PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 15771964-3 2005 To redirect the tropism of HSV-1, we have generated a soluble adapter protein (P-V528LH) comprising the gD-binding variable domain of nectin-1 fused to a single-chain antibody (528LH) recognizing the EGF receptor. Gadolinium 104-106 nectin-1 Cricetulus griseus 134-142 15507614-6 2004 (iii) Entry mediated by nectin1-EGFR1 was selectively inhibited by AG1478, a tyrosine phosphorylation inhibitor that targets the EGFR1 cytoplasmic tail and blocks the signaling pathway that culminates in clathrin-dependent uptake of the receptor into endosomes. RTKI cpd 67-73 nectin-1 Cricetulus griseus 24-31 15507614-6 2004 (iii) Entry mediated by nectin1-EGFR1 was selectively inhibited by AG1478, a tyrosine phosphorylation inhibitor that targets the EGFR1 cytoplasmic tail and blocks the signaling pathway that culminates in clathrin-dependent uptake of the receptor into endosomes. Tyrosine 77-85 nectin-1 Cricetulus griseus 24-31