PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
32996649-12	2020	Furthermore, increased N-glycosylation of CREBH, as achieved by overexpressing GnT-V could significantly improve liver lesion caused by unglycosylation of CREBH.	Nitrogen	23-24	mannoside acetylglucosaminyltransferase 5	Mus musculus	79-84
33223850-0	2020	miR-124-3p Regulates FGF2-EGFR Pathway to Overcome Pemetrexed Resistance in Lung Adenocarcinoma Cells by Targeting MGAT5.	Pemetrexed	51-61	mannoside acetylglucosaminyltransferase 5	Mus musculus	115-120
33223850-1	2020	Objective: To investigate whether miR-124-3p regulates the fibroblast growth factor 2 (FGF2)-epidermal growth factor receptor (EGFR) pathway by targeting MGAT5 to affect the pemetrexed resistance in lung adenocarcinoma cells.	Pemetrexed	174-184	mannoside acetylglucosaminyltransferase 5	Mus musculus	154-159
33223850-11	2020	Conclusion: miR-124-3p may inhibit the FGF2-EGFR pathway by targeting MGAT5 to decrease pemetrexed resistance in lung adenocarcinoma cells.	Pemetrexed	88-98	mannoside acetylglucosaminyltransferase 5	Mus musculus	70-75
26349931-2	2016	N-Acetylglucosaminyltransferase V (GnT-V) is involved in the biosynthesis of N-acetylglucosamine (GlcNAc) by beta1,6-branching on N-glycans and is induced in various pathologic processes, such as inflammation and regeneration.	Acetylglucosamine	77-96	mannoside acetylglucosaminyltransferase 5	Mus musculus	0-33
27329152-2	2016	Mgat5 is an N-acetylglucosaminyltransferase in the Golgi pathway that remodels the N-glycans of glycoproteins at the cell surface.	n-glycans	83-92	mannoside acetylglucosaminyltransferase 5	Mus musculus	0-5
27329152-6	2016	We found an interaction between Mgat5 genotype and maternal rearing condition in which Mgat5(-/-) mice subjected to early life stress had lower glucose levels and higher bone density.	Glucose	144-151	mannoside acetylglucosaminyltransferase 5	Mus musculus	32-37
27329152-6	2016	We found an interaction between Mgat5 genotype and maternal rearing condition in which Mgat5(-/-) mice subjected to early life stress had lower glucose levels and higher bone density.	Glucose	144-151	mannoside acetylglucosaminyltransferase 5	Mus musculus	87-92
27329152-7	2016	Mgat5(-/-) genotype was also associated with less immobility in the forced swim test and greater sucrose consumption, consistent with a less depression-like phenotype.	Sucrose	97-104	mannoside acetylglucosaminyltransferase 5	Mus musculus	0-5
32161138-4	2020	This spontaneous autoimmune phenotype was recapitulated in mice lacking beta1,6N-acetylglucosaminyltransferase V (Mgat5), an enzyme responsible for generating beta1,6-branched complex N-glycans, which serve as a major ligand for this lectin.	,6-branched complex	164-183	mannoside acetylglucosaminyltransferase 5	Mus musculus	72-112
32161138-4	2020	This spontaneous autoimmune phenotype was recapitulated in mice lacking beta1,6N-acetylglucosaminyltransferase V (Mgat5), an enzyme responsible for generating beta1,6-branched complex N-glycans, which serve as a major ligand for this lectin.	,6-branched complex	164-183	mannoside acetylglucosaminyltransferase 5	Mus musculus	114-119
32161138-4	2020	This spontaneous autoimmune phenotype was recapitulated in mice lacking beta1,6N-acetylglucosaminyltransferase V (Mgat5), an enzyme responsible for generating beta1,6-branched complex N-glycans, which serve as a major ligand for this lectin.	n-glycans	184-193	mannoside acetylglucosaminyltransferase 5	Mus musculus	72-112
32161138-4	2020	This spontaneous autoimmune phenotype was recapitulated in mice lacking beta1,6N-acetylglucosaminyltransferase V (Mgat5), an enzyme responsible for generating beta1,6-branched complex N-glycans, which serve as a major ligand for this lectin.	n-glycans	184-193	mannoside acetylglucosaminyltransferase 5	Mus musculus	114-119
27533452-5	2016	Accordingly, overexpression of MGAT5-mediated branched N-glycans both in gastric cancer cells and transgenic mice models led to a significant decrease of O-mannosyl glycans attached to E-cadherin that was associated with impairment of its tumour suppressive functions.	branched n-glycans	46-64	mannoside acetylglucosaminyltransferase 5	Mus musculus	31-36
27533452-5	2016	Accordingly, overexpression of MGAT5-mediated branched N-glycans both in gastric cancer cells and transgenic mice models led to a significant decrease of O-mannosyl glycans attached to E-cadherin that was associated with impairment of its tumour suppressive functions.	o-mannosyl glycans	154-172	mannoside acetylglucosaminyltransferase 5	Mus musculus	31-36
26349931-13	2016	Clodronate liposome treatment to deplete macrophages blocked the exacerbation of DSS-induced colitis and impairment of interleukin-10 production in GnT-V transgenic mice.	Clodronic Acid	0-10	mannoside acetylglucosaminyltransferase 5	Mus musculus	148-153
26349931-2	2016	N-Acetylglucosaminyltransferase V (GnT-V) is involved in the biosynthesis of N-acetylglucosamine (GlcNAc) by beta1,6-branching on N-glycans and is induced in various pathologic processes, such as inflammation and regeneration.	Acetylglucosamine	77-96	mannoside acetylglucosaminyltransferase 5	Mus musculus	35-40
26349931-2	2016	N-Acetylglucosaminyltransferase V (GnT-V) is involved in the biosynthesis of N-acetylglucosamine (GlcNAc) by beta1,6-branching on N-glycans and is induced in various pathologic processes, such as inflammation and regeneration.	Acetylglucosamine	98-104	mannoside acetylglucosaminyltransferase 5	Mus musculus	0-33
26349931-2	2016	N-Acetylglucosaminyltransferase V (GnT-V) is involved in the biosynthesis of N-acetylglucosamine (GlcNAc) by beta1,6-branching on N-glycans and is induced in various pathologic processes, such as inflammation and regeneration.	Acetylglucosamine	98-104	mannoside acetylglucosaminyltransferase 5	Mus musculus	35-40
26349931-2	2016	N-Acetylglucosaminyltransferase V (GnT-V) is involved in the biosynthesis of N-acetylglucosamine (GlcNAc) by beta1,6-branching on N-glycans and is induced in various pathologic processes, such as inflammation and regeneration.	n-glycans	130-139	mannoside acetylglucosaminyltransferase 5	Mus musculus	0-33
26349931-2	2016	N-Acetylglucosaminyltransferase V (GnT-V) is involved in the biosynthesis of N-acetylglucosamine (GlcNAc) by beta1,6-branching on N-glycans and is induced in various pathologic processes, such as inflammation and regeneration.	n-glycans	130-139	mannoside acetylglucosaminyltransferase 5	Mus musculus	35-40
26349931-11	2016	RESULTS: DSS-induced colitis and colitis induced by trinitrobenzene sulfonic acid were markedly exacerbated in GnT-V transgenic mice compared with wild-type mice.	dss	9-12	mannoside acetylglucosaminyltransferase 5	Mus musculus	111-116
26349931-11	2016	RESULTS: DSS-induced colitis and colitis induced by trinitrobenzene sulfonic acid were markedly exacerbated in GnT-V transgenic mice compared with wild-type mice.	Trinitrobenzenesulfonic Acid	52-81	mannoside acetylglucosaminyltransferase 5	Mus musculus	111-116
25876794-0	2015	Oligosaccharide modification by N-acetylglucosaminyltransferase-V in macrophages are involved in pathogenesis of bleomycin-induced scleroderma.	Oligosaccharides	0-15	mannoside acetylglucosaminyltransferase 5	Mus musculus	32-65
26041473-0	2016	Ectopic expression of N-acetylglucosaminyltransferase V accelerates hepatic triglyceride synthesis.	Triglycerides	76-88	mannoside acetylglucosaminyltransferase 5	Mus musculus	22-55
26041473-5	2016	In this study, we investigated the effects of aberrant glycosylation by GnT-V on hepatic triglyceride production.	Triglycerides	89-101	mannoside acetylglucosaminyltransferase 5	Mus musculus	72-77
26041473-13	2016	CONCLUSION: Our study demonstrates that enhancement of hepatic GnT-V activity accelerates triglyceride synthesis and VLDL secretion.	Triglycerides	90-102	mannoside acetylglucosaminyltransferase 5	Mus musculus	63-68
25876794-0	2015	Oligosaccharide modification by N-acetylglucosaminyltransferase-V in macrophages are involved in pathogenesis of bleomycin-induced scleroderma.	Bleomycin	113-122	mannoside acetylglucosaminyltransferase 5	Mus musculus	32-65
25876794-1	2015	Oligosaccharide modification by N-acetylglucosaminyltransferase-V (GnT-V), which catalyses the formation of beta1,6 GlcNAc (N-acetylglucosamine) branches on N-glycans, is associated with various pathologies, such as cancer metastasis, multiple sclerosis and liver fibrosis.	Oligosaccharides	0-15	mannoside acetylglucosaminyltransferase 5	Mus musculus	32-65
25876794-1	2015	Oligosaccharide modification by N-acetylglucosaminyltransferase-V (GnT-V), which catalyses the formation of beta1,6 GlcNAc (N-acetylglucosamine) branches on N-glycans, is associated with various pathologies, such as cancer metastasis, multiple sclerosis and liver fibrosis.	Oligosaccharides	0-15	mannoside acetylglucosaminyltransferase 5	Mus musculus	67-72
