PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 34356479-7 2021 Azithromycin combinations with either linezolid, ceftriaxone, gentamicin, or cefotaxime provided synergy in 42.1%, 44.7%, 31.6% and 7.9% of the 38 MAC-MRSA isolates, respectively. Cefotaxime 77-87 solute carrier family 9 member A6 Homo sapiens 151-155 2129029-0 1990 Nasal carriage of MRSA: the role of mupirocin and outlook for resistance. Mupirocin 36-45 solute carrier family 9 member A6 Homo sapiens 18-22 2129029-3 1990 During an MRSA outbreak at a London hospital, standard infection control measures failed to prevent colonisation and infection of more than two hundred patients, but the use of mupirocin was associated with epidemiological control. Mupirocin 177-186 solute carrier family 9 member A6 Homo sapiens 10-14 34356479-0 2021 Association of Macrolide Resistance Genotypes and Synergistic Antibiotic Combinations for Combating Macrolide-Resistant MRSA Recovered from Hospitalized Patients. Macrolides 15-24 solute carrier family 9 member A6 Homo sapiens 120-124 33300825-10 2021 The most informative approach targeted solely fluoroquinolones, reporting improvements in relevant Pseudomonas susceptibilities and MRSA, but without sufficient data on other effects of the strategy to assess its overall utility in clinical practice. Fluoroquinolones 46-62 solute carrier family 9 member A6 Homo sapiens 132-136 34791706-7 2022 CONCLUSIONS: Our finding extends the catalog of pathogenic intronic variants affecting SLC9A6 pre-mRNA splicing and provides a basis for the genetic diagnosis of CS. Cesium 162-164 solute carrier family 9 member A6 Homo sapiens 87-93 34718190-0 2021 Distribution of erm genes among MRSA isolates with resistance to clindamycin in a Chinese teaching hospital. Clindamycin 65-76 solute carrier family 9 member A6 Homo sapiens 32-36 34718190-1 2021 The objective of this study was to analyze erythromycin and clindamycin resistance patterns among different MRSA lineages in China. Erythromycin 43-55 solute carrier family 9 member A6 Homo sapiens 108-112 34718190-1 2021 The objective of this study was to analyze erythromycin and clindamycin resistance patterns among different MRSA lineages in China. Clindamycin 60-71 solute carrier family 9 member A6 Homo sapiens 108-112 34718190-4 2021 Additionally, 88.2% (60/68) of the ST59 MRSA isolates and 78.9% (15/19) of the ST239 MRSA isolates had constitutive resistance to clindamycin, while 82.0% (123/150) of the ST5 MRSA isolates showed inducible clindamycin resistance. Clindamycin 130-141 solute carrier family 9 member A6 Homo sapiens 40-44 34718190-4 2021 Additionally, 88.2% (60/68) of the ST59 MRSA isolates and 78.9% (15/19) of the ST239 MRSA isolates had constitutive resistance to clindamycin, while 82.0% (123/150) of the ST5 MRSA isolates showed inducible clindamycin resistance. Clindamycin 130-141 solute carrier family 9 member A6 Homo sapiens 85-89 34718190-4 2021 Additionally, 88.2% (60/68) of the ST59 MRSA isolates and 78.9% (15/19) of the ST239 MRSA isolates had constitutive resistance to clindamycin, while 82.0% (123/150) of the ST5 MRSA isolates showed inducible clindamycin resistance. Clindamycin 207-218 solute carrier family 9 member A6 Homo sapiens 176-180 34718190-8 2021 Summarily, high erythromycin and clindamycin resistance rates were observed in MRSA isolates. Erythromycin 16-28 solute carrier family 9 member A6 Homo sapiens 79-83 34718190-8 2021 Summarily, high erythromycin and clindamycin resistance rates were observed in MRSA isolates. Clindamycin 33-44 solute carrier family 9 member A6 Homo sapiens 79-83 34718190-11 2021 Erythromycin and clindamycin resistance genes transfer between MRSA isolates in healthcare settings remains a problem, and infection control procedures should be applied. Erythromycin 0-12 solute carrier family 9 member A6 Homo sapiens 63-67 34718190-11 2021 Erythromycin and clindamycin resistance genes transfer between MRSA isolates in healthcare settings remains a problem, and infection control procedures should be applied. Clindamycin 17-28 solute carrier family 9 member A6 Homo sapiens 63-67 34153574-0 2021 Design, synthesis and biological evaluation of pleuromutilin-Schiff base hybrids as potent anti-MRSA agents in vitro and in vivo. pleuromutilin 47-60 solute carrier family 9 member A6 Homo sapiens 96-100 34153574-0 2021 Design, synthesis and biological evaluation of pleuromutilin-Schiff base hybrids as potent anti-MRSA agents in vitro and in vivo. Schiff Bases 61-72 solute carrier family 9 member A6 Homo sapiens 96-100 34153574-3 2021 Among these derivatives, compound 60 exhibited superior in vitro antibacterial effect against MRSA (MIC = 0.25 mug/mL) than tiamulin (MIC = 0.5 mug/mL), and compound 60 (-2.28 log10 CFU/mL) also displayed superior in vivo antibacterial efficacy than tiamulin (-1.40 log10 CFU/mL) in reducing MRSA load in the mouse thigh infection model. tiamulin 124-132 solute carrier family 9 member A6 Homo sapiens 292-296 34153574-3 2021 Among these derivatives, compound 60 exhibited superior in vitro antibacterial effect against MRSA (MIC = 0.25 mug/mL) than tiamulin (MIC = 0.5 mug/mL), and compound 60 (-2.28 log10 CFU/mL) also displayed superior in vivo antibacterial efficacy than tiamulin (-1.40 log10 CFU/mL) in reducing MRSA load in the mouse thigh infection model. tiamulin 250-258 solute carrier family 9 member A6 Homo sapiens 292-296 34880951-1 2021 Background: Periprosthetic infection is commonly caused by Staphylococcus aureus and, if resistant to methicillin (MRSA), is associated with increase in severity and costs to patient and healthcare systems. Methicillin 102-113 solute carrier family 9 member A6 Homo sapiens 115-119 34278512-0 2021 Correction to: Natural brominated phenoxyphenols kill persistent and biofilm-incorporated cells of MRSA and other pathogenic bacteria. phenoxyphenols 34-48 solute carrier family 9 member A6 Homo sapiens 99-103 34356479-7 2021 Azithromycin combinations with either linezolid, ceftriaxone, gentamicin, or cefotaxime provided synergy in 42.1%, 44.7%, 31.6% and 7.9% of the 38 MAC-MRSA isolates, respectively. Gentamicins 62-72 solute carrier family 9 member A6 Homo sapiens 151-155 34356479-0 2021 Association of Macrolide Resistance Genotypes and Synergistic Antibiotic Combinations for Combating Macrolide-Resistant MRSA Recovered from Hospitalized Patients. Macrolides 100-109 solute carrier family 9 member A6 Homo sapiens 120-124 34356479-1 2021 Macrolide-resistant methicillin-resistant Staphylococcus aureus (MAC-MRSA) is one of the most clinically relevant pathogens due to its significant ability of resistance acquisition to different antimicrobial agents. Macrolides 0-9 solute carrier family 9 member A6 Homo sapiens 69-73 34356479-9 2021 In conclusion, azithromycin combinations with either linezolid, or ceftriaxone showed synergism in most of the MAC-resistant MRSA clinical isolates. Azithromycin 15-27 solute carrier family 9 member A6 Homo sapiens 125-129 34356479-1 2021 Macrolide-resistant methicillin-resistant Staphylococcus aureus (MAC-MRSA) is one of the most clinically relevant pathogens due to its significant ability of resistance acquisition to different antimicrobial agents. Methicillin 20-31 solute carrier family 9 member A6 Homo sapiens 69-73 34356479-9 2021 In conclusion, azithromycin combinations with either linezolid, or ceftriaxone showed synergism in most of the MAC-resistant MRSA clinical isolates. Linezolid 53-62 solute carrier family 9 member A6 Homo sapiens 125-129 34356479-7 2021 Azithromycin combinations with either linezolid, ceftriaxone, gentamicin, or cefotaxime provided synergy in 42.1%, 44.7%, 31.6% and 7.9% of the 38 MAC-MRSA isolates, respectively. Azithromycin 0-12 solute carrier family 9 member A6 Homo sapiens 151-155 34356479-9 2021 In conclusion, azithromycin combinations with either linezolid, or ceftriaxone showed synergism in most of the MAC-resistant MRSA clinical isolates. Ceftriaxone 67-78 solute carrier family 9 member A6 Homo sapiens 125-129 34356479-7 2021 Azithromycin combinations with either linezolid, ceftriaxone, gentamicin, or cefotaxime provided synergy in 42.1%, 44.7%, 31.6% and 7.9% of the 38 MAC-MRSA isolates, respectively. Linezolid 38-47 solute carrier family 9 member A6 Homo sapiens 151-155 34356479-9 2021 In conclusion, azithromycin combinations with either linezolid, or ceftriaxone showed synergism in most of the MAC-resistant MRSA clinical isolates. mac 111-114 solute carrier family 9 member A6 Homo sapiens 125-129 34356479-7 2021 Azithromycin combinations with either linezolid, ceftriaxone, gentamicin, or cefotaxime provided synergy in 42.1%, 44.7%, 31.6% and 7.9% of the 38 MAC-MRSA isolates, respectively. Ceftriaxone 49-60 solute carrier family 9 member A6 Homo sapiens 151-155 34150881-1 2021 Spread of livestock-associated methicillin resistant Staphylococcus aureus (LA-MRSA) to farmworkers has been recognized as a risk when working in LA-MRSA positive stables, due to LA-MRSA being present on airborne dust particles. Methicillin 31-42 solute carrier family 9 member A6 Homo sapiens 79-83 34201722-3 2021 A secondary objective was to describe the rate of favorable clinical response in patients with bloodstream infections (BSI) due to methicillin-resistant Staphylococcus aureus (MRSA-BSI) receiving ceftaroline. Methicillin 131-142 solute carrier family 9 member A6 Homo sapiens 176-180 34201722-3 2021 A secondary objective was to describe the rate of favorable clinical response in patients with bloodstream infections (BSI) due to methicillin-resistant Staphylococcus aureus (MRSA-BSI) receiving ceftaroline. T 91825 196-207 solute carrier family 9 member A6 Homo sapiens 176-180 34201722-7 2021 Among patients with MRSA-BSI, ceftaroline was used as a first-line therapy and salvage therapy in 25% (3/12) and 75% (9/12) of cases, respectively, and as a monotherapy or in combination with daptomycin in 58% (7/12) and 42% (5/12) of patients, respectively. T 91825 30-41 solute carrier family 9 member A6 Homo sapiens 20-24 34201722-10 2021 The use of ceftaroline for MRSA-BSI, either as a monotherapy or in combination with other anti-MRSA agents, showed promising rates of favorable response. T 91825 11-22 solute carrier family 9 member A6 Homo sapiens 27-31 34201722-10 2021 The use of ceftaroline for MRSA-BSI, either as a monotherapy or in combination with other anti-MRSA agents, showed promising rates of favorable response. T 91825 11-22 solute carrier family 9 member A6 Homo sapiens 95-99 34150881-1 2021 Spread of livestock-associated methicillin resistant Staphylococcus aureus (LA-MRSA) to farmworkers has been recognized as a risk when working in LA-MRSA positive stables, due to LA-MRSA being present on airborne dust particles. Methicillin 31-42 solute carrier family 9 member A6 Homo sapiens 149-153 34150881-1 2021 Spread of livestock-associated methicillin resistant Staphylococcus aureus (LA-MRSA) to farmworkers has been recognized as a risk when working in LA-MRSA positive stables, due to LA-MRSA being present on airborne dust particles. Methicillin 31-42 solute carrier family 9 member A6 Homo sapiens 182-186 35378374-6 2022 Therefore, we hypothesized that ketamine lowers the endosomal pH by reducing the endosomal NHE6 protein level, and this hyperacidification promotes the amyloidogenic pathway. Ketamine 32-40 solute carrier family 9 member A6 Homo sapiens 91-95 35624517-0 2022 Synthesis of new 2-(5-(5-nitrofuran-2-yl)-1,3,4-thiadiazol-2-ylimino)thiazolidin-4-one derivatives as anti-MRSA and anti-H. pylori agents. 2-(5-(5-nitrofuran-2-yl)-1,3,4-thiadiazol-2-ylimino)thiazolidin-4-one 17-86 solute carrier family 9 member A6 Homo sapiens 107-111 35378374-8 2022 Western blotting results showed that 100 mg/kg ketamine treatment in vivo and 1000 muM ketamine treatment in vitro increased endosomal BACE1 and CTF-beta protein levels and reduced endosomal NHE6 and APP protein levels. Ketamine 47-55 solute carrier family 9 member A6 Homo sapiens 191-195 35378374-8 2022 Western blotting results showed that 100 mg/kg ketamine treatment in vivo and 1000 muM ketamine treatment in vitro increased endosomal BACE1 and CTF-beta protein levels and reduced endosomal NHE6 and APP protein levels. Ketamine 87-95 solute carrier family 9 member A6 Homo sapiens 191-195 35378374-12 2022 Monensin did not affect amyloidogenic-related proteins or NHE6 directly; therefore, ketamine-promoted endosomal amyloidogenic processing and BACE1 accumulation were depleted by restoring endosomal acidity through monensin pretreatment. Ketamine 84-92 solute carrier family 9 member A6 Homo sapiens 58-62 35378374-13 2022 Finally, knockdown of NHE6 promoted the amyloidogenic pathway similarly and prevented further enhancement by ketamine. Ketamine 109-117 solute carrier family 9 member A6 Homo sapiens 22-26 35378374-14 2022 These results indicated that the effects of ketamine on the amyloidogenic pathway were dependent on the reduction of NHE6 and endosomal pH. Ketamine 44-52 solute carrier family 9 member A6 Homo sapiens 117-121 3266621-1 1988 Methicillin and gentamicin resistant strains of Staphylococcus aureus (MRSA) remains a cause of significant morbidity and mortality. Methicillin 0-11 solute carrier family 9 member A6 Homo sapiens 71-75 35198730-6 2022 Results: The missense variation (c.265T>C, p.Trp89Arg) in SLC9A6 cosegregated with atypical parkinsonism and intellectual disability in female carriers of this family. trp89arg 45-53 solute carrier family 9 member A6 Homo sapiens 58-64 2687368-5 1989 For patients infected with MRSA, vancomycin is the drug of choice. Vancomycin 33-43 solute carrier family 9 member A6 Homo sapiens 27-31 35007085-0 2022 Secondary Amine Pendant beta-Peptide Polymers Displaying Potent Antibacterial Activity and Promising Therapeutic Potential in Treating MRSA-Induced Wound Infections and Keratitis. amine pendant beta-peptide polymers 10-45 solute carrier family 9 member A6 Homo sapiens 135-139 35007085-7 2022 The optimal polymer displays potent activity against antibiotic-resistant bacteria and high therapeutic efficacy in treating MRSA-induced wound infections and keratitis as well as low acute dermal toxicity and low corneal epithelial cytotoxicity. Polymers 12-19 solute carrier family 9 member A6 Homo sapiens 125-129 3266621-1 1988 Methicillin and gentamicin resistant strains of Staphylococcus aureus (MRSA) remains a cause of significant morbidity and mortality. Gentamicins 16-26 solute carrier family 9 member A6 Homo sapiens 71-75 3266621-7 1988 We believe that our data support the use of trimethoprim-sulphamethoxazole as a potentially economical and effective alternative for the treatment of infections caused by MRSA. Trimethoprim, Sulfamethoxazole Drug Combination 44-74 solute carrier family 9 member A6 Homo sapiens 171-175 33663553-2 2021 We recently found that NHE6 directly interacts with secretory carrier membrane protein 5 (SCAMP5), and SCAMP5-dependent recruitment of NHE6 to SVs controls the strength of synaptic transmission by modulation of quantal size of glutamate release at rest. Glutamic Acid 227-236 solute carrier family 9 member A6 Homo sapiens 23-27 2871075-1 1986 An outbreak of gentamicin-methicillin-resistant Staphylococcus aureus (gentamicin-resistant MRSA) which occurred during 1983-84 at the Whittington Hospital, London, is described. Gentamicins 15-25 solute carrier family 9 member A6 Homo sapiens 92-96 2871075-1 1986 An outbreak of gentamicin-methicillin-resistant Staphylococcus aureus (gentamicin-resistant MRSA) which occurred during 1983-84 at the Whittington Hospital, London, is described. Gentamicins 71-81 solute carrier family 9 member A6 Homo sapiens 92-96 2871075-4 1986 Six members of staff and one patient were colonized with gentamicin-resistant MRSA. Gentamicins 57-67 solute carrier family 9 member A6 Homo sapiens 78-82 2871075-6 1986 Seventeen patients and staff were treated with this agent and all were cleared of the original gentamicin-resistant MRSA. Gentamicins 95-105 solute carrier family 9 member A6 Homo sapiens 116-120 2871075-8 1986 Sporadic cases of gentamicin-resistant MRSA still occur at infrequent intervals. Gentamicins 18-28 solute carrier family 9 member A6 Homo sapiens 39-43 33754480-0 2021 Designing a leucine-rich antibacterial nonapeptide with potent activity against mupirocin-resistant MRSA via a structure-activity relationship study. Leucine 12-19 solute carrier family 9 member A6 Homo sapiens 100-104 33754480-0 2021 Designing a leucine-rich antibacterial nonapeptide with potent activity against mupirocin-resistant MRSA via a structure-activity relationship study. Mupirocin 80-89 solute carrier family 9 member A6 Homo sapiens 100-104 33754480-2 2021 Of particular concern is the methicillin-resistant variety, commonly known as MRSA. Methicillin 29-40 solute carrier family 9 member A6 Homo sapiens 78-82 33754480-4 2021 In this work, we describe how we designed a novel cationic nonapeptide, containing only leucine and two lysine residues, with potent anti-MRSA activity and a rapid bactericidal mode of action. Leucine 88-95 solute carrier family 9 member A6 Homo sapiens 138-142 33754480-4 2021 In this work, we describe how we designed a novel cationic nonapeptide, containing only leucine and two lysine residues, with potent anti-MRSA activity and a rapid bactericidal mode of action. Lysine 104-110 solute carrier family 9 member A6 Homo sapiens 138-142 34025612-1 2021 Methicillin-resistant Staphylococcus aureus (MRSA) belonging to clonal complex 361 (CC361-MRSA) is rare among patients" populations globally. Methicillin 0-11 solute carrier family 9 member A6 Homo sapiens 45-49 33663553-2 2021 We recently found that NHE6 directly interacts with secretory carrier membrane protein 5 (SCAMP5), and SCAMP5-dependent recruitment of NHE6 to SVs controls the strength of synaptic transmission by modulation of quantal size of glutamate release at rest. Glutamic Acid 227-236 solute carrier family 9 member A6 Homo sapiens 135-139 33663553-4 2021 Here, we found that the number of NHE6-positive presynaptic boutons was significantly increased by the chemical long-term potentiation (cLTP). cltp 136-140 solute carrier family 9 member A6 Homo sapiens 34-38 33663553-5 2021 Since cLTP involves new synapse formation, our results indicated that NHE6 was recruited not only to the existing presynaptic boutons but also to the newly formed presynaptic boutons. cltp 6-10 solute carrier family 9 member A6 Homo sapiens 70-74 33663553-6 2021 Knock down of SCAMP5 completely abrogated the enhancement of NHE6 recruitment by cLTP. cltp 81-85 solute carrier family 9 member A6 Homo sapiens 61-65 33663553-7 2021 Interestingly, despite an increase in the number of NHE6-positive boutons by cLTP, the quantal size of glutamate release at the presynaptic terminals remained unaltered. cltp 77-81 solute carrier family 9 member A6 Homo sapiens 52-56 33608606-0 2021 Association between fluoroquinolone resistance and MRSA genotype in Alexandria, Egypt. Fluoroquinolones 20-35 solute carrier family 9 member A6 Homo sapiens 51-55 33551346-6 2021 The aspirated fluid was sent for culture and sensitivity that revealed MRSA sensitive to vancomycin and linezolid. Vancomycin 89-99 solute carrier family 9 member A6 Homo sapiens 71-75 33551346-6 2021 The aspirated fluid was sent for culture and sensitivity that revealed MRSA sensitive to vancomycin and linezolid. Linezolid 104-113 solute carrier family 9 member A6 Homo sapiens 71-75 33496582-3 2021 The anti-bacterial and cell cytotoxic activity of the compounds were compared to the potent anti-MRSA compound rubrolide A; hydration across the C-5/C-6 bond was shown to abrogate antibacterial activity. rubrolide A 111-122 solute carrier family 9 member A6 Homo sapiens 97-101 33608606-12 2021 We recommend caution in treating MRSA infections with moxifloxacin. Moxifloxacin 54-66 solute carrier family 9 member A6 Homo sapiens 33-37 33372133-5 2021 The use of optical imaging and electrophysiological recording showed that small hairpin RNA-mediated knockdown (KD) of SCAMP5 or perturbation of SCAMP5/NHE6 interaction markedly inhibited axonal trafficking and the presynaptic localization of NHE6, leading to hyperacidification of SVs and a reduction in the quantal size of glutamate release. Glutamic Acid 325-334 solute carrier family 9 member A6 Homo sapiens 152-156 33057715-0 2021 Identification of a novel tedizolid resistance mutation in rpoB of MRSA after in vitro serial passage. tedizolid 26-35 solute carrier family 9 member A6 Homo sapiens 67-71 33057715-1 2021 OBJECTIVES: Tedizolid is an oxazolidinone antimicrobial with activity against Gram-positive bacteria, including MRSA. tedizolid 12-21 solute carrier family 9 member A6 Homo sapiens 112-116 33057715-1 2021 OBJECTIVES: Tedizolid is an oxazolidinone antimicrobial with activity against Gram-positive bacteria, including MRSA. Oxazolidinones 28-41 solute carrier family 9 member A6 Homo sapiens 112-116 33057715-3 2021 The objective of this study was to further explore the phenotypic and genetic basis of tedizolid resistance in MRSA. tedizolid 87-96 solute carrier family 9 member A6 Homo sapiens 111-115 33057715-4 2021 METHODS: We selected for tedizolid resistance in an MRSA laboratory strain, N315, by serial passage until an isolate with an MIC >=1 log2 dilution above the breakpoint for resistance (>=2 mg/L) was recovered. tedizolid 25-34 solute carrier family 9 member A6 Homo sapiens 52-56 33057715-4 2021 METHODS: We selected for tedizolid resistance in an MRSA laboratory strain, N315, by serial passage until an isolate with an MIC >=1 log2 dilution above the breakpoint for resistance (>=2 mg/L) was recovered. 2-Fluoro-6-methylnicotinonitrile 76-80 solute carrier family 9 member A6 Homo sapiens 52-56 31993042-0 2019 Linezolid and Rifampicin Combination to Combat cfr-Positive Multidrug-Resistant MRSA in Murine Models of Bacteremia and Skin and Skin Structure Infection. linezolid 0-9 solute carrier family 9 member A6 Homo sapiens 80-84 32891858-0 2020 Design and synthesis of novel desfluoroquinolone-aminopyrimidine hybrids as potent anti-MRSA agents with low hERG activity. desfluoroquinolone 30-48 solute carrier family 9 member A6 Homo sapiens 88-92 32891858-0 2020 Design and synthesis of novel desfluoroquinolone-aminopyrimidine hybrids as potent anti-MRSA agents with low hERG activity. 