0.13; 1.04) and 0.37 mmHg (-0.05; 0.79) higher DBP. perfluorooctanoic acid 43-47 selenium binding protein 1 Homo sapiens 144-147 32909966-8 2021 Our analysis has demonstrated a slight superiority for chlorthalidone regarding SBP and not statistically significant differences regarding DBP. Chlorthalidone 55-69 selenium binding protein 1 Homo sapiens 80-83 32676938-7 2021 The factors influencing glutathione peroxidase activity in patients with T2DM were creatinine (CREA; beta = - 0.378; P < 0.001), uric acid (beta = - 0.069; P = 0.009), body mass index (beta = - 2.177; P = 0.002), SBP (beta = - 0.275; P = 0.031), and medical payment (beta = 29.160; P < 0.001). Glutathione 24-35 selenium binding protein 1 Homo sapiens 213-216 33987149-8 2021 Additionally, fish oil supplementation significantly lowered systolic blood pressure (SBP, MD: -2.46 mmHg, 95% CI: -4.93 to -0.01, P = 0.04) but did not significantly change diastolic blood pressure (P = 0.22). Fish Oils 14-22 selenium binding protein 1 Homo sapiens 86-89 33987149-10 2021 Conclusions: In overweight or obese children and adolescents, supplementation with fish oil could reduce BMI, decrease serum triglyceride, and lower SBP, while serum cholesterol and fasting glucose may not be significantly affected. Fish Oils 83-91 selenium binding protein 1 Homo sapiens 149-152 33907880-9 2021 SELENBP1 knockdown enhances resistance of OSCC cells to 5-FU and cisplatin, while SENENBP1 overexpression displays the opposite effects. Fluorouracil 56-60 selenium binding protein 1 Homo sapiens 0-8 33907880-9 2021 SELENBP1 knockdown enhances resistance of OSCC cells to 5-FU and cisplatin, while SENENBP1 overexpression displays the opposite effects. Cisplatin 65-74 selenium binding protein 1 Homo sapiens 0-8 33907880-12 2021 Downregulation of SELENBP1 is induced by miR-4786-3p binding to the 3" untranslated region (UTR) of SELENBP1. mir-4786-3p 41-52 selenium binding protein 1 Homo sapiens 18-26 33907880-12 2021 Downregulation of SELENBP1 is induced by miR-4786-3p binding to the 3" untranslated region (UTR) of SELENBP1. mir-4786-3p 41-52 selenium binding protein 1 Homo sapiens 100-108 33790397-8 2021 (3) BaPWV was negatively associated with 25(OH)D (r = -0.12, P = 0.004), while positively associated with age, duration of diabetes, HR, SBP, and low-density lipoprotein cholesterol and negatively associated with body weight and BMI (all P < 0.05). bapwv 4-9 selenium binding protein 1 Homo sapiens 137-140 33548850-15 2021 The high-exposure groups, characterized by higher metal concentrations, had significant higher GGT, SBP, DBP, and mortality rates suggesting the detrimental effects of exposure to these heavy metals. Metals 50-55 selenium binding protein 1 Homo sapiens 100-103 33199881-9 2021 The antihypertensive effect of esaxerenone on SBP was significantly greater in females and in patients receiving monotherapy. esaxerenone 31-42 selenium binding protein 1 Homo sapiens 46-49 32804345-8 2021 We noticed a relationship between 1-year mean percentage changes of serum 25OHD and SBP levels (R = - 0.36, p < 0.05). 25ohd 74-79 selenium binding protein 1 Homo sapiens 84-87 32804345-9 2021 CONCLUSION: One-year cholecalciferol supplementation, able to restore D status, significantly improves FG, HbA1c, SBP and HDL-cholesterol levels in patients with poor-controlled type 2 diabetes mellitus and D deficiency. Cholecalciferol 21-36 selenium binding protein 1 Homo sapiens 114-117 33790397-10 2021 Logistic regression showed that age and SBP were risk factor of AS (OR:1.07, 95% CI: 1.05-1.10, P < 0.001; OR:1.03, 95% CI: 1.02-1.04, P < 0.001) while 25(OH)D was protective factor of AS (OR:0.987, 95% CI: 0.976-0.998, P = 0.024). 25(oh)d 152-159 selenium binding protein 1 Homo sapiens 40-43 32710438-10 2021 After careful analysis, 34 randomized and double-blind clinical trials were included to investigate the efficacy of nebivolol on systolic (SBP) and diastolic blood pressure (DBP) control and adverse effects. Nebivolol 116-125 selenium binding protein 1 Homo sapiens 139-142 33734049-6 2021 However, the decrease in average daily SBP was almost 4 times greater in the rfAH group than in the ucAH group ( -19.9 and -5.1 mm Hg, respectively, r=0.02). rfah 77-81 selenium binding protein 1 Homo sapiens 39-42 33737848-10 2021 Results: We found 24-hour urinary norepinephrine levels were associated with systolic and diastolic BP (SBP, beta=0.157, p=0.082; DBP, beta=0.212, p=0.023) and mean arterial pressure (MAP, beta=0.198, p=0.032) after adjusting for confounders. Norepinephrine 34-48 selenium binding protein 1 Homo sapiens 104-107 33737848-12 2021 After adjusting for confounders, increased 24-hour urinary norepinephrine levels were significantly associated with elevated SBP (beta=0.454, p=0.012), DBP (beta=0.399, p=0.041), and MAP (beta=0.432, p=0.023) in normal weight, but not in overweight/obese patients (all p>0.2). Norepinephrine 59-73 selenium binding protein 1 Homo sapiens 125-128 33673622-9 2021 Treatment of SELENBP1 knock-down cells with the H2S donor GYY4137 partially restored lipid accumulation, increased cellular H2S levels, and exerted a bell-shaped effect on cellular bioenergetics (enhancement at 1 and 3 mM, and inhibition at 6 mM). Deuterium 48-51 selenium binding protein 1 Homo sapiens 13-21 33418065-9 2021 Systolic blood pressure was only associated with an increasing EPA to DHA ratio in the 2 g to 6 g range (beta = 5.47129 and 95% CI: 0.40677 to 10.53580), that is, a higher EPA to DHA ratio within this dose range, the greater the increase in SBP. Eicosapentaenoic Acid 63-66 selenium binding protein 1 Homo sapiens 241-244 33673622-0 2021 Selenium-Binding Protein 1 (SELENBP1) Supports Hydrogen Sulfide Biosynthesis and Adipogenesis. Hydrogen Sulfide 47-63 selenium binding protein 1 Homo sapiens 0-26 33673622-0 2021 Selenium-Binding Protein 1 (SELENBP1) Supports Hydrogen Sulfide Biosynthesis and Adipogenesis. Hydrogen Sulfide 47-63 selenium binding protein 1 Homo sapiens 28-36 33673622-9 2021 Treatment of SELENBP1 knock-down cells with the H2S donor GYY4137 partially restored lipid accumulation, increased cellular H2S levels, and exerted a bell-shaped effect on cellular bioenergetics (enhancement at 1 and 3 mM, and inhibition at 6 mM). GYY 4137 58-65 selenium binding protein 1 Homo sapiens 13-21 33673622-3 2021 However, recently, a fourth H2S-producing enzyme, selenium-binding-protein 1 (SELENBP1), has also been identified. Deuterium 28-31 selenium binding protein 1 Homo sapiens 50-76 33673622-3 2021 However, recently, a fourth H2S-producing enzyme, selenium-binding-protein 1 (SELENBP1), has also been identified. Deuterium 28-31 selenium binding protein 1 Homo sapiens 78-86 33673622-9 2021 Treatment of SELENBP1 knock-down cells with the H2S donor GYY4137 partially restored lipid accumulation, increased cellular H2S levels, and exerted a bell-shaped effect on cellular bioenergetics (enhancement at 1 and 3 mM, and inhibition at 6 mM). Deuterium 124-127 selenium binding protein 1 Homo sapiens 13-21 33673622-8 2021 SELENBP1 silencing decreased cellular H2S levels, suppressed the expression of the three "classical" H2S-producing enzymes (CBS, CSE, and 3-MST) and significantly suppressed adipocyte differentiation. Deuterium 38-41 selenium binding protein 1 Homo sapiens 0-8 33673622-8 2021 SELENBP1 silencing decreased cellular H2S levels, suppressed the expression of the three "classical" H2S-producing enzymes (CBS, CSE, and 3-MST) and significantly suppressed adipocyte differentiation. Deuterium 101-104 selenium binding protein 1 Homo sapiens 0-8 33673622-10 2021 We conclude that SELENBP1 in adipocytes (1) contributes to H2S biosynthesis and (2) acts as an endogenous stimulator of adipocyte differentiation. Deuterium 59-62 selenium binding protein 1 Homo sapiens 17-25 33342240-6 2021 Subsequent pathway analysis showed that metabolic pathways of long-chain saturated acylcarnitine, phosphatidylinositol, and sphingomyelins were associated with SBP and DBP (false discovery rate-adjusted Fisher exact test P<0.05). acylcarnitine 83-96 selenium binding protein 1 Homo sapiens 160-163 33583418-4 2021 RESULTS: The following metal exposure biomarkers were conditionally predictive of SBP and/or DBP in the full sample: antimony (Sb), barium (Ba), cadmium (Cd), cesium (Cs), lead (Pb), tungsten (W) and molybdenum (Mo). Metals 23-28 selenium binding protein 1 Homo sapiens 82-85 33583418-4 2021 RESULTS: The following metal exposure biomarkers were conditionally predictive of SBP and/or DBP in the full sample: antimony (Sb), barium (Ba), cadmium (Cd), cesium (Cs), lead (Pb), tungsten (W) and molybdenum (Mo). Antimony 127-129 selenium binding protein 1 Homo sapiens 82-85 33583418-4 2021 RESULTS: The following metal exposure biomarkers were conditionally predictive of SBP and/or DBP in the full sample: antimony (Sb), barium (Ba), cadmium (Cd), cesium (Cs), lead (Pb), tungsten (W) and molybdenum (Mo). Barium 132-138 selenium binding protein 1 Homo sapiens 82-85 33583418-4 2021 RESULTS: The following metal exposure biomarkers were conditionally predictive of SBP and/or DBP in the full sample: antimony (Sb), barium (Ba), cadmium (Cd), cesium (Cs), lead (Pb), tungsten (W) and molybdenum (Mo). Barium 140-142 selenium binding protein 1 Homo sapiens 82-85 33583418-5 2021 The highest average SBP (> 120 mmHg) was observed among those with low Sb (<= 0.21 mug/dL) high Cd (> 0.22 mug/g creatinine) and high Pb (> 2.55 mug/dL) biomarkers. Cadmium 96-98 selenium binding protein 1 Homo sapiens 20-23 33583418-5 2021 The highest average SBP (> 120 mmHg) was observed among those with low Sb (<= 0.21 mug/dL) high Cd (> 0.22 mug/g creatinine) and high Pb (> 2.55 mug/dL) biomarkers. Creatinine 113-123 selenium binding protein 1 Homo sapiens 20-23 33583418-5 2021 The highest average SBP (> 120 mmHg) was observed among those with low Sb (<= 0.21 mug/dL) high Cd (> 0.22 mug/g creatinine) and high Pb (> 2.55 mug/dL) biomarkers. Lead 134-136 selenium binding protein 1 Homo sapiens 20-23 33838996-11 2021 CONCLUSIONS: Sodium restriction significantly reduces SBP and DBP in patients with T2DM. Sodium 13-19 selenium binding protein 1 Homo sapiens 54-57 33665198-14 2021 BMI and SBP, as chain mediators, multiply and chain mediated the effect of TC levels on IADL. Technetium 75-77 selenium binding protein 1 Homo sapiens 8-11 33580564-5 2021 RESULTS: Average 24-hr SBP increased with T treatment (testosterone*time, P=0.035). Testosterone 55-67 selenium binding protein 1 Homo sapiens 23-26 33455057-9 2021 SBP was positively associated with MIBC and BC-specific mortality in an analysis of never-smokers, which may reflect the association, un-confounded by smoking, also in a broader population. 4-METHYL-2-PENTANOL 35-39 selenium binding protein 1 Homo sapiens 0-3 33342240-6 2021 Subsequent pathway analysis showed that metabolic pathways of long-chain saturated acylcarnitine, phosphatidylinositol, and sphingomyelins were associated with SBP and DBP (false discovery rate-adjusted Fisher exact test P<0.05). Phosphatidylinositols 98-118 selenium binding protein 1 Homo sapiens 160-163 33342240-6 2021 Subsequent pathway analysis showed that metabolic pathways of long-chain saturated acylcarnitine, phosphatidylinositol, and sphingomyelins were associated with SBP and DBP (false discovery rate-adjusted Fisher exact test P<0.05). Sphingomyelins 124-138 selenium binding protein 1 Homo sapiens 160-163 32814612-6 2021 The high detection (>=0 4 %) and recognition (>1 6 %) thresholds of salt taste were associated with higher salt intake scores for Akita men aged 30-59 years, whose detection and recognition thresholds tended be positively associated with systolic and diastolic blood pressures (SBP and DBP) after adjustment for potential confounders. Salts 68-72 selenium binding protein 1 Homo sapiens 278-281 32776714-8 2021 Among adolescents with obesity, C-DII quartile was associated with higher SBP (beta = 5.07, 95% CI 2.55-7.59) and lower DBP (beta = -4.14, 95% CI -6.74, -1.54). c-dii 32-37 selenium binding protein 1 Homo sapiens 74-77 32809982-10 2021 Most studies in transgender men did not demonstrate a change in BP, whereas transgender women on GHT demonstrated an increase in SBP but not DBP. 6a,7-Dehydroboldine 97-100 selenium binding protein 1 Homo sapiens 129-132 33534342-10 2021 CONCLUSION: Among patients with HFpEF, long-term control of SBP level at 120-129 mmHg is independently associated with the highest risk reduction of all-cause mortality and improvement of KCCQ score. kccq 188-192 selenium binding protein 1 Homo sapiens 60-63 33534343-5 2021 RESULTS: Plasma cortisol at 1600 h, 24 h-UFC, and UFC/U creat were significantly and positively correlated with daytime, night-time, and 24-h SBP; plasma cortisol at 0800 h was not associated with BP. Hydrocortisone 16-24 selenium binding protein 1 Homo sapiens 142-145 32773651-4 2021 Effects of vitamin D on SBP or DBP were analyzed using mixed-effects models. Vitamin D 11-20 selenium binding protein 1 Homo sapiens 24-27 33459937-12 2021 The dietary salt equivalent of patients in group 1 correlated positively with 24-h SBP and mean arterial pressure (MAP) values. Sodium Chloride, Dietary 4-16 selenium binding protein 1 Homo sapiens 83-86 33434556-4 2021 RESULTS: Mean systolic/diastolic blood pressure (SBP/DBP) reduction with HCTZ vs chlorthalidone: 8+-8/4+-5 vs 12+-9/7+-5 mmHg in whites (p<10-6 SBP and DBP); 12+-10/7+-6 vs 15+-10/9+-6 in blacks (p=0.008 SBP, p=0.054 DBP). Hydrochlorothiazide 73-77 selenium binding protein 1 Homo sapiens 49-52 33434556-4 2021 RESULTS: Mean systolic/diastolic blood pressure (SBP/DBP) reduction with HCTZ vs chlorthalidone: 8+-8/4+-5 vs 12+-9/7+-5 mmHg in whites (p<10-6 SBP and DBP); 12+-10/7+-6 vs 15+-10/9+-6 in blacks (p=0.008 SBP, p=0.054 DBP). Hydrochlorothiazide 73-77 selenium binding protein 1 Homo sapiens 144-147 33434556-4 2021 RESULTS: Mean systolic/diastolic blood pressure (SBP/DBP) reduction with HCTZ vs chlorthalidone: 8+-8/4+-5 vs 12+-9/7+-5 mmHg in whites (p<10-6 SBP and DBP); 12+-10/7+-6 vs 15+-10/9+-6 in blacks (p=0.008 SBP, p=0.054 DBP). Hydrochlorothiazide 73-77 selenium binding protein 1 Homo sapiens 144-147 32971315-4 2021 RESULTS: A large part of the variance in SBP (31.6%) was explained by the regression on a z unit-weighted composite score (based on LOOH, AOPP, SOD, NOx) reflecting nitro-oxidative stress toxicity (NOSTOX), coupled with highly sensitive C-reactive protein, body weight and use of antihypertensives. Lipid Peroxides 132-136 selenium binding protein 1 Homo sapiens 41-44 32971315-6 2021 The most important O&NS biomarkers predicting an increased SBP were in descending order of significance: LOOH, AOPP and SOD. Nitrogen 21-23 selenium binding protein 1 Homo sapiens 59-62 32971315-6 2021 The most important O&NS biomarkers predicting an increased SBP were in descending order of significance: LOOH, AOPP and SOD. Lipid Peroxides 105-109 selenium binding protein 1 Homo sapiens 59-62 33505995-12 2020 Nebivolol reduced SBP and DBP by 7.6 and 6.6 mmHg, respectively, in 4 weeks, and by 11.1 and 8.0 mm Hg, respectively, in 8 weeks. Nebivolol 0-9 selenium binding protein 1 Homo sapiens 18-21 33423824-7 2021 In the comparison of the figures for the DEX group with the DZP (143.85+-2.30-137.95+-5.62) the SBP was significant with a (p=.0001). Dexmedetomidine 41-44 selenium binding protein 1 Homo sapiens 96-99 33206572-4 2021 RESULTS: Valsartan regimens resulted in mean(SD) systolic (SBP) and diastolic (DBP) reductions of 18.0(15.8)mmHg and 9.5(10.1)mmHg, respectively, at ~90 days; yielding SBP, DBP and combined SBP/DBP control rates of 44.0%, 67.2% and 39.3%, respectively. Valsartan 9-18 selenium binding protein 1 Homo sapiens 59-62 33206572-4 2021 RESULTS: Valsartan regimens resulted in mean(SD) systolic (SBP) and diastolic (DBP) reductions of 18.0(15.8)mmHg and 9.5(10.1)mmHg, respectively, at ~90 days; yielding SBP, DBP and combined SBP/DBP control rates of 44.0%, 67.2% and 39.3%, respectively. Valsartan 9-18 selenium binding protein 1 Homo sapiens 168-171 33206572-4 2021 RESULTS: Valsartan regimens resulted in mean(SD) systolic (SBP) and diastolic (DBP) reductions of 18.0(15.8)mmHg and 9.5(10.1)mmHg, respectively, at ~90 days; yielding SBP, DBP and combined SBP/DBP control rates of 44.0%, 67.2% and 39.3%, respectively. Valsartan 9-18 selenium binding protein 1 Homo sapiens 168-171 33186315-8 2021 Independent predictors of low-MEE were older age, higher SBP, diabetes mellitus, LV concentric geometry and lower LV systolic function. low-mee 26-33 selenium binding protein 1 Homo sapiens 57-60 32665523-6 