25876794-1	2015	Oligosaccharide modification by N-acetylglucosaminyltransferase-V (GnT-V), which catalyses the formation of beta1,6 GlcNAc (N-acetylglucosamine) branches on N-glycans, is associated with various pathologies, such as cancer metastasis, multiple sclerosis and liver fibrosis.	beta1,6 glcnac	108-122	mannoside acetylglucosaminyltransferase 5	Mus musculus	32-65
25876794-1	2015	Oligosaccharide modification by N-acetylglucosaminyltransferase-V (GnT-V), which catalyses the formation of beta1,6 GlcNAc (N-acetylglucosamine) branches on N-glycans, is associated with various pathologies, such as cancer metastasis, multiple sclerosis and liver fibrosis.	beta1,6 glcnac	108-122	mannoside acetylglucosaminyltransferase 5	Mus musculus	67-72
25876794-1	2015	Oligosaccharide modification by N-acetylglucosaminyltransferase-V (GnT-V), which catalyses the formation of beta1,6 GlcNAc (N-acetylglucosamine) branches on N-glycans, is associated with various pathologies, such as cancer metastasis, multiple sclerosis and liver fibrosis.	Acetylglucosamine	124-143	mannoside acetylglucosaminyltransferase 5	Mus musculus	32-65
25876794-1	2015	Oligosaccharide modification by N-acetylglucosaminyltransferase-V (GnT-V), which catalyses the formation of beta1,6 GlcNAc (N-acetylglucosamine) branches on N-glycans, is associated with various pathologies, such as cancer metastasis, multiple sclerosis and liver fibrosis.	Acetylglucosamine	124-143	mannoside acetylglucosaminyltransferase 5	Mus musculus	67-72
25876794-1	2015	Oligosaccharide modification by N-acetylglucosaminyltransferase-V (GnT-V), which catalyses the formation of beta1,6 GlcNAc (N-acetylglucosamine) branches on N-glycans, is associated with various pathologies, such as cancer metastasis, multiple sclerosis and liver fibrosis.	n-glycans	157-166	mannoside acetylglucosaminyltransferase 5	Mus musculus	32-65
25876794-1	2015	Oligosaccharide modification by N-acetylglucosaminyltransferase-V (GnT-V), which catalyses the formation of beta1,6 GlcNAc (N-acetylglucosamine) branches on N-glycans, is associated with various pathologies, such as cancer metastasis, multiple sclerosis and liver fibrosis.	n-glycans	157-166	mannoside acetylglucosaminyltransferase 5	Mus musculus	67-72
25876794-6	2015	Expression of GnT-V was also elevated in bleomycin (BLM)-injected sclerotic skin, and MGAT5(-/-) mice were resistant to BLM-induced skin sclerosis with reduced collagen type 1 alpha1 content, suggesting the biological significance of GnT-V in skin sclerosis.	Bleomycin	41-50	mannoside acetylglucosaminyltransferase 5	Mus musculus	14-19
25876794-6	2015	Expression of GnT-V was also elevated in bleomycin (BLM)-injected sclerotic skin, and MGAT5(-/-) mice were resistant to BLM-induced skin sclerosis with reduced collagen type 1 alpha1 content, suggesting the biological significance of GnT-V in skin sclerosis.	Bleomycin	52-55	mannoside acetylglucosaminyltransferase 5	Mus musculus	14-19
25572342-1	2015	N-Acetylglucosaminyltransferase V (GnT-V) catalyzes beta1-6 branching in asparagine-linked oligosaccharides and is one of the most important glycosyltransferases involved in carcinogenesis, cancer metastasis and immunity.	asparagine-linked oligosaccharides	73-107	mannoside acetylglucosaminyltransferase 5	Mus musculus	0-33
25572342-1	2015	N-Acetylglucosaminyltransferase V (GnT-V) catalyzes beta1-6 branching in asparagine-linked oligosaccharides and is one of the most important glycosyltransferases involved in carcinogenesis, cancer metastasis and immunity.	asparagine-linked oligosaccharides	73-107	mannoside acetylglucosaminyltransferase 5	Mus musculus	35-40
25274627-1	2014	Deletion of GnT-V (MGAT5), which synthesizes N-glycans with beta(1,6)-branched glycans, reduced the compartment of cancer stem cells (CSC) in the her-2 mouse model of breast cancer, leading to delay of tumor onset.	n-glycans	45-54	mannoside acetylglucosaminyltransferase 5	Mus musculus	19-24
25524127-2	2015	However, the expression profiles and roles of N-acetylglucosaminyltransferase-V (GnT-V), an enzyme that forms beta1,6-branched N-glycans, in NPCs remain unknown.	beta1,6-branched n-glycans	110-136	mannoside acetylglucosaminyltransferase 5	Mus musculus	46-79
25524127-2	2015	However, the expression profiles and roles of N-acetylglucosaminyltransferase-V (GnT-V), an enzyme that forms beta1,6-branched N-glycans, in NPCs remain unknown.	beta1,6-branched n-glycans	110-136	mannoside acetylglucosaminyltransferase 5	Mus musculus	81-86
25274627-1	2014	Deletion of GnT-V (MGAT5), which synthesizes N-glycans with beta(1,6)-branched glycans, reduced the compartment of cancer stem cells (CSC) in the her-2 mouse model of breast cancer, leading to delay of tumor onset.	n-glycans	45-54	mannoside acetylglucosaminyltransferase 5	Mus musculus	12-17
25274627-1	2014	Deletion of GnT-V (MGAT5), which synthesizes N-glycans with beta(1,6)-branched glycans, reduced the compartment of cancer stem cells (CSC) in the her-2 mouse model of breast cancer, leading to delay of tumor onset.	beta(1,6)-branched glycans	60-86	mannoside acetylglucosaminyltransferase 5	Mus musculus	12-17
25274627-1	2014	Deletion of GnT-V (MGAT5), which synthesizes N-glycans with beta(1,6)-branched glycans, reduced the compartment of cancer stem cells (CSC) in the her-2 mouse model of breast cancer, leading to delay of tumor onset.	beta(1,6)-branched glycans	60-86	mannoside acetylglucosaminyltransferase 5	Mus musculus	19-24
23960081-1	2013	Our previous studies on a beta1,6-N-acetylglucosaminyltransferase, GnT-IX (GnT-Vb), a homolog of GnT-V, indicated that the enzyme has a broad GlcNAc transfer activity toward N-linked and O-mannosyl glycan core structures and that its brain-specific gene expression is regulated by epigenetic histone modifications.	o-mannosyl glycan	187-204	mannoside acetylglucosaminyltransferase 5	Mus musculus	75-80
24742675-3	2014	Herein we report that Mgat5(-/-) mice display diminished glycemic response to exogenous glucagon, together with increased insulin sensitivity.	Glucagon	88-96	mannoside acetylglucosaminyltransferase 5	Mus musculus	22-27
24742675-7	2014	Finally, oral GlcNAc supplementation rescued the glucagon response in Mgat5(-/-) hepatocytes and mice, as well as glycolytic metabolites and UDP-GlcNAc levels in liver.	2-acetamido-2-deoxy-4-O-(beta-2-acetamid-2-deoxyglucopyranosyl)glucopyranose	14-20	mannoside acetylglucosaminyltransferase 5	Mus musculus	70-75
23960081-1	2013	Our previous studies on a beta1,6-N-acetylglucosaminyltransferase, GnT-IX (GnT-Vb), a homolog of GnT-V, indicated that the enzyme has a broad GlcNAc transfer activity toward N-linked and O-mannosyl glycan core structures and that its brain-specific gene expression is regulated by epigenetic histone modifications.	2-acetamido-2-deoxy-4-O-(beta-2-acetamid-2-deoxyglucopyranosyl)glucopyranose	142-148	mannoside acetylglucosaminyltransferase 5	Mus musculus	75-80
23798564-3	2013	Here, we induced mouse liver fibrosis by ip injections of carbon tetrachloride (CCl4) or thioacetamide (TAA) and observed significant increase of hepatic GnT-V during the processes of liver fibrogenesis.	Carbon Tetrachloride	58-78	mannoside acetylglucosaminyltransferase 5	Mus musculus	154-159
23960081-1	2013	Our previous studies on a beta1,6-N-acetylglucosaminyltransferase, GnT-IX (GnT-Vb), a homolog of GnT-V, indicated that the enzyme has a broad GlcNAc transfer activity toward N-linked and O-mannosyl glycan core structures and that its brain-specific gene expression is regulated by epigenetic histone modifications.	n-linked	174-182	mannoside acetylglucosaminyltransferase 5	Mus musculus	75-80
23798564-3	2013	Here, we induced mouse liver fibrosis by ip injections of carbon tetrachloride (CCl4) or thioacetamide (TAA) and observed significant increase of hepatic GnT-V during the processes of liver fibrogenesis.	Carbon Tetrachloride	80-84	mannoside acetylglucosaminyltransferase 5	Mus musculus	154-159
23798564-6	2013	Adenovirus-mediated delivery of GnT-V siRNA dramatically reduced the GnT-V expression in fibrotic liver and activated HSC in vivo and consequently alleviated CCl4- or TAA-induced liver fibrosis as assessed through collagen deposition and profiles of profibrogenic markers.	Carbon Tetrachloride	158-162	mannoside acetylglucosaminyltransferase 5	Mus musculus	32-37
23798564-8	2013	The suppression of TGF-beta/Smad signaling in HSCs correlated with the decrease of GnT-V-modified beta1,6-branched N-glycan on TGF-beta receptors.	beta1,6-branched n-glycan	98-123	mannoside acetylglucosaminyltransferase 5	Mus musculus	83-88
23351704-4	2013	Here we describe linked intronic variants of MGAT5 that are associated with reduced N-glycan branching, CTLA-4 surface expression and MS (p=5.79x10(-9), n=7,741), the latter additive with the MGAT1, IL2RA and IL7RA MS risk variants (p=1.76x10(-9), OR=0.67-1.83, n=3,518).	n-glycan	84-92	mannoside acetylglucosaminyltransferase 5	Mus musculus	45-50