2-aminopyrimidine 49-64 solute carrier family 9 member A6 Homo sapiens 88-92 32449440-7 2020 Tedizolid exhibits antibacterial activity against the most important ABSSSI pathogens (including multidrug resistant strains of MRSA), as well as mycobacteria and Nocardia. tedizolid 0-9 solute carrier family 9 member A6 Homo sapiens 128-132 32016379-0 2020 Occurrence of cross-resistance and beta-lactam seesaw effect in glycopeptide-, lipopeptide- and lipoglycopeptide-resistant MRSA correlates with membrane phosphatidylglycerol levels. beta-Lactams 35-46 solute carrier family 9 member A6 Homo sapiens 123-127 32016379-0 2020 Occurrence of cross-resistance and beta-lactam seesaw effect in glycopeptide-, lipopeptide- and lipoglycopeptide-resistant MRSA correlates with membrane phosphatidylglycerol levels. Phosphatidylglycerols 153-173 solute carrier family 9 member A6 Homo sapiens 123-127 32016379-2 2020 Cross-resistance among these antibiotics in MRSA is well documented, as is the observation that susceptibility of MRSA to beta-lactams increases as susceptibility to GPs and LPs decreases (i.e. the seesaw effect). beta-Lactams 122-134 solute carrier family 9 member A6 Homo sapiens 44-48 32016379-2 2020 Cross-resistance among these antibiotics in MRSA is well documented, as is the observation that susceptibility of MRSA to beta-lactams increases as susceptibility to GPs and LPs decreases (i.e. the seesaw effect). beta-Lactams 122-134 solute carrier family 9 member A6 Homo sapiens 114-118 31859331-0 2020 Platinum ions mediate the interactions between DNA and carbon quantum dots: diagnosis of MRSA infections. Platinum 0-8 solute carrier family 9 member A6 Homo sapiens 89-93 31859331-0 2020 Platinum ions mediate the interactions between DNA and carbon quantum dots: diagnosis of MRSA infections. Carbon 55-61 solute carrier family 9 member A6 Homo sapiens 89-93 31859331-1 2020 In this study, we have developed a rapid and cost-effective method employing platinum ion (Pt4+)-capped fluorescent carbon quantum dots (CQDs) coupled with loop-mediated isothermal amplification (LAMP) to detect dual MRSA genes. Platinum 77-85 solute carrier family 9 member A6 Homo sapiens 217-221 31859331-1 2020 In this study, we have developed a rapid and cost-effective method employing platinum ion (Pt4+)-capped fluorescent carbon quantum dots (CQDs) coupled with loop-mediated isothermal amplification (LAMP) to detect dual MRSA genes. Platinum 91-95 solute carrier family 9 member A6 Homo sapiens 217-221 31859331-1 2020 In this study, we have developed a rapid and cost-effective method employing platinum ion (Pt4+)-capped fluorescent carbon quantum dots (CQDs) coupled with loop-mediated isothermal amplification (LAMP) to detect dual MRSA genes. Carbon 116-122 solute carrier family 9 member A6 Homo sapiens 217-221 31859331-3 2020 The CQDSPDs capped with Pt4+ ions through the cooperative coordination of the amine and chlorine groups on the surface of CQDs facilitated the double-stranded DNA (dsDNA)-induced fluorescence quenching of CQDs, and enabled the construction of the CQDSPDs/Pt4+ probe for the detection of as few as 10 copies of the MRSA gene (mecA and femA). Platinum 24-28 solute carrier family 9 member A6 Homo sapiens 314-318 31859331-3 2020 The CQDSPDs capped with Pt4+ ions through the cooperative coordination of the amine and chlorine groups on the surface of CQDs facilitated the double-stranded DNA (dsDNA)-induced fluorescence quenching of CQDs, and enabled the construction of the CQDSPDs/Pt4+ probe for the detection of as few as 10 copies of the MRSA gene (mecA and femA). Amines 78-83 solute carrier family 9 member A6 Homo sapiens 314-318 31859331-3 2020 The CQDSPDs capped with Pt4+ ions through the cooperative coordination of the amine and chlorine groups on the surface of CQDs facilitated the double-stranded DNA (dsDNA)-induced fluorescence quenching of CQDs, and enabled the construction of the CQDSPDs/Pt4+ probe for the detection of as few as 10 copies of the MRSA gene (mecA and femA). Chlorine 88-96 solute carrier family 9 member A6 Homo sapiens 314-318 31859331-3 2020 The CQDSPDs capped with Pt4+ ions through the cooperative coordination of the amine and chlorine groups on the surface of CQDs facilitated the double-stranded DNA (dsDNA)-induced fluorescence quenching of CQDs, and enabled the construction of the CQDSPDs/Pt4+ probe for the detection of as few as 10 copies of the MRSA gene (mecA and femA). Platinum 255-259 solute carrier family 9 member A6 Homo sapiens 314-318 31859331-4 2020 The sensitivity and specificity of the CQDSPDs/Pt4+ probe for MRSA detection in clinical specimens (n = 24) were 94% and 86%, respectively. Platinum 47-51 solute carrier family 9 member A6 Homo sapiens 62-66 32123664-8 2020 The patient was treated with two weeks of IV ceftriaxone and was discharged with plans to complete a six-week course of IV daptomycin due to MRSA bacteremia. Daptomycin 123-133 solute carrier family 9 member A6 Homo sapiens 141-145 33325700-0 2020 Discovery of a Potent Adenine-Benzyltriazolo-Pleuromutilin Conjugate with Pronounced Antibacterial Activity against MRSA. Adenine 22-29 solute carrier family 9 member A6 Homo sapiens 116-120 33325700-0 2020 Discovery of a Potent Adenine-Benzyltriazolo-Pleuromutilin Conjugate with Pronounced Antibacterial Activity against MRSA. benzyltriazolo-pleuromutilin 30-58 solute carrier family 9 member A6 Homo sapiens 116-120 33026882-5 2020 Through systematic analysis, we found that herbal extracts combined with antibiotics, such as beta-lactams, quinolones, aminoglycosides, tetracyclines and glycopeptides, could greatly enhance the antibacterial effects of the antibiotics, reduce the dosage and toxic side effects, and reverse MRSA resistance. beta-Lactams 94-106 solute carrier family 9 member A6 Homo sapiens 292-296 33026882-5 2020 Through systematic analysis, we found that herbal extracts combined with antibiotics, such as beta-lactams, quinolones, aminoglycosides, tetracyclines and glycopeptides, could greatly enhance the antibacterial effects of the antibiotics, reduce the dosage and toxic side effects, and reverse MRSA resistance. Quinolones 108-118 solute carrier family 9 member A6 Homo sapiens 292-296 33026882-5 2020 Through systematic analysis, we found that herbal extracts combined with antibiotics, such as beta-lactams, quinolones, aminoglycosides, tetracyclines and glycopeptides, could greatly enhance the antibacterial effects of the antibiotics, reduce the dosage and toxic side effects, and reverse MRSA resistance. Aminoglycosides 120-135 solute carrier family 9 member A6 Homo sapiens 292-296 33026882-5 2020 Through systematic analysis, we found that herbal extracts combined with antibiotics, such as beta-lactams, quinolones, aminoglycosides, tetracyclines and glycopeptides, could greatly enhance the antibacterial effects of the antibiotics, reduce the dosage and toxic side effects, and reverse MRSA resistance. Tetracyclines 137-150 solute carrier family 9 member A6 Homo sapiens 292-296 33026882-5 2020 Through systematic analysis, we found that herbal extracts combined with antibiotics, such as beta-lactams, quinolones, aminoglycosides, tetracyclines and glycopeptides, could greatly enhance the antibacterial effects of the antibiotics, reduce the dosage and toxic side effects, and reverse MRSA resistance. Glycopeptides 155-168 solute carrier family 9 member A6 Homo sapiens 292-296 32542310-11 2020 Delafloxacin was active against 94% of MRSA blood isolates that were genotype SCC IVa. delafloxacin 0-12 solute carrier family 9 member A6 Homo sapiens 39-43 32542310-13 2020 CONCLUSIONS: Delafloxacin demonstrates superior activity to levofloxacin against recent MRSA blood isolates, VISA, VRSA and DNSSA, and demonstrates good activity against blood isolates most commonly found in the community. delafloxacin 13-25 solute carrier family 9 member A6 Homo sapiens 88-92 32279050-0 2020 Synthesis of novel monocarbonyl curcuminoids, evaluation of their efficacy against MRSA, including ex vivo infection model and their mechanistic studies. Diarylheptanoids 32-44 solute carrier family 9 member A6 Homo sapiens 83-87 32279050-7 2020 Therefore, the present study affords us water-soluble, stable, non-toxic curcuminoids that may serve as lead molecules for development as antibacterial agents against MRSA infections. Water 40-45 solute carrier family 9 member A6 Homo sapiens 167-171 32279050-7 2020 Therefore, the present study affords us water-soluble, stable, non-toxic curcuminoids that may serve as lead molecules for development as antibacterial agents against MRSA infections. Diarylheptanoids 73-85 solute carrier family 9 member A6 Homo sapiens 167-171 32392437-3 2020 Objective: To assess colonization rates and changes in colonization patterns of methicillin-resistant or methicillin-sensitive Staphylococcus aureus (MRSA/MSSA) in nasal flora in patients undergoing nasal surgery and to determine whether colonization is a risk factor for postoperative infection. Methicillin 80-91 solute carrier family 9 member A6 Homo sapiens 150-154 32392437-3 2020 Objective: To assess colonization rates and changes in colonization patterns of methicillin-resistant or methicillin-sensitive Staphylococcus aureus (MRSA/MSSA) in nasal flora in patients undergoing nasal surgery and to determine whether colonization is a risk factor for postoperative infection. Methicillin 105-116 solute carrier family 9 member A6 Homo sapiens 150-154 31993042-0 2019 Linezolid and Rifampicin Combination to Combat cfr-Positive Multidrug-Resistant MRSA in Murine Models of Bacteremia and Skin and Skin Structure Infection. Rifampin 14-24 solute carrier family 9 member A6 Homo sapiens 80-84 31993042-1 2019 Linezolid resistance mediated by the cfr gene in MRSA represents a global concern. linezolid 0-9 solute carrier family 9 member A6 Homo sapiens 49-53 31993042-5 2019 In vitro phenotypes of cfr-positive MRSA translated into poor outcomes of linezolid monotherapy in vivo in murine bacteremia and SSSI models. linezolid 74-83 solute carrier family 9 member A6 Homo sapiens 36-40 31993042-8 2019 Altogether, these data suggest that the use of linezolid in combination with rifampicin poses a viable therapeutic alternative for bacteremia and SSSI caused by cfr-positive multidrug resistant MRSA. linezolid 47-56 solute carrier family 9 member A6 Homo sapiens 194-198 31993042-8 2019 Altogether, these data suggest that the use of linezolid in combination with rifampicin poses a viable therapeutic alternative for bacteremia and SSSI caused by cfr-positive multidrug resistant MRSA. Rifampin 77-87 solute carrier family 9 member A6 Homo sapiens 194-198 32047717-1 2019 Background: Isolation precautions used in methicillin-resistant Staph ylo coc cus aureus (MRSA) infection control are effective in inhibiting pathogen transmission, but may cause unintended consequences in medical care. Methicillin 42-53 solute carrier family 9 member A6 Homo sapiens 90-94 31523763-1 2020 Traditional antimicrobial susceptibility test methods for detection of S. aureus resistant to oxacillin (MRSA) such as disk diffusion, broth microdilution, and oxacillin screen plate require 18-24 h of incubation after having the organism growing in pure culture. Oxacillin 94-103 solute carrier family 9 member A6 Homo sapiens 105-109 31523763-1 2020 Traditional antimicrobial susceptibility test methods for detection of S. aureus resistant to oxacillin (MRSA) such as disk diffusion, broth microdilution, and oxacillin screen plate require 18-24 h of incubation after having the organism growing in pure culture. Oxacillin 160-169 solute carrier family 9 member A6 Homo sapiens 105-109 31676550-0 2019 Functional Assessment In Vivo of the Mouse Homolog of the Human Ala-9-Ser NHE6 Variant. ala-9-ser 64-73 solute carrier family 9 member A6 Homo sapiens 74-78 31377954-1 2019 To review the epidemiology and measures to control meticillin-resistant Staphylococcus aureus, MRSA, in Stockholm between 2000 and 2016 from the perspective of the Department of Communicable Disease Control and Prevention, Stockholm County Council, Sweden. Methicillin 51-61 solute carrier family 9 member A6 Homo sapiens 95-99 30753447-1 2019 Background: Information on outcomes of methicillin-susceptible and -resistant S. aureus (MSSA and MRSA, respectively) bacteremia, particularly readmission is scarce, and require further research to inform optimal patient care. Methicillin 39-50 solute carrier family 9 member A6 Homo sapiens 98-102 31728264-0 2019 Potential savings through single-dose intravenous Dalbavancin in long-term MRSA infection treatment - a health economic analysis using German DRG data. dalbavancin 50-61 solute carrier family 9 member A6 Homo sapiens 75-79 31505641-9 2019 MRSA were most susceptible to ceftobiprole, linezolid and telavancin (100%), daptomycin (99.9%), vancomycin (99.8%) and tigecycline (99.2%). ceftobiprole 30-42 solute carrier family 9 member A6 Homo sapiens 0-4 31175985-0 2019 A Christianson syndrome-linked deletion mutation (Delta287ES288) in SLC9A6 impairs hippocampal neuronal plasticity. delta287es288 50-63 solute carrier family 9 member A6 Homo sapiens 68-74 31505641-9 2019 MRSA were most susceptible to ceftobiprole, linezolid and telavancin (100%), daptomycin (99.9%), vancomycin (99.8%) and tigecycline (99.2%). Linezolid 44-53 solute carrier family 9 member A6 Homo sapiens 0-4 31505641-9 2019 MRSA were most susceptible to ceftobiprole, linezolid and telavancin (100%), daptomycin (99.9%), vancomycin (99.8%) and tigecycline (99.2%). telavancin 58-68 solute carrier family 9 member A6 Homo sapiens 0-4 31505641-9 2019 MRSA were most susceptible to ceftobiprole, linezolid and telavancin (100%), daptomycin (99.9%), vancomycin (99.8%) and tigecycline (99.2%). Daptomycin 77-87 solute carrier family 9 member A6 Homo sapiens 0-4 31505641-9 2019 MRSA were most susceptible to ceftobiprole, linezolid and telavancin (100%), daptomycin (99.9%), vancomycin (99.8%) and tigecycline (99.2%). Vancomycin 97-107 solute carrier family 9 member A6 Homo sapiens 0-4 31505641-9 2019 MRSA were most susceptible to ceftobiprole, linezolid and telavancin (100%), daptomycin (99.9%), vancomycin (99.8%) and tigecycline (99.2%). Tigecycline 120-131 solute carrier family 9 member A6 Homo sapiens 0-4 30994105-1 2019 IntroductionMeticillin-resistant Staphylococcus aureus (MRSA) is a major cause of healthcare-associated infections.AimWe describe MRSA colonisation/infection and bacteraemia rate trends in Dutch-German border region hospitals (NL-DE-BRH) in 2012-16.MethodsAll 42 NL-DE BRH (8 NL-BRH, 34 DE-BRH) within the cross-border network EurSafety Health-net provided surveillance data (on average ca 620,000 annual hospital admissions, of these 68.0% in Germany). introductionmeticillin 0-22 solute carrier family 9 member A6 Homo sapiens 56-60 30726929-0 2019 Genomic characterization of inpatient evolution of MRSA resistant to daptomycin, vancomycin and ceftaroline. Daptomycin 69-79 solute carrier family 9 member A6 Homo sapiens 51-55 30726929-0 2019 Genomic characterization of inpatient evolution of MRSA resistant to daptomycin, vancomycin and ceftaroline. Vancomycin 81-91 solute carrier family 9 member A6 Homo sapiens 51-55 30726929-0 2019 Genomic characterization of inpatient evolution of MRSA resistant to daptomycin, vancomycin and ceftaroline. T 91825 96-107 solute carrier family 9 member A6 Homo sapiens 51-55 30825723-0 2019 Synthesis and biological evaluation of 7-substituted cycloberberine derivatives as potent antibacterial agents against MRSA. 7-substituted cycloberberine 39-67 solute carrier family 9 member A6 Homo sapiens 119-123 30994105-1 2019 IntroductionMeticillin-resistant Staphylococcus aureus (MRSA) is a major cause of healthcare-associated infections.AimWe describe MRSA colonisation/infection and bacteraemia rate trends in Dutch-German border region hospitals (NL-DE-BRH) in 2012-16.MethodsAll 42 NL-DE BRH (8 NL-BRH, 34 DE-BRH) within the cross-border network EurSafety Health-net provided surveillance data (on average ca 620,000 annual hospital admissions, of these 68.0% in Germany). introductionmeticillin 0-22 solute carrier family 9 member A6 Homo sapiens 130-134 29890954-1 2018 BACKGROUND: Consideration to add empiric MRSA therapy with vancomycin is a common clinical dilemma. Vancomycin 59-69 solute carrier family 9 member A6 Homo sapiens 41-45 30103288-0 2019 Designing an ultra-short antibacterial peptide with potent activity against Mupirocin-resistant MRSA. Mupirocin 76-85 solute carrier family 9 member A6 Homo sapiens 96-100 30103288-2 2019 In particular, the methicillin-resistant variety, MRSA, has become a global clinical concern. Methicillin 19-30 solute carrier family 9 member A6 Homo sapiens 50-54 30103288-3 2019 The extensive use of mupirocin, the first-line topical antibacterial drug of choice, has led to the emergence of mupirocin-resistant MRSA globally, resulting in the urgent need for a replacement. Mupirocin 21-30 solute carrier family 9 member A6 Homo sapiens 133-137 30103288-3 2019 The extensive use of mupirocin, the first-line topical antibacterial drug of choice, has led to the emergence of mupirocin-resistant MRSA globally, resulting in the urgent need for a replacement. Mupirocin 113-122 solute carrier family 9 member A6 Homo sapiens 133-137 30316060-1 2018 The design, synthesis and evaluation of a small series of potent amphiphilic norbornane antibacterial agents has been performed (compound 10 MIC = 0.25 mug/mL against MRSA). Norbornanes 77-87 solute carrier family 9 member A6 Homo sapiens 167-171 30316060-3 2018 Two fluorescent analogues (compound 29 with 4-amino-naphthalimide and 34 with 4-nitrobenz-2-oxa-1,3-diazole fluorophores) with good activity (MIC = 0.5 mug/mL against MRSA) were also constructed and confocal microscopy studies indicate that the primary site of interaction for this family of compounds is the bacterial membrane. 4-nitrobenz-2-oxa-1,3-diazole fluorophores 78-120 solute carrier family 9 member A6 Homo sapiens 167-171 31192222-10 2019 In postmortem brains from the ROS/MAP dataset of normal and pathological aging, decreased NHE6 expression was correlated with greater tau deposition. ros 30-33 solute carrier family 9 member A6 Homo sapiens 90-94 30535122-11 2019 Standard linezolid dosing in obese pneumonia patients with MRSA (MICs of 1-4 mg/L) leads to unacceptably low (near zero to 60%) PTA for patients <65 years old. Linezolid 9-18 solute carrier family 9 member A6 Homo sapiens 59-63 30535122-13 2019 Body weight and especially age are important characteristics to be considered when administering linezolid to treat MRSA infections. Linezolid 97-106 solute carrier family 9 member A6 Homo sapiens 116-120 30230671-0 2018 Transcript Profiling of MRSA Biofilms Treated with a Halogenated Phenazine Eradicating Agent: A Platform for Defining Cellular Targets and Pathways Critical to Biofilm Survival. phenazine 65-74 solute carrier family 9 member A6 Homo sapiens 24-28 30230671-4 2018 WoPPER analysis with time-course validation (RT-qPCR) revealed that HP-14 induces rapid iron starvation in MRSA biofilms, as evident by the activation of iron-acquisition gene clusters in 1 hour. Iron 88-92 solute carrier family 9 member A6 Homo sapiens 107-111 30230671-4 2018 WoPPER analysis with time-course validation (RT-qPCR) revealed that HP-14 induces rapid iron starvation in MRSA biofilms, as evident by the activation of iron-acquisition gene clusters in 1 hour. Iron 154-158 solute carrier family 9 member A6 Homo sapiens 107-111 30230671-7 2018 These findings suggest that MRSA biofilm viability relies on iron homeostasis. Iron 61-65 solute carrier family 9 member A6 Homo sapiens 28-32 29755606-7 2018 We detected a high resistance rate to common antibiotics, e.g. 83% of S. aureus isolates were resistant to oxacillin (MRSA). Oxacillin 107-116 solute carrier family 9 member A6 Homo sapiens 118-122 29777150-0 2018 Risk factors of treatment failure and 30-day mortality in patients with bacteremia due to MRSA with reduced vancomycin susceptibility. Vancomycin 108-118 solute carrier family 9 member A6 Homo sapiens 90-94 29777150-1 2018 Bacteremia caused by MRSA with reduced vancomycin susceptibility (MRSA-RVS) frequently resulted in treatment failure and mortality. Vancomycin 39-49 solute carrier family 9 member A6 Homo sapiens 21-25 29777150-1 2018 Bacteremia caused by MRSA with reduced vancomycin susceptibility (MRSA-RVS) frequently resulted in treatment failure and mortality. Vancomycin 39-49 solute carrier family 9 member A6 Homo sapiens 66-70 29777150-3 2018 We retrospectively reviewed clinical data of patients with bacteremia caused by MRSA with vancomycin MIC = 2 mg/L from 2009 to 2012. Vancomycin 90-100 solute carrier family 9 member A6 Homo sapiens 80-84 29244141-4 2018 Patients and methods: This was a retrospective study of hospitalized patients at two tertiary care academic medical centres with recurrent or persistent (>=3 days) MRSA-B treated with telavancin monotherapy. telavancin 187-197 solute carrier family 9 member A6 Homo sapiens 167-171 30250892-2 2018 We recently identified a conceptually novel mechanism for how dysregulated pH in hypoxic cells causes chemoresistance which is based on the aberrant cellular distribution of the endosomal pH regulator, the sodium/hydrogen exchanger 6 (NHE6). Sodium 206-212 solute carrier family 9 member A6 Homo sapiens 235-239 30250892-2 2018 We recently identified a conceptually novel mechanism for how dysregulated pH in hypoxic cells causes chemoresistance which is based on the aberrant cellular distribution of the endosomal pH regulator, the sodium/hydrogen exchanger 6 (NHE6). Hydrogen 213-221 solute carrier family 9 member A6 Homo sapiens 235-239 29244141-6 2018 Results: Telavancin dosed 10 mg/kg three times weekly post-IHD or 10 mg/kg every 48 h resulted in microbiological cure in 7/8 (87.5%) refractory MRSA-B cases. telavancin 9-19 solute carrier family 9 member A6 Homo sapiens 145-149 29244141-9 2018 Conclusions: Telavancin was very safe and highly effective in the treatment of refractory MRSA-B in a cohort of patients with ESRD requiring IHD. telavancin 13-23 solute carrier family 9 member A6 Homo sapiens 90-94 28962026-0 2017 Pharmacodynamics of teicoplanin against MRSA. Teicoplanin 20-31 solute carrier family 9 member A6 Homo sapiens 40-44 29258622-6 2017 MRSA was detected using both Cefoxitin (30 mug) and Oxacillin (6 mug) (Oxoid Ltd. England) discs in combination and associated factors were assessed using self-administered pretested questionnaires, which were delivered to the children"s parents/guardians. Cefoxitin 29-38 solute carrier family 9 member A6 Homo sapiens 0-4 29258622-6 2017 MRSA was detected using both Cefoxitin (30 mug) and Oxacillin (6 mug) (Oxoid Ltd. England) discs in combination and associated factors were assessed using self-administered pretested questionnaires, which were delivered to the children"s parents/guardians. Oxacillin 52-61 solute carrier family 9 member A6 Homo sapiens 0-4 28962026-1 2017 Objectives: The overall study aim was to identify the relevant preclinical teicoplanin pharmacokinetic (PK)/pharmacodynamic (PD) indices to predict efficacy and suppression of resistance in MRSA infection. Teicoplanin 75-86 solute carrier family 9 member A6 Homo sapiens 190-194 28962026-10 2017 Conclusions: This study improves our understanding of teicoplanin PD against MRSA and defines an in vivo AUC/MIC target for efficacy and suppression of resistance. Teicoplanin 54-65 solute carrier family 9 member A6 Homo sapiens 77-81 29029278-1 2017 Background: Delafloxacin is an investigational anionic fluoroquinolone in development for oral or intravenous administration for the treatment of infections caused by Gram-positive (including MRSA), Gram-negative, atypical and anaerobic organisms. delafloxacin 12-24 solute carrier family 9 member A6 Homo sapiens 192-196 28552898-5 2017 Results indicated that the vancomycin-coated sample was biocompatible for Human osteoblast cell line MG-63 and displayed effective antibacterial ability against MRSA. Vancomycin 27-37 solute carrier family 9 member A6 Homo sapiens 161-165 29029278-9 2017 Bacterial eradication of MRSA was 100% and 98.5% in the delafloxacin group and the vancomycin/aztreonam group, respectively. delafloxacin 56-68 solute carrier family 9 member A6 Homo sapiens 25-29 29029278-9 2017 Bacterial eradication of MRSA was 100% and 98.5% in the delafloxacin group and the vancomycin/aztreonam