2020 Higher SBP was associated with worse reasoning (0.034 SDs) and matrix completion scores (-0.024 SDs; both P < 0.001). Sodium Dodecyl Sulfate 54-57 selenium binding protein 1 Homo sapiens 7-10 34009196-5 2020 Results showed that the combined therapy (HU + L-Arginine) decreased SBP, DBP, MAP and PP (p <0.01 in each case) but increased %HbF, Hb and PCV (p< o.001 in each case). Hydroxyurea 42-44 selenium binding protein 1 Homo sapiens 69-72 34009196-5 2020 Results showed that the combined therapy (HU + L-Arginine) decreased SBP, DBP, MAP and PP (p <0.01 in each case) but increased %HbF, Hb and PCV (p< o.001 in each case). Arginine 47-57 selenium binding protein 1 Homo sapiens 69-72 32608283-5 2020 Correlations between the CL-BP and C-BP measurements were sought using Pearson"s correlation coefficients and Bland-Altman plots.Results: Using the C-BP device, the 24 h SBP value for the cohort was 125.4 +- 10.9 mmHg (mean +- SD); the corresponding DBP value being 75 +- 8.3 mmHg. cl-bp 25-30 selenium binding protein 1 Homo sapiens 170-173 32608283-6 2020 Mean SBP/DBP were higher with the CL-BP device, i.e. 131.1 +- 15.9/80.2 +- 9.7 mmHg . cl-bp 34-39 selenium binding protein 1 Homo sapiens 5-8 32608283-8 2020 Better correlations for SBP and DBP were found 1) in patients with BMI > 25 (SBP: r = 0.65, DBP: r = 0.70) compared to those with BMI <25 and 2) in males compared to females (SBP: r = 0.71, DBP: r = 0.77).Conclusions: In our patients a CL-BP device estimated 24 h mean SBP and DBP differently from the classical oscillometric device, with a moderate correlation. cl-bp 236-241 selenium binding protein 1 Homo sapiens 24-27 32333720-6 2020 The association between the presence of the LPSB with the pneumatization type of the sphenoid sinus and the presence of a LRSS was evaluated. lrss 122-126 selenium binding protein 1 Homo sapiens 44-48 32901435-11 2020 SBP and DBP goals were achieved by 31.4% and 42.9% of patients on amlodipine monotherapy and by 38.9% and 51.8% of patients on amlodipine + 1AHD, respectively. Amlodipine 66-76 selenium binding protein 1 Homo sapiens 0-3 32901435-11 2020 SBP and DBP goals were achieved by 31.4% and 42.9% of patients on amlodipine monotherapy and by 38.9% and 51.8% of patients on amlodipine + 1AHD, respectively. Amlodipine 127-137 selenium binding protein 1 Homo sapiens 0-3 32901435-13 2020 SBP and DBP goals were achieved by 35.4% and 33.8% of patients on amlodipine monotherapy and by 48.0% and 56.0% of patients on amlodipine + 1AHD, respectively. Amlodipine 66-76 selenium binding protein 1 Homo sapiens 0-3 32901435-13 2020 SBP and DBP goals were achieved by 35.4% and 33.8% of patients on amlodipine monotherapy and by 48.0% and 56.0% of patients on amlodipine + 1AHD, respectively. Amlodipine 127-137 selenium binding protein 1 Homo sapiens 0-3 32901435-15 2020 SBP and DBP goals were achieved by 25.5% and 13.7% of patients on amlodipine monotherapy and by 29.8% and 14.0% of patients on amlodipine + 1AHD. Amlodipine 66-76 selenium binding protein 1 Homo sapiens 0-3 32901435-15 2020 SBP and DBP goals were achieved by 25.5% and 13.7% of patients on amlodipine monotherapy and by 29.8% and 14.0% of patients on amlodipine + 1AHD. Amlodipine 127-137 selenium binding protein 1 Homo sapiens 0-3 32665523-6 2020 Higher SBP was associated with worse reasoning (0.034 SDs) and matrix completion scores (-0.024 SDs; both P < 0.001). Sodium Dodecyl Sulfate 96-99 selenium binding protein 1 Homo sapiens 7-10 32569700-8 2020 There were greater reductions with canagliflozin versus placebo for HbA1c (-0.75% versus -0.58%; P = .0091), SBP (-6.26 versus -3.83 mmHg; P = .0018), and body weight (-3.79 versus -2.18 kg; P < .0001) in those on baseline GLP1-RA therapy. Canagliflozin 35-48 selenium binding protein 1 Homo sapiens 109-112 33170247-13 2020 Candesartan reduced SBP by -6.56 mm Hg (P < .001; n = 240). candesartan 0-11 selenium binding protein 1 Homo sapiens 20-23 33230755-7 2020 SBP/DBP increased in most nicotine e-cig arms, in some non-nicotine e-cig arms, and in none of the placebo arms. Nicotine 26-34 selenium binding protein 1 Homo sapiens 0-3 33230755-9 2020 The use of e-cigs with and without nicotine may result in short-term elevations of both SBP and DBP. Nicotine 35-43 selenium binding protein 1 Homo sapiens 88-91 33083372-7 2020 Indeed, diets high in monounsaturated fatty acids more effective in reducing both SBP and DBP than high-carbohydrate diets, whereas high-protein diets were not effective. Fatty Acids, Monounsaturated 22-49 selenium binding protein 1 Homo sapiens 82-85 32696115-5 2020 Increasing DBP increased the risk of developing both PDR and DME (p < 0.0001), whereas increasing SBP increased the risk of developing DME (p < 0.0001), but not PDR (p > 0.08). dme 135-138 selenium binding protein 1 Homo sapiens 98-101 32649634-9 2020 Among females, for each kilogramme of birth weight, there was a predicted decrease of 1.59 (0.7, 2.5) mmHg in SBP, P = 0.001 and 0.85 (0.2, 1.5) mmHg in DBP, P = 0.001; after adjustments for age, body size, physical activity, smoking status, alcohol intake and socioeconomic factors. Alcohols 242-249 selenium binding protein 1 Homo sapiens 110-113 33879436-8 2020 GLP1 levels and SBP were also found to be positively correlated with serum DPP4 levels in NDD group (p<0.05). Nordazepam 90-93 selenium binding protein 1 Homo sapiens 16-19 32811735-8 2020 Analyses in black men, split by self-reported alcohol use and smoking, revealed 24 h blood pressure-PAI-1act associations only in alcohol users (24 h SBP [B = 4.22, p < 0.001], DBP [B = 2.04, p = 0.015] and PP [B = 2.18, p = 0.013]) and smokers (24 h SBP [B = 6.10, p < 0.001] and PP [B = 4.33, p = 0.001]). Alcohols 130-137 selenium binding protein 1 Homo sapiens 150-153 32811735-8 2020 Analyses in black men, split by self-reported alcohol use and smoking, revealed 24 h blood pressure-PAI-1act associations only in alcohol users (24 h SBP [B = 4.22, p < 0.001], DBP [B = 2.04, p = 0.015] and PP [B = 2.18, p = 0.013]) and smokers (24 h SBP [B = 6.10, p < 0.001] and PP [B = 4.33, p = 0.001]). Alcohols 130-137 selenium binding protein 1 Homo sapiens 251-254 33083372-9 2020 Overall, the results of our meta-analysis show that diets high in monounsaturated fatty acids are more effective in reducing both SBP and DBP than diets high in carbohydrate, whereas other dietary approaches were not effective. Fatty Acids, Monounsaturated 66-93 selenium binding protein 1 Homo sapiens 130-133 32958007-8 2020 RESULTS: Both SBP and DBP increased significantly with an increase in the ln-transformed serum PFAS concentrations in a monotonic way. pfas 95-99 selenium binding protein 1 Homo sapiens 14-17 31902603-6 2020 Dose-response analysis revealed that phytosterol intake change SBP significantly based on treatment dose in nonlinear fashion. Phytosterols 37-48 selenium binding protein 1 Homo sapiens 63-66 33106215-6 2020 MOPP was calculated using the formula MOPP = 2/3 [DBP + 1/3 (SBP - DBP)] - IOP. mopp 0-4 selenium binding protein 1 Homo sapiens 61-64 33106215-6 2020 MOPP was calculated using the formula MOPP = 2/3 [DBP + 1/3 (SBP - DBP)] - IOP. mopp 38-42 selenium binding protein 1 Homo sapiens 61-64 32398581-17 2020 Performance error calculations showed that SBP was maintained closer to baseline with the norepinephrine infusion. Norepinephrine 90-104 selenium binding protein 1 Homo sapiens 43-46 31902603-7 2020 Subgroup analysis based on duration showed a significant effect of phytosterol on SBP and DBP in subsets of <12 weeks. Phytosterols 67-78 selenium binding protein 1 Homo sapiens 82-85 31902603-8 2020 In addition, a significant effect of phytosterol was observed in dosage of >=2000 mg for SBP and <2000 mg for DBP. Phytosterols 37-48 selenium binding protein 1 Homo sapiens 89-92 32618884-1 2020 BACKGROUND: The sodium-glucose co-transporter 2 (SGLT2) inhibitor empagliflozin reduced cardiovascular death or heart failure hospitalizations in type 2 diabetes (T2D) in addition to a reduction of SBP. empagliflozin 66-79 selenium binding protein 1 Homo sapiens 198-201 32453015-2 2020 METHODS: SBP was measured in 9051 primary care patients in England on DOACs for atrial fibrillation with postinitiation BP levels available within the Clinical Practice Research Datalink. doacs 70-75 selenium binding protein 1 Homo sapiens 9-12 32453015-7 2020 CONCLUSION: SBP values below 161 mmHg are associated higher all-cause mortality, but lower event risk in patients with atrial fibrillation on DOAC therapy. 