PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 20301759-6 1993 MANAGEMENT: Treatment of manifestations: Intramuscular or subcutaneous injections of interferon (IFN)-alpha2a or INF-alpha2b given two or three times a week increase hemoglobin and decrease iron overload in the majority of treated individuals. Iron 190-194 interferon alpha 17 Homo sapiens 113-122 31995552-5 2020 Conversely, the InfA mRNA allowed ppGpp to compete with GTP for IF2, thus stalling 30S complexes. Guanosine Triphosphate 56-59 interferon alpha 17 Homo sapiens 16-20 31729458-7 2019 Utilizing pre-ranked GSEA, we showed that primary tumors with Survivors were associated with anti-cancer signaling such as INF-alpha/-gamma response and TNF-alpha signaling, compared with all recurrence groups in pre-ranked GSEA. gsea 21-25 interferon alpha 17 Homo sapiens 123-132 30701919-5 2018 Sixty three patients were included in the analysis: the first group consisted of 33 patients who received the therapy with ce-pegiterferone alpha-2b (ce-pegalpha-INF-alpha-2b), 10 of them received previous treatment; the second group - 23 patients btained hydroxycarbamide; the third group - 7 patients were treated with recombinant interferon alpha therapy (rINFalpha). ce-pegiterferone 123-139 interferon alpha 17 Homo sapiens 162-171 30701919-13 2018 Hematologic adverse events (AEs) were more frequently observed in patients receiving ce-pegalpha-INF-alpha-2b therapy. ce-pegalpha 85-96 interferon alpha 17 Homo sapiens 97-106 28914761-9 2017 We observed that in a dose-dependent manner, silybin and silychristin inhibit the IL-1beta-induced formation of blood platelet-leukocyte aggregates in whole blood samples, as well as the production of pro-inflammatory cytokines-IL-2, TNF, INF-alpha, and INF-gamma. Silybin 45-52 interferon alpha 17 Homo sapiens 239-248 28914761-9 2017 We observed that in a dose-dependent manner, silybin and silychristin inhibit the IL-1beta-induced formation of blood platelet-leukocyte aggregates in whole blood samples, as well as the production of pro-inflammatory cytokines-IL-2, TNF, INF-alpha, and INF-gamma. silychristin 57-69 interferon alpha 17 Homo sapiens 239-248 29800615-9 2018 Levels of inflammatory cytokines IL-8, IL-10, IL-6, TNFR2, INF-alpha, and INF-beta were reduced after ruxolitinib treatment. ruxolitinib 102-113 interferon alpha 17 Homo sapiens 59-68 27495085-13 2016 CONCLUSIONS: PEG-INF-alpha2a plus ADV combination therapy is safe and superior to PEG-INF-alpha2amonotherapyfor decreasing serum HBV DNA and normalizing the ALT level but has no significant impact on the rate of HBeAg seroconversion and HBsAg loss. Polyethylene Glycols 13-16 interferon alpha 17 Homo sapiens 17-26 26408730-6 2015 In elderly patients treatment with 5-FU plus FA decreased the risk for an event by 1.5-fold compared to 5-FU (HR=0.657, 95%CI=0.495-0.870, p=0.004) and 5-FU plus INFa (HR=0.685, 95%CI=0.515-0.912, p=0.009). Fluorouracil 35-39 interferon alpha 17 Homo sapiens 162-166 26177560-3 2015 In 2009, a genome wide association study (GWAS) revealed that genetic variants in close proximity to the IL28B (IFNL3) gene predicted greater likelihood of achieving sustained virological response (SVR) following treatment with pegylated IFN-alpha (peg INF-alpha) and ribavirin. Polyethylene Glycols 228-231 interferon alpha 17 Homo sapiens 253-262 26177560-3 2015 In 2009, a genome wide association study (GWAS) revealed