group, respectively. Vancomycin 83-93 solute carrier family 9 member A6 Homo sapiens 25-29 29029278-9 2017 Bacterial eradication of MRSA was 100% and 98.5% in the delafloxacin group and the vancomycin/aztreonam group, respectively. Aztreonam 94-103 solute carrier family 9 member A6 Homo sapiens 25-29 28265870-6 2017 The increased consumption of amoxicillin/clavulanate and piperacillin/tazobactam was associated with the reduction of MRSA rate from 48.5 to 25.9% (p = 0.007 and p = 0.04, respectively). Amoxicillin-Potassium Clavulanate Combination 29-52 solute carrier family 9 member A6 Homo sapiens 118-122 28265870-6 2017 The increased consumption of amoxicillin/clavulanate and piperacillin/tazobactam was associated with the reduction of MRSA rate from 48.5 to 25.9% (p = 0.007 and p = 0.04, respectively). Piperacillin, Tazobactam Drug Combination 57-80 solute carrier family 9 member A6 Homo sapiens 118-122 27774857-0 2017 In-vitro activity of ceftriaxone combined with newer agents against MRSA. Ceftriaxone 21-32 solute carrier family 9 member A6 Homo sapiens 68-72 27774857-1 2017 In this study, in vitro synergism in combinations of agents as ceftriaxone/dalbavancin, ceftriaxone/linezolid and ceftriaxone/daptomycin against MRSA strains were investigated. Linezolid 100-109 solute carrier family 9 member A6 Homo sapiens 145-149 28676409-4 2017 The recommended perioperative prophylaxis was cefuroxime (or vancomycin in case of documented MRSA body carriage). Vancomycin 61-71 solute carrier family 9 member A6 Homo sapiens 94-98 28824185-6 2017 Patients with MRSA infection were additionally administered intravenous vancomycin in combination with either oral rifampicin or trimethoprim-sulfamethoxazole. Vancomycin 72-82 solute carrier family 9 member A6 Homo sapiens 14-18 28578731-0 2017 Bacterial Infections in Neonates Following Mupirocin-Based MRSA Decolonization: A Multicenter Cohort Study. Mupirocin 43-52 solute carrier family 9 member A6 Homo sapiens 59-63 28578731-1 2017 OBJECTIVE To characterize the risk of infection after MRSA decolonization with intranasal mupirocin. Mupirocin 90-99 solute carrier family 9 member A6 Homo sapiens 54-58 28578731-8 2017 Of the MRSA-colonized neonates, 384 (74%) received mupirocin. Mupirocin 51-60 solute carrier family 9 member A6 Homo sapiens 7-11 28578731-11 2017 CONCLUSIONS In this multicentered cohort of MRSA-colonized neonates, mupirocin-based decolonization treatment appeared to decrease the risk of infection with select gram-positive organisms as intended, and the treatment was not significantly associated with risk of subsequent infections with organisms not covered by mupirocin"s spectrum of activity. Mupirocin 69-78 solute carrier family 9 member A6 Homo sapiens 44-48 27999030-7 2017 MRSA and MSSA carriers were less likely than SA non-carriers to be female (50% and 56% versus 68%, P = 0.03) or to have recently used beta-lactam antibiotics (43% and 65% versus 73%, P = 0.01). beta-Lactams 135-146 solute carrier family 9 member A6 Homo sapiens 0-4 28473167-13 2017 Glycopeptide (e.g.Teicoplanin) prophylaxis should be considered when there is history of MRSA colonization or MRSA screening results are not available before the surgery. Teicoplanin 18-29 solute carrier family 9 member A6 Homo sapiens 89-93 28473167-13 2017 Glycopeptide (e.g.Teicoplanin) prophylaxis should be considered when there is history of MRSA colonization or MRSA screening results are not available before the surgery. Teicoplanin 18-29 solute carrier family 9 member A6 Homo sapiens 110-114 28343752-7 2017 In mixed infection model, tedizolid therapy showed similar antimicrobial activities for one MRSA and two P. anaerobius isolates evaluated, compared with linezolid therapy. tedizolid 26-35 solute carrier family 9 member A6 Homo sapiens 92-96 28343752-9 2017 CONCLUSION: In the neutropenic murine thigh infection model, human simulated exposures of tedizolid and linezolid resulted in similar efficacies against MRSA, even though single and mixed infection models were used. tedizolid 90-99 solute carrier family 9 member A6 Homo sapiens 153-157 28343752-9 2017 CONCLUSION: In the neutropenic murine thigh infection model, human simulated exposures of tedizolid and linezolid resulted in similar efficacies against MRSA, even though single and mixed infection models were used. Linezolid 104-113 solute carrier family 9 member A6 Homo sapiens 153-157 28473167-11 2017 Of those receiving cefuroxime, five (22.73%) patients developed postoperative MRSA surgical site infection (SSI) but none of those (0%) receiving Teicoplanin had MRSA SSI. Cefuroxime 19-29 solute carrier family 9 member A6 Homo sapiens 78-82 28343752-5 2017 RESULTS: The tedizolid and linezolid MICs for MRSA was 0.25 and 2 mug/ml. tedizolid 13-22 solute carrier family 9 member A6 Homo sapiens 46-50 28343752-5 2017 RESULTS: The tedizolid and linezolid MICs for MRSA was 0.25 and 2 mug/ml. Linezolid 27-36 solute carrier family 9 member A6 Homo sapiens 46-50 28314920-5 2017 In part, only expert opinions are given due to lack of study results.The two 5th generation cephalosporins ceftaroline and ceftobiprole have beside their equivalent efficacy to ceftriaxone (ceftaroline) and cefipim (ceftobiprole) high activity against MRSA. Cephalosporins 92-106 solute carrier family 9 member A6 Homo sapiens 252-256 28314920-5 2017 In part, only expert opinions are given due to lack of study results.The two 5th generation cephalosporins ceftaroline and ceftobiprole have beside their equivalent efficacy to ceftriaxone (ceftaroline) and cefipim (ceftobiprole) high activity against MRSA. T 91825 107-118 solute carrier family 9 member A6 Homo sapiens 252-256 28314920-5 2017 In part, only expert opinions are given due to lack of study results.The two 5th generation cephalosporins ceftaroline and ceftobiprole have beside their equivalent efficacy to ceftriaxone (ceftaroline) and cefipim (ceftobiprole) high activity against MRSA. ceftobiprole 123-135 solute carrier family 9 member A6 Homo sapiens 252-256 28314920-7 2017 The oxazolidinone tedizolid is effective against linezolid-resistant MRSA. Oxazolidinones 4-17 solute carrier family 9 member A6 Homo sapiens 69-73 28314920-7 2017 The oxazolidinone tedizolid is effective against linezolid-resistant MRSA. tedizolid 18-27 solute carrier family 9 member A6 Homo sapiens 69-73 28314920-7 2017 The oxazolidinone tedizolid is effective against linezolid-resistant MRSA. Linezolid 49-58 solute carrier family 9 member A6 Homo sapiens 69-73 28900682-7 2017 While infections caused by methicillin-susceptible S. aureus (MSSA) strains are usually treated with drugs in the ss-lactam class, such as cephalosporins, oxacillin or nafcillin, MRSA infections are treated with drugs in other antimicrobial classes. ss-lactam 114-123 solute carrier family 9 member A6 Homo sapiens 179-183 27733516-0 2017 Increasing resistance to fusidic acid among clinical isolates of MRSA. Fusidic Acid 25-37 solute carrier family 9 member A6 Homo sapiens 65-69 28900682-4 2017 These MRSA isolates, resistant to nearly all ss-lactam antimicrobials, were first largely confined to the health care environment and the patients who attended it. ss-lactam 45-54 solute carrier family 9 member A6 Homo sapiens 6-10 28900682-7 2017 While infections caused by methicillin-susceptible S. aureus (MSSA) strains are usually treated with drugs in the ss-lactam class, such as cephalosporins, oxacillin or nafcillin, MRSA infections are treated with drugs in other antimicrobial classes. Cephalosporins 139-153 solute carrier family 9 member A6 Homo sapiens 179-183 27494923-0 2016 Molecular basis of rifampicin resistance in multiresistant porcine livestock-associated MRSA. Rifampin 19-29 solute carrier family 9 member A6 Homo sapiens 88-92 28900682-6 2017 CA-MRSA organisms, compared with health care-associated (HA-) MRSA strain types, are more often susceptible to multiple classes of non ss-lactam antimicrobials. Lactams 138-144 solute carrier family 9 member A6 Homo sapiens 3-7 28900682-6 2017 CA-MRSA organisms, compared with health care-associated (HA-) MRSA strain types, are more often susceptible to multiple classes of non ss-lactam antimicrobials. Lactams 138-144 solute carrier family 9 member A6 Homo sapiens 62-66 28900682-7 2017 While infections caused by methicillin-susceptible S. aureus (MSSA) strains are usually treated with drugs in the ss-lactam class, such as cephalosporins, oxacillin or nafcillin, MRSA infections are treated with drugs in other antimicrobial classes. Methicillin 27-38 solute carrier family 9 member A6 Homo sapiens 179-183 26431268-0 2016 Role of linezolid therapeutic drug monitoring in the treatment of MRSA tracheo-pulmonary infection in a 10-month-old infant. Linezolid 8-17 solute carrier family 9 member A6 Homo sapiens 66-70 27741342-11 2016 CONCLUSION: Topical minocycline foam may be a safe and effective new treatment option for impetigo in children, including those with MRSA. Minocycline 20-31 solute carrier family 9 member A6 Homo sapiens 133-137 27590723-4 2016 METHODS: Here, we examined the molecular and cellular consequences of a 6 base-pair deletion of amino acids Glu(287) and Ser(288) ( ES) in the predicted seventh transmembrane helix of human NHE6 expressed in established cell lines (CHO/AP-1, HeLa and neuroblastoma SH-SY5Y) and primary cultures of mouse hippocampal neurons by measuring levels of protein expression, stability, membrane trafficking, endosomal function and cell viability. Glutamic Acid 108-111 solute carrier family 9 member A6 Homo sapiens 190-194 27590723-4 2016 METHODS: Here, we examined the molecular and cellular consequences of a 6 base-pair deletion of amino acids Glu(287) and Ser(288) ( ES) in the predicted seventh transmembrane helix of human NHE6 expressed in established cell lines (CHO/AP-1, HeLa and neuroblastoma SH-SY5Y) and primary cultures of mouse hippocampal neurons by measuring levels of protein expression, stability, membrane trafficking, endosomal function and cell viability. Einsteinium 132-134 solute carrier family 9 member A6 Homo sapiens 190-194 30108790-2 2017 This rapid synthesis permitted the discovery of novel biofilm-eradicating halogenated quinolines (MBECs = 1.0-23.5 muM) active against MRSA, MRSE, and VRE. Quinolines 86-96 solute carrier family 9 member A6 Homo sapiens 135-139 27347712-5 2016 EXPERT OPINION: There are several promising compounds on their way, as tedizolid-a new oxazolidone, iclaprim-a novel drug, related to trimethoprim, plazomicin-a new aminoglycoside and two combinations of ceftazidime/avibactam and ceftolozane/tazobactam against MDR bacteria, especially against MRSA and Gram-negative ESBL bacteria. tedizolid-a 71-82 solute carrier family 9 member A6 Homo sapiens 294-298 27347712-5 2016 EXPERT OPINION: There are several promising compounds on their way, as tedizolid-a new oxazolidone, iclaprim-a novel drug, related to trimethoprim, plazomicin-a new aminoglycoside and two combinations of ceftazidime/avibactam and ceftolozane/tazobactam against MDR bacteria, especially against MRSA and Gram-negative ESBL bacteria. Oxazolidinones 87-98 solute carrier family 9 member A6 Homo sapiens 294-298 27347712-5 2016 EXPERT OPINION: There are several promising compounds on their way, as tedizolid-a new oxazolidone, iclaprim-a novel drug, related to trimethoprim, plazomicin-a new aminoglycoside and two combinations of ceftazidime/avibactam and ceftolozane/tazobactam against MDR bacteria, especially against MRSA and Gram-negative ESBL bacteria. iclaprim-a 100-110 solute carrier family 9 member A6 Homo sapiens 294-298 27347712-5 2016 EXPERT OPINION: There are several promising compounds on their way, as tedizolid-a new oxazolidone, iclaprim-a novel drug, related to trimethoprim, plazomicin-a new aminoglycoside and two combinations of ceftazidime/avibactam and ceftolozane/tazobactam against MDR bacteria, especially against MRSA and Gram-negative ESBL bacteria. Trimethoprim 134-146 solute carrier family 9 member A6 Homo sapiens 294-298 27347712-5 2016 EXPERT OPINION: There are several promising compounds on their way, as tedizolid-a new oxazolidone, iclaprim-a novel drug, related to trimethoprim, plazomicin-a new aminoglycoside and two combinations of ceftazidime/avibactam and ceftolozane/tazobactam against MDR bacteria, especially against MRSA and Gram-negative ESBL bacteria. plazomicin-a 148-160 solute carrier family 9 member A6 Homo sapiens 294-298 27347712-5 2016 EXPERT OPINION: There are several promising compounds on their way, as tedizolid-a new oxazolidone, iclaprim-a novel drug, related to trimethoprim, plazomicin-a new aminoglycoside and two combinations of ceftazidime/avibactam and ceftolozane/tazobactam against MDR bacteria, especially against MRSA and Gram-negative ESBL bacteria. Aminoglycosides 165-179 solute carrier family 9 member A6 Homo sapiens 294-298 27073268-0 2016 Linezolid-resistant cfr-positive MRSA, Italy. Linezolid 0-9 solute carrier family 9 member A6 Homo sapiens 33-37 27307987-5 2016 The protocol makes use of polyhexanide-based products, in view of reported qac-mediated resistance to chlorhexidine in S. aureus and MRSA. polihexanide 26-38 solute carrier family 9 member A6 Homo sapiens 133-137 27216998-0 2016 Caged xanthones: Potent inhibitors of global predominant MRSA USA300. Xanthones 6-15 solute carrier family 9 member A6 Homo sapiens 57-61 26949849-2 2016 Following the combined use of octenilin Wound Gel and octenilin Wound Irrigation Solution, the MRSA was removed in 4 weeks, the necrotic tissue was debrided and the wound started healing. octenilin 54-63 solute carrier family 9 member A6 Homo sapiens 95-99 27154505-6 2016 PKS type-I gene detection and chromatographic strategy yielded a robust polyketide antimicrobial compound which identified as nocapyrone E. Minimum inhibitory concentration of the purified compound against MRSA and other human pathogens ranged between 25 and 100 mug/ml. nocapyrone S 126-136 solute carrier family 9 member A6 Homo sapiens 206-210 27022790-2 2016 MATERIALS AND METHODS: Nasal samples were taken from anterior nares were cultured in CHROMagar S. aureus plates, MRSA was determined by disc diffusion method (cefoxitin 30 mug) according to the Clinical and Laboratory Standards Institute guidelines and CHROMagar MRSA plates. Cefoxitin 159-168 solute carrier family 9 member A6 Homo sapiens 113-117 26899719-6 2016 The gentamicin, vancomycin, amikacin and ceftriaxone beads all inhibited growth of the MRSA on the TSB and agar plates, both before and after gas sterilisation. Gentamicins 4-14 solute carrier family 9 member A6 Homo sapiens 87-91 26899719-6 2016 The gentamicin, vancomycin, amikacin and ceftriaxone beads all inhibited growth of the MRSA on the TSB and agar plates, both before and after gas sterilisation. Vancomycin 16-26 solute carrier family 9 member A6 Homo sapiens 87-91 26899719-6 2016 The gentamicin, vancomycin, amikacin and ceftriaxone beads all inhibited growth of the MRSA on the TSB and agar plates, both before and after gas sterilisation. Amikacin 28-36 solute carrier family 9 member A6 Homo sapiens 87-91 26899719-6 2016 The gentamicin, vancomycin, amikacin and ceftriaxone beads all inhibited growth of the MRSA on the TSB and agar plates, both before and after gas sterilisation. Ceftriaxone 41-52 solute carrier family 9 member A6 Homo sapiens 87-91 26899719-6 2016 The gentamicin, vancomycin, amikacin and ceftriaxone beads all inhibited growth of the MRSA on the TSB and agar plates, both before and after gas sterilisation. Tri S Bond 99-102 solute carrier family 9 member A6 Homo sapiens 87-91 26899719-6 2016 The gentamicin, vancomycin, amikacin and ceftriaxone beads all inhibited growth of the MRSA on the TSB and agar plates, both before and after gas sterilisation. Agar 107-111 solute carrier family 9 member A6 Homo sapiens 87-91 26565015-1 2016 MRSA bacteraemia (MRSAB), including infective endocarditis, carries a high mortality rate, with up to 50% of patients failing initial therapy with vancomycin and requiring salvage therapy. Vancomycin 147-157 solute carrier family 9 member A6 Homo sapiens 0-4 26782772-0 2016 Novel adjuvant strategy to potentiate bacitracin against MDR MRSA. Bacitracin 38-48 solute carrier family 9 member A6 Homo sapiens 61-65 26782772-2 2016 However, bacitracin resistance is highly prevalent in community-associated MRSA (CA-MRSA) strains and significantly compromises the effectiveness of existing antimicrobial ointments. Bacitracin 9-19 solute carrier family 9 member A6 Homo sapiens 75-79 26782772-2 2016 However, bacitracin resistance is highly prevalent in community-associated MRSA (CA-MRSA) strains and significantly compromises the effectiveness of existing antimicrobial ointments. Bacitracin 9-19 solute carrier family 9 member A6 Homo sapiens 84-88 26782772-4 2016 METHODS: The growth of MRSA USA300, the predominant CA-MRSA strain in the USA, was determined in the presence of bacitracin and alkyl gallates at various concentrations. bacitracin and alkyl gallates 113-142 solute carrier family 9 member A6 Homo sapiens 23-27 26782772-5 2016 The viability of USA300 and MDR clinical isolates of MRSA was measured after exposure to various combinations of bacitracin and alkyl gallates. Bacitracin 113-123 solute carrier family 9 member A6 Homo sapiens 53-57 26782772-5 2016 The viability of USA300 and MDR clinical isolates of MRSA was measured after exposure to various combinations of bacitracin and alkyl gallates. alkyl gallates 128-142 solute carrier family 9 member A6 Homo sapiens 53-57 26782772-9 2016 Furthermore, bacitracin/OG combinations demonstrated similar levels of antimicrobial activity against human clinical isolates of MRSA resistant to multiple antibiotics of clinical importance. Bacitracin 13-23 solute carrier family 9 member A6 Homo sapiens 129-133 26782772-9 2016 Furthermore, bacitracin/OG combinations demonstrated similar levels of antimicrobial activity against human clinical isolates of MRSA resistant to multiple antibiotics of clinical importance. octyl gallate 24-26 solute carrier family 9 member A6 Homo sapiens 129-133 26782772-10 2016 CONCLUSIONS: Some alkyl gallates, particularly OG, significantly increased the antimicrobial activity of bacitracin against MDR MRSA. alkyl gallates 18-32 solute carrier family 9 member A6 Homo sapiens 128-132 26782772-10 2016 CONCLUSIONS: Some alkyl gallates, particularly OG, significantly increased the antimicrobial activity of bacitracin against MDR MRSA. octyl gallate 47-49 solute carrier family 9 member A6 Homo sapiens 128-132 26782772-10 2016 CONCLUSIONS: Some alkyl gallates, particularly OG, significantly increased the antimicrobial activity of bacitracin against MDR MRSA. Bacitracin 105-115 solute carrier family 9 member A6 Homo sapiens 128-132 26849655-8 2016 CONCLUSIONS: Application of the MRSA S&D policy saves lives and money, although the high rate of unexpected MRSA cases is alarming. Adenosine Monophosphate 39-42 solute carrier family 9 member A6 Homo sapiens 32-36 25764306-4 2015 Because her partner appeared to have solitary MRSA carriage on the glans, a suggestion of sexual transmission was made. glans 67-72 solute carrier family 9 member A6 Homo sapiens 46-50 27528869-5 2016 Patients carrying MSSA and MRSA were treated preoperatively with mupirocin and vancomycin, respectively, along with the standard preoperative antibiotics and chlorhexidine body wipes. Mupirocin 65-74 solute carrier family 9 member A6 Homo sapiens 27-31 27528869-5 2016 Patients carrying MSSA and MRSA were treated preoperatively with mupirocin and vancomycin, respectively, along with the standard preoperative antibiotics and chlorhexidine body wipes. Vancomycin 79-89 solute carrier family 9 member A6 Homo sapiens 27-31 26421989-0 2015 Successful Treatment of Electrographic Status Epilepticus of Sleep With Felbamate in a Patient With SLC9A6 Mutation. Felbamate 72-81 solute carrier family 9 member A6 Homo sapiens 100-106 26338047-0 2015 Impact of mupirocin resistance on the transmission and control of healthcare-associated MRSA. Mupirocin 10-19 solute carrier family 9 member A6 Homo sapiens 88-92 26338047-6 2015 The total prevalence of MupR in colonized and infected MRSA patients after 5 years of simulation was 9.1% (95% CI 8.7%-9.6%) with the "screen and treat" mupirocin policy, increasing to 21.3% (95% CI 20.9%-21.7%) with "universal" mupirocin use. Mupirocin 153-162 solute carrier family 9 member A6 Homo sapiens 55-59 26414088-0 2015 Halogenated quinolines discovered through reductive amination with potent eradication activities against MRSA, MRSE and VRE biofilms. Quinolines 12-22 solute carrier family 9 member A6 Homo sapiens 105-109 26414088-2 2015 Here, we report the discovery of several halogenated quinolines (HQs) identified through a reductive amination reaction that demonstrated potent eradication of MRSA (HQ-6; MBEC = 125 muM), MRSE (HQ-3; MBEC = 3.0 muM) and VRE (HQ-4, HQ-5 and HQ-6; MBEC = 1.0 muM) biofilms. Quinolines 53-63 solute carrier family 9 member A6 Homo sapiens 160-164 26142407-6 2015 Among MRSA isolates, the presence of the qacA and/or qacB gene, encoding resistance to chlorhexidine, ranges from 65% to 91%, which, along with mupirocin resistance, is associated with failed decolonization. Chlorhexidine 87-100 solute carrier family 9 member A6 Homo sapiens 6-10 26142407-0 2015 Mupirocin resistance: clinical implications and potential alternatives for the eradication of MRSA. Mupirocin 0-9 solute carrier family 9 member A6 Homo sapiens 94-98 26142407-6 2015 Among MRSA isolates, the presence of the qacA and/or qacB gene, encoding resistance to chlorhexidine, ranges from 65% to 91%, which, along with mupirocin resistance, is associated with failed decolonization. Mupirocin 144-153 solute carrier family 9 member A6 Homo sapiens 6-10 26142407-1 2015 Mupirocin 2% ointment is used either alone or with skin antiseptics as part of a comprehensive MRSA decolonization strategy. Mupirocin 0-9 solute carrier family 9 member A6 Homo sapiens 95-99 26142407-2 2015 Increased mupirocin use predisposes to mupirocin resistance, which is significantly associated with persistent MRSA carriage. Mupirocin 10-19 solute carrier family 9 member A6 Homo sapiens 111-115 26026664-4 2015 Segregated analysis of the results depending on the origin of the isolates (clinical, animal, and food) revealed a significant lower performance in the MRSA confirmation of food-derived isolates by using Brilliance MRSA 2 agar in comparison to PCR confirmation (p = 0.003) or ChromID MRSA agar (p<0.001). Agar 222-226 solute carrier family 9 member A6 Homo sapiens 152-156 26142407-2 2015 Increased mupirocin use predisposes to mupirocin resistance, which is significantly associated with persistent MRSA carriage. Mupirocin 39-48 solute carrier family 9 member A6 Homo sapiens 111-115 26026664-4 2015 Segregated analysis of the results depending on the origin of the isolates (clinical, animal, and food) revealed a significant lower performance in the MRSA confirmation of food-derived isolates by using Brilliance MRSA 2 agar in comparison to PCR confirmation (p = 0.003) or ChromID MRSA agar (p<0.001). Agar 222-226 solute carrier family 9 member A6 Homo sapiens 215-219 26026664-4 2015 Segregated analysis of the results depending on the origin of the isolates (clinical, animal, and food) revealed a significant lower performance in the MRSA confirmation of food-derived isolates by using Brilliance