PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
12917348-1	2003	The yeast IMD2 to IMD4 and GUA1 genes, involved in GMP synthesis, are highly expressed in exponentially growing cells but are shut off when cells cease to grow upon nutrient limitation.	guanosine 5'-monophosphorothioate	51-54	GMP synthase (glutamine-hydrolyzing)	Saccharomyces cerevisiae S288C	27-31
11035032-4	2001	Only this first step of GDP synthesis pathway is regulated, since the latter steps, encoded by the GUA1 and GUK1 genes, are guanine-insensitive.	Guanosine Diphosphate	24-27	GMP synthase (glutamine-hydrolyzing)	Saccharomyces cerevisiae S288C	99-103
11035032-4	2001	Only this first step of GDP synthesis pathway is regulated, since the latter steps, encoded by the GUA1 and GUK1 genes, are guanine-insensitive.	Guanine	124-131	GMP synthase (glutamine-hydrolyzing)	Saccharomyces cerevisiae S288C	99-103
20980241-3	2011	We have identified a substitution mutation (G388D) that reduces the activity of the GMP synthase Gua1 in budding yeast and the total G-nucleotide pool, leading to precipitous reductions in the GDP/GTP ratio and ATP level in vivo.	Guanosine Diphosphate	193-196	GMP synthase (glutamine-hydrolyzing)	Saccharomyces cerevisiae S288C	97-101
20980241-3	2011	We have identified a substitution mutation (G388D) that reduces the activity of the GMP synthase Gua1 in budding yeast and the total G-nucleotide pool, leading to precipitous reductions in the GDP/GTP ratio and ATP level in vivo.	Guanosine Triphosphate	197-200	GMP synthase (glutamine-hydrolyzing)	Saccharomyces cerevisiae S288C	97-101
20980241-3	2011	We have identified a substitution mutation (G388D) that reduces the activity of the GMP synthase Gua1 in budding yeast and the total G-nucleotide pool, leading to precipitous reductions in the GDP/GTP ratio and ATP level in vivo.	Adenosine Triphosphate	211-214	GMP synthase (glutamine-hydrolyzing)	Saccharomyces cerevisiae S288C	97-101
20980241-7	2011	Consistently, addition of an external supply of guanine reverts all the phenotypes of gua1-G388D cells, but not those of gua1-G388D Deltahpt1 mutants unable to refill the internal GMP pool through the salvage pathway.	Guanine	48-55	GMP synthase (glutamine-hydrolyzing)	Saccharomyces cerevisiae S288C	86-90