1-(4-acetyl-2,5-dimethoxyphenyl)-2-aminopropane 142-146 selenium binding protein 1 Homo sapiens 12-15 32516287-6 2020 SNPs rs12042763 in the COX-2 gene was significantly associated with SBP responses to both low-salt and high-salt diet. Salts 94-98 selenium binding protein 1 Homo sapiens 68-71 32516287-6 2020 SNPs rs12042763 in the COX-2 gene was significantly associated with SBP responses to both low-salt and high-salt diet. Salts 108-112 selenium binding protein 1 Homo sapiens 68-71 32516289-7 2020 RESULTS: During a median follow-up of 51.8 (40.5-56.2) months, the incidences of all-cause death and composite outcomes were higher in the high SBP-ARV group than in the low SBP-ARV group. omega-N-Allylarginine 148-151 selenium binding protein 1 Homo sapiens 144-147 32618884-2 2020 As heart failure patients often present with low SBP, which can challenge treatment initiation, we explored if empagliflozin"s effect on SBP was independent of baseline SBP and heart failure status, and if the effect on cardiovascular and heart failure outcomes was influenced by updated mean SBP or by an early change in SBP after drug initiation. empagliflozin 111-124 selenium binding protein 1 Homo sapiens 137-140 32618884-2 2020 As heart failure patients often present with low SBP, which can challenge treatment initiation, we explored if empagliflozin"s effect on SBP was independent of baseline SBP and heart failure status, and if the effect on cardiovascular and heart failure outcomes was influenced by updated mean SBP or by an early change in SBP after drug initiation. empagliflozin 111-124 selenium binding protein 1 Homo sapiens 137-140 32618884-2 2020 As heart failure patients often present with low SBP, which can challenge treatment initiation, we explored if empagliflozin"s effect on SBP was independent of baseline SBP and heart failure status, and if the effect on cardiovascular and heart failure outcomes was influenced by updated mean SBP or by an early change in SBP after drug initiation. empagliflozin 111-124 selenium binding protein 1 Homo sapiens 137-140 32618884-2 2020 As heart failure patients often present with low SBP, which can challenge treatment initiation, we explored if empagliflozin"s effect on SBP was independent of baseline SBP and heart failure status, and if the effect on cardiovascular and heart failure outcomes was influenced by updated mean SBP or by an early change in SBP after drug initiation. empagliflozin 111-124 selenium binding protein 1 Homo sapiens 137-140 32618884-10 2020 The difference in SBP reduction at week 12 between empagliflozin and placebo was 3--5 mmHg and similar regardless of baseline SBP category or HF status at baseline. empagliflozin 51-64 selenium binding protein 1 Homo sapiens 18-21 32618884-12 2020 The treatment effects of empagliflozin on all explored outcomes were independent of updated mean SBP as well of the early drop in SBP on treatment. empagliflozin 25-38 selenium binding protein 1 Homo sapiens 97-100 32511787-8 2020 SBP1 overexpression reduced oxygen consumption in these cells and increased the activation of AMP-activated protein kinase (AMPK), a major regulator of energy homeostasis. Oxygen 28-34 selenium binding protein 1 Homo sapiens 0-4 32511787-10 2020 CONCLUSIONS: Based on the obtained data, it is hypothesized that SBP1 negatively regulates oxidative phosphorylation (OXPHOS) in the healthy prostate cells by the production of H2 O2 and H2 S and consequential activation of AMPK. Hydrogen Peroxide 177-182 selenium binding protein 1 Homo sapiens 65-69 32875989-11 2021 CONCLUSION: The add-on treatment of dapagliflozin and liraglutide had promising clinical outcomes in patients with T2DM and poorly controlled glucose after triple therapy, which include the improvement in blood glucose, insulin resistance, SBP, and renal function. dapagliflozin 36-49 selenium binding protein 1 Homo sapiens 240-243 32511787-10 2020 CONCLUSIONS: Based on the obtained data, it is hypothesized that SBP1 negatively regulates oxidative phosphorylation (OXPHOS) in the healthy prostate cells by the production of H2 O2 and H2 S and consequential activation of AMPK. Deuterium 187-191 selenium binding protein 1 Homo sapiens 65-69 32782308-4 2020 Our previous research indicated that a 35-amino acid region within Dab2, which we refer to as the sulfatide-binding peptide (SBP), contains two potential sulfatide-binding motifs represented by two consecutive polybasic regions. Sulfoglycosphingolipids 98-107 selenium binding protein 1 Homo sapiens 125-128 32782308-5 2020 Using molecular docking, nuclear magnetic resonance, lipid-binding assays, and surface plasmon resonance, this work identifies the critical Dab2 residues within SBP that are responsible for sulfatide binding. Sulfoglycosphingolipids 190-199 selenium binding protein 1 Homo sapiens 161-164 32505063-10 2020 Change in SBP from baseline after 2 h of drug administration was significantly higher with labetalol (p = 0.028 for patients eligible for reperfusion), amlodipine (p = 0.014), and nitroglycerine (p = 0.044). Labetalol 91-100 selenium binding protein 1 Homo sapiens 10-13 32347647-10 2020 Premedication of dexmedetomidine was associated with significant less value of SBP, heart rate, increased incidence of bradycardia, and a lower rate of shivering. Dexmedetomidine 17-32 selenium binding protein 1 Homo sapiens 79-82 32505063-10 2020 Change in SBP from baseline after 2 h of drug administration was significantly higher with labetalol (p = 0.028 for patients eligible for reperfusion), amlodipine (p = 0.014), and nitroglycerine (p = 0.044). Amlodipine 152-162 selenium binding protein 1 Homo sapiens 10-13 32505063-10 2020 Change in SBP from baseline after 2 h of drug administration was significantly higher with labetalol (p = 0.028 for patients eligible for reperfusion), amlodipine (p = 0.014), and nitroglycerine (p = 0.044). Nitroglycerin 180-194 selenium binding protein 1 Homo sapiens 10-13 32505063-11 2020 As for the change in SBP after 24 h, it was significantly higher with labetalol just for patients not eligible for reperfusion (p < 0.001), and amlodipine (p = 0.006). Labetalol 70-79 selenium binding protein 1 Homo sapiens 21-24 32505063-11 2020 As for the change in SBP after 24 h, it was significantly higher with labetalol just for patients not eligible for reperfusion (p < 0.001), and amlodipine (p = 0.006). Amlodipine 144-154 selenium binding protein 1 Homo sapiens 21-24 32738844-10 2020 SBP and DBP goals were achieved by 40.4% and 50.3% of patients on olmesartan monotherapy and by 36.1% and 46.2% of patients on olmesartan+1AHD. olmesartan 66-76 selenium binding protein 1 Homo sapiens 0-3 32738879-8 2020 Compared to baseline, the maximum reduction in BP was observed with combination therapy, N-GITS+LTN + HCT (SBP; - 50.17, p < 0.01, DBP; - 16.55, p < 0.01), followed by N-GITS alone (SBP; - 28.89, p < 0.01, DBP; - 12.21, p < 0.01). n-gits 89-95 selenium binding protein 1 Homo sapiens 107-110 32738879-8 2020 Compared to baseline, the maximum reduction in BP was observed with combination therapy, N-GITS+LTN + HCT (SBP; - 50.17, p < 0.01, DBP; - 16.55, p < 0.01), followed by N-GITS alone (SBP; - 28.89, p < 0.01, DBP; - 12.21, p < 0.01). n-gits 89-95 selenium binding protein 1 Homo sapiens 184-187 32738844-10 2020 SBP and DBP goals were achieved by 40.4% and 50.3% of patients on olmesartan monotherapy and by 36.1% and 46.2% of patients on olmesartan+1AHD. olmesartan 127-137 selenium binding protein 1 Homo sapiens 0-3 32738844-12 2020 SBP and DBP goals were achieved by 38.5% and 49.4% of patients on olmesartan monotherapy and by 31.7% and 42.9% of patients on olmesartan+1AHD. olmesartan 66-76 selenium binding protein 1 Homo sapiens 0-3 32738844-12 2020 SBP and DBP goals were achieved by 38.5% and 49.4% of patients on olmesartan monotherapy and by 31.7% and 42.9% of patients on olmesartan+1AHD. olmesartan 127-137 selenium binding protein 1 Homo sapiens 0-3 32791755-10 2020 CONCLUSIONS: Patients taking the DSM therapy had better effects in reducing the level of HbA1c, FPG, body weight, SBP and DBP than the DM and