that genetic variants in close proximity to the IL28B (IFNL3) gene predicted greater likelihood of achieving sustained virological response (SVR) following treatment with pegylated IFN-alpha (peg INF-alpha) and ribavirin. Ribavirin 268-277 interferon alpha 17 Homo sapiens 253-262 26177560-4 2015 IL28B (rs12979860 and rs8099917) single nucleotide polymorphisms (SNPs) have been recently found among the Pakistani population associated with response to chronic HCV infection INF-alpha + ribavirin therapy. Ribavirin 190-199 interferon alpha 17 Homo sapiens 178-187 24293814-4 2012 Results showed that PolyI.C inhibited viral replication, and increased the level of 2",5"-oligoadenylate synthase mRNA transcripts, a marker of INF-alpha/beta induction. Poly I-C 20-27 interferon alpha 17 Homo sapiens 144-153 17236186-1 2007 A patient with multiple myeloma (MM) was being maintained on human recombinant interferon-alpha (INF-alpha) after VAD and autologous bone marrow transplantation (pretreated with melphalan). Melphalan 178-187 interferon alpha 17 Homo sapiens 97-106 21569385-8 2011 For further research, we will scrutinize the synergistic effect of active antiviral compound in combination with standard PEG INF-alpha and ribavirin which may be helpful in exploring further gateways for antiviral therapy against HCV. Polyethylene Glycols 122-125 interferon alpha 17 Homo sapiens 126-135 18300356-6 2008 RESULTS: Sequential lamivudine- INF-alpha therapy, lamivudine and INF-alpha monotherapy reduced ccc DNA of 1.7 log, 1.4 log and 0.8 log, respectively (P < 0.05). Lamivudine 20-30 interferon alpha 17 Homo sapiens 32-41 18300356-11 2008 CONCLUSION: Forty-eight week sequential lamivudine-INF-alpha therapy and lamivudine monotherapy reduce ccc DNA more significantly than 24-wk INF-alpha monotherapy. Lamivudine 40-50 interferon alpha 17 Homo sapiens 51-60 21272926-9 2011 While INF-alpha showed only slight enhancement of the cell-death effect of PTX in PTX-sensitive cells, INF-alpha itself strongly induced apoptosis in PTX-resistant cells regardless of PTX concentration. Paclitaxel 75-78 interferon alpha 17 Homo sapiens 6-15 21272926-11 2011 SP could be a target of INF-alpha, and resistance to PTX might be overcome by INF-alpha. sp 0-2 interferon alpha 17 Homo sapiens 24-33 21272926-11 2011 SP could be a target of INF-alpha, and resistance to PTX might be overcome by INF-alpha. Paclitaxel 53-56 interferon alpha 17 Homo sapiens 78-87 20206653-5 2010 However, only cleavable siRNA-PEG conjugates significantly reduced the extent of INF-alpha release as compared to noncleavable siRNA-PEG conjugates, suggesting that they can be potentially used for therapeutic siRNA applications. Polyethylene Glycols 30-33 interferon alpha 17 Homo sapiens 81-90 19322075-3 2009 Thus, we studied whether human recombinant INF-alpha (rIFN-alpha) would reinstate morphine-conditioned place preference (CPP) in rats. Morphine 82-90 interferon alpha 17 Homo sapiens 43-52 12490311-4 2003 The distribution of IFNA17 Ile184Arg genotype among SCCA cases (Ile/Ile, 21%; Arg/Ile, 57%; and Arg/Arg, 22%) was different significantly from that among NCC (Ile/Ile, 32%; Arg/Ile, 56%; and Arg/Arg, 12%) (P=0.0345). ile184arg 27-36 interferon alpha 17 Homo sapiens 20-26 17331344-2 2007 In the present study, the effects of repeated pre-treatment with recombinant human INF-alpha (rhIFN-alpha) on oral and intravenous pharmacokinetics