22294551-1	2012	N-Acetylglucosaminyltransferase V (GnT-V), catalyzing beta1-6 branching in asparagine-linked oligosaccharides, is one of the most important glycosyltransferases involved in tumor metastasis and carcinogenesis.	asparagine-linked oligosaccharides	75-109	mannoside acetylglucosaminyltransferase 5	Mus musculus	0-33
23101508-1	2012	Oligosaccharide modification by N-acetylglucosaminyltransferase- V (GnT-V), a glycosyltransferase encoded by the Mgat5 gene that catalyzes the formation of beta1,6GlcNAc (N-acetylglucosamine) branches on N-glycans, is thought to be associated with cancer growth and metastasis.	Oligosaccharides	0-15	mannoside acetylglucosaminyltransferase 5	Mus musculus	32-66
23101508-1	2012	Oligosaccharide modification by N-acetylglucosaminyltransferase- V (GnT-V), a glycosyltransferase encoded by the Mgat5 gene that catalyzes the formation of beta1,6GlcNAc (N-acetylglucosamine) branches on N-glycans, is thought to be associated with cancer growth and metastasis.	Oligosaccharides	0-15	mannoside acetylglucosaminyltransferase 5	Mus musculus	68-73
23101508-1	2012	Oligosaccharide modification by N-acetylglucosaminyltransferase- V (GnT-V), a glycosyltransferase encoded by the Mgat5 gene that catalyzes the formation of beta1,6GlcNAc (N-acetylglucosamine) branches on N-glycans, is thought to be associated with cancer growth and metastasis.	Oligosaccharides	0-15	mannoside acetylglucosaminyltransferase 5	Mus musculus	113-118
23101508-1	2012	Oligosaccharide modification by N-acetylglucosaminyltransferase- V (GnT-V), a glycosyltransferase encoded by the Mgat5 gene that catalyzes the formation of beta1,6GlcNAc (N-acetylglucosamine) branches on N-glycans, is thought to be associated with cancer growth and metastasis.	beta1,6glcnac	156-169	mannoside acetylglucosaminyltransferase 5	Mus musculus	32-66
23101508-1	2012	Oligosaccharide modification by N-acetylglucosaminyltransferase- V (GnT-V), a glycosyltransferase encoded by the Mgat5 gene that catalyzes the formation of beta1,6GlcNAc (N-acetylglucosamine) branches on N-glycans, is thought to be associated with cancer growth and metastasis.	beta1,6glcnac	156-169	mannoside acetylglucosaminyltransferase 5	Mus musculus	68-73
23101508-1	2012	Oligosaccharide modification by N-acetylglucosaminyltransferase- V (GnT-V), a glycosyltransferase encoded by the Mgat5 gene that catalyzes the formation of beta1,6GlcNAc (N-acetylglucosamine) branches on N-glycans, is thought to be associated with cancer growth and metastasis.	beta1,6glcnac	156-169	mannoside acetylglucosaminyltransferase 5	Mus musculus	113-118
22716246-1	2012	Oligosaccharide modification by N-acetylglucosaminyltransferase-V (GnT-V), a glycosyltransferase encoded by the Mgat5 gene that catalyses the formation of beta1,6 GlcNAc (N-acetylglucosamine) branches on N-glycans, is thought to be associated with cancer growth and metastasis.	Oligosaccharides	0-15	mannoside acetylglucosaminyltransferase 5	Mus musculus	32-65
22716246-1	2012	Oligosaccharide modification by N-acetylglucosaminyltransferase-V (GnT-V), a glycosyltransferase encoded by the Mgat5 gene that catalyses the formation of beta1,6 GlcNAc (N-acetylglucosamine) branches on N-glycans, is thought to be associated with cancer growth and metastasis.	Oligosaccharides	0-15	mannoside acetylglucosaminyltransferase 5	Mus musculus	67-72
22716246-1	2012	Oligosaccharide modification by N-acetylglucosaminyltransferase-V (GnT-V), a glycosyltransferase encoded by the Mgat5 gene that catalyses the formation of beta1,6 GlcNAc (N-acetylglucosamine) branches on N-glycans, is thought to be associated with cancer growth and metastasis.	Oligosaccharides	0-15	mannoside acetylglucosaminyltransferase 5	Mus musculus	112-117
22716246-1	2012	Oligosaccharide modification by N-acetylglucosaminyltransferase-V (GnT-V), a glycosyltransferase encoded by the Mgat5 gene that catalyses the formation of beta1,6 GlcNAc (N-acetylglucosamine) branches on N-glycans, is thought to be associated with cancer growth and metastasis.	beta1,6 glcnac	155-169	mannoside acetylglucosaminyltransferase 5	Mus musculus	32-65
22716246-1	2012	Oligosaccharide modification by N-acetylglucosaminyltransferase-V (GnT-V), a glycosyltransferase encoded by the Mgat5 gene that catalyses the formation of beta1,6 GlcNAc (N-acetylglucosamine) branches on N-glycans, is thought to be associated with cancer growth and metastasis.	beta1,6 glcnac	155-169	mannoside acetylglucosaminyltransferase 5	Mus musculus	67-72
22716246-1	2012	Oligosaccharide modification by N-acetylglucosaminyltransferase-V (GnT-V), a glycosyltransferase encoded by the Mgat5 gene that catalyses the formation of beta1,6 GlcNAc (N-acetylglucosamine) branches on N-glycans, is thought to be associated with cancer growth and metastasis.	beta1,6 glcnac	155-169	mannoside acetylglucosaminyltransferase 5	Mus musculus	112-117
22716246-1	2012	Oligosaccharide modification by N-acetylglucosaminyltransferase-V (GnT-V), a glycosyltransferase encoded by the Mgat5 gene that catalyses the formation of beta1,6 GlcNAc (N-acetylglucosamine) branches on N-glycans, is thought to be associated with cancer growth and metastasis.	Acetylglucosamine	173-190	mannoside acetylglucosaminyltransferase 5	Mus musculus	32-65
22716246-1	2012	Oligosaccharide modification by N-acetylglucosaminyltransferase-V (GnT-V), a glycosyltransferase encoded by the Mgat5 gene that catalyses the formation of beta1,6 GlcNAc (N-acetylglucosamine) branches on N-glycans, is thought to be associated with cancer growth and metastasis.	Acetylglucosamine	173-190	mannoside acetylglucosaminyltransferase 5	Mus musculus	67-72
22716246-1	2012	Oligosaccharide modification by N-acetylglucosaminyltransferase-V (GnT-V), a glycosyltransferase encoded by the Mgat5 gene that catalyses the formation of beta1,6 GlcNAc (N-acetylglucosamine) branches on N-glycans, is thought to be associated with cancer growth and metastasis.	Acetylglucosamine	173-190	mannoside acetylglucosaminyltransferase 5	Mus musculus	112-117
22716246-1	2012	Oligosaccharide modification by N-acetylglucosaminyltransferase-V (GnT-V), a glycosyltransferase encoded by the Mgat5 gene that catalyses the formation of beta1,6 GlcNAc (N-acetylglucosamine) branches on N-glycans, is thought to be associated with cancer growth and metastasis.	n-glycans	204-213	mannoside acetylglucosaminyltransferase 5	Mus musculus	32-65
22716246-1	2012	Oligosaccharide modification by N-acetylglucosaminyltransferase-V (GnT-V), a glycosyltransferase encoded by the Mgat5 gene that catalyses the formation of beta1,6 GlcNAc (N-acetylglucosamine) branches on N-glycans, is thought to be associated with cancer growth and metastasis.	n-glycans	204-213	mannoside acetylglucosaminyltransferase 5	Mus musculus	67-72
22716246-1	2012	Oligosaccharide modification by N-acetylglucosaminyltransferase-V (GnT-V), a glycosyltransferase encoded by the Mgat5 gene that catalyses the formation of beta1,6 GlcNAc (N-acetylglucosamine) branches on N-glycans, is thought to be associated with cancer growth and metastasis.	n-glycans	204-213	mannoside acetylglucosaminyltransferase 5	Mus musculus	112-117
22716246-2	2012	Overexpression of GnT-V in cancer cells enhances the signalling of growth factors such as epidermal growth factor (EGF) and transforming growth factor-beta by increasing galectin-3 binding to polylactosamine structures on receptor N-glycans.	polylactosamine	192-207	mannoside acetylglucosaminyltransferase 5	Mus musculus	18-23
22716246-2	2012	Overexpression of GnT-V in cancer cells enhances the signalling of growth factors such as epidermal growth factor (EGF) and transforming growth factor-beta by increasing galectin-3 binding to polylactosamine structures on receptor N-glycans.	n-glycans	231-240	mannoside acetylglucosaminyltransferase 5	Mus musculus	18-23
22716246-8	2012	Although the skin of Mgat5(-/-) mice appeared normal, epidermal hyperplasia and proliferation of keratinocytes induced by the phorbol ester 12-O-tetradecanoyl phorbol-13-acetate (TPA) were downregulated in these mutants.	Phorbol Esters	126-139	mannoside acetylglucosaminyltransferase 5	Mus musculus	21-26
22716246-8	2012	Although the skin of Mgat5(-/-) mice appeared normal, epidermal hyperplasia and proliferation of keratinocytes induced by the phorbol ester 12-O-tetradecanoyl phorbol-13-acetate (TPA) were downregulated in these mutants.	Tetradecanoylphorbol Acetate	140-177	mannoside acetylglucosaminyltransferase 5	Mus musculus	21-26
22716246-11	2012	These results indicate that a high expression of GnT-V in keratinocytes contributes to HB-EGF-mediated epidermal hyperproliferation by inhibiting endocytosis of EGF receptors bearing beta1,6 GlcNAc on their N-glycans.	Acetylglucosamine	191-197	mannoside acetylglucosaminyltransferase 5	Mus musculus	49-54
22716246-11	2012	These results indicate that a high expression of GnT-V in keratinocytes contributes to HB-EGF-mediated epidermal hyperproliferation by inhibiting endocytosis of EGF receptors bearing beta1,6 GlcNAc on their N-glycans.	n-glycans	207-216	mannoside acetylglucosaminyltransferase 5	Mus musculus	49-54
