PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
10970046-4	2000	For isolated ghost membranes, the apparent IC50 (the drug concentration that produces 50% inhibition of lipid peroxidation) in cumene hydroperoxide-induced peroxidation was 25 microM, while the maximum protective effect of RA-25 was around 30% in the drug concentration range of 50-100 microM.	cumene hydroperoxide	127-147	RA25	Homo sapiens	223-228
10970046-7	2000	On the other hand, RA-25 is more hydrophilic than DIP, binds to the membrane to a smaller extent, and, for this reason, has a lower antioxidant effect.	Dipyridamole	50-53	RA25	Homo sapiens	19-24
9315611-1	1997	Binding and localization of the vasodilator and antitumor drug coactivator dipyridamole (DIP) and one of its derivatives, RA25, to phospholipid vesicles of DMPC (dimyristoylphosphatidylcholine) and DPPC (dipalmitoylphosphatidylcholine) was studied using fluorescence spectroscopy as well as quenching of fluorescence.	Phospholipids	131-143	RA25	Homo sapiens	122-126
9315611-1	1997	Binding and localization of the vasodilator and antitumor drug coactivator dipyridamole (DIP) and one of its derivatives, RA25, to phospholipid vesicles of DMPC (dimyristoylphosphatidylcholine) and DPPC (dipalmitoylphosphatidylcholine) was studied using fluorescence spectroscopy as well as quenching of fluorescence.	Dimyristoylphosphatidylcholine	156-160	RA25	Homo sapiens	122-126
9315611-1	1997	Binding and localization of the vasodilator and antitumor drug coactivator dipyridamole (DIP) and one of its derivatives, RA25, to phospholipid vesicles of DMPC (dimyristoylphosphatidylcholine) and DPPC (dipalmitoylphosphatidylcholine) was studied using fluorescence spectroscopy as well as quenching of fluorescence.	Dimyristoylphosphatidylcholine	162-192	RA25	Homo sapiens	122-126
9315611-1	1997	Binding and localization of the vasodilator and antitumor drug coactivator dipyridamole (DIP) and one of its derivatives, RA25, to phospholipid vesicles of DMPC (dimyristoylphosphatidylcholine) and DPPC (dipalmitoylphosphatidylcholine) was studied using fluorescence spectroscopy as well as quenching of fluorescence.	1,2-Dipalmitoylphosphatidylcholine	198-202	RA25	Homo sapiens	122-126
9315611-1	1997	Binding and localization of the vasodilator and antitumor drug coactivator dipyridamole (DIP) and one of its derivatives, RA25, to phospholipid vesicles of DMPC (dimyristoylphosphatidylcholine) and DPPC (dipalmitoylphosphatidylcholine) was studied using fluorescence spectroscopy as well as quenching of fluorescence.	1,2-Dipalmitoylphosphatidylcholine	204-234	RA25	Homo sapiens	122-126
9315611-11	1997	In the case of RA25, the drug is in the outer part of the head group interface being much exposed to the aqueous phase and being significantly less accessible to the membrane nitroxide quenchers.	Hydroxylamine	175-184	RA25	Homo sapiens	15-19
8810098-3	1996	The binding constants for the neutral drug forms change in the same order in the range of 1400-3100 M-1 for DIP to 80-300 M-1 for RA25.	Dipyridamole	108-111	RA25	Homo sapiens	130-134
18028212-3	2007	In the present work, the quenching of singlet molecular oxygen, O(2)((1)Delta(g)), by DIP and RA47 and RA25 derivatives was analyzed in acetonitrile (ACN) and aqueous acid solutions.	Oxygen	56-62	RA25	Homo sapiens	103-107
18028212-3	2007	In the present work, the quenching of singlet molecular oxygen, O(2)((1)Delta(g)), by DIP and RA47 and RA25 derivatives was analyzed in acetonitrile (ACN) and aqueous acid solutions.	Oxygen	64-68	RA25	Homo sapiens	103-107
18028212-3	2007	In the present work, the quenching of singlet molecular oxygen, O(2)((1)Delta(g)), by DIP and RA47 and RA25 derivatives was analyzed in acetonitrile (ACN) and aqueous acid solutions.	acetonitrile	136-148	RA25	Homo sapiens	103-107
10320680-9	1999	The association constants for DIP and RA-25 in mitochondria were estimated, being 0.7 (mg/ml)-1 for DIP and 0.2 (mg/ml)-1 for RA-25.	Dipyridamole	30-33	RA25	Homo sapiens	126-131
10320680-9	1999	The association constants for DIP and RA-25 in mitochondria were estimated, being 0.7 (mg/ml)-1 for DIP and 0.2 (mg/ml)-1 for RA-25.	Dipyridamole	100-103	RA25	Homo sapiens	38-43
10320680-10	1999	Oxygen consumption studies in the presence of FeSO4 showed that the antioxidant effect of DIP or RA-25 did not involved the initial step of Fe2+ oxidation.	Oxygen	0-6	RA25	Homo sapiens	97-102
10320680-10	1999	Oxygen consumption studies in the presence of FeSO4 showed that the antioxidant effect of DIP or RA-25 did not involved the initial step of Fe2+ oxidation.	ferrous sulfate	46-51	RA25	Homo sapiens	97-102
9358248-7	1997	The order of hydrophobicity of the DIP derivatives, DIP > RA14 > RA47 > RA25, correlates very well with both the values of the association constants of these derivatives to micelles, their localization in the micelles, and phospholipid films and their antioxidant effect on mitochondria.	Dipyridamole	35-38	RA25	Homo sapiens	81-85
9358248-7	1997	The order of hydrophobicity of the DIP derivatives, DIP > RA14 > RA47 > RA25, correlates very well with both the values of the association constants of these derivatives to micelles, their localization in the micelles, and phospholipid films and their antioxidant effect on mitochondria.	Dipyridamole	52-55	RA25	Homo sapiens	81-85
9358248-7	1997	The order of hydrophobicity of the DIP derivatives, DIP > RA14 > RA47 > RA25, correlates very well with both the values of the association constants of these derivatives to micelles, their localization in the micelles, and phospholipid films and their antioxidant effect on mitochondria.	ra47	71-75	RA25	Homo sapiens	81-85
9358248-7	1997	The order of hydrophobicity of the DIP derivatives, DIP > RA14 > RA47 > RA25, correlates very well with both the values of the association constants of these derivatives to micelles, their localization in the micelles, and phospholipid films and their antioxidant effect on mitochondria.	Phospholipids	232-244	RA25	Homo sapiens	81-85