of a P-gp substrate, docetaxel (DTX; Taxotere) were investigated in a rat model. Docetaxel 180-183 interferon alpha 17 Homo sapiens 83-92 17331344-2 2007 In the present study, the effects of repeated pre-treatment with recombinant human INF-alpha (rhIFN-alpha) on oral and intravenous pharmacokinetics of a P-gp substrate, docetaxel (DTX; Taxotere) were investigated in a rat model. Docetaxel 185-193 interferon alpha 17 Homo sapiens 83-92 17454786-5 2007 INF-alpha decreased the colony-forming ability and proliferation of the K562 cells and demonstrated a possibly additive effect with busulfan. Busulfan 132-140 interferon alpha 17 Homo sapiens 0-9 16622600-5 2006 A PEG(2,40 K) conjugate of INF-alpha-2b exhibited a 330-fold prolonged plasma half life time compared to the native protein. Polyethylene Glycols 2-5 interferon alpha 17 Homo sapiens 27-36 16041207-2 2005 5-FU cytotoxicity can be modulated by folinic acid (FA) or interferon-alpha (INF-alpha). Fluorouracil 0-4 interferon alpha 17 Homo sapiens 77-86 12490311-4 2003 The distribution of IFNA17 Ile184Arg genotype among SCCA cases (Ile/Ile, 21%; Arg/Ile, 57%; and Arg/Arg, 22%) was different significantly from that among NCC (Ile/Ile, 32%; Arg/Ile, 56%; and Arg/Arg, 12%) (P=0.0345). Isoleucine 27-30 interferon alpha 17 Homo sapiens 20-26 12490311-4 2003 The distribution of IFNA17 Ile184Arg genotype among SCCA cases (Ile/Ile, 21%; Arg/Ile, 57%; and Arg/Arg, 22%) was different significantly from that among NCC (Ile/Ile, 32%; Arg/Ile, 56%; and Arg/Arg, 12%) (P=0.0345). Arginine 33-36 interferon alpha 17 Homo sapiens 20-26 12490311-4 2003 The distribution of IFNA17 Ile184Arg genotype among SCCA cases (Ile/Ile, 21%; Arg/Ile, 57%; and Arg/Arg, 22%) was different significantly from that among NCC (Ile/Ile, 32%; Arg/Ile, 56%; and Arg/Arg, 12%) (P=0.0345). Isoleucine 64-67 interferon alpha 17 Homo sapiens 20-26 12490311-4 2003 The distribution of IFNA17 Ile184Arg genotype among SCCA cases (Ile/Ile, 21%; Arg/Ile, 57%; and Arg/Arg, 22%) was different significantly from that among NCC (Ile/Ile, 32%; Arg/Ile, 56%; and Arg/Arg, 12%) (P=0.0345). Arginine 78-81 interferon alpha 17 Homo sapiens 20-26 12490311-4 2003 The distribution of IFNA17 Ile184Arg genotype among SCCA cases (Ile/Ile, 21%; Arg/Ile, 57%; and Arg/Arg, 22%) was different significantly from that among NCC (Ile/Ile, 32%; Arg/Ile, 56%; and Arg/Arg, 12%) (P=0.0345). Arginine 78-81 interferon alpha 17 Homo sapiens 20-26 12490311-4 2003 The distribution of IFNA17 Ile184Arg genotype among SCCA cases (Ile/Ile, 21%; Arg/Ile, 57%; and Arg/Arg, 22%) was different significantly from that among NCC (Ile/Ile, 32%; Arg/Ile, 56%; and Arg/Arg, 12%) (P=0.0345). Isoleucine 64-67 interferon alpha 17 Homo sapiens 20-26 12490311-4 2003 The distribution of IFNA17 Ile184Arg genotype among SCCA cases (Ile/Ile, 21%; Arg/Ile, 57%; and Arg/Arg, 22%) was different significantly from that among NCC (Ile/Ile, 32%; Arg/Ile, 56%; and Arg/Arg, 12%) (P=0.0345). Isoleucine 64-67 interferon alpha 17 Homo sapiens 20-26 12490311-4 2003 The distribution of IFNA17 Ile184Arg genotype among SCCA cases (Ile/Ile, 21%; Arg/Ile, 57%; and Arg/Arg, 22%) was different significantly from that among NCC (Ile/Ile, 32%; Arg/Ile, 56%; and Arg/Arg, 12%) (P=0.0345). Arginine 78-81 interferon alpha 17 Homo sapiens 20-26 12490311-4 2003 The distribution of IFNA17 Ile184Arg genotype among SCCA cases (Ile/Ile, 