23001868-9	2013	Number of Ets1, Mgat4a, Mgat4b, and Mgat5 transcripts increased considerably in DEN-injected mice, however, a non-significant decrease was observed after 5D11D4-treatment.	Diethylnitrosamine	80-83	mannoside acetylglucosaminyltransferase 5	Mus musculus	36-41
23101508-1	2012	Oligosaccharide modification by N-acetylglucosaminyltransferase- V (GnT-V), a glycosyltransferase encoded by the Mgat5 gene that catalyzes the formation of beta1,6GlcNAc (N-acetylglucosamine) branches on N-glycans, is thought to be associated with cancer growth and metastasis.	Acetylglucosamine	172-190	mannoside acetylglucosaminyltransferase 5	Mus musculus	32-66
23101508-1	2012	Oligosaccharide modification by N-acetylglucosaminyltransferase- V (GnT-V), a glycosyltransferase encoded by the Mgat5 gene that catalyzes the formation of beta1,6GlcNAc (N-acetylglucosamine) branches on N-glycans, is thought to be associated with cancer growth and metastasis.	Acetylglucosamine	172-190	mannoside acetylglucosaminyltransferase 5	Mus musculus	68-73
23101508-1	2012	Oligosaccharide modification by N-acetylglucosaminyltransferase- V (GnT-V), a glycosyltransferase encoded by the Mgat5 gene that catalyzes the formation of beta1,6GlcNAc (N-acetylglucosamine) branches on N-glycans, is thought to be associated with cancer growth and metastasis.	Acetylglucosamine	172-190	mannoside acetylglucosaminyltransferase 5	Mus musculus	113-118
23101508-1	2012	Oligosaccharide modification by N-acetylglucosaminyltransferase- V (GnT-V), a glycosyltransferase encoded by the Mgat5 gene that catalyzes the formation of beta1,6GlcNAc (N-acetylglucosamine) branches on N-glycans, is thought to be associated with cancer growth and metastasis.	n-glycans	204-213	mannoside acetylglucosaminyltransferase 5	Mus musculus	32-66
23101508-1	2012	Oligosaccharide modification by N-acetylglucosaminyltransferase- V (GnT-V), a glycosyltransferase encoded by the Mgat5 gene that catalyzes the formation of beta1,6GlcNAc (N-acetylglucosamine) branches on N-glycans, is thought to be associated with cancer growth and metastasis.	n-glycans	204-213	mannoside acetylglucosaminyltransferase 5	Mus musculus	68-73
23101508-1	2012	Oligosaccharide modification by N-acetylglucosaminyltransferase- V (GnT-V), a glycosyltransferase encoded by the Mgat5 gene that catalyzes the formation of beta1,6GlcNAc (N-acetylglucosamine) branches on N-glycans, is thought to be associated with cancer growth and metastasis.	n-glycans	204-213	mannoside acetylglucosaminyltransferase 5	Mus musculus	113-118
23101508-2	2012	Overexpression of GnT-V in cancer cells enhances the signaling of growth factors such as epidermal growth factor by increasing galectin-3 binding to polylactosamine structures on receptor N-glycans.	polylactosamine	149-164	mannoside acetylglucosaminyltransferase 5	Mus musculus	18-23
23101508-2	2012	Overexpression of GnT-V in cancer cells enhances the signaling of growth factors such as epidermal growth factor by increasing galectin-3 binding to polylactosamine structures on receptor N-glycans.	n-glycans	188-197	mannoside acetylglucosaminyltransferase 5	Mus musculus	18-23
22715095-10	2012	These results demonstrate that GnT-V is involved in synthesizing branched O-mannosyl glycans in brain, but the function of these branched O-mannosyl structures is unresolved using mice that lack these glycosyltransferases.	branched o-mannosyl glycans	65-92	mannoside acetylglucosaminyltransferase 5	Mus musculus	31-36
22665489-1	2012	Changes in the levels of N-acetylglucosaminyltransferase V (GnT-V) can alter the function of several types of cell surface receptors and adhesion molecules by causing altered N-linked glycan branching.	n-linked glycan	175-190	mannoside acetylglucosaminyltransferase 5	Mus musculus	25-58
22665489-1	2012	Changes in the levels of N-acetylglucosaminyltransferase V (GnT-V) can alter the function of several types of cell surface receptors and adhesion molecules by causing altered N-linked glycan branching.	n-linked glycan	175-190	mannoside acetylglucosaminyltransferase 5	Mus musculus	60-65
22294551-1	2012	N-Acetylglucosaminyltransferase V (GnT-V), catalyzing beta1-6 branching in asparagine-linked oligosaccharides, is one of the most important glycosyltransferases involved in tumor metastasis and carcinogenesis.	asparagine-linked oligosaccharides	75-109	mannoside acetylglucosaminyltransferase 5	Mus musculus	35-40
21911487-4	2011	Here, the involvement of UDP-N-acetylglucosamine:alpha-6-D-mannoside beta1,6-N-acetylglucosaminyltransferase V (MGAT5)-modified N-glycans in eosinophil and neutrophil recruitment during allergic airway inflammation was investigated.	Uridine Diphosphate N-Acetylglucosamine	25-48	mannoside acetylglucosaminyltransferase 5	Mus musculus	112-117
21911487-4	2011	Here, the involvement of UDP-N-acetylglucosamine:alpha-6-D-mannoside beta1,6-N-acetylglucosaminyltransferase V (MGAT5)-modified N-glycans in eosinophil and neutrophil recruitment during allergic airway inflammation was investigated.	n-glycans	128-137	mannoside acetylglucosaminyltransferase 5	Mus musculus	69-110
21911487-4	2011	Here, the involvement of UDP-N-acetylglucosamine:alpha-6-D-mannoside beta1,6-N-acetylglucosaminyltransferase V (MGAT5)-modified N-glycans in eosinophil and neutrophil recruitment during allergic airway inflammation was investigated.	n-glycans	128-137	mannoside acetylglucosaminyltransferase 5	Mus musculus	112-117
21911487-7	2011	This increased neutrophil recruitment was also observed in LPS- and thioglycollate (TG)-induced inflammation in Mgat5(-/-) mice.	Thioglycolates	68-82	mannoside acetylglucosaminyltransferase 5	Mus musculus	112-117
21911487-7	2011	This increased neutrophil recruitment was also observed in LPS- and thioglycollate (TG)-induced inflammation in Mgat5(-/-) mice.	Thioglycolates	84-86	mannoside acetylglucosaminyltransferase 5	Mus musculus	112-117
21911487-8	2011	Furthermore, there was significantly increased recruitment of infused Mgat5(-/-) neutrophils compared with WT neutrophils in the peritoneal cavity of TG-exposed WT mice.	Thioglycolates	150-152	mannoside acetylglucosaminyltransferase 5	Mus musculus	70-75
21911487-9	2011	Mgat5(-/-) neutrophils demonstrated enhanced adhesion to P-selectin as well as increased migration toward keratinocyte-derived chemokine compared with WT neutrophils in vitro along with increased calcium mobilization upon activation and expression of elevated levels of CXCR2, which may contribute to the increased neutrophil recruitment.	Calcium	196-203	mannoside acetylglucosaminyltransferase 5	Mus musculus	0-5
21911487-10	2011	These data indicate an important role for MGAT5-modified N-glycans in differential regulation of eosinophil and neutrophil recruitment during allergic airway inflammation.	n-glycans	57-66	mannoside acetylglucosaminyltransferase 5	Mus musculus	42-47
21697088-1	2011	N-Acetylglucosaminyltransferase V (GnT-V) catalyzes the beta1,6 branching of N-acetylglucosamine on N-glycans.	Acetylglucosamine	77-96	mannoside acetylglucosaminyltransferase 5	Mus musculus	0-33
21767537-2	2011	To elucidate the role of N-glycans on malaria parasite infection, we induced experimental murine malaria infection (using Plasmodium berghei ANKA) in mice deficient in N-acetylglucosaminyltransferase V (Mgat5), which is one of the enzymes involved in beta1,6-GlcNAc N-glycan biosynthesis.	n-glycans	25-34	mannoside acetylglucosaminyltransferase 5	Mus musculus	168-201
21767537-2	2011	To elucidate the role of N-glycans on malaria parasite infection, we induced experimental murine malaria infection (using Plasmodium berghei ANKA) in mice deficient in N-acetylglucosaminyltransferase V (Mgat5), which is one of the enzymes involved in beta1,6-GlcNAc N-glycan biosynthesis.	beta1,6-glcnac	251-265	mannoside acetylglucosaminyltransferase 5	Mus musculus	168-201
21767537-2	2011	To elucidate the role of N-glycans on malaria parasite infection, we induced experimental murine malaria infection (using Plasmodium berghei ANKA) in mice deficient in N-acetylglucosaminyltransferase V (Mgat5), which is one of the enzymes involved in beta1,6-GlcNAc N-glycan biosynthesis.	n-glycan	25-33	mannoside acetylglucosaminyltransferase 5	Mus musculus	168-201
21697088-1	2011	N-Acetylglucosaminyltransferase V (GnT-V) catalyzes the beta1,6 branching of N-acetylglucosamine on N-glycans.	Acetylglucosamine	77-96	mannoside acetylglucosaminyltransferase 5	Mus musculus	35-40
21697088-1	2011	N-Acetylglucosaminyltransferase V (GnT-V) catalyzes the beta1,6 branching of N-acetylglucosamine on N-glycans.	n-glycans	100-109	mannoside acetylglucosaminyltransferase 5	Mus musculus	0-33
21697088-1	2011	N-Acetylglucosaminyltransferase V (GnT-V) catalyzes the beta1,6 branching of N-acetylglucosamine on N-glycans.	n-glycans	100-109	mannoside acetylglucosaminyltransferase 5	Mus musculus	35-40
