PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 3676400-2 1987 These mammalian protamines share amino acid sequence homology with mouse protamine 1 (mP1), the tyrosine-containing variant. Tyrosine 96-104 protamine 1 Mus musculus 73-84 35608054-4 2022 Prm1-/- and Prm2-/- sperm show high levels of reactive oxygen species (ROS)-mediated DNA damages and increased histone retention. Reactive Oxygen Species 46-69 protamine 1 Mus musculus 0-4 35608054-4 2022 Prm1-/- and Prm2-/- sperm show high levels of reactive oxygen species (ROS)-mediated DNA damages and increased histone retention. Reactive Oxygen Species 71-74 protamine 1 Mus musculus 0-4 2986684-4 1985 The predicted amino acid sequence of mouse protamine 1 is about 80% homologous to boar protamine and 67% homologous to bull protamine and contains the central, highly basic domain of four arginine clusters found in the trout protamines. Arginine 188-196 protamine 1 Mus musculus 43-54 2442049-5 1987 The fraction of [35S]cysteine- labeled protamine 1 translation product was compared with the fraction of testis poly(A)+ mRNA as protamine 1 mRNA which we measured in dot blots with the use of an SP6 RNA polymerase transcript for protamine 1. Sulfur-35 17-20 protamine 1 Mus musculus 39-50 2442049-5 1987 The fraction of [35S]cysteine- labeled protamine 1 translation product was compared with the fraction of testis poly(A)+ mRNA as protamine 1 mRNA which we measured in dot blots with the use of an SP6 RNA polymerase transcript for protamine 1. Cysteine 21-29 protamine 1 Mus musculus 39-50 8618919-6 1995 These results demonstrate that correct temporal synthesis of Prm1 is necessary for the transition from nucleohistones to nucleoprotamines. nucleohistones 103-117 protamine 1 Mus musculus 61-65 3840106-1 1985 We utilized a cDNA encoding the cysteine-rich, tyrosine-containing mouse protamine, mouse protamine 1 (MP1), to detect the presence of several classes of differentiating germ cells in testicular extracts from wild-type and male sterile mutant mice. Cysteine 32-40 protamine 1 Mus musculus 90-101 3840106-1 1985 We utilized a cDNA encoding the cysteine-rich, tyrosine-containing mouse protamine, mouse protamine 1 (MP1), to detect the presence of several classes of differentiating germ cells in testicular extracts from wild-type and male sterile mutant mice. Tyrosine 47-55 protamine 1 Mus musculus 90-101 31932482-6 2020 Coincident with round spermatid arrest, we find reduced mRNA expression of transition protein (Tnp1 and Tnp2) and protamine (Prm1 and Prm2) genes, which are critical for the specialized maturation of haploid male germ cells called spermiogenesis. Insulin, Isophane 114-123 protamine 1 Mus musculus 125-129 23160479-8 2013 TgSCAR induced premature postnatal spermatogenic development, shown by increased levels of meiotic (Dmc1 and Spo11) and postmeiotic (Capza3 and Prm1) germ cell transcripts, elevated meiotic-postmeiotic germ:Sertoli cell ratios, and accelerated spermatid development. tgscar 0-6 protamine 1 Mus musculus 144-148 25422748-6 2014 The expression of protamine 1 (Prm1) gene was checked as post meiotic marker in differentiated mESCs after 5, 10, 15, 21 and 30 days after RA induction. Tretinoin 139-141 protamine 1 Mus musculus 18-29 25422748-9 2014 The protamine 1 gene was expressed after 21 days of RA induction. Tretinoin 52-54 protamine 1 Mus musculus 4-15 23509752-6 2013 mRNA expression of Stra8, Odf2, Act, and Prm1 was upregulated in iPS cells by retinoic acid or testosterone induction, whereas Oct-4 transcription was reduced in these cells compared to the controls. IPS 65-68 protamine 1 Mus musculus 41-45 23509752-6 2013 mRNA expression of Stra8, Odf2, Act, and Prm1 was upregulated in iPS cells by retinoic acid or testosterone induction, whereas Oct-4 transcription was reduced in these cells compared to the controls. Tretinoin 78-91 protamine 1 Mus musculus 41-45 23509752-6 2013 mRNA expression of Stra8, Odf2, Act, and Prm1 was upregulated in iPS cells by retinoic acid or testosterone induction, whereas Oct-4 transcription was reduced in these cells compared to the controls. Testosterone 95-107 protamine 1 Mus musculus 41-45 21383078-6 2011 Cyclic adenosine monophosphate response element modulator (CREM) and TRF2, key transcription factors for spermiogenesis, are expressed in Tdrd5-deficient round spermatids, but their targets, including Prm1/Prm2/Tnp1, are severely down-regulated, which indicates the importance of IMC/CB-mediated regulation for postmeiotic gene expression. Cyclic AMP 0-30 protamine 1 Mus musculus 201-205 10849508-5 2000 The 17-nucleotide translational control element (TCE) mediates translational repression of the Prm1 mRNA. 17-nucleotide 4-17 protamine 1 Mus musculus 95-99 8185929-4 1994 Newly synthesized mouse protamine 1 (mP1) and the precursor to mouse protamine 2 (pre-mP2) migrated more slowly during electrophoresis than their predominant testicular forms, identified by staining with Coomassie blue R-250. Coomassie brilliant blue R 204-224 protamine 1 Mus musculus 24-35