21%; Arg/Ile, 57%; and Arg/Arg, 22%) was different significantly from that among NCC (Ile/Ile, 32%; Arg/Ile, 56%; and Arg/Arg, 12%) (P=0.0345). Isoleucine 64-67 interferon alpha 17 Homo sapiens 20-26 12490311-4 2003 The distribution of IFNA17 Ile184Arg genotype among SCCA cases (Ile/Ile, 21%; Arg/Ile, 57%; and Arg/Arg, 22%) was different significantly from that among NCC (Ile/Ile, 32%; Arg/Ile, 56%; and Arg/Arg, 12%) (P=0.0345). Arginine 78-81 interferon alpha 17 Homo sapiens 20-26 12490311-4 2003 The distribution of IFNA17 Ile184Arg genotype among SCCA cases (Ile/Ile, 21%; Arg/Ile, 57%; and Arg/Arg, 22%) was different significantly from that among NCC (Ile/Ile, 32%; Arg/Ile, 56%; and Arg/Arg, 12%) (P=0.0345). Arginine 78-81 interferon alpha 17 Homo sapiens 20-26 10900338-7 2000 These studies show strong structural and functional similarities between INFalpha and opioid peptides, and inferred that the analgesic domain locates around the 122nd Tyr residue of IFNalpha molecule in tertiary structure. Tyrosine 167-170 interferon alpha 17 Homo sapiens 73-81 15080496-5 2002 INF-alpha was encapsulated in different liposomal formulations, Dimyristoylphosphatidylcholine (DMPC), Dioleyl-phosphatidyl-ethanolamine/Dimyristoylphosphatidylcholine (DOPE/DMPC) and DOPE/Dimyristoylphosphatidylglycerol (DOPE/DMPG). Dimyristoylphosphatidylcholine 64-94 interferon alpha 17 Homo sapiens 0-9 15080496-5 2002 INF-alpha was encapsulated in different liposomal formulations, Dimyristoylphosphatidylcholine (DMPC), Dioleyl-phosphatidyl-ethanolamine/Dimyristoylphosphatidylcholine (DOPE/DMPC) and DOPE/Dimyristoylphosphatidylglycerol (DOPE/DMPG). Dimyristoylphosphatidylcholine 96-100 interferon alpha 17 Homo sapiens 0-9 15080496-5 2002 INF-alpha was encapsulated in different liposomal formulations, Dimyristoylphosphatidylcholine (DMPC), Dioleyl-phosphatidyl-ethanolamine/Dimyristoylphosphatidylcholine (DOPE/DMPC) and DOPE/Dimyristoylphosphatidylglycerol (DOPE/DMPG). dioleyl-phosphatidyl-ethanolamine/dimyristoylphosphatidylcholine 103-167 interferon alpha 17 Homo sapiens 0-9 15080496-5 2002 INF-alpha was encapsulated in different liposomal formulations, Dimyristoylphosphatidylcholine (DMPC), Dioleyl-phosphatidyl-ethanolamine/Dimyristoylphosphatidylcholine (DOPE/DMPC) and DOPE/Dimyristoylphosphatidylglycerol (DOPE/DMPG). dioleoyl phosphatidylethanolamine 169-173 interferon alpha 17 Homo sapiens 0-9 15080496-5 2002 INF-alpha was encapsulated in different liposomal formulations, Dimyristoylphosphatidylcholine (DMPC), Dioleyl-phosphatidyl-ethanolamine/Dimyristoylphosphatidylcholine (DOPE/DMPC) and DOPE/Dimyristoylphosphatidylglycerol (DOPE/DMPG). Dimyristoylphosphatidylcholine 174-178 interferon alpha 17 Homo sapiens 0-9 15080496-5 2002 INF-alpha was encapsulated in different liposomal formulations, Dimyristoylphosphatidylcholine (DMPC), Dioleyl-phosphatidyl-ethanolamine/Dimyristoylphosphatidylcholine (DOPE/DMPC) and DOPE/Dimyristoylphosphatidylglycerol (DOPE/DMPG). dope/dimyristoylphosphatidylglycerol 184-220 interferon alpha 17 Homo sapiens 0-9 15080496-5 2002 INF-alpha was encapsulated in different liposomal formulations, Dimyristoylphosphatidylcholine (DMPC), Dioleyl-phosphatidyl-ethanolamine/Dimyristoylphosphatidylcholine (DOPE/DMPC) and DOPE/Dimyristoylphosphatidylglycerol (DOPE/DMPG). dioleoyl phosphatidylethanolamine 184-188 interferon alpha 17 Homo sapiens 0-9 15080496-5 2002 INF-alpha was