18292539-1	2008	N-acetylglucosaminyltransferase V (Mgat5 or GnT-V) is an enzyme that catalyzes beta1-6 branching of N-acetylglucosamine on asparagine (N)-linked oligosaccharides (N-glycan) of cell proteins.	asparagine (n)-linked oligosaccharides	123-161	mannoside acetylglucosaminyltransferase 5	Mus musculus	0-33
22389815-3	2011	N-glycan branching by Mgat5 regulates interaction of surface glycoproteins with galectins, forming a molecular lattice that differentially controls the concentration of surface glycoproteins.	n-glycan	0-8	mannoside acetylglucosaminyltransferase 5	Mus musculus	22-27
22389815-5	2011	Non-T cells also contribute to MS pathogenesis and express abundant Mgat5 branched N-glycans.	n-glycans	83-92	mannoside acetylglucosaminyltransferase 5	Mus musculus	68-73
21078982-1	2010	The expression of an enzyme, GnT-V, that catalyzes a specific posttranslational modification of a family of glycoproteins, namely a branched N-glycan, is transcriptionally up-regulated during breast carcinoma oncogenesis.	n-glycan	141-149	mannoside acetylglucosaminyltransferase 5	Mus musculus	29-34
21629267-2	2011	In mice, N-glycan branching by the Golgi enzymes Mgat1 and/or Mgat5 prevents T cell hyperactivity, cytotoxic T-lymphocyte antigen 4 (CTLA-4) endocytosis, spontaneous inflammatory demyelination and neurodegeneration, the latter pathologies characteristic of MS.	n-glycan	9-17	mannoside acetylglucosaminyltransferase 5	Mus musculus	62-67
17883406-2	2008	The products of Golgi UDP-GlcNAc:N-acetylglucosaminyltransferases (encoded by Mgat1, Mgat2, Mgat4 and Mgat5) act sequentially to generate the GlcNAc-branched complex-type N-glycans on glycoprotein receptors.	2-acetamido-2-deoxy-4-O-(beta-2-acetamid-2-deoxyglucopyranosyl)glucopyranose	26-32	mannoside acetylglucosaminyltransferase 5	Mus musculus	102-107
17883406-2	2008	The products of Golgi UDP-GlcNAc:N-acetylglucosaminyltransferases (encoded by Mgat1, Mgat2, Mgat4 and Mgat5) act sequentially to generate the GlcNAc-branched complex-type N-glycans on glycoprotein receptors.	n-glycans	171-180	mannoside acetylglucosaminyltransferase 5	Mus musculus	102-107
17883406-8	2008	Comparable increase in plasma corticosterone of Mgat5(+/+) and Mgat5(-/-) mice in response to acute stress shows an intact function of the hypothalamus-pituitary-adrenal axis.	Corticosterone	30-44	mannoside acetylglucosaminyltransferase 5	Mus musculus	48-53
17883406-10	2008	Our results indicate that Mgat5 modification of complex-type N-glycans on CNS glycoproteins is involved in the regulation of depression-like behavior.	n-glycans	61-70	mannoside acetylglucosaminyltransferase 5	Mus musculus	26-31
18292539-1	2008	N-acetylglucosaminyltransferase V (Mgat5 or GnT-V) is an enzyme that catalyzes beta1-6 branching of N-acetylglucosamine on asparagine (N)-linked oligosaccharides (N-glycan) of cell proteins.	Acetylglucosamine	100-119	mannoside acetylglucosaminyltransferase 5	Mus musculus	0-33
18292539-1	2008	N-acetylglucosaminyltransferase V (Mgat5 or GnT-V) is an enzyme that catalyzes beta1-6 branching of N-acetylglucosamine on asparagine (N)-linked oligosaccharides (N-glycan) of cell proteins.	Acetylglucosamine	100-119	mannoside acetylglucosaminyltransferase 5	Mus musculus	35-40
18292539-1	2008	N-acetylglucosaminyltransferase V (Mgat5 or GnT-V) is an enzyme that catalyzes beta1-6 branching of N-acetylglucosamine on asparagine (N)-linked oligosaccharides (N-glycan) of cell proteins.	Acetylglucosamine	100-119	mannoside acetylglucosaminyltransferase 5	Mus musculus	44-49
18292539-1	2008	N-acetylglucosaminyltransferase V (Mgat5 or GnT-V) is an enzyme that catalyzes beta1-6 branching of N-acetylglucosamine on asparagine (N)-linked oligosaccharides (N-glycan) of cell proteins.	asparagine (n)-linked oligosaccharides	123-161	mannoside acetylglucosaminyltransferase 5	Mus musculus	35-40
18292539-1	2008	N-acetylglucosaminyltransferase V (Mgat5 or GnT-V) is an enzyme that catalyzes beta1-6 branching of N-acetylglucosamine on asparagine (N)-linked oligosaccharides (N-glycan) of cell proteins.	asparagine (n)-linked oligosaccharides	123-161	mannoside acetylglucosaminyltransferase 5	Mus musculus	44-49
18292539-1	2008	N-acetylglucosaminyltransferase V (Mgat5 or GnT-V) is an enzyme that catalyzes beta1-6 branching of N-acetylglucosamine on asparagine (N)-linked oligosaccharides (N-glycan) of cell proteins.	n-glycan	163-171	mannoside acetylglucosaminyltransferase 5	Mus musculus	0-33
18292539-1	2008	N-acetylglucosaminyltransferase V (Mgat5 or GnT-V) is an enzyme that catalyzes beta1-6 branching of N-acetylglucosamine on asparagine (N)-linked oligosaccharides (N-glycan) of cell proteins.	n-glycan	163-171	mannoside acetylglucosaminyltransferase 5	Mus musculus	35-40
18292539-1	2008	N-acetylglucosaminyltransferase V (Mgat5 or GnT-V) is an enzyme that catalyzes beta1-6 branching of N-acetylglucosamine on asparagine (N)-linked oligosaccharides (N-glycan) of cell proteins.	n-glycan	163-171	mannoside acetylglucosaminyltransferase 5	Mus musculus	44-49
18292539-2	2008	The levels of Mgat5 glycan products commonly are increased in malignancies.	Polysaccharides	20-26	mannoside acetylglucosaminyltransferase 5	Mus musculus	14-19
18292539-5	2008	The results showed that blocking expression of Mgat5-modified glycans in MA782 cells significantly suppressed tumor progression both in vivo and in vitro, strongly stimulated Th1 cytokine production, and enhanced opsonophagocytic capability of macrophages in vivo.	Polysaccharides	62-69	mannoside acetylglucosaminyltransferase 5	Mus musculus	47-52
18292539-6	2008	Importantly, reduction of complex N-glycans on MA782 tumor cells by Mgat5-shRNA resulted in significantly increased proliferation and CD45 surface expression of CD4+ T cells.	n-glycans	34-43	mannoside acetylglucosaminyltransferase 5	Mus musculus	68-73
18292539-7	2008	Our data suggest Mgat5-shRNA could serve as a useful tool to treat breast cancer as well as a powerful tool for the functional investigation of N-glycans and glycoprotein synthesis.	n-glycans	144-153	mannoside acetylglucosaminyltransferase 5	Mus musculus	17-22
17483135-1	2007	Golgi beta1,6-N-acetylglucosaminyltransferase V (Mgat5) produces beta1,6GlcNAc-branched N-glycans on glycoproteins, which increases their affinity for galectins and opposes loss from the cell surface to constitutive endocytosis.	beta1,6glcnac-branched n-glycans	65-97	mannoside acetylglucosaminyltransferase 5	Mus musculus	6-47
18060576-2	2008	Using small interfering RNA against GnT-V, we found that the expression of GnT-V and beta1,6GlcNAc branching were significantly reduced which was particularly accompanied by the arrest in both cell migration and invasion as compared to the negative control.	beta1,6glcnac	85-98	mannoside acetylglucosaminyltransferase 5	Mus musculus	36-41
17942907-1	2007	Golgi beta1,6N-acetylglucosaminyltransferase V (Mgat5) produces beta1,6GlcNAc-branched complex N-glycans on cell surface glycoproteins that bind to galectins and promote surface residency of glycoproteins, including cytokine receptors.	n-glycans	95-104	mannoside acetylglucosaminyltransferase 5	Mus musculus	48-53
17942907-5	2007	Mgat5-/- tumor cells were comparatively hypersensitive to the ROS inducer 2,3-dimethoxy-1,4-naphthoquinone, hyposensitive to tyrosine kinase inhibitors, to Golgi disruption by brefeldin A, and to mitotic arrest by colcemid, hydroxyurea, and camptothecin.	Reactive Oxygen Species	62-65	mannoside acetylglucosaminyltransferase 5	Mus musculus	0-5
17942907-5	2007	Mgat5-/- tumor cells were comparatively hypersensitive to the ROS inducer 2,3-dimethoxy-1,4-naphthoquinone, hyposensitive to tyrosine kinase inhibitors, to Golgi disruption by brefeldin A, and to mitotic arrest by colcemid, hydroxyurea, and camptothecin.	2,3-dimethoxy-1,4-naphthoquinone	74-106	mannoside acetylglucosaminyltransferase 5	Mus musculus	0-5
17942907-5	2007	Mgat5-/- tumor cells were comparatively hypersensitive to the ROS inducer 2,3-dimethoxy-1,4-naphthoquinone, hyposensitive to tyrosine kinase inhibitors, to Golgi disruption by brefeldin A, and to mitotic arrest by colcemid, hydroxyurea, and camptothecin.	Brefeldin A	176-187	mannoside acetylglucosaminyltransferase 5	Mus musculus	0-5
17942907-5	2007	Mgat5-/- tumor cells were comparatively hypersensitive to the ROS inducer 2,3-dimethoxy-1,4-naphthoquinone, hyposensitive to tyrosine kinase inhibitors, to Golgi disruption by brefeldin A, and to mitotic arrest by colcemid, hydroxyurea, and camptothecin.	Hydroxyurea	224-235	mannoside acetylglucosaminyltransferase 5	Mus musculus	0-5
17942907-5	2007	Mgat5-/- tumor cells were comparatively hypersensitive to the ROS inducer 2,3-dimethoxy-1,4-naphthoquinone, hyposensitive to tyrosine kinase inhibitors, to Golgi disruption by brefeldin A, and to mitotic arrest by colcemid, hydroxyurea, and camptothecin.	Camptothecin	241-253	mannoside acetylglucosaminyltransferase 5	Mus musculus	0-5