SM therapy. Samarium 34-36 selenium binding protein 1 Homo sapiens 114-117 32238664-8 2020 In patients with subclinical hypothyroidism, compared with placebo, L-T4 significantly decreased SBP, TSH, T3 and TC and increased FT3 and FT4. Thyroxine 68-72 selenium binding protein 1 Homo sapiens 97-100 32708992-8 2020 Strong associations with SBP were observed for riboflavin (Beta(SE) = -1.49(0.38), P = 1.00 x 10-4) and tryptophan (-0.31(0.01), P = 5 x 10-4), while with DBP for alcohol (0.05(0.07), P = 1.00 x 10-4) and lactose (-0.05(0.0), P = 1.3 x 10-3). Riboflavin 47-57 selenium binding protein 1 Homo sapiens 25-28 32708992-8 2020 Strong associations with SBP were observed for riboflavin (Beta(SE) = -1.49(0.38), P = 1.00 x 10-4) and tryptophan (-0.31(0.01), P = 5 x 10-4), while with DBP for alcohol (0.05(0.07), P = 1.00 x 10-4) and lactose (-0.05(0.0), P = 1.3 x 10-3). Tryptophan 104-114 selenium binding protein 1 Homo sapiens 25-28 32708992-8 2020 Strong associations with SBP were observed for riboflavin (Beta(SE) = -1.49(0.38), P = 1.00 x 10-4) and tryptophan (-0.31(0.01), P = 5 x 10-4), while with DBP for alcohol (0.05(0.07), P = 1.00 x 10-4) and lactose (-0.05(0.0), P = 1.3 x 10-3). Alcohols 163-170 selenium binding protein 1 Homo sapiens 25-28 32708992-8 2020 Strong associations with SBP were observed for riboflavin (Beta(SE) = -1.49(0.38), P = 1.00 x 10-4) and tryptophan (-0.31(0.01), P = 5 x 10-4), while with DBP for alcohol (0.05(0.07), P = 1.00 x 10-4) and lactose (-0.05(0.0), P = 1.3 x 10-3). Lactose 205-212 selenium binding protein 1 Homo sapiens 25-28 32090368-9 2020 CONCLUSIONS: Patients without any CYP2D6 metabolic capacities appear to have increased reduction in DBP, HR, and SBP during metoprolol treatment and may be at a higher risk of bradycardia compared to patients with active CYP2D6 phenotypes. Metoprolol 124-134 selenium binding protein 1 Homo sapiens 113-116 32428313-4 2020 Conversion of 2 - 4 with [ t Bu 2 SbP( t Bu)Li(OEt 2 )] 2 leads to the remarkable interpnictogens [( t BuNAs) 2 ( t BuN) 2 ]PnP( t Bu)Sb t Bu 2 (Pn = As ( 5 ), Sb ( 6 ), Bi ( 7 )), whereby 7 is the first example of a molecule containing all five group 15 elements. Arsenic 106-108 selenium binding protein 1 Homo sapiens 34-37 32320672-3 2020 Each of the three transporters uses a different allosteric network: in the constitutive B12 importer BtuCD, ATP binding is the main driver of allostery and docking/undocking of the substrate-binding protein (SBP) is the driven event. Adenosine Triphosphate 108-111 selenium binding protein 1 Homo sapiens 181-206 32187034-7 2020 RESULTS: The loge NT-proBNP values were significantly correlated with the CV of SBP (r = 0.42), DeltaSBP (r = 0.41), the CV of DBP (r = 0.32), and DeltaDBP (r = 0.28). nt-probnp 18-27 selenium binding protein 1 Homo sapiens 80-83 32187034-9 2020 A multiple linear regression analysis revealed that higher CV of SBP and DeltaSBP were significantly associated with loge NT-proBNP. nt-probnp 122-131 selenium binding protein 1 Homo sapiens 65-68 32636793-6 2020 Conclusion: This is the first randomized trial directly comparing the efficacy of different SBP targets after EVT reperfusion. EVT 110-113 selenium binding protein 1 Homo sapiens 92-95 32636793-7 2020 This prospective trial aims to determine whether a "tight" SBP control after EVT reperfusion can reduce the risk of ICH. EVT 77-80 selenium binding protein 1 Homo sapiens 59-62 32320672-3 2020 Each of the three transporters uses a different allosteric network: in the constitutive B12 importer BtuCD, ATP binding is the main driver of allostery and docking/undocking of the substrate-binding protein (SBP) is the driven event. Adenosine Triphosphate 108-111 selenium binding protein 1 Homo sapiens 208-211 32328303-7 2020 BaPWV independently and gradably predicted the risk of incident hypertension and the SBP level at revisit (odds ratio or beta (95% confidence interval) for participants with baPWV in quartile 4 vs. quartile 1: 2.72 (1.54, 4.78) for incident hypertension and 5.92 (4.26, 7.58) for SBP, P for trend: <0.001) after adjusting demonstrated risk factors. bapwv 0-5 selenium binding protein 1 Homo sapiens 85-88 31147972-1 2020 PURPOSE: To compare the incidences of positive hemodynamic response (HR > 100 beats min-1 or SBP > 160 mmHg) during abdominal exploration and moderate pain after surgery, when using dexmedetomidine infusion and rectus sheath block. Dexmedetomidine 188-203 selenium binding protein 1 Homo sapiens 96-99 32259613-7 2020 The Low-sodium, High-fiber, DASH, Low-fat, Low-protein and Vegan dietary approach were significantly more effective in reducing SBP compared to a control diet. Sodium 8-14 selenium binding protein 1 Homo sapiens 128-131 32259613-9 2020 The Low-sodium and High fiber diets had the greatest lowering effect on SBP and DBP in T2D patients. Sodium 8-14 selenium binding protein 1 Homo sapiens 72-75 32259613-9 2020 The Low-sodium and High fiber diets had the greatest lowering effect on SBP and DBP in T2D patients. Dietary Fiber 24-29 selenium binding protein 1 Homo sapiens 72-75 32259613-11 2020 The High-fiber and Low-sodium diets had the greatest lowering effect on SBP and DBP in T2D. Dietary Fiber 9-14 selenium binding protein 1 Homo sapiens 72-75 32259613-11 2020 The High-fiber and Low-sodium diets had the greatest lowering effect on SBP and DBP in T2D. Sodium 23-29 selenium binding protein 1 Homo sapiens 72-75 32105387-14 2020 In controls, TRPV 1 protein expression was related to the % change in SBP (r = -0.77, p = 0.02) and MAP (r = -0.72, p = 0.03) with FENT (relative to PLA) during exercise. Fentanyl 131-135 selenium binding protein 1 Homo sapiens 70-73 32341999-0 2020 Emergence of Ferrichelatase Activity in a Siderophore-Binding Protein Supports an Iron Shuttle in Bacteria. Iron 82-86 selenium binding protein 1 Homo sapiens 42-69 32341999-2 2020 In Gram-positive bacteria, the currently accepted paradigm in siderophore-mediated iron acquisition is that effluxed metal-free siderophores extract ferric iron from biological sources and the resulting ferric siderophore complex undergoes diffusion-controlled association with a surface-displayed siderophore-binding protein (SBP) followed by ABC permease-mediated translocation across the cell envelope powered by ATP hydrolysis. Iron 83-87 selenium binding protein 1 Homo sapiens 298-325 32341999-2 2020 In Gram-positive bacteria, the currently accepted paradigm in siderophore-mediated iron acquisition is that effluxed metal-free siderophores extract ferric iron from biological sources and the resulting ferric siderophore complex undergoes diffusion-controlled association with a surface-displayed siderophore-binding protein (SBP) followed by ABC permease-mediated translocation across the cell envelope powered by ATP hydrolysis. Iron 83-87 selenium binding protein 1 Homo sapiens 327-330 32341999-2 2020 In Gram-positive bacteria, the currently accepted paradigm in siderophore-mediated iron acquisition is that effluxed metal-free siderophores extract ferric iron from biological sources and the resulting ferric siderophore complex undergoes diffusion-controlled association with a surface-displayed siderophore-binding protein (SBP) followed by ABC permease-mediated translocation across the cell envelope powered by ATP hydrolysis. Metals 117-122 selenium binding protein 1 Homo sapiens 298-325 32341999-2 2020 In Gram-positive bacteria, the currently accepted paradigm in siderophore-mediated iron acquisition is that effluxed metal-free siderophores extract ferric iron from biological sources and the resulting ferric siderophore complex undergoes diffusion-controlled association with a surface-displayed siderophore-binding protein (SBP) followed by ABC permease-mediated translocation across the cell envelope powered by ATP hydrolysis. Metals 117-122 selenium binding protein 1 Homo sapiens 327-330 32341999-2 2020 In Gram-positive bacteria, the currently accepted paradigm in siderophore-mediated iron acquisition is that effluxed metal-free siderophores extract ferric iron from biological sources and the resulting ferric siderophore complex undergoes diffusion-controlled association with a surface-displayed siderophore-binding protein (SBP) followed by ABC permease-mediated translocation across the cell envelope