PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
17654484-7	2008	We show here that the ROCK kinase inhibitor Y27362 reduces migration on laminin and causes a loss of central focal adhesions, similarly as ICAP-1 knockdown.	y27362	44-50	integrin beta 1 binding protein 1	Mus musculus	139-145
11807099-1	2002	Using two-hybrid screening, we isolated the integrin cytoplasmic domain-associated protein (ICAP-1), an interactor for the COOH terminal region of the beta1A integrin cytoplasmic domain.	Carbonic Acid	123-127	integrin beta 1 binding protein 1	Mus musculus	92-98
16037064-5	2005	Analogous to the established interactions of CCM1 and beta1 integrin with ICAP1, the CCM1/CCM2 association is dependent upon the phosphotyrosine binding (PTB) domain of CCM2.	Phosphotyrosine	129-144	integrin beta 1 binding protein 1	Mus musculus	74-79
11807099-6	2002	In the attempt to define the molecular mechanism of this inhibition, we show that ICAP-1 reduces both the intrinsic and the exchange factor-induced dissociation of GDP from Cdc42; moreover, purified ICAP-1 displaces this GTPase from cellular membranes.	Guanosine Diphosphate	164-167	integrin beta 1 binding protein 1	Mus musculus	82-88
11807099-6	2002	In the attempt to define the molecular mechanism of this inhibition, we show that ICAP-1 reduces both the intrinsic and the exchange factor-induced dissociation of GDP from Cdc42; moreover, purified ICAP-1 displaces this GTPase from cellular membranes.	Guanosine Diphosphate	164-167	integrin beta 1 binding protein 1	Mus musculus	199-205
11807099-7	2002	Together, these data show for the first time that ICAP-1 regulates Rho family GTPases during integrin-mediated cell matrix adhesion, acting as guanine dissociation inhibitor.	Guanine	143-150	integrin beta 1 binding protein 1	Mus musculus	50-56