MRSA 2 agar in comparison to PCR confirmation (p = 0.003) or ChromID MRSA agar (p<0.001). Agar 222-226 solute carrier family 9 member A6 Homo sapiens 215-219 26258318-9 2015 Gram-positive related infections and MRSA infections occurred in 1(1.18%)/0(0%) of Vancomycin patients and 9 (9.68%)/1 (1.08%) of Daptomycin patients, respectively (P < 0.02 and P = 1.00). Vancomycin 83-93 solute carrier family 9 member A6 Homo sapiens 37-41 26258318-9 2015 Gram-positive related infections and MRSA infections occurred in 1(1.18%)/0(0%) of Vancomycin patients and 9 (9.68%)/1 (1.08%) of Daptomycin patients, respectively (P < 0.02 and P = 1.00). Daptomycin 130-140 solute carrier family 9 member A6 Homo sapiens 37-41 26198370-2 2015 We conducted a real-world analysis of antibiotic treatment, hospital resource use and clinical outcomes in patients with PVD and/or diabetes receiving linezolid or vancomycin for the treatment of methicillin-resistant Staphylococcus aureus complicated skin and soft-tissue infections (MRSA cSSTIs) across Europe. Linezolid 151-160 solute carrier family 9 member A6 Homo sapiens 285-289 26273719-1 2015 Total Synthesis of MRSA-Active Tetarimycin A and Its Analogues. tetarimycin A 31-44 solute carrier family 9 member A6 Homo sapiens 19-23 26273719-3 2015 Preliminary SAR not only validated that tetarimycin A exhibited potent activity against MRSA and VRE at a low MIC value but also identified that the hydroxyl group at C-10 was essential for antibacterial activities. tetarimycin A 40-53 solute carrier family 9 member A6 Homo sapiens 88-92 26198370-2 2015 We conducted a real-world analysis of antibiotic treatment, hospital resource use and clinical outcomes in patients with PVD and/or diabetes receiving linezolid or vancomycin for the treatment of methicillin-resistant Staphylococcus aureus complicated skin and soft-tissue infections (MRSA cSSTIs) across Europe. Vancomycin 164-174 solute carrier family 9 member A6 Homo sapiens 285-289 26198370-9 2015 The reduction in resource use may result in lower hospital costs for patients with PVD and/or diabetes and MRSA cSSTIs if treated with linezolid compared with vancomycin. Linezolid 135-144 solute carrier family 9 member A6 Homo sapiens 107-111 26048876-9 2015 Moreover, for the first time the qacG and qacJ genes were detected in MRSA CC398 strains. qacg 33-37 solute carrier family 9 member A6 Homo sapiens 70-74 26305895-11 2015 The drop in MRSA prevalence in people during the study could be attributed to the observed long-term AMU decreasing trend. N-acetyl-beta-muramic acid 101-104 solute carrier family 9 member A6 Homo sapiens 12-16 25904727-1 2015 OBJECTIVES: The antimicrobial efficacy of an iodine-impregnated incise drape against MRSA was evaluated in a skin model. Iodine 45-51 solute carrier family 9 member A6 Homo sapiens 85-89 25904727-7 2015 Furthermore, in experiments wherein a high inoculum of MRSA was applied with no pre-incubation period, the iodine-impregnated drape demonstrated superior antimicrobial activity compared with the use of a non-antimicrobial drape (P < 0.001). Iodine 107-113 solute carrier family 9 member A6 Homo sapiens 55-59 24313336-5 2015 Moreover, Mrs A"s accuracy scores on the n-back task (i.e., 2-back condition) improved from 79% (baseline) to 96% (after DTMS treatment). dtms 121-125 solute carrier family 9 member A6 Homo sapiens 10-15 25977400-0 2015 Non-susceptibility to ceftaroline in healthcare-associated multiresistant MRSA in Eastern Australia. T 91825 22-33 solute carrier family 9 member A6 Homo sapiens 74-78 25246437-0 2015 The combination of ceftaroline plus daptomycin allows for therapeutic de-escalation and daptomycin sparing against MRSA. T 91825 19-30 solute carrier family 9 member A6 Homo sapiens 115-119 25966789-0 2015 Emodin is identified as the active component of ether extracts from Rhizoma Polygoni Cuspidati, for anti-MRSA activity. Ether 48-53 solute carrier family 9 member A6 Homo sapiens 105-109 25561733-5 2015 The Na(+)/H(+) exchanger NHE6 provides a leak pathway for protons, limiting luminal acidification by proton pumps. Phenobarbital 76-83 solute carrier family 9 member A6 Homo sapiens 25-29 25246437-0 2015 The combination of ceftaroline plus daptomycin allows for therapeutic de-escalation and daptomycin sparing against MRSA. Daptomycin 36-46 solute carrier family 9 member A6 Homo sapiens 115-119 25246437-1 2015 OBJECTIVES: We previously demonstrated that ceftaroline enhances daptomycin against MRSA in vitro. T 91825 44-55 solute carrier family 9 member A6 Homo sapiens 84-88 25246437-1 2015 OBJECTIVES: We previously demonstrated that ceftaroline enhances daptomycin against MRSA in vitro. Daptomycin 65-75 solute carrier family 9 member A6 Homo sapiens 84-88 25246437-10 2015 CONCLUSIONS: These findings confirm that ceftaroline+daptomycin is a potent combination against MRSA. T 91825 41-52 solute carrier family 9 member A6 Homo sapiens 96-100 25246437-10 2015 CONCLUSIONS: These findings confirm that ceftaroline+daptomycin is a potent combination against MRSA. Daptomycin 53-63 solute carrier family 9 member A6 Homo sapiens 96-100 24313336-6 2015 At the neural level, Mrs A showed significantly increased brain activity in the working memory network (e.g., DLPFC, parietal cortex) during the execution of the 2-back condition after DTMS treatment compared to baseline. dtms 185-189 solute carrier family 9 member A6 Homo sapiens 21-26 26168679-4 2015 The highest levels of the MRSA resistance were stated against ciprofloxacin--92%(MIC50 32 mcg/ml), gentamicin--85% (MIC50 128 mcg/ml), erythromycin--54% (MIC50 32-mcg/ml) and clindainycin - 45% (MIC50 0.03 mcg/ml), as well as against rifampicin--38% (MIC50 0.06 mcg/ml). Ciprofloxacin 62-75 solute carrier family 9 member A6 Homo sapiens 26-30 27141645-0 2015 [Results of Investigation of MRSA Susceptibility to Vancomycin in Clinical Units of Large Multifunctional Hospital and Recommendations on Optimization of Antibacterial Therapy of Staphylococcal Infection]. Vancomycin 52-62 solute carrier family 9 member A6 Homo sapiens 29-33 25672426-1 2015 OBJECTIVE: To establish the risk factors for joint infection by oxacillin-resistant Staphylococcus aureus (MRSA) using clinical and epidemiological data. Oxacillin 64-73 solute carrier family 9 member A6 Homo sapiens 107-111 25209610-0 2015 Randomized non-inferiority trial to compare trimethoprim/sulfamethoxazole plus rifampicin versus linezolid for the treatment of MRSA infection. Trimethoprim, Sulfamethoxazole Drug Combination 44-73 solute carrier family 9 member A6 Homo sapiens 128-132 25209610-0 2015 Randomized non-inferiority trial to compare trimethoprim/sulfamethoxazole plus rifampicin versus linezolid for the treatment of MRSA infection. Linezolid 97-106 solute carrier family 9 member A6 Homo sapiens 128-132 25209610-2 2015 The aim of this study was to assess the non-inferiority of a combination of trimethoprim/sulfamethoxazole plus rifampicin versus linezolid alone for the treatment of MRSA infection. Trimethoprim, Sulfamethoxazole Drug Combination 76-105 solute carrier family 9 member A6 Homo sapiens 166-170 25209610-2 2015 The aim of this study was to assess the non-inferiority of a combination of trimethoprim/sulfamethoxazole plus rifampicin versus linezolid alone for the treatment of MRSA infection. Rifampin 111-121 solute carrier family 9 member A6 Homo sapiens 166-170 25209610-13 2015 CONCLUSIONS: Compared with linezolid, trimethoprim/sulfamethoxazole and rifampicin seems to be non-inferior in the treatment of MRSA infection. Trimethoprim, Sulfamethoxazole Drug Combination 38-67 solute carrier family 9 member A6 Homo sapiens 128-132 25209610-13 2015 CONCLUSIONS: Compared with linezolid, trimethoprim/sulfamethoxazole and rifampicin seems to be non-inferior in the treatment of MRSA infection. Rifampin 72-82 solute carrier family 9 member A6 Homo sapiens 128-132 26168679-4 2015 The highest levels of the MRSA resistance were stated against ciprofloxacin--92%(MIC50 32 mcg/ml), gentamicin--85% (MIC50 128 mcg/ml), erythromycin--54% (MIC50 32-mcg/ml) and clindainycin - 45% (MIC50 0.03 mcg/ml), as well as against rifampicin--38% (MIC50 0.06 mcg/ml). Gentamicins 99-109 solute carrier family 9 member A6 Homo sapiens 26-30 27141645-4 2015 The use of the E-test for MRSA susceptibility to vancomycin allowed to estimate the validity of the use of various antibiotics active against MRSA in the treatment of inpatients and to reduce the risk of ineffective therapy. Vancomycin 49-59 solute carrier family 9 member A6 Homo sapiens 26-30 27141645-4 2015 The use of the E-test for MRSA susceptibility to vancomycin allowed to estimate the validity of the use of various antibiotics active against MRSA in the treatment of inpatients and to reduce the risk of ineffective therapy. Vancomycin 49-59 solute carrier family 9 member A6 Homo sapiens 142-146 26168679-4 2015 The highest levels of the MRSA resistance were stated against ciprofloxacin--92%(MIC50 32 mcg/ml), gentamicin--85% (MIC50 128 mcg/ml), erythromycin--54% (MIC50 32-mcg/ml) and clindainycin - 45% (MIC50 0.03 mcg/ml), as well as against rifampicin--38% (MIC50 0.06 mcg/ml). Erythromycin 135-147 solute carrier family 9 member A6 Homo sapiens 26-30 26168679-4 2015 The highest levels of the MRSA resistance were stated against ciprofloxacin--92%(MIC50 32 mcg/ml), gentamicin--85% (MIC50 128 mcg/ml), erythromycin--54% (MIC50 32-mcg/ml) and clindainycin - 45% (MIC50 0.03 mcg/ml), as well as against rifampicin--38% (MIC50 0.06 mcg/ml). clindainycin 175-187 solute carrier family 9 member A6 Homo sapiens 26-30 26168679-4 2015 The highest levels of the MRSA resistance were stated against ciprofloxacin--92%(MIC50 32 mcg/ml), gentamicin--85% (MIC50 128 mcg/ml), erythromycin--54% (MIC50 32-mcg/ml) and clindainycin - 45% (MIC50 0.03 mcg/ml), as well as against rifampicin--38% (MIC50 0.06 mcg/ml). Rifampin 234-244 solute carrier family 9 member A6 Homo sapiens 26-30 26168679-5 2015 The frequency of MRSA isolated at the vancomycin dose of 2 mcg/ml equaled 26%. Vancomycin 38-48 solute carrier family 9 member A6 Homo sapiens 17-21 26168679-7 2015 In 5% of MRSA isolated from infected surgical wounds in patients with bone infection or sepsis, there was observed a decrease in the susceptibility to ceftarolin (MIC 2-4 mcg/ml). ceftarolin 151-161 solute carrier family 9 member A6 Homo sapiens 9-13 24831298-1 2015 Mrs A, a 68-year-old woman with paranoid schizophrenia, was on long-term psychiatric treatment with long-acting intramuscular zuclopenthixol, quetiapine and alprazolam when, in April 2012, she was diagnosed with right breast infiltrating ductal carcinoma. Clopenthixol 126-140 solute carrier family 9 member A6 Homo sapiens 0-5 24831298-1 2015 Mrs A, a 68-year-old woman with paranoid schizophrenia, was on long-term psychiatric treatment with long-acting intramuscular zuclopenthixol, quetiapine and alprazolam when, in April 2012, she was diagnosed with right breast infiltrating ductal carcinoma. Quetiapine Fumarate 142-152 solute carrier family 9 member A6 Homo sapiens 0-5 24831298-1 2015 Mrs A, a 68-year-old woman with paranoid schizophrenia, was on long-term psychiatric treatment with long-acting intramuscular zuclopenthixol, quetiapine and alprazolam when, in April 2012, she was diagnosed with right breast infiltrating ductal carcinoma. Alprazolam 157-167 solute carrier family 9 member A6 Homo sapiens 0-5 24831298-2 2015 After starting treatment with letrozole on 4 July, Mrs A progressively developed extrapyramidal symptoms and these were particularly evident after each zuclopenthixol administration. Letrozole 30-39 solute carrier family 9 member A6 Homo sapiens 51-56 24831298-2 2015 After starting treatment with letrozole on 4 July, Mrs A progressively developed extrapyramidal symptoms and these were particularly evident after each zuclopenthixol administration. Clopenthixol 152-166 solute carrier family 9 member A6 Homo sapiens 51-56 25103488-2 2014 OBJECTIVES: After the implementation of an active surveillance programme for MRSA in US Veterans Affairs (VA) Medical Centers, there was an increase in vancomycin use. Vancomycin 152-162 solute carrier family 9 member A6 Homo sapiens 77-81 24934663-8 2015 A combination of rifampin and clarithromycin released from the polymer film provided >99.9% kill of an MRSA inoculate for up to 72 h. CONCLUSION: Results showed that combining multiple drugs in copolymer films with unique surface properties, initial hydrophilicity and increase in roughness, can be an effective way to prevent biofilm formation. Rifampin 17-25 solute carrier family 9 member A6 Homo sapiens 106-110 24934663-8 2015 A combination of rifampin and clarithromycin released from the polymer film provided >99.9% kill of an MRSA inoculate for up to 72 h. CONCLUSION: Results showed that combining multiple drugs in copolymer films with unique surface properties, initial hydrophilicity and increase in roughness, can be an effective way to prevent biofilm formation. Clarithromycin 30-44 solute carrier family 9 member A6 Homo sapiens 106-110 24934663-8 2015 A combination of rifampin and clarithromycin released from the polymer film provided >99.9% kill of an MRSA inoculate for up to 72 h. CONCLUSION: Results showed that combining multiple drugs in copolymer films with unique surface properties, initial hydrophilicity and increase in roughness, can be an effective way to prevent biofilm formation. copolymer 197-206 solute carrier family 9 member A6 Homo sapiens 106-110 25288400-7 2015 Forty-one percent of S. aureus strains isolated in all the patients were resistant to methicillin (MRSA). Methicillin 86-97 solute carrier family 9 member A6 Homo sapiens 99-103 25429539-0 2014 [Zinforo (ceftaroline fosamil)--A new beta-lactam-cephalosporin with MRSA activity]. Ceftaroline fosamil acetate 1-8 solute carrier family 9 member A6 Homo sapiens 70-74 25429539-0 2014 [Zinforo (ceftaroline fosamil)--A new beta-lactam-cephalosporin with MRSA activity]. ceftaroline fosamil 11-30 solute carrier family 9 member A6 Homo sapiens 70-74 25429539-0 2014 [Zinforo (ceftaroline fosamil)--A new beta-lactam-cephalosporin with MRSA activity]. beta-lactam-cephalosporin 39-64 solute carrier family 9 member A6 Homo sapiens 70-74 24090639-11 2014 These results suggest that deletion of (370)Trp-Ser-Thr(372) leads to endoplasmic reticulum retention and loss of NHE6 function which potentially impacts the trafficking of other membrane-bound cargo and cell polarity. Threonine 52-55 solute carrier family 9 member A6 Homo sapiens 114-118 25137207-4 2014 In addition to MRSA, the greatest danger in relation to antibiotic resistance worldwide are now considered tob e carbapenem-resistant Enterobacteriaceae (CRE) or multidrug-resistant Gram-negative (4MRGN) bacteria. Carbapenems 113-123 solute carrier family 9 member A6 Homo sapiens 15-19 24816900-10 2014 CA-MRSA decontamination using mupirocin and chlorhexidine in the community setting may also be a questionable strategy, associated with failure and resistance to both agents. Mupirocin 30-39 solute carrier family 9 member A6 Homo sapiens 3-7 24816900-10 2014 CA-MRSA decontamination using mupirocin and chlorhexidine in the community setting may also be a questionable strategy, associated with failure and resistance to both agents. Chlorhexidine 44-57 solute carrier family 9 member A6 Homo sapiens 3-7 24239015-0 2013 Structure-anti-MRSA activity relationship of macrocyclic bis(bibenzyl) derivatives. bis(bibenzyl) 57-70 solute carrier family 9 member A6 Homo sapiens 15-19 24885158-11 2014 Most MRSA patients (66%, 88/134) were treated empirically (primarily vancomycin) but outcome was not improved by receipt of empiric therapy. Vancomycin 69-79 solute carrier family 9 member A6 Homo sapiens 5-9 24239015-2 2013 The structure-activity relationships and the results of molecular dynamics simulations indicated that bis(bibenzyl)s with potent anti-MRSA activity commonly have a 4-hydroxyl group at the D-benzene ring and a 2-hydroxyl group at the C-benzene ring in the hydrophilic part of the molecule, and an unsubstituted phenoxyphenyl group in the hydrophobic part of the molecule containing the A-B-benzene rings. bis(bibenzyl)s 102-116 solute carrier family 9 member A6 Homo sapiens 134-138 24239015-2 2013 The structure-activity relationships and the results of molecular dynamics simulations indicated that bis(bibenzyl)s with potent anti-MRSA activity commonly have a 4-hydroxyl group at the D-benzene ring and a 2-hydroxyl group at the C-benzene ring in the hydrophilic part of the molecule, and an unsubstituted phenoxyphenyl group in the hydrophobic part of the molecule containing the A-B-benzene rings. Deuterium 188-189 solute carrier family 9 member A6 Homo sapiens 134-138 25000521-4 2014 To test this, we identified the proportion of MC398 in MRSA positive individuals without contact with pigs/veal calves or other known risk factors (MRSA of unknown origin; MUO). mc398 46-51 solute carrier family 9 member A6 Homo sapiens 55-59 24668837-0 2014 Teicoplanin for treating MRSA pneumonia. Teicoplanin 0-11 solute carrier family 9 member A6 Homo sapiens 25-29 24165181-1 2014 The purpose of this study was to compare the clinical efficacy and safety of vancomycin to those of teicoplanin for the treatment of adult patients with health care-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) bacteremia. Vancomycin 77-87 solute carrier family 9 member A6 Homo sapiens 224-228 24165181-10 2014 This study indicates that teicoplanin is an effective and safe alternative to vancomycin for the treatment of HA-MRSA bacteremia. Teicoplanin 26-37 solute carrier family 9 member A6 Homo sapiens 113-117 23499479-7 2013 The incidence of fluoroquinolone resistance in HA-MRSA is remarkably high, suggesting use of this class of antibiotics as well as the beta-lactams contributes to the selection and success of HA-MRSA clones in the hospital setting. Fluoroquinolones 17-32 solute carrier family 9 member A6 Homo sapiens 50-54 24063393-0 2013 GenomEra MRSA/SA, a fully automated homogeneous PCR assay for rapid detection of Staphylococcus aureus and the marker of methicillin resistance in various sample matrixes. Methicillin 121-132 solute carrier family 9 member A6 Homo sapiens 9-13 24063393-3 2013 It can be used for both screening and confirmation of methicillin-resistant and -sensitive S. aureus (MRSA and MSSA) directly in different specimen types or from preceding cultures. Methicillin 54-65 solute carrier family 9 member A6 Homo sapiens 102-106 24239015-2 2013 The structure-activity relationships and the results of molecular dynamics simulations indicated that bis(bibenzyl)s with potent anti-MRSA activity commonly have a 4-hydroxyl group at the D-benzene ring and a 2-hydroxyl group at the C-benzene ring in the hydrophilic part of the molecule, and an unsubstituted phenoxyphenyl group in the hydrophobic part of the molecule containing the A-B-benzene rings. Benzene 190-197 solute carrier family 9 member A6 Homo sapiens 134-138 24239015-2 2013 The structure-activity relationships and the results of molecular dynamics simulations indicated that bis(bibenzyl)s with potent anti-MRSA activity commonly have a 4-hydroxyl group at the D-benzene ring and a 2-hydroxyl group at the C-benzene ring in the hydrophilic part of the molecule, and an unsubstituted phenoxyphenyl group in the hydrophobic part of the molecule containing the A-B-benzene rings. Benzene 235-242 solute carrier family 9 member A6 Homo sapiens 134-138 24239015-2 2013 The structure-activity relationships and the results of molecular dynamics simulations indicated that bis(bibenzyl)s with potent anti-MRSA activity commonly have a 4-hydroxyl group at the D-benzene ring and a 2-hydroxyl group at the C-benzene ring in the hydrophilic part of the molecule, and an unsubstituted phenoxyphenyl group in the hydrophobic part of the molecule containing the A-B-benzene rings. Benzene 235-242 solute carrier family 9 member A6 Homo sapiens 134-138 24239015-3 2013 Pharmacological characterization of the bis(bibenzyl) derivatives and 2-phenoxyphenol fragment 25, previously proposed as the minimum structure of riccardin C 1 for anti-MRSA activity, indicated that they have different action mechanisms: the bis(bibenzyl)s are bactericidal, while 25 is bacteriostatic, showing only weak bactericidal activity. Carbon 157-158 solute carrier family 9 member A6 Homo sapiens 170-174 24260299-0 2013 Teicoplanin as an effective alternative to vancomycin for treatment of MRSA infection in Chinese population: a meta-analysis of randomized controlled trials. Teicoplanin 0-11 solute carrier family 9 member A6 Homo sapiens 71-75 24260299-7 2013 CONCLUSIONS: The meta-analysis results indicate that the two therapies are similar in both efficacy and safety, thus teicoplanin can act as an effective alternative to vancomycin for treating patients infected by MRSA. Teicoplanin 117-128 solute carrier family 9 member A6 Homo sapiens 213-217 24068869-2 2013 Our objective was to develop an economic model from a US payer perspective that includes all direct inpatient and outpatient costs incurred by patients with MRSA cSSTI receiving linezolid, vancomycin, or daptomycin. Linezolid 178-187 solute carrier family 9 member A6 Homo sapiens 157-167 24068869-2 2013 Our objective was to develop an economic model from a US payer perspective that includes all direct inpatient and outpatient costs incurred by patients with MRSA cSSTI receiving linezolid, vancomycin, or daptomycin. Vancomycin 189-199 solute carrier family 9 member A6 Homo sapiens 157-167 24068869-2 2013 Our objective was to develop an economic model from a US payer perspective that includes all direct inpatient and outpatient costs incurred by patients with MRSA cSSTI receiving linezolid, vancomycin, or daptomycin. Daptomycin 204-214 solute carrier family 9 member A6 Homo sapiens 157-167 24068869-13 2013 CONCLUSION: Outpatient costs of managing MRSA cSSTI may be reduced by 30%-50% with oral linezolid compared with vancomycin or daptomycin. Linezolid 88-97 solute carrier family 9 member A6 Homo sapiens 41-51 24068869-13 2013 CONCLUSION: Outpatient costs of managing MRSA cSSTI may be reduced by 30%-50% with oral linezolid compared with vancomycin or daptomycin. Vancomycin 112-122 solute carrier family 9 member A6 Homo sapiens 41-51 24068869-13 2013 CONCLUSION: Outpatient costs of managing MRSA cSSTI may be reduced by 30%-50% with oral linezolid compared with vancomycin or daptomycin. Daptomycin 126-136 solute carrier family 9 member A6 Homo sapiens 41-51 23499479-7 2013 The incidence of fluoroquinolone resistance in HA-MRSA is remarkably high, suggesting use of this class of antibiotics as well as the beta-lactams contributes to the selection and success of HA-MRSA clones in the hospital setting. Fluoroquinolones 17-32 solute carrier family 9 member A6 Homo sapiens 194-198 23499479-7 2013 The incidence of fluoroquinolone resistance in HA-MRSA is remarkably high, suggesting use of this class of antibiotics as well as the beta-lactams contributes to the selection and success of HA-MRSA clones in the hospital setting. beta-Lactams 134-146 solute carrier family 9 member A6 Homo sapiens 50-54 23499479-7 2013 The incidence of fluoroquinolone resistance in HA-MRSA is remarkably high, suggesting use of this class of antibiotics as well as the beta-lactams contributes to the selection and success of HA-MRSA clones in the hospital