powered by ATP hydrolysis. Adenosine Triphosphate 416-419 selenium binding protein 1 Homo sapiens 298-325 32341999-4 2020 The resulting SBP-bound ferric siderophore complex is ready for import through an associated membrane permease and enzymatic turnover is achieved through cofactor replacement from the readily available pool of extracellular siderophores. Ferric enterobactin ion 24-30 selenium binding protein 1 Homo sapiens 14-17 32341999-5 2020 This new "iron shuttle" model closes a major knowledge gap in microbial iron acquisition and defines new roles of the siderophore and SBP as cofactor and enzyme, respectively, in addition to the classically accepted roles as a transport substrate and receptor pair. Iron 10-14 selenium binding protein 1 Homo sapiens 134-137 32341999-5 2020 This new "iron shuttle" model closes a major knowledge gap in microbial iron acquisition and defines new roles of the siderophore and SBP as cofactor and enzyme, respectively, in addition to the classically accepted roles as a transport substrate and receptor pair. Iron 72-76 selenium binding protein 1 Homo sapiens 134-137 32398634-6 2022 In the TB, mean muscle activity values were significantly (p < 0.001) greater in the stable SwB intervention than the SBp and UBp. Terbium 7-9 selenium binding protein 1 Homo sapiens 118-121 32395338-16 2020 High-density lipoprotein cholesterol was positively associated with SBP (p < 0.005), DBP (p < 0.005), and MAP (p < 0.001) for women and positively associated with SBP, DBP, and MAP (p < 0.001 for all three) and PP (p < 0.05) for men. Cholesterol 25-36 selenium binding protein 1 Homo sapiens 68-71 32395338-16 2020 High-density lipoprotein cholesterol was positively associated with SBP (p < 0.005), DBP (p < 0.005), and MAP (p < 0.001) for women and positively associated with SBP, DBP, and MAP (p < 0.001 for all three) and PP (p < 0.05) for men. Cholesterol 25-36 selenium binding protein 1 Homo sapiens 163-166 32317001-6 2020 A decline in end point ambulatory blood pressure (p = 0.031) and greater mean reduction in office SBP (29.7 +- 13.0 mmHg, p = 0.021) was noted in the propranolol arm. Propranolol 150-161 selenium binding protein 1 Homo sapiens 98-101 32328303-7 2020 BaPWV independently and gradably predicted the risk of incident hypertension and the SBP level at revisit (odds ratio or beta (95% confidence interval) for participants with baPWV in quartile 4 vs. quartile 1: 2.72 (1.54, 4.78) for incident hypertension and 5.92 (4.26, 7.58) for SBP, P for trend: <0.001) after adjusting demonstrated risk factors. bapwv 0-5 selenium binding protein 1 Homo sapiens 280-283 32328303-7 2020 BaPWV independently and gradably predicted the risk of incident hypertension and the SBP level at revisit (odds ratio or beta (95% confidence interval) for participants with baPWV in quartile 4 vs. quartile 1: 2.72 (1.54, 4.78) for incident hypertension and 5.92 (4.26, 7.58) for SBP, P for trend: <0.001) after adjusting demonstrated risk factors. bapwv 174-179 selenium binding protein 1 Homo sapiens 85-88 32328303-8 2020 Besides, the effects of baseline baPWV on either incident hypertension or SBP at revisit were interactively modified by the level of baseline SBP; the effect size increased as the SBP level decreased. bapwv 33-38 selenium binding protein 1 Homo sapiens 74-77 32328303-8 2020 Besides, the effects of baseline baPWV on either incident hypertension or SBP at revisit were interactively modified by the level of baseline SBP; the effect size increased as the SBP level decreased. bapwv 33-38 selenium binding protein 1 Homo sapiens 142-145 32328303-8 2020 Besides, the effects of baseline baPWV on either incident hypertension or SBP at revisit were interactively modified by the level of baseline SBP; the effect size increased as the SBP level decreased. bapwv 33-38 selenium binding protein 1 Homo sapiens 142-145 32328303-9 2020 baPWV independently predicted the risk of hypertension and BP progression, modified by the level of SBP at baseline in this Chinese community-based population. bapwv 0-5 selenium binding protein 1 Homo sapiens 100-103 31834126-7 2020 The causal mediation analysis found that UACR partially mediated the association of baseline uric acid with follow-up SBP (mediate proportion: 9.14%, 95% CI: 1.58-23.00%) and DBP (mediate proportion: 7.38%, 95% CI: 1.05-19.00%). Uric Acid 93-102 selenium binding protein 1 Homo sapiens 118-121 31651093-10 2020 With the best cutoff value of 6.01, elevated NLR was independently associated with the presence of R-DWILs (OR = 3.170, 95% CI 1.306-7.697, P = .011) in the bivariate logistic regression analysis with adjustment for age, sex, atrial fibrillation, previous ischemic stroke/TIA, SBP on admission, hematoma volume, and IVH. r-dwils 99-106 selenium binding protein 1 Homo sapiens 277-280 31950414-4 2020 Associations between natural logarithm-transformed cadmium levels and BP (systolic (SBP) and diastolic blood pressure (DBP)) were performed by adjusted linear regression models. Cadmium 51-58 selenium binding protein 1 Homo sapiens 84-87 32264876-12 2020 The multiple linear regression showed that the SBP was highly associated with the TC (p < 0.001; beta = 0.464). Technetium 82-84 selenium binding protein 1 Homo sapiens 47-50 31833949-4 2020 For the ANSI/AAMI/ISO protocol, the average device-observer difference for SBP/DBP was 0.4 +- 7/-1.5 +- 7 mmHg fulfilling the two criteria of the protocol. Isoproterenol 18-21 selenium binding protein 1 Homo sapiens 75-78 31693535-5 2020 RESULTS: Nebivolol significantly decreased mean SBP and DBP at 12 and 24 weeks compared with baseline (P < 0.0001). Nebivolol 9-18 selenium binding protein 1 Homo sapiens 48-51 32152170-10 2020 METHODS AND ANALYSIS: This is a single-site, double-blind, parallel-group, randomised, placebo-controlled pilot study of 10 participants comparing 98% CBD oil with placebo in reducing SBP in children aged 8-16 years with ID. cbd oil 151-158 selenium binding protein 1 Homo sapiens 184-187 31915906-6 2020 RESULTS: 4-HIIT and MCT showed positive outcomes for almost all variables while 1-HIIT had a positive influence only on SBP and SD2 index. 1-hiit 80-86 selenium binding protein 1 Homo sapiens 120-123 32184402-6 2020 GSH levels correlated negatively with SBP, DBP and MBP values in all participants (p = 0.0010; p = 0.0350 and p = 0.0050) as well as with MBP values in high normal and grade 1 hypertension (p = 0.0290). Glutathione 0-3 selenium binding protein 1 Homo sapiens 38-41 32184402-7 2020 The levels of GSSG correlated positively with SBP, DBP and MBP values in all participants (p = 0.0410; p = 0.0330 and, p = 0.0220). Glutathione Disulfide 14-18 selenium binding protein 1 Homo sapiens 46-49 33402920-6 2020 The relation of plasma hcy to hypertension was statistically significant for SBP; OR: 1.08 (95% CI, 1.05-1.11) and DBP; OR: 1.08 (95% CI, 1.03-1.13) in the unadjusted model. Homocysteine 23-26 selenium binding protein 1 Homo sapiens 77-80 31748705-9 2020 Patients whose UA level increased more than 1 mg/dl showed significantly higher baseline office SBP and plasma glucose and showed greater decline in renal function compared with those who showed less UA increase (<1 mg/dl). Uric Acid 15-17 selenium binding protein 1 Homo sapiens 96-99 31693535-7 2020 The reductions of SBP and DBP were notably greater when nebivolol was used as monotherapy in de novo patients (P < 0.0001) and as add-on therapy to existing antihypertensives (angiotensin II receptor blockers, angiotensin-converting enzyme inhibitors and calcium channel blockers; P < 0.0001). Nebivolol 56-65 selenium binding protein 1 Homo sapiens 18-21 31693535-7 2020 The reductions of SBP and DBP were notably greater when nebivolol was used as monotherapy in de novo patients (P < 0.0001) and as add-on therapy to existing antihypertensives (angiotensin II receptor blockers, angiotensin-converting enzyme inhibitors and calcium channel blockers; P < 0.0001). Calcium 255-262 selenium binding protein 1 Homo sapiens 18-21 32019489-8 2020 Moreover, rs17782313 and both indices (HEI and DQI-I) had significant interaction on serum glucose concentrations, systolic and diastolic blood pressure (SBP, DBP) in males (P Interaction < 0.05); when adherence to these indices was low, the obesity risk allele was associated with