encapsulated in different liposomal formulations, Dimyristoylphosphatidylcholine (DMPC), Dioleyl-phosphatidyl-ethanolamine/Dimyristoylphosphatidylcholine (DOPE/DMPC) and DOPE/Dimyristoylphosphatidylglycerol (DOPE/DMPG). dimyristoylphosphatidylglycerol 227-231 interferon alpha 17 Homo sapiens 0-9 15080496-12 2002 The results indicate that the MT-IIA mRNA level depends on the liposomal formulation of INF-alpha, and the sustained-time effect of the INF-alpha encapsulated in DMPC liposomes is parallel to that of nonencapsulated INF-alpha over a period of 36 hours. Dimyristoylphosphatidylcholine 162-166 interferon alpha 17 Homo sapiens 136-145 15080496-12 2002 The results indicate that the MT-IIA mRNA level depends on the liposomal formulation of INF-alpha, and the sustained-time effect of the INF-alpha encapsulated in DMPC liposomes is parallel to that of nonencapsulated INF-alpha over a period of 36 hours. Dimyristoylphosphatidylcholine 162-166 interferon alpha 17 Homo sapiens 136-145 11899822-7 2002 Three-month INFa treatment lowered levels of TNFa, GM-KSF and CD95+ expression on monocytes as well as TFR-1b concentration in the serum which correlated with a positive trend in the standard clinicolaboratory and virusological indices in the examinees. gm-ksf 51-57 interferon alpha 17 Homo sapiens 12-16 9180290-1 1997 All-trans retinoic acid (ATRA) has recently been shown to synergize with the inhibitory effect of interferon alpha (IFN alpha) on the growth of malignant cells isolated from solid tumors. Tretinoin 0-23 interferon alpha 17 Homo sapiens 116-125 11127803-1 1999 The present study was designed to investigate the effect of interferon-alpha ( INF-alpha) on the production of leukotrienes (LTs) and superoxide radicals when intact human neutrophils were stimulated with calcium ionophore (A23187). Leukotrienes 111-123 interferon alpha 17 Homo sapiens 79-88 11127803-1 1999 The present study was designed to investigate the effect of interferon-alpha ( INF-alpha) on the production of leukotrienes (LTs) and superoxide radicals when intact human neutrophils were stimulated with calcium ionophore (A23187). Leukotrienes 125-128 interferon alpha 17 Homo sapiens 79-88 11127803-1 1999 The present study was designed to investigate the effect of interferon-alpha ( INF-alpha) on the production of leukotrienes (LTs) and superoxide radicals when intact human neutrophils were stimulated with calcium ionophore (A23187). Superoxides 134-144 interferon alpha 17 Homo sapiens 79-88 11127803-1 1999 The present study was designed to investigate the effect of interferon-alpha ( INF-alpha) on the production of leukotrienes (LTs) and superoxide radicals when intact human neutrophils were stimulated with calcium ionophore (A23187). Calcium 205-212 interferon alpha 17 Homo sapiens 79-88 11127803-1 1999 The present study was designed to investigate the effect of interferon-alpha ( INF-alpha) on the production of leukotrienes (LTs) and superoxide radicals when intact human neutrophils were stimulated with calcium ionophore (A23187). Calcimycin 224-230 interferon alpha 17 Homo sapiens 79-88 11127803-4 1999 Preincubation of intact human neutrophils with INF-alpha and subsequent stimulation with calcium ionophore A23187 also enhanced significantly superoxide radical generation that reduced nitroblue tetrazolium into blue formazan. Calcimycin 107-113 interferon alpha 17 Homo sapiens 47-56 11127803-4 