setting. beta-Lactams 134-146 solute carrier family 9 member A6 Homo sapiens 194-198 23150480-0 2012 MRSA in waste treatment water poses potential risk. Water 24-29 solute carrier family 9 member A6 Homo sapiens 0-4 23036849-0 2013 Accurate classification of childhood brain tumours by in vivo 1H MRS - a multi-centre study. Hydrogen 62-64 solute carrier family 9 member A6 Homo sapiens 65-72 24738238-0 2013 [Estimation of MRSA susceptibility to oxacillin, cefoxitine, vancomycin and daptomycin]. Oxacillin 38-47 solute carrier family 9 member A6 Homo sapiens 15-19 24738238-0 2013 [Estimation of MRSA susceptibility to oxacillin, cefoxitine, vancomycin and daptomycin]. Cefoxitin 49-59 solute carrier family 9 member A6 Homo sapiens 15-19 24738238-0 2013 [Estimation of MRSA susceptibility to oxacillin, cefoxitine, vancomycin and daptomycin]. Vancomycin 61-71 solute carrier family 9 member A6 Homo sapiens 15-19 24738238-0 2013 [Estimation of MRSA susceptibility to oxacillin, cefoxitine, vancomycin and daptomycin]. Daptomycin 76-86 solute carrier family 9 member A6 Homo sapiens 15-19 24738238-2 2013 Therefore, correct laboratory identification of the MRSA phenotype based on the use of the marker antibiotic cefoxitine, as a more susceptibile one vs. oxacillin, is of great importance. Cefoxitin 109-119 solute carrier family 9 member A6 Homo sapiens 52-56 24738238-2 2013 Therefore, correct laboratory identification of the MRSA phenotype based on the use of the marker antibiotic cefoxitine, as a more susceptibile one vs. oxacillin, is of great importance. Oxacillin 152-161 solute carrier family 9 member A6 Homo sapiens 52-56 24738238-3 2013 There is lately being observed a tendency towards emergence of strains with lower susceptibility to the last reserve drugs protecting from MRSA, i. e. vancomycin and daptomycin. Vancomycin 151-161 solute carrier family 9 member A6 Homo sapiens 139-143 24738238-3 2013 There is lately being observed a tendency towards emergence of strains with lower susceptibility to the last reserve drugs protecting from MRSA, i. e. vancomycin and daptomycin. Daptomycin 166-176 solute carrier family 9 member A6 Homo sapiens 139-143 24738238-5 2013 The results of our study on estimation of susceptibility of 316 MRSA isolates from several regions of Russia to oxacillin, cefoxitine, vancomycin and daptomycin are presented herein. Oxacillin 112-121 solute carrier family 9 member A6 Homo sapiens 64-68 24738238-5 2013 The results of our study on estimation of susceptibility of 316 MRSA isolates from several regions of Russia to oxacillin, cefoxitine, vancomycin and daptomycin are presented herein. Cefoxitin 123-133 solute carrier family 9 member A6 Homo sapiens 64-68 24738238-5 2013 The results of our study on estimation of susceptibility of 316 MRSA isolates from several regions of Russia to oxacillin, cefoxitine, vancomycin and daptomycin are presented herein. Vancomycin 135-145 solute carrier family 9 member A6 Homo sapiens 64-68 24738238-5 2013 The results of our study on estimation of susceptibility of 316 MRSA isolates from several regions of Russia to oxacillin, cefoxitine, vancomycin and daptomycin are presented herein. Daptomycin 150-160 solute carrier family 9 member A6 Homo sapiens 64-68 24738238-7 2013 As for cefoxitine, the MRSA isolates were rather resistant to it at the MIC > 16 mcg/ml. Cefoxitin 7-17 solute carrier family 9 member A6 Homo sapiens 23-27 24738238-10 2013 The MRSA isolates were highly susceptible to daptomycin, while high levels of the MIC (2 mcg/ml) were characteristic of 2.8 +/- 1% of the isolates. Daptomycin 45-55 solute carrier family 9 member A6 Homo sapiens 4-8 23936095-4 2013 The frequency of spontaneous mutants arising following exposure to fosfomycin, tobramycin and F:T was determined for clinical Pseudomonas aeruginosa and MRSA isolates under aerobic and anaerobic conditions. Fosfomycin 67-77 solute carrier family 9 member A6 Homo sapiens 153-157 23936095-6 2013 P. aeruginosa and MRSA isolates had a lower frequency of spontaneous mutants to F:T compared to fosfomycin and tobramycin under both aerobic and anaerobic conditions. Fosfomycin 96-106 solute carrier family 9 member A6 Homo sapiens 18-22 23936095-6 2013 P. aeruginosa and MRSA isolates had a lower frequency of spontaneous mutants to F:T compared to fosfomycin and tobramycin under both aerobic and anaerobic conditions. Tobramycin 111-121 solute carrier family 9 member A6 Homo sapiens 18-22 22371294-1 2012 PURPOSE: To evaluate the usefulness of daptomycin, tigecycline, and linezolid for the treatment of MRSA infection compared with vancomycin in Belgium, the United Kingdom/Ireland, and Spain. Linezolid 68-77 solute carrier family 9 member A6 Homo sapiens 99-103 22585351-3 2012 QUESTIONS/PURPOSES: We asked whether (1) C2DA inhibited MRSA growth and biofilm, (2) antibiotics increased inhibitory effects, (3) inhibitory concentrations of C2DA were cytotoxic to human cells, and (4) effective concentrations could be delivered from a chitosan sponge drug delivery device. 2-decenoic acid 41-45 solute carrier family 9 member A6 Homo sapiens 56-60 23109011-8 2012 In addition, among all tested antibiotics, vancomycin and nitrofurantion seem to be the most effective antibiotics for MR- SA. Vancomycin 43-53 solute carrier family 9 member A6 Homo sapiens 119-125 23109011-8 2012 In addition, among all tested antibiotics, vancomycin and nitrofurantion seem to be the most effective antibiotics for MR- SA. nitrofurantion 58-72 solute carrier family 9 member A6 Homo sapiens 119-125 22784260-8 2012 RESULTS: Of the 7,183 patients with cSSSI, 2,387 (33.2%) had MRSA. csssi 36-41 solute carrier family 9 member A6 Homo sapiens 61-65 22399220-1 2012 OBJECTIVE: To determine epidemiology and clinical characteristics of infants with methicillin-susceptible (MSSA) and -resistant Staphylococcus aureus (MRSA) in a level III neonatal intensive care unit (NICU). Methicillin 82-93 solute carrier family 9 member A6 Homo sapiens 151-155 22196908-6 2011 There is an increasing realisation that reducing the use of fluoroquinolones and third-generation cephalosporins (which have been associated with increased carriage of MRSA) in patient populations where MRSA is prevalent can be a useful control measure. Fluoroquinolones 60-76 solute carrier family 9 member A6 Homo sapiens 168-172 22397861-1 2012 Preoperative screening and decolonization of methicillin-sensitive and methicillin-resistant Staphylococcus aureus (MSSA and MRSA, respectively) are advocated to reduce surgical site infections. Methicillin 45-56 solute carrier family 9 member A6 Homo sapiens 125-129 22500244-2 2012 Although vancomycin has been considered a gold standard for the therapy of MRSA pneumonia, clinical failure rates have also been reported owing to its slow, time-dependent bactericidal activity, variable lung tissue penetration and poor intracellular penetration into macrophages. Vancomycin 9-19 solute carrier family 9 member A6 Homo sapiens 75-79 22397861-1 2012 Preoperative screening and decolonization of methicillin-sensitive and methicillin-resistant Staphylococcus aureus (MSSA and MRSA, respectively) are advocated to reduce surgical site infections. Methicillin 71-82 solute carrier family 9 member A6 Homo sapiens 125-129 22607475-9 2012 Transmission rates were higher in pigs treated with tetracyclins and beta-lactams compared to untreated pigs implying a selective advantage of MRSA CC398 when these antimicrobials are used. tetracyclins 52-64 solute carrier family 9 member A6 Homo sapiens 143-147 22607475-9 2012 Transmission rates were higher in pigs treated with tetracyclins and beta-lactams compared to untreated pigs implying a selective advantage of MRSA CC398 when these antimicrobials are used. beta-Lactams 69-81 solute carrier family 9 member A6 Homo sapiens 143-147 22301774-4 2012 Additionally some 2-aminopyrmidines were able to suppress MRSA resistance to conventional antibiotics. 2-aminopyrmidines 18-35 solute carrier family 9 member A6 Homo sapiens 58-62 22196908-6 2011 There is an increasing realisation that reducing the use of fluoroquinolones and third-generation cephalosporins (which have been associated with increased carriage of MRSA) in patient populations where MRSA is prevalent can be a useful control measure. Fluoroquinolones 60-76 solute carrier family 9 member A6 Homo sapiens 203-207 22196908-6 2011 There is an increasing realisation that reducing the use of fluoroquinolones and third-generation cephalosporins (which have been associated with increased carriage of MRSA) in patient populations where MRSA is prevalent can be a useful control measure. Cephalosporins 98-112 solute carrier family 9 member A6 Homo sapiens 168-172 22196908-6 2011 There is an increasing realisation that reducing the use of fluoroquinolones and third-generation cephalosporins (which have been associated with increased carriage of MRSA) in patient populations where MRSA is prevalent can be a useful control measure. Cephalosporins 98-112 solute carrier family 9 member A6 Homo sapiens 203-207 21327600-5 2011 In all of the patients with MRSA-positive bile culture, vancomycin was prophylactically administered after surgery. Vancomycin 56-66 solute carrier family 9 member A6 Homo sapiens 28-32 21682676-3 2011 The main regime of antibiotic treatment recommended for MRSA pneumonia is either vancomycin or linezolid. Vancomycin 81-91 solute carrier family 9 member A6 Homo sapiens 56-60 21682676-3 2011 The main regime of antibiotic treatment recommended for MRSA pneumonia is either vancomycin or linezolid. Linezolid 95-104 solute carrier family 9 member A6 Homo sapiens 56-60 21511410-0 2011 Decreased susceptibility of MRSA ST398 to tiamulin. tiamulin 42-50 solute carrier family 9 member A6 Homo sapiens 28-32 21685529-10 2011 In cases of empirical administration, it is necessary to use antibiotics with high level of activity against pneumonia agents - carbapenems, and in case of high probability of MRSA - it is better to use linezolid or vancomicin. Linezolid 203-212 solute carrier family 9 member A6 Homo sapiens 176-180 21685529-10 2011 In cases of empirical administration, it is necessary to use antibiotics with high level of activity against pneumonia agents - carbapenems, and in case of high probability of MRSA - it is better to use linezolid or vancomicin. Vancomycin 216-226 solute carrier family 9 member A6 Homo sapiens 176-180 20714913-0 2011 An initial dosing method for teicoplanin based on the area under the serum concentration time curve required for MRSA eradication. Teicoplanin 29-40 solute carrier family 9 member A6 Homo sapiens 113-117 21977823-9 2011 16% of MRSA carriers develop an infection that needs to be treated with vancomycin. Vancomycin 72-82 solute carrier family 9 member A6 Homo sapiens 7-11 21839399-2 2011 OBJECTIVE: A decision analytic (DA) model was developed to evaluate the cost-effectiveness analysis (CEA) of linezolid, daptomycin, and vancomycin in MRSA cSSSI. Linezolid 109-118 solute carrier family 9 member A6 Homo sapiens 150-160 21839399-2 2011 OBJECTIVE: A decision analytic (DA) model was developed to evaluate the cost-effectiveness analysis (CEA) of linezolid, daptomycin, and vancomycin in MRSA cSSSI. Vancomycin 136-146 solute carrier family 9 member A6 Homo sapiens 150-160 21839399-6 2011 Primary outcome was the incremental cost-effectiveness ratio between linezolid and vancomycin, daptomycin and vancomycin, and linezolid and daptomycin in MRSA cSSSI. Daptomycin 140-150 solute carrier family 9 member A6 Homo sapiens 154-164 21839399-13 2011 CONCLUSION: Linezolid and daptomycin are potentially cost-effective based on the assumptions of the DA model; however, linezolid appears to be more cost-effective compared to daptomycin and vancomycin for MRSA cSSSIs. Linezolid 119-128 solute carrier family 9 member A6 Homo sapiens 205-209 21839399-13 2011 CONCLUSION: Linezolid and daptomycin are potentially cost-effective based on the assumptions of the DA model; however, linezolid appears to be more cost-effective compared to daptomycin and vancomycin for MRSA cSSSIs. Vancomycin 190-200 solute carrier family 9 member A6 Homo sapiens 205-209 21455712-0 2011 Glycopeptide and daptomycin resistance in community-associated MRSA in the UK. Glycopeptides 0-12 solute carrier family 9 member A6 Homo sapiens 63-67 21455712-0 2011 Glycopeptide and daptomycin resistance in community-associated MRSA in the UK. Daptomycin 17-27 solute carrier family 9 member A6 Homo sapiens 63-67 22204200-1 2011 OBJECTIVE: To evaluate the trend of mupirocin resistance in MRSA, isolated at the Clinical Microbiology Laboratory of a tertiary care hospital. Mupirocin 36-45 solute carrier family 9 member A6 Homo sapiens 60-64 22204200-3 2011 RESULTS: High level and low level mupirocin resistance were detected in zero and 1% of MRSA strains, respectively. Mupirocin 34-43 solute carrier family 9 member A6 Homo sapiens 87-91 22204200-6 2011 CONCLUSION: Mupirocin resistance was found to be very low among local clinical isolates of MRSA. Mupirocin 12-21 solute carrier family 9 member A6 Homo sapiens 91-95 21229280-0 2011 Vancomycin MIC creep in MRSA blood culture isolates from Germany: a regional problem? Vancomycin 0-10 solute carrier family 9 member A6 Homo sapiens 24-28 21229280-1 2011 The aim of this study was to assess the vancomycin MIC distribution for MRSA blood culture isolates over a period of six years in Germany. Vancomycin 40-50 solute carrier family 9 member A6 Homo sapiens 72-76 21229280-4 2011 Genotypic features of the MRSA strains with vancomycin MIC >= 1 mg/L were determined by semiautomated repetitive-sequence-based polymerase chain reaction. Vancomycin 44-54 solute carrier family 9 member A6 Homo sapiens 26-30 21229280-10 2011 We suggest that all hospitals should monitor their local status of elevated vancomycin MICs in invasive MRSA isolates. Vancomycin 76-86 solute carrier family 9 member A6 Homo sapiens 104-108 21211014-1 2011 BACKGROUND: Staphylococcus aureus including methicillin resistant S. aureus, MRSA, are human colonizing bacteria that commonly cause opportunistic infections primarily involving the skin in otherwise healthy individuals. Methicillin 44-55 solute carrier family 9 member A6 Homo sapiens 77-81 21132518-0 2011 Bio-inspired porous SiC ceramics loaded with vancomycin for preventing MRSA infections. Vancomycin 45-55 solute carrier family 9 member A6 Homo sapiens 71-75 21211014-7 2011 Twelve of 15 MRSA isolates collected from the water had identical genetic characteristics as the organisms isolated from the participants exposed to that water while the remaining 3 MRSA were without matching nasal isolates from participants. Water 46-51 solute carrier family 9 member A6 Homo sapiens 13-17 21211014-7 2011 Twelve of 15 MRSA isolates collected from the water had identical genetic characteristics as the organisms isolated from the participants exposed to that water while the remaining 3 MRSA were without matching nasal isolates from participants. Water 154-159 solute carrier family 9 member A6 Homo sapiens 13-17 21144988-3 2011 Their use in the intensive care unit as empiric therapy is becoming compromised due to the development of multiple drug resistant gram negative pathogens and collateral damage with C difficile & MRSA. difficile 183-192 solute carrier family 9 member A6 Homo sapiens 199-203 21144988-3 2011 Their use in the intensive care unit as empiric therapy is becoming compromised due to the development of multiple drug resistant gram negative pathogens and collateral damage with C difficile & MRSA. Adenosine Monophosphate 194-197 solute carrier family 9 member A6 Homo sapiens 199-203 22830148-12 2011 Linezolid was used for MRSA. Linezolid 0-9 solute carrier family 9 member A6 Homo sapiens 23-27 22830148-19 2011 MRSA was treated successfully with Linezolid. Linezolid 35-44 solute carrier family 9 member A6 Homo sapiens 0-4 20483504-0 2010 Oxacillin-susceptible MRSA, the emerging MRSA clone in the UK? Oxacillin 0-9 solute carrier family 9 member A6 Homo sapiens 22-26 20949524-2 2010 Gilfillan et al.2008] reported mutations in SLC9A6, the gene encoding the sodium/hydrogen exchanger NHE6, in the family first reported and in three others. Sodium 74-80 solute carrier family 9 member A6 Homo sapiens 44-50 20949524-2 2010 Gilfillan et al.2008] reported mutations in SLC9A6, the gene encoding the sodium/hydrogen exchanger NHE6, in the family first reported and in three others. Sodium 74-80 solute carrier family 9 member A6 Homo sapiens 100-104 20949524-2 2010 Gilfillan et al.2008] reported mutations in SLC9A6, the gene encoding the sodium/hydrogen exchanger NHE6, in the family first reported and in three others. Hydrogen 81-89 solute carrier family 9 member A6 Homo sapiens 44-50 20949524-2 2010 Gilfillan et al.2008] reported mutations in SLC9A6, the gene encoding the sodium/hydrogen exchanger NHE6, in the family first reported and in three others. Hydrogen 81-89 solute carrier family 9 member A6 Homo sapiens 100-104 20483504-0 2010 Oxacillin-susceptible MRSA, the emerging MRSA clone in the UK? Oxacillin 0-9 solute carrier family 9 member A6 Homo sapiens 41-45 20429820-11 2010 The finding of lower vancomycin efficacy in MRSA cSSTI did not change in sensitivity analyses. Vancomycin 21-31 solute carrier family 9 member A6 Homo sapiens 44-48 20429820-12 2010 CONCLUSION: The results of this meta-analysis suggest higher success rates for linezolid and the new glycopeptides (dalbavancin and telavancin) in MRSA-confirmed cSSTIs. Linezolid 79-88 solute carrier family 9 member A6 Homo sapiens 147-151 20429820-12 2010 CONCLUSION: The results of this meta-analysis suggest higher success rates for linezolid and the new glycopeptides (dalbavancin and telavancin) in MRSA-confirmed cSSTIs. Glycopeptides 101-114 solute carrier family 9 member A6 Homo sapiens 147-151 20429820-12 2010 CONCLUSION: The results of this meta-analysis suggest higher success rates for linezolid and the new glycopeptides (dalbavancin and telavancin) in MRSA-confirmed cSSTIs. dalbavancin 116-127 solute carrier family 9 member A6 Homo sapiens 147-151 20429820-12 2010 CONCLUSION: The results of this meta-analysis suggest higher success rates for linezolid and the new glycopeptides (dalbavancin and telavancin) in MRSA-confirmed cSSTIs. telavancin 132-142 solute carrier family 9 member A6 Homo sapiens 147-151 22338440-17 2010 except MRSA where Linezolid, vancomycin and Tiecoplanin were effective. tiecoplanin 44-55 solute carrier family 9 member A6 Homo sapiens 7-11 20001574-0 2010 Efficacy and safety of linezolid in methicillin-resistant Staphylococcus aureus (MRSA) complicated skin and soft tissue infection (cSSTI): a meta-analysis. Linezolid 23-32 solute carrier family 9 member A6 Homo sapiens 81-85 20381913-0 2010 Mupirocin-resistant MRSA transmission associated with community hospitals and nursing homes. Mupirocin 0-9 solute carrier family 9 member A6 Homo sapiens 20-24 20364249-9 2010 However, NHE6 with alanine substitutions in the membrane-proximal region exhibited no apparent change in localization. Alanine 19-26 solute carrier family 9 member A6 Homo sapiens 9-13 20001574-1 2010 OBJECTIVE: To evaluate the clinical and microbiological outcomes of linezolid versus vancomycin in methicillin-resistant Staphylococcus aureus (MRSA) complicated skin and soft-tissue infection (cSSTI) using a meta-analysis. Vancomycin 85-95 solute carrier family 9 member A6 Homo sapiens 144-148 20001574-10 2010 Microbiological eradication in MRSA ME patients consistently favored the use of linezolid over vancomycin (OR = 2.90; 95% CI: 1.90, 4.41). Linezolid 80-89 solute carrier family 9 member A6 Homo sapiens 31-35 20001574-10 2010 Microbiological eradication in MRSA ME patients consistently favored the use of linezolid over vancomycin (OR = 2.90; 95% CI: 1.90, 4.41). Vancomycin 95-105 solute carrier family 9 member A6 Homo sapiens 31-35 20001574-15 2010 CONCLUSION: Resolution of infection in CE and MITT patients were inconsistent; however, a sub-analysis revealed that linezolid was more likely to consistently achieve microbiologic eradication in MRSA ME patients. Linezolid 117-126 solute carrier family 9 member A6 Homo sapiens 196-200 20001574-16 2010 Apparent risks of thrombocytopenia, nausea, diarrhea, and possibly anemia may limit linezolid use in treating MRSA cSSTI. Linezolid 84-93 solute carrier family 9 member A6 Homo sapiens 110-120 19364845-1 2009 Limited treatment options are available for implant-associated infections caused by methicillin (meticillin)-resistant Staphylococcus aureus (MRSA). Methicillin 84-95 solute carrier family 9 member A6 Homo sapiens 142-146 19846648-1 2009 The clinical utility of real-time PCR screening assays for methicillin (methicillin)-resistant Staphylococcus aureus (MRSA) colonization is constrained by the predictive values of their results: as MRSA prevalence falls, the assay"s positive predictive value (PPV) drops, and a rising proportion of positive PCR assays will not be confirmed by culture. Methicillin 59-70 solute carrier family 9 member A6 Homo sapiens 118-122 19846648-1 2009 The clinical utility of real-time PCR screening assays for methicillin (methicillin)-resistant Staphylococcus aureus (MRSA) colonization is constrained by the predictive values of their results: as MRSA prevalence falls, the assay"s positive predictive value (PPV) drops, and a rising proportion of positive PCR assays will not be confirmed by culture. Methicillin 59-70 solute carrier family 9 member A6 Homo sapiens 198-202 19846648-1 2009 The clinical utility of real-time PCR screening assays for methicillin (methicillin)-resistant Staphylococcus aureus (MRSA) colonization is constrained by the predictive values of their results: as MRSA prevalence falls, the assay"s positive predictive value (PPV) drops, and a rising proportion of positive PCR assays will not be confirmed by culture. Methicillin 72-83 solute carrier family 9 member A6 Homo sapiens 118-122 19846648-1 2009 The clinical utility of real-time PCR screening assays for methicillin (methicillin)-resistant Staphylococcus aureus (MRSA) colonization is constrained by the predictive values of their results: as MRSA prevalence falls, the assay"s positive predictive value (PPV) drops, and a rising proportion of positive PCR assays will not be confirmed by culture. Methicillin 72-83 solute carrier family 9 member A6 Homo sapiens 198-202 20090137-1 2009 BACKGROUND & OBJECTIVE: Community acquired methicillin resistant Staphylococcus aureus (CA-MRSA) is a major global problem. Adenosine Monophosphate 12-15 solute carrier family 9 member A6 Homo sapiens 95-99 19364845-1 2009 Limited treatment options are available for implant-associated infections caused by methicillin (meticillin)-resistant Staphylococcus aureus (MRSA). Methicillin 97-107 solute carrier family 9 member A6 Homo sapiens 142-146 19364845-3 2009 The daptomycin MIC and the minimum bactericidal concentration in logarithmic phase and stationary growth phase of MRSA were 0.625, 0.625, and 20 microg/ml, respectively. Daptomycin 4-14 solute carrier family 9 member A6 Homo sapiens 114-118 19364845-4 2009 In time-kill studies, daptomycin showed rapid and concentration-dependent killing of MRSA in stationary growth phase. Daptomycin 22-32 solute carrier family 9 member A6 Homo sapiens 85-89 19364845-6 2009 In treatment studies, daptomycin alone reduced the planktonic MRSA counts by 0.3 