serum glucose concentrations, SBP and DBP. Glucose 91-98 selenium binding protein 1 Homo sapiens 312-315 32019489-8 2020 Moreover, rs17782313 and both indices (HEI and DQI-I) had significant interaction on serum glucose concentrations, systolic and diastolic blood pressure (SBP, DBP) in males (P Interaction < 0.05); when adherence to these indices was low, the obesity risk allele was associated with serum glucose concentrations, SBP and DBP. Glucose 288-295 selenium binding protein 1 Homo sapiens 154-157 31544267-7 2020 Compared with placebo, lorcaserin not only reduced weight, BMI and waist circumference but also improved SBP, DBP, heart rate, LDL, triglycerides, fasting plasma glucose and HbA1c. lorcaserin 23-33 selenium binding protein 1 Homo sapiens 105-108 31633519-6 2020 For Mobil-O-Graph pulse pressure less than 43 mm Hg, the DBP difference was 6.3 +- 5.5, and for Mobil-O-Graph pulse pressure more than 50 mm Hg, the SBP difference was 7.4 +- 9.3. Superoxides 96-109 selenium binding protein 1 Homo sapiens 149-152 30795691-7 2020 Serum total methylarginine load was positively correlated with night-time SBP (r = 0.214, P= 0.029). Methylarginine 12-26 selenium binding protein 1 Homo sapiens 74-77 32064281-11 2020 Conclusion: LV myocardial FDG uptake was higher in subjects with elevated blood pressure and correlated positively with SBP and in particular DBP and MABP. 4-fluoro-4-deoxyglucose 26-29 selenium binding protein 1 Homo sapiens 120-123 31435005-10 2020 For example, added phosphorus (but not plant or animal) was associated with increases in SBP and DBP, 1.24 mmHg/100 mg (0.36, 2.12) and 0.83 mmHg/100 mg (0.22, 1.44), respectively, crude. Phosphorus 19-29 selenium binding protein 1 Homo sapiens 89-92 32080138-3 2020 OBJECTIVES: To analyze the effect of vitamin C (VitC) supplementation on systolic (SBP) and diastolic (DBP) blood pressure in patients with essential hypertension. Ascorbic Acid 37-46 selenium binding protein 1 Homo sapiens 83-86 32080138-3 2020 OBJECTIVES: To analyze the effect of vitamin C (VitC) supplementation on systolic (SBP) and diastolic (DBP) blood pressure in patients with essential hypertension. Ascorbic Acid 48-52 selenium binding protein 1 Homo sapiens 83-86 32080138-13 2020 For an intervention dose of VitC >=500 mg daily, SBP was statistically significant (WMD = -5.01; 95% CI -8.55, -1.48; P = .005). Ascorbic Acid 28-32 selenium binding protein 1 Homo sapiens 49-52 32598663-11 2020 BPTM group characterized by larger decrease in SBP level compared with controls (-16.8+-2.9 mm Hg versus -7.9+-3.9 mm Hg; p. bptm 0-4 selenium binding protein 1 Homo sapiens 47-50 31327485-8 2020 High-dose NTG may be appropriate in H-AHF patients presenting with severe respiratory distress and SBP >=160 mmHg or MAP >=120 mmHg. Nitroglycerin 10-13 selenium binding protein 1 Homo sapiens 99-102 31639655-10 2020 Indirect associations were significant for O3 for SBP among women and men and for DBP among men. Superoxides 43-45 selenium binding protein 1 Homo sapiens 50-53 31672364-11 2020 Ambient PM1 and NO2 mediated 33.0% and 10.9% of the association between greenness and SBP, respectively. Aligeron 16-19 selenium binding protein 1 Homo sapiens 86-89 31895792-6 2020 The median percentage of time spent at targeted SBP goal was 76.2% during the administration of nicardipine and 93.4% during the administration of clevidipine (P = .123).Our study suggests that clevidipine could be an alternative effective drug with an acceptable benefit/risk ratio in the neurosurgical population that fails to achieve BP control with nicardipine treatment. Nicardipine 96-107 selenium binding protein 1 Homo sapiens 48-51 31534190-6 2020 The mean (+-standard deviation: SD) differences in systolic BP (SBP) and diastolic BP (DBP) between the methods were -0.7 +- 7.1 and -1.1 +- 4.5 mmHg, respectively, and those for each participant were -0.7 +- 5.8 mmHg for SBP and -1.1 +- 4.1 mmHg for DBP; the device therefore fulfilled the requirements of the ISO protocol. Diosmin 87-90 selenium binding protein 1 Homo sapiens 51-85 31895792-6 2020 The median percentage of time spent at targeted SBP goal was 76.2% during the administration of nicardipine and 93.4% during the administration of clevidipine (P = .123).Our study suggests that clevidipine could be an alternative effective drug with an acceptable benefit/risk ratio in the neurosurgical population that fails to achieve BP control with nicardipine treatment. clevidipine 147-158 selenium binding protein 1 Homo sapiens 48-51 31895792-6 2020 The median percentage of time spent at targeted SBP goal was 76.2% during the administration of nicardipine and 93.4% during the administration of clevidipine (P = .123).Our study suggests that clevidipine could be an alternative effective drug with an acceptable benefit/risk ratio in the neurosurgical population that fails to achieve BP control with nicardipine treatment. clevidipine 194-205 selenium binding protein 1 Homo sapiens 48-51 31451203-6 2020 In patients received spironolactone, SBP decreased 23+-9mmHg and in furosemide group decreased 16+-3mmHg, P<.01. Spironolactone 21-35 selenium binding protein 1 Homo sapiens 37-40 31557719-0 2020 A Caenorhabditis elegans ortholog of human selenium-binding protein 1 is a pro-aging factor protecting against selenite toxicity. Selenious Acid 111-119 selenium binding protein 1 Homo sapiens 43-69 31557719-1 2020 Human selenium-binding protein 1 (SELENBP1) was originally identified as a protein binding selenium, most likely as selenite. Selenium 6-14 selenium binding protein 1 Homo sapiens 34-42 31861313-1 2019 Linker-protein G (LPG) is a bifunctional fusion protein composed of a solid-binding peptide (SBP, referred as the "linker") with high affinity to silica-based compounds and a Streptococcus protein G (PG), which binds antibodies. Silicon Dioxide 146-152 selenium binding protein 1 Homo sapiens 93-96 31557719-1 2020 Human selenium-binding protein 1 (SELENBP1) was originally identified as a protein binding selenium, most likely as selenite. Selenious Acid 116-124 selenium binding protein 1 Homo sapiens 6-32 31557719-1 2020 Human selenium-binding protein 1 (SELENBP1) was originally identified as a protein binding selenium, most likely as selenite. Selenious Acid 116-124 selenium binding protein 1 Homo sapiens 34-42 31557719-2 2020 SELENBP1 is associated with cellular redox and thiol homeostasis in several respects, including its established role as a methanethiol oxidase that is involved in degradation of methanethiol, a methionine catabolite, generating hydrogen sulfide (H2S) and hydrogen peroxide (H2O2). Sulfhydryl Compounds 47-52 selenium binding protein 1 Homo sapiens 0-8 31557719-2 2020 SELENBP1 is associated with cellular redox and thiol homeostasis in several respects, including its established role as a methanethiol oxidase that is involved in degradation of methanethiol, a methionine catabolite, generating hydrogen sulfide (H2S) and hydrogen peroxide (H2O2). methylmercaptan 122-134 selenium binding protein 1 Homo sapiens 0-8 31557719-2 2020 SELENBP1 is associated with cellular redox and thiol homeostasis in several respects, including its established role as a methanethiol oxidase that is involved in degradation of methanethiol, a methionine catabolite, generating hydrogen sulfide (H2S) and hydrogen peroxide (H2O2). methylmercaptan 178-190 selenium binding protein 1 Homo sapiens 0-8 31557719-2 2020 SELENBP1 is associated with cellular redox and thiol homeostasis in several respects, including its established role as a methanethiol oxidase that is involved in degradation of methanethiol, a methionine catabolite, generating hydrogen sulfide (H2S) and hydrogen peroxide (H2O2). Methionine 194-204 selenium binding protein 1 Homo sapiens 0-8 31557719-2 2020 SELENBP1 is associated with cellular redox and thiol homeostasis in several respects, including its established role as a methanethiol oxidase that is involved in degradation of methanethiol, a methionine catabolite, generating hydrogen sulfide (H2S) and hydrogen peroxide (H2O2). Hydrogen Sulfide 228-244 selenium binding protein 1 Homo sapiens 0-8 31557719-2 2020 SELENBP1 is associated with cellular redox and thiol homeostasis in several respects, including its established role as a methanethiol oxidase that