1999 Preincubation of intact human neutrophils with INF-alpha and subsequent stimulation with calcium ionophore A23187 also enhanced significantly superoxide radical generation that reduced nitroblue tetrazolium into blue formazan. Superoxides 142-160 interferon alpha 17 Homo sapiens 47-56 9883313-6 1998 The results of the randomized trails, carried out in France, showed that the combination of IFN-alpha and cytarabine as compared with INF-alpha alone, increases the rate of major cytogenetic response and prolongs survival in the chronic phase of CML. Cytarabine 106-116 interferon alpha 17 Homo sapiens 134-143 10235418-1 1999 Concomitantly we observed an increase of FT4 and FT3 with a totally depressed TSH level 80 days after starting INF-alpha administration. Thyrotropin 78-81 interferon alpha 17 Homo sapiens 111-120 11127803-4 1999 Preincubation of intact human neutrophils with INF-alpha and subsequent stimulation with calcium ionophore A23187 also enhanced significantly superoxide radical generation that reduced nitroblue tetrazolium into blue formazan. Nitroblue Tetrazolium 185-206 interferon alpha 17 Homo sapiens 47-56 11127803-4 1999 Preincubation of intact human neutrophils with INF-alpha and subsequent stimulation with calcium ionophore A23187 also enhanced significantly superoxide radical generation that reduced nitroblue tetrazolium into blue formazan. blue formazan 212-225 interferon alpha 17 Homo sapiens 47-56 11127803-5 1999 The in vivo effect of INF-alpha in rats demonstrated that the higher dose of INF-alpha that induced superoxide radical and LTB4 by A23187 stimulated intact human neutrophil in vitro, also induced a significant decrease in white blood cells and RBCs started at 4 h after i.p administration. Superoxides 100-110 interferon alpha 17 Homo sapiens 22-31 11127803-5 1999 The in vivo effect of INF-alpha in rats demonstrated that the higher dose of INF-alpha that induced superoxide radical and LTB4 by A23187 stimulated intact human neutrophil in vitro, also induced a significant decrease in white blood cells and RBCs started at 4 h after i.p administration. Superoxides 100-110 interferon alpha 17 Homo sapiens 77-86 11127803-5 1999 The in vivo effect of INF-alpha in rats demonstrated that the higher dose of INF-alpha that induced superoxide radical and LTB4 by A23187 stimulated intact human neutrophil in vitro, also induced a significant decrease in white blood cells and RBCs started at 4 h after i.p administration. Calcimycin 131-137 interferon alpha 17 Homo sapiens 77-86 9666567-5 1998 IL-2, IL-3, IL-6, and INF-alpha are able to directly stimulate glucocorticoid production by zona fasciculata and zona reticularis cells, whereas IL-1 exerts an analogous effect through an indirect mechanism involving the stimulation of catecholamine release by chromaffin cells and/or the activation of the intramedullary CRH/ACTH system; again, TNF-alpha depresses glucocorticoid synthesis. Catecholamines 236-249 interferon alpha 17 Homo sapiens 22-31 9666567-5 1998 IL-2, IL-3, IL-6, and INF-alpha are able to directly stimulate glucocorticoid production by zona fasciculata and zona reticularis cells, whereas IL-1 exerts an analogous effect through an indirect mechanism involving the stimulation of catecholamine release by chromaffin cells and/or the activation of the intramedullary CRH/ACTH system; again, TNF-alpha depresses glucocorticoid synthesis. chromaffin 