17942907-6	2007	Finally, regulation of ROS, glucose uptake, and sensitivities to EGF and TGF-beta were rescued by Mgat5 expression or by hexosamine supplementation to complex N-glycan biosynthesis in Mgat5-/- cells.	Reactive Oxygen Species	23-26	mannoside acetylglucosaminyltransferase 5	Mus musculus	98-103
17942907-6	2007	Finally, regulation of ROS, glucose uptake, and sensitivities to EGF and TGF-beta were rescued by Mgat5 expression or by hexosamine supplementation to complex N-glycan biosynthesis in Mgat5-/- cells.	Reactive Oxygen Species	23-26	mannoside acetylglucosaminyltransferase 5	Mus musculus	184-189
17942907-6	2007	Finally, regulation of ROS, glucose uptake, and sensitivities to EGF and TGF-beta were rescued by Mgat5 expression or by hexosamine supplementation to complex N-glycan biosynthesis in Mgat5-/- cells.	Glucose	28-35	mannoside acetylglucosaminyltransferase 5	Mus musculus	98-103
17942907-6	2007	Finally, regulation of ROS, glucose uptake, and sensitivities to EGF and TGF-beta were rescued by Mgat5 expression or by hexosamine supplementation to complex N-glycan biosynthesis in Mgat5-/- cells.	Hexosamines	121-131	mannoside acetylglucosaminyltransferase 5	Mus musculus	184-189
17942907-6	2007	Finally, regulation of ROS, glucose uptake, and sensitivities to EGF and TGF-beta were rescued by Mgat5 expression or by hexosamine supplementation to complex N-glycan biosynthesis in Mgat5-/- cells.	n-glycan	159-167	mannoside acetylglucosaminyltransferase 5	Mus musculus	184-189
17942907-1	2007	Golgi beta1,6N-acetylglucosaminyltransferase V (Mgat5) produces beta1,6GlcNAc-branched complex N-glycans on cell surface glycoproteins that bind to galectins and promote surface residency of glycoproteins, including cytokine receptors.	beta1,6glcnac	64-77	mannoside acetylglucosaminyltransferase 5	Mus musculus	6-46
17942907-1	2007	Golgi beta1,6N-acetylglucosaminyltransferase V (Mgat5) produces beta1,6GlcNAc-branched complex N-glycans on cell surface glycoproteins that bind to galectins and promote surface residency of glycoproteins, including cytokine receptors.	beta1,6glcnac	64-77	mannoside acetylglucosaminyltransferase 5	Mus musculus	48-53
17942907-1	2007	Golgi beta1,6N-acetylglucosaminyltransferase V (Mgat5) produces beta1,6GlcNAc-branched complex N-glycans on cell surface glycoproteins that bind to galectins and promote surface residency of glycoproteins, including cytokine receptors.	n-glycans	95-104	mannoside acetylglucosaminyltransferase 5	Mus musculus	6-46
17483135-1	2007	Golgi beta1,6-N-acetylglucosaminyltransferase V (Mgat5) produces beta1,6GlcNAc-branched N-glycans on glycoproteins, which increases their affinity for galectins and opposes loss from the cell surface to constitutive endocytosis.	beta1,6glcnac-branched n-glycans	65-97	mannoside acetylglucosaminyltransferase 5	Mus musculus	49-54
17483135-3	2007	Here, we demonstrate that Mgat5(-/-) mouse embryonic fibroblasts (MEFs) display reduced sensitivity to anabolic cytokines and reduced glucose uptake and proliferation.	Glucose	134-141	mannoside acetylglucosaminyltransferase 5	Mus musculus	26-31
17483135-4	2007	Mgat5(-/-) mice are also hypoglycemic, resistant to weight gain on a calorie-enriched diet, hypersensitive to fasting, and display increased oxidative respiration and reduced fecundity.	calorie	69-76	mannoside acetylglucosaminyltransferase 5	Mus musculus	0-5
15615721-1	2005	An N-linked glycan often increased during oncogenic transformation contains beta(1,6)-linked GlcNAc, synthesized by the N-acetylglucosaminyltransferase V (GnT-V).	n-linked glycan	3-18	mannoside acetylglucosaminyltransferase 5	Mus musculus	120-153
16556489-1	2006	Beta1,6-acetylglucosaminyltransferase V (GnT-V) forms beta1,6 branching on the trimannosyl terminus of N-glycans, allowing for the production of beta1,6Glc-NAc-bearing oligosaccharides.	Oligosaccharides	168-184	mannoside acetylglucosaminyltransferase 5	Mus musculus	41-46
16556489-8	2006	Treatment of cells with 5-Aza-dC, an inhibitor of DNA methylation, resulted in decreased expression of GnT-V mRNA and beta1,6-branched oligosaccharides along with reduced glycosylation of LAMP-1, a major substrate for GnT-V.	Decitabine	24-32	mannoside acetylglucosaminyltransferase 5	Mus musculus	103-108
16556489-8	2006	Treatment of cells with 5-Aza-dC, an inhibitor of DNA methylation, resulted in decreased expression of GnT-V mRNA and beta1,6-branched oligosaccharides along with reduced glycosylation of LAMP-1, a major substrate for GnT-V.	Decitabine	24-32	mannoside acetylglucosaminyltransferase 5	Mus musculus	218-223
16556489-14	2006	Although our studies involved a highly experimental system, the results further suggest that by whatever mechanism, reduction of GnT-V activity through 5-Aza-dC treatment might provide a new approach towards prevention of metastatic progression.	Decitabine	152-160	mannoside acetylglucosaminyltransferase 5	Mus musculus	129-134
16413118-1	2006	We recently reported on a brain-specific beta1,6-N-acetylglucosaminyltransferase IX (GnT-IX, also referred to as GnT-VB), a GnT-V homologue, which acts on alpha-linked mannose of N-glycans and O-mannosyl glycans.	alpha-linked mannose	155-175	mannoside acetylglucosaminyltransferase 5	Mus musculus	113-118
16413118-1	2006	We recently reported on a brain-specific beta1,6-N-acetylglucosaminyltransferase IX (GnT-IX, also referred to as GnT-VB), a GnT-V homologue, which acts on alpha-linked mannose of N-glycans and O-mannosyl glycans.	n-glycans	179-188	mannoside acetylglucosaminyltransferase 5	Mus musculus	113-118
16413118-1	2006	We recently reported on a brain-specific beta1,6-N-acetylglucosaminyltransferase IX (GnT-IX, also referred to as GnT-VB), a GnT-V homologue, which acts on alpha-linked mannose of N-glycans and O-mannosyl glycans.	o-mannosyl glycans	193-211	mannoside acetylglucosaminyltransferase 5	Mus musculus	113-118
16556489-0	2006	GnT-V expression and metastatic phenotypes in macrophage-melanoma fusion hybrids is down-regulated by 5-Aza-dC: evidence for methylation sensitive, extragenic regulation of GnT-V transcription.	Azacitidine	102-107	mannoside acetylglucosaminyltransferase 5	Mus musculus	0-5
16556489-1	2006	Beta1,6-acetylglucosaminyltransferase V (GnT-V) forms beta1,6 branching on the trimannosyl terminus of N-glycans, allowing for the production of beta1,6Glc-NAc-bearing oligosaccharides.	n-glycans	103-112	mannoside acetylglucosaminyltransferase 5	Mus musculus	41-46
16556489-1	2006	Beta1,6-acetylglucosaminyltransferase V (GnT-V) forms beta1,6 branching on the trimannosyl terminus of N-glycans, allowing for the production of beta1,6Glc-NAc-bearing oligosaccharides.	beta1,6glc-nac	145-159	mannoside acetylglucosaminyltransferase 5	Mus musculus	41-46
15615721-1	2005	An N-linked glycan often increased during oncogenic transformation contains beta(1,6)-linked GlcNAc, synthesized by the N-acetylglucosaminyltransferase V (GnT-V).	n-linked glycan	3-18	mannoside acetylglucosaminyltransferase 5	Mus musculus	155-160
15615721-1	2005	An N-linked glycan often increased during oncogenic transformation contains beta(1,6)-linked GlcNAc, synthesized by the N-acetylglucosaminyltransferase V (GnT-V).	beta(1,6)-linked glcnac	76-99	mannoside acetylglucosaminyltransferase 5	Mus musculus	120-153
15615721-1	2005	An N-linked glycan often increased during oncogenic transformation contains beta(1,6)-linked GlcNAc, synthesized by the N-acetylglucosaminyltransferase V (GnT-V).	beta(1,6)-linked glcnac	76-99	mannoside acetylglucosaminyltransferase 5	Mus musculus	155-160
15615721-5	2005	GnT-V null MEF also showed increased focal adhesion kinase tyrosine phosphorylation, consistent with decreased cell motility on fibronectin-coated plates.	Tyrosine	59-67	mannoside acetylglucosaminyltransferase 5	Mus musculus	0-5
15615721-6	2005	Expression of GnT-V cDNA in the null MEF reversed these abnormal characteristics, indicating the direct involvement of N-glycosylation events in these phenotypic changes.	Nitrogen	22-23	mannoside acetylglucosaminyltransferase 5	Mus musculus	14-19
15585841-7	2004	Swainsonine, an inhibitor of Golgi alpha-mannosidase II, blocked beta1,6GlcNAc N-glycan expression and caused a similar increase in IFN-gamma production by T cells from humans and mice, but no additional enhancement in Mgat5(-/-) T cells.	Swainsonine	0-11	mannoside acetylglucosaminyltransferase 5	Mus musculus	219-224
15585841-0	2004	N-acetylglucosaminyltransferase V (Mgat5)-mediated N-glycosylation negatively regulates Th1 cytokine production by T cells.	Nitrogen	0-1	mannoside acetylglucosaminyltransferase 5	Mus musculus	35-40
15585841-9	2004	These data indicate that negative regulation of TCR signaling by beta1,6GlcNAc N-glycans promotes development of Th2 over Th1 responses, enhances polarization of Th2 cells, and suggests a mechanism for the increased autoimmune disease susceptibility observed in Mgat5(-/-) mice.	beta1,6glcnac	65-78	mannoside acetylglucosaminyltransferase 5	Mus musculus	262-267