is involved in degradation of methanethiol, a methionine catabolite, generating hydrogen sulfide (H2S) and hydrogen peroxide (H2O2). hydrogen sulfite 246-249 selenium binding protein 1 Homo sapiens 0-8 31557719-2 2020 SELENBP1 is associated with cellular redox and thiol homeostasis in several respects, including its established role as a methanethiol oxidase that is involved in degradation of methanethiol, a methionine catabolite, generating hydrogen sulfide (H2S) and hydrogen peroxide (H2O2). Hydrogen Peroxide 255-272 selenium binding protein 1 Homo sapiens 0-8 31557719-2 2020 SELENBP1 is associated with cellular redox and thiol homeostasis in several respects, including its established role as a methanethiol oxidase that is involved in degradation of methanethiol, a methionine catabolite, generating hydrogen sulfide (H2S) and hydrogen peroxide (H2O2). Water 274-278 selenium binding protein 1 Homo sapiens 0-8 31557719-3 2020 As both H2S and reactive oxygen species (such as H2O2) are major regulators of Caenorhabditis elegans lifespan and stress resistance, we hypothesized that a SELENBP1 ortholog in C. elegans would likely be involved in regulating these aspects. hydrogen sulfite 8-11 selenium binding protein 1 Homo sapiens 157-165 31557719-3 2020 As both H2S and reactive oxygen species (such as H2O2) are major regulators of Caenorhabditis elegans lifespan and stress resistance, we hypothesized that a SELENBP1 ortholog in C. elegans would likely be involved in regulating these aspects. Oxygen 25-31 selenium binding protein 1 Homo sapiens 157-165 31557719-3 2020 As both H2S and reactive oxygen species (such as H2O2) are major regulators of Caenorhabditis elegans lifespan and stress resistance, we hypothesized that a SELENBP1 ortholog in C. elegans would likely be involved in regulating these aspects. Water 49-53 selenium binding protein 1 Homo sapiens 157-165 31557719-9 2020 In summary, Y37A1B.5 is an ortholog of SELENBP1 that shortens C. elegans lifespan and lowers resistance against oxidative stress, while allowing for a better survival under toxic selenite concentrations. Selenious Acid 179-187 selenium binding protein 1 Homo sapiens 39-47 31520830-7 2019 RESULTS: Every doubling of UAs at A3 and maternal UAs at A1 was positively associated with a difference of 0.7-mmHg (95% confidence interval [CI]: 0.1, 1.3) and a 0.7-mmHg (95% CI: 0.05, 1.4) in SBP, respectively. Phenindione 27-30 selenium binding protein 1 Homo sapiens 195-198 30935897-13 2019 CONCLUSION: When given in a manually adjusted infusion, norepinephrine effectively maintained maternal SBP during caesarean delivery under spinal anaesthesia with lower number of physician interventions, and likely less incidence of reactive hypertension and bradycardia compared to phenylephrine. Norepinephrine 56-70 selenium binding protein 1 Homo sapiens 103-106 31343543-9 2019 After 1 month, superior ambulatory central SBP reductions were observed in the perindopril/indapamide/amlodipine (n = 101) vs. Per/Ind group (n = 109) for 24-h/daytime/night-time periods (-4.5 mmHg, P = 0.002/-5.0, P < 0001/-4.1 mmHg, P = 0.016, respectively). Perindopril 79-90 selenium binding protein 1 Homo sapiens 43-46 31343543-9 2019 After 1 month, superior ambulatory central SBP reductions were observed in the perindopril/indapamide/amlodipine (n = 101) vs. Per/Ind group (n = 109) for 24-h/daytime/night-time periods (-4.5 mmHg, P = 0.002/-5.0, P < 0001/-4.1 mmHg, P = 0.016, respectively). Indapamide 91-101 selenium binding protein 1 Homo sapiens 43-46 31343543-9 2019 After 1 month, superior ambulatory central SBP reductions were observed in the perindopril/indapamide/amlodipine (n = 101) vs. Per/Ind group (n = 109) for 24-h/daytime/night-time periods (-4.5 mmHg, P = 0.002/-5.0, P < 0001/-4.1 mmHg, P = 0.016, respectively). Amlodipine 102-112 selenium binding protein 1 Homo sapiens 43-46 31373922-1 2019 OBJECTIVES: The aim of this study was to identify associations between the smoothness index of central SBP (CSBP) and changes of ambulatory carotid femoral pulse wave velocity in response to 20-week treatments with losartan and amlodipine vs. losartan and hydrochlorthiazide combinations. Losartan 215-223 selenium binding protein 1 Homo sapiens 103-106 31373922-1 2019 OBJECTIVES: The aim of this study was to identify associations between the smoothness index of central SBP (CSBP) and changes of ambulatory carotid femoral pulse wave velocity in response to 20-week treatments with losartan and amlodipine vs. losartan and hydrochlorthiazide combinations. Amlodipine 228-238 selenium binding protein 1 Homo sapiens 103-106 31373922-1 2019 OBJECTIVES: The aim of this study was to identify associations between the smoothness index of central SBP (CSBP) and changes of ambulatory carotid femoral pulse wave velocity in response to 20-week treatments with losartan and amlodipine vs. losartan and hydrochlorthiazide combinations. Losartan 243-251 selenium binding protein 1 Homo sapiens 103-106 31373922-1 2019 OBJECTIVES: The aim of this study was to identify associations between the smoothness index of central SBP (CSBP) and changes of ambulatory carotid femoral pulse wave velocity in response to 20-week treatments with losartan and amlodipine vs. losartan and hydrochlorthiazide combinations. Hydrochlorothiazide 256-274 selenium binding protein 1 Homo sapiens 103-106 31685792-7 2019 RESULTS: In the dapagliflozin group, triglyceride (TG), systolic pressure (SBP) and diastolic pressure (DBP) significantly decreased following treatment, while high-density lipoprotein cholesterol (HDL-C) significantly increased (P < 0.05). dapagliflozin 16-29 selenium binding protein 1 Homo sapiens 75-78 31520830-7 2019 RESULTS: Every doubling of UAs at A3 and maternal UAs at A1 was positively associated with a difference of 0.7-mmHg (95% confidence interval [CI]: 0.1, 1.3) and a 0.7-mmHg (95% CI: 0.05, 1.4) in SBP, respectively. Phenindione 50-53 selenium binding protein 1 Homo sapiens 195-198 31520830-10 2019 The Weighted Quantile Sum (WQS) regression confirmed that adolescents" UAs at A3 and maternal UAs at A1 contributed the most to the overall effect of As exposure at three life stages on SBP. Phenindione 94-97 selenium binding protein 1 Homo sapiens 186-189 31520830-11 2019 Mixture analyses using Bayesian Kernel Machine Regression identified UAs at A3 as a significant contributor to SBP and DBP independent of other concurrent blood levels of cadmium, lead, manganese, and selenium. Phenindione 69-72 selenium binding protein 1 Homo sapiens 111-114 31686456-6 2019 In multivariate analyses, oxygen desaturation index and JAG1 genotype independently predicted morning SBP (P=0.001, P=0.003, respectively) and DBP (P<0.001, P=0.005, respectively), and evening SBP (P=0.019, P=0.048, respectively) and DBP (P=0.018, P=0.018, respectively). Oxygen 26-32 selenium binding protein 1 Homo sapiens 102-105 30631130-7 2019 Aliskiren induced slightly greater DBP and SBP reductions than other antihypertensive agents (WMD -0.77 mmHg, 95% CI [-2.01;0.46 mmHg] and WMD -1.14 mmHg, 95% CI [-2.78;0.50 mmHg], respectively). aliskiren 0-9 selenium binding protein 1 Homo sapiens 43-46 31736865-7 2019 DCI patients showed a more pronounced rise in MAP and DBP over the examined time period as well as a higher decrease in SBP following Nimodipine administration. Nimodipine 134-144 selenium binding protein 1 Homo sapiens 120-123 31736865-8 2019 A fall of 18 mmHg in SBP after Nimodipine administration showed a sensitivity of 82.4% and specificity of 92.3% for occurrence of DCI. Nimodipine 31-41 selenium binding protein 1 Homo sapiens 21-24 31601788-2 2019 Supplementation of biotin competitively disrupts the interaction between the SBP moiety and streptavidin, liberating the chimeric target protein from its hooks, while addition of avidin causes the removal of biotin from the system and reestablishes the interaction. Biotin 19-25 selenium binding protein 1 Homo sapiens 77-80 31601788-2 2019 Supplementation of biotin competitively disrupts the interaction between the SBP moiety and streptavidin, liberating the chimeric target protein from its hooks, while addition of avidin causes the removal of biotin from the system and reestablishes the interaction. Biotin 208-214 selenium binding protein 1 Homo sapiens 77-80