log(10) CFU/ml, whereas in combination with rifampin, a reduction in the counts of >6 log(10) CFU/ml was observed. Daptomycin 22-32 solute carrier family 9 member A6 Homo sapiens 62-66 19364845-9 2009 In addition, daptomycin at a high dose (30 mg/kg) completely prevented the emergence of rifampin resistance in planktonic and adherent MRSA cells. Daptomycin 13-23 solute carrier family 9 member A6 Homo sapiens 135-139 19364845-9 2009 In addition, daptomycin at a high dose (30 mg/kg) completely prevented the emergence of rifampin resistance in planktonic and adherent MRSA cells. Rifampin 88-96 solute carrier family 9 member A6 Homo sapiens 135-139 19364845-10 2009 Daptomycin at a high dose, corresponding to 6 mg/kg in humans, in combination with rifampin showed the highest activity against planktonic and adherent MRSA. Daptomycin 0-10 solute carrier family 9 member A6 Homo sapiens 152-156 19364845-10 2009 Daptomycin at a high dose, corresponding to 6 mg/kg in humans, in combination with rifampin showed the highest activity against planktonic and adherent MRSA. Rifampin 83-91 solute carrier family 9 member A6 Homo sapiens 152-156 19364845-11 2009 Daptomycin plus rifampin is a promising treatment option for implant-associated MRSA infections. Daptomycin 0-10 solute carrier family 9 member A6 Homo sapiens 80-84 19364845-11 2009 Daptomycin plus rifampin is a promising treatment option for implant-associated MRSA infections. Rifampin 16-24 solute carrier family 9 member A6 Homo sapiens 80-84 19489364-8 2009 Our CA-MRSA isolates were 98.6% sensitive to trimethoprim-sulfamethoxasole, 94.4% sensitive to tetracycline, 90.8% sensitive to clindamycin, and 59.9% sensitive to levofloxacin. trimethoprim-sulfamethoxasole 45-74 solute carrier family 9 member A6 Homo sapiens 7-11 19344266-4 2009 PATIENTS: A cohort of 182 consecutive patients who developed nosocomial BSI due to methicillin-susceptible and methicillin-resistant S. aureus (MSSA and MRSA, respectively) RESULTS: Patients with MRSA BSI had a significantly longer total length of hospital and intensive care unit (ICU) stay before the onset of BSI and a higher average daily cost. Methicillin 83-94 solute carrier family 9 member A6 Homo sapiens 196-200 19344266-4 2009 PATIENTS: A cohort of 182 consecutive patients who developed nosocomial BSI due to methicillin-susceptible and methicillin-resistant S. aureus (MSSA and MRSA, respectively) RESULTS: Patients with MRSA BSI had a significantly longer total length of hospital and intensive care unit (ICU) stay before the onset of BSI and a higher average daily cost. Methicillin 111-122 solute carrier family 9 member A6 Homo sapiens 196-200 19417720-0 2009 Drugs for MRSA with reduced susceptibility to vancomycin. Vancomycin 46-56 solute carrier family 9 member A6 Homo sapiens 10-14 19489364-8 2009 Our CA-MRSA isolates were 98.6% sensitive to trimethoprim-sulfamethoxasole, 94.4% sensitive to tetracycline, 90.8% sensitive to clindamycin, and 59.9% sensitive to levofloxacin. Tetracycline 95-107 solute carrier family 9 member A6 Homo sapiens 7-11 19489364-8 2009 Our CA-MRSA isolates were 98.6% sensitive to trimethoprim-sulfamethoxasole, 94.4% sensitive to tetracycline, 90.8% sensitive to clindamycin, and 59.9% sensitive to levofloxacin. Clindamycin 128-139 solute carrier family 9 member A6 Homo sapiens 7-11 19489364-8 2009 Our CA-MRSA isolates were 98.6% sensitive to trimethoprim-sulfamethoxasole, 94.4% sensitive to tetracycline, 90.8% sensitive to clindamycin, and 59.9% sensitive to levofloxacin. Levofloxacin 164-176 solute carrier family 9 member A6 Homo sapiens 7-11 19053903-2 2008 The CA-MRSA strains are more likely to carry the genes for the Panton-Valentine leukocidin toxin and have increased susceptibility to non-beta-lactam antibiotics. beta-Lactams 138-149 solute carrier family 9 member A6 Homo sapiens 7-11 21794562-1 2008 One of the soft-tissue infections with a large clinical relevance is necrotizing fascitis produced by Streptococcus pyogenes and skin infections produced by Staphylococcus aureus, particularly due to the evermore frequent methylcillin (MRSA) resistant varieties. methylcillin 222-234 solute carrier family 9 member A6 Homo sapiens 236-240 18544597-0 2008 Susceptibility of 170 isolates of the USA300 clone of MRSA to macrolides, clindamycin and the novel ketolide cethromycin. Macrolides 62-72 solute carrier family 9 member A6 Homo sapiens 54-58 18544597-0 2008 Susceptibility of 170 isolates of the USA300 clone of MRSA to macrolides, clindamycin and the novel ketolide cethromycin. Clindamycin 74-85 solute carrier family 9 member A6 Homo sapiens 54-58 18544597-0 2008 Susceptibility of 170 isolates of the USA300 clone of MRSA to macrolides, clindamycin and the novel ketolide cethromycin. Ketolides 100-108 solute carrier family 9 member A6 Homo sapiens 54-58 18544597-0 2008 Susceptibility of 170 isolates of the USA300 clone of MRSA to macrolides, clindamycin and the novel ketolide cethromycin. cethromycin 109-120 solute carrier family 9 member A6 Homo sapiens 54-58 18372271-0 2008 A case report of the use of nanocrystalline silver dressing in the management of acute surgical site wound infected with MRSA to prevent cutaneous necrosis following revision surgery. nanocrystalline 28-43 solute carrier family 9 member A6 Homo sapiens 121-125 18585915-6 2008 Here, we discuss the roles of PVL, the arginine catabolic mobile element and phenol-soluble modulins in the pathogenesis of prevalent CA-MRSA strains. Phenol 77-83 solute carrier family 9 member A6 Homo sapiens 137-141 18722220-8 2008 All of the CA-MRSA strains identified in our study were susceptible to trimethoprim/sulfamethoxazole (TMP/SMX). Trimethoprim, Sulfamethoxazole Drug Combination 71-100 solute carrier family 9 member A6 Homo sapiens 14-18 18722220-8 2008 All of the CA-MRSA strains identified in our study were susceptible to trimethoprim/sulfamethoxazole (TMP/SMX). Trimethoprim, Sulfamethoxazole Drug Combination 102-109 solute carrier family 9 member A6 Homo sapiens 14-18 17513023-2 2007 About 40% of the strains are resistant to methicillin (MRSA). Methicillin 42-53 solute carrier family 9 member A6 Homo sapiens 55-59 17852899-0 2008 Long-term use of daptomycin for MRSA osteomyelitis and joint infection. Daptomycin 17-27 solute carrier family 9 member A6 Homo sapiens 32-36 21694913-4 2008 We present a case of a hemodialysis patient who developed osteomyelitis of the entire right hemipelvis due to MRSA bacteremia after repeated attempts at TCC salvage. Triclocarban 153-156 solute carrier family 9 member A6 Homo sapiens 110-114 17513023-6 2007 At the same time, intermediate sensitive and resistant MRSA strains to glycopeptides appeared. Glycopeptides 71-84 solute carrier family 9 member A6 Homo sapiens 55-59 17439976-0 2007 Low-level exposure of MRSA to octenidine dihydrochloride does not select for resistance. octenidine 30-56 solute carrier family 9 member A6 Homo sapiens 22-26 17933423-10 2007 Ciprofloxacin-containing media should be used with caution for MRSA screening in settings where ciprofloxacin-susceptible strains (including community-associated MRSA) are increasing in prevalence. Ciprofloxacin 0-13 solute carrier family 9 member A6 Homo sapiens 63-67 17933423-10 2007 Ciprofloxacin-containing media should be used with caution for MRSA screening in settings where ciprofloxacin-susceptible strains (including community-associated MRSA) are increasing in prevalence. Ciprofloxacin 0-13 solute carrier family 9 member A6 Homo sapiens 162-166 17563032-0 2007 Is high minimal inhibitory concentration of vancomycin a predictor of poor response in MRSA infections? vancomycin a 44-56 solute carrier family 9 member A6 Homo sapiens 87-91 17646910-3 2007 We wanted to assess the effectiveness of MRSA eradication procedures--especially octenidine whole body washings and mupirocin nasal ointment--under conditions of everyday life. octenidine 81-91 solute carrier family 9 member A6 Homo sapiens 41-45 17588430-5 2007 The patient had MRSA sepsis develop resistant to conventional therapy, which was successfully treated with daptomycin. Daptomycin 107-117 solute carrier family 9 member A6 Homo sapiens 16-20 17020429-0 2006 Cephalosporins for uncomplicated skin and skin structure infections in emerging community-acquired MRSA. Cephalosporins 0-14 solute carrier family 9 member A6 Homo sapiens 99-103 17157008-4 2007 Some of them exhibited superior antibacterial activity against quinolone-susceptible MRSA in comparison with clinically used fluoroquinolones, such as levofloxacin, ciprofloxacin, and gatifloxacin. Quinolones 63-72 solute carrier family 9 member A6 Homo sapiens 85-89 16716610-6 2006 A simple decision analysis model suggests that gentamicin should be used when the prevalence of MRSA reaches 10% and vancomycin when the prevalence reaches 50%. Gentamicins 47-57 solute carrier family 9 member A6 Homo sapiens 96-100 17198732-11 2007 However, 11/14 (79%) MRSA patients who received rifampin combinations, other than vancomycin and rifampin simultaneously, were apparently cured. Rifampin 48-56 solute carrier family 9 member A6 Homo sapiens 21-25 17020429-4 2006 In addition, the use of antimicrobial agents in infective strains that may be resistant does not appear to be associated with adverse patient-reported outcomes, suggesting that cephalosporins may still be effective in treating community-acquired MRSA-associated SSSIs. Cephalosporins 177-191 solute carrier family 9 member A6 Homo sapiens 246-250 16983899-4 2006 The presence of an atypical skin infection in patients with AD, particularly those unresponsive to conventional penicillinase-resistant penicillins and cephalosporins, should alert the clinician to the possibility of MRSA as the underlying etiology, and intervention should be directed accordingly. Cephalosporins 152-166 solute carrier family 9 member A6 Homo sapiens 217-221 17185859-0 2006 Beta-lactam antibiotic susceptibility testing of MRSA? beta-Lactams 0-11 solute carrier family 9 member A6 Homo sapiens 49-53 16903411-0 2006 Topical manuka honey for MRSA-contaminated skin ulcers. manuka honey 8-20 solute carrier family 9 member A6 Homo sapiens 25-29 16178292-1 2005 Patients were being transferred from nursing homes to hospital with MRSA in their PEG sites. Polyethylene Glycols 82-85 solute carrier family 9 member A6 Homo sapiens 68-72 16570547-3 2006 The choice of vancomycin over a cephalosporin may be justified in patients who are known carriers of MRSA. Vancomycin 14-24 solute carrier family 9 member A6 Homo sapiens 101-105 16570547-3 2006 The choice of vancomycin over a cephalosporin may be justified in patients who are known carriers of MRSA. Cephalosporins 32-45 solute carrier family 9 member A6 Homo sapiens 101-105 17340994-0 2006 [MIC and MBC of quinupristin/dalfopristin of erythromycin-resistant MRSA strains isolated from clinical specimens]. quinupristin 16-28 solute carrier family 9 member A6 Homo sapiens 68-72 17340994-0 2006 [MIC and MBC of quinupristin/dalfopristin of erythromycin-resistant MRSA strains isolated from clinical specimens]. dalfopristin 29-41 solute carrier family 9 member A6 Homo sapiens 68-72 17340994-0 2006 [MIC and MBC of quinupristin/dalfopristin of erythromycin-resistant MRSA strains isolated from clinical specimens]. Erythromycin 45-57 solute carrier family 9 member A6 Homo sapiens 68-72 17340994-1 2006 The MICs and MBCs of quinupristin/dalfopristin were determined for 22 clinical strains MRSA with inducible type of resistance to MLS-B and for 15 of their derivatives with constitutive resistance to MLS-B. quinupristin 21-33 solute carrier family 9 member A6 Homo sapiens 87-91 17340994-2 2006 For MRSA strains with inducible resistance to MLS-B the obtained results for quinupristin/ dalfopristin were: MIC50 = 0.25, MIC90 = 0.5, MBC50 = 1.0 and MBC90 = 1.0. quinupristin 77-89 solute carrier family 9 member A6 Homo sapiens 4-8 17340994-2 2006 For MRSA strains with inducible resistance to MLS-B the obtained results for quinupristin/ dalfopristin were: MIC50 = 0.25, MIC90 = 0.5, MBC50 = 1.0 and MBC90 = 1.0. dalfopristin 91-103 solute carrier family 9 member A6 Homo sapiens 4-8 17571573-7 2006 Teicoplanin was active against against all MRSA excepted one of the strain, with an reduced susceptibility. Teicoplanin 0-11 solute carrier family 9 member A6 Homo sapiens 43-47 16547394-6 2006 In conclusion, the Maeda"s nomogram regimen with a 1,000 mg vancomycin dose was shown to achieve target plasma levels of vancomycin at a higher rate and provide higher clinical efficacy in vancomycin therapy of MRSA pneumonia patients, as compared with the currently available standard dosage regimen. Vancomycin 60-70 solute carrier family 9 member A6 Homo sapiens 211-215 16547394-6 2006 In conclusion, the Maeda"s nomogram regimen with a 1,000 mg vancomycin dose was shown to achieve target plasma levels of vancomycin at a higher rate and provide higher clinical efficacy in vancomycin therapy of MRSA pneumonia patients, as compared with the currently available standard dosage regimen. Vancomycin 121-131 solute carrier family 9 member A6 Homo sapiens 211-215 16547394-6 2006 In conclusion, the Maeda"s nomogram regimen with a 1,000 mg vancomycin dose was shown to achieve target plasma levels of vancomycin at a higher rate and provide higher clinical efficacy in vancomycin therapy of MRSA pneumonia patients, as compared with the currently available standard dosage regimen. Vancomycin 121-131 solute carrier family 9 member A6 Homo sapiens 211-215 16424973-9 2006 These results suggest teicoplanin may be useful in patients undergoing orthopedic surgery when the prevalence of MRSA is high. Teicoplanin 22-33 solute carrier family 9 member A6 Homo sapiens 113-117 17009779-0 2006 [Small change, large effect--a new vancomycin derivative against MRSA]. Vancomycin 35-45 solute carrier family 9 member A6 Homo sapiens 65-70 16341337-1 2005 Staphylococcus aureus is a major cause of infections in both hospitals and communities, and is exhibiting increasing resistance to methicillin (methicillin-resistant S. aureus, MRSA) and related beta-lactams. Methicillin 131-142 solute carrier family 9 member A6 Homo sapiens 177-181 16341337-5 2005 Compared with those reported from the US and other countries, CA-MRSA isolates in Taiwan did not always harbor type IV staphylococcal cassette chromosome (SCCmec) and were resistant to multiple non-beta-lactam antibiotics, including clindamycin and macrolides. beta-Lactams 198-209 solute carrier family 9 member A6 Homo sapiens 65-69 16341337-5 2005 Compared with those reported from the US and other countries, CA-MRSA isolates in Taiwan did not always harbor type IV staphylococcal cassette chromosome (SCCmec) and were resistant to multiple non-beta-lactam antibiotics, including clindamycin and macrolides. Clindamycin 233-244 solute carrier family 9 member A6 Homo sapiens 65-69 16341337-5 2005 Compared with those reported from the US and other countries, CA-MRSA isolates in Taiwan did not always harbor type IV staphylococcal cassette chromosome (SCCmec) and were resistant to multiple non-beta-lactam antibiotics, including clindamycin and macrolides. Macrolides 249-259 solute carrier family 9 member A6 Homo sapiens 65-69 16262432-1 2005 The thiopeptide (or thiostrepton) antibiotics are a class of sulfur containing highly modified cyclic peptides with interesting biological properties, including reported activity against MRSA and malaria. Thiostrepton 20-32 solute carrier family 9 member A6 Homo sapiens 187-191 16262432-1 2005 The thiopeptide (or thiostrepton) antibiotics are a class of sulfur containing highly modified cyclic peptides with interesting biological properties, including reported activity against MRSA and malaria. Sulfur 61-67 solute carrier family 9 member A6 Homo sapiens 187-191 16262432-1 2005 The thiopeptide (or thiostrepton) antibiotics are a class of sulfur containing highly modified cyclic peptides with interesting biological properties, including reported activity against MRSA and malaria. Peptides, Cyclic 95-110 solute carrier family 9 member A6 Homo sapiens 187-191 16155048-1 2005 OBJECTIVE: To describe the incidence and determinants of methicillin resistant and methicillin sensitive Staphylococcus aureus (MRSA and MSSA) bacteraemia in patients presenting to acute hospitals. Methicillin 57-68 solute carrier family 9 member A6 Homo sapiens 128-132 16155048-1 2005 OBJECTIVE: To describe the incidence and determinants of methicillin resistant and methicillin sensitive Staphylococcus aureus (MRSA and MSSA) bacteraemia in patients presenting to acute hospitals. Methicillin 83-94 solute carrier family 9 member A6 Homo sapiens 128-132 15681583-0 2005 In vivo synergy of daptomycin plus a penicillin agent for MRSA? Daptomycin 19-29 solute carrier family 9 member A6 Homo sapiens 58-62 15986222-2 2005 Treatment options for infections with MRSA are extremely limited because of resistance to all beta-lactam antibiotics and primarily because of the fast acquisition of further antibiotic resistance. beta-Lactams 94-105 solute carrier family 9 member A6 Homo sapiens 38-42 15834098-6 2005 CONCLUSION: Moxifloxacin penetrates well into the anterior chamber of the human uninflamed eye after oral administration, reaching early significant levels, which are maintained for at least 12 hours and are much higher than the MIC(90) values of Gram positive and Gram negative pathogens commonly implicated in intraocular infections with the exceptions of fluoroquinolone resistant staphylococci, MRSA, and Pseudomonas aeruginosa. Moxifloxacin 12-24 solute carrier family 9 member A6 Homo sapiens 399-403 16094598-0 2005 Efficacy of vancomycin-impregnated cement beads for the treatment of MRSA infection of failed graft tissue at the mandible. Vancomycin 12-22 solute carrier family 9 member A6 Homo sapiens 69-73 15922531-1 2005 OBJECTIVE: The methicillin resistance of Staphylococcus aureus MRSA is a major problem for human infections. Methicillin 15-26 solute carrier family 9 member A6 Homo sapiens 63-67 15681583-0 2005 In vivo synergy of daptomycin plus a penicillin agent for MRSA? Penicillins 37-47 solute carrier family 9 member A6 Homo sapiens 58-62 15320440-1 2004 DISTURBING EPIDEMIOLOGICAL DATA: Over the past decade there has been a continuous progression in the percentage of Staphylococcus aureus strains resistant to methicillin (MRSA), a slight progression in coagulase-negative staphylococci strains resistant to methicillin and a spectacular progression of enterococci resistant to glycopeptides, not only in hospitals but also in intensive care settings. Methicillin 158-169 solute carrier family 9 member A6 Homo sapiens 171-175 16400877-9 2005 The 1100 MRSA isolates distributed to four antibiotic resistance patterns on the basis of their resistance to oxacillin, penicillin, amoxicillin+clavulanic acid, azithromycin, clindamycin, amikacin, gentamicin, ciprofloxacin, trimethoprim+sulphamethoxasole, vancomycin and teicoplanin. Oxacillin 110-119 solute carrier family 9 member A6 Homo sapiens 9-13 16400877-9 2005 The 1100 MRSA isolates distributed to four antibiotic resistance patterns on the basis of their resistance to oxacillin, penicillin, amoxicillin+clavulanic acid, azithromycin, clindamycin, amikacin, gentamicin, ciprofloxacin, trimethoprim+sulphamethoxasole, vancomycin and teicoplanin. Penicillins 121-131 solute carrier family 9 member A6 Homo sapiens 9-13 16400877-9 2005 The 1100 MRSA isolates distributed to four antibiotic resistance patterns on the basis of their resistance to oxacillin, penicillin, amoxicillin+clavulanic acid, azithromycin, clindamycin, amikacin, gentamicin, ciprofloxacin, trimethoprim+sulphamethoxasole, vancomycin and teicoplanin. Amoxicillin-Potassium Clavulanate Combination 133-160 solute carrier family 9 member A6 Homo sapiens 9-13 16400877-9 2005 The 1100 MRSA isolates distributed to four antibiotic resistance patterns on the basis of their resistance to oxacillin, penicillin, amoxicillin+clavulanic acid, azithromycin, clindamycin, amikacin, gentamicin, ciprofloxacin, trimethoprim+sulphamethoxasole, vancomycin and teicoplanin. Azithromycin 162-174 solute carrier family 9 member A6 Homo sapiens 9-13 16400877-9 2005 The 1100 MRSA isolates distributed to four antibiotic resistance patterns on the basis of their resistance to oxacillin, penicillin, amoxicillin+clavulanic acid, azithromycin, clindamycin, amikacin, gentamicin, ciprofloxacin, trimethoprim+sulphamethoxasole, vancomycin and teicoplanin. Amikacin 189-197 solute carrier family 9 member A6 Homo sapiens 9-13 16400877-9 2005 The 1100 MRSA isolates distributed to four antibiotic resistance patterns on the basis of their resistance to oxacillin, penicillin, amoxicillin+clavulanic acid, azithromycin, clindamycin, amikacin, gentamicin, ciprofloxacin, trimethoprim+sulphamethoxasole, vancomycin and teicoplanin. Gentamicins 199-209 solute carrier family 9 member A6 Homo sapiens 9-13 16400877-9 2005 The 1100 MRSA isolates distributed to four antibiotic resistance patterns on the basis of their resistance to oxacillin, penicillin, amoxicillin+clavulanic acid, azithromycin, clindamycin, amikacin, gentamicin, ciprofloxacin, trimethoprim+sulphamethoxasole, vancomycin and teicoplanin. Ciprofloxacin 211-224 solute carrier family 9 member A6 Homo sapiens 9-13 16400877-9 2005 The 1100 MRSA isolates distributed to four antibiotic resistance patterns on the basis of their resistance to oxacillin, penicillin, amoxicillin+clavulanic acid, azithromycin, clindamycin, amikacin, gentamicin, ciprofloxacin, trimethoprim+sulphamethoxasole, vancomycin and teicoplanin. trimethoprim+sulphamethoxasole 226-256 solute carrier family 9 member A6 Homo sapiens 9-13 16400877-9 2005 The 1100 MRSA isolates distributed to four antibiotic resistance patterns on the basis of their resistance to oxacillin, penicillin, amoxicillin+clavulanic acid, azithromycin, clindamycin, amikacin, gentamicin, ciprofloxacin, trimethoprim+sulphamethoxasole, vancomycin and teicoplanin. Vancomycin 258-268 solute carrier family 9 member A6 Homo sapiens 9-13 16400877-9 2005 The 1100 MRSA isolates distributed to four antibiotic resistance patterns on the basis of their resistance to oxacillin, penicillin, amoxicillin+clavulanic acid, azithromycin, clindamycin, amikacin, gentamicin, ciprofloxacin, trimethoprim+sulphamethoxasole, vancomycin and teicoplanin. Teicoplanin 273-284 solute carrier family 9 member A6 Homo sapiens 9-13 16400877-10 2005 All the MRSA isolates were multidrug resistant but sensitive to glycopeptides. Glycopeptides 64-77 solute carrier family 9 member A6 Homo sapiens 8-12 15465268-0 2004 [Increased susceptibility to non-beta-lactam antimicrobial agents of MRSA isolates: relationship between genotype and antibiotype]. beta-Lactams 33-44 solute carrier family 9 member A6 Homo sapiens 69-73 15465268-5 2004 In contrast, the proportion of MRSA susceptible to erythromycin progressively increased from 7.0% to 32.5% (P < 0.001). Erythromycin 51-63 solute carrier family 9 member A6 Homo sapiens 31-35 15465268-10 2004 The increase of erythromycin-susceptibility within MRSA was caused by the emergence of clone C. Non-epidemic strains were more frequently susceptible to ofloxacin (31.8% vs. 1.1%) and tobramycin (45.4% vs. 16.8%) than epidemic strains. Erythromycin 16-28 solute carrier family 9 member A6 Homo sapiens 51-55 15350720-0 2004 The value of using chlorhexidine soap in a