15585841-2	2004	We previously demonstrated that beta1,6GlcNAc-branched complex-type (N-acetylglucosaminyltransferase V (Mgat5)) N-glycans on TCR are bound to galectins, an interaction that reduces TCR signaling by opposing agonist-induced TCR clustering at the immune synapse.	beta1,6glcnac	32-45	mannoside acetylglucosaminyltransferase 5	Mus musculus	69-102
15585841-9	2004	These data indicate that negative regulation of TCR signaling by beta1,6GlcNAc N-glycans promotes development of Th2 over Th1 responses, enhances polarization of Th2 cells, and suggests a mechanism for the increased autoimmune disease susceptibility observed in Mgat5(-/-) mice.	n-glycans	79-88	mannoside acetylglucosaminyltransferase 5	Mus musculus	262-267
15585841-2	2004	We previously demonstrated that beta1,6GlcNAc-branched complex-type (N-acetylglucosaminyltransferase V (Mgat5)) N-glycans on TCR are bound to galectins, an interaction that reduces TCR signaling by opposing agonist-induced TCR clustering at the immune synapse.	beta1,6glcnac	32-45	mannoside acetylglucosaminyltransferase 5	Mus musculus	104-109
15585841-2	2004	We previously demonstrated that beta1,6GlcNAc-branched complex-type (N-acetylglucosaminyltransferase V (Mgat5)) N-glycans on TCR are bound to galectins, an interaction that reduces TCR signaling by opposing agonist-induced TCR clustering at the immune synapse.	n-glycans	112-121	mannoside acetylglucosaminyltransferase 5	Mus musculus	69-102
15585841-2	2004	We previously demonstrated that beta1,6GlcNAc-branched complex-type (N-acetylglucosaminyltransferase V (Mgat5)) N-glycans on TCR are bound to galectins, an interaction that reduces TCR signaling by opposing agonist-induced TCR clustering at the immune synapse.	n-glycans	112-121	mannoside acetylglucosaminyltransferase 5	Mus musculus	104-109
14561752-3	2003	Increased GnT-V expression resulted in a significant decrease in the rates of calcium-dependent cell-cell adhesion.	Calcium	78-85	mannoside acetylglucosaminyltransferase 5	Mus musculus	10-15
15459394-1	2004	The Golgi enzyme beta1,6 N-acetylglucosaminyltransferase V (Mgat5) is up-regulated in carcinomas and promotes the substitution of N-glycan with poly N-acetyllactosamine, the preferred ligand for galectin-3 (Gal-3).	n-glycan	130-138	mannoside acetylglucosaminyltransferase 5	Mus musculus	17-58
15459394-1	2004	The Golgi enzyme beta1,6 N-acetylglucosaminyltransferase V (Mgat5) is up-regulated in carcinomas and promotes the substitution of N-glycan with poly N-acetyllactosamine, the preferred ligand for galectin-3 (Gal-3).	n-glycan	130-138	mannoside acetylglucosaminyltransferase 5	Mus musculus	60-65
15459394-1	2004	The Golgi enzyme beta1,6 N-acetylglucosaminyltransferase V (Mgat5) is up-regulated in carcinomas and promotes the substitution of N-glycan with poly N-acetyllactosamine, the preferred ligand for galectin-3 (Gal-3).	poly-N-acetyllactosamine	144-168	mannoside acetylglucosaminyltransferase 5	Mus musculus	17-58
15459394-1	2004	The Golgi enzyme beta1,6 N-acetylglucosaminyltransferase V (Mgat5) is up-regulated in carcinomas and promotes the substitution of N-glycan with poly N-acetyllactosamine, the preferred ligand for galectin-3 (Gal-3).	poly-N-acetyllactosamine	144-168	mannoside acetylglucosaminyltransferase 5	Mus musculus	60-65
15459394-3	2004	Gal-3 cross-linked Mgat5-modified N-glycans on epidermal growth factor and transforming growth factor-beta receptors at the cell surface and delayed their removal by constitutive endocytosis.	n-glycans	34-43	mannoside acetylglucosaminyltransferase 5	Mus musculus	19-24
14561752-7	2003	Overexpression of GnT-V sensitized stimulation of tyrosine phosphorylation of catenins by growth factors and expression of v-src, which is consistent with its reduction of cell-cell adhesion.	Tyrosine	50-58	mannoside acetylglucosaminyltransferase 5	Mus musculus	18-23
14561752-5	2003	Overexpression of GnT-V had no effect on the levels of cell surface expression of N-cadherin; however, it did cause a marked enhancement of both beta(1,6) branching and poly-N-acetyllactosamine expression on N-cadherin.	poly-N-acetyllactosamine	169-193	mannoside acetylglucosaminyltransferase 5	Mus musculus	18-23
12417426-0	2002	UDP-N-acetylglucosamine:alpha-6-D-mannoside beta1,6 N-acetylglucosaminyltransferase V (Mgat5) deficient mice.	Uridine Diphosphate N-Acetylglucosamine	0-23	mannoside acetylglucosaminyltransferase 5	Mus musculus	87-92
12417426-4	2002	We found that Mgat5-modified N-glycans on the T cell receptor (TCR) complex bind to galectin-3, sequestering TCR within a multivalent galectin-glycoprotein lattice that impedes antigen-dependent receptor clustering and signal transduction.	n-glycans	29-38	mannoside acetylglucosaminyltransferase 5	Mus musculus	14-19
12417426-0	2002	UDP-N-acetylglucosamine:alpha-6-D-mannoside beta1,6 N-acetylglucosaminyltransferase V (Mgat5) deficient mice.	Uridine Diphosphate N-Acetylglucosamine	0-23	mannoside acetylglucosaminyltransferase 5	Mus musculus	44-85
12417426-5	2002	Integrin receptor clustering and cell motility are also sensitive to changes in Mgat5-dependent N-glycosylation.	Nitrogen	96-97	mannoside acetylglucosaminyltransferase 5	Mus musculus	80-85
12122020-1	2002	N-acetylglucosaminyltransferase V, encoded by the Mgat5 gene, plays an important regulatory role in the synthesis of complex N-glycans, including the Lewis antigens.	n-glycans	125-134	mannoside acetylglucosaminyltransferase 5	Mus musculus	0-33
12122020-1	2002	N-acetylglucosaminyltransferase V, encoded by the Mgat5 gene, plays an important regulatory role in the synthesis of complex N-glycans, including the Lewis antigens.	n-glycans	125-134	mannoside acetylglucosaminyltransferase 5	Mus musculus	50-55
11886845-4	2002	When B16 melanoma cells, which express high levels of GnT-V, were incubated with GlcNAc, the beta1,6-branched oligosaccharide levels were increased, as judged by a lectin blot analysis, in conjunction with an increase in intracellular UDP-GlcNAc.	2-acetamido-2-deoxy-4-O-(beta-2-acetamid-2-deoxyglucopyranosyl)glucopyranose	81-87	mannoside acetylglucosaminyltransferase 5	Mus musculus	54-59
11864986-2	2002	It is well known that beta1-6 GlcNAc branching, a product of UDP-GlcNAc alpha-mannoside beta1-6-N-acetylglucosaminyltransferase (GnT-V), is associated with malignant transformation as the results of such alterations.	Uridine Diphosphate N-Acetylglucosamine	61-71	mannoside acetylglucosaminyltransferase 5	Mus musculus	129-134
11864986-2	2002	It is well known that beta1-6 GlcNAc branching, a product of UDP-GlcNAc alpha-mannoside beta1-6-N-acetylglucosaminyltransferase (GnT-V), is associated with malignant transformation as the results of such alterations.	alpha-mannoside	72-87	mannoside acetylglucosaminyltransferase 5	Mus musculus	129-134
11886845-4	2002	When B16 melanoma cells, which express high levels of GnT-V, were incubated with GlcNAc, the beta1,6-branched oligosaccharide levels were increased, as judged by a lectin blot analysis, in conjunction with an increase in intracellular UDP-GlcNAc.	beta1,6-branched oligosaccharide	93-125	mannoside acetylglucosaminyltransferase 5	Mus musculus	54-59
11886845-4	2002	When B16 melanoma cells, which express high levels of GnT-V, were incubated with GlcNAc, the beta1,6-branched oligosaccharide levels were increased, as judged by a lectin blot analysis, in conjunction with an increase in intracellular UDP-GlcNAc.	Uridine Diphosphate N-Acetylglucosamine	235-245	mannoside acetylglucosaminyltransferase 5	Mus musculus	54-59
11469797-6	2001	The results showed that beta 1,4-GalT widely affects N-glycan processing by competing with GnT-IV, GnT-V, and alpha-mannosidase II in cells and also by some other mechanisms that suppress the conversion of high-mannose-type sugar chains to the hybrid type.	n-glycan	53-61	mannoside acetylglucosaminyltransferase 5	Mus musculus	99-104
11751457-3	2001	Because LAMP-1 is the major carrier of polylactosamine sugar structures, and synthesis of this complex sugar moiety indicates the extent of beta1,6 branch formation by beta1,6-N-acetyl-glucosaminyltransferase V (GnT-V), we analyzed the expression of GnT-V and beta1,6 branching in highly metastatic macrophage-fusion hybrids and compared with poorly metastatic ones.	Sugars	103-108	mannoside acetylglucosaminyltransferase 5	Mus musculus	212-217
11751457-3	2001	Because LAMP-1 is the major carrier of polylactosamine sugar structures, and synthesis of this complex sugar moiety indicates the extent of beta1,6 branch formation by beta1,6-N-acetyl-glucosaminyltransferase V (GnT-V), we analyzed the expression of GnT-V and beta1,6 branching in highly metastatic macrophage-fusion hybrids and compared with poorly metastatic ones.	Sugars	103-108	mannoside acetylglucosaminyltransferase 5	Mus musculus	250-255