261-271 interferon alpha 17 Homo sapiens 22-31 9180290-6 1997 Addition of ATRA to IFN alpha dramatically potentiated the inhibitory effects of INF alpha on CFU-GM growth. Tretinoin 12-16 interferon alpha 17 Homo sapiens 81-90 9180290-9 1997 RT-PCR analysis of the colonies resulting from the action of the combination IFN alpha plus ATRA showed the presence of an increased number of BCR-ABL-negative colonies relatively to what was observed with IFN alpha alone. Tretinoin 92-96 interferon alpha 17 Homo sapiens 206-215 9180290-2 1997 We investigated whether ATRA could potentiate the inhibitory effects of IFN alpha on the proliferation of leukemic progenitors in chronic myeloid leukemia (CML). Tretinoin 24-28 interferon alpha 17 Homo sapiens 72-81 9180290-6 1997 Addition of ATRA to IFN alpha dramatically potentiated the inhibitory effects of INF alpha on CFU-GM growth. Tretinoin 12-16 interferon alpha 17 Homo sapiens 20-29 1423240-3 1992 This antagonistic effect is paralleled by the ability of tamoxifen to modulate the INF-alpha-induced hyperpolarization in these cells. Tamoxifen 57-66 interferon alpha 17 Homo sapiens 83-92 8727047-8 1996 Addition of phorbol esters to CHRF-288-11 cells enhances their megakaryocytic phenotype; such treatment also results in increased secretion of INF-alpha, TNF-alpha, and GM-CSF. Phorbol Esters 12-26 interferon alpha 17 Homo sapiens 143-152 7798436-3 1994 After oral etretinate with a dosage of 50 mg daily was combined with INF-alpha, marked clinical improvement was seen in skin lesions with minor side effects. Etretinate 11-21 interferon alpha 17 Homo sapiens 69-78 8690043-4 1996 In Northern blot experiments, expression of IL-11 mRNA was reduced in the presence of INF-alpha; this inhibiton was prevented by the addition of cycloheximide. Cycloheximide 145-158 interferon alpha 17 Homo sapiens 86-95 8179244-6 1993 INF-alpha is also used in histiocytosis X alone or in combination with retinoids or with etoposide and has been found effective in several observations. Retinoids 71-80 interferon alpha 17 Homo sapiens 0-9 8179244-6 1993 INF-alpha is also used in histiocytosis X alone or in combination with retinoids or with etoposide and has been found effective in several observations. Etoposide 89-98 interferon alpha 17 Homo sapiens 0-9 8179244-7 1993 In carcinoid syndromes whether treated priorly or not with a 5-fluoro-uracil-streptozoticin combination, INF-alpha leads to an objective response in two-thirds of the patients. Fluorouracil 61-76 interferon alpha 17 Homo sapiens 105-114 8179244-7 1993 In carcinoid syndromes whether treated priorly or not with a 5-fluoro-uracil-streptozoticin combination, INF-alpha leads to an objective response in two-thirds of the patients. Streptozocin 77-91 interferon alpha 17 Homo sapiens 105-114 2965208-4 1988 At 300 pM, H2O2-releasing capacity was enhanced 4.4 +/- 1.6-fold over medium control (mean +/- SD for natural INF-alpha, rIFN-alpha A, rIFN-alpha D, and rIFN-beta) compared to an 8.4 +/- 4.8-fold increase with rIFN-gamma (100 pM, 100 U/ml) in the same experiments. Hydrogen Peroxide 11-15 interferon alpha 17 Homo sapiens 110-119 1906352-6 1991 Thus, the enhanced attachment by primitive CML progenitor cells to INF-alpha-treated stromal cells might be due to changes in the neuraminic acid composition in the stromal cell layer. Neuraminic Acids 130-145 interferon alpha 17 Homo sapiens 67-76