controlled trial to eradicate MRSA in colonized patients. Chlorhexidine 19-32 solute carrier family 9 member A6 Homo sapiens 73-77 15320440-1 2004 DISTURBING EPIDEMIOLOGICAL DATA: Over the past decade there has been a continuous progression in the percentage of Staphylococcus aureus strains resistant to methicillin (MRSA), a slight progression in coagulase-negative staphylococci strains resistant to methicillin and a spectacular progression of enterococci resistant to glycopeptides, not only in hospitals but also in intensive care settings. Methicillin 256-267 solute carrier family 9 member A6 Homo sapiens 171-175 15320440-1 2004 DISTURBING EPIDEMIOLOGICAL DATA: Over the past decade there has been a continuous progression in the percentage of Staphylococcus aureus strains resistant to methicillin (MRSA), a slight progression in coagulase-negative staphylococci strains resistant to methicillin and a spectacular progression of enterococci resistant to glycopeptides, not only in hospitals but also in intensive care settings. Glycopeptides 326-339 solute carrier family 9 member A6 Homo sapiens 171-175 15320441-2 2004 THE IMPACT OF MRSA INFECTIONS: Is clinical to start, with a greater mortality rate in MRSA bacteremias than in staphylococcal sensitive, in vancomycin-resistant enterococcal infections than in enterococcal sensitive infections, and in acquired pneumonia under mechanical ventilation. Vancomycin 140-150 solute carrier family 9 member A6 Homo sapiens 14-18 15175106-12 2004 CONCLUSIONS: Progressive eradication of MRSA carriage was observed with the antiseptic soap and mupirocin. Mupirocin 96-105 solute carrier family 9 member A6 Homo sapiens 40-44 15311566-4 2004 There has been an alarming rise in the incidence of MRSA, which has jumped from a reported 2% in 1992 to about 42% in 2001 in England & Wales. Adenosine Monophosphate 135-138 solute carrier family 9 member A6 Homo sapiens 52-56 15311566-5 2004 Use of antibiotic may lead to emergence of MRSA in debilitated patients requiring PEG feeding. Polyethylene Glycols 82-85 solute carrier family 9 member A6 Homo sapiens 43-47 14767588-0 2004 Linezolid in VAP by MRSA: a better choice? Linezolid 0-9 solute carrier family 9 member A6 Homo sapiens 20-24 17642608-0 2004 Silver sulphadiazine for MRSA infections. Silver Sulfadiazine 0-20 solute carrier family 9 member A6 Homo sapiens 25-29 14574840-2 2003 In order to apply chemiluminescent assay to detection of MRSA, we compared MIC and antimicrobial susceptibility to MPIPC in using chemiluminescent assay with these in using broth microdilution method. mpipc 115-120 solute carrier family 9 member A6 Homo sapiens 57-61 15449791-14 2003 For those infections acquired in the hospital therapy with third or fourth generation cephalosporins, carbapenems, beta-lactams with betalactamase inhibitors alone or in combination with an aminoglucoside and or vancomycin if MRSA is suspected is accepted therapy. Cephalosporins 86-100 solute carrier family 9 member A6 Homo sapiens 226-230 15449791-14 2003 For those infections acquired in the hospital therapy with third or fourth generation cephalosporins, carbapenems, beta-lactams with betalactamase inhibitors alone or in combination with an aminoglucoside and or vancomycin if MRSA is suspected is accepted therapy. beta-Lactams 115-127 solute carrier family 9 member A6 Homo sapiens 226-230 15449791-14 2003 For those infections acquired in the hospital therapy with third or fourth generation cephalosporins, carbapenems, beta-lactams with betalactamase inhibitors alone or in combination with an aminoglucoside and or vancomycin if MRSA is suspected is accepted therapy. Vancomycin 212-222 solute carrier family 9 member A6 Homo sapiens 226-230 14572485-4 2003 There were five patients from whom methicillin-sensitive S. aureus (MRSA) could be detected in oral specimens. Methicillin 35-46 solute carrier family 9 member A6 Homo sapiens 68-72 14572485-7 2003 There were five patients from whom methicillin-sensitive S. aureus (MRSA) could be detected in the oral specimens. Methicillin 35-46 solute carrier family 9 member A6 Homo sapiens 68-72 14510247-11 2003 CONCLUSION: Through multivariate modeling techniques, we were able to identify the most important determinants of MRSA at our institution and develop a tool to predict the probability of methicillin resistance in a patient with SAB. sab 228-231 solute carrier family 9 member A6 Homo sapiens 114-118 14564255-4 2003 Following the dehiscence of the thoracotomy surgical wound, a severe infective clinical picture, sustained by methicillin-resistant S. Aureus (MRSA), became evident with a diagnosis of bacterial endocarditis involving the aortic, mitral and tricuspid valves and caused the patient"s death due to septic shock complicated by ARDS. Methicillin 110-121 solute carrier family 9 member A6 Homo sapiens 143-147 12594655-0 2003 Persistent MRSA bacteremia in a patient with low linezolid levels. Linezolid 49-58 solute carrier family 9 member A6 Homo sapiens 11-15 12617235-7 2002 Gentamicin is active against more than 95% of MRSA strains cultured in our hospital and against 87% of MRSA strains cultured in the neurosurgery unit. Gentamicins 0-10 solute carrier family 9 member A6 Homo sapiens 46-50 12623326-1 2003 We investigated the effects of inhalation of tea catechin on MRSA in the 24 elderly in patients, who were known to carry MRSA in sputum. Catechin 49-57 solute carrier family 9 member A6 Homo sapiens 61-65 12623326-4 2003 After a week of the course, the numbers of the patients with decreased or disappearance of MRSA in their sputum was significantly higher in the catechin group, compared with that in the control group (seven vs. no patients; P<0.05). Catechin 144-152 solute carrier family 9 member A6 Homo sapiens 91-95 12623326-8 2003 Catechin inhalation seemed to be safe, and at least temporarily effective in the reduction of MRSA and shortening of hospitalization. Catechin 0-8 solute carrier family 9 member A6 Homo sapiens 94-98 12493811-0 2003 Susceptibility of MRSA to triclosan. Triclosan 26-35 solute carrier family 9 member A6 Homo sapiens 18-22 12617235-8 2002 A number-needed-to-treat (NNT) analysis showed that, with MRSA prevalence at 15%, cefuroxime plus gentamicin at induction could prevent one MRSA infection per 421 treated patients compared with cefuroxime alone. Gentamicins 98-108 solute carrier family 9 member A6 Homo sapiens 58-62 12617235-8 2002 A number-needed-to-treat (NNT) analysis showed that, with MRSA prevalence at 15%, cefuroxime plus gentamicin at induction could prevent one MRSA infection per 421 treated patients compared with cefuroxime alone. Gentamicins 98-108 solute carrier family 9 member A6 Homo sapiens 140-144 12617235-7 2002 Gentamicin is active against more than 95% of MRSA strains cultured in our hospital and against 87% of MRSA strains cultured in the neurosurgery unit. Gentamicins 0-10 solute carrier family 9 member A6 Homo sapiens 103-107 12617235-12 2002 Vancomycin can be reserved for patients known to be colonized with MRSA (NNT: 51). Vancomycin 0-10 solute carrier family 9 member A6 Homo sapiens 67-71 12617235-8 2002 A number-needed-to-treat (NNT) analysis showed that, with MRSA prevalence at 15%, cefuroxime plus gentamicin at induction could prevent one MRSA infection per 421 treated patients compared with cefuroxime alone. Cefuroxime 82-92 solute carrier family 9 member A6 Homo sapiens 58-62 12617235-8 2002 A number-needed-to-treat (NNT) analysis showed that, with MRSA prevalence at 15%, cefuroxime plus gentamicin at induction could prevent one MRSA infection per 421 treated patients compared with cefuroxime alone. Cefuroxime 82-92 solute carrier family 9 member A6 Homo sapiens 140-144 11913373-0 2002 Incidence of pseudomembranous colitis after vancomycin-treated MRSA infection. Vancomycin 44-54 solute carrier family 9 member A6 Homo sapiens 63-67 10452645-5 1999 In a multivariate linear regression model, rates of MRSA, central line-associated bloodstream infection, and the type of ICU were independent predictors of vancomycin use. Vancomycin 156-166 solute carrier family 9 member A6 Homo sapiens 52-56 11828710-6 2001 Vancomycin or teicoplanin is selected when MRSA or Enterococcus faecium infection is suspected. Vancomycin 0-10 solute carrier family 9 member A6 Homo sapiens 43-47 11828710-6 2001 Vancomycin or teicoplanin is selected when MRSA or Enterococcus faecium infection is suspected. Teicoplanin 14-25 solute carrier family 9 member A6 Homo sapiens 43-47 11675980-8 2001 However, there is also reason for concern about the recent emergence of MRSA resistant to glycopeptides, such as vancomycin. Glycopeptides 90-103 solute carrier family 9 member A6 Homo sapiens 72-76 11675980-8 2001 However, there is also reason for concern about the recent emergence of MRSA resistant to glycopeptides, such as vancomycin. Vancomycin 113-123 solute carrier family 9 member A6 Homo sapiens 72-76 11357444-8 2001 The methicillin (oxacillin)-resistant S. aureus (MRSA, ORSA) stems usually present the phenomenon of multiresistance, i.e. the resistance towards substances of several classes of antibiotics, and, therefore, are not only resistant to all beta-lactamantibiotics (penicillins, cephalosporins, carbapenems). Oxacillin 17-26 solute carrier family 9 member A6 Homo sapiens 49-53 11357444-8 2001 The methicillin (oxacillin)-resistant S. aureus (MRSA, ORSA) stems usually present the phenomenon of multiresistance, i.e. the resistance towards substances of several classes of antibiotics, and, therefore, are not only resistant to all beta-lactamantibiotics (penicillins, cephalosporins, carbapenems). Monobactams 238-260 solute carrier family 9 member A6 Homo sapiens 49-53 11357444-8 2001 The methicillin (oxacillin)-resistant S. aureus (MRSA, ORSA) stems usually present the phenomenon of multiresistance, i.e. the resistance towards substances of several classes of antibiotics, and, therefore, are not only resistant to all beta-lactamantibiotics (penicillins, cephalosporins, carbapenems). Penicillins 262-273 solute carrier family 9 member A6 Homo sapiens 49-53 11357444-8 2001 The methicillin (oxacillin)-resistant S. aureus (MRSA, ORSA) stems usually present the phenomenon of multiresistance, i.e. the resistance towards substances of several classes of antibiotics, and, therefore, are not only resistant to all beta-lactamantibiotics (penicillins, cephalosporins, carbapenems). Cephalosporins 275-289 solute carrier family 9 member A6 Homo sapiens 49-53 11357444-8 2001 The methicillin (oxacillin)-resistant S. aureus (MRSA, ORSA) stems usually present the phenomenon of multiresistance, i.e. the resistance towards substances of several classes of antibiotics, and, therefore, are not only resistant to all beta-lactamantibiotics (penicillins, cephalosporins, carbapenems). Carbapenems 291-302 solute carrier family 9 member A6 Homo sapiens 49-53 11249127-5 2001 Quinone methide 7 showed the most potent activity with 0.5-1 microg/mL of MIC against both MRSA and VRE. quinone 0-7 solute carrier family 9 member A6 Homo sapiens 91-95 11249127-5 2001 Quinone methide 7 showed the most potent activity with 0.5-1 microg/mL of MIC against both MRSA and VRE. methide 7 8-17 solute carrier family 9 member A6 Homo sapiens 91-95 11354818-4 2000 All the MRSA isolates in India including in the present study were sensitive to vancomycin and resistance to netilmycin appears to be low among MRSA isolates in India. Vancomycin 80-90 solute carrier family 9 member A6 Homo sapiens 8-12 11354818-4 2000 All the MRSA isolates in India including in the present study were sensitive to vancomycin and resistance to netilmycin appears to be low among MRSA isolates in India. Netilmicin 109-119 solute carrier family 9 member A6 Homo sapiens 8-12 11354818-4 2000 All the MRSA isolates in India including in the present study were sensitive to vancomycin and resistance to netilmycin appears to be low among MRSA isolates in India. Netilmicin 109-119 solute carrier family 9 member A6 Homo sapiens 144-148 11354818-5 2000 All the MRSA isolates were also found to be sensitive to teicoplanin in the present study. Teicoplanin 57-68 solute carrier family 9 member A6 Homo sapiens 8-12 11354818-6 2000 Like in other Indian studies, resistance to cotrimoxazole, erythromycin, gentamicin, other penicillins and cephalosporins appeared to be a common feature for MRSA isolates in the present study. Trimethoprim, Sulfamethoxazole Drug Combination 44-57 solute carrier family 9 member A6 Homo sapiens 158-162 11354818-6 2000 Like in other Indian studies, resistance to cotrimoxazole, erythromycin, gentamicin, other penicillins and cephalosporins appeared to be a common feature for MRSA isolates in the present study. Erythromycin 59-71 solute carrier family 9 member A6 Homo sapiens 158-162 11354818-6 2000 Like in other Indian studies, resistance to cotrimoxazole, erythromycin, gentamicin, other penicillins and cephalosporins appeared to be a common feature for MRSA isolates in the present study. Gentamicins 73-83 solute carrier family 9 member A6 Homo sapiens 158-162 11354818-6 2000 Like in other Indian studies, resistance to cotrimoxazole, erythromycin, gentamicin, other penicillins and cephalosporins appeared to be a common feature for MRSA isolates in the present study. Penicillins 91-102 solute carrier family 9 member A6 Homo sapiens 158-162 11354818-6 2000 Like in other Indian studies, resistance to cotrimoxazole, erythromycin, gentamicin, other penicillins and cephalosporins appeared to be a common feature for MRSA isolates in the present study. Cephalosporins 107-121 solute carrier family 9 member A6 Homo sapiens 158-162 10998878-0 2000 [The influence of the use of mupirocin nasal ointment on the incidence of endogenous MRSA infections in an intensive care unit]. Mupirocin 29-38 solute carrier family 9 member A6 Homo sapiens 85-89 10998878-3 2000 To evaluate the impact of mupirocin use on the incidence of endogenous infection caused by MRSA in an intensive care unit, we prospectively treated all patients in the unit with mupirocin, 3 times daily for 3 days. Mupirocin 26-35 solute carrier family 9 member A6 Homo sapiens 91-95 10998878-4 2000 This routine use of mupirocin led to eradication of nasal MRSA carriage in 81.8% of surveillance cultures and to a significant reduction in the total incidence of MRSA infection among MRSA carrier patients (0 episode in 11 patients) when compared to historical controls prior to the use of mupirocin (3 episodes in 7 patients). Mupirocin 20-29 solute carrier family 9 member A6 Homo sapiens 58-62 10998878-4 2000 This routine use of mupirocin led to eradication of nasal MRSA carriage in 81.8% of surveillance cultures and to a significant reduction in the total incidence of MRSA infection among MRSA carrier patients (0 episode in 11 patients) when compared to historical controls prior to the use of mupirocin (3 episodes in 7 patients). Mupirocin 20-29 solute carrier family 9 member A6 Homo sapiens 163-167 10998878-4 2000 This routine use of mupirocin led to eradication of nasal MRSA carriage in 81.8% of surveillance cultures and to a significant reduction in the total incidence of MRSA infection among MRSA carrier patients (0 episode in 11 patients) when compared to historical controls prior to the use of mupirocin (3 episodes in 7 patients). Mupirocin 20-29 solute carrier family 9 member A6 Homo sapiens 163-167 10923284-8 2000 Vancomycin (VCM) and arbekacin (ABK) showed the most potent activities against MRSA. Vancomycin 0-10 solute carrier family 9 member A6 Homo sapiens 79-83 10923284-8 2000 Vancomycin (VCM) and arbekacin (ABK) showed the most potent activities against MRSA. Vancomycin 12-15 solute carrier family 9 member A6 Homo sapiens 79-83 10923284-8 2000 Vancomycin (VCM) and arbekacin (ABK) showed the most potent activities against MRSA. arbekacin 21-30 solute carrier family 9 member A6 Homo sapiens 79-83 10522713-0 1999 2-Naphthylcarbapenems: broad spectrum antibiotics with enhanced potency against MRSA. 2-naphthylcarbapenems 0-21 solute carrier family 9 member A6 Homo sapiens 80-84 10565121-1 1999 Eleven clinical strains of MRSA which were detected as heterogeneously-resistant to vancomycin (hetero-VRSA) on Mu3-medium (a newly devised hetero-VRSA detecting medium) were subjected to a study to explore the therapeutic possibility of combination therapy. Vancomycin 84-94 solute carrier family 9 member A6 Homo sapiens 27-31 10565121-1 1999 Eleven clinical strains of MRSA which were detected as heterogeneously-resistant to vancomycin (hetero-VRSA) on Mu3-medium (a newly devised hetero-VRSA detecting medium) were subjected to a study to explore the therapeutic possibility of combination therapy. mu3-medium 112-122 solute carrier family 9 member A6 Homo sapiens 27-31 11357444-8 2001 The methicillin (oxacillin)-resistant S. aureus (MRSA, ORSA) stems usually present the phenomenon of multiresistance, i.e. the resistance towards substances of several classes of antibiotics, and, therefore, are not only resistant to all beta-lactamantibiotics (penicillins, cephalosporins, carbapenems). Methicillin 4-15 solute carrier family 9 member A6 Homo sapiens 49-53 11249127-0 2001 Synthesis of variously oxidized abietane diterpenes and their antibacterial activities against MRSA and VRE. Abietanes 32-40 solute carrier family 9 member A6 Homo sapiens 95-99 11249127-0 2001 Synthesis of variously oxidized abietane diterpenes and their antibacterial activities against MRSA and VRE. Diterpenes 41-51 solute carrier family 9 member A6 Homo sapiens 95-99 11249127-2 2001 Antimicrobial activities of synthesized phenolic diterpenes and their related compounds against MRSA and VRE were evaluated. Diterpenes 49-59 solute carrier family 9 member A6 Homo sapiens 96-100 11249127-3 2001 Phenols (12-hydroxyabieta-8,11,13-trien-6-one 22 and 23), catechols (12 and 14) and taxodione 25 showed potent activity with 4-10 microg/mL of MIC against MRSA and 4-16 microg/mL of MIC against VRE. Phenols 0-7 solute carrier family 9 member A6 Homo sapiens 155-159 11249127-3 2001 Phenols (12-hydroxyabieta-8,11,13-trien-6-one 22 and 23), catechols (12 and 14) and taxodione 25 showed potent activity with 4-10 microg/mL of MIC against MRSA and 4-16 microg/mL of MIC against VRE. 12-hydroxyabieta-8,11,13-trien-6-one 9-45 solute carrier family 9 member A6 Homo sapiens 155-159 11249127-3 2001 Phenols (12-hydroxyabieta-8,11,13-trien-6-one 22 and 23), catechols (12 and 14) and taxodione 25 showed potent activity with 4-10 microg/mL of MIC against MRSA and 4-16 microg/mL of MIC against VRE. taxodione 84-93 solute carrier family 9 member A6 Homo sapiens 155-159 11206444-0 2001 New anti-MRSA cephalosporins with a basic aminopyridine at the C-7 position. Cephalosporins 14-28 solute carrier family 9 member A6 Homo sapiens 9-13 11206444-0 2001 New anti-MRSA cephalosporins with a basic aminopyridine at the C-7 position. basic aminopyridine 36-55 solute carrier family 9 member A6 Homo sapiens 9-13 11206444-1 2001 Incorporation of a basic aminopyridine into the C-7 position of 3-(amine-substituted arylthio)-3-norcephalosporins, as in 3, afforded high potency against MRSA and acceptable solubility for intravenous administration. basic aminopyridine 19-38 solute carrier family 9 member A6 Homo sapiens 155-159 11206444-1 2001 Incorporation of a basic aminopyridine into the C-7 position of 3-(amine-substituted arylthio)-3-norcephalosporins, as in 3, afforded high potency against MRSA and acceptable solubility for intravenous administration. 3-(amine-substituted arylthio)-3-norcephalosporins 64-114 solute carrier family 9 member A6 Homo sapiens 155-159 11234220-0 2000 [Combination effect of teicoplanin and beta-lactams on MRSA]. Teicoplanin 23-34 solute carrier family 9 member A6 Homo sapiens 55-60 11234220-0 2000 [Combination effect of teicoplanin and beta-lactams on MRSA]. beta-Lactams 39-51 solute carrier family 9 member A6 Homo sapiens 55-60 11144420-5 2000 The overall frequency of drug resistance traits among the 1,749 MRSA strains was high (over 70% and up to and over 90% of the strains) to ciprofloxacin, erythromycin, clindamycin, gentamicin, and tetracycline, and was somewhat less frequent to sulfamethoxazole-trimethoprim (45%), chloramphenicol (30%), and rifampin (38%). Ciprofloxacin 138-151 solute carrier family 9 member A6 Homo sapiens 64-68 11144420-5 2000 The overall frequency of drug resistance traits among the 1,749 MRSA strains was high (over 70% and up to and over 90% of the strains) to ciprofloxacin, erythromycin, clindamycin, gentamicin, and tetracycline, and was somewhat less frequent to sulfamethoxazole-trimethoprim (45%), chloramphenicol (30%), and rifampin (38%). Erythromycin 153-165 solute carrier family 9 member A6 Homo sapiens 64-68 11144420-5 2000 The overall frequency of drug resistance traits among the 1,749 MRSA strains was high (over 70% and up to and over 90% of the strains) to ciprofloxacin, erythromycin, clindamycin, gentamicin, and tetracycline, and was somewhat less frequent to sulfamethoxazole-trimethoprim (45%), chloramphenicol (30%), and rifampin (38%). Clindamycin 167-178 solute carrier family 9 member A6 Homo sapiens 64-68 11144420-5 2000 The overall frequency of drug resistance traits among the 1,749 MRSA strains was high (over 70% and up to and over 90% of the strains) to ciprofloxacin, erythromycin, clindamycin, gentamicin, and tetracycline, and was somewhat less frequent to sulfamethoxazole-trimethoprim (45%), chloramphenicol (30%), and rifampin (38%). Gentamicins 180-190 solute carrier family 9 member A6 Homo sapiens 64-68 11144420-5 2000 The overall frequency of drug resistance traits among the 1,749 MRSA strains was high (over 70% and up to and over 90% of the strains) to ciprofloxacin, erythromycin, clindamycin, gentamicin, and tetracycline, and was somewhat less frequent to sulfamethoxazole-trimethoprim (45%), chloramphenicol (30%), and rifampin (38%). Tetracycline 196-208 solute carrier family 9 member A6 Homo sapiens 64-68 11144420-5 2000 The overall frequency of drug resistance traits among the 1,749 MRSA strains was high (over 70% and up to and over 90% of the strains) to ciprofloxacin, erythromycin, clindamycin, gentamicin, and tetracycline, and was somewhat less frequent to sulfamethoxazole-trimethoprim (45%), chloramphenicol (30%), and rifampin (38%). Trimethoprim, Sulfamethoxazole Drug Combination 244-273 solute carrier family 9 member A6 Homo sapiens 64-68 11144420-5 2000 The overall frequency of drug resistance traits among the 1,749 MRSA strains was high (over 70% and up to and over 90% of the strains) to ciprofloxacin, erythromycin, clindamycin, gentamicin, and tetracycline, and was somewhat less frequent to sulfamethoxazole-trimethoprim (45%), chloramphenicol (30%), and rifampin (38%). Chloramphenicol 281-296 solute carrier family 9 member A6 Homo sapiens 64-68 11144420-5 2000 The overall frequency of drug resistance traits among the 1,749 MRSA strains was high (over 70% and up to and over 90% of the strains) to ciprofloxacin, erythromycin, clindamycin, gentamicin, and tetracycline, and was somewhat less frequent to sulfamethoxazole-trimethoprim (45%), chloramphenicol (30%), and rifampin (38%). Rifampin 308-316 solute carrier family 9 member A6 Homo sapiens 64-68 10998878-5 2000 Mupirocin nasal ointment was significantly effective to prevent endogenous MRSA infection. Mupirocin 0-9 solute carrier family 9 member A6 Homo