10700233-1	2000	Golgi beta1,6N-acetylglucosaminyltransferase V (MGAT5) is required in the biosynthesis of beta1,6GlcNAc-branched N-linked glycans attached to cell surface and secreted glycoproteins.	beta1,6glcnac	90-103	mannoside acetylglucosaminyltransferase 5	Mus musculus	6-46
10700233-1	2000	Golgi beta1,6N-acetylglucosaminyltransferase V (MGAT5) is required in the biosynthesis of beta1,6GlcNAc-branched N-linked glycans attached to cell surface and secreted glycoproteins.	beta1,6glcnac	90-103	mannoside acetylglucosaminyltransferase 5	Mus musculus	48-53
10700233-1	2000	Golgi beta1,6N-acetylglucosaminyltransferase V (MGAT5) is required in the biosynthesis of beta1,6GlcNAc-branched N-linked glycans attached to cell surface and secreted glycoproteins.	n-linked glycans	113-129	mannoside acetylglucosaminyltransferase 5	Mus musculus	6-46
10700233-1	2000	Golgi beta1,6N-acetylglucosaminyltransferase V (MGAT5) is required in the biosynthesis of beta1,6GlcNAc-branched N-linked glycans attached to cell surface and secreted glycoproteins.	n-linked glycans	113-129	mannoside acetylglucosaminyltransferase 5	Mus musculus	48-53
10700233-2	2000	Amounts of MGAT5 glycan products are commonly increased in malignancies, and correlate with disease progression.	Polysaccharides	17-23	mannoside acetylglucosaminyltransferase 5	Mus musculus	11-16
10700233-3	2000	To study the functions of these N-glycans in development and disease, we generated mice deficient in Mgat5 by targeted gene mutation.	n-glycans	32-41	mannoside acetylglucosaminyltransferase 5	Mus musculus	101-106
10700233-6	2000	Furthermore, Mgat5 glycan products stimulated membrane ruffling and phosphatidylinositol 3 kinase-protein kinase B activation, fueling a positive feedback loop that amplified oncogene signaling and tumor growth in vivo.	Polysaccharides	19-25	mannoside acetylglucosaminyltransferase 5	Mus musculus	13-18
11250723-2	2000	Associations linking the importance of glycosylation events to tumor biology, especially the progression to metastatic disease, have been noted over many years, Recently, a mouse model in which beta1,6-N-acetylglucosaminyltransferase V (a rate-limiting enzyme in the N-glycan pathway) has been knocked out, was used to demonstrate the importance of glycosylation in tumor progression.	n-glycan	267-275	mannoside acetylglucosaminyltransferase 5	Mus musculus	194-235
10024661-2	1999	In this study, three mouse mammary cancer cell lines were transfected with an expression vector containing the mouse cDNA for N-acetylglucosaminyltransferase V (GlcNAcT-V EC 2.4.1.155), the glycosyltransferase responsible for initiating beta1-6 branching on Asn-linked carbohydrates.	asn-linked carbohydrates	258-282	mannoside acetylglucosaminyltransferase 5	Mus musculus	126-159
10580127-4	1999	Mgat5 encodes N-acetylglucosaminyltransferase V (GlcNAc-TV), the Golgi enzyme required in the biosynthesis of beta1,6GlcNAc-branched N-glycans.	beta1,6glcnac-branched n-glycans	110-142	mannoside acetylglucosaminyltransferase 5	Mus musculus	0-5
10580127-4	1999	Mgat5 encodes N-acetylglucosaminyltransferase V (GlcNAc-TV), the Golgi enzyme required in the biosynthesis of beta1,6GlcNAc-branched N-glycans.	beta1,6glcnac-branched n-glycans	110-142	mannoside acetylglucosaminyltransferase 5	Mus musculus	14-47
10580127-4	1999	Mgat5 encodes N-acetylglucosaminyltransferase V (GlcNAc-TV), the Golgi enzyme required in the biosynthesis of beta1,6GlcNAc-branched N-glycans.	beta1,6glcnac-branched n-glycans	110-142	mannoside acetylglucosaminyltransferase 5	Mus musculus	49-58
9061364-4	1997	GlcNAc-TIII can also play a regulatory role in N-glycan biosynthesis as addition of the bisecting GlcNAc eliminates the potential for alpha-mannosidase-II, GlcNAc-TII, GlcNAc-TIV, GlcNAc-TV, and core alpha 1-6-fucosyltransferase to act subsequently.	n-glycan	47-55	mannoside acetylglucosaminyltransferase 5	Mus musculus	180-189
9061364-4	1997	GlcNAc-TIII can also play a regulatory role in N-glycan biosynthesis as addition of the bisecting GlcNAc eliminates the potential for alpha-mannosidase-II, GlcNAc-TII, GlcNAc-TIV, GlcNAc-TV, and core alpha 1-6-fucosyltransferase to act subsequently.	Acetylglucosamine	0-6	mannoside acetylglucosaminyltransferase 5	Mus musculus	180-189
2956949-0	1987	Activity of UDP-GlcNAc:alpha-mannoside beta(1,6)N-acetylglucosaminyltransferase (GnT V) in cultured cells using a synthetic trisaccharide acceptor.	Uridine Diphosphate N-Acetylglucosamine	12-22	mannoside acetylglucosaminyltransferase 5	Mus musculus	81-86
8748159-6	1995	This antisera binds selectively to GlcNAc-T V and has been used to visualize B-16 mouse melanoma cell GlcNAc-T V on immunoblots after SDS-PAGE.	Sodium Dodecyl Sulfate	134-137	mannoside acetylglucosaminyltransferase 5	Mus musculus	102-112
35563467-4	2022	To test the importance of complex asparagine-linked glycosylation in NPC1 pathology, we generated NPC1 knock-out mice deficient in MGAT5, a key Golgi-resident glycosyl transferase involved in complex asparagine-linked glycosylation.	Asparagine	34-44	mannoside acetylglucosaminyltransferase 5	Mus musculus	131-136
35563467-4	2022	To test the importance of complex asparagine-linked glycosylation in NPC1 pathology, we generated NPC1 knock-out mice deficient in MGAT5, a key Golgi-resident glycosyl transferase involved in complex asparagine-linked glycosylation.	Asparagine	200-210	mannoside acetylglucosaminyltransferase 5	Mus musculus	131-136
8720078-8	1995	Leukoagglutinin (L-PHA)-reactive oligosaccharides co-localized with GlcNAc-TV transcripts in skin, kidney and intestine, but brain showed unexpectedly low overall staining punctuated by bright staining of the vascular endothelium.	Oligosaccharides	33-49	mannoside acetylglucosaminyltransferase 5	Mus musculus	68-77
7568011-1	1995	The beta 1-6 structure of N-linked oligosaccharides, formed by beta-1,6-N-acetylglucosaminyltransferase (GnT-V), is associated with metastatic potential.	n-linked oligosaccharides	26-51	mannoside acetylglucosaminyltransferase 5	Mus musculus	105-110
7615638-1	1995	Herein, we report that expression of GlcNAc-TV in Mv1Lu cells, an immortalized lung epithelial cell line results in loss of contact-inhibition of cell growth, an effect that was blocked by swainsonine, an inhibitor of Golgi processing enzyme alpha-mannosidase II.	Swainsonine	189-200	mannoside acetylglucosaminyltransferase 5	Mus musculus	37-46
7615638-5	1995	The larger apparent molecular weights of the LAMP-2 glycoprotein and integrin glycoproteins alpha 5, alpha v and beta 1 in the transfected cells indicates that their oligosaccharide chains are substrates for GlcNAc-TV.	Oligosaccharides	166-181	mannoside acetylglucosaminyltransferase 5	Mus musculus	208-217
7630020-1	1995	The beta 1-6 structure of N-oligosaccharides, formed by beta 1-6 N-acetylglucosaminyltransferase (GnT-V), is associated with metastatic potential.	n-oligosaccharides	26-44	mannoside acetylglucosaminyltransferase 5	Mus musculus	98-103
7890758-1	1995	beta-1,6-N-acetylglucosaminyltransferase V (GnT-V) (EC 2.4.1.155) that catalyzes beta-1,6 branching in asparagine-linked oligosaccharides is activated on viral or oncogenic transformation and is associated with tumor metastasis.	asparagine-linked oligosaccharides	103-137	mannoside acetylglucosaminyltransferase 5	Mus musculus	0-42
7890758-1	1995	beta-1,6-N-acetylglucosaminyltransferase V (GnT-V) (EC 2.4.1.155) that catalyzes beta-1,6 branching in asparagine-linked oligosaccharides is activated on viral or oncogenic transformation and is associated with tumor metastasis.	asparagine-linked oligosaccharides	103-137	mannoside acetylglucosaminyltransferase 5	Mus musculus	44-49
7890758-13	1995	These results suggested that TGF beta caused changes in the sugar chains of proteins in melanoma cells by up-regulating GnT-V expression.	Sugars	60-65	mannoside acetylglucosaminyltransferase 5	Mus musculus	120-125
2956949-0	1987	Activity of UDP-GlcNAc:alpha-mannoside beta(1,6)N-acetylglucosaminyltransferase (GnT V) in cultured cells using a synthetic trisaccharide acceptor.	alpha-mannoside	23-38	mannoside acetylglucosaminyltransferase 5	Mus musculus	81-86
2956949-0	1987	Activity of UDP-GlcNAc:alpha-mannoside beta(1,6)N-acetylglucosaminyltransferase (GnT V) in cultured cells using a synthetic trisaccharide acceptor.	Trisaccharides	124-137	mannoside acetylglucosaminyltransferase 5	Mus musculus	81-86
2956949-1	1987	N-acetylglucosaminyltransferase V activity has been measured under saturating conditions in the extracts of seven cultured cell lines using as substrates, UDP-[3H]-GlcNAc and a synthetic 8-methoxylcarbonyloctyl trisaccharide.	udp-[3h]-glcnac	155-170	mannoside acetylglucosaminyltransferase 5	Mus musculus	0-33
2956949-1	1987	N-acetylglucosaminyltransferase V activity has been measured under saturating conditions in the extracts of seven cultured cell lines using as substrates, UDP-[3H]-GlcNAc and a synthetic 8-methoxylcarbonyloctyl trisaccharide.	8-methoxylcarbonyloctyl trisaccharide	187-224	mannoside acetylglucosaminyltransferase 5	Mus musculus	0-33