sapiens 75-79 10631792-0 1999 Eradication of MRSA from carriers by means of whole-body washing with an antiseptic in combination with mupirocin nasal ointment. Mupirocin 104-113 solute carrier family 9 member A6 Homo sapiens 15-19 10631792-10 1999 The study confirms that MRSA can be eradicated by means of washing with an antiseptic combined with mupirocin treatment. Mupirocin 100-109 solute carrier family 9 member A6 Homo sapiens 24-28 10563691-1 1999 Rifampicin has been successfully used as an adjunct to vancomycin therapy in several clinical conditions of MRSA infections such as endocarditis, ventriculoperitoneal shunts and septicaemia. Rifampin 0-10 solute carrier family 9 member A6 Homo sapiens 108-112 10563691-1 1999 Rifampicin has been successfully used as an adjunct to vancomycin therapy in several clinical conditions of MRSA infections such as endocarditis, ventriculoperitoneal shunts and septicaemia. Vancomycin 55-65 solute carrier family 9 member A6 Homo sapiens 108-112 10563691-3 1999 The present prospective study was conducted to evaluate the efficacy of rifampicin as an adjunct therapy in burn cases with MRSA septicaemia not responding well to vancomycin. Rifampin 72-82 solute carrier family 9 member A6 Homo sapiens 124-128 10563691-11 1999 Institution of rifampicin, as an adjunct to vancomycin therapy to which the MRSA isolates were susceptible, showed a dramatic clinical response and survival of grafts. Rifampin 15-25 solute carrier family 9 member A6 Homo sapiens 76-80 10563691-11 1999 Institution of rifampicin, as an adjunct to vancomycin therapy to which the MRSA isolates were susceptible, showed a dramatic clinical response and survival of grafts. Vancomycin 44-54 solute carrier family 9 member A6 Homo sapiens 76-80 10563691-13 1999 The present study thus confirms the efficacy of clinical use of rifampicin as an adjunct in vancomycin nonresponding cases of MRSA septicaemia in burns. Rifampin 64-74 solute carrier family 9 member A6 Homo sapiens 126-130 10565121-11 1999 It is known that MRSA is relatively easy to emerge resistance to teicoplanin. Teicoplanin 65-76 solute carrier family 9 member A6 Homo sapiens 17-21 10565121-13 1999 However, in a combination with beta-lactam antibiotics, teicoplanin appeared to be a promising agent for the treatment of MRSA infection. Teicoplanin 56-67 solute carrier family 9 member A6 Homo sapiens 122-126 10423963-3 1999 As the control of bacteria and the surgical intervention are both important in the treatment of pyothorax cases, we tried to reduce MRSA by washing with Povidone-Iodine solution through the drain. Povidone-Iodine 153-168 solute carrier family 9 member A6 Homo sapiens 132-136 10423963-6 1999 During the operation we frequently used acidic electrolyzed NaCl solution against MRSA. nacl solution 60-73 solute carrier family 9 member A6 Homo sapiens 82-86 10423963-7 1999 For one month after the operation, we used Vancomycin which is effective against MRSA, however, rather severe side effects were seen, and finally and MRSA vanished. Vancomycin 43-53 solute carrier family 9 member A6 Homo sapiens 81-85 10423963-7 1999 For one month after the operation, we used Vancomycin which is effective against MRSA, however, rather severe side effects were seen, and finally and MRSA vanished. Vancomycin 43-53 solute carrier family 9 member A6 Homo sapiens 150-154 10452645-7 1999 Vancomycin use is heavily determined by rates of endemic MRSA and central line-associated bloodstream infection. Vancomycin 0-10 solute carrier family 9 member A6 Homo sapiens 57-61 10326611-0 1999 New cases of vancomycin-intermediate MRSA infection reported. Vancomycin 13-23 solute carrier family 9 member A6 Homo sapiens 37-41 10063475-1 1999 We investigated the use of tube coagulase and a fluorescent substrate, N-t-BOC-val-pro-arg-7-amido-4-methylcoumarin for the rapid detection of MRSA in selective broth enrichment cultures during an outbreak. n-t-boc-val-pro-arg-7-amido-4-methylcoumarin 71-115 solute carrier family 9 member A6 Homo sapiens 143-147 9852643-1 1998 OBJECTIVES: To identify the attributed mortality rate of bloodstream hospital infection by Staphylococcus aureus resistant to methicillin (MRSA) and its effect on length of hospital stay. Methicillin 126-137 solute carrier family 9 member A6 Homo sapiens 139-143 10481526-7 1999 We suggest that local administration of vancomycin is an effective method in postpneumonectomy empyema with MRSA infection. Vancomycin 40-50 solute carrier family 9 member A6 Homo sapiens 108-112 9818969-3 1998 The I:E:F clonal type and a stable drug multidrug resistant phenotype (sensitivity only to trimethoprim/sulfamethoxazole and vancomycin) indicated that these isolates were closely related to the Iberian clone of MRSA, which is widely spread in Europe. Trimethoprim, Sulfamethoxazole Drug Combination 91-120 solute carrier family 9 member A6 Homo sapiens 212-216 9818969-3 1998 The I:E:F clonal type and a stable drug multidrug resistant phenotype (sensitivity only to trimethoprim/sulfamethoxazole and vancomycin) indicated that these isolates were closely related to the Iberian clone of MRSA, which is widely spread in Europe. Vancomycin 125-135 solute carrier family 9 member A6 Homo sapiens 212-216 9789363-10 1998 MRSA-strains were more resistant to imipenem, ofloxacin, gentamicin, trimethoprim-sulfamethoxazole, tetracycline, erythromycin and clindamycin as oxacillin-sensitive Straphylococcus aureus strains. Imipenem 36-44 solute carrier family 9 member A6 Homo sapiens 0-4 9789363-10 1998 MRSA-strains were more resistant to imipenem, ofloxacin, gentamicin, trimethoprim-sulfamethoxazole, tetracycline, erythromycin and clindamycin as oxacillin-sensitive Straphylococcus aureus strains. Ofloxacin 46-55 solute carrier family 9 member A6 Homo sapiens 0-4 9789363-10 1998 MRSA-strains were more resistant to imipenem, ofloxacin, gentamicin, trimethoprim-sulfamethoxazole, tetracycline, erythromycin and clindamycin as oxacillin-sensitive Straphylococcus aureus strains. Gentamicins 57-67 solute carrier family 9 member A6 Homo sapiens 0-4 9789363-10 1998 MRSA-strains were more resistant to imipenem, ofloxacin, gentamicin, trimethoprim-sulfamethoxazole, tetracycline, erythromycin and clindamycin as oxacillin-sensitive Straphylococcus aureus strains. Trimethoprim, Sulfamethoxazole Drug Combination 69-98 solute carrier family 9 member A6 Homo sapiens 0-4 9789363-10 1998 MRSA-strains were more resistant to imipenem, ofloxacin, gentamicin, trimethoprim-sulfamethoxazole, tetracycline, erythromycin and clindamycin as oxacillin-sensitive Straphylococcus aureus strains. Tetracycline 100-112 solute carrier family 9 member A6 Homo sapiens 0-4 9789363-10 1998 MRSA-strains were more resistant to imipenem, ofloxacin, gentamicin, trimethoprim-sulfamethoxazole, tetracycline, erythromycin and clindamycin as oxacillin-sensitive Straphylococcus aureus strains. Erythromycin 114-126 solute carrier family 9 member A6 Homo sapiens 0-4 9789363-10 1998 MRSA-strains were more resistant to imipenem, ofloxacin, gentamicin, trimethoprim-sulfamethoxazole, tetracycline, erythromycin and clindamycin as oxacillin-sensitive Straphylococcus aureus strains. Clindamycin 131-142 solute carrier family 9 member A6 Homo sapiens 0-4 9789363-10 1998 MRSA-strains were more resistant to imipenem, ofloxacin, gentamicin, trimethoprim-sulfamethoxazole, tetracycline, erythromycin and clindamycin as oxacillin-sensitive Straphylococcus aureus strains. Oxacillin 146-155 solute carrier family 9 member A6 Homo sapiens 0-4 12631818-1 1997 Strains of Staphylococcus aureusresistant to multiple antibiotics, including those resistant to methicillin (MRSA), present a major problem in the control of hospital acquired infections. Methicillin 96-107 solute carrier family 9 member A6 Homo sapiens 109-113 10681822-1 1998 MRSA and MRSE were identified by detecting oxacillin resistance of 107 strains of staphylococci from clinical sources. Oxacillin 43-52 solute carrier family 9 member A6 Homo sapiens 0-4 9373559-5 1997 Once MRSA had been identified they were treated with intravenous teicoplanin and all made a full recovery. Teicoplanin 65-76 solute carrier family 9 member A6 Homo sapiens 5-9 9259029-5 1997 In most Western countries with a relatively low incidence of MRSA, penicillin-derivatives, such as flucloxacillin (or cloxacillin, methicillin and nafcillin) will be the drug of choice, because of their good in-vitro activity, low toxicity, good clinical efficacy and relatively low cost. Penicillins 67-77 solute carrier family 9 member A6 Homo sapiens 61-65 9259029-5 1997 In most Western countries with a relatively low incidence of MRSA, penicillin-derivatives, such as flucloxacillin (or cloxacillin, methicillin and nafcillin) will be the drug of choice, because of their good in-vitro activity, low toxicity, good clinical efficacy and relatively low cost. Floxacillin 99-113 solute carrier family 9 member A6 Homo sapiens 61-65 9259029-5 1997 In most Western countries with a relatively low incidence of MRSA, penicillin-derivatives, such as flucloxacillin (or cloxacillin, methicillin and nafcillin) will be the drug of choice, because of their good in-vitro activity, low toxicity, good clinical efficacy and relatively low cost. Cloxacillin 102-113 solute carrier family 9 member A6 Homo sapiens 61-65 9259029-5 1997 In most Western countries with a relatively low incidence of MRSA, penicillin-derivatives, such as flucloxacillin (or cloxacillin, methicillin and nafcillin) will be the drug of choice, because of their good in-vitro activity, low toxicity, good clinical efficacy and relatively low cost. Methicillin 131-142 solute carrier family 9 member A6 Homo sapiens 61-65 9259029-5 1997 In most Western countries with a relatively low incidence of MRSA, penicillin-derivatives, such as flucloxacillin (or cloxacillin, methicillin and nafcillin) will be the drug of choice, because of their good in-vitro activity, low toxicity, good clinical efficacy and relatively low cost. Nafcillin 147-156 solute carrier family 9 member A6 Homo sapiens 61-65 9259029-6 1997 If the incidence of MRSA increases, drugs such as the glycopeptides will be of more importance. Glycopeptides 54-67 solute carrier family 9 member A6 Homo sapiens 20-24 8724815-2 1996 For example, there has been a sharp increase in the incidence of infections caused by Staphylococcus aureus, particularly those resistant to methicillin (MRSA), and methicillin-resistant coagulase-negative staphylococci, particularly those associated with foreign bodies and indwelling medical devices. Methicillin 141-152 solute carrier family 9 member A6 Homo sapiens 154-158 9192247-0 1997 [Effect of imipenem/cilastatin combined with vancomycin for MRSA infection]. Imipenem 11-19 solute carrier family 9 member A6 Homo sapiens 60-64 9192247-0 1997 [Effect of imipenem/cilastatin combined with vancomycin for MRSA infection]. Cilastatin 20-30 solute carrier family 9 member A6 Homo sapiens 60-64 9192247-0 1997 [Effect of imipenem/cilastatin combined with vancomycin for MRSA infection]. Vancomycin 45-55 solute carrier family 9 member A6 Homo sapiens 60-64 9192247-6 1997 The present results suggested that simultaneous use of IPM/CS and VCM at the standard doses could yield an enhancement of both bacteriological and clinical efficacies in treatment of the patients with MRSA infection. Cesium 59-61 solute carrier family 9 member A6 Homo sapiens 201-205 9594292-0 1997 Multiple antibiotic-resistant lactic acid bacteria preparation eliminated MRSA from the decubitus of a bed-ridden elderly patient. Lactic Acid 30-41 solute carrier family 9 member A6 Homo sapiens 74-78 9053533-0 1996 [Clinical studies on vancomycin in the treatment of MRSA infection]. Vancomycin 21-31 solute carrier family 9 member A6 Homo sapiens 52-56 9053533-7 1996 (1) In cases of single infection with MRSA, the rate of bacterial eradication was 71.4% (5/7) with VCM alone and 68.2% (30/44) with VCM in combination with beta-lactam antibiotics. beta-Lactams 156-167 solute carrier family 9 member A6 Homo sapiens 38-42 8752859-0 1996 [Management of MRSA-harboring patients: focused on mupirocin]. Mupirocin 51-60 solute carrier family 9 member A6 Homo sapiens 15-19 8072164-0 1994 [Special issue: Current state of MRSA infections and practical chemotherapy with arbekacin]. arbekacin 81-90 solute carrier family 9 member A6 Homo sapiens 33-37 7807691-2 1994 We conducted a multicenter trial to determine the clinical usefulness of the combined therapy with flomoxef (FMOX) and fosfomycin (FOM) (FF therapy) as an empirical therapy in the treatment of intractable respiratory tract infections, because FF therapy has clinically been proved to be very useful for the treatment of severe infections including MRSA infections. flomoxef 99-107 solute carrier family 9 member A6 Homo sapiens 348-352 7807691-2 1994 We conducted a multicenter trial to determine the clinical usefulness of the combined therapy with flomoxef (FMOX) and fosfomycin (FOM) (FF therapy) as an empirical therapy in the treatment of intractable respiratory tract infections, because FF therapy has clinically been proved to be very useful for the treatment of severe infections including MRSA infections. Fosfomycin 131-134 solute carrier family 9 member A6 Homo sapiens 348-352 8072168-18 1994 MRSA has become more resistant to methicillin however it seemed to have become less toxic. Methicillin 34-45 solute carrier family 9 member A6 Homo sapiens 0-4 8072181-0 1994 [Clinical efficacy of arbekacin on MRSA infections]. arbekacin 22-31 solute carrier family 9 member A6 Homo sapiens 35-39 8072181-1 1994 Clinical efficacy of arbekacin (ABK) was examined on patients with MRSA infection during hospitalization in Nagoya University Hospital. arbekacin 21-30 solute carrier family 9 member A6 Homo sapiens 67-71 8072182-1 1994 Niigata Research Group of MRSA.ABK]. niigata 0-7 solute carrier family 9 member A6 Homo sapiens 26-30 8072182-6 1994 These results are comparable with, or superior to the vancomycin therapy in the treatment of MRSA pneumonia. Vancomycin 54-64 solute carrier family 9 member A6 Homo sapiens 93-97 7791423-6 1995 Minocycline is the preferred drug for MRSA colonization/infection. Minocycline 0-11 solute carrier family 9 member A6 Homo sapiens 38-42 8549296-0 1995 Analysis of quinolone resistance genes in a clinical isolate of quinolone-resistant MRSA. Quinolones 12-21 solute carrier family 9 member A6 Homo sapiens 84-88 8549296-0 1995 Analysis of quinolone resistance genes in a clinical isolate of quinolone-resistant MRSA. Quinolones 64-73 solute carrier family 9 member A6 Homo sapiens 84-88 7806873-0 1994 Mupirocin-resistant MRSA. Mupirocin 0-9 solute carrier family 9 member A6 Homo sapiens 20-24 8151141-5 1994 Administration of antibiotics before isolation of Staphylococcus aureus were thought to be the most significant factor in producing the methicillin-resistant septicemia, used in 41% of MSSA and 91.3% of MRSA cases. Methicillin 136-147 solute carrier family 9 member A6 Homo sapiens 203-207 8129380-6 1994 For treatment of MRSA infections in patients with malignancy, a combination chemotherapy with vancomycin (VCM), or arbekacin (ABK) plus beta-lactam antibiotic is recommended, and granulocyte colony stimulating factor (G-CSF) is clinically useful when the granulocytopenia was induced by chemotherapy. Vancomycin 94-104 solute carrier family 9 member A6 Homo sapiens 17-21 8072185-0 1994 [Clinical efficacy of arbekacin on MRSA infections with hematopoietic disorders. arbekacin 22-31 solute carrier family 9 member A6 Homo sapiens 35-39 8072185-2 1994 Arbekacin (ABK) was administered to 17 patients with MRSA infections that complicated underlying hematopoietic disorders, and the efficacy and safety were evaluated. arbekacin 0-9 solute carrier family 9 member A6 Homo sapiens 53-57 8072185-11 1994 Arbekacin therapy was found to be effective even in patients with hematopoietic disorders accompanied by MRSA infections. arbekacin 0-9 solute carrier family 9 member A6 Homo sapiens 105-109 8072194-0 1994 [Clinical effect of arbekacin on MRSA infections after gastrointestinal surgery]. arbekacin 20-29 solute carrier family 9 member A6 Homo sapiens 33-37 8282584-0 1993 [Detection of MRSA in National Leprosarium of Ohshima Seisho-En]. ohshima seisho-en 46-63 solute carrier family 9 member A6 Homo sapiens 14-18 8195837-3 1993 The incidence of trimethoprim resistance is highly variable, depending upon methodology, type of patients, local epidemiology: this can be illustrated by the high variation of trimethoprim resistance among Salmonella, Shigella or MRSA in various countries and by the incidence of resistance in penicillin-resistant Streptococcus pneumoniae. Trimethoprim 17-29 solute carrier family 9 member A6 Homo sapiens 230-234 8195837-3 1993 The incidence of trimethoprim resistance is highly variable, depending upon methodology, type of patients, local epidemiology: this can be illustrated by the high variation of trimethoprim resistance among Salmonella, Shigella or MRSA in various countries and by the incidence of resistance in penicillin-resistant Streptococcus pneumoniae. Trimethoprim 176-188 solute carrier family 9 member A6 Homo sapiens 230-234 1293220-9 1992 Concerning the drug sensitivity, many MRSA strains were highly resistant to DMPPC and FOM, but the sensitivity to RFP was 0.1 microgram/ml or less in all strains except for one highly resistant strain (200 micrograms/ml or above). dmppc 76-81 solute carrier family 9 member A6 Homo sapiens 38-42 8320471-0 1993 [MICs of oxacillin for MRSA: a comparative study of strains from staff and patients]. Oxacillin 9-18 solute carrier family 9 member A6 Homo sapiens 23-27 8290904-6 1993 Virtually any agent will select MRSA and MRSE since the chromosomal location of the resistance of multiple-antibiotics makes such selection common and explains the rapid rate of the fluoroquinolones as therapy of MRSA. Fluoroquinolones 182-198 solute carrier family 9 member A6 Homo sapiens 32-36 8290904-6 1993 Virtually any agent will select MRSA and MRSE since the chromosomal location of the resistance of multiple-antibiotics makes such selection common and explains the rapid rate of the fluoroquinolones as therapy of MRSA. Fluoroquinolones 182-198 solute carrier family 9 member A6 Homo sapiens 213-217 1863618-10 1991 Our MRSA strain belong to phage type III, and shows a characteristic multiple antibiotic resistant pattern, the MRSA strain is sensitive to vancomycin, fusidic acid, phosphomycin and cotrimoxazole. Vancomycin 140-150 solute carrier family 9 member A6 Homo sapiens 4-8 1863618-10 1991 Our MRSA strain belong to phage type III, and shows a characteristic multiple antibiotic resistant pattern, the MRSA strain is sensitive to vancomycin, fusidic acid, phosphomycin and cotrimoxazole. Vancomycin 140-150 solute carrier family 9 member A6 Homo sapiens 112-116 1863618-10 1991 Our MRSA strain belong to phage type III, and shows a characteristic multiple antibiotic resistant pattern, the MRSA strain is sensitive to vancomycin, fusidic acid, phosphomycin and cotrimoxazole. Fusidic Acid 152-164 solute carrier family 9 member A6 Homo sapiens 4-8 1863618-10 1991 Our MRSA strain belong to phage type III, and shows a characteristic multiple antibiotic resistant pattern, the MRSA strain is sensitive to vancomycin, fusidic acid, phosphomycin and cotrimoxazole. Fusidic Acid 152-164 solute carrier family 9 member A6 Homo sapiens 112-116 1863618-10 1991 Our MRSA strain belong to phage type III, and shows a characteristic multiple antibiotic resistant pattern, the MRSA strain is sensitive to vancomycin, fusidic acid, phosphomycin and cotrimoxazole. Fosfomycin 166-178 solute carrier family 9 member A6 Homo sapiens 4-8 1863618-10 1991 Our MRSA strain belong to phage type III, and shows a characteristic multiple antibiotic resistant pattern, the MRSA strain is sensitive to vancomycin, fusidic acid, phosphomycin and cotrimoxazole. Fosfomycin 166-178 solute carrier family 9 member A6 Homo sapiens 112-116 1863618-10 1991 Our MRSA strain belong to phage type III, and shows a characteristic multiple antibiotic resistant pattern, the MRSA strain is sensitive to vancomycin, fusidic acid, phosphomycin and cotrimoxazole. Trimethoprim, Sulfamethoxazole Drug Combination 183-196 solute carrier family 9 member A6 Homo sapiens 4-8 1863618-10 1991 Our MRSA strain belong to phage type III, and shows a characteristic multiple antibiotic resistant pattern, the MRSA strain is sensitive to vancomycin, fusidic acid, phosphomycin and cotrimoxazole. Trimethoprim, Sulfamethoxazole Drug Combination 183-196 solute carrier family 9 member A6 Homo sapiens 112-116 1863618-11 1991 Over the entire outbreak period, the MRSA strain developed resistance to rifampin, imipenem-cilastatin and ciprofloxacin. Rifampin 73-81 solute carrier family 9 member A6 Homo sapiens 37-41 1863618-11 1991 Over the entire outbreak period, the MRSA strain developed resistance to rifampin, imipenem-cilastatin and ciprofloxacin. Cilastatin, Imipenem Drug Combination 83-102 solute carrier family 9 member A6 Homo sapiens 37-41 1863618-11 1991 Over the entire outbreak period, the MRSA strain developed resistance to rifampin, imipenem-cilastatin and ciprofloxacin. Ciprofloxacin 107-120 solute carrier family 9 member A6 Homo sapiens 37-41 2233663-0 1990 [Intravenous administration of vancomycin for postoperative MRSA infection and its pharmacokinetics: preliminary report]. Vancomycin 31-41 solute carrier family 9 member A6 Homo sapiens 60-64 1507428-3 1992 Arbekacin, a newly developed aminoglycoside antibiotic, showed more active than vancomycin to MRSA in vitro. arbekacin 0-9 solute carrier family 9 member A6 Homo sapiens 94-98 1507428-3 1992 Arbekacin, a newly developed aminoglycoside antibiotic, showed more active than vancomycin to MRSA in vitro. Vancomycin 80-90 solute carrier family 9 member A6 Homo sapiens 94-98 1507428-5 1992 Combined activity of arbekacin and vancomycin against 27 MRSA strains was evaluated by checkerboard technique. arbekacin 21-30 solute carrier family 9 member A6 Homo sapiens 57-61 1507428-5 1992 Combined activity of arbekacin and vancomycin against 27 MRSA strains was evaluated by checkerboard technique. Vancomycin 35-45 solute carrier family 9 member A6 Homo sapiens 57-61 1507434-5 1992 In a postoperative multiple trauma patient, with pneumonia, thoracic empyema, intraabdominal abscess, wound infection and sepsis caused by MRSA, surgical drainage of the abscess with systemic infusion of vancomycin was effective and resulted in full recovery. Vancomycin 204-214 solute carrier family 9 member A6 Homo sapiens 139-143 1507441-3 1992 Factors contributing to MRSA infections were mainly indwelling catheterization, preceding antimicrobial therapy (new quinolones and new cephems), and obstructive disease. Quinolones 117-127 solute carrier family 9 member A6 Homo sapiens 24-28 1507441-3 1992 Factors contributing to MRSA infections were mainly indwelling catheterization, preceding antimicrobial therapy (new quinolones and new cephems), and obstructive disease. cephems 136-143 solute carrier family 9 member A6 Homo sapiens 24-28 1507452-8 1992 As for drug susceptibility, MRSA strains with coagulase type VII were more sensitive to clindamycin and more resistant to minocyclin compared to MRSA with other coagulase types. Clindamycin 88-99 solute